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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quercetagetin
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Accession:CHEBI:8695 term browser browse the term
Definition:A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 5, 6, 7, 3' and 4' respectively.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one
 related_synonym: 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4-benzopyrone;   3,3',4',5,6,7-hexahydroxyflavone;   6-Hydroxyquercetin;   Formula=C15H10O8;   InChI=1S/C15H10O8/c16-6-2-1-5(3-7(6)17)15-14(22)13(21)10-9(23-15)4-8(18)11(19)12(10)20/h1-4,16-20,22H;   InChIKey=ZVOLCUVKHLEPEV-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1O)-c1oc2cc(O)c(O)c(O)c2c(=O)c1O
 xref: CAS:90-18-6;   KEGG:C10122;   KNApSAcK:C00004677;   LIPID_MAPS_instance:LMPK12112983
 xref_mesh: MESH:C079163
 xref: PDBeChem:MYU;   PMID:20685402;   PMID:22223143;   PMID:23000494;   PMID:23142567;   Patent:KR20120035741;   Reaxys:332041;   Wikipedia:Quercetagetin


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quercetagetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP quercetagetin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of AKT1 protein] CTD PMID:20685402 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ar androgen receptor multiple interactions EXP quercetagetin inhibits the reaction [decamethrin results in increased phosphorylation of AR protein] CTD PMID:25299849 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP quercetagetin inhibits the reaction [lipoteichoic acid results in increased expression of IL1B] CTD PMID:20685402 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP quercetagetin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK1 protein] CTD PMID:20685402 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP quercetagetin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK3 protein] CTD PMID:20685402 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pla2g2a phospholipase A2 group IIA affects activity ISO quercetagetin affects the activity of PLA2G2A protein CTD PMID:8190018 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
casticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO casticin results in increased expression of ABCC5 mRNA CTD PMID:28444820 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Adam10 ADAM metallopeptidase domain 10 increases expression ISO casticin results in increased expression of ADAM10 mRNA CTD PMID:28444820 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
JBrowse link
G Aftph aftiphilin decreases expression ISO casticin results in decreased expression of AFTPH mRNA CTD PMID:28444820 NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376
JBrowse link
G Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 decreases expression ISO casticin results in decreased expression of AGAP1 mRNA CTD PMID:28444820 NCBI chr 9:90,039,760...90,475,196
Ensembl chr 9:90,039,605...90,470,958
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression
multiple interactions
ISO casticin results in increased expression of AIFM1 protein
[Fluorouracil co-treated with casticin] results in increased expression of AIFM1 protein
CTD PMID:29098808 PMID:32270916 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akirin2 akirin 2 decreases expression ISO casticin results in decreased expression of AKIRIN2 mRNA CTD PMID:28444820 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO casticin results in decreased expression of AKT1 protein CTD PMID:28444820 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases expression ISO casticin results in decreased expression of AKT3 mRNA CTD PMID:27862857 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO casticin results in increased expression of ALDH1A1 mRNA CTD PMID:27862857 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alx1 ALX homeobox 1 decreases expression ISO casticin results in decreased expression of ALX1 mRNA CTD PMID:28444820 NCBI chr 7:38,157,626...38,177,220
Ensembl chr 7:38,147,117...38,177,220
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO casticin results in increased expression of APAF1 protein CTD PMID:27862857 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 decreases expression ISO casticin results in decreased expression of ARL6IP4 mRNA CTD PMID:28444820 NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799
JBrowse link
G Armc9 armadillo repeat containing 9 decreases expression ISO casticin results in decreased expression of ARMC9 mRNA CTD PMID:28444820 NCBI chr 9:86,802,791...86,928,860
Ensembl chr 9:86,802,868...86,928,860
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO casticin results in decreased expression of ARNTL mRNA CTD PMID:28444820 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like decreases expression ISO casticin results in decreased expression of ARPC5L mRNA CTD PMID:28444820 NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO casticin results in decreased expression of ASNS mRNA CTD PMID:28444820 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO casticin results in decreased expression of ATF5 mRNA CTD PMID:28444820 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO casticin results in increased expression of ATF6 protein CTD PMID:27862857 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO casticin results in decreased expression of ATM protein CTD PMID:29098808 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression ISO casticin results in increased expression of ATOX1 mRNA CTD PMID:28444820 NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 decreases expression ISO casticin results in decreased expression of ATP6V1G1 mRNA CTD PMID:28444820 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 increases expression ISO casticin results in increased expression of ATP8A1 mRNA CTD PMID:28444820 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO casticin results in decreased expression of ATR protein CTD PMID:29098808 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atxn7l3b ataxin 7-like 3B decreases expression ISO casticin results in decreased expression of ATXN7L3B mRNA CTD PMID:28444820 NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression ISO casticin results in decreased expression of AVPR1A mRNA CTD PMID:28444820 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Axin2 axin 2 increases expression ISO casticin results in increased expression of AXIN2 mRNA CTD PMID:27862857 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO casticin results in increased expression of BAK1 protein CTD PMID:27862857 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO casticin results in increased expression of BAMBI mRNA CTD PMID:27862857 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO casticin results in decreased expression of BASP1 mRNA CTD PMID:28444820 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO casticin results in increased expression of BAX protein
