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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antiviral drug
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Accession:CHEBI:36044 term browser browse the term
Definition:A substance used in the prophylaxis or therapy of virus diseases.
Synonyms:related_synonym: anti-viral drug;   anti-virus drug;   antiviral drugs



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2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]
CTD PMID:31029725 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA; 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein
CTD PMID:31029725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein] CTD PMID:31029725 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA] CTD PMID:31029725 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:31029725 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:31029725 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased phosphorylation of MAPK8 protein
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]
CTD PMID:31029725 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein]
CTD PMID:31029725 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of and affects the stability of NFKBIA protein] CTD PMID:31029725 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]
CTD PMID:31029725 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]
CTD PMID:31029725 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA] CTD PMID:31029725 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
5-iodo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase affects response to substance ISO MBD4 protein affects the susceptibility to Idoxuridine CTD PMID:16885370 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Idoxuridine results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions EXP Idoxuridine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine] CTD PMID:8713072 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
JBrowse link
G Tyms thymidylate synthetase affects uptake ISO TYMS protein affects the uptake of Idoxuridine CTD PMID:15001691 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
abacavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
decreases export
ISO [Estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir; [isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of abacavir]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of abacavir]
CTD PMID:17437964 PMID:19056916 PMID:25844889 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Alb albumin affects binding
multiple interactions
ISO abacavir binds to ALB protein
abacavir inhibits the reaction [Heme binds to ALB protein]; Heme inhibits the reaction [abacavir binds to ALB protein]
CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO abacavir results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Crp C-reactive protein increases expression ISO abacavir results in increased expression of CRP protein CTD PMID:19891054 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO abacavir results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO abacavir results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO abacavir results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO abacavir results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO abacavir results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO abacavir results in increased expression of GFAP protein CTD PMID:19358275 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hoxb7 homeo box B7 increases expression ISO abacavir results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Hoxb9 homeo box B9 increases expression ISO abacavir results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Ifng interferon gamma multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IFNG protein CTD PMID:23541086 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IL13 protein CTD PMID:23541086 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 affects response to substance ISO IL4 protein affects the susceptibility to abacavir CTD PMID:15867870 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO abacavir results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO abacavir results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO abacavir results in increased expression of MMP9 protein CTD PMID:19891054 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase increases expression ISO abacavir results in increased expression of MPO protein CTD PMID:19891054 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO abacavir results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:216,092,709...216,095,276
Ensembl chr 2:216,093,363...216,094,154
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO abacavir results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149
JBrowse link
G Pax3 paired box 3 decreases expression ISO abacavir results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pax6 paired box 6 increases expression ISO abacavir results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pdcd1 programmed cell death 1 multiple interactions ISO [HLA-B protein alternative form results in increased susceptibility to abacavir] which results in increased expression of PDCD1 CTD PMID:34606953 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO [Quinine results in decreased activity of SLC22A1] which results in decreased uptake of abacavir CTD PMID:25844889 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Syp synaptophysin increases expression ISO abacavir results in increased expression of SYP protein CTD PMID:19358275 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO abacavir results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766
JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO abacavir results in decreased activity of TERT protein CTD PMID:19358275 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of TNF protein CTD PMID:23541086 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO abacavir results in increased expression of UCP1 mRNA CTD PMID:14518702 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Uncx UNC homeobox decreases expression ISO abacavir results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:15,092,779...15,097,300
Ensembl chr12:15,092,784...15,097,300
JBrowse link
acyclovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
multiple interactions
ISO ABCG2 protein affects the transport of Acyclovir
tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of Acyclovir]
CTD PMID:21859328 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Aqp2 aquaporin 2 decreases expression EXP Acyclovir results in decreased expression of AQP2 protein CTD PMID:14675048 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Acyclovir inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] CTD PMID:36416909 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Acyclovir inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:36416909 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases activity ISO Acyclovir results in decreased activity of HAAO protein CTD PMID:17174341 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 decreases activity ISO Acyclovir results in decreased activity of IDO1 protein CTD PMID:17174341 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Acyclovir inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] CTD PMID:36416909 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Acyclovir results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Acyclovir results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il24 interleukin 24 increases expression ISO Acyclovir results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Acyclovir affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Acyclovir results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Acyclovir results in decreased expression of SLC12A1 mRNA; Acyclovir results in decreased expression of SLC12A1 protein CTD PMID:14675048 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc17a1 solute carrier family 17 member 1 decreases expression EXP Acyclovir results in decreased expression of SLC17A1 mRNA; Acyclovir results in decreased expression of SLC17A1 protein CTD PMID:14675048 NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Acyclovir results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Acyclovir results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity EXP Acyclovir results in decreased activity of TDO2 protein CTD PMID:18665439 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Acyclovir inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein] CTD PMID:36416909 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
adefovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
affects transport
EXP Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] CTD PMID:21240898 PMID:21341280 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects abundance
multiple interactions
decreases expression
increases export
ISO
EXP
ABCC4 protein affects the abundance of adefovir
[adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] affects the expression of ABCC4 protein; [adefovir co-treated with Probenecid co-treated with Valsartan] affects the expression of ABCC4 protein; [adefovir co-treated with Probenecid] results in decreased expression of ABCC4 protein
adefovir results in decreased expression of ABCC4 protein
ABCC4 protein results in increased export of adefovir
CTD PMID:18364470 PMID:35114312 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
EXP adefovir results in increased expression of ACTA2 protein
[adefovir co-treated with Probenecid] results in increased expression of ACTA2 protein; Cromolyn Sodium inhibits the reaction [[adefovir co-treated with Probenecid] results in increased expression of ACTA2 protein]; Valsartan inhibits the reaction [[adefovir co-treated with Probenecid] results in increased expression of ACTA2 protein]
CTD PMID:35114312 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen multiple interactions EXP [Probenecid co-treated with adefovir] results in increased expression of AGT protein; [Probenecid co-treated with Valsartan co-treated with adefovir] results in increased expression of AGT protein; Cromolyn Sodium inhibits the reaction [[Probenecid co-treated with adefovir] results in increased expression of AGT protein] CTD PMID:35114312 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G B2m beta-2 microglobulin increases secretion EXP adefovir results in increased secretion of B2M protein CTD PMID:27742868 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Calb1 calbindin 1 increases secretion EXP adefovir results in increased secretion of CALB1 protein CTD PMID:27742868 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Cma1 chymase 1 increases secretion EXP adefovir results in increased secretion of CMA1 protein CTD PMID:35114312 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Cst3 cystatin C multiple interactions
