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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:deguelin
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Accession:CHEBI:4357 term browser browse the term
Definition:A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers.
Synonyms:exact_synonym: (7aS,13aS)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
 related_synonym: (-)-cis-deguelin;   (7aS,13aS)-13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one;   (7aS,13aS)-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-7(7aH)-one;   Formula=C23H22O6;   InChI=1S/C23H22O6/c1-23(2)8-7-12-15(29-23)6-5-13-21(24)20-14-9-17(25-3)18(26-4)10-16(14)27-11-19(20)28-22(12)13/h5-10,19-20H,11H2,1-4H3/t19-,20+/m1/s1;   InChIKey=ORDAZKGHSNRHTD-UXHICEINSA-N;   SMILES=[H][C@@]12COC3=C(C=C(OC)C(OC)=C3)[C@]1([H])C(=O)C1=C(O2)C2=C(OC(C)(C)C=C2)C=C1
 xref: CAS:522-17-8;   Chemspider:97058;   HMDB:HMDB0250941;   KEGG:C10417;   KNApSAcK:C00002522;   LINCS:LSM-3368;   LIPID_MAPS_instance:LMPK12060019
 xref_mesh: MESH:C107676
 xref: MetaCyc:CPD-12163;   PMID:27771933;   PMID:28471807;   PMID:29157837;   PMID:30018008;   PMID:30078209;   PMID:30255595;   PMID:30405048;   PMID:30588113;   PMID:30741976;   PMID:30765727;   PMID:30933320;   PMID:31211467;   PMID:31504284;   PMID:31584382;   PMID:31917237;   PMID:32081857;   PMID:32128091;   PMID:32454059;   PMID:32540381;   PMID:33581287;   PMID:33724011;   PMID:34626304;   PMID:34644595;   PMID:9270008;   Wikipedia:Deguelin



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deguelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO deguelin results in increased expression of ABCC4 mRNA CTD PMID:33512557 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 decreases expression ISO deguelin results in decreased expression of ABCC5 mRNA CTD PMID:33512557 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 decreases expression ISO deguelin results in decreased expression of ABCF1 mRNA CTD PMID:33512557 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression ISO deguelin results in decreased expression of ADAM12 mRNA CTD PMID:33512557 NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 decreases expression ISO deguelin results in decreased expression of ADAM8 mRNA CTD PMID:33512557 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adm adrenomedullin multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ADM mRNA] CTD PMID:22745725 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ado 2-aminoethanethiol dioxygenase increases expression ISO deguelin results in increased expression of ADO mRNA CTD PMID:33512557 NCBI chr20:21,044,815...21,045,983
Ensembl chr20:21,044,555...21,049,235
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO deguelin results in increased expression of AEN mRNA CTD PMID:33512557 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO deguelin results in increased expression of and affects the localization of AIFM1 protein CTD PMID:26592500 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akap8l A-kinase anchoring protein 8 like increases expression ISO deguelin results in increased expression of AKAP8L mRNA CTD PMID:33512557 NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases expression ISO deguelin results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO deguelin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 decreases expression ISO deguelin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
affects phosphorylation
increases phosphorylation
multiple interactions
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of AKT1 protein; deguelin results in decreased expression of AKT1 mRNA; deguelin results in decreased expression of AKT1 protein
deguelin affects the phosphorylation of AKT1 protein
deguelin results in increased phosphorylation of AKT1 protein
deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]
deguelin results in decreased phosphorylation of AKT1 protein
CTD PMID:16288123 PMID:17015749 PMID:18593368 PMID:19139008 PMID:19336726 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO deguelin results in decreased expression of ALDH7A1 mRNA CTD PMID:33512557 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO deguelin results in decreased expression of ALDH8A1 mRNA CTD PMID:33512557 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Amdhd2 amidohydrolase domain containing 2 decreases expression ISO deguelin results in decreased expression of AMDHD2 mRNA CTD PMID:33512557 NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
JBrowse link
G Amer1 APC membrane recruitment protein 1 decreases expression ISO deguelin results in decreased expression of AMER1 mRNA CTD PMID:33512557 NCBI chr  X:60,300,595...60,316,480
Ensembl chr  X:60,295,751...60,316,440
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO deguelin results in decreased expression of ANGPTL2 mRNA CTD PMID:33512557 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] CTD PMID:22745725 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anln anillin, actin binding protein increases expression ISO deguelin results in increased expression of ANLN mRNA CTD PMID:33512557 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Ano10 anoctamin 10 decreases expression ISO deguelin results in decreased expression of ANO10 mRNA CTD PMID:33512557 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670
JBrowse link
G Anxa7 annexin A7 increases expression ISO deguelin results in increased expression of ANXA7 mRNA CTD PMID:33512557 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 decreases expression ISO deguelin results in decreased expression of AP2M1 mRNA CTD PMID:33512557 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 decreases expression ISO deguelin results in decreased expression of AP3M1 mRNA CTD PMID:33512557 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO deguelin results in decreased expression of APLP1 mRNA CTD PMID:33512557 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
JBrowse link
G Ar androgen receptor multiple interactions ISO deguelin results in decreased expression of and affects the localization of AR protein CTD PMID:27255535 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO deguelin results in increased expression of ARHGAP8 mRNA CTD PMID:33512557 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO deguelin results in increased expression of ARHGAP9 mRNA CTD PMID:33512557 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO deguelin results in increased expression of ARHGEF2 mRNA CTD PMID:33512557 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Arid4a AT-rich interaction domain 4A decreases expression ISO deguelin results in decreased expression of ARID4A mRNA CTD PMID:33512557 NCBI chr 6:89,522,463...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 increases expression ISO deguelin results in increased expression of ARIH2 mRNA CTD PMID:33512557 NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression ISO deguelin results in increased expression of ARL1 mRNA CTD PMID:33512557 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO deguelin results in increased expression of ARNT mRNA CTD PMID:33512557 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO deguelin results in decreased expression of ARRDC4 mRNA CTD PMID:33512557 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Arsg arylsulfatase G increases expression ISO deguelin results in increased expression of ARSG mRNA CTD PMID:33512557 NCBI chr10:94,412,261...94,551,224
Ensembl chr10:94,447,399...94,542,941
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO deguelin results in increased expression of ASCC3 mRNA CTD PMID:33512557 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO deguelin results in increased expression of ASCL1 mRNA CTD PMID:33512557 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO deguelin results in decreased expression of ASF1B mRNA CTD PMID:33512557 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO deguelin results in decreased expression of ASGR1 mRNA CTD PMID:33512557 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO deguelin results in increased expression of ASNS mRNA CTD PMID:33512557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO deguelin results in increased expression of ASS1 mRNA CTD PMID:33512557 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO deguelin results in increased expression of ATF4 mRNA CTD PMID:33512557 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO deguelin results in increased expression of ATF5 mRNA CTD PMID:33512557 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atg3 autophagy related 3 increases expression ISO deguelin results in increased expression of ATG3 mRNA CTD PMID:33512557 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression ISO deguelin results in increased expression of ATIC mRNA CTD PMID:33512557 NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO deguelin results in decreased expression of ATM mRNA CTD PMID:22227970 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atmin ATM interactor decreases expression ISO deguelin results in decreased expression of ATMIN mRNA CTD PMID:33512557 NCBI chr19:44,996,506...45,013,606
Ensembl chr19:44,996,356...45,013,605
JBrowse link
G Atp11b ATPase phospholipid transporting 11B (putative) decreases expression ISO deguelin results in decreased expression of ATP11B mRNA CTD PMID:33512557 NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
JBrowse link
G Atp11c ATPase phospholipid transporting 11C decreases expression ISO deguelin results in decreased expression of ATP11C mRNA CTD PMID:33512557 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 decreases expression ISO deguelin results in decreased expression of ATP6V0E1 mRNA CTD PMID:33512557 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO deguelin results in decreased expression of ATP6V1B2 mRNA CTD PMID:33512557 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO deguelin results in decreased expression of ATR mRNA CTD PMID:22227970 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor increases expression ISO deguelin results in increased expression of ATRAID mRNA CTD PMID:33512557 NCBI chr 6:25,315,236...25,319,804 JBrowse link
G Aurka aurora kinase A increases expression ISO deguelin results in increased expression of AURKA mRNA CTD PMID:33512557 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G B2m beta-2 microglobulin increases expression ISO deguelin results in increased expression of B2M mRNA CTD PMID:33512557 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 decreases expression ISO deguelin results in decreased expression of B3GALT6 mRNA CTD PMID:33512557 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338
JBrowse link
G B3gat1 beta-1,3-glucuronyltransferase 1 decreases expression ISO deguelin results in decreased expression of B3GAT1 mRNA CTD PMID:33512557 NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO deguelin results in increased expression of BAG3 mRNA CTD PMID:33512557 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO deguelin results in increased expression of BAK1 protein CTD PMID:26592500 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO deguelin results in increased expression of BAX mRNA; deguelin results in increased expression of BAX protein CTD PMID:26592500 PMID:29512685 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO deguelin results in increased expression of BCAT1 mRNA CTD PMID:33512557 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO deguelin results in decreased expression of BCL2 mRNA; deguelin results in decreased expression of BCL2 protein
deguelin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]
CTD PMID:19365708 PMID:22623043 PMID:26592500 PMID:29512685 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]
deguelin results in decreased expression of BCL2L1 mRNA; deguelin results in decreased expression of BCL2L1 protein
CTD PMID:19365708 PMID:21472727 PMID:22623043 PMID:26592500 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression ISO deguelin results in decreased expression of BCL2L11 mRNA CTD PMID:33512557 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l13 BCL2 like 13 decreases expression ISO deguelin results in decreased expression of BCL2L13 mRNA CTD PMID:33512557 NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression ISO deguelin results in decreased expression of BCL2L2 mRNA CTD PMID:33512557 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO deguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]
deguelin results in increased expression of BDNF mRNA
CTD PMID:17209049 PMID:33512557 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO deguelin results in decreased expression of BID mRNA CTD PMID:33512557 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
decreases expression
ISO deguelin inhibits the reaction [docetaxel results in increased expression of BIRC5 protein]; deguelin inhibits the reaction [Doxorubicin results in increased expression of BIRC5 protein]
deguelin results in increased expression of BIRC5 mRNA
deguelin results in decreased expression of BIRC5 protein
CTD PMID:17035597 PMID:18593368 PMID:21472727 PMID:33512557 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 increases expression ISO deguelin results in increased expression of BLOC1S2 mRNA CTD PMID:33512557 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO deguelin results in decreased expression of BMF mRNA CTD PMID:33512557 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO deguelin results in increased expression of BNIP3L mRNA CTD PMID:33512557 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bphl biphenyl hydrolase like decreases expression ISO deguelin results in decreased expression of BPHL mRNA CTD PMID:33512557 NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO deguelin results in decreased expression of BRCA1 mRNA CTD PMID:22227970 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brd2 bromodomain containing 2 increases expression ISO deguelin results in increased expression of BRD2 mRNA CTD PMID:33512557 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Brd3 bromodomain containing 3 decreases expression ISO deguelin results in decreased expression of BRD3 mRNA CTD PMID:33512557 NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
JBrowse link
G Brms1l BRMS1 like transcriptional repressor decreases expression ISO deguelin results in decreased expression of BRMS1L mRNA CTD PMID:33512557 NCBI chr 6:73,266,673...73,300,631
Ensembl chr 6:73,266,691...73,300,631
JBrowse link
G Bsg basigin (Ok blood group) increases expression ISO deguelin results in increased expression of BSG mRNA CTD PMID:33512557 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO deguelin results in increased expression of BTG3 mRNA CTD PMID:33512557 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 decreases expression ISO deguelin results in decreased expression of BZW1 mRNA CTD PMID:33512557 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
JBrowse link
G C1s complement C1s decreases expression ISO deguelin results in decreased expression of C1S mRNA CTD PMID:33512557 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd5 C2 calcium-dependent domain containing 5 decreases expression ISO deguelin results in decreased expression of C2CD5 mRNA CTD PMID:33512557 NCBI chr 4:175,969,544...176,055,597
Ensembl chr 4:175,969,545...176,055,558
