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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:13,14-dihydro-Delta(12)-prostaglandin J2
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Accession:CHEBI:28130 term browser browse the term
Definition:A member of the class of prostaglandins J that is prosta-5,9,12-trien-1-oic acid carrying oxo and hydsroxy substituents at positions 11 and 15 respectively (the 5Z,12E,15S-stereoisomer).
Synonyms:exact_synonym: (5Z,12E,15S)-15-hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid
 related_synonym: 9-Deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9), delta(12)-13,14-dihydroprostaglandin D2;   9-Deoxy-delta(9,12)-13,14-dihydro PGD2;   Dddd-PGD2;   Formula=C20H30O4;   InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24)/b7-4-,18-14+/t16-,17-/m0/s1;   InChIKey=TUXFWOHFPFBNEJ-GJGHEGAFSA-N;   SMILES=CCCCC[C@H](O)C\\C=C1/[C@@H](C\\C=C/CCCC(O)=O)C=CC1=O;   d12-PGJ2;   delta-12-PGJ2;   delta-12-Prostaglandin J2
 alt_id: CHEBI:10537;   CHEBI:23604
 xref: CAS:87893-54-7;   KEGG:C05958;   LIPID_MAPS_instance:LMFA03010020
 xref_mesh: MESH:C040810
 cyclic_relationship: is_conjugate_acid_of CHEBI:133424

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13,14-dihydro-Delta(12)-prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions		 EXP 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]		 CTD PMID:22982731 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP NFE2L2 protein affects the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA] CTD PMID:22982731 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA] CTD PMID:22982731 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        antimicrobial agent 17309
          antiviral agent 10245
            13,14-dihydro-Delta(12)-prostaglandin J2 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          fatty acid 15844
                                            fatty acid derivative 1021
                                              icosanoid 453
                                                prostanoid 395
                                                  prostaglandin 390
                                                    prostaglandins D 139
                                                      prostaglandin D2 139
                                                        prostaglandin J2 125
                                                          13,14-dihydro-Delta(12)-prostaglandin J2 4
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