increases expression
EXP [adefovir co-treated with Probenecid] results in increased expression of CST3 protein; [Probenecid co-treated with Valsartan co-treated with adefovir] results in increased expression of CST3 protein; [Probenecid co-treated with Valsartan] inhibits the reaction [adefovir results in increased expression of CST3 protein]; Cromolyn Sodium inhibits the reaction [[adefovir co-treated with Probenecid] results in increased expression of CST3 protein] CTD PMID:35114312 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO adefovir results in decreased activity of CYP2C9 protein CTD PMID:17162464 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion EXP adefovir results in increased secretion of HAVCR1 protein CTD PMID:27742868 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Lcn2 lipocalin 2 increases secretion EXP adefovir results in increased secretion of LCN2 protein CTD PMID:27742868 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression
increases expression
ISO adefovir affects the expression of MMUT mRNA mutant form; adefovir affects the expression of MMUT protein mutant form
adefovir results in increased expression of MMUT mRNA; adefovir results in increased expression of MMUT protein
CTD PMID:19199343 PMID:19427250 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
multiple interactions
decreases expression
affects response to substance
increases response to substance
EXP
ISO
SLC22A6 protein results in increased uptake of adefovir
[adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] affects the expression of SLC22A6 protein; [adefovir co-treated with Probenecid co-treated with Valsartan] affects the expression of SLC22A6 protein; [adefovir co-treated with Probenecid] results in decreased expression of SLC22A6 protein; Valsartan inhibits the reaction [[adefovir co-treated with Probenecid] results in decreased expression of SLC22A6 protein]
adefovir results in decreased expression of SLC22A6 protein
SLC22A6 protein affects the susceptibility to adefovir
adefovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to adefovir]; quercetin 3'-sulfate inhibits the reaction [SLC22A6 protein affects the susceptibility to adefovir]; SLC22A6 protein results in increased uptake of and results in increased susceptibility to adefovir
CTD PMID:16857889 PMID:21244849 PMID:23856525 PMID:25448811 PMID:35114312 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance
multiple interactions
decreases expression
ISO
EXP
SLC22A8 protein results in increased susceptibility to adefovir
[adefovir co-treated with Probenecid co-treated with Cromolyn Sodium] results in increased expression of SLC22A8 protein; [adefovir co-treated with Probenecid co-treated with Valsartan] results in increased expression of SLC22A8 protein; [adefovir co-treated with Probenecid] results in decreased expression of SLC22A8 protein; Cromolyn Sodium inhibits the reaction [[adefovir co-treated with Probenecid] results in decreased expression of SLC22A8 protein]
adefovir results in decreased expression of SLC22A8 protein
CTD PMID:25448811 PMID:35114312 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Spp1 secreted phosphoprotein 1 increases secretion EXP adefovir results in increased secretion of SPP1 protein CTD PMID:27742868 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
EXP adefovir results in increased expression of TGFB1 protein
[adefovir co-treated with Probenecid] results in increased expression of TGFB1 protein; Cromolyn Sodium inhibits the reaction [[adefovir co-treated with Probenecid] results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [[adefovir co-treated with Probenecid] results in increased expression of TGFB1 protein]
CTD PMID:35114312 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
adefovir pivoxil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects activity ISO adefovir dipivoxil affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO adefovir dipivoxil results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO adefovir dipivoxil results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO adefovir dipivoxil results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO adefovir dipivoxil results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO adefovir dipivoxil results in increased expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO adefovir dipivoxil results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO adefovir dipivoxil results in decreased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO adefovir dipivoxil results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO adefovir dipivoxil results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Aurkb aurora kinase B increases expression ISO adefovir dipivoxil results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO adefovir dipivoxil results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO adefovir dipivoxil results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member increases expression ISO adefovir dipivoxil results in increased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO adefovir dipivoxil results in decreased expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO adefovir dipivoxil results in decreased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO adefovir dipivoxil results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Ccne2 cyclin E2 increases expression ISO adefovir dipivoxil results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO adefovir dipivoxil results in increased expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO adefovir dipivoxil results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO adefovir dipivoxil results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Coch cochlin increases expression ISO adefovir dipivoxil results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO adefovir dipivoxil results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO adefovir dipivoxil results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctsc cathepsin C decreases expression ISO adefovir dipivoxil results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO adefovir dipivoxil results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO adefovir dipivoxil results in decreased activity of CYP2C9 protein CTD PMID:17162464 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO adefovir dipivoxil results in decreased activity of CYP3A4 protein CTD PMID:17162464 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO adefovir dipivoxil results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO adefovir dipivoxil results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO adefovir dipivoxil results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO adefovir dipivoxil results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO adefovir dipivoxil results in increased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO adefovir dipivoxil results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Efna1 ephrin A1 decreases expression ISO adefovir dipivoxil results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO adefovir dipivoxil results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO adefovir dipivoxil results in increased expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO adefovir dipivoxil results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO adefovir dipivoxil results in increased expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 decreases expression ISO adefovir dipivoxil results in decreased expression of GALNT16 mRNA CTD PMID:25596134 NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO adefovir dipivoxil results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO adefovir dipivoxil results in increased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO adefovir dipivoxil results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO adefovir dipivoxil results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ifng interferon gamma multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il19 interleukin 19 increases secretion ISO adefovir dipivoxil results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO adefovir dipivoxil results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO adefovir dipivoxil results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Krt15 keratin 15 increases expression ISO adefovir dipivoxil results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO adefovir dipivoxil results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO adefovir dipivoxil results in increased secretion of LCN2 protein CTD PMID:24714768 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO adefovir dipivoxil results in increased expression of MAP3K8 mRNA CTD PMID:25596134 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO adefovir dipivoxil results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO adefovir dipivoxil results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO adefovir dipivoxil results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
JBrowse link
G Ninj1 ninjurin 1 increases expression ISO adefovir dipivoxil results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO adefovir dipivoxil results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO adefovir dipivoxil results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260
Ensembl chr19:53,695,976...53,715,202
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO adefovir dipivoxil results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO adefovir dipivoxil results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pgr progesterone receptor multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO adefovir dipivoxil results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pir pirin increases expression ISO adefovir dipivoxil results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Plec plectin increases expression ISO adefovir dipivoxil results in increased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO adefovir dipivoxil affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO adefovir dipivoxil results in increased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO adefovir dipivoxil results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO adefovir dipivoxil results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO adefovir dipivoxil results in decreased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO adefovir dipivoxil results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO adefovir dipivoxil results in increased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO adefovir dipivoxil results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Sesn1 sestrin 1 increases expression ISO adefovir dipivoxil results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sfn stratifin increases expression ISO adefovir dipivoxil results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO adefovir dipivoxil results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:26,249,978...26,342,170