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA] CTD PMID:22745725 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 decreases expression ISO deguelin results in decreased expression of CALCOCO1 mRNA CTD PMID:33512557 NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO deguelin results in decreased expression of CALM1 mRNA CTD PMID:33512557 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO deguelin results in decreased expression of CALM3 mRNA CTD PMID:33512557 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Calr calreticulin decreases expression ISO deguelin results in decreased expression of CALR mRNA CTD PMID:33512557 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Calu calumenin decreases expression ISO deguelin results in decreased expression of CALU mRNA CTD PMID:33512557 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO deguelin results in decreased expression of CAMK2B mRNA CTD PMID:33512557 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cant1 calcium activated nucleotidase 1 decreases expression ISO deguelin results in decreased expression of CANT1 mRNA CTD PMID:33512557 NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
JBrowse link
G Canx calnexin increases expression ISO deguelin results in increased expression of CANX mRNA CTD PMID:33512557 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Capn1 calpain 1 decreases expression ISO deguelin results in decreased expression of CAPN1 mRNA CTD PMID:33512557 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Caps calcyphosine decreases expression ISO deguelin results in decreased expression of CAPS mRNA CTD PMID:33512557 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO deguelin results in decreased expression of CARMIL1 mRNA CTD PMID:33512557 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO deguelin results in increased expression of CARS1 mRNA CTD PMID:33512557 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase increases expression ISO deguelin results in increased expression of CASK mRNA CTD PMID:33512557 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
ISO deguelin results in increased cleavage of CASP3 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein
deguelin results in increased activity of CASP3 protein
CTD PMID:18593368 PMID:19336726 PMID:22623043 PMID:22986522 PMID:25242579 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein CTD PMID:25242579 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression ISO deguelin metabolite results in increased expression of CASP7 protein modified form; deguelin results in increased expression of CASP7 protein modified form CTD PMID:19139008 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein CTD PMID:25242579 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cast calpastatin decreases expression ISO deguelin results in decreased expression of CAST mRNA CTD PMID:33512557 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression ISO deguelin results in decreased expression of CBLB mRNA CTD PMID:33512557 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Cbx4 chromobox 4 increases expression ISO deguelin results in increased expression of CBX4 mRNA CTD PMID:33512557 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP deguelin promotes the reaction [Oxygen deficiency results in increased expression of CCL2 mRNA] CTD PMID:22745725 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:28529457 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl9 chemokine (C-C motif) ligand 9 decreases expression ISO deguelin results in decreased expression of CCL15 mRNA CTD PMID:33512557 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccna2 cyclin A2 increases expression ISO deguelin results in increased expression of CCNA2 mRNA CTD PMID:33512557 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO deguelin results in increased expression of CCNB1 mRNA CTD PMID:33512557 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO deguelin results in increased expression of CCNB2 mRNA CTD PMID:33512557 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of CCND1 protein] CTD PMID:15960896 PMID:17015749 PMID:19861542 PMID:21472727 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO deguelin results in decreased expression of CCND3 mRNA CTD PMID:33512557 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO deguelin results in decreased expression of CCNE1 mRNA CTD PMID:29512685 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO deguelin results in decreased expression of CCNE2 mRNA CTD PMID:33512557 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng1 cyclin G1 increases expression ISO deguelin results in increased expression of CCNG1 mRNA CTD PMID:33512557 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccnh cyclin H increases expression ISO deguelin results in increased expression of CCNH mRNA CTD PMID:33512557 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression ISO deguelin results in increased expression of CCT6A mRNA CTD PMID:33512557 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein CTD PMID:25242579 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd163 CD163 molecule multiple interactions EXP [deguelin co-treated with Oxygen deficiency] results in increased expression of CD163 mRNA CTD PMID:22745725 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd19 CD19 molecule decreases expression ISO deguelin results in decreased expression of CD19 mRNA CTD PMID:33512557 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Cd24 CD24 molecule decreases expression ISO deguelin results in decreased expression of CD24 mRNA CTD PMID:33512557 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO deguelin results in decreased expression of CD44 mRNA; deguelin results in decreased expression of CD44 protein CTD PMID:26884827 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO deguelin results in decreased expression of CDC45 mRNA CTD PMID:33512557 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdh1 cadherin 1 multiple interactions
affects localization
increases expression
ISO deguelin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein]
deguelin affects the localization of CDH1 protein
deguelin results in increased expression of CDH1 mRNA; deguelin results in increased expression of CDH1 protein
CTD PMID:22986522 PMID:28509438 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh10 cadherin 10 decreases expression ISO deguelin results in decreased expression of CDH10 mRNA CTD PMID:33512557 NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO deguelin results in decreased expression of CDH2 mRNA; deguelin results in decreased expression of CDH2 protein CTD PMID:22986522 PMID:33512557 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh3 cadherin 3 increases expression ISO deguelin results in increased expression of CDH3 mRNA CTD PMID:19861542 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084
JBrowse link
G Cdh7 cadherin 7 increases expression ISO deguelin results in increased expression of CDH7 mRNA CTD PMID:19861542 NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
JBrowse link
G Cdh9 cadherin 9 increases expression ISO deguelin results in increased expression of CDH9 mRNA CTD PMID:19861542 NCBI chr 2:66,280,422...66,367,121
Ensembl chr 2:66,228,117...66,367,121
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression ISO deguelin results in increased expression of CDK1 mRNA CTD PMID:33512557 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO deguelin metabolite results in decreased expression of CDK4 protein; deguelin results in decreased expression of CDK4 protein CTD PMID:19139008 PMID:19336726 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO deguelin results in decreased expression of CDK5 mRNA CTD PMID:33512557 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 decreases expression ISO deguelin results in decreased expression of CDK5R1 mRNA CTD PMID:33512557 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO deguelin results in increased expression of CDK6 mRNA CTD PMID:33512557 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; deguelin metabolite results in decreased expression of CDKN1A protein; deguelin results in decreased expression of CDKN1A protein
deguelin results in increased expression of CDKN1A mRNA
CTD PMID:19139008 PMID:25242579 PMID:29512685 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO deguelin results in increased expression of CDKN1B mRNA CTD PMID:33512557 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO deguelin results in increased expression of CDKN3 mRNA CTD PMID:33512557 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO deguelin results in increased expression of CDT1 mRNA CTD PMID:33512557 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein CTD PMID:25242579 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO deguelin results in increased expression of CEBPB mRNA CTD PMID:33512557 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cel carboxyl ester lipase decreases expression ISO deguelin results in decreased expression of CEL mRNA CTD PMID:33512557 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO deguelin results in decreased expression of CEMIP2 mRNA CTD PMID:33512557 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Cenpf centromere protein F increases expression ISO deguelin results in increased expression of CENPF mRNA CTD PMID:33512557 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpk centromere protein K decreases expression ISO deguelin results in decreased expression of CENPK mRNA CTD PMID:33512557 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Cenpu centromere protein U increases expression ISO deguelin results in increased expression of CENPU mRNA CTD PMID:33512557 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
JBrowse link
G Cep55 centrosomal protein 55 increases expression ISO deguelin results in increased expression of CEP55 mRNA CTD PMID:33512557 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Cetn3 centrin 3 decreases expression ISO deguelin results in decreased expression of CETN3 mRNA CTD PMID:33512557 NCBI chr 2:12,089,025...12,101,828
Ensembl chr 2:12,089,226...12,101,828
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]
deguelin results in decreased expression of CFLAR mRNA
CTD PMID:22623043 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO deguelin results in increased expression of CHAC1 mRNA CTD PMID:33512557 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO deguelin results in increased expression of CHEK1 mRNA CTD PMID:33512557 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chka choline kinase alpha increases expression ISO deguelin results in increased expression of CHKA mRNA CTD PMID:33512557 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chn1 chimerin 1 increases expression ISO deguelin results in increased expression of CHN1 mRNA CTD PMID:33512557 NCBI chr 3:58,509,822...58,676,774
Ensembl chr 3:58,510,536...58,676,490
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO deguelin results in decreased expression of CHRNA4 mRNA CTD PMID:33512557 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression ISO deguelin results in decreased expression of CHRNB2 mRNA CTD PMID:33512557 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression ISO deguelin results in increased expression of CHUK mRNA CTD PMID:33512557 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression ISO deguelin results in increased expression of CISD1 mRNA CTD PMID:33512557 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression ISO deguelin results in increased expression of CKS1B mRNA CTD PMID:33512557 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO deguelin results in increased expression of CKS2 mRNA CTD PMID:33512557 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn2 claudin 2 increases expression ISO deguelin results in increased expression of CLDN2 mRNA CTD PMID:19861542 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn5 claudin 5 increases expression
decreases expression
ISO deguelin results in increased expression of CLDN5 mRNA
deguelin results in decreased expression of CLDN5 mRNA
CTD PMID:19861542 PMID:33512557 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO deguelin results in increased expression of CLIC4 mRNA CTD PMID:33512557 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO deguelin results in increased expression of CLK1 mRNA CTD PMID:33512557 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO deguelin results in increased expression of CLPX mRNA CTD PMID:33512557 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Cltc clathrin heavy chain increases expression ISO deguelin results in increased expression of CLTC mRNA CTD PMID:33512557 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cmss1 cms1 ribosomal small subunit homolog increases expression ISO deguelin results in increased expression of CMSS1 mRNA CTD PMID:33512557 NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624
JBrowse link
G Cntn1 contactin 1 decreases expression ISO deguelin results in decreased expression of CNTN1 mRNA CTD PMID:33512557 NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
JBrowse link
G Coa6 cytochrome c oxidase assembly factor 6 increases expression ISO deguelin results in increased expression of COA6 mRNA CTD PMID:33512557 NCBI chr19:54,395,682...54,398,918
Ensembl chr19:54,395,742...54,399,407
JBrowse link
G Col4a2 collagen type IV alpha 2 chain increases expression ISO deguelin results in increased expression of COL4A2 mRNA CTD PMID:33512557 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO deguelin results in increased expression of COMT mRNA CTD PMID:33512557 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cops5 COP9 signalosome subunit 5 decreases expression ISO deguelin results in decreased expression of COPS5 mRNA CTD PMID:33512557 NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731
JBrowse link
G Coro1a coronin 1A decreases expression ISO deguelin results in decreased expression of CORO1A mRNA CTD PMID:33512557 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Cpne3 copine 3 decreases expression ISO deguelin results in decreased expression of CPNE3 mRNA CTD PMID:33512557 NCBI chr 5:33,014,658...33,064,004
Ensembl chr 5:33,016,307...33,063,934
JBrowse link
G Cramp1 cramped chromatin regulator homolog 1 decreases expression ISO deguelin results in decreased expression of CRAMP1 mRNA CTD PMID:33512557 NCBI chr10:13,983,781...14,032,409
Ensembl chr10:13,983,866...14,032,392
JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO deguelin results in increased expression of CREBRF mRNA CTD PMID:33512557 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression ISO deguelin results in decreased expression of CRK mRNA CTD PMID:33512557 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein increases expression ISO deguelin results in increased expression of CRKL mRNA CTD PMID:33512557 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases expression ISO deguelin results in decreased expression of CSNK1A1 mRNA CTD PMID:33512557 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO deguelin results in increased expression of CSRNP1 mRNA CTD PMID:33512557 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO deguelin results in increased expression of CTH mRNA CTD PMID:33512557 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO deguelin results in increased expression of CTNNAL1 mRNA CTD PMID:33512557 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression
increases degradation
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein]