casticin inhibits the reaction [Fluorouracil results in increased expression of BAX protein]
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO casticin results in decreased expression of BCL11A mRNA CTD PMID:28444820 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO casticin results in decreased expression of BCL2 protein
[Fluorouracil co-treated with casticin] results in decreased expression of BCL2 protein
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
increases expression
ISO casticin results in decreased expression of BCL2L1 protein
casticin promotes the reaction [Fluorouracil results in decreased expression of BCL2L1 protein]; Fluorouracil promotes the reaction [casticin results in decreased expression of BCL2L1 protein]
casticin results in increased expression of BCL2L1 mRNA
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist increases expression
multiple interactions
decreases expression
ISO casticin results in increased expression of BID protein
casticin inhibits the reaction [Fluorouracil results in increased expression of BID protein]
casticin results in decreased expression of BID protein
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of BMI1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of BMI1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of BMI1 mRNA] CTD PMID:32268151 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO casticin results in increased expression of BMP4 mRNA CTD PMID:27862857 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bnip2 BCL2 interacting protein 2 decreases expression ISO casticin results in decreased expression of BNIP2 mRNA CTD PMID:27862857 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO casticin results in increased expression of BRCA1 protein CTD PMID:29098808 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO casticin results in decreased expression of BTF3 mRNA CTD PMID:28444820 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO casticin results in decreased expression of BTG1 mRNA CTD PMID:28444820 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO casticin results in increased expression of CADM1 mRNA CTD PMID:28444820 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 decreases expression ISO casticin results in decreased expression of CALCOCO1 mRNA CTD PMID:28444820 NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO casticin results in decreased expression of CALM1 mRNA CTD PMID:28444820 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO casticin results in decreased expression of CAMK4 mRNA CTD PMID:27862857 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Capn1 calpain 1 multiple interactions ISO casticin results in increased expression of and results in increased cleavage of CAPN1 protein CTD PMID:27862857 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Capn2 calpain 2 increases expression ISO casticin results in increased expression of CAPN2 protein CTD PMID:27862857 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Casp2 caspase 2 increases expression ISO casticin results in increased expression of CASP2 protein CTD PMID:27862857 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO casticin results in increased cleavage of and results in increased activity of CASP3 protein
casticin inhibits the reaction [Fluorouracil results in increased activity of CASP3 protein]
casticin results in increased activity of CASP3 protein
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression ISO casticin results in increased expression of CASP4 protein CTD PMID:27862857 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp6 caspase 6 increases expression ISO casticin results in increased expression of CASP6 protein CTD PMID:27862857 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression ISO casticin results in increased expression of CASP7 protein CTD PMID:27862857 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO casticin results in increased cleavage of and results in increased activity of CASP8 protein; casticin results in increased expression of and results in increased activity of CASP8 protein CTD PMID:27862857 PMID:29098808 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO casticin results in increased cleavage of and results in increased activity of CASP9 protein
casticin promotes the reaction [Fluorouracil results in increased activity of CASP9 protein]
casticin results in increased activity of CASP9 protein
CTD PMID:27862857 PMID:29098808 PMID:32270916 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO casticin results in increased expression of CAT protein
Fluorouracil inhibits the reaction [casticin results in increased expression of CAT protein]
CTD PMID:32270916 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccdc122 coiled-coil domain containing 122 increases expression ISO casticin results in increased expression of CCDC122 mRNA CTD PMID:28444820 NCBI chr15:52,407,806...52,470,050
Ensembl chr15:52,407,717...52,470,163
JBrowse link
G Ccdc174 coiled-coil domain containing 174 decreases expression ISO casticin results in decreased expression of CCDC174 mRNA CTD PMID:28444820 NCBI chr 4:124,392,183...124,419,035
Ensembl chr 4:124,392,274...124,419,035
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO casticin results in decreased expression of CCDC90B mRNA CTD PMID:28444820 NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO casticin results in increased expression of CCN1 mRNA CTD PMID:28444820 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO casticin results in decreased expression of CCNB1 protein CTD PMID:29098808 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 decreases expression ISO casticin results in decreased expression of CCT4 mRNA CTD PMID:28444820 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cd24 CD24 molecule increases expression ISO casticin results in increased expression of CD24 mRNA CTD PMID:27862857 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression
multiple interactions
ISO casticin results in decreased expression of CD44 mRNA; casticin results in decreased expression of CD44 protein
casticin affects the reaction [MIR148A mRNA affects the expression of CD44 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of CD44 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of CD44 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of CD44 protein]