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO adefovir dipivoxil results in increased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO adefovir dipivoxil results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO adefovir dipivoxil results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO adefovir dipivoxil results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Tp53 tumor protein p53 affects activity ISO adefovir dipivoxil affects the activity of TP53 protein CTD PMID:25596134 PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO adefovir dipivoxil results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression ISO adefovir dipivoxil results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO adefovir dipivoxil results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O decreases expression ISO adefovir dipivoxil results in decreased expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:101,765,572...101,812,736
Ensembl chr10:101,766,005...101,812,899
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO adefovir dipivoxil results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
amantadine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA CTD PMID:19211973 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO Amantadine results in increased expression of IFI27 mRNA CTD PMID:16756086 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 affects expression ISO Amantadine affects the expression of IFNAR1 mRNA CTD PMID:16756086 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Amantadine results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO Amantadine results in decreased expression of MAP2 mRNA CTD PMID:34748853 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Amantadine results in increased expression of OAS2 mRNA CTD PMID:16756086 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Amantadine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Amantadine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1 CTD PMID:15918519 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 decreases activity ISO Amantadine analog results in decreased activity of TDP1 protein CTD PMID:29248742 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021
JBrowse link
amprenavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO amprenavir results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
affects binding
ISO ABCB1 protein results in increased transport of amprenavir
[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir
amprenavir binds to ABCB1 protein
CTD PMID:23976943 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO amprenavir results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO amprenavir results in increased expression of CCL3 protein CTD PMID:17668557 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO amprenavir results in decreased activity of CYP3A4 protein CTD PMID:15523003 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir] CTD PMID:18799805 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
aphidicolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein]; [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA] CTD PMID:22003191 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Aphidicolin results in increased expression of CCNA2 mRNA CTD PMID:14738865 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein] CTD PMID:22003191 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]]
[7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]
CTD PMID:18158334 PMID:22003191 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Aphidicolin results in increased expression of CYP26A1 mRNA CTD PMID:29990529 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Aphidicolin results in increased expression of FGF8 mRNA CTD PMID:29990529 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Aphidicolin inhibits the reaction [Docetaxel results in increased expression of H2AX protein] CTD PMID:20878124 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Aphidicolin results in decreased expression of HOXB9 mRNA CTD PMID:29990529 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Hoxc6 homeo box C6 decreases expression ISO Aphidicolin results in decreased expression of HOXC6 mRNA CTD PMID:29990529 NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases activity ISO
EXP
Aphidicolin results in decreased activity of POLA1 protein CTD PMID:224865 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] CTD PMID:18158334 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO Aphidicolin results in increased expression of RXRA mRNA CTD PMID:14738865 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Aphidicolin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tbx6 T-box transcription factor 6 decreases expression ISO Aphidicolin results in decreased expression of TBX6 mRNA CTD PMID:29990529 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 increases expression ISO Aphidicolin results in increased expression of TNFRSF8 protein CTD PMID:12441127 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trim28 tripartite motif-containing 28 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein] CTD PMID:22003191 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Wnt3a Wnt family member 3A decreases expression ISO Aphidicolin results in decreased expression of WNT3A mRNA CTD PMID:29990529 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Aphidicolin CTD PMID:21785230 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
atazanavir sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Atazanavir Sulfate results in decreased activity of ABCB11 protein
Atazanavir Sulfate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of Atazanavir Sulfate
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ABCB1 mRNA
CTD PMID:29859254 PMID:33819548 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ABCB4 mRNA CTD PMID:33819548 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Atazanavir Sulfate results in decreased expression of ABCC2 mRNA CTD PMID:32152650 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO Atazanavir Sulfate results in decreased expression of ABCC3 mRNA CTD PMID:32152650 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of ABCG2 mRNA CTD PMID:33819548 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ABCG5 mRNA CTD PMID:33819548 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ABCG8 mRNA CTD PMID:33819548 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ACSL1 mRNA CTD PMID:33819548 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of ADGRG1 mRNA CTD PMID:33819548 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ADH1C mRNA CTD PMID:33819548 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ADH4 mRNA CTD PMID:33819548 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ADH6 mRNA CTD PMID:33819548 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of AKR1D1 mRNA CTD PMID:33819548 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of AKR7A3 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A3 mRNA
CTD PMID:32152650 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Alb albumin affects binding
multiple interactions
ISO Atazanavir Sulfate binds to ALB protein
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ALB mRNA
CTD PMID:15814459 PMID:16336266 PMID:33819548 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ALPP mRNA CTD PMID:33819548 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of AMPD3 mRNA CTD PMID:33819548 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of APOA1 mRNA CTD PMID:33819548 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF4 mRNA
Atazanavir Sulfate results in increased expression of ATF4 mRNA
CTD PMID:32152650 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF6 mRNA
Atazanavir Sulfate results in increased expression of ATF6 mRNA
CTD PMID:32152650 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg7 autophagy related 7 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of ATG7 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATG7 mRNA
CTD PMID:32152650 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of ATP8B1 mRNA CTD PMID:33819548 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of BAAT mRNA CTD PMID:33819548 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of BCL2L1 mRNA CTD PMID:33819548 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Cat catalase decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CAT mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CAT mRNA
CTD PMID:32152650 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Atazanavir Sulfate results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Atazanavir Sulfate results in increased expression of CCL3 protein CTD PMID:17668557 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CHI3L1 mRNA CTD PMID:33819548 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CSF1 mRNA
Atazanavir Sulfate results in increased expression of CSF1 mRNA
CTD PMID:32152650 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CTNNB1 mRNA CTD PMID:33819548 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cttn cortactin multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of CTTN mRNA CTD PMID:33819548 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of CYLD mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CYLD mRNA
CTD PMID:32152650 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP1A2 mRNA CTD PMID:33819548 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP27A1 mRNA CTD PMID:33819548 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CYP2B6 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP2B6 mRNA
CTD PMID:32152650 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C9 mRNA CTD PMID:33819548 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CYP3A4 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP3A4 mRNA
