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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chrysosplenetin
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Accession:CHEBI:3689 term browser browse the term
Definition:A tetramethoxyflavone that is the 3,6,7,3'-tetramethyl ether derivative of quercetagetin.
Synonyms:exact_synonym: 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one
 related_synonym: Chrysosplenetin B;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-7-9(5-6-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3;   InChIKey=NBVTYGIYKCPHQN-UHFFFAOYSA-N;   Quercetagetin 3,6,7,3'-tetramethyl ether;   SMILES=COc1cc(ccc1O)-c1oc2cc(OC)c(OC)c(O)c2c(=O)c1OC
 xref: CAS:603-56-5;   KEGG:C10030;   KNApSAcK:C00004704;   LIPID_MAPS_instance:LMPK12113009
 xref_mesh: MESH:C570121
 xref: PMID:20506820;   PMID:21914477;   PMID:24422409;   PMID:25335290;   PMID:25898584;   Reaxys:354967;   Wikipedia:Chrysosplenetin


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chrysosplenetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO chrysosplenetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects activity ISO chrysosplenetin affects the activity of CYP3A4 protein CTD PMID:29753067 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      biological role 19849
        antimicrobial agent 18048
          antiviral agent 11013
            chrysosplenetin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic molecule 19721
                              organic cyclic compound 19526
                                organic heterocyclic compound 18864
                                  oxacycle 17785
                                    benzopyran 11728
                                      1-benzopyran 11493
                                        flavonoid 6836
                                          anthoxanthin 4527
                                            flavones 4529
                                              hydroxyflavone 4507
                                                flavonols 4400
                                                  7-hydroxyflavonol 4377
                                                    quercetin 4315
                                                      quercetagetin 282
                                                        chrysosplenetin 2
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