deguelin results in decreased expression of CTNNB1 mRNA; deguelin results in decreased expression of CTNNB1 protein
CTD PMID:21472727 PMID:22986522 PMID:33512557 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 decreases expression ISO deguelin results in decreased expression of CTNND1 mRNA CTD PMID:33512557 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO deguelin results in decreased expression of CTPS1 mRNA CTD PMID:33512557 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D increases expression ISO deguelin results in increased expression of CTSD mRNA CTD PMID:33512557 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctss cathepsin S decreases expression ISO deguelin results in decreased expression of CTSS mRNA CTD PMID:33512557 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cttn cortactin decreases expression ISO deguelin results in decreased expression of CTTN mRNA CTD PMID:33512557 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CXCR4 mRNA]
deguelin results in decreased expression of CXCR4 mRNA
CTD PMID:22745725 PMID:33512557 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO deguelin results in decreased expression of CYCS mRNA CTD PMID:33512557 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO deguelin inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA] CTD PMID:19961161 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO deguelin results in decreased expression of CYP26B1 mRNA CTD PMID:33512557 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO deguelin results in decreased expression of DAAM1 mRNA CTD PMID:33512557 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
JBrowse link
G Daxx death-domain associated protein decreases expression ISO deguelin results in decreased expression of DAXX mRNA CTD PMID:33512557 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dbf4 DBF4 zinc finger increases expression ISO deguelin results in increased expression of DBF4 mRNA CTD PMID:33512557 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
JBrowse link
G Dbndd2 dysbindin domain containing 2 decreases expression ISO deguelin results in decreased expression of DBNDD2 mRNA CTD PMID:33512557 NCBI chr 3:153,193,213...153,220,651
Ensembl chr 3:153,191,090...153,220,651
JBrowse link
G Dctd dCMP deaminase increases expression ISO deguelin results in increased expression of DCTD mRNA CTD PMID:33512557 NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446
JBrowse link
G Dcx doublecortin decreases expression ISO deguelin results in decreased expression of DCX mRNA CTD PMID:33512557 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO deguelin results in decreased expression of DDC mRNA CTD PMID:33512557 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO deguelin results in increased expression of DDIT3 mRNA CTD PMID:33512557 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dennd3 DENN domain containing 3 decreases expression ISO deguelin results in decreased expression of DENND3 mRNA CTD PMID:33512557 NCBI chr 7:105,415,870...105,473,583
Ensembl chr 7:105,415,677...105,473,592
JBrowse link
G Depdc1b DEP domain containing 1B increases expression ISO deguelin results in increased expression of DEPDC1B mRNA CTD PMID:33512557 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO deguelin results in decreased expression of DFFB mRNA CTD PMID:33512557 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628
JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit decreases expression ISO deguelin results in decreased expression of DHDDS mRNA CTD PMID:33512557 NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression ISO deguelin results in increased expression of DHRS7 mRNA CTD PMID:33512557 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression ISO deguelin results in increased expression of DHX15 mRNA CTD PMID:33512557 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 decreases expression ISO deguelin results in decreased expression of DKK2 mRNA CTD PMID:19861542 NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO deguelin results in increased expression of DKK4 mRNA CTD PMID:19861542 NCBI chr16:69,402,989...69,406,580
Ensembl chr16:69,402,989...69,406,580
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression ISO deguelin results in increased expression of DLAT mRNA CTD PMID:33512557 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO deguelin results in increased expression of DLGAP5 mRNA CTD PMID:33512557 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dll4 delta like canonical Notch ligand 4 decreases expression ISO deguelin results in decreased expression of DLL4 mRNA CTD PMID:33512557 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO deguelin results in increased expression of DNAJB1 mRNA CTD PMID:33512557 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO deguelin results in increased expression of DNAJB9 mRNA CTD PMID:33512557 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression ISO deguelin results in increased expression of DNAJC15 mRNA CTD PMID:33512557 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
JBrowse link
G Dnm1 dynamin 1 decreases expression ISO deguelin results in decreased expression of DNM1 mRNA CTD PMID:33512557 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnm1l dynamin 1-like increases expression ISO deguelin results in increased expression of DNM1L mRNA CTD PMID:33512557 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dpp10 dipeptidyl peptidase like 10 increases expression ISO deguelin results in increased expression of DPP10 mRNA CTD PMID:33512557 NCBI chr13:34,584,420...36,269,619
Ensembl chr13:34,595,868...36,269,292
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO deguelin results in decreased expression of DRD2 mRNA CTD PMID:33512557 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dusp14 dual specificity phosphatase 14 increases expression ISO deguelin results in increased expression of DUSP14 mRNA CTD PMID:33512557 NCBI chr10:68,936,483...68,966,347
Ensembl chr10:68,935,330...68,965,329
JBrowse link
G Dusp3 dual specificity phosphatase 3 increases expression ISO deguelin results in increased expression of DUSP3 mRNA CTD PMID:33512557 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO deguelin results in increased expression of DUSP4 mRNA CTD PMID:33512557 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 decreases expression ISO deguelin results in decreased expression of DYRK3 mRNA CTD PMID:33512557 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO deguelin results in decreased expression of E2F1 mRNA CTD PMID:33512557 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO deguelin results in decreased expression of EBF1 mRNA CTD PMID:33512557 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 decreases expression ISO deguelin results in decreased expression of EBNA1BP2 mRNA CTD PMID:33512557 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
JBrowse link
G Eea1 early endosome antigen 1 increases expression ISO deguelin results in increased expression of EEA1 mRNA CTD PMID:33512557 NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO deguelin results in increased expression of EEF1B2 mRNA CTD PMID:33512557 NCBI chr 9:64,580,009...64,582,737
Ensembl chr 9:64,579,893...64,582,737
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO deguelin metabolite results in decreased expression of EGFR protein; deguelin results in decreased expression of EGFR protein CTD PMID:19139008 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of EGLN3 mRNA] CTD PMID:22745725 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO deguelin results in increased expression of EIF1 mRNA CTD PMID:33512557 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO deguelin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25322282 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta increases expression ISO deguelin results in increased expression of EIF2S2 mRNA CTD PMID:33512557 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B increases expression ISO deguelin results in increased expression of EIF4B mRNA CTD PMID:33512557 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
increases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of EIF4EBP1 protein modified form; deguelin results in decreased expression of EIF4EBP1 protein modified form
deguelin results in increased expression of EIF4EBP1 mRNA
deguelin results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:19139008 PMID:27255535 PMID:33512557 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 decreases expression ISO deguelin results in decreased expression of ELAVL1 mRNA CTD PMID:33512557 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
JBrowse link
G Elmod1 ELMO domain containing 1 decreases expression ISO deguelin results in decreased expression of ELMOD1 mRNA CTD PMID:33512557 NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO deguelin results in decreased expression of ELP1 mRNA CTD PMID:33512557 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Endog endonuclease G decreases expression ISO deguelin results in decreased expression of ENDOG mRNA CTD PMID:33512557 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Eno2 enolase 2 decreases secretion
decreases expression
ISO deguelin results in decreased secretion of ENO2 protein
deguelin results in decreased expression of ENO2 mRNA
CTD PMID:26884827 PMID:33512557 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein] CTD PMID:27899277 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Ep300 E1A binding protein p300 decreases expression ISO deguelin results in decreased expression of EP300 mRNA CTD PMID:33512557 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,178,529
Ensembl chr 7:113,106,247...113,178,529
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephb2 Eph receptor B2 decreases expression ISO deguelin results in decreased expression of EPHB2 mRNA CTD PMID:33512557 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO deguelin results in increased expression of EPS15 mRNA CTD PMID:33512557 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO deguelin results in decreased expression of ERN1 protein CTD PMID:25322282 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO deguelin results in increased expression of ERO1A mRNA CTD PMID:33512557 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression ISO deguelin results in increased expression of ETF1 mRNA CTD PMID:33512557 NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810
JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO deguelin results in decreased expression of ETNK1 mRNA CTD PMID:33512557 NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression ISO deguelin results in increased expression of ETS1 mRNA CTD PMID:33512557 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Etv1 ETS variant transcription factor 1 decreases expression ISO deguelin results in decreased expression of ETV1 mRNA CTD PMID:33512557 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775
JBrowse link
G Evl Enah/Vasp-like decreases expression ISO deguelin results in decreased expression of EVL mRNA CTD PMID:33512557 NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344
JBrowse link
G Exosc4 exosome component 4 decreases expression ISO deguelin results in decreased expression of EXOSC4 mRNA CTD PMID:33512557 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573
JBrowse link
G Exosc8 exosome component 8 increases expression ISO deguelin results in increased expression of EXOSC8 mRNA CTD PMID:33512557 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Fam174a family with sequence similarity 174, member A decreases expression ISO deguelin results in decreased expression of FAM174A mRNA CTD PMID:33512557 NCBI chr 9:95,742,815...95,761,083
Ensembl chr 9:95,742,927...95,761,081
JBrowse link
G Fam72a family with sequence similarity 72, member A increases expression ISO deguelin results in increased expression of FAM72A mRNA CTD PMID:33512557 NCBI chr13:42,968,409...42,978,976
Ensembl chr13:42,967,578...42,984,208
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO deguelin results in increased expression of FAS mRNA CTD PMID:33512557 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase decreases expression ISO deguelin results in decreased expression of FASN mRNA CTD PMID:33512557 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fastkd5 FAST kinase domains 5 decreases expression ISO deguelin results in decreased expression of FASTKD5 mRNA CTD PMID:33512557 NCBI chr 3:117,830,227...117,847,737
Ensembl chr 3:117,830,083...117,847,820
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO deguelin results in increased expression of FGF2 mRNA CTD PMID:33512557 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO deguelin results in increased expression of FIBIN mRNA CTD PMID:33512557 NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
JBrowse link
G Fig4 FIG4 phosphoinositide 5-phosphatase decreases expression ISO deguelin results in decreased expression of FIG4 mRNA CTD PMID:33512557 NCBI chr20:44,600,603...44,724,047
Ensembl chr20:44,600,603...44,723,844
JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 decreases expression ISO deguelin results in decreased expression of FKBP14 mRNA CTD PMID:33512557 NCBI chr 4:83,705,531...83,721,515
Ensembl chr 4:83,705,652...83,721,528
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO deguelin results in increased expression of FKBP4 mRNA CTD PMID:33512557 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Flna filamin A increases expression ISO deguelin results in increased expression of FLNA mRNA CTD PMID:33512557 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:9270009 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO deguelin results in increased expression of FOSL1 mRNA CTD PMID:33512557 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxj3 forkhead box J3 increases expression ISO deguelin results in increased expression of FOXJ3 mRNA CTD PMID:33512557 NCBI chr 5:133,140,344...133,228,489
Ensembl chr 5:133,140,884...133,228,489
JBrowse link
G Foxo4 forkhead box O4 decreases expression ISO deguelin results in decreased expression of FOXO4 mRNA CTD PMID:33512557 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Frzb frizzled-related protein increases expression ISO deguelin results in increased expression of FRZB mRNA CTD PMID:19861542 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO deguelin results in decreased expression of FSTL1 mRNA CTD PMID:33512557 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO deguelin results in increased expression of FTH1 mRNA CTD PMID:33512557 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO deguelin results in increased expression of FTL mRNA CTD PMID:33512557 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO deguelin results in decreased expression of FYN mRNA CTD PMID:33512557 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Fzd10 frizzled class receptor 10 increases expression ISO deguelin results in increased expression of FZD10 mRNA CTD PMID:19861542 NCBI chr12:28,098,371...28,101,566
Ensembl chr12:28,098,371...28,101,566
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO deguelin results in increased expression of FZD4 mRNA CTD PMID:19861542 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Fzd8 frizzled class receptor 8 increases expression ISO deguelin results in increased expression of FZD8 mRNA CTD PMID:19861542 NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 decreases expression ISO deguelin results in decreased expression of G3BP2 mRNA CTD PMID:33512557 NCBI chr14:15,932,356...16,020,555
