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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:13,14-dihydro-Delta(12)-prostaglandin J2
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Accession:CHEBI:28130 term browser browse the term
Definition:A member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer).
Synonyms:exact_synonym: (5Z,12E,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
 related_synonym: 9-Deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9), delta(12)-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9,12)-13,14-dihydro PGD2;   Dddd-PGD2;   Formula=C20H30O4;   InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24)/b7-4-,18-14+/t16-,17-/m0/s1;   InChIKey=TUXFWOHFPFBNEJ-GJGHEGAFSA-N;   SMILES=CCCCC[C@H](O)C\\C=C1/[C@@H](C\\C=C/CCCC(O)=O)C=CC1=O;   d12-PGJ2;   delta-12-PGJ2;   delta-12-Prostaglandin J2
 alt_id: CHEBI:10537;   CHEBI:23604
 xref: CAS:87893-54-7;   KEGG:C05958;   LIPID_MAPS_instance:LMFA03010020
 xref_mesh: MESH:C040810
 cyclic_relationship: is_conjugate_acid_of CHEBI:133424



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13,14-dihydro-Delta(12)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
EXP 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]
CTD PMID:22982731 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA] CTD PMID:22982731 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      biological role 19711
        antimicrobial agent 17880
          antiviral agent 10711
            13,14-dihydro-Delta(12)-prostaglandin J2 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic acid 18518
                                        monocarboxylic acid 17852
                                          fatty acid 16519
                                            fatty acid derivative 8893
                                              icosanoid 466
                                                prostanoid 403
                                                  prostaglandin 396
                                                    prostaglandins D 144
                                                      prostaglandin D2 144
                                                        prostaglandin J2 128
                                                          13,14-dihydro-Delta(12)-prostaglandin J2 4
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