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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antiviral drug
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Accession:CHEBI:36044 term browser browse the term
Definition:A substance used in the prophylaxis or therapy of virus diseases.
Synonyms:related_synonym: anti-viral drug;   anti-virus drug;   antiviral drugs


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2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]
CTD PMID:31029725 NCBI chr 8:78,629,899...78,668,547 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA; 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein
CTD PMID:31029725 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein] CTD PMID:31029725 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA] CTD PMID:31029725 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:31029725 NCBI chr11:83,957,813...84,023,629 JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:31029725 NCBI chr 1:181,366,646...181,372,863 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased phosphorylation of MAPK8 protein
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]
CTD PMID:31029725 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone affects the localization of NFE2L2 protein]
CTD PMID:31029725 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the expression of and affects the stability of NFKBIA protein] CTD PMID:31029725 NCBI chr 6:72,858,713...72,861,941 JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA
NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NOS2 mRNA]
CTD PMID:31029725 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; SB 203580 inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]
CTD PMID:31029725 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; NFE2L2 protein affects the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of TNF mRNA] CTD PMID:31029725 NCBI chr20:3,622,011...3,624,629 JBrowse link
5-iodo-2'-deoxyuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase affects response to substance ISO MBD4 protein affects the susceptibility to Idoxuridine CTD PMID:16885370 NCBI chr 4:148,893,049...148,904,833 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Idoxuridine results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions EXP Idoxuridine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine] CTD PMID:8713072 NCBI chr 1:135,079,375...135,122,791 JBrowse link
G Tyms thymidylate synthetase affects uptake ISO TYMS protein affects the uptake of Idoxuridine CTD PMID:15001691 NCBI chr 9:113,313,454...113,329,551 JBrowse link
abacavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
decreases export
ISO [Estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir; [isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of abacavir]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of abacavir]
CTD PMID:17437964 PMID:19056916 PMID:25844889 NCBI chr 4:87,676,241...87,802,757 JBrowse link
G Alb albumin affects binding
multiple interactions
ISO abacavir binds to ALB protein
abacavir inhibits the reaction [Heme binds to ALB protein]; Heme inhibits the reaction [abacavir binds to ALB protein]
CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO abacavir results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:71,877,850...71,957,107 JBrowse link
G Crp C-reactive protein increases expression ISO abacavir results in increased expression of CRP protein CTD PMID:19891054 NCBI chr13:85,131,635...85,175,179 JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO abacavir results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,863,501...5,101,483 JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO abacavir results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr 1:244,584,477...244,590,359 JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO abacavir results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:49,186,034...49,188,736 JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO abacavir results in increased expression of GFAP protein CTD PMID:19358275 NCBI chr10:87,852,891...87,861,631 JBrowse link
G Hoxb7 homeo box B7 increases expression ISO abacavir results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr10:81,252,616...81,256,034 JBrowse link
G Hoxb9 homeo box B9 increases expression ISO abacavir results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,237,312...81,240,818 JBrowse link
G Ifng interferon gamma multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IFNG protein CTD PMID:23541086 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Il13 interleukin 13 multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IL13 protein CTD PMID:23541086 NCBI chr10:37,790,130...37,792,687 JBrowse link
G Il4 interleukin 4 affects response to substance ISO IL4 protein affects the susceptibility to abacavir CTD PMID:15867870 NCBI chr10:37,771,203...37,776,750 JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO abacavir results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:86,818,450...86,837,563 JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO abacavir results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:133,756,601...133,759,207 JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO abacavir results in increased expression of MMP9 protein CTD PMID:19891054 NCBI chr 3:153,684,158...153,692,118 JBrowse link
G Mpo myeloperoxidase increases expression ISO abacavir results in increased expression of MPO protein CTD PMID:19891054 NCBI chr10:72,594,458...72,608,862 JBrowse link
G Neurog2 neurogenin 2 increases expression ISO abacavir results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:216,092,641...216,095,276 JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO abacavir results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,081,259...14,083,336 JBrowse link
G Pax3 paired box 3 decreases expression ISO abacavir results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:79,567,455...79,664,042 JBrowse link
G Pax6 paired box 6 increases expression ISO abacavir results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:92,128,772...92,157,022 JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO [Quinine results in decreased activity of SLC22A1] which results in decreased uptake of abacavir CTD PMID:25844889 NCBI chr 1:48,076,657...48,103,679 JBrowse link