CTD PMID:32268151 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd83 CD83 molecule decreases expression ISO casticin results in decreased expression of CD83 mRNA CTD PMID:27862857 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO casticin results in decreased expression of CDC25C protein CTD PMID:29098808 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO casticin results in decreased expression of CDC42 mRNA CTD PMID:28444820 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdh17 cadherin 17 increases expression ISO casticin results in increased expression of CDH17 mRNA CTD PMID:27862857 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression ISO casticin results in increased expression of CDK2 protein CTD PMID:29098808 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO casticin results in decreased expression of CDKN1A mRNA; casticin results in decreased expression of CDKN1A protein CTD PMID:27862857 PMID:29098808 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO casticin results in increased expression of CDKN1B mRNA CTD PMID:27862857 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO casticin results in increased expression of CDKN2A protein CTD PMID:29098808 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO casticin results in increased expression of CHEK2 protein CTD PMID:29098808 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 decreases expression ISO casticin results in decreased expression of CHIC2 mRNA CTD PMID:28444820 NCBI chr14:33,157,669...33,192,015
Ensembl chr14:33,157,537...33,191,895
JBrowse link
G Cldn1 claudin 1 decreases expression ISO casticin results in decreased expression of CLDN1 mRNA CTD PMID:27862857 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO casticin results in decreased expression of CNBP mRNA CTD PMID:28444820 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO casticin results in decreased expression of COL1A1 mRNA CTD PMID:27862857 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpe carboxypeptidase E increases expression ISO casticin results in increased expression of CPE mRNA CTD PMID:28444820 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO casticin results in increased expression of CREB1 mRNA CTD PMID:27862857 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression ISO casticin results in decreased expression of CRHBP mRNA CTD PMID:28444820 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
G Crls1 cardiolipin synthase 1 decreases expression ISO casticin results in decreased expression of CRLS1 mRNA CTD PMID:28444820 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Cryab crystallin, alpha B increases expression ISO casticin results in increased expression of CRYAB mRNA CTD PMID:28444820 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases expression ISO casticin results in decreased expression of CSNK1A1 mRNA CTD PMID:28444820 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 decreases expression ISO casticin results in decreased expression of CYB5R1 mRNA CTD PMID:28444820 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO casticin results in increased expression of CYCS protein CTD PMID:27862857 PMID:29098808 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO casticin results in decreased expression of DDIT3 mRNA CTD PMID:28444820 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx27 DEAD-box helicase 27 decreases expression ISO casticin results in decreased expression of DDX27 mRNA CTD PMID:28444820 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
JBrowse link
G Dip2c disco-interacting protein 2 homolog C decreases expression ISO casticin results in decreased expression of DIP2C mRNA CTD PMID:28444820 NCBI chr17:60,647,346...61,032,467
Ensembl chr17:60,649,065...61,032,305
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 decreases expression ISO casticin results in decreased expression of DKK3 mRNA CTD PMID:27862857 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases activity
decreases expression
ISO casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein]; casticin affects the reaction [MIR148A mRNA affects the expression of DNMT1 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased activity of DNMT1 protein]; casticin results in decreased expression of and results in decreased activity of DNMT1 protein; DNMT1 protein inhibits the reaction [casticin results in decreased activity of DNMT1 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of BMI1 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of CD44 protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of EPCAM protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of NANOG protein]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of POU5F1 protein]; DNMT1 protein inhibits the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA affects the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA affects the reaction [casticin results in decreased expression of DNMT1 mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased activity of DNMT1 protein] CTD PMID:32268151 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO casticin results in decreased expression of DUSP6 mRNA CTD PMID:28444820 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases expression ISO casticin results in decreased expression of DYRK1A mRNA CTD PMID:28444820 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO casticin results in decreased expression of EGFR protein CTD PMID:28444820 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO casticin results in decreased expression of EIF2S2 mRNA CTD PMID:28444820 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO casticin results in decreased expression of EIF5 mRNA CTD PMID:28444820
G Enc1 ectodermal-neural cortex 1 increases expression ISO casticin results in increased expression of ENC1 mRNA CTD PMID:27862857 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Endog endonuclease G decreases expression
increases expression
multiple interactions
ISO casticin results in decreased expression of ENDOG protein
casticin results in increased expression of ENDOG protein
casticin inhibits the reaction [Fluorouracil results in increased expression of ENDOG protein]
CTD PMID:29098808 PMID:32270916 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO casticin results in decreased expression of EP300 mRNA CTD PMID:27862857 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epb41l4b erythrocyte membrane protein band 4.1 like 4B decreases expression ISO casticin results in decreased expression of EPB41L4B mRNA CTD PMID:28444820 NCBI chr 5:71,691,706...71,852,039
Ensembl chr 5:71,694,331...71,851,990
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of EPCAM mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of EPCAM protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of EPCAM mRNA] CTD PMID:32268151 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 increases expression ISO casticin results in increased expression of ERBB3 mRNA CTD PMID:27862857 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog decreases expression ISO casticin results in decreased expression of ESF1 mRNA CTD PMID:28444820 NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
