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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(S)-goitrin
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Accession:CHEBI:80751 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has S-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5S)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (-)-5-vinyl-2-oxazolidinethione;   (5S)-5-ethenyl-2-oxazolidinethione;   (S)-5-ethenyl-2-oxazolidinethione;   (S)-5-vinyloxazolidine-2-thione;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m0/s1;   InChIKey=UZQVYLOFLQICCT-BYPYZUCNSA-N;   L-5-vinyl-2-oxazolidinethione;   L-5-vinyl-2-thiooxazolidone;   L-goitrin;   SMILES=[H][C@@]1(CNC(=S)O1)C=C;   goitrin
 xref: CAS:500-12-9;   Chemspider:5885349;   KEGG:C16817
 xref_mesh: MESH:C004333
 xref: PMID:20551074;   PMID:22023255;   PMID:26946249;   PMID:27022502;   PMID:28894621;   PMID:31918015;   PMID:4100548;   PMID:4122716;   PMID:4177780;   PMID:4185966;   PMID:4186887;   PMID:4187735;   PMID:5038356;   PMID:59353;   PMID:5953555;   PMID:6092032;   PMID:6179840;   PMID:6723906;   PMID:7532609;   PMID:852785;   Patent:CN101445490;   Patent:CN101863850
 cyclic_relationship: is_enantiomer_of CHEBI:183228


show annotations for term's descendants           Sort by:
(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] CTD PMID:7532609 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
goitrin results in decreased expression of GSTP1 protein		 CTD PMID:7532609 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    role 19880
      biological role 19878
        antimicrobial agent 18276
          antiviral agent 11395
            (S)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            organic molecule 19735
                              organic cyclic compound 19528
                                organic heterocyclic compound 18895
                                  organic heteromonocyclic compound 17825
                                    oxazolidines 5451
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (S)-goitrin 2
                                          (RS)-goitrin 2
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