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Ontology Browser

Term:
6-de(cyclopropylamino)-6-(2,2-dimethylazetidin-1-yl)abacavir (CHEBI:149430)
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Parent Terms Term With Siblings Child Terms
2,6-diaminopurines +     
abacavir +   
(+)-larreatricin 
(+-)-chartaceone C 
(+-)-chartaceone D 
(+-)-chartaceone E 
(+-)-chartaceone F 
(-)-antofine  
(E)-2-[[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]benzoic acid 
(E,E)-germacrone  
(R)-DRF053 +  
(R)-goitrin +   
(R,R,R)-alpha-tocopherol +   
(S)-goitrin +   
1-monolinolein +  
13,14-dihydro-Delta(12)-prostaglandin J2  
2,2'-spirobi[3,6,7,8-tetrahydro-1H-cyclopenta[g]naphthalene]-5,5'-dione 
2-amino-6-hydroxyaminopurine 
3'-deoxy-3',4'-didehydro-CTP 
3'-deoxy-3',4'-didehydro-cytidine +  
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride  
5'-triphosphoadenylyl-(2'->5')-adenosine 
5-\{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl\}-3-methylisoxazole 
6-azathymidine 
6-de(cyclopropylamino)-6-(2,2-dimethylazetidin-1-yl)abacavir 
A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by a 2,2-dimethylazetidin-1-yl group. One of a series of synthesised abacavir analogues with antiviral activity found to stimulate IFN-gamma secretion in abacavir-responsive clones.
6-de(cyclopropylamino)-6-(2-methylazetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(3-cyclopropyl-3-fluoroazetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(3-fluoroazetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(3-isopropoxyazetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(3-methoxyazetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(azetidin-1-yl)abacavir 
6-de(cyclopropylamino)-6-(isobutylamino)abacavir 
6-de(cyclopropylamino)-6-(isopropylamino)abacavir 
6-de(cyclopropylamino)-6-[(S)-sec-butylamino]abacavir 
6-diazo-5-oxo-L-norleucine 
7,4'-di-O-galloyltricetiflavan 
7-O-galloyltricetiflavan 
9H-purine-2,6-diamine +  
abacavir +   
abacavir 5'-carboxylic acid 
abacavir 5'-glucuronide 
abacavir monophosphate 
abacavir sulfate 
agathisflavone  
amantadine hydrochloride 
amentoflavone +   
anti-HBV agent +   
anti-HIV agent +   
anti-HSV agent +   
anticoronaviral agent +   
antiviral drug +   
aranotin 
ARS-1620  
aspirin-triggered resolvin D1 
aspulvinone E 
baricitinib  
benzethonium chloride  
betulin +   
blancoxanthone 
brequinar  
brequinar sodium 
bromotopsentin 
buformin 
camostat  
camostat mesylate 
CHIR-265 
chloroinconazide 
chrysophanol +   
chrysosplenetin  
chrysosplenol C 
cinanserin 
cinanserin hydrochloride 
cordycepin triphosphate 
cryptopleurine 
cytarabine  
cytonic acid A 
cytonic acid B 
daphnoretin 
daprodustat 
decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone 
deguelin  
desacetylpyramidaglain D 
dextran sulfate  
dioscin  
diosgenin +   
dithiodiphosphoric acid +   
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor +   
emetine +   
emetine dihydrochloride +  
emetine dihydrochloride hydrate 
etravirine 
eudistomin C 
ferric ammonium citrate  
flavasperone 
fludarabine phosphate 
fustin +  
ganoderol B  
geldanamycin +   
ginsenoside Rb2  
gramine  
GS-441524 +   
herquline A 
hesseltin A 
hypothiocyanous acid 
isoaspulvinone E 
isorhapontigenin  
L-psicose 
ladanein 
LDC4297 
lucidumoside C 
MI-1148 
minquartynoic acid 
N(4)-hydroxycytidine +   
N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-\{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl\}-L-leucinamide 
N-hydroxyguanidine 
N-nonyldeoxynojirimycin 
nonstructural protein 5A inhibitor +  
NSC 23766 +   
NSC 23766 trihydrochloride 
oblonganoside A 
olomoucine  
pateamine 
phenethyl caffeate  
phosphonoacetic acid +   
porfimer 
porfimer sodium 
purpurester A 
purpurquinone B 
purvalanol +  
pyranojacareubin 
quercetagetin +   
rhapontigenin +   
rhinacanthin C 
rhinacanthin D 
ribavirin +   
ribavirin 5'-diphosphate 
ribavirin 5'-monophosphate 
ribavirin 5'-triphosphate 
SDZ 35-682 
seliciclib  
SG85 
simalikalactone D 
spectinabilin 
stavudine  
sugiol +  
surfactin  
surfactin A +   
surfactin B +   
surfactin C +   
surfactin D +   
TAN-931 
tert-butyl N-\{1-[(1S)-1-\{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl\}-2-cyclopropylethyl]-2-oxopyridin-3-yl\}carbamate 
tilorone  
tiratricol  
topopyrone A 
topopyrone B 
topopyrone C 
topopyrone D 
torvoside H 
triptofordin C 2 
tyrphostin AG 1478  
UNC0638 
valinomycin  
vobasine 
xanthohumol  
zanamivir 

Synonyms
Exact Synonyms: {(1S,4R)-4-[2-amino-6-(2,2-dimethylazetidin-1-yl)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
Related Synonyms: (1S,4R)-4-[2-amino-6-(2,2-dimethyl-1-azetidinyl)-9H-purin-9-yl]-2-cyclopentene-1-methanol ;   Formula=C16H22N6O ;   InChI=1S/C16H22N6O/c1-16(2)5-6-22(16)14-12-13(19-15(17)20-14)21(9-18-12)11-4-3-10(7-11)8-23/h3-4,9-11,23H,5-8H2,1-2H3,(H2,17,19,20)/t10-,11+/m1/s1 ;   InChIKey=AZNKZYXEUMQLIU-MNOVXSKESA-N ;   SMILES=[C@H]1(C=C[C@@H](C1)N2C=3C(N=C2)=C(N=C(N3)N)N4CCC4(C)C)CO
Xrefs: PMID:31549414

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