G Syp synaptophysin increases expression ISO abacavir results in increased expression of SYP protein CTD PMID:19358275 NCBI chr  X:14,849,444...14,864,553 JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO abacavir results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766 JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO abacavir results in decreased activity of TERT protein CTD PMID:19358275 NCBI chr 1:29,637,213...29,659,509 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of TNF protein CTD PMID:23541086 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO abacavir results in increased expression of UCP1 mRNA CTD PMID:14518702 NCBI chr19:24,808,782...24,816,853 JBrowse link
G Uncx UNC homeobox decreases expression ISO abacavir results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:15,092,779...15,097,300 JBrowse link
acyclovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
multiple interactions
ISO ABCG2 protein affects the transport of Acyclovir
tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of Acyclovir]
CTD PMID:21859328 NCBI chr 4:87,676,241...87,802,757 JBrowse link
G Aqp2 aquaporin 2 decreases expression EXP Acyclovir results in decreased expression of AQP2 protein CTD PMID:14675048 NCBI chr 7:130,711,433...130,716,468 JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases activity ISO Acyclovir results in decreased activity of HAAO protein CTD PMID:17174341 NCBI chr 6:10,845,235...10,864,863 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 decreases activity ISO Acyclovir results in decreased activity of IDO1 protein CTD PMID:17174341 NCBI chr16:67,430,684...67,442,459 JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Acyclovir results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055 JBrowse link
G Il1b interleukin 1 beta increases expression ISO Acyclovir results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386 JBrowse link
G Il24 interleukin 24 increases expression ISO Acyclovir results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487 JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Acyclovir affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Acyclovir results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Acyclovir results in decreased expression of SLC12A1 mRNA; Acyclovir results in decreased expression of SLC12A1 protein CTD PMID:14675048 NCBI chr 3:112,406,140...112,482,913 JBrowse link
G Slc17a1 solute carrier family 17 member 1 decreases expression EXP Acyclovir results in decreased expression of SLC17A1 mRNA; Acyclovir results in decreased expression of SLC17A1 protein CTD PMID:14675048 NCBI chr17:41,219,461...41,255,199 JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Acyclovir results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:134,382,002...134,517,622 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Acyclovir results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457 JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity EXP Acyclovir results in decreased activity of TDO2 protein CTD PMID:18665439 NCBI chr 2:167,269,581...167,287,511 JBrowse link
adefovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
affects transport
EXP Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] CTD PMID:21240898 PMID:21341280 NCBI chr 4:25,150,998...25,209,489 JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects abundance
increases export
ISO ABCC4 protein affects the abundance of adefovir
ABCC4 protein results in increased export of adefovir
CTD PMID:18364470 NCBI chr15:95,541,186...95,774,898 JBrowse link
G B2m beta-2 microglobulin increases secretion EXP adefovir results in increased secretion of B2M protein CTD PMID:27742868 NCBI chr 3:109,095,740...109,101,764 JBrowse link
G Calb1 calbindin 1 increases secretion EXP adefovir results in increased secretion of CALB1 protein CTD PMID:27742868 NCBI chr 5:29,375,624...29,402,532 JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion EXP adefovir results in increased secretion of HAVCR1 protein CTD PMID:27742868 NCBI chr10:31,118,667...31,151,730 JBrowse link
G Lcn2 lipocalin 2 increases secretion EXP adefovir results in increased secretion of LCN2 protein CTD PMID:27742868 NCBI chr 3:15,680,688...15,684,033 JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression
increases expression
ISO adefovir affects the expression of MMUT mRNA mutant form; adefovir affects the expression of MMUT protein mutant form
adefovir results in increased expression of MMUT mRNA; adefovir results in increased expression of MMUT protein
CTD PMID:19199343 PMID:19427250 NCBI chr 9:19,928,720...19,956,985 JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
affects response to substance
multiple interactions
increases response to substance
EXP
ISO
SLC22A6 protein results in increased uptake of adefovir
SLC22A6 protein affects the susceptibility to adefovir
adefovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to adefovir]; quercetin 3'-sulfate inhibits the reaction [SLC22A6 protein affects the susceptibility to adefovir]; SLC22A6 protein results in increased uptake of and results in increased susceptibility to adefovir
CTD PMID:16857889 PMID:21244849 PMID:23856525 PMID:25448811 NCBI chr 1:205,522,579...205,531,179 JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance ISO SLC22A8 protein results in increased susceptibility to adefovir CTD PMID:25448811 NCBI chr 1:205,496,331...205,516,378 JBrowse link
G Spp1 secreted phosphoprotein 1 increases secretion EXP adefovir results in increased secretion of SPP1 protein CTD PMID:27742868 NCBI chr14:5,308,885...5,315,120 JBrowse link
adefovir pivoxil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects activity ISO adefovir dipivoxil affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO adefovir dipivoxil results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:116,039,222...116,099,064 JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO adefovir dipivoxil results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013 JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO adefovir dipivoxil results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,967 JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO adefovir dipivoxil results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:119,982,272...120,017,416 JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO adefovir dipivoxil results in increased expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434 JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO adefovir dipivoxil results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:14,550,288...14,557,797 JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO adefovir dipivoxil results in decreased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:35,784,995...35,803,474 JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO adefovir dipivoxil results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:89,634,123...89,676,738 JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO adefovir dipivoxil