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Gene: ZCCHC4 (zinc finger CCHC-type containing 4) Homo sapiens
Symbol: ZCCHC4
Name: zinc finger CCHC-type containing 4
Description: Exhibits S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Localizes to cytoplasm and nucleolus; INTERACTS WITH aflatoxin B1; antirheumatic drug; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DHHC domain-containing zinc finger protein; HSPC052; MGC21108; rRNA N6-adenosine-methyltransferase ZCCHC4; ZGRF4; zinc finger CCHC domain-containing protein 4; zinc finger, CCHC domain containing 4; zinc finger, GRF-type containing 4
Mus musculus (house mouse) : Zcchc4 (zinc finger, CCHC domain containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zcchc4 (zinc finger CCHC-type containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zcchc4 (zinc finger CCHC-type containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ZCCHC4 (zinc finger CCHC-type containing 4)
Canis lupus familiaris (dog) : ZCCHC4 (zinc finger CCHC-type containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zcchc4 (zinc finger CCHC-type containing 4)
Sus scrofa (pig) : ZCCHC4 (zinc finger CCHC-type containing 4)
Chlorocebus sabaeus (African green monkey) : ZCCHC4 (zinc finger CCHC-type containing 4)
Heterocephalus glaber (naked mole-rat) : Zcchc4 (zinc finger CCHC-type containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl425,312,774 - 25,370,383 (+)EnsemblGRCh38hg38GRCh38
GRCh38425,312,774 - 25,373,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37425,314,396 - 25,374,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,923,494 - 24,981,103 (+)NCBINCBI36hg18NCBI36
Build 34424,990,708 - 25,027,576NCBI
Celera425,763,095 - 25,820,709 (+)NCBI
Cytogenetic Map4p15.2NCBI
HuRef424,654,540 - 24,712,182 (+)NCBIHuRef
CHM1_1425,314,026 - 25,371,618 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZCCHC4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322864
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.