JBrowse link
G Exosc3 exosome component 3 decreases expression ISO casticin results in decreased expression of EXOSC3 mRNA CTD PMID:28444820 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO casticin results in increased expression of EXT1 mRNA CTD PMID:28444820 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fadd Fas associated via death domain increases expression ISO casticin results in increased expression of FADD protein CTD PMID:27862857 PMID:29098808 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression ISO casticin results in increased expression of FAM227A mRNA CTD PMID:28444820 NCBI chr 7:111,174,362...111,216,513
Ensembl chr 7:111,174,362...111,216,483
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO casticin results in increased expression of FAS protein CTD PMID:27862857 PMID:29098808 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression
decreases expression
ISO casticin results in increased expression of FASLG protein
casticin results in decreased expression of FASLG protein
CTD PMID:27862857 PMID:29098808 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fbxo11 F-box protein 11 decreases expression ISO casticin results in decreased expression of FBXO11 mRNA CTD PMID:28444820 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
JBrowse link
G Fbxo44 F-box protein 44 decreases expression ISO casticin results in decreased expression of FBXO44 mRNA CTD PMID:28444820 NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 decreases expression ISO casticin results in decreased expression of FEZ1 mRNA CTD PMID:28444820 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Foxo3 forkhead box O3 decreases expression ISO casticin results in decreased expression of FOXO3 mRNA CTD PMID:27862857 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp2 forkhead box P2 decreases expression ISO casticin results in decreased expression of FOXP2 mRNA CTD PMID:28444820 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO casticin results in decreased expression of GADD45A mRNA CTD PMID:28444820 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO casticin results in decreased expression of GLUD1 mRNA CTD PMID:28444820 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gphn gephyrin decreases expression ISO casticin results in decreased expression of GPHN mRNA CTD PMID:28444820 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Gpr85 G protein-coupled receptor 85 decreases expression ISO casticin results in decreased expression of GPR85 mRNA CTD PMID:28444820 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO casticin results in decreased expression of GRB2 protein CTD PMID:28444820 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 decreases expression ISO casticin results in decreased expression of GRID2 mRNA CTD PMID:27862857 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression ISO casticin results in decreased expression of HCN2 mRNA CTD PMID:27862857 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
JBrowse link
G Hoxb8 homeo box B8 decreases expression ISO casticin results in decreased expression of HOXB8 mRNA CTD PMID:28444820 NCBI chr10:81,248,313...81,251,261
Ensembl chr10:81,248,887...81,250,638
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO casticin results in decreased expression of HOXB9 mRNA CTD PMID:27862857 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression ISO casticin results in decreased expression of HSPA4 mRNA CTD PMID:28444820 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO casticin results in increased expression of HSPA5 protein CTD PMID:27862857 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO casticin results in increased expression of HSPA8 mRNA CTD PMID:28444820 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO casticin results in decreased expression of HSPA9 mRNA CTD PMID:28444820 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Il12a interleukin 12A decreases expression ISO casticin results in decreased expression of IL12A mRNA CTD PMID:27862857 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il6 interleukin 6 decreases expression ISO casticin results in decreased expression of IL6 mRNA CTD PMID:27862857 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO casticin results in decreased expression of INTS6 mRNA CTD PMID:28444820 NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527
JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 increases expression ISO casticin results in increased expression of IRAK4 mRNA CTD PMID:27862857 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression ISO casticin results in decreased expression of IRF2BP2 mRNA CTD PMID:28444820 NCBI chr19:54,559,409...54,564,714 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases expression ISO casticin results in decreased expression of KCNH2 mRNA CTD PMID:28444820 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 decreases expression ISO casticin results in decreased expression of KCTD9 mRNA CTD PMID:28444820 NCBI chr15:41,942,165...41,969,862
Ensembl chr15:41,942,381...41,969,862
JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO casticin results in decreased expression of KIRREL3 mRNA CTD PMID:28444820 NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676
JBrowse link
G Klf9 Kruppel-like factor 9 decreases expression ISO casticin results in decreased expression of KLF9 mRNA CTD PMID:28444820 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Krt16 keratin 16 increases expression ISO casticin results in increased expression of KRT16 mRNA CTD PMID:28444820 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Ldhb lactate dehydrogenase B decreases expression ISO casticin results in decreased expression of LDHB mRNA CTD PMID:27862857 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 decreases expression ISO casticin results in decreased expression of LEF1 mRNA CTD PMID:27862857 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO casticin results in increased expression of LHFP mRNA CTD PMID:28444820 NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443
JBrowse link
G Limch1 LIM and calponin homology domains 1 increases expression ISO casticin results in increased expression of LIMCH1 mRNA CTD PMID:28444820 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G LOC102553180 protocadherin alpha-1-like increases expression ISO casticin results in increased expression of PCDHA1 mRNA CTD PMID:28444820
G Lpl lipoprotein lipase decreases expression ISO casticin results in decreased expression of LPL mRNA CTD PMID:27862857 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO casticin results in increased expression of LRP5 mRNA CTD PMID:27862857 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Ltv1 LTV1 ribosome biogenesis factor decreases expression ISO casticin results in decreased expression of LTV1 mRNA CTD PMID:28444820 NCBI chr 1:7,565,673...7,578,398