results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Aurkb aurora kinase B increases expression ISO adefovir dipivoxil results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831 JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO adefovir dipivoxil results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:81,265,656...81,296,278 JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO adefovir dipivoxil results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member increases expression ISO adefovir dipivoxil results in increased expression of BCAR3 mRNA CTD PMID:25596134 NCBI chr 2:210,525,260...210,638,674 JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO adefovir dipivoxil results in decreased expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:126,290,648...126,336,662 JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO adefovir dipivoxil results in decreased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:105,499,534...105,520,159 JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO adefovir dipivoxil results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:45,531,881...45,535,642 JBrowse link
G Ccne2 cyclin E2 increases expression ISO adefovir dipivoxil results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,285,078...24,298,258 JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO adefovir dipivoxil results in increased expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:30,637,650...30,829,688 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO adefovir dipivoxil results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO adefovir dipivoxil results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007 JBrowse link
G Coch cochlin increases expression ISO adefovir dipivoxil results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:69,031,139...69,045,124 JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO adefovir dipivoxil results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412 JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO adefovir dipivoxil results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:246,975,888...247,002,234 JBrowse link
G Ctsc cathepsin C decreases expression ISO adefovir dipivoxil results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO adefovir dipivoxil results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO adefovir dipivoxil results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:77,185,114...77,207,650 JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO adefovir dipivoxil results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324 JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO adefovir dipivoxil results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:20,633,964...20,664,569 JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO adefovir dipivoxil results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:56,356,190...56,360,780 JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO adefovir dipivoxil results in increased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:234,947,910...235,006,173 JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO adefovir dipivoxil results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:35,374,429...35,480,462 JBrowse link
G Efna1 ephrin A1 decreases expression ISO adefovir dipivoxil results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:174,681,676...174,690,306 JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO adefovir dipivoxil results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440 JBrowse link
G Fas Fas cell surface death receptor increases expression ISO adefovir dipivoxil results in increased expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO adefovir dipivoxil results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981 JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:162,980,309...162,989,452 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO adefovir dipivoxil results in increased expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:96,154,789...96,157,091 JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 decreases expression ISO adefovir dipivoxil results in decreased expression of GALNT16 mRNA CTD PMID:25596134 NCBI chr 6:100,168,943...100,250,718 JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO adefovir dipivoxil results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:70,689,173...70,696,476 JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,805,312...18,807,893 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535 JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO adefovir dipivoxil results in increased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:143,439,741...143,440,901 JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO adefovir dipivoxil results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:41,391,106...41,392,611 JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO adefovir dipivoxil results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,855,104...3,859,148 JBrowse link
G Ifng interferon gamma multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr 7:53,903,339...53,907,375 JBrowse link
G Il19 interleukin 19 increases secretion ISO adefovir dipivoxil results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637 JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO adefovir dipivoxil results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,638,885...2,811,977 JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO adefovir dipivoxil results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073 JBrowse link
G Krt15 keratin 15 increases expression ISO adefovir dipivoxil results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO adefovir dipivoxil results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,523,168...3,751,722 JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO adefovir dipivoxil results in increased secretion of LCN2 protein CTD PMID:24714768 NCBI chr 3:15,680,688...15,684,033 JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO adefovir dipivoxil results in increased expression of MAP3K8 mRNA CTD PMID:25596134 NCBI chr17:53,382,908...53,403,216 JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO adefovir dipivoxil results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205 JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO adefovir dipivoxil results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682 JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO adefovir dipivoxil results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,968,814...157,992,314 JBrowse link