CTD PMID:32152650 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP3A5 mRNA CTD PMID:33819548 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CYP7A1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA
CTD PMID:32152650 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP7B1 mRNA CTD PMID:33819548 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP8B1 mRNA CTD PMID:33819548 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DDIT3 mRNA
Atazanavir Sulfate results in increased expression of DDIT3 mRNA
CTD PMID:32152650 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of DNAJB9 mRNA CTD PMID:33819548 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC10 mRNA
Atazanavir Sulfate results in increased expression of DNAJC10 mRNA
CTD PMID:32152650 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of DNAJC12 mRNA CTD PMID:33819548 NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521
JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 increases expression ISO Atazanavir Sulfate results in increased expression of DNAJC9 mRNA CTD PMID:32152650 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA
Atazanavir Sulfate results in decreased expression of EPHX1 mRNA
CTD PMID:32152650 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FKBP5 mRNA
Atazanavir Sulfate results in decreased expression of FKBP5 mRNA
CTD PMID:32152650 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Atazanavir Sulfate results in decreased expression of FMO1 mRNA CTD PMID:32152650 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of FOSL1 mRNA
Atazanavir Sulfate results in increased expression of FOSL1 mRNA
CTD PMID:32152650 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of GGT1 mRNA CTD PMID:33819548 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of GJB1 mRNA CTD PMID:33819548 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gk glycerol kinase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of GK mRNA CTD PMID:33819548 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of GPRC5B mRNA CTD PMID:33819548 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GPX2 mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of GPX2 mRNA
Atazanavir Sulfate results in decreased expression of GPX2 mRNA
CTD PMID:32152650 PMID:33819548 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of GSTA1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTA1 mRNA
CTD PMID:32152650 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm4 glutathione S-transferase mu 4 multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM4 mRNA CTD PMID:32152650 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of HACL1 mRNA CTD PMID:33819548 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of HGF mRNA CTD PMID:33819548 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Atazanavir Sulfate promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin]; Ritonavir promotes the reaction [Atazanavir Sulfate results in increased expression of HMOX1 mRNA]
Atazanavir Sulfate results in increased expression of HMOX1 mRNA; Atazanavir Sulfate results in increased expression of HMOX1 protein
CTD PMID:26968795 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hpx hemopexin multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of HPX mRNA CTD PMID:33819548 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of HSPA5 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of HSPA5 mRNA
CTD PMID:32152650 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Atazanavir Sulfate results in increased expression of ICAM1 protein CTD PMID:26968795 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of IER3 mRNA CTD PMID:33819548 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of IFI27 mRNA CTD PMID:33819548 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of IGFBP1 mRNA CTD PMID:33819548 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of IL6 mRNA CTD PMID:33819548 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUN mRNA CTD PMID:32152650 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUND mRNA CTD PMID:32152650 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kynu kynureninase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of KYNU mRNA CTD PMID:33819548 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of LBP mRNA CTD PMID:33819548 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of LDLR mRNA CTD PMID:33819548 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lipc lipase C, hepatic type multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of LIPC mRNA CTD PMID:33819548 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of LY96 mRNA CTD PMID:33819548 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Maff MAF bZIP transcription factor F increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of MAFF mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFF mRNA
CTD PMID:32152650 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP1LC3B mRNA
Atazanavir Sulfate results in increased expression of MAP1LC3B mRNA
CTD PMID:32152650 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAP2K6 mRNA
Atazanavir Sulfate results in decreased expression of MAP2K6 mRNA
CTD PMID:32152650 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of MAPKAPK3 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAPKAPK3 mRNA
CTD PMID:32152650 NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MLKL mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of MLKL mRNA
Atazanavir Sulfate results in increased expression of MLKL mRNA
CTD PMID:32152650 PMID:33819548 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmut methylmalonyl-CoA mutase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of MMUT mRNA CTD PMID:33819548 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of MTTP mRNA CTD PMID:33819548 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding-like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of NFXL1 mRNA CTD PMID:33819548 NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,626,066...35,667,498
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of NR1H3 mRNA CTD PMID:33819548 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of NR1H4 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1H4 mRNA
CTD PMID:32152650 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of NR1I2 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I2 mRNA
CTD PMID:32152650 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I3 mRNA
Atazanavir Sulfate results in decreased expression of NR1I3 mRNA
CTD PMID:32152650 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pah phenylalanine hydroxylase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of PAH mRNA CTD PMID:33819548 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of PIK3C2G mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2G mRNA
CTD PMID:32152650 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of PIK3R1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3R1 mRNA
CTD PMID:32152650 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pon1 paraoxonase 1 decreases activity EXP Atazanavir Sulfate results in decreased activity of PON1 protein CTD PMID:27378623 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of PPARA mRNA CTD PMID:33819548 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of PPP1R3C mRNA CTD PMID:33819548 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Rala RAS like proto-oncogene A multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RALA mRNA CTD PMID:32152650 NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063
JBrowse link
G Reep5 receptor accessory protein 5 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of REEP5 mRNA CTD PMID:33819548 NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RIPK1 mRNA CTD PMID:32152650 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Scp2 sterol carrier protein 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SCP2 mRNA CTD PMID:33819548 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Sdc2 syndecan 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SDC2 mRNA CTD PMID:33819548 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Serpine1 serpin family E member 1 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of SERPINE1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA
CTD PMID:32152650 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of SH3GLB1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA
CTD PMID:32152650 NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SLC10A1 mRNA
Atazanavir Sulfate results in decreased expression of SLC10A1 mRNA
CTD PMID:32152650 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc17a1 solute carrier family 17 member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SLC17A1 mRNA CTD PMID:33819548 NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SLC22A1 mRNA CTD PMID:33819548 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc51a solute carrier family 51 member A multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51A mRNA CTD PMID:32152650 NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51B mRNA CTD PMID:32152650 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SOD2 mRNA
Atazanavir Sulfate results in increased expression of SOD2 mRNA
CTD PMID:32152650 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SORL1 mRNA CTD PMID:33819548 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA
Atazanavir Sulfate results in increased expression of SQSTM1 mRNA
CTD PMID:32152650 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of SREBF1 mRNA CTD PMID:33819548 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srp72 signal recognition particle 72 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of SRP72 mRNA CTD PMID:33819548 NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of SULT2A1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SULT2A1 mRNA
CTD PMID:32152650 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Tfpi tissue factor pathway inhibitor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of TFPI mRNA CTD PMID:33819548 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of TLR4 mRNA CTD PMID:33819548 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of TNFRSF10A mRNA CTD PMID:33819548 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of TNFSF10 mRNA CTD PMID:33819548 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in increased expression of TNFSF11 mRNA CTD PMID:33819548 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