Ensembl chr 1:7,565,669...7,578,563
JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO casticin results in decreased expression of MAF mRNA CTD PMID:28444820 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Magoh mago homolog, exon junction complex subunit decreases expression ISO casticin results in decreased expression of MAGOH mRNA CTD PMID:28444820 NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases expression ISO casticin results in increased expression of MAP3K7 mRNA CTD PMID:27862857 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO casticin results in increased expression of MAPRE2 mRNA CTD PMID:28444820 NCBI chr18:15,028,675...15,169,553 JBrowse link
G Mark3 microtubule affinity regulating kinase 3 decreases expression ISO casticin results in decreased expression of MARK3 mRNA CTD PMID:28444820 NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
JBrowse link
G Max MYC associated factor X decreases expression ISO casticin results in decreased expression of MAX mRNA CTD PMID:28444820 NCBI chr 6:95,636,857...95,662,204
Ensembl chr 6:95,636,858...95,662,137
JBrowse link
G Mbp myelin basic protein increases expression ISO casticin results in increased expression of MBP mRNA CTD PMID:28444820 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO casticin results in decreased expression of MCL1 protein CTD PMID:27862857 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases expression ISO casticin results in increased expression of MDC1 protein CTD PMID:29098808 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Mecom MDS1 and EVI1 complex locus decreases expression ISO casticin results in decreased expression of MECOM mRNA CTD PMID:28444820 NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Mest mesoderm specific transcript increases expression ISO casticin results in increased expression of MEST mRNA CTD PMID:28444820 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Mettl3 methyltransferase-like 3 decreases expression ISO casticin results in decreased expression of METTL3 mRNA CTD PMID:28444820 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041
JBrowse link
G Mir148a microRNA 148a increases expression
multiple interactions
ISO casticin results in increased expression of MIR148A mRNA
casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein]; casticin affects the reaction [MIR148A mRNA affects the expression of CD44 mRNA]; casticin affects the reaction [MIR148A mRNA affects the expression of DNMT1 mRNA]; casticin affects the reaction [MIR148A mRNA results in increased expression of MIR148A mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased activity of DNMT1 protein]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of BMI1 mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of CD44 protein]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of EPCAM mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of NANOG mRNA]; casticin promotes the reaction [MIR148A mRNA results in decreased expression of POU5F1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA affects the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA affects the reaction [casticin results in decreased expression of DNMT1 mRNA]; MIR148A mRNA affects the reaction [casticin results in increased expression of MIR148A mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased activity of DNMT1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of BMI1 mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of CD44 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of EPCAM mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of NANOG mRNA]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of POU5F1 mRNA]
CTD PMID:32268151 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO casticin results in decreased expression of MMP2 mRNA
casticin results in decreased expression of MMP2 protein
CTD PMID:27862857 PMID:28444820 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO casticin results in decreased expression of MMP9 protein CTD PMID:28444820 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mplkip M-phase specific PLK1 interacting protein decreases expression ISO casticin results in decreased expression of MPLKIP mRNA CTD PMID:28444820 NCBI chr17:47,373,624...47,376,199
Ensembl chr17:47,373,845...47,376,204
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 increases expression ISO casticin results in increased expression of MRPL9 mRNA CTD PMID:28444820 NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO casticin results in increased expression of MUC13 mRNA CTD PMID:27862857 NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO casticin results in increased expression of MYD88 mRNA CTD PMID:27862857 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Myo7a myosin VIIA increases expression ISO casticin results in increased expression of MYO7A mRNA CTD PMID:28444820 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Nanog Nanog homeobox multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of NANOG mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of NANOG protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of NANOG mRNA] CTD PMID:32268151 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO casticin results in decreased expression of NARS mRNA CTD PMID:28444820 NCBI chr18:57,989,308...58,005,639
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO casticin results in decreased expression of NDUFS4 mRNA CTD PMID:28444820 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO casticin results in decreased expression of NFKB1 mRNA CTD PMID:27862857 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO casticin results in decreased expression of NFKB2 mRNA CTD PMID:27862857 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO casticin results in decreased expression of NFKBIA mRNA CTD PMID:27862857 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta decreases expression ISO casticin results in decreased expression of NFKBIB mRNA CTD PMID:27862857 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Nfkbid NFKB inhibitor delta decreases expression ISO casticin results in decreased expression of NFKBID mRNA CTD PMID:27862857 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Nfkbie NFKB inhibitor epsilon decreases expression ISO casticin results in decreased expression of NFKBIE mRNA CTD PMID:27862857 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 increases expression ISO casticin results in increased expression of NFX1 mRNA CTD PMID:28444820 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 increases expression ISO casticin results in increased expression of NKD1 mRNA CTD PMID:27862857 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Nme9 NME/NM23 family member 9 increases expression ISO casticin results in increased expression of NME9 mRNA CTD PMID:28444820 NCBI chr 8:100,013,190...100,034,511 JBrowse link