Ensembl chr14:15,987,417...16,020,548
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO deguelin results in decreased expression of G6PD mRNA CTD PMID:33512557 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gaa alpha glucosidase decreases expression ISO deguelin results in decreased expression of GAA mRNA CTD PMID:33512557 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gabpb1 GA binding protein transcription factor subunit beta 1 increases expression ISO deguelin results in increased expression of GABPB1 mRNA CTD PMID:33512557 NCBI chr 3:113,879,972...113,924,744
Ensembl chr 3:113,879,973...113,923,696
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO deguelin results in increased expression of GADD45A mRNA CTD PMID:33512557 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression ISO deguelin results in decreased expression of GALE mRNA CTD PMID:33512557 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 decreases expression ISO deguelin results in decreased expression of GALNT3 mRNA CTD PMID:33512557 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO deguelin results in decreased expression of GAP43 mRNA CTD PMID:33512557 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gata2 GATA binding protein 2 increases expression ISO deguelin results in increased expression of GATA2 mRNA CTD PMID:33512557 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO deguelin results in increased expression of GCLC mRNA CTD PMID:33512557 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO deguelin results in increased expression of GCLM mRNA CTD PMID:33512557 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO deguelin results in increased expression of GDF15 mRNA CTD PMID:33512557 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO deguelin results in decreased expression of GINS2 mRNA CTD PMID:33512557 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO deguelin results in decreased expression of GINS3 mRNA CTD PMID:33512557 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO deguelin results in decreased expression of GLDC mRNA CTD PMID:33512557 NCBI chr 1:227,883,247...227,962,119
Ensembl chr 1:227,883,249...227,962,097
JBrowse link
G Gli3 GLI family zinc finger 3 decreases expression ISO deguelin results in decreased expression of GLI3 mRNA CTD PMID:33512557 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Glrx glutaredoxin decreases expression ISO deguelin results in decreased expression of GLRX mRNA CTD PMID:33512557 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gmip Gem-interacting protein decreases expression ISO deguelin results in decreased expression of GMIP mRNA CTD PMID:33512557 NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
JBrowse link
G Gmpr2 guanosine monophosphate reductase 2 decreases expression ISO deguelin results in decreased expression of GMPR2 mRNA CTD PMID:33512557 NCBI chr15:29,165,421...29,175,933
Ensembl chr15:29,165,783...29,174,935
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression ISO deguelin results in decreased expression of GNAI2 mRNA CTD PMID:33512557 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO deguelin results in decreased expression of GNPDA1 mRNA CTD PMID:33512557 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO deguelin results in increased expression of GOT1 mRNA CTD PMID:33512557 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpc1 glypican 1 decreases expression ISO deguelin results in decreased expression of GPC1 mRNA CTD PMID:33512557 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO deguelin results in increased expression of GRB10 mRNA CTD PMID:33512557 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Grb14 growth factor receptor bound protein 14 increases expression ISO deguelin results in increased expression of GRB14 mRNA CTD PMID:33512557 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression ISO deguelin results in decreased expression of GRIA2 mRNA CTD PMID:33512557 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression ISO deguelin results in decreased expression of GRIN2D mRNA CTD PMID:33512557 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grm4 glutamate metabotropic receptor 4 decreases expression ISO deguelin results in decreased expression of GRM4 mRNA CTD PMID:33512557 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grn granulin precursor decreases expression ISO deguelin results in decreased expression of GRN mRNA CTD PMID:33512557 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO deguelin results in decreased phosphorylation of GSK3B protein CTD PMID:19336726 PMID:21472727 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO deguelin results in increased expression of GSR mRNA CTD PMID:33512557 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO deguelin results in decreased expression of GSTM2 mRNA CTD PMID:33512557 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO deguelin results in increased expression of GTF2E2 mRNA CTD PMID:33512557 NCBI chr16:58,399,307...58,449,467
Ensembl chr16:58,399,107...58,449,371
JBrowse link
G Gtpbp8 GTP-binding protein 8 (putative) increases expression ISO deguelin results in increased expression of GTPBP8 mRNA CTD PMID:33512557 NCBI chr11:55,945,778...55,955,743
Ensembl chr11:55,945,795...55,955,635
JBrowse link
G Gucy2c guanylate cyclase 2C decreases expression ISO deguelin results in decreased expression of GUCY2C mRNA CTD PMID:33512557 NCBI chr 4:169,568,505...169,649,092
Ensembl chr 4:169,568,529...169,649,092
JBrowse link
G H1f0 H1.0 linker histone increases expression ISO deguelin results in increased expression of H1-0 mRNA CTD PMID:33512557 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H2az2 H2A.Z variant histone 2 decreases expression ISO deguelin results in decreased expression of H2AZ2 mRNA CTD PMID:33512557 NCBI chr14:81,293,299...81,312,209
Ensembl chr14:81,293,299...81,312,144
JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO deguelin results in increased expression of H2BC12 mRNA CTD PMID:33512557 NCBI chr17:42,485,746...42,486,126 JBrowse link
G Hba-a3 hemoglobin alpha, adult chain 3 increases expression ISO deguelin results in increased expression of HBA2 mRNA CTD PMID:33512557 NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO deguelin results in increased expression of HELLS mRNA CTD PMID:33512557 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO deguelin results in increased expression of HERPUD1 mRNA CTD PMID:33512557 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO deguelin results in increased expression of HES1 mRNA CTD PMID:33512557 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression ISO deguelin results in decreased expression of HEXA mRNA CTD PMID:33512557 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta increases expression ISO deguelin results in increased expression of HEXB mRNA CTD PMID:33512557 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hhip Hedgehog-interacting protein increases expression ISO deguelin results in increased expression of HHIP mRNA CTD PMID:33512557 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases degradation
multiple interactions
ISO deguelin results in increased degradation of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; deguelin metabolite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD PMID:17764071 PMID:18575727 PMID:19139008 PMID:22745725 PMID:27899277 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO deguelin results in increased expression of H2AC8 mRNA CTD PMID:33512557 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H increases expression ISO deguelin results in increased expression of H2AC11 mRNA CTD PMID:33512557 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO deguelin results in increased expression of H2BC5 mRNA CTD PMID:33512557 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO deguelin results in increased expression of HMGA2 mRNA CTD PMID:33512557 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO deguelin results in increased expression of HMMR mRNA CTD PMID:33512557 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO deguelin results in increased expression of HMOX1 mRNA CTD PMID:33512557 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M decreases expression ISO deguelin results in decreased expression of HNRNPM mRNA CTD PMID:33512557 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Homer2 homer scaffold protein 2 decreases expression ISO deguelin results in decreased expression of HOMER2 mRNA CTD PMID:33512557 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO deguelin results in increased expression of HPRT1 mRNA CTD PMID:33512557 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO deguelin results in increased expression of HSD17B11 mRNA CTD PMID:33512557 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 decreases expression ISO deguelin results in decreased expression of HSD17B8 mRNA CTD PMID:33512557 NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO deguelin results in increased expression of HSP90AA1 mRNA CTD PMID:33512557 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression ISO deguelin results in increased expression of HSP90AB1 mRNA CTD PMID:33512557 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO deguelin results in increased expression of HSPA1B mRNA CTD PMID:33512557 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO deguelin results in increased expression of HSPA4 mRNA CTD PMID:33512557 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO deguelin results in increased expression of HSPA8 mRNA CTD PMID:33512557 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO deguelin results in increased expression of HSPB1 mRNA CTD PMID:33512557 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO deguelin results in increased expression of HSPD1 mRNA CTD PMID:33512557 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO deguelin results in increased expression of HSPE1 mRNA CTD PMID:33512557 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO deguelin results in increased expression of HYOU1 mRNA CTD PMID:33512557 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:17015749 PMID:22745725 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO deguelin results in decreased expression of ID1 mRNA CTD PMID:33512557 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression ISO deguelin results in increased expression of IDH3A mRNA CTD PMID:33512557 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO deguelin results in decreased expression of IFI44 mRNA CTD PMID:33512557 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO deguelin results in increased expression of IFI44L mRNA CTD PMID:33512557 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO deguelin results in decreased expression of IFITM2 mRNA CTD PMID:33512557 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 decreases expression ISO deguelin results in decreased expression of IFITM3 mRNA CTD PMID:33512557 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Ifng interferon gamma multiple interactions EXP
ISO
deguelin inhibits the reaction [Perfadex results in increased expression of IFNG protein]
[deguelin co-treated with OVAL protein] results in increased expression of IFNG protein
CTD PMID:22745725 PMID:28529457 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO deguelin results in increased expression of IFRD1 mRNA CTD PMID:33512557 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 increases expression ISO deguelin results in increased expression of IFRD2 mRNA CTD PMID:33512557 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of VEGFA mRNA] CTD PMID:17764071 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO deguelin metabolite results in decreased expression of IGF1R protein; deguelin results in decreased expression of IGF1R mRNA; deguelin results in decreased expression of IGF1R protein CTD PMID:19139008 PMID:33512557 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression ISO deguelin results in decreased expression of IGFBP2 mRNA CTD PMID:33512557 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Ighmbp2 immunoglobulin mu DNA binding protein 2 decreases expression ISO deguelin results in decreased expression of IGHMBP2 mRNA CTD PMID:33512557 NCBI chr 1:200,506,641...200,529,293
Ensembl chr 1:200,506,338...200,529,514
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO deguelin results in increased expression of IHH mRNA CTD PMID:19861542 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Ikbip IKBKB interacting protein increases expression ISO deguelin results in increased expression of IKBIP mRNA CTD PMID:33512557 NCBI chr 7:25,579,759...25,598,548
Ensembl chr 7:25,579,832...25,605,162
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 decreases expression ISO deguelin results in decreased expression of IKZF1 mRNA CTD PMID:33512557 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il10 interleukin 10 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA] CTD PMID:22745725 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of IL13 protein] CTD PMID:28529457 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 multiple interactions EXP
ISO
deguelin inhibits the reaction [Oxygen deficiency results in decreased expression of IL4 mRNA]
deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 mRNA]; deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 protein]
CTD PMID:22745725 PMID:28529457 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of IL5 protein] CTD PMID:28529457 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions EXP deguelin inhibits the reaction [Perfadex results in decreased expression of IL6 protein] CTD PMID:22745725 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression ISO deguelin results in decreased expression of INA mRNA CTD PMID:33512557 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Ipo5 importin 5 increases expression ISO deguelin results in increased expression of IPO5 mRNA CTD PMID:33512557 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO deguelin results in increased expression of IQGAP1 mRNA CTD PMID:33512557 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein CTD PMID:25242579 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 decreases expression ISO deguelin results in decreased expression of ITPR2 mRNA CTD PMID:33512557 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO deguelin results in increased expression of JMJD6 mRNA CTD PMID:33512557 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO deguelin results in increased phosphorylation of JUN protein CTD PMID:25322282 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO deguelin results in decreased expression of JUNB mRNA CTD PMID:33512557 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kat6a lysine acetyltransferase 6A increases expression ISO deguelin results in increased expression of KAT6A mRNA CTD PMID:33512557 NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 increases expression ISO deguelin results in increased expression of KCNJ8 mRNA CTD PMID:33512557 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO deguelin results in decreased expression of KCNK1 mRNA CTD PMID:33512557 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression ISO deguelin results in increased expression of KCTD9 mRNA CTD PMID:33512557 NCBI chr15:41,942,165...41,969,862
Ensembl chr15:41,942,381...41,969,862