cidofovir anhydrous term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Cidofovir results in increased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Cidofovir results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Cidofovir results in decreased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Cidofovir results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Cidofovir results in decreased expression of ACSL1 mRNA CTD PMID:25596134 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Agrn agrin increases expression ISO Cidofovir results in increased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO Cidofovir affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Cidofovir results in increased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO Cidofovir results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects expression ISO Cidofovir affects the expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects expression ISO Cidofovir affects the expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Cidofovir results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Cidofovir results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Cidofovir affects the expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434
Ensembl chr 8:110,864,975...110,884,419
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Cidofovir results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankra2 ankyrin repeat family A member 2 decreases expression ISO Cidofovir results in decreased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression ISO Cidofovir results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Cidofovir results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Cidofovir results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Cidofovir results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO Cidofovir affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atosa atos homolog A decreases expression ISO Cidofovir results in decreased expression of ATOSA mRNA CTD PMID:25596134 NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Cidofovir results in decreased expression of ATXN1 mRNA CTD PMID:25596134 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G Aurkb aurora kinase B increases expression ISO Cidofovir results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cidofovir results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Cidofovir results in increased expression of BAX; Cidofovir results in increased expression of BAX mRNA CTD PMID:12700662 PMID:25596134 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Cidofovir results in increased expression of BBC3 mRNA CTD PMID:25596134 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases expression ISO Cidofovir results in increased expression of BCAT2 mRNA CTD PMID:25596134 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Cidofovir results in decreased expression of BCL2 CTD PMID:12700662 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bend5 BEN domain containing 5 affects expression ISO Cidofovir affects the expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Cidofovir results in increased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Brd2 bromodomain containing 2 decreases expression ISO Cidofovir results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cidofovir results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C2h4orf3 similar to human chromosome 4 open reading frame 3 decreases expression ISO Cidofovir results in decreased expression of C4ORF3 mRNA CTD PMID:25596134 NCBI chr 2:211,055,925...211,057,685
Ensembl chr 2:211,055,911...211,057,681
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Cidofovir results in increased expression of CAMKK2 mRNA CTD PMID:25596134 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of CARS1 mRNA CTD PMID:25596134 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Casp3 caspase 3 decreases activity ISO Cidofovir results in decreased activity of CASP3 protein CTD PMID:11697818 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO Cidofovir results in decreased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Cidofovir results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Cidofovir results in decreased expression of CCNG2 mRNA CTD PMID:25596134 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Cidofovir results in increased expression of CDKN1A mRNA; Cidofovir results in increased expression of CDKN1A protein CTD PMID:11697818 PMID:25596134 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO Cidofovir results in increased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 decreases expression ISO Cidofovir results in decreased expression of CLIP4 mRNA CTD PMID:25596134 NCBI chr 6:23,616,280...23,697,625
Ensembl chr 6:23,616,281...23,677,874
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO Cidofovir results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 increases phosphorylation ISO CMPK1 protein results in increased phosphorylation of Cidofovir CTD PMID:21128666 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Coch cochlin increases expression ISO Cidofovir results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109
JBrowse link
G Col4a1 collagen type IV alpha 1 chain affects expression ISO Cidofovir affects the expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cp ceruloplasmin increases expression ISO Cidofovir results in increased expression of CP mRNA CTD PMID:25596134 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO Cidofovir results in decreased expression of CTDP1 mRNA CTD PMID:25596134 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457
JBrowse link
G Ctsc cathepsin C increases expression ISO Cidofovir results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Cttn cortactin increases expression ISO Cidofovir results in increased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Cidofovir results in decreased expression of CYP1A1 mRNA CTD PMID:25596134 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Cidofovir results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO Cidofovir results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO Cidofovir results in decreased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO Cidofovir affects the expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Cidofovir results in decreased expression of DDX17 mRNA CTD PMID:25596134 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Cidofovir results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Dhx37 DEAH-box helicase 37 decreases expression ISO Cidofovir results in decreased expression of DHX37 mRNA CTD PMID:25596134 NCBI chr12:31,194,782...31,214,890
Ensembl chr12:31,194,859...31,216,802
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Cidofovir results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Cidofovir results in increased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression ISO Cidofovir results in increased expression of DPM3 mRNA CTD PMID:25596134 NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO Cidofovir results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression ISO Cidofovir results in increased expression of DUSP22 mRNA CTD PMID:25596134 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Cidofovir results in increased expression of DUSP5 mRNA CTD PMID:25596134 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Efna1 ephrin A1 decreases expression ISO Cidofovir results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Cidofovir results in decreased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO Cidofovir results in decreased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
JBrowse link
G Eno2 enolase 2 increases expression ISO Cidofovir results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Enosf1 enolase superfamily member 1 decreases expression ISO Cidofovir results in decreased expression of ENOSF1 mRNA CTD PMID:25596134 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 increases expression ISO Cidofovir results in increased expression of ENTPD7 mRNA CTD PMID:25596134 NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447
JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO Cidofovir results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of EPRS1 mRNA CTD PMID:25596134 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Cidofovir results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Cidofovir results in decreased expression of FAM162A mRNA CTD PMID:25596134 NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression ISO Cidofovir results in increased expression of FAM210A mRNA CTD PMID:25596134 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression ISO Cidofovir results in increased expression of FAM210B mRNA CTD PMID:25596134 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Cidofovir results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631
JBrowse link
G Fas Fas cell surface death receptor affects expression ISO Cidofovir affects the expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO Cidofovir results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Cidofovir results in decreased expression of FBXO30 mRNA CTD PMID:25596134 NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
JBrowse link
G Fech ferrochelatase decreases expression ISO Cidofovir results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 affects expression ISO Cidofovir affects the expression of FLVCR2 mRNA CTD PMID:25596134 NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Cidofovir results in increased expression of FOSL1 mRNA CTD PMID:25596134 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit decreases expression ISO Cidofovir results in decreased expression of FOSL2 mRNA CTD PMID:25596134 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression ISO Cidofovir results in decreased expression of FREM2 mRNA CTD PMID:25596134 NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO Cidofovir results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO Cidofovir affects the expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases expression ISO Cidofovir results in increased expression of GBE1 mRNA CTD PMID:25596134 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Cidofovir results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Cidofovir results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Cidofovir results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Cidofovir results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Golim4 golgi integral membrane protein 4 decreases expression ISO Cidofovir results in decreased expression of GOLIM4 mRNA CTD PMID:25596134 NCBI chr 2:160,640,837...160,733,475
Ensembl chr 2:160,640,938...160,733,253