G Nmt1 N-myristoyltransferase 1 decreases expression ISO casticin results in decreased expression of NMT1 mRNA CTD PMID:28444820 NCBI chr10:87,988,826...88,025,405
Ensembl chr10:87,988,826...88,022,648
JBrowse link
G Nol4l nucleolar protein 4-like decreases expression ISO casticin results in decreased expression of NOL4L mRNA CTD PMID:28444820 NCBI chr 3:141,884,840...142,007,668
Ensembl chr 3:141,884,840...142,008,976
JBrowse link
G Nop58 NOP58 ribonucleoprotein decreases expression ISO casticin results in decreased expression of NOP58 mRNA CTD PMID:28444820 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Npas3 neuronal PAS domain protein 3 decreases expression ISO casticin results in decreased expression of NPAS3 mRNA CTD PMID:28444820 NCBI chr 6:70,702,773...71,527,928 JBrowse link
G Nrg3 neuregulin 3 decreases expression ISO casticin results in decreased expression of NRG3 mRNA CTD PMID:27862857 NCBI chr16:14,229,270...15,352,505 JBrowse link
G Nup205 nucleoporin 205 decreases expression ISO casticin results in decreased expression of NUP205 mRNA CTD PMID:28444820 NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844
JBrowse link
G Nup37 nucleoporin 37 decreases expression ISO casticin results in decreased expression of NUP37 mRNA CTD PMID:28444820 NCBI chr 7:22,556,544...22,609,622
Ensembl chr 7:22,573,764...22,609,616
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 decreases expression ISO casticin results in decreased expression of OLIG2 mRNA CTD PMID:27862857 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152
JBrowse link
G Orc5 origin recognition complex, subunit 5 decreases expression ISO casticin results in decreased expression of ORC5 mRNA CTD PMID:28444820 NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 decreases expression ISO casticin results in decreased expression of OTUB2 mRNA CTD PMID:28444820 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO casticin results in increased expression of P2RX7 mRNA CTD PMID:28444820 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO casticin results in decreased expression of PAIP1 mRNA CTD PMID:28444820 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 decreases expression ISO casticin results in decreased expression of PAK3 mRNA CTD PMID:27862857 NCBI chr  X:107,116,308...107,374,342
Ensembl chr  X:107,260,898...107,368,314
JBrowse link
G Papola poly (A) polymerase alpha decreases expression ISO casticin results in decreased expression of PAPOLA mRNA CTD PMID:28444820 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO casticin results in increased expression of PARP1 protein CTD PMID:32270916 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcdha1 protocadherin alpha 1 increases expression ISO casticin results in increased expression of PCDHA1 mRNA CTD PMID:28444820
G Phf10 PHD finger protein 10 decreases expression ISO casticin results in decreased expression of PHF10 mRNA CTD PMID:28444820 NCBI chr 1:55,952,249...55,968,994
Ensembl chr 1:55,952,253...55,969,038
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression ISO casticin results in decreased expression of PICALM mRNA CTD PMID:28444820 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO casticin results in decreased expression of PLAU protein CTD PMID:28444820 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pmp22 peripheral myelin protein 22 increases expression ISO casticin results in increased expression of PMP22 mRNA CTD PMID:28444820 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
decreases expression
ISO casticin promotes the reaction [MIR148A mRNA results in decreased expression of POU5F1 mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of POU5F1 protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of POU5F1 mRNA] CTD PMID:32268151 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO casticin results in decreased expression of PPARD mRNA CTD PMID:27862857 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO casticin results in increased expression of PPARG mRNA CTD PMID:27862857 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO casticin results in decreased expression of PPARGC1A mRNA CTD PMID:28444820 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 decreases expression ISO casticin results in decreased expression of PPP1R11 mRNA CTD PMID:28444820 NCBI chr20:1,601,350...1,604,857
Ensembl chr20:1,601,346...1,604,846
JBrowse link
G Ppp6r3 protein phosphatase 6, regulatory subunit 3 decreases expression ISO casticin results in decreased expression of PPP6R3 mRNA CTD PMID:28444820 NCBI chr 1:200,693,125...200,807,578
Ensembl chr 1:200,693,440...200,807,548
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression ISO casticin results in decreased expression of PRKAR2B mRNA CTD PMID:27862857 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO casticin results in decreased expression of PRKDC protein CTD PMID:29098808 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prss44 serine protease 44 increases expression ISO casticin results in increased expression of PRSS44 mRNA CTD PMID:28444820 NCBI chr 8:110,791,657...110,805,303
Ensembl chr 8:110,791,698...110,805,303
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO casticin results in decreased expression of PTK2 protein CTD PMID:28444820 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A increases expression ISO casticin results in increased expression of PTPRA mRNA CTD PMID:28444820 NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO casticin results in decreased expression of PTPRD mRNA CTD PMID:28444820 NCBI chr 5:90,046,993...90,698,977
Ensembl chr 5:90,048,966...92,369,396
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression ISO casticin results in decreased expression of PTPRF mRNA CTD PMID:28444820 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Qk quaking decreases expression ISO casticin results in decreased expression of QK mRNA CTD PMID:28444820 NCBI chr 1:50,387,698...50,501,568
Ensembl chr 1:50,387,698...50,498,831
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO casticin results in decreased expression of RAPGEF4 mRNA CTD PMID:28444820 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rars1 arginyl-tRNA synthetase 1 decreases expression ISO casticin results in decreased expression of RARS mRNA CTD PMID:28444820 NCBI chr10:20,270,744...20,295,192
Ensembl chr10:20,270,483...20,295,196
JBrowse link
G Rbmx2 RNA binding motif protein, X-linked 2 decreases expression ISO casticin results in decreased expression of RBMX2 mRNA CTD PMID:28444820 NCBI chr  X:127,888,514...127,896,239
Ensembl chr  X:127,888,438...127,896,869
JBrowse link