G Ninj1 ninjurin 1 increases expression ISO adefovir dipivoxil results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO adefovir dipivoxil results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,017,069...25,046,564 JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO adefovir dipivoxil results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260 JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO adefovir dipivoxil results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098 JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445 JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO adefovir dipivoxil results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087 JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:239,042,372...239,091,074 JBrowse link
G Pgr progesterone receptor multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,073,216...6,131,552 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO adefovir dipivoxil results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:47,193,250...47,196,335 JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:196,536,815...196,542,808 JBrowse link
G Pir pirin increases expression ISO adefovir dipivoxil results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269 JBrowse link
G Plec plectin increases expression ISO adefovir dipivoxil results in increased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:107,887,764...107,949,100 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:59,986,187...59,990,174 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO adefovir dipivoxil affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO adefovir dipivoxil results in increased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:70,172,603...70,208,607 JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO adefovir dipivoxil results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:134,250,086...134,271,765 JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:47,959,858...47,981,488 JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO adefovir dipivoxil results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:185,257,218...185,272,846 JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:213,196,709...213,218,564 JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO adefovir dipivoxil results in decreased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:83,883,490...83,928,932 JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO adefovir dipivoxil results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:67,562,483...67,567,418 JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO adefovir dipivoxil results in increased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:69,077,024...69,108,742 JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO adefovir dipivoxil results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:22,985,557...23,005,756 JBrowse link
G Sesn1 sestrin 1 increases expression ISO adefovir dipivoxil results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698 JBrowse link
G Sfn stratifin increases expression ISO adefovir dipivoxil results in increased expression of SFN mRNA CTD PMID:25596134
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001 JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:113,804,728...113,842,208 JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:131,374,562...131,408,733 JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO adefovir dipivoxil results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294 JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:26,250,178...26,342,151 JBrowse link
G Sulf2 sulfatase 2 increases expression ISO adefovir dipivoxil results in increased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:154,822,079...154,904,566 JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO adefovir dipivoxil results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,927,138...159,946,094 JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO adefovir dipivoxil results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327 JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO adefovir dipivoxil results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:1,944,017...1,946,351 JBrowse link
G Tp53 tumor protein p53 affects activity ISO adefovir dipivoxil affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO adefovir dipivoxil results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,253,986...24,272,250 JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression ISO adefovir dipivoxil results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525 JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO adefovir dipivoxil results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:41,267,534...41,270,053 JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O decreases expression ISO adefovir dipivoxil results in decreased expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:101,765,572...101,812,736 JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:141,535,815...141,564,029 JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO adefovir dipivoxil results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:115,106,050...115,136,863 JBrowse link
amantadine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA CTD PMID:19211973 NCBI chr 3:96,165,042...96,215,621 JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO Amantadine results in increased expression of IFI27 mRNA CTD PMID:16756086 NCBI chr 6:122,590,461...122,596,996 JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 affects expression ISO Amantadine affects the expression of IFNAR1 mRNA CTD PMID:16756086 NCBI chr11:30,725,774...30,752,227 JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 NCBI chr 5:115,780,248...115,888,841 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Amantadine results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009 JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Amantadine results in increased expression of OAS2 mRNA CTD PMID:16756086 NCBI chr12:35,802,824...35,830,778 JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Amantadine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617 JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Amantadine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937 JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1 CTD PMID:15918519 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 decreases activity ISO Amantadine analog results in decreased activity of TDP1 protein CTD PMID:29248742 NCBI chr 6:119,163,192...119,231,029 JBrowse link
amprenavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO amprenavir results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797 JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