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO Cidofovir results in increased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpa33 glycoprotein A33 increases expression ISO Cidofovir results in increased expression of GPA33 mRNA CTD PMID:25596134 NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Cidofovir results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO Cidofovir results in decreased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr87 G protein-coupled receptor 87 decreases expression ISO Cidofovir results in decreased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:143,439,741...143,440,901
Ensembl chr 2:143,439,735...143,458,190
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Cidofovir results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Cidofovir results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions
increases secretion
ISO Probenecid inhibits the reaction [Cidofovir results in increased secretion of HAVCR1 protein]; Tenofovir inhibits the reaction [Cidofovir results in increased secretion of HAVCR1 protein] CTD PMID:29738843 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 decreases expression ISO Cidofovir results in decreased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:87,952,202...88,042,492
Ensembl chr 4:87,952,274...88,042,488
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity ISO Cidofovir affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Cidofovir results in increased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Cidofovir results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Cidofovir results in decreased expression of HSPA5 mRNA CTD PMID:25596134 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects expression ISO Cidofovir affects the expression of HTATIP2 mRNA CTD PMID:25596134 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Cidofovir results in decreased expression of IDS mRNA CTD PMID:25596134 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Igf2r insulin-like growth factor 2 receptor affects expression ISO Cidofovir affects the expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Il19 interleukin 19 increases secretion ISO Cidofovir results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Cidofovir results in increased expression of INKA2 mRNA CTD PMID:25596134 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Cidofovir results in increased expression of INSIG1 mRNA CTD PMID:25596134 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme increases expression ISO Cidofovir results in increased expression of ISCU mRNA CTD PMID:25596134 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 affects expression ISO Cidofovir affects the expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO Cidofovir affects the expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO Cidofovir results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO Cidofovir results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Cidofovir results in increased expression of KEAP1 mRNA CTD PMID:25596134 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Krt15 keratin 15 increases expression ISO Cidofovir results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt19 keratin 19 increases expression ISO Cidofovir results in increased expression of KRT19 mRNA CTD PMID:25596134 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Lama3 laminin subunit alpha 3 affects expression ISO Cidofovir affects the expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of LARS1 mRNA CTD PMID:25596134 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression ISO Cidofovir results in increased expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Lratd2 LRAT domain containing 2 increases expression ISO Cidofovir results in increased expression of LRATD2 mRNA CTD PMID:25596134 NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Cidofovir results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Cidofovir results in decreased expression of MAN1A2 mRNA CTD PMID:25596134 NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO Cidofovir results in increased expression of MAPRE2 mRNA CTD PMID:25596134 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044
JBrowse link
G Mdm2 MDM2 proto-oncogene affects expression ISO Cidofovir affects the expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Cidofovir results in increased expression of MT2A mRNA CTD PMID:25596134 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtdh metadherin decreases expression ISO Cidofovir results in decreased expression of MTDH mRNA CTD PMID:25596134 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mtfp1 mitochondrial fission process 1 increases expression ISO Cidofovir results in increased expression of MTFP1 mRNA CTD PMID:25596134 NCBI chr14:78,968,434...78,972,274
Ensembl chr14:78,968,442...78,972,274
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Cidofovir results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Cidofovir results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of NARS1 mRNA CTD PMID:25596134 NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 affects expression ISO Cidofovir affects the expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,968,814...157,992,314
Ensembl chr 4:157,968,815...157,992,020
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Cidofovir results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects activity
affects expression
ISO Cidofovir affects the activity of NFE2L2 protein
Cidofovir affects the expression of NFE2L2 mRNA
CTD PMID:25596134 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nin ninein decreases expression ISO Cidofovir results in decreased expression of NIN mRNA CTD PMID:25596134 NCBI chr 6:88,525,405...88,627,710
Ensembl chr 6:88,525,742...88,627,639
JBrowse link
G Ninj1 ninjurin 1 increases expression ISO Cidofovir results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Cidofovir results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Cidofovir results in decreased expression of NR3C1 mRNA CTD PMID:25596134 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrep neuronal regeneration related protein increases expression ISO Cidofovir results in increased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO Cidofovir results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260
Ensembl chr19:53,695,976...53,715,202
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression ISO Cidofovir affects the expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial increases expression ISO Cidofovir results in increased expression of OXSM mRNA CTD PMID:25596134 NCBI chr15:9,210,443...9,215,852
Ensembl chr15:9,210,547...9,214,558
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Cidofovir results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO Cidofovir results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Cidofovir results in decreased expression of PDE8A mRNA CTD PMID:25596134 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Cidofovir results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Cidofovir results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO Cidofovir results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 affects expression ISO Cidofovir affects the expression of PFKFB4 mRNA CTD PMID:25596134 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects expression ISO Cidofovir affects the expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Cidofovir results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pidd1 p53-induced death domain protein 1 affects expression ISO Cidofovir affects the expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pir pirin increases expression ISO Cidofovir results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Plec plectin decreases expression ISO Cidofovir results in decreased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Cidofovir results in increased expression of PLK3 mRNA CTD PMID:25596134 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 affects expression ISO Cidofovir affects the expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression ISO Cidofovir results in increased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 increases expression ISO Cidofovir results in increased expression of PNPLA6 mRNA CTD PMID:25596134 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Podxl podocalyxin-like decreases expression ISO Cidofovir results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Polr3f RNA polymerase III subunit F decreases expression ISO Cidofovir results in decreased expression of POLR3F mRNA CTD PMID:25596134 NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO Cidofovir affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppfibp1 PPFIA binding protein 1 increases expression ISO Cidofovir results in increased expression of PPFIBP1 mRNA CTD PMID:25596134 NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
JBrowse link
G Ppig peptidylprolyl isomerase G decreases expression ISO Cidofovir results in decreased expression of PPIG mRNA CTD PMID:25596134 NCBI chr 3:54,484,023...54,512,929
Ensembl chr 3:54,484,023...54,512,926
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Cidofovir results in increased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 decreases expression ISO Cidofovir results in decreased expression of PPP4R2 mRNA CTD PMID:25596134 NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Cidofovir results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO Cidofovir results in decreased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO Cidofovir results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 increases expression ISO Cidofovir results in increased expression of PRPS1 mRNA CTD PMID:25596134 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Cidofovir results in increased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Cidofovir results in decreased expression of PSPC1 mRNA CTD PMID:25596134 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Cidofovir results in increased expression of PYCR1 mRNA CTD PMID:25596134 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression ISO Cidofovir results in increased expression of RAB26 mRNA CTD PMID:25596134 NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO Cidofovir results in increased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Cidofovir results in increased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Cidofovir results in increased expression of RFFL mRNA CTD PMID:25596134 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO Cidofovir results in increased expression of RIT1 mRNA CTD PMID:25596134 NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
JBrowse link