JBrowse link
G Kdm5b lysine demethylase 5B decreases expression ISO deguelin results in decreased expression of KDM5B mRNA CTD PMID:33512557 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO deguelin metabolite results in decreased expression of KDR protein; deguelin results in decreased expression of KDR protein CTD PMID:19139008 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO deguelin results in increased expression of KEAP1 mRNA CTD PMID:33512557 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO deguelin results in increased expression of KHDRBS3 mRNA CTD PMID:33512557 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Kif15 kinesin family member 15 increases expression ISO deguelin results in increased expression of KIF15 mRNA CTD PMID:33512557 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO deguelin results in increased expression of KIF20A mRNA CTD PMID:33512557 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif23 kinesin family member 23 increases expression ISO deguelin results in increased expression of KIF23 mRNA CTD PMID:33512557 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C increases expression ISO deguelin results in increased expression of KIF2C mRNA CTD PMID:33512557 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO deguelin results in decreased expression of KIF5C mRNA CTD PMID:33512557 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO deguelin results in decreased expression of KIT mRNA CTD PMID:33512557 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Knl1 kinetochore scaffold 1 increases expression ISO deguelin results in increased expression of KNL1 mRNA CTD PMID:33512557 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Krt17 keratin 17 increases expression ISO deguelin results in increased expression of KRT17 mRNA CTD PMID:33512557 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt18 keratin 18 increases expression
multiple interactions
ISO deguelin results in increased expression of KRT18 protein
deguelin inhibits the reaction [TGFB1 protein results in decreased expression of KRT18 protein]
CTD PMID:22986522 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Ktn1 kinectin 1 increases expression ISO deguelin results in increased expression of KTN1 mRNA CTD PMID:33512557 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
JBrowse link
G L1cam L1 cell adhesion molecule decreases expression ISO deguelin results in decreased expression of L1CAM mRNA CTD PMID:33512557 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lamc2 laminin subunit gamma 2 decreases expression ISO deguelin results in decreased expression of LAMC2 mRNA CTD PMID:33512557 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 decreases expression ISO deguelin results in decreased expression of LAMP1 mRNA CTD PMID:33512557 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression ISO deguelin results in increased expression of LEF1 mRNA CTD PMID:33512557 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lgmn legumain decreases expression ISO deguelin results in decreased expression of LGMN mRNA CTD PMID:33512557 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
JBrowse link
G Lmod1 leiomodin 1 decreases expression ISO deguelin results in decreased expression of LMOD1 mRNA CTD PMID:33512557 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G LOC100125598 metallothionein 1a pseudogene increases expression ISO deguelin results in increased expression of MT1G mRNA CTD PMID:33512557 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G LOC102549061 histone H2B type 1-N-like increases expression ISO deguelin results in increased expression of H2BC3 mRNA CTD PMID:33512557 NCBI chr17:41,380,058...41,380,685 JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like decreases expression ISO deguelin results in decreased expression of CBR1 mRNA CTD PMID:33512557 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO deguelin results in increased expression of H2AC6 mRNA CTD PMID:33512557 NCBI chr17:42,707,863...42,708,420 JBrowse link
G LOC498265 similar to hypothetical protein FLJ10706 decreases expression ISO deguelin results in decreased expression of C1ORF112 mRNA CTD PMID:33512557 NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804
JBrowse link
G LOC684841 similar to CG31613-PA increases expression ISO deguelin results in increased expression of H3C10 mRNA CTD PMID:33512557
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO deguelin results in increased expression of HSPA6 mRNA CTD PMID:33512557 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lox lysyl oxidase multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:22745725 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Loxl1 lysyl oxidase-like 1 decreases expression ISO deguelin results in decreased expression of LOXL1 mRNA CTD PMID:33512557 NCBI chr 8:58,692,592...58,716,356
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lpar2 lysophosphatidic acid receptor 2 decreases expression ISO deguelin results in decreased expression of LPAR2 mRNA CTD PMID:33512557 NCBI chr16:19,592,067...19,600,850
Ensembl chr16:19,595,655...19,599,998
JBrowse link
G Lrp4 LDL receptor related protein 4 increases expression ISO deguelin results in increased expression of LRP4 mRNA CTD PMID:33512557 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO deguelin results in increased expression of LSM2 mRNA CTD PMID:33512557 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266
JBrowse link
G Lss lanosterol synthase decreases expression ISO deguelin results in decreased expression of LSS mRNA CTD PMID:33512557 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 decreases expression ISO deguelin results in decreased expression of MAGI1 mRNA CTD PMID:33512557 NCBI chr 4:126,205,667...126,811,354
Ensembl chr 4:126,206,816...126,811,691
JBrowse link
G Map1b microtubule-associated protein 1B decreases expression ISO deguelin results in decreased expression of MAP1B mRNA CTD PMID:33512557 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO deguelin results in increased expression of MAP1LC3B mRNA CTD PMID:33512557 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO deguelin results in decreased expression of MAP2 mRNA CTD PMID:33512557 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression ISO deguelin metabolite results in decreased expression of MAP2K1 protein; deguelin results in decreased expression of MAP2K1 protein CTD PMID:19139008 PMID:19336726 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO deguelin results in decreased expression of MAP2K2 protein CTD PMID:19336726 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 decreases expression ISO deguelin results in decreased expression of MAP2K7 protein CTD PMID:25322282 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO deguelin affects the expression of MAP3K3 protein CTD PMID:25322282 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Map6 microtubule-associated protein 6 decreases expression ISO deguelin results in decreased expression of MAP6 mRNA CTD PMID:33512557 NCBI chr 1:153,568,019...153,634,415
Ensembl chr 1:153,568,368...153,634,414
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO deguelin affects the phosphorylation of MAPK1 protein CTD PMID:25322282 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 decreases expression ISO deguelin results in decreased expression of MAPK12 mRNA CTD PMID:33512557 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
JBrowse link
G Mapk1ip1l mitogen-activated protein kinase 1 interacting protein 1-like increases expression ISO deguelin results in increased expression of MAPK1IP1L mRNA CTD PMID:33512557 NCBI chr15:20,545,028...20,567,010
Ensembl chr15:20,545,059...20,569,674
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation
decreases expression
ISO deguelin affects the phosphorylation of MAPK3 protein
deguelin results in decreased expression of MAPK3 mRNA
CTD PMID:25322282 PMID:33512557 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 decreases expression ISO deguelin results in decreased expression of MAPRE3 mRNA CTD PMID:33512557 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO deguelin results in decreased expression of MARCKS mRNA CTD PMID:33512557 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO deguelin results in decreased expression of MAT2A mRNA CTD PMID:33512557 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 decreases expression ISO deguelin results in decreased expression of MBTPS1 mRNA CTD PMID:33512557 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO deguelin results in decreased expression of MCL1 protein CTD PMID:21472727 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO deguelin results in decreased expression of MCM3 mRNA CTD PMID:33512557 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 decreases expression ISO deguelin results in decreased expression of MCOLN1 mRNA CTD PMID:33512557 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 increases expression ISO deguelin results in increased expression of MCUR1 mRNA CTD PMID:33512557 NCBI chr17:21,142,526...21,159,651
Ensembl chr17:21,141,602...21,159,651
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO deguelin results in increased expression of MDM2 mRNA CTD PMID:33512557 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me1 malic enzyme 1 increases expression ISO deguelin results in increased expression of ME1 mRNA CTD PMID:33512557 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Me2 malic enzyme 2 increases expression ISO deguelin results in increased expression of ME2 mRNA CTD PMID:33512557 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987
JBrowse link
G Metrn meteorin, glial cell differentiation regulator decreases expression ISO deguelin results in decreased expression of METRN mRNA CTD PMID:33512557 NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
JBrowse link
G Mfsd10 major facilitator superfamily domain containing 10 decreases expression ISO deguelin results in decreased expression of MFSD10 mRNA CTD PMID:33512557 NCBI chr14:76,103,762...76,107,385
Ensembl chr14:76,103,815...76,107,377
JBrowse link
G Mfsd14a major facilitator superfamily domain containing 14A increases expression ISO deguelin results in increased expression of MFSD14A mRNA CTD PMID:33512557 NCBI chr 2:204,579,174...204,611,600
Ensembl chr 2:204,579,174...204,659,319
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO deguelin results in decreased expression of MGMT mRNA CTD PMID:22227970 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO deguelin results in decreased expression of MKI67 protein CTD PMID:22623043 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor decreases expression ISO deguelin results in decreased expression of MLLT11 mRNA CTD PMID:33512557 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO deguelin results in decreased expression of MMP1 protein CTD PMID:25322282 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression ISO deguelin results in decreased expression of MMP13 protein CTD PMID:25322282 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO deguelin results in decreased expression of and results in decreased activity of MMP2 protein
deguelin results in decreased expression of MMP2 mRNA; deguelin results in decreased expression of MMP2 protein
CTD PMID:25322282 PMID:26884827 PMID:33512557 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO deguelin results in decreased expression of MMP7 mRNA CTD PMID:25322282 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases activity
ISO deguelin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
deguelin results in decreased expression of MMP9 mRNA; deguelin results in decreased expression of MMP9 protein
deguelin results in decreased activity of MMP9 protein
CTD PMID:17015749 PMID:25322282 PMID:26884827 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnd1 meiotic nuclear divisions 1 increases expression ISO deguelin results in increased expression of MND1 mRNA CTD PMID:33512557 NCBI chr 2:169,433,538...169,496,081
Ensembl chr 2:169,433,540...169,496,096
JBrowse link
G Morn2 MORN repeat containing 2 decreases expression ISO deguelin results in decreased expression of MORN2 mRNA CTD PMID:33512557 NCBI chr 6:14,718,799...14,725,281 JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP deguelin promotes the reaction [Oxygen deficiency results in increased expression of MRC1 mRNA] CTD PMID:22745725 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 increases expression ISO deguelin results in increased expression of MRPL19 mRNA CTD PMID:33512557 NCBI chr 4:114,521,824...114,526,053
Ensembl chr 4:114,521,824...114,526,053
JBrowse link
G Mrpl58 mitochondrial ribosomal protein L58 increases expression ISO deguelin results in increased expression of MRPL58 mRNA CTD PMID:33512557 NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 decreases expression ISO deguelin results in decreased expression of MRPS6 mRNA CTD PMID:33512557 NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
JBrowse link
G Msh6 mutS homolog 6 increases expression ISO deguelin results in increased expression of MSH6 mRNA CTD PMID:33512557 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msi2 musashi RNA-binding protein 2 decreases expression ISO deguelin results in decreased expression of MSI2 mRNA CTD PMID:33512557 NCBI chr10:73,143,760...73,510,566
Ensembl chr10:73,147,380...73,510,157
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO deguelin results in decreased expression of ND6 mRNA CTD PMID:33512557 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mt2A metallothionein 2A increases expression ISO deguelin results in increased expression of MT2A mRNA CTD PMID:33512557 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtf2 metal response element binding transcription factor 2 increases expression ISO deguelin results in increased expression of MTF2 mRNA CTD PMID:33512557 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 increases expression ISO deguelin results in increased expression of MTHFD1 mRNA CTD PMID:33512557 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO deguelin results in increased expression of MTHFD2 mRNA CTD PMID:33512557 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of MTOR protein; deguelin results in decreased expression of MTOR protein
deguelin results in decreased phosphorylation of MTOR protein
CTD PMID:19139008 PMID:27255535 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO deguelin results in decreased expression of MUC1 mRNA CTD PMID:33512557 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO deguelin inhibits the reaction [OVAL protein results in increased expression of MUC5AC mRNA] CTD PMID:28529457 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Mybl1 MYB proto-oncogene like 1 decreases expression ISO deguelin results in decreased expression of MYBL1 mRNA CTD PMID:33512557 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
decreases expression
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MYC protein]
deguelin results in increased expression of MYC mRNA
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]