affects binding
ISO ABCB1 protein results in increased transport of amprenavir
[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir
amprenavir binds to ABCB1 protein
CTD PMID:23976943 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO amprenavir results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO amprenavir results in increased expression of CCL3 protein CTD PMID:17668557 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir] CTD PMID:18799805 NCBI chr11:62,460,213...62,496,665 JBrowse link
aphidicolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein]; [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:53,828,741...53,932,773 JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:96,426,704...96,524,152 JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA] CTD PMID:22003191 NCBI chr 1:205,731,814...205,743,430 JBrowse link
G Ccna2 cyclin A2 increases expression ISO Aphidicolin results in increased expression of CCNA2 mRNA CTD PMID:14738865 NCBI chr 2:119,427,239...119,433,645 JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein] CTD PMID:22003191 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]]
[7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]
CTD PMID:18158334 PMID:22003191 NCBI chr12:45,788,823...45,821,382 JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Aphidicolin results in increased expression of CYP26A1 mRNA CTD PMID:29990529 NCBI chr 1:235,471,368...235,475,204 JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Aphidicolin results in increased expression of FGF8 mRNA CTD PMID:29990529 NCBI chr 1:244,584,477...244,590,359 JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Aphidicolin inhibits the reaction [Docetaxel results in increased expression of H2AX protein] CTD PMID:20878124 NCBI chr 8:44,671,927...44,673,257 JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Aphidicolin results in decreased expression of HOXB9 mRNA CTD PMID:29990529 NCBI chr10:81,237,312...81,240,818 JBrowse link
G Hoxc6 homeo box C6 decreases expression ISO Aphidicolin results in decreased expression of HOXC6 mRNA CTD PMID:29990529 NCBI chr 7:134,138,017...134,148,899 JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases activity ISO
EXP
Aphidicolin results in decreased activity of POLA1 protein CTD PMID:224865 NCBI chr  X:58,034,617...58,348,612 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] CTD PMID:18158334 NCBI chr11:85,040,790...85,258,357 JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO Aphidicolin results in increased expression of RXRA mRNA CTD PMID:14738865 NCBI chr 3:10,989,832...11,076,366 JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Aphidicolin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:140,604,490...140,610,050 JBrowse link
G Tbx6 T-box transcription factor 6 decreases expression ISO Aphidicolin results in decreased expression of TBX6 mRNA CTD PMID:29990529 NCBI chr 1:181,387,851...181,392,762 JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 increases expression ISO Aphidicolin results in increased expression of TNFRSF8 protein CTD PMID:12441127 NCBI chr 5:157,123,183...157,168,421 JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Trim28 tripartite motif-containing 28 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein] CTD PMID:22003191 NCBI chr 1:73,652,441...73,659,388 JBrowse link
G Wnt3a Wnt family member 3A decreases expression ISO Aphidicolin results in decreased expression of WNT3A mRNA CTD PMID:29990529 NCBI chr10:44,034,174...44,078,463 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Aphidicolin CTD PMID:21785230 NCBI chr 2:20,948,464...21,197,705 JBrowse link
atazanavir sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Atazanavir Sulfate results in decreased activity of ABCB11 protein
Atazanavir Sulfate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797 JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport ISO ABCB1 protein results in increased transport of Atazanavir Sulfate CTD PMID:29859254 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Atazanavir Sulfate results in decreased expression of ABCC2 mRNA CTD PMID:32152650 NCBI chr 1:242,664,657...242,723,239 JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO Atazanavir Sulfate results in decreased expression of ABCC3 mRNA CTD PMID:32152650 NCBI chr10:79,296,681...79,342,749 JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of AKR7A3 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A3 mRNA
CTD PMID:32152650 NCBI chr 5:151,590,968...151,601,394 JBrowse link
G Alb albumin affects binding ISO Atazanavir Sulfate binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF4 mRNA
Atazanavir Sulfate results in increased expression of ATF4 mRNA
CTD PMID:32152650 NCBI chr 7:111,804,135...111,806,457 JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF6 mRNA
Atazanavir Sulfate results in increased expression of ATF6 mRNA
CTD PMID:32152650 NCBI chr13:82,927,579...83,106,381 JBrowse link
G Atg7 autophagy related 7 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of ATG7 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATG7 mRNA
CTD PMID:32152650 NCBI chr 4:147,718,663...147,925,656 JBrowse link
G Cat catalase decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CAT mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CAT mRNA
CTD PMID:32152650 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Atazanavir Sulfate results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Atazanavir Sulfate results in increased expression of CCL3 protein CTD PMID:17668557 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CSF1 mRNA
Atazanavir Sulfate results in increased expression of CSF1 mRNA
CTD PMID:32152650 NCBI chr 2:195,377,215...195,396,608 JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of CYLD mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CYLD mRNA
CTD PMID:32152650 NCBI chr19:18,310,632...18,373,696 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CYP2B6 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP2B6 mRNA
CTD PMID:32152650 NCBI chr 1:81,652,762...81,732,153 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of CYP7A1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA
CTD PMID:32152650 NCBI chr 5:19,376,979...19,386,676 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DDIT3 mRNA
Atazanavir Sulfate results in increased expression of DDIT3 mRNA
CTD PMID:32152650 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC10 mRNA
Atazanavir Sulfate results in increased expression of DNAJC10 mRNA
CTD PMID:32152650 NCBI chr 3:65,232,031...65,272,732 JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 increases expression ISO Atazanavir Sulfate results in increased expression of DNAJC9 mRNA CTD PMID:32152650 NCBI chr15:3,923,842...3,928,118 JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA
Atazanavir Sulfate results in decreased expression of EPHX1 mRNA
CTD PMID:32152650 NCBI chr13:92,714,315...92,744,124 JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FKBP5 mRNA
Atazanavir Sulfate results in decreased expression of FKBP5 mRNA
CTD PMID:32152650 NCBI chr20:6,457,207...6,575,404 JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression ISO Atazanavir Sulfate results in decreased expression of FMO1 mRNA CTD PMID:32152650 NCBI chr13:75,182,184...75,214,439 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of FOSL1 mRNA
Atazanavir Sulfate results in increased expression of FOSL1 mRNA
CTD PMID:32152650 NCBI chr 1:202,754,549...202,763,057 JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GPX2 mRNA
Atazanavir Sulfate results in decreased expression of GPX2 mRNA
CTD PMID:32152650 NCBI chr 6:95,493,589...95,496,877 JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of GSTA1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTA1 mRNA
CTD PMID:32152650 NCBI chr 9:23,703,476...23,720,121 JBrowse link
G Gstm4 glutathione S-transferase mu 4 multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM4 mRNA CTD PMID:32152650 NCBI chr 2:195,667,940...195,685,315 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Atazanavir Sulfate promotes the reaction [HMOX1 protein results in increased chemical synthesis of Bilirubin]; Ritonavir promotes the reaction [Atazanavir Sulfate results in increased expression of HMOX1 mRNA]
Atazanavir Sulfate results in increased expression of HMOX1 mRNA; Atazanavir Sulfate results in increased expression of HMOX1 protein
CTD PMID:26968795 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of HSPA5 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of HSPA5 mRNA
CTD PMID:32152650 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Atazanavir Sulfate results in increased expression of ICAM1 protein CTD PMID:26968795 NCBI chr 8:19,553,063...19,565,438 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUN mRNA CTD PMID:32152650 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUND mRNA CTD PMID:32152650 NCBI chr16:18,734,121...18,735,799 JBrowse link
G Maff MAF bZIP transcription factor F increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of MAFF mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFF mRNA
CTD PMID:32152650 NCBI chr 7:110,912,499...110,923,851 JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP1LC3B mRNA
Atazanavir Sulfate results in increased expression of MAP1LC3B mRNA
CTD PMID:32152650 NCBI chr19:49,665,795...49,673,655 JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAP2K6 mRNA
Atazanavir Sulfate results in decreased expression of MAP2K6 mRNA
CTD PMID:32152650 NCBI chr10:95,373,304...95,490,406 JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of MAPKAPK3 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAPKAPK3 mRNA
CTD PMID:32152650 NCBI chr 8:107,929,754...107,963,638 JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MLKL mRNA
Atazanavir Sulfate results in increased expression of MLKL mRNA
CTD PMID:32152650 NCBI chr19:39,278,123...39,304,555 JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of NR1H4 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1H4 mRNA
CTD PMID:32152650 NCBI chr 7:23,846,122...23,942,085 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of NR1I2 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I2 mRNA
CTD PMID:32152650 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I3 mRNA
Atazanavir Sulfate results in decreased expression of NR1I3 mRNA
CTD PMID:32152650 NCBI chr13:83,632,940...83,638,193 JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of PIK3C2G mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2G mRNA
CTD PMID:32152650 NCBI chr 4:172,483,752...172,851,623 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of PIK3R1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3R1 mRNA
CTD PMID:32152650 NCBI chr 2:32,878,942...32,963,611 JBrowse link
G Pon1 paraoxonase 1 decreases activity EXP Atazanavir Sulfate results in decreased activity of PON1 protein CTD PMID:27378623 NCBI chr 4:33,294,737...33,325,759 JBrowse link
G Rala RAS like proto-oncogene A multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RALA mRNA CTD PMID:32152650 NCBI chr17:47,092,139...47,145,192 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RIPK1 mRNA CTD PMID:32152650 NCBI chr17:30,839,639...30,871,824 JBrowse link
G Serpine1 serpin family E member 1 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of SERPINE1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA
CTD PMID:32152650 NCBI chr12:19,601,272...19,611,657 JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 increases expression
multiple interactions
ISO Atazanavir Sulfate results in increased expression of SH3GLB1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA
CTD PMID:32152650 NCBI chr 2:233,750,838...233,784,817 JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
decreases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SLC10A1 mRNA
Atazanavir Sulfate results in decreased expression of SLC10A1 mRNA
CTD PMID:32152650 NCBI chr 6:100,613,045...100,626,670 JBrowse link
G Slc51a solute carrier family 51 subunit alpha multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51A mRNA CTD PMID:32152650 NCBI chr11:68,299,086...68,313,485 JBrowse link
G Slc51b solute carrier family 51 subunit beta multiple interactions ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51B mRNA CTD PMID:32152650 NCBI chr 8:65,931,891...65,934,893 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SOD2 mRNA
Atazanavir Sulfate results in increased expression of SOD2 mRNA
CTD PMID:32152650 NCBI chr 1:47,638,318...47,645,163 JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA
Atazanavir Sulfate results in increased expression of SQSTM1 mRNA
CTD PMID:32152650 NCBI chr10:34,525,517...34,536,685 JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression
multiple interactions
ISO Atazanavir Sulfate results in decreased expression of SULT2A1 mRNA
[Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SULT2A1 mRNA
CTD PMID:32152650 NCBI chr 1:75,451,178...75,508,142 JBrowse link