G Rlf RLF zinc finger decreases expression ISO Cidofovir results in decreased expression of RLF mRNA CTD PMID:25596134 NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257
JBrowse link
G Rnd1 Rho family GTPase 1 increases expression ISO Cidofovir results in increased expression of RND1 mRNA CTD PMID:25596134 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
JBrowse link
G Rnd3 Rho family GTPase 3 affects expression ISO Cidofovir affects the expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO Cidofovir results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:156,377,368...156,439,936
Ensembl chr 1:156,377,364...156,446,826
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Cidofovir results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Cidofovir results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression ISO Cidofovir results in decreased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 affects expression ISO Cidofovir affects the expression of RSL1D1 mRNA CTD PMID:25596134 NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression ISO Cidofovir results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:32,839,840...32,859,820
Ensembl chr12:32,839,809...32,859,799
JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Cidofovir results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Cidofovir results in increased expression of RUNX2 mRNA CTD PMID:25596134 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 increases expression ISO Cidofovir results in increased expression of SDF2L1 mRNA CTD PMID:25596134 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Cidofovir results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Cidofovir results in increased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
JBrowse link
G Sesn1 sestrin 1 increases expression ISO Cidofovir results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Setx senataxin decreases expression ISO Cidofovir results in decreased expression of SETX mRNA CTD PMID:25596134 NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803
JBrowse link
G Sfn stratifin increases expression ISO Cidofovir results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO Cidofovir results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Cidofovir affects the expression of SHANK3 mRNA CTD PMID:25596134 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 affects expression ISO Cidofovir affects the expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Sik1 salt-inducible kinase 1 affects expression ISO Cidofovir affects the expression of SIK1 mRNA CTD PMID:25596134 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Cidofovir results in decreased expression of SIPA1L2 mRNA CTD PMID:25596134 NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Cidofovir results in increased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Slc12a8 solute carrier family 12, member 8 affects expression ISO Cidofovir affects the expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO Cidofovir results in increased expression of SLC1A4 mRNA CTD PMID:25596134 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Cidofovir results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases import
multiple interactions
increases response to substance
ISO SLC22A6 protein results in increased import of Cidofovir
SLC22A6 protein results in increased uptake of and results in increased susceptibility to Cidofovir
SLC22A6 protein results in increased susceptibility to Cidofovir
CTD PMID:23856525 PMID:25448811 PMID:29738843 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance ISO SLC22A8 protein results in increased susceptibility to Cidofovir CTD PMID:25448811 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO Cidofovir results in increased expression of SLC25A20 mRNA CTD PMID:25596134 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Cidofovir results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Cidofovir results in increased expression of SLC2A1 mRNA CTD PMID:25596134 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cidofovir results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression ISO Cidofovir affects the expression of SLC6A6 mRNA CTD PMID:25596134 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO Cidofovir results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression ISO Cidofovir results in increased expression of SLC7A1 mRNA CTD PMID:25596134 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Cidofovir results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO Cidofovir results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO Cidofovir results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:26,250,178...26,342,151
Ensembl chr 9:26,249,978...26,342,170
JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Cidofovir results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO Cidofovir results in decreased expression of SORL1 mRNA CTD PMID:25596134 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 affects expression ISO Cidofovir affects the expression of SPRY1 mRNA CTD PMID:25596134 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression ISO Cidofovir results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Cidofovir results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Strbp spermatid perinuclear RNA binding protein decreases expression ISO Cidofovir results in decreased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Cidofovir results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Taldo1 transaldolase 1 increases expression ISO Cidofovir results in increased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Taok1 TAO kinase 1 decreases expression ISO Cidofovir results in decreased expression of TAOK1 mRNA CTD PMID:25596134 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO Cidofovir results in increased expression of TBXAS1 mRNA CTD PMID:25596134 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Cidofovir results in decreased expression of TFAP2A mRNA CTD PMID:25596134 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Cidofovir results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b affects expression ISO Cidofovir affects the expression of TIMM17B mRNA CTD PMID:25596134 NCBI chr  X:14,596,330...14,603,491
Ensembl chr  X:14,594,577...14,603,416
JBrowse link
G Tinag tubulointerstitial nephritis antigen decreases expression ISO Cidofovir results in decreased expression of TINAG mRNA CTD PMID:25596134 NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Cidofovir results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO Cidofovir results in decreased expression of TMEM45B mRNA CTD PMID:25596134 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453
JBrowse link
G Tmem94 transmembrane protein 94 decreases expression ISO Cidofovir results in decreased expression of TMEM94 mRNA CTD PMID:25596134 NCBI chr10:100,991,523...101,027,046
Ensembl chr10:100,991,573...101,027,394
JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 decreases expression ISO Cidofovir results in decreased expression of TMTC2 mRNA CTD PMID:25596134 NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Cidofovir results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
JBrowse link
G Top1 DNA topoisomerase I affects expression ISO Cidofovir affects the expression of TOP1 mRNA CTD PMID:25596134 NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
ISO Cidofovir results in increased expression of TP53 protein
Cidofovir affects the activity of TP53 protein
CTD PMID:11697818 PMID:25596134 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Cidofovir results in increased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 affects expression ISO Cidofovir affects the expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpcn1 two pore segment channel 1 increases expression ISO Cidofovir results in increased expression of TPCN1 mRNA CTD PMID:25596134 NCBI chr12:35,972,813...36,029,632
Ensembl chr12:35,972,846...36,029,626
JBrowse link
G Tpd52l1 TPD52 like 1 affects expression ISO Cidofovir affects the expression of TPD52L1 mRNA CTD PMID:25596134 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression ISO Cidofovir results in increased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO Cidofovir results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Cidofovir results in decreased expression of TSPAN12 mRNA CTD PMID:25596134 NCBI chr 4:50,313,768...50,389,246
Ensembl chr 4:50,313,772...50,389,246
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Cidofovir results in increased expression of TXN mRNA CTD PMID:25596134 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Cidofovir results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 increases expression ISO Cidofovir results in increased expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:10,983,734...11,005,468
Ensembl chr20:10,983,742...11,005,447
JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O affects expression ISO Cidofovir affects the expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:101,765,572...101,812,736
Ensembl chr10:101,766,005...101,812,899
JBrowse link
G Unkl unk like zinc finger affects expression ISO Cidofovir affects the expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225
JBrowse link
G Usp3 ubiquitin specific peptidase 3 affects expression ISO Cidofovir affects the expression of USP3 mRNA CTD PMID:25596134 NCBI chr 8:67,078,249...67,154,109
Ensembl chr 8:67,079,927...67,154,111
JBrowse link
G Vegfb vascular endothelial growth factor B increases expression ISO Cidofovir results in increased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 increases expression ISO Cidofovir results in increased expression of VIPR1 mRNA CTD PMID:25596134 NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 increases expression ISO Cidofovir results in increased expression of VTCN1 mRNA CTD PMID:25596134 NCBI chr 2:188,253,594...188,321,658
Ensembl chr 2:188,253,594...188,321,658
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO Cidofovir results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr16:44,258,372...44,421,815
Ensembl chr16:44,258,372...44,421,812
JBrowse link
G Xbp1 X-box binding protein 1 affects activity
increases expression
ISO Cidofovir affects the activity of XBP1 protein
Cidofovir results in increased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO Cidofovir results in increased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 affects expression ISO Cidofovir affects the expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Yeats2 YEATS domain containing 2 affects expression ISO Cidofovir affects the expression of YEATS2 mRNA CTD PMID:25596134 NCBI chr11:80,743,134...80,829,253