CTD PMID:9270009 PMID:17015749 PMID:21472727 PMID:33512557 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myl1 myosin, light chain 1 decreases expression ISO deguelin results in decreased expression of MYL1 mRNA CTD PMID:33512557 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO deguelin results in decreased expression of MYL4 mRNA CTD PMID:33512557 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO deguelin results in increased expression of NAMPT mRNA CTD PMID:33512557 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO deguelin results in decreased expression of NAT1 mRNA CTD PMID:33512557 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nav1 neuron navigator 1 decreases expression ISO deguelin results in decreased expression of NAV1 mRNA CTD PMID:33512557 NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
JBrowse link
G Ncan neurocan decreases expression ISO deguelin results in decreased expression of NCAN mRNA CTD PMID:33512557 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO deguelin results in increased expression of NCAPH mRNA CTD PMID:33512557 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Nck1 NCK adaptor protein 1 increases expression ISO deguelin results in increased expression of NCK1 mRNA CTD PMID:33512557 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 decreases expression ISO deguelin results in decreased expression of NCOA3 mRNA; deguelin results in decreased expression of NCOA3 protein CTD PMID:19365708 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO deguelin results in decreased expression of NDRG1 mRNA CTD PMID:33512557 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression ISO deguelin results in increased expression of NDUFV3 mRNA CTD PMID:33512557 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO deguelin results in decreased expression of NEFH mRNA CTD PMID:33512557 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression ISO deguelin results in decreased expression of NEFL mRNA CTD PMID:33512557 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Neil3 nei-like DNA glycosylase 3 increases expression ISO deguelin results in increased expression of NEIL3 mRNA CTD PMID:33512557 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression
increases expression
ISO deguelin results in decreased expression of NEK2 mRNA; deguelin results in decreased expression of NEK2 protein
deguelin results in increased expression of NEK2 mRNA
CTD PMID:28509438 PMID:33512557 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Neurod1 neuronal differentiation 1 increases expression ISO deguelin results in increased expression of NEUROD1 mRNA CTD PMID:33512557 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649
JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO deguelin results in increased expression of NFE2L1 mRNA CTD PMID:33512557 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
deguelin inhibits the reaction [OVAL protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:17015749 PMID:22623043 PMID:28529457 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nisch nischarin decreases expression ISO deguelin results in decreased expression of NISCH mRNA CTD PMID:33512557 NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression ISO deguelin results in decreased expression of NOLC1 mRNA CTD PMID:33512557 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression ISO deguelin results in increased expression of NOP58 mRNA CTD PMID:33512557 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
ISO deguelin results in decreased expression of NOS2 protein
deguelin inhibits the reaction [OVAL protein results in increased expression of NOS2 mRNA]
CTD PMID:25322282 PMID:28529457 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression ISO deguelin results in decreased expression of NOS3 protein CTD PMID:19336726 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch2 notch receptor 2 increases expression ISO deguelin results in increased expression of NOTCH2 mRNA CTD PMID:33512557 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Notch3 notch receptor 3 decreases expression ISO deguelin results in decreased expression of NOTCH3 mRNA CTD PMID:33512557 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 decreases expression ISO deguelin results in decreased expression of NPDC1 mRNA CTD PMID:33512557 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Npm1 nucleophosmin 1 decreases expression
multiple interactions
increases response to substance
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of TP53 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein
CTD PMID:25242579 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nptx1 neuronal pentraxin 1 decreases expression ISO deguelin results in decreased expression of NPTX1 mRNA CTD PMID:33512557 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO deguelin results in increased expression of NQO1 mRNA CTD PMID:33512557 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO deguelin results in decreased expression of NR2F1 mRNA CTD PMID:33512557 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression ISO deguelin results in increased expression of NR3C1 mRNA CTD PMID:33512557 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO deguelin results in decreased expression of NR4A2 mRNA CTD PMID:33512557 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO deguelin results in decreased expression of NR5A1 mRNA CTD PMID:33512557 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO deguelin results in decreased expression of NRAS mRNA CTD PMID:33512557 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO deguelin results in decreased expression of NRCAM mRNA CTD PMID:33512557 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO deguelin results in increased expression of NRIP1 mRNA CTD PMID:33512557 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nrxn1 neurexin 1 decreases expression ISO deguelin results in decreased expression of NRXN1 mRNA CTD PMID:33512557 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 decreases expression ISO deguelin results in decreased expression of NSG1 mRNA CTD PMID:33512557 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of NT5E protein] CTD PMID:27899277 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression ISO deguelin results in decreased expression of NTRK1 mRNA CTD PMID:33512557 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Nudcd3 NudC domain containing 3 decreases expression ISO deguelin results in decreased expression of NUDCD3 mRNA CTD PMID:33512557 NCBI chr14:80,975,417...81,059,183
Ensembl chr14:80,976,328...81,058,962
JBrowse link
G Nudt5 nudix hydrolase 5 decreases expression ISO deguelin results in decreased expression of NUDT5 mRNA CTD PMID:33512557 NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001
JBrowse link
G Nudt9 nudix hydrolase 9 increases expression ISO deguelin results in increased expression of NUDT9 mRNA CTD PMID:33512557 NCBI chr14:5,675,376...5,693,332
Ensembl chr14:5,675,382...5,693,142
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases expression ISO deguelin results in increased expression of NUF2 mRNA CTD PMID:33512557 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nup85 nucleoporin 85 decreases expression ISO deguelin results in decreased expression of NUP85 mRNA CTD PMID:33512557 NCBI chr10:100,806,482...100,825,029
Ensembl chr10:100,806,437...100,825,043
JBrowse link
G Nup88 nucleoporin 88 decreases expression ISO deguelin results in decreased expression of NUP88 mRNA CTD PMID:33512557 NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
JBrowse link
G Nup98 nucleoporin 98 and 96 precursor decreases expression ISO deguelin results in decreased expression of NUP98 mRNA; deguelin results in decreased expression of NUP98 protein CTD PMID:17490514 NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415
JBrowse link
G Nvl nuclear VCP-like increases expression ISO deguelin results in increased expression of NVL mRNA CTD PMID:33512557 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 increases expression ISO deguelin results in increased expression of OAZ1 mRNA CTD PMID:33512557 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity
multiple interactions
ISO deguelin results in increased activity of ODC1 protein
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
CTD PMID:9270009 PMID:9834970 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Oip5 Opa interacting protein 5 increases expression ISO deguelin results in increased expression of OIP5 mRNA CTD PMID:33512557 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
JBrowse link
G Olfml2b olfactomedin-like 2B decreases expression ISO deguelin results in decreased expression of OLFML2B mRNA CTD PMID:33512557 NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
JBrowse link
G Onecut1 one cut homeobox 1 decreases expression ISO deguelin results in decreased expression of ONECUT1 mRNA CTD PMID:33512557 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277
JBrowse link
G Orc3 origin recognition complex, subunit 3 decreases expression ISO deguelin results in decreased expression of ORC3 mRNA CTD PMID:33512557 NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633
JBrowse link
G Oxa1l OXA1L, mitochondrial inner membrane protein increases expression ISO deguelin results in increased expression of OXA1L mRNA CTD PMID:33512557 NCBI chr15:27,813,688...27,821,319
Ensembl chr15:27,813,625...27,821,319
JBrowse link
G P2rx3 purinergic receptor P2X 3 decreases expression ISO deguelin results in decreased expression of P2RX3 mRNA CTD PMID:33512557 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression ISO deguelin results in increased expression of PAFAH1B1 mRNA CTD PMID:33512557 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
G Pafah1b3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 decreases expression ISO deguelin results in decreased expression of PAFAH1B3 mRNA CTD PMID:33512557 NCBI chr 1:80,881,263...80,883,789
Ensembl chr 1:80,881,309...80,883,893
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO deguelin results in decreased expression of PAIP1 mRNA CTD PMID:33512557 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]
deguelin results in increased cleavage of PARP1 protein
deguelin metabolite results in increased expression of PARP1 protein modified form; deguelin results in increased expression of PARP1 protein modified form
CTD PMID:17015749 PMID:17035597 PMID:19139008 PMID:22986522 PMID:25242579 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 increases expression ISO deguelin results in increased expression of PARP2 mRNA CTD PMID:33512557 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Pbk PDZ binding kinase increases expression ISO deguelin results in increased expression of PBK mRNA CTD PMID:33512557 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pcdha1 protocadherin alpha 1 decreases expression ISO deguelin results in decreased expression of PCDHA1 mRNA CTD PMID:33512557 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha9 protocadherin alpha 9 decreases expression ISO deguelin results in decreased expression of PCDHA9 mRNA CTD PMID:33512557
G Pde1a phosphodiesterase 1A decreases expression ISO deguelin results in decreased expression of PDE1A mRNA CTD PMID:33512557 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pdgfb platelet derived growth factor subunit B decreases expression ISO deguelin results in decreased expression of PDGFB mRNA CTD PMID:33512557 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X increases expression ISO deguelin results in increased expression of PDHX mRNA CTD PMID:33512557 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO deguelin metabolite results in decreased expression of PDK1 protein; deguelin results in decreased expression of PDK1 protein CTD PMID:19139008 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO deguelin results in decreased expression of PEBP1 mRNA CTD PMID:33512557 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Peg10 paternally expressed 10 decreases expression ISO deguelin results in decreased expression of PEG10 mRNA CTD PMID:33512557 NCBI chr 4:32,842,394...32,855,641
Ensembl chr 4:32,848,493...32,852,621
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 decreases expression ISO deguelin results in decreased expression of PFKFB4 mRNA CTD PMID:33512557 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Pfkl phosphofructokinase, liver type decreases expression ISO deguelin results in decreased expression of PFKL mRNA CTD PMID:33512557 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
JBrowse link
G Pga5 pepsinogen A5 increases expression ISO deguelin results in increased expression of PGA5 mRNA CTD PMID:33512557 NCBI chr 1:207,317,021...207,327,156
Ensembl chr 1:207,317,021...207,327,156
JBrowse link
G Pgf placental growth factor decreases expression ISO deguelin results in decreased expression of PGF mRNA CTD PMID:33512557 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO deguelin results in decreased expression of PGK1 mRNA CTD PMID:33512557 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO deguelin results in increased expression of PGM1 mRNA CTD PMID:33512557 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO deguelin results in increased expression of PHGDH mRNA CTD PMID:33512557 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 decreases expression ISO deguelin results in decreased expression of PHLDA1 mRNA CTD PMID:33512557 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha decreases expression ISO deguelin metabolite results in decreased expression of PIK3CA protein; deguelin results in decreased expression of PIK3CA protein CTD PMID:19139008 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO deguelin results in decreased expression of PIK3R3 mRNA CTD PMID:33512557 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583
JBrowse link
G Pink1 PTEN induced kinase 1 decreases expression ISO deguelin results in decreased expression of PINK1 mRNA CTD PMID:33512557 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pip4k2b phosphatidylinositol-5-phosphate 4-kinase type 2 beta decreases expression ISO deguelin results in decreased expression of PIP4K2B mRNA CTD PMID:33512557 NCBI chr10:82,706,016...82,734,938
Ensembl chr10:82,701,098...82,734,938
JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha decreases expression ISO deguelin results in decreased expression of PITPNA mRNA CTD PMID:33512557 NCBI chr10:60,430,712...60,473,564
Ensembl chr10:60,430,748...60,471,342
JBrowse link
G Plcb3 phospholipase C beta 3 decreases expression ISO deguelin results in decreased expression of PLCB3 mRNA CTD PMID:33512557 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO deguelin results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plin2 perilipin 2 increases expression ISO deguelin results in increased expression of PLIN2 mRNA CTD PMID:33512557 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO deguelin results in increased expression of PLP2 mRNA CTD PMID:33512557 NCBI chr  X:14,834,249...14,837,648
Ensembl chr  X:14,834,231...14,838,514
JBrowse link
G Pls1 plastin 1 decreases expression ISO deguelin results in decreased expression of PLS1 mRNA CTD PMID:33512557 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit increases expression ISO deguelin results in increased expression of POLE3 mRNA CTD PMID:33512557 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
JBrowse link
G Polr2e RNA polymerase II, I and III subunit E decreases expression ISO deguelin results in decreased expression of POLR2E mRNA CTD PMID:33512557 NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643
JBrowse link
G Polr2h RNA polymerase II, I and III subunit H increases expression ISO deguelin results in increased expression of POLR2H mRNA CTD PMID:33512557 NCBI chr11:80,192,017...80,197,468