cidofovir anhydrous term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of AARS1 mRNA CTD PMID:25596134 NCBI chr19:38,999,130...39,021,152 JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Cidofovir results in increased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:76,668,554...76,677,263 JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Cidofovir results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:32,499,225...32,531,932 JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Cidofovir results in decreased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,126,687...9,182,948 JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Cidofovir results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:27,697,384...27,716,013 JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Cidofovir results in decreased expression of ACSL1 mRNA CTD PMID:25596134 NCBI chr16:45,755,246...45,821,541 JBrowse link
G Agrn agrin increases expression ISO Cidofovir results in increased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:166,749,306...166,782,212 JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO Cidofovir affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568 JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Cidofovir results in increased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:226,737,472...226,764,647 JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO Cidofovir results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:116,039,222...116,099,064 JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects expression ISO Cidofovir affects the expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:65,759,778...65,808,013 JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects expression ISO Cidofovir affects the expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:239,375,657...239,407,967 JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Cidofovir results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:119,982,272...120,017,416 JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Cidofovir results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:181,402,275...181,407,476 JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Cidofovir affects the expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:110,863,753...110,884,434 JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Cidofovir results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:14,550,288...14,557,797 JBrowse link
G Ankra2 ankyrin repeat family A member 2 decreases expression ISO Cidofovir results in decreased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr 2:29,612,867...29,623,748 JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression ISO Cidofovir results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:74,647,147...74,738,784 JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Cidofovir results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:35,784,995...35,803,474 JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Cidofovir results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:89,634,123...89,676,738 JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Cidofovir results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO Cidofovir affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:111,804,135...111,806,457 JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Cidofovir results in decreased expression of ATXN1 mRNA CTD PMID:25596134 NCBI chr17:18,737,491...19,142,360 JBrowse link
G Aurkb aurora kinase B increases expression ISO Cidofovir results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:53,744,290...53,750,831 JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cidofovir results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:81,265,656...81,296,278 JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Cidofovir results in increased expression of BAX; Cidofovir results in increased expression of BAX mRNA CTD PMID:12700662 PMID:25596134 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Cidofovir results in increased expression of BBC3 mRNA CTD PMID:25596134 NCBI chr 1:77,013,281...77,022,509 JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases expression ISO Cidofovir results in increased expression of BCAT2 mRNA CTD PMID:25596134 NCBI chr 1:96,040,407...96,060,008 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Cidofovir results in decreased expression of BCL2 CTD PMID:12700662 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bend5 BEN domain containing 5 affects expression ISO Cidofovir affects the expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:126,290,648...126,336,662 JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Cidofovir results in increased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:105,499,534...105,520,159 JBrowse link
G Brd2 bromodomain containing 2 decreases expression ISO Cidofovir results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:4,727,078...4,735,389 JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cidofovir results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:45,531,881...45,535,642 JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Cidofovir results in increased expression of CAMKK2 mRNA CTD PMID:25596134 NCBI chr12:33,791,023...33,845,000 JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression ISO Cidofovir results in decreased expression of CARS1 mRNA CTD PMID:25596134 NCBI chr 1:198,753,689...198,796,016 JBrowse link
G Casp3 caspase 3 decreases activity ISO Cidofovir results in decreased activity of CASP3 protein CTD PMID:11697818 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO Cidofovir results in decreased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:146,632,756...146,646,314 JBrowse link
G Ccne2 cyclin E2 increases expression ISO Cidofovir results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,285,078...24,298,258 JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Cidofovir results in decreased expression of CCNG2 mRNA CTD PMID:25596134 NCBI chr14:14,804,321...14,812,819 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Cidofovir results in increased expression of CDKN1A mRNA; Cidofovir results in increased expression of CDKN1A protein CTD PMID:11697818 PMID:25596134 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO Cidofovir results in increased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:130,859,993...130,897,979 JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 decreases expression ISO Cidofovir results in decreased expression of CLIP4 mRNA CTD PMID:25596134 NCBI chr 6:23,616,280...23,697,625 JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO Cidofovir results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:82,569,257...82,591,007 JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 increases phosphorylation ISO CMPK1 protein results in increased phosphorylation of Cidofovir CTD PMID:21128666 NCBI chr 5:128,480,301...128,507,830 JBrowse link
G Coch cochlin increases expression ISO Cidofovir results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:69,031,139...69,045,124 JBrowse link