Ensembl chr11:80,743,134...80,829,208
JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 decreases expression ISO Cidofovir results in decreased expression of YTHDC2 mRNA CTD PMID:25596134 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,265,836...37,331,023
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Cidofovir results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863
JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
JBrowse link
costunolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP costunolide results in increased activity of CAT protein CTD PMID:20709041 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Il10 interleukin 10 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Ins1 insulin 1 multiple interactions EXP costunolide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:19007766 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of NOS2 protein] CTD PMID:26970604 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of PCNA protein] CTD PMID:26970604 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of PTGS2 protein] CTD PMID:26970604 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:26970604 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
delavirdine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO Delavirdine results in decreased activity of CYP2C9 protein CTD PMID:11225565 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
didanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Didanosine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Il24 interleukin 24 decreases expression ISO Didanosine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression
multiple interactions
ISO Didanosine results in decreased expression of COX2 mRNA
tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA]
CTD PMID:16940060 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Didanosine CTD PMID:19164483 NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Didanosine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
efavirenz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO efavirenz inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
efavirenz results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
decreases secretion
ISO efavirenz results in decreased expression of ADIPOQ mRNA
efavirenz results in decreased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alb albumin affects binding ISO efavirenz binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Bcl2l11 Bcl2-like 11 increases response to substance
increases expression
ISO BCL2L11 protein results in increased susceptibility to efavirenz metabolite
efavirenz metabolite results in increased expression of BCL2L11 mRNA; efavirenz metabolite results in increased expression of BCL2L11 protein; efavirenz results in increased expression of BCL2L11 mRNA; efavirenz results in increased expression of BCL2L11 protein
CTD PMID:21958719 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Canx calnexin affects localization ISO efavirenz affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
efavirenz metabolite results in increased cleavage of and results in increased activity of CASP3 protein; efavirenz results in increased cleavage of and results in increased activity of CASP3 protein
[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein]
CTD PMID:21958719 PMID:36309141 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in decreased activity of CAT protein CTD PMID:34118364 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO efavirenz results in increased secretion of CCL2 protein CTD PMID:21619898 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO efavirenz results in decreased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
decreases activity
multiple interactions
increases metabolic processing
ISO CYP2B6 gene polymorphism affects the metabolism of efavirenz; CYP2B6 protein affects the metabolism of efavirenz
efavirenz results in decreased activity of CYP2B6 protein
[efavirenz results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion; [efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in increased metabolism of efavirenz
CTD PMID:15622315 PMID:15769884 PMID:17041008 PMID:17559344 PMID:26599973 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO efavirenz results in decreased activity of CYP2C9 protein CTD PMID:11225565 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO efavirenz results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
increases expression
increases activity
ISO efavirenz results in decreased activity of CYP3A4 protein
efavirenz results in increased expression of CYP3A4 mRNA
efavirenz results in increased activity of CYP3A4 protein
CTD PMID:15980690 PMID:16837568 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO efavirenz results in increased expression of DDIT3 protein CTD PMID:28940366 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnm1l dynamin 1-like affects localization ISO efavirenz affects the localization of DNM1L protein modified form CTD PMID:28940366 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO efavirenz results in increased expression of EIF2AK3 protein modified form CTD PMID:28940366 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO efavirenz results in increased expression of FIS1 mRNA CTD PMID:28940366 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Hgf hepatocyte growth factor increases secretion ISO efavirenz results in increased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein] CTD PMID:36309141 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases secretion ISO efavirenz results in increased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of JUN protein; efavirenz results in increased phosphorylation of JUN protein CTD PMID:21958719 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Lep leptin decreases expression ISO efavirenz results in decreased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial multiple interactions
increases expression
increases response to substance
ISO efavirenz results in increased expression of and affects the localization of LONP1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [efavirenz results in increased expression of LONP1 mRNA]
LONP1 protein results in increased susceptibility to efavirenz
CTD PMID:28940366 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO efavirenz results in decreased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of MAP3K5 protein; efavirenz results in increased phosphorylation of MAP3K5 protein CTD PMID:21958719 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]
efavirenz metabolite results in increased phosphorylation of MAPK8 protein; efavirenz results in increased phosphorylation of MAPK8 protein
CTD PMID:21958719 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO efavirenz results in increased expression of MFN2 mRNA CTD PMID:28940366 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of MPO protein CTD PMID:34118364 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity EXP efavirenz results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity
ISO
EXP
[efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 PMID:27732639 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression ISO efavirenz results in increased expression of OPA1 mRNA CTD PMID:28940366 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO efavirenz results in decreased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 increases expression ISO efavirenz results in increased expression of RMDN3 protein CTD PMID:28940366 NCBI chr 3:106,125,961...106,146,568
Ensembl chr 3:106,125,951...106,146,586
JBrowse link
G Serpine1 serpin family E member 1 increases secretion ISO efavirenz results in increased secretion of SERPINE1 protein CTD PMID:21619898 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tg thyroglobulin increases expression ISO efavirenz results in increased expression of TG mRNA; efavirenz results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein] CTD PMID:36309141 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpo thyroid peroxidase increases expression ISO efavirenz results in increased expression of TPO mRNA; efavirenz results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein; efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO efavirenz results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
emtricitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Emtricitabine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Dck deoxycytidine kinase multiple interactions
affects binding
ISO DCK protein results in increased phosphorylation of and results in increased activity of Emtricitabine
Emtricitabine binds to DCK protein
CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions
ISO Emtricitabine results in decreased expression of PRKN protein
[Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein
CTD PMID:31545371 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein CTD PMID:31545371 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
enfuvirtide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects activity ISO enfuvirtide affects the activity of CYP1A2 protein CTD PMID:15656696 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects activity ISO enfuvirtide affects the activity of CYP2C19 protein CTD PMID:15656696 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects activity ISO enfuvirtide affects the activity of CYP2E1 protein CTD PMID:15656696 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
favipiravir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polg DNA polymerase gamma, catalytic subunit affects binding ISO favipiravir binds to POLG1 protein CTD PMID:36152797 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
JBrowse link
floxuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
decreases response to substance
ISO APEX1 protein mutant form results in increased susceptibility to Floxuridine
APEX1 protein results in decreased susceptibility to Floxuridine
CTD PMID:19470598 PMID:22194930 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Atr ATR serine/threonine kinase decreases response to substance ISO ATR protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Floxuridine CTD PMID:25354864 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases activity
ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK2 protein
Floxuridine results in increased activity of CHEK2 protein
CTD PMID:21613406 PMID:22194930 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
decreases response to substance
ISO olaparib inhibits the reaction [MLH1 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617