Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:olomoucine
go back to main search page
Accession:CHEBI:44661 term browser browse the term
Definition:A 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a cyclin-dependent kinase inhibitor.
Synonyms:exact_synonym: 2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethanol
 related_synonym: 2-(2-hydroxyethylamino)-6-(benzylamino)-9-methylpurine;   2-(hydroxyethylamino)-6-benzylamino-9-methylpurine;   2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol;   2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethan-1-ol;   Formula=C15H18N6O;   InChI=1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20);   InChIKey=GTVPOLSIJWJJNY-UHFFFAOYSA-N;   SMILES=CN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO;   olomucine
 xref: CAS:101622-51-9 "ChemIDplus";   DrugBank:DB02116;   FooDB:FDB013890;   HMDB:HMDB0035233;   LINCS:LSM-3857
 xref_mesh: MESH:C090046
 xref: MetaCyc:CPD-5442;   PDBeChem:OLO;   PMID:12147712 "Europe PMC";   PMID:17094472 "Europe PMC";   PMID:18385789 "Europe PMC";   PMID:19723061 "Europe PMC";   PMID:25422646 "Europe PMC";   PMID:27241721 "Europe PMC";   PMID:27345388 "Europe PMC";   PMID:7523194 "Europe PMC";   PMID:7549905 "Europe PMC";   PMID:7925396 "Europe PMC"


show annotations for term's descendants       view all columns           Sort by:
 
olomoucine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tpi1 triosephosphate isomerase 1 JBrowse link 4 157,328,375 157,331,905 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      application 19353
        refrigerant 17254
          ammonia 16703
            organic amino compound 16702
              amino alcohol 869
                ethanolamines 759
                  olomoucine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            organic molecule 19436
                              organic cyclic compound 19199
                                organic heterocyclic compound 18276
                                  organic heteropolycyclic compound 17583
                                    organic heterobicyclic compound 16252
                                      imidazopyrimidine 5424
                                        purines 5422
                                          aminopurine 4378
                                            2,6-diaminopurines 20
                                              olomoucine 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.