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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:13,14-dihydro-Delta(12)-prostaglandin J2
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Accession:CHEBI:28130 term browser browse the term
Definition:A member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer).
Synonyms:exact_synonym: (5Z,12E,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
 related_synonym: 9-Deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9), delta(12)-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9,12)-13,14-dihydro PGD2;   Dddd-PGD2;   Formula=C20H30O4;   InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24)/b7-4-,18-14+/t16-,17-/m0/s1;   InChIKey=TUXFWOHFPFBNEJ-GJGHEGAFSA-N;   SMILES=CCCCC[C@H](O)C\\C=C1/[C@@H](C\\C=C/CCCC(O)=O)C=CC1=O;   d12-PGJ2;   delta-12-PGJ2;   delta-12-Prostaglandin J2
 alt_id: CHEBI:10537;   CHEBI:23604
 xref: CAS:87893-54-7;   KEGG:C05958;   LIPID_MAPS_instance:LMFA03010020
 xref_mesh: MESH:C040810
 cyclic_relationship: is_conjugate_acid_of CHEBI:133424



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13,14-dihydro-Delta(12)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions
EXP 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]
CTD PMID:22982731 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA] CTD PMID:22982731 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link

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  CHEBI ontology 19848
    role 19824
      biological role 19822
        antimicrobial agent 18193
          antiviral agent 11077
            13,14-dihydro-Delta(12)-prostaglandin J2 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      carbon group element atom 19741
                        carbon atom 19737
                          organic molecular entity 19737
                            heteroorganic entity 19495
                              organochalcogen compound 19257
                                organooxygen compound 19175
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18006
                                        fatty acid 16810
                                          fatty acid derivative 8970
                                            icosanoid 471
                                              prostanoid 407
                                                prostaglandin 399
                                                  prostaglandins D 145
                                                    prostaglandin D2 145
                                                      prostaglandin J2 129
                                                        13,14-dihydro-Delta(12)-prostaglandin J2 4
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