G Rcor3 REST corepressor 3 decreases expression ISO casticin results in decreased expression of RCOR3 mRNA CTD PMID:28444820 NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO casticin results in decreased expression of RELA protein CTD PMID:28444820 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rexo2 RNA exonuclease 2 decreases expression ISO casticin results in decreased expression of REXO2 mRNA CTD PMID:28444820 NCBI chr 8:48,811,900...48,823,622
Ensembl chr 8:48,811,900...48,823,622
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO casticin results in decreased expression of RHOA protein CTD PMID:28444820 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rpl22l1 ribosomal protein L22 like 1 decreases expression ISO casticin results in decreased expression of RPL22L1 mRNA CTD PMID:28444820 NCBI chr 2:111,754,687...111,756,623
Ensembl chr 2:111,754,687...111,756,625
JBrowse link
G S100a13 S100 calcium binding protein A13 increases expression ISO casticin results in increased expression of S100A13 mRNA CTD PMID:28444820 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression ISO casticin results in increased expression of SCN1B mRNA CTD PMID:28444820 NCBI chr 1:86,353,917...86,363,836
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression ISO casticin results in increased expression of SLC31A1 mRNA CTD PMID:28444820 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO casticin results in decreased expression of SLC6A9 mRNA CTD PMID:28444820 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Smad1 SMAD family member 1 increases expression ISO casticin results in increased expression of SMAD1 mRNA CTD PMID:27862857 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad3 SMAD family member 3 increases expression ISO casticin results in increased expression of SMAD3 mRNA CTD PMID:27862857 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression ISO casticin results in decreased expression of SNRPG mRNA CTD PMID:28444820 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826
JBrowse link
G Snw1 SNW domain containing 1 decreases expression ISO casticin results in decreased expression of SNW1 mRNA CTD PMID:28444820 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO casticin promotes the reaction [Fluorouracil results in increased expression of SOD1 protein]; Fluorouracil promotes the reaction [casticin results in increased expression of SOD1 protein] CTD PMID:32270916 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO casticin results in decreased expression of SOS1 protein CTD PMID:28444820 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression
increases expression
ISO casticin results in decreased expression of SPARC mRNA
casticin results in increased expression of SPARC mRNA
CTD PMID:27862857 PMID:28444820 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Sparcl1 SPARC like 1 increases expression ISO casticin results in increased expression of SPARCL1 mRNA CTD PMID:28444820 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression ISO casticin results in increased expression of ST13 mRNA CTD PMID:28444820 NCBI chr 7:112,891,007...112,925,727 JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO casticin results in decreased expression of ST3GAL3 mRNA CTD PMID:28444820 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
JBrowse link
G Strbp spermatid perinuclear RNA binding protein decreases expression ISO casticin results in decreased expression of STRBP mRNA CTD PMID:28444820 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
JBrowse link
G Sugp1 SURP and G patch domain containing 1 decreases expression ISO casticin results in decreased expression of SUGP1 mRNA CTD PMID:28444820 NCBI chr16:19,352,659...19,383,533
Ensembl chr16:19,351,793...19,383,756
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO casticin results in decreased expression of SYNCRIP mRNA CTD PMID:28444820 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
JBrowse link
G Syt9 synaptotagmin 9 decreases expression ISO casticin results in decreased expression of SYT9 mRNA CTD PMID:28444820 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007
JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 decreases expression ISO casticin results in decreased expression of TAB2 mRNA CTD PMID:27862857 NCBI chr 1:2,375,026...2,424,759
Ensembl chr 1:2,375,490...2,424,756
JBrowse link
G Tcf7 transcription factor 7 decreases expression ISO casticin results in decreased expression of TCF7 mRNA CTD PMID:28444820 NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression ISO casticin results in decreased expression of THRA mRNA CTD PMID:28444820 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO casticin results in increased expression of TIMP2 mRNA CTD PMID:28444820 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tlk2 tousled-like kinase 2 decreases expression ISO casticin results in decreased expression of TLK2 mRNA CTD PMID:28444820 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO casticin results in decreased expression of TLR4 mRNA CTD PMID:27862857 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tmbim4 transmembrane BAX inhibitor motif containing 4 increases expression ISO casticin results in increased expression of TMBIM4 mRNA CTD PMID:27862857 NCBI chr 7:55,718,690...55,733,277
Ensembl chr 7:55,718,699...55,742,773
JBrowse link
G Tmem45b transmembrane protein 45b increases expression ISO casticin results in increased expression of TMEM45B mRNA CTD PMID:27862857 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453
JBrowse link
G Tmsb10 thymosin, beta 10 increases expression ISO casticin results in increased expression of TMSB10 mRNA CTD PMID:28444820 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO casticin results in increased expression of TNFSF10 protein CTD PMID:27862857 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnpo1 transportin 1 decreases expression ISO casticin results in decreased expression of TNPO1 mRNA CTD PMID:28444820 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Tor1aip2 torsin 1A interacting protein 2 decreases expression ISO casticin results in decreased expression of TOR1AIP2 mRNA CTD PMID:28444820 NCBI chr13:68,225,226...68,256,536
Ensembl chr13:68,230,009...68,256,536
Ensembl chr13:68,230,009...68,256,536
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
ISO casticin results in increased expression of TP53 protein modified form
casticin results in decreased expression of TP53 protein
CTD PMID:29098808 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO casticin results in increased expression of TPI1 mRNA CTD PMID:28444820 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpra1 transmembrane protein adipocyte associated 1 increases expression ISO casticin results in increased expression of TPRA1 mRNA CTD PMID:28444820 NCBI chr 4:121,364,093...121,375,275
Ensembl chr 4:121,364,091...121,375,269
JBrowse link