Ensembl chr11:80,192,032...80,197,515
JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit decreases expression ISO deguelin results in decreased expression of POP5 mRNA CTD PMID:33512557 NCBI chr12:41,376,755...41,384,882
Ensembl chr12:41,376,755...41,381,336
JBrowse link
G Pou4f1 POU class 4 homeobox 1 decreases expression ISO deguelin results in decreased expression of POU4F1 mRNA CTD PMID:33512557 NCBI chr15:81,255,566...81,260,057
Ensembl chr15:81,257,781...81,259,728
JBrowse link
G Pou4f2 POU class 4 homeobox 2 decreases expression ISO deguelin results in decreased expression of POU4F2 mRNA CTD PMID:33512557 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO deguelin results in decreased expression of PPARD mRNA CTD PMID:33512557 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Ppie peptidylprolyl isomerase E increases expression ISO deguelin results in increased expression of PPIE mRNA CTD PMID:33512557 NCBI chr 5:135,406,177...135,419,511
Ensembl chr 5:135,406,176...135,419,235
JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 decreases expression ISO deguelin results in decreased expression of PPIL1 mRNA CTD PMID:33512557 NCBI chr20:7,302,292...7,322,349
Ensembl chr20:7,302,621...7,322,354
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta increases expression ISO deguelin results in increased expression of PPP1CB mRNA CTD PMID:33512557 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma increases expression ISO deguelin results in increased expression of PPP1CC mRNA CTD PMID:33512557 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553
JBrowse link
G Ppp1r17 protein phosphatase 1, regulatory subunit 17 decreases expression ISO deguelin results in decreased expression of PPP1R17 mRNA CTD PMID:33512557 NCBI chr 4:85,213,595...85,230,607
Ensembl chr 4:85,213,887...85,230,603
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO deguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein] CTD PMID:17209049 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression ISO deguelin results in decreased expression of PRDX3 mRNA CTD PMID:33512557 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prelid3b PRELI domain containing 3B increases expression ISO deguelin results in increased expression of PRELID3B mRNA CTD PMID:33512557 NCBI chr 3:163,263,059...163,271,055
Ensembl chr 3:163,262,985...163,271,181
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO deguelin results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases expression ISO deguelin results in decreased expression of PRKACA mRNA CTD PMID:33512557 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases expression ISO deguelin results in increased expression of PRKACB mRNA CTD PMID:33512557 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha decreases expression ISO deguelin results in decreased expression of PRKAR1A mRNA CTD PMID:33512557 NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO deguelin results in decreased expression of PRKDC mRNA CTD PMID:22227970 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prmt5 protein arginine methyltransferase 5 increases expression ISO deguelin results in increased expression of PRMT5 mRNA CTD PMID:33512557 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
JBrowse link
G Prr11 proline rich 11 increases expression ISO deguelin results in increased expression of PRR11 mRNA CTD PMID:33512557 NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
JBrowse link
G Prr7 proline rich 7 (synaptic) decreases expression ISO deguelin results in decreased expression of PRR7 mRNA CTD PMID:33512557 NCBI chr17:9,164,375...9,173,669
Ensembl chr17:9,165,269...9,172,536
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO deguelin results in increased expression of PSAT1 mRNA CTD PMID:33512557 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psen1 presenilin 1 increases expression ISO deguelin results in increased expression of PSEN1 mRNA CTD PMID:33512557 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 decreases expression ISO deguelin results in decreased expression of PSEN2 mRNA CTD PMID:33512557 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression ISO deguelin results in increased expression of PSMA1 mRNA CTD PMID:33512557 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psme2 proteasome activator subunit 2 decreases expression ISO deguelin results in decreased expression of PSME2 mRNA CTD PMID:33512557 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
deguelin results in decreased expression of PTGS2 protein
CTD PMID:17015749 PMID:25322282 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression
increases expression
ISO deguelin results in decreased expression of PTK2 protein
deguelin results in increased expression of PTK2 mRNA
CTD PMID:25322282 PMID:33512557 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression ISO deguelin results in decreased expression of PTPRF mRNA CTD PMID:33512557 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Rab31 RAB31, member RAS oncogene family decreases expression ISO deguelin results in decreased expression of RAB31 mRNA CTD PMID:33512557 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta increases expression ISO deguelin results in increased expression of RABGGTB mRNA CTD PMID:33512557 NCBI chr 2:242,844,758...242,850,022
Ensembl chr 2:242,844,762...242,851,050
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO deguelin results in decreased expression of RAC1 protein CTD PMID:26884827 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rad21 RAD21 cohesin complex component increases expression ISO deguelin results in increased expression of RAD21 mRNA CTD PMID:33512557 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO deguelin results in decreased expression of RAD9A mRNA CTD PMID:33512557 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Rala RAS like proto-oncogene A increases expression ISO deguelin results in increased expression of RALA mRNA CTD PMID:33512557 NCBI chr17:47,092,139...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator decreases expression ISO deguelin results in decreased expression of RALGDS mRNA CTD PMID:33512557 NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO deguelin results in increased expression of RARA mRNA CTD PMID:33512557 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO deguelin results in decreased expression of RB1 protein CTD PMID:15960896 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbm12b RNA binding motif protein 12B decreases expression ISO deguelin results in decreased expression of RBM12B mRNA CTD PMID:33512557 NCBI chr 5:25,597,405...25,610,324
Ensembl chr 5:25,590,493...25,611,245
JBrowse link
G Rbm6 RNA binding motif protein 6 increases expression ISO deguelin results in increased expression of RBM6 mRNA CTD PMID:33512557 NCBI chr 8:108,452,687...108,552,783
Ensembl chr 8:108,452,687...108,552,771
JBrowse link
G Rbx1 ring-box 1 decreases expression ISO deguelin results in decreased expression of RBX1 mRNA CTD PMID:33512557 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
decreases phosphorylation
ISO deguelin results in decreased expression of RELA mRNA; deguelin results in decreased expression of RELA protein
deguelin inhibits the reaction [OVAL protein affects the localization of and results in increased phosphorylation of RELA protein]
deguelin results in decreased phosphorylation of RELA protein
deguelin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]
CTD PMID:17015749 PMID:19365708 PMID:22623043 PMID:28529457 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin decreases expression ISO deguelin results in decreased expression of RELN mRNA CTD PMID:33512557 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G RGD1309748 similar to CG4768-PA increases expression ISO deguelin results in increased expression of C16ORF72 mRNA CTD PMID:33512557 NCBI chr10:6,746,037...6,774,992
Ensembl chr10:6,746,048...6,774,992
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO deguelin results in decreased expression of RHOA mRNA; deguelin results in decreased expression of RHOA protein CTD PMID:25322282 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rhob ras homolog family member B decreases expression ISO deguelin results in decreased expression of RHOB mRNA CTD PMID:33512557 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO deguelin results in decreased expression of RNF121 mRNA CTD PMID:33512557 NCBI chr 1:156,377,583...156,439,923
Ensembl chr 1:156,377,364...156,446,826
JBrowse link
G Rnpc3 RNA-binding region (RNP1, RRM) containing 3 decreases expression ISO deguelin results in decreased expression of RNPC3 mRNA CTD PMID:33512557 NCBI chr 2:201,432,769...201,457,015
Ensembl chr 2:201,432,684...201,456,747
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO deguelin results in decreased expression of ROCK1 protein CTD PMID:25322282 PMID:26884827 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rpl11 ribosomal protein L11 increases expression ISO deguelin results in increased expression of RPL11 mRNA CTD PMID:33512557 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl17 ribosomal protein L17 increases expression ISO deguelin results in increased expression of RPL17 mRNA CTD PMID:33512557 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl26 ribosomal protein L26 increases expression ISO deguelin results in increased expression of RPL26 mRNA CTD PMID:33512557 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966
JBrowse link
G Rpl28 ribosomal protein L28 increases expression ISO deguelin results in increased expression of RPL28 mRNA CTD PMID:33512557 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpl3 ribosomal protein L3 increases expression ISO deguelin results in increased expression of RPL3 mRNA CTD PMID:33512557 NCBI chr 7:111,622,257...111,627,639
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl36 ribosomal protein L36 increases expression ISO deguelin results in increased expression of RPL36 mRNA CTD PMID:33512557 NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
JBrowse link
G Rpl4 ribosomal protein L4 increases expression ISO deguelin results in increased expression of RPL4 mRNA CTD PMID:33512557 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpl8 ribosomal protein L8 increases expression ISO deguelin results in increased expression of RPL8 mRNA CTD PMID:33512557 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
JBrowse link
G Rpl9 ribosomal protein L9 increases expression ISO deguelin results in increased expression of RPL9 mRNA CTD PMID:33512557 NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136
JBrowse link
G Rpp40 ribonuclease P/MRP subunit p40 increases expression ISO deguelin results in increased expression of RPP40 mRNA CTD PMID:33512557 NCBI chr17:28,947,730...28,956,790
Ensembl chr17:28,947,734...28,956,788
JBrowse link
G Rps13 ribosomal protein S13 increases expression ISO deguelin results in increased expression of RPS13 mRNA CTD PMID:33512557 NCBI chr 1:170,572,925...170,575,355
Ensembl chr 1:170,572,921...170,575,355
JBrowse link
G Rps18 ribosomal protein S18 increases expression ISO deguelin results in increased expression of RPS18 mRNA CTD PMID:33512557 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps2 ribosomal protein S2 increases expression ISO deguelin results in increased expression of RPS2 mRNA CTD PMID:33512557 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Rps25 ribosomal protein s25 increases expression ISO deguelin results in increased expression of RPS25 mRNA CTD PMID:33512557 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271
JBrowse link
G Rps3 ribosomal protein S3 increases expression ISO deguelin results in increased expression of RPS3 mRNA CTD PMID:33512557 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
JBrowse link
G Rps5 ribosomal protein S5 increases expression ISO deguelin results in increased expression of RPS5 mRNA CTD PMID:33512557 NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
JBrowse link
G Rps6 ribosomal protein S6 decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of RPS6 protein; deguelin metabolite results in decreased expression of RPS6 protein modified form; deguelin results in decreased expression of RPS6 protein; deguelin results in decreased expression of RPS6 protein modified form
deguelin results in decreased phosphorylation of RPS6 protein
CTD PMID:19139008 PMID:27255535 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of RPS6KB1 protein; deguelin results in decreased expression of RPS6KB1 protein
deguelin results in decreased phosphorylation of RPS6KB1 protein
CTD PMID:19139008 PMID:27255535 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO deguelin results in increased expression of RPS7 mRNA CTD PMID:33512557 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
JBrowse link
G Rrp1b ribosomal RNA processing 1B increases expression ISO deguelin results in increased expression of RRP1B mRNA CTD PMID:33512557 NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928
JBrowse link
G Rrp8 ribosomal RNA processing 8 increases expression ISO deguelin results in increased expression of RRP8 mRNA CTD PMID:33512557 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog increases expression ISO deguelin results in increased expression of RRS1 mRNA CTD PMID:33512557 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140
JBrowse link
G Rsl24d1 ribosomal L24 domain containing 1 increases expression ISO deguelin results in increased expression of RSL24D1 mRNA CTD PMID:33512557 NCBI chr 8:73,852,991...73,861,996
Ensembl chr 8:73,852,996...73,862,001
JBrowse link
G Rtn2 reticulon 2 decreases expression ISO deguelin results in decreased expression of RTN2 mRNA CTD PMID:33512557 NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069
JBrowse link
G Rtn4ip1 reticulon 4 interacting protein 1 decreases expression ISO deguelin results in decreased expression of RTN4IP1 mRNA CTD PMID:33512557 NCBI chr20:47,382,251...47,422,747
Ensembl chr20:47,382,234...47,422,338
JBrowse link
G Rxylt1 ribitol xylosyltransferase 1 increases expression ISO deguelin results in increased expression of RXYLT1 mRNA CTD PMID:33512557 NCBI chr 7:57,770,841...57,782,695
Ensembl chr 7:57,770,842...57,782,657
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO deguelin results in decreased expression of SATB1 mRNA CTD PMID:33512557 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Scrn1 secernin 1 decreases expression ISO deguelin results in decreased expression of SCRN1 mRNA CTD PMID:33512557 NCBI chr 4:83,632,125...83,694,225
Ensembl chr 4:83,632,131...83,693,852
JBrowse link
G Sdk2 sidekick cell adhesion molecule 2 decreases expression ISO deguelin results in decreased expression of SDK2 mRNA CTD PMID:33512557 NCBI chr10:98,824,923...99,102,590
Ensembl chr10:98,828,348...99,101,759
JBrowse link
G Sele selectin E multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]
deguelin inhibits the reaction [OVAL protein results in increased expression of SELE mRNA]
CTD PMID:28529457 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sema4b semaphorin 4B decreases expression ISO deguelin results in decreased expression of SEMA4B mRNA CTD PMID:33512557 NCBI chr 1:134,136,646...134,177,777
Ensembl chr 1:134,149,536...134,177,775
JBrowse link
G Senp6 SUMO specific peptidase 6 increases expression ISO deguelin results in increased expression of SENP6 mRNA CTD PMID:33512557 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170
JBrowse link
