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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-goitrin
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Accession:CHEBI:183228 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5R)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (5R)-5-vinyl-1,3-oxazolidine-2-thione;   (R)-5-ethenyl-2-oxazolidinethione;   (R)-5-vinyl-2-oxazolidinethione;   BA 51-090278;   D-goitrin;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m1/s1;   InChIKey=UZQVYLOFLQICCT-SCSAIBSYSA-N;   SMILES=[H][C@]1(CNC(=S)O1)C=C;   epigoitrin
 xref: CAS:1072-93-1;   Chemspider:2297322;   PMID:11170613;   PMID:17401984;   PMID:19160787;   PMID:23901642;   PMID:25345127;   PMID:26989425;   PMID:27022502;   PMID:27468553;   PMID:28617329;   PMID:28894621;   PMID:30505662;   PMID:30792656;   PMID:31918015;   PMID:32805551;   PMID:33755912;   PMID:34627086;   PMID:7390339
 cyclic_relationship: is_enantiomer_of CHEBI:80751



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(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression
EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] CTD PMID:7532609 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression
EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
goitrin results in decreased expression of GSTP1 protein
CTD PMID:7532609 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        antimicrobial agent 17818
          antiviral agent 10485
            (R)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  organic heteromonocyclic compound 17151
                                    oxazolidines 5491
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (R)-goitrin 2
                                          (RS)-goitrin 2
paths to the root