G Tra2b transformer 2 beta homolog decreases expression ISO casticin results in decreased expression of TRA2B mRNA CTD PMID:28444820 NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249
JBrowse link
G Trap1 TNF receptor-associated protein 1 increases expression ISO casticin results in increased expression of TRAP1 mRNA CTD PMID:27862857 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Trio trio Rho guanine nucleotide exchange factor increases expression ISO casticin results in increased expression of TRIO mRNA CTD PMID:28444820 NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 decreases expression ISO casticin results in decreased expression of UBE2D3 mRNA CTD PMID:28444820 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) decreases expression ISO casticin results in decreased expression of UBE2F mRNA CTD PMID:28444820 NCBI chr 9:91,845,954...91,881,145
Ensembl chr 9:91,845,987...91,880,594
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO casticin results in decreased expression of UBE2W mRNA CTD PMID:28444820 NCBI chr 5:2,690,742...2,754,491 JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO casticin results in decreased expression of VEGFA mRNA CTD PMID:28444820 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vezf1 vascular endothelial zinc finger 1 decreases expression ISO casticin results in decreased expression of VEZF1 mRNA CTD PMID:28444820 NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111
JBrowse link
G Vim vimentin decreases expression
increases expression
ISO casticin results in decreased expression of VIM mRNA
casticin results in increased expression of VIM mRNA
CTD PMID:27862857 PMID:28444820 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO casticin results in decreased expression of VLDLR mRNA CTD PMID:28444820 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Wac WW domain containing adaptor with coiled-coil decreases expression ISO casticin results in decreased expression of WAC mRNA CTD PMID:28444820 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO casticin results in decreased expression of WEE1 protein CTD PMID:29098808 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Wnt5a Wnt family member 5A decreases expression ISO casticin results in decreased expression of WNT5A mRNA CTD PMID:27862857 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression ISO casticin results in decreased expression of WSB1 mRNA CTD PMID:28444820 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
JBrowse link
G Wtap WT1 associated protein decreases expression ISO casticin results in decreased expression of WTAP mRNA CTD PMID:28444820 NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO casticin results in increased expression of XBP1 mRNA CTD PMID:27862857 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO casticin results in decreased expression of XIAP protein CTD PMID:29098808 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta increases expression ISO casticin results in increased expression of YWHAB protein CTD PMID:29098808 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma decreases expression ISO casticin results in decreased expression of YWHAG mRNA CTD PMID:28444820 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Zbtb18 zinc finger and BTB domain containing 18 decreases expression ISO casticin results in decreased expression of ZBTB18 mRNA CTD PMID:28444820 NCBI chr13:89,439,633...89,447,958
Ensembl chr13:89,439,420...89,448,862
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO casticin results in decreased expression of ZFHX4 mRNA CTD PMID:28444820 NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228
JBrowse link
G Zfp384 zinc finger protein 384 decreases expression ISO casticin results in decreased expression of ZFP384 mRNA CTD PMID:28444820 NCBI chr 4:157,810,263...157,840,052
Ensembl chr 4:157,810,352...157,839,766
JBrowse link
G Zfp711 zinc finger protein 711 decreases expression ISO casticin results in decreased expression of ZFP711 mRNA CTD PMID:28444820 NCBI chr  X:77,646,300...77,679,398
Ensembl chr  X:77,646,558...77,678,045
JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO casticin results in decreased expression of ZFR mRNA CTD PMID:28444820 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322
JBrowse link
G Zkscan1 zinc finger with KRAB and SCAN domains 1 increases expression ISO casticin results in increased expression of ZKSCAN1 mRNA CTD PMID:28444820 NCBI chr12:16,966,287...16,987,680
Ensembl chr12:16,966,654...16,983,865
JBrowse link
G Zscan2 zinc finger and SCAN domain containing 2 increases expression ISO casticin results in increased expression of ZSCAN2 mRNA CTD PMID:28444820 NCBI chr 1:134,833,701...134,848,957
Ensembl chr 1:134,833,871...134,848,952
JBrowse link
G Zswim6 zinc finger, SWIM-type containing 6 increases expression ISO casticin results in increased expression of ZSWIM6 mRNA CTD PMID:28444820 NCBI chr 2:39,211,131...39,378,877
Ensembl chr 2:39,212,949...39,378,924
JBrowse link
chrysosplenetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO chrysosplenetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects activity ISO chrysosplenetin affects the activity of CYP3A4 protein CTD PMID:29753067 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      chemical role 19345
        antioxidant 14443
          quercetagetin 283
            3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 0
            3',4',5-trihydroxy-3,6,7-trimethoxyflavone 0
            axillarin 0
            casticin 276
            chrysosplenetin 2
            chrysosplenol C 0
            eupatin 0
            patuletin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  oxacycle 17587
                                    benzopyran 10402
                                      1-benzopyran 10129
                                        flavonoid 6513
                                          flavones 4203
                                            hydroxyflavone 4191
                                              flavonols 4100
                                                7-hydroxyflavonol 4078
                                                  quercetin 4026
                                                    quercetagetin 283
                                                      3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 0
                                                      3',4',5-trihydroxy-3,6,7-trimethoxyflavone 0
                                                      axillarin 0
                                                      casticin 276
                                                      chrysosplenetin 2
                                                      chrysosplenol C 0
                                                      eupatin 0
                                                      patuletin 0
paths to the root