G Sephs2 selenophosphate synthetase 2 increases expression ISO deguelin results in increased expression of SEPHS2 mRNA CTD PMID:33512557 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
JBrowse link
G Serpinb3 serpin family B member 3 decreases secretion ISO deguelin results in decreased secretion of SERPINB3 protein CTD PMID:26884827 NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682
JBrowse link
G Sesn2 sestrin 2 increases expression ISO deguelin results in increased expression of SESN2 mRNA CTD PMID:33512557 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO deguelin results in decreased expression of SFRP2 mRNA CTD PMID:19861542 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Sgo2 shugoshin 2 increases expression ISO deguelin results in increased expression of SGO2 mRNA CTD PMID:33512557 NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
JBrowse link
G Sh3bgrl3 SH3 domain binding glutamate-rich protein like 3 decreases expression ISO deguelin results in decreased expression of SH3BGRL3 mRNA CTD PMID:33512557 NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 increases expression ISO deguelin results in increased expression of SH3GLB1 mRNA CTD PMID:33512557 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Sirt3 sirtuin 3 decreases expression ISO deguelin results in decreased expression of SIRT3 mRNA CTD PMID:33512557 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 increases expression ISO deguelin results in increased expression of SKA1 mRNA CTD PMID:33512557 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
JBrowse link
G Skp1 S-phase kinase-associated protein 1 decreases expression ISO deguelin results in decreased expression of SKP1 mRNA CTD PMID:33512557 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388
JBrowse link
G Slbp stem-loop binding protein increases expression ISO deguelin results in increased expression of SLBP mRNA CTD PMID:33512557 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression ISO deguelin results in decreased expression of SLC11A2 mRNA CTD PMID:33512557 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc17a6 solute carrier family 17 member 6 decreases expression ISO deguelin results in decreased expression of SLC17A6 mRNA CTD PMID:33512557 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression ISO deguelin results in decreased expression of SLC1A2 mRNA CTD PMID:33512557 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression ISO deguelin results in decreased expression of SLC25A4 mRNA CTD PMID:33512557 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a6 solute carrier family 25 member 6 increases expression ISO deguelin results in increased expression of SLC25A6 mRNA CTD PMID:33512557 NCBI chr18:68,571,229...68,572,474
Ensembl chr18:68,571,300...68,572,199
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO deguelin results in increased expression of SLC2A1 mRNA CTD PMID:33512557 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a6 solute carrier family 2 member 6 decreases expression ISO deguelin results in decreased expression of SLC2A6 mRNA CTD PMID:33512557 NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO deguelin results in increased expression of SLC30A1 mRNA CTD PMID:33512557 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc35a5 solute carrier family 35, member A5 decreases expression ISO deguelin results in decreased expression of SLC35A5 mRNA CTD PMID:33512557 NCBI chr11:55,653,376...55,674,476
Ensembl chr11:55,653,394...55,674,473
JBrowse link
G Slc35f2 solute carrier family 35, member F2 increases expression ISO deguelin results in increased expression of SLC35F2 mRNA CTD PMID:33512557 NCBI chr 8:54,159,970...54,203,614
Ensembl chr 8:54,159,970...54,203,612
JBrowse link
G Slc38a1 solute carrier family 38, member 1 increases expression ISO deguelin results in increased expression of SLC38A1 mRNA CTD PMID:33512557 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO deguelin results in increased expression of SLC3A2 mRNA CTD PMID:33512557 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression ISO deguelin results in decreased expression of SLC6A3 mRNA CTD PMID:33512557 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO deguelin results in increased expression of SLC7A5 mRNA CTD PMID:33512557 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slit2 slit guidance ligand 2 decreases expression ISO deguelin results in decreased expression of SLIT2 mRNA CTD PMID:33512557 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948
JBrowse link
G Slitrk1 SLIT and NTRK-like family, member 1 decreases expression ISO deguelin results in decreased expression of SLITRK1 mRNA CTD PMID:33512557 NCBI chr15:85,723,252...85,727,290
Ensembl chr15:85,724,475...85,727,509
JBrowse link
G Smad3 SMAD family member 3 decreases phosphorylation ISO deguelin results in decreased phosphorylation of SMAD3 protein CTD PMID:22986522 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO deguelin inhibits the reaction [TGFB1 protein affects the localization of SMAD4 protein] CTD PMID:22986522 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smad5 SMAD family member 5 increases expression ISO deguelin results in increased expression of SMAD5 mRNA CTD PMID:33512557 NCBI chr17:7,862,332...7,891,678
Ensembl chr17:7,864,720...7,891,634
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 increases expression ISO deguelin results in increased expression of SMARCC1 mRNA CTD PMID:33512557 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Smc1a structural maintenance of chromosomes 1A decreases expression ISO deguelin results in decreased expression of SMC1A mRNA CTD PMID:33512557 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056
JBrowse link
G Smc3 structural maintenance of chromosomes 3 increases expression ISO deguelin results in increased expression of SMC3 mRNA CTD PMID:33512557 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO deguelin results in increased expression of SMC4 mRNA CTD PMID:33512557 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression
multiple interactions
ISO deguelin results in decreased expression of SNAI1 mRNA; deguelin results in decreased expression of SNAI1 protein
deguelin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]
CTD PMID:19861542 PMID:22986522 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO deguelin results in increased expression of SNAI2 mRNA CTD PMID:33512557 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Snap25 synaptosome associated protein 25 decreases expression ISO deguelin results in decreased expression of SNAP25 mRNA CTD PMID:33512557 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Snca synuclein alpha decreases expression ISO deguelin results in decreased expression of SNCA mRNA CTD PMID:33512557 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression ISO deguelin results in decreased expression of SOCS2 mRNA CTD PMID:33512557 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO deguelin results in decreased expression of SOS1 protein CTD PMID:25322282 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sox14 SRY-box transcription factor 14 increases expression ISO deguelin results in increased expression of SOX14 mRNA CTD PMID:19861542 NCBI chr 8:100,421,982...100,423,918
Ensembl chr 8:100,421,982...100,423,918
JBrowse link
G Sox30 SRY-box transcription factor 30 increases expression ISO deguelin results in increased expression of SOX30 mRNA CTD PMID:19861542 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
JBrowse link
G Sox5 SRY-box transcription factor 5 increases expression ISO deguelin results in increased expression of SOX5 mRNA CTD PMID:19861542 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852
JBrowse link
G Spag5 sperm associated antigen 5 increases expression ISO deguelin results in increased expression of SPAG5 mRNA CTD PMID:33512557 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Spdef SAM pointed domain containing ets transcription factor decreases expression ISO deguelin results in decreased expression of SPDEF mRNA CTD PMID:33512557 NCBI chr20:5,771,434...5,786,793
Ensembl chr20:5,771,441...5,785,893
JBrowse link
G Spopl speckle type BTB/POZ protein like increases expression ISO deguelin results in increased expression of SPOPL mRNA CTD PMID:33512557 NCBI chr 3:6,074,681...6,148,508
Ensembl chr 3:6,078,310...6,108,794
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 increases expression ISO deguelin results in increased expression of SPRED2 mRNA CTD PMID:33512557 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO deguelin results in increased expression of SQSTM1 mRNA CTD PMID:33512557 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases activity ISO deguelin metabolite results in increased activity of SRC protein; deguelin results in increased activity of SRC protein CTD PMID:19139008 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srp72 signal recognition particle 72 increases expression ISO deguelin results in increased expression of SRP72 mRNA CTD PMID:33512557 NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
JBrowse link
G Srsf10 serine and arginine rich splicing factor 10 increases expression ISO deguelin results in increased expression of SRSF10 mRNA CTD PMID:33512557 NCBI chr 5:148,088,765...148,102,964
Ensembl chr 5:148,088,823...148,101,768
JBrowse link
G Ssb small RNA binding exonuclease protection factor La increases expression ISO deguelin results in increased expression of SSB mRNA CTD PMID:33512557 NCBI chr 3:54,616,616...54,626,203
Ensembl chr 3:54,616,619...54,626,203
JBrowse link
G Ssr1 signal sequence receptor subunit 1 decreases expression ISO deguelin results in decreased expression of SSR1 mRNA CTD PMID:33512557 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
JBrowse link
G Sst somatostatin decreases expression ISO deguelin results in decreased expression of SST mRNA CTD PMID:33512557 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases activity ISO deguelin metabolite results in increased activity of STAT3 protein; deguelin results in increased activity of STAT3 protein CTD PMID:19139008 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases phosphorylation ISO deguelin metabolite results in increased phosphorylation of STAT6 protein; deguelin results in increased phosphorylation of STAT6 protein CTD PMID:19139008 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stk25 serine/threonine kinase 25 decreases expression ISO deguelin results in decreased expression of STK25 mRNA CTD PMID:33512557 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244
JBrowse link
G Sts steroid sulfatase multiple interactions ISO deguelin inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Stxbp1 syntaxin binding protein 1 decreases expression ISO deguelin results in decreased expression of STXBP1 mRNA CTD PMID:33512557 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO deguelin results in decreased expression of SULF1 mRNA CTD PMID:33512557 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression ISO deguelin results in decreased expression of SULT1A1 mRNA CTD PMID:33512557 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Supv3l1 Suv3 like RNA helicase increases expression ISO deguelin results in increased expression of SUPV3L1 mRNA CTD PMID:33512557 NCBI chr20:30,378,542...30,399,076
Ensembl chr20:30,378,550...30,399,054
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase decreases expression ISO deguelin results in decreased expression of SUV39H1 mRNA CTD PMID:33512557 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Syp synaptophysin decreases expression ISO deguelin results in decreased expression of SYP mRNA CTD PMID:33512557 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Sypl1 synaptophysin-like 1 increases expression ISO deguelin results in increased expression of SYPL1 mRNA CTD PMID:33512557 NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330
JBrowse link
G Syt1 synaptotagmin 1 decreases expression ISO deguelin results in decreased expression of SYT1 mRNA CTD PMID:33512557 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Sytl1 synaptotagmin-like 1 increases expression ISO deguelin results in increased expression of SYTL1 mRNA CTD PMID:33512557 NCBI chr 5:145,452,524...145,463,114
Ensembl chr 5:145,422,669...145,462,940
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 increases expression ISO deguelin results in increased expression of TACC3 mRNA CTD PMID:33512557 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 increases expression ISO deguelin results in increased expression of TAF7 mRNA CTD PMID:33512557 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 increases expression ISO deguelin results in increased expression of TAF9 mRNA CTD PMID:33512557 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
JBrowse link
G Tagln transgelin increases expression ISO deguelin results in increased expression of TAGLN mRNA CTD PMID:33512557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tapbp TAP binding protein decreases expression ISO deguelin results in decreased expression of TAPBP mRNA CTD PMID:33512557 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181
JBrowse link
G Tbc1d9b TBC1 domain family member 9B decreases expression ISO deguelin results in decreased expression of TBC1D9B mRNA CTD PMID:33512557 NCBI chr10:34,459,931...34,498,431
Ensembl chr10:34,459,953...34,497,145
JBrowse link
G Tbpl1 TATA-box binding protein like 1 increases expression ISO deguelin results in increased expression of TBPL1 mRNA CTD PMID:33512557 NCBI chr 1:22,777,892...22,803,305
Ensembl chr 1:22,778,459...22,803,122
Ensembl chr 1:22,778,459...22,803,122
JBrowse link
G Tcf4 transcription factor 4 increases expression
decreases expression
ISO deguelin results in increased expression of TCF4 mRNA
deguelin results in decreased expression of TCF4 mRNA
CTD PMID:19861542 PMID:33512557 NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
JBrowse link
G Tcta T-cell leukemia translocation altered decreases expression ISO deguelin results in decreased expression of TCTA mRNA CTD PMID:33512557 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564
JBrowse link
G Tctn1 tectonic family member 1 decreases expression ISO deguelin results in decreased expression of TCTN1 mRNA CTD PMID:33512557 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267
JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO deguelin results in decreased expression of TERT mRNA CTD PMID:33512557 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO deguelin results in decreased expression of TFDP1 mRNA CTD PMID:33512557 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
ISO deguelin inhibits the reaction [TGFB1 protein affects the localization of SMAD4 protein]; deguelin inhibits the reaction [TGFB1 protein results in decreased expression of KRT18 protein]; deguelin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; deguelin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]
deguelin results in increased expression of TGFB1 mRNA
CTD PMID:22986522 PMID:33512557 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression ISO deguelin results in decreased expression of TGFB3 mRNA CTD PMID:33512557 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 decreases expression ISO deguelin results in decreased expression of TGFBR2 mRNA CTD PMID:33512557 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO deguelin results in increased expression of TIMP1 protein CTD PMID:25322282 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor