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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:13,14-dihydro-Delta(12)-prostaglandin J2
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Accession:CHEBI:28130 term browser browse the term
Definition:A member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer).
Synonyms:exact_synonym: (5Z,12E,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
 related_synonym: 9-Deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9), delta(12)-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9,12)-13,14-dihydro PGD2;   Dddd-PGD2;   Formula=C20H30O4;   InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24)/b7-4-,18-14+/t16-,17-/m0/s1;   InChIKey=TUXFWOHFPFBNEJ-GJGHEGAFSA-N;   SMILES=CCCCC[C@H](O)C\\C=C1/[C@@H](C\\C=C/CCCC(O)=O)C=CC1=O;   d12-PGJ2;   delta-12-PGJ2;   delta-12-Prostaglandin J2
 alt_id: CHEBI:10537;   CHEBI:23604
 xref: CAS:87893-54-7;   KEGG:C05958;   LIPID_MAPS_instance:LMFA03010020
 xref_mesh: MESH:C040810
 cyclic_relationship: is_conjugate_acid_of CHEBI:133424


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13,14-dihydro-Delta(12)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions		 EXP 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]		 CTD PMID:22982731 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA] CTD PMID:22982731 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      biological role 19773
        antimicrobial agent 17482
          antiviral agent 10308
            13,14-dihydro-Delta(12)-prostaglandin J2 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic group 18739
                              organic divalent group 18730
                                organodiyl group 18730
                                  carbonyl group 18678
                                    carbonyl compound 18678
                                      carboxylic acid 18376
                                        monocarboxylic acid 17639
                                          fatty acid 16011
                                            fatty acid derivative 1044
                                              icosanoid 457
                                                prostanoid 397
                                                  prostaglandin 392
                                                    prostaglandins D 140
                                                      prostaglandin D2 140
                                                        prostaglandin J2 125
                                                          13,14-dihydro-Delta(12)-prostaglandin J2 4
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