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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ginsenoside Rb2
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Accession:CHEBI:77152 term browser browse the term
Definition:A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.
Synonyms:exact_synonym: (3beta,12beta)-20-{[6-O-(alpha-L-arabinopyranosyl)-beta-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
 related_synonym: (20S)-ginsenoside Rb2;   Formula=C53H90O22;   Ginsenoside C;   InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1;   InChIKey=NODILNFGTFIURN-GZPRDHCNSA-N;   NSC 308878;   SMILES=CC(C)=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]1[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@@H]3CC[C@@]21C
 xref: CAS:11021-13-9;   HMDB:HMDB0034996
 xref_mesh: MESH:C048026
 xref: MetaCyc:CPD-15451;   PMID:21811908;   PMID:21811928;   PMID:22031031;   PMID:22534302;   PMID:22717707;   PMID:23271644;   PMID:23670791;   PMID:23717160;   PMID:24369998;   PMID:8798715;   Patent:WO2006001654;   Reaxys:4901741


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ginsenoside Rb2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP ginsenoside Rb2 results in increased expression of ABCC2 mRNA CTD PMID:23835644 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Lpl lipoprotein lipase increases secretion
decreases secretion
ISO ginsenoside Rb2 results in increased secretion of LPL protein
ginsenoside Rb2 results in decreased secretion of LPL protein
CTD PMID:8988629 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        antimicrobial agent 17312
          antiviral agent 10246
            ginsenoside Rb2 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organochalcogen compound 18856
                                organooxygen compound 18778
                                  carbohydrates and carbohydrate derivatives 12180
                                    carbohydrate 12180
                                      monosaccharide 4023
                                        aldose 2537
                                          aldohexose 2184
                                            glucose 2146
                                              D-glucose 2146
                                                D-glucopyranose 1712
                                                  beta-D-glucose 1603
                                                    beta-D-glucoside 1411
                                                      ginsenoside Rb2 2
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