G Col4a1 collagen type IV alpha 1 chain affects expression ISO Cidofovir affects the expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412 JBrowse link
G Cp ceruloplasmin increases expression ISO Cidofovir results in increased expression of CP mRNA CTD PMID:25596134 NCBI chr 2:102,439,433...102,498,075 JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO Cidofovir results in decreased expression of CTDP1 mRNA CTD PMID:25596134 NCBI chr18:73,854,277...73,916,232 JBrowse link
G Ctsc cathepsin C increases expression ISO Cidofovir results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:142,028,386...142,059,841 JBrowse link
G Cttn cortactin increases expression ISO Cidofovir results in increased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:199,599,710...199,635,254 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Cidofovir results in decreased expression of CYP1A1 mRNA CTD PMID:25596134 NCBI chr 8:58,096,021...58,102,130 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Cidofovir results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:15,342,312...15,350,886 JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO Cidofovir results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:77,185,114...77,207,650 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO Cidofovir results in decreased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO Cidofovir affects the expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:27,891,989...27,894,088 JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Cidofovir results in decreased expression of DDX17 mRNA CTD PMID:25596134 NCBI chr 7:111,091,127...111,109,353 JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Cidofovir results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:1,148,734...1,175,324 JBrowse link
G Dhx37 DEAH-box helicase 37 decreases expression ISO Cidofovir results in decreased expression of DHX37 mRNA CTD PMID:25596134 NCBI chr12:31,194,782...31,214,890 JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Cidofovir results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:20,633,964...20,664,569 JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Cidofovir results in increased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:61,270,385...61,276,795 JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression ISO Cidofovir results in increased expression of DPM3 mRNA CTD PMID:25596134 NCBI chr 2:174,676,532...174,677,047 JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO Cidofovir results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:35,374,429...35,480,462 JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression ISO Cidofovir results in increased expression of DUSP22 mRNA CTD PMID:25596134 NCBI chr17:33,780,980...33,831,540 JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Cidofovir results in increased expression of DUSP5 mRNA CTD PMID:25596134 NCBI chr 1:252,538,408...252,555,320 JBrowse link
G Efna1 ephrin A1 decreases expression ISO Cidofovir results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:174,681,676...174,690,306 JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Cidofovir results in decreased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:181,134,604...181,152,489 JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO Cidofovir results in decreased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:43,451,130...43,475,035 JBrowse link
G Eno2 enolase 2 increases expression ISO Cidofovir results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,572,085...157,580,971 JBrowse link
G Enosf1 enolase superfamily member 1 decreases expression ISO Cidofovir results in decreased expression of ENOSF1 mRNA CTD PMID:25596134 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 increases expression ISO Cidofovir results in increased expression of ENTPD7 mRNA CTD PMID:25596134 NCBI chr 1:242,559,365...242,601,044 JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO Cidofovir results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:45,891,886...46,002,523 JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Cidofovir results in decreased expression of EPRS1 mRNA CTD PMID:25596134 NCBI chr13:96,901,548...96,971,966 JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Cidofovir results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440 JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Cidofovir results in decreased expression of FAM162A mRNA CTD PMID:25596134 NCBI chr11:64,680,937...64,711,239 JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression ISO Cidofovir results in increased expression of FAM210A mRNA CTD PMID:25596134 NCBI chr18:61,846,447...61,886,123 JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression ISO Cidofovir results in increased expression of FAM210B mRNA CTD PMID:25596134 NCBI chr 3:161,118,228...161,128,400 JBrowse link
G Fam214a family with sequence similarity 214, member A decreases expression ISO Cidofovir results in decreased expression of FAM214A mRNA CTD PMID:25596134 NCBI chr 8:75,694,828...75,772,565 JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Cidofovir results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:52,710,003...52,722,591 JBrowse link
G Fas Fas cell surface death receptor affects expression ISO Cidofovir affects the expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO Cidofovir results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981 JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Cidofovir results in decreased expression of FBXO30 mRNA CTD PMID:25596134 NCBI chr 1:5,655,341...5,671,558 JBrowse link
G Fech ferrochelatase decreases expression ISO Cidofovir results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:57,945,123...57,978,327 JBrowse link
G Flvcr2 FLVCR heme transporter 2 affects expression ISO Cidofovir affects the expression of FLVCR2 mRNA CTD PMID:25596134 NCBI chr 6:105,408,355...105,472,355 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Cidofovir results in increased expression of FOSL1 mRNA CTD PMID:25596134 NCBI chr 1:202,754,549...202,763,057 JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit decreases expression ISO Cidofovir results in decreased expression of FOSL2 mRNA CTD PMID:25596134 NCBI chr 6:24,297,898...24,319,157 JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression ISO Cidofovir results in decreased expression of FREM2 mRNA CTD PMID:25596134 NCBI chr 2:137,602,784...137,740,785 JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO Cidofovir results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:162,980,309...162,989,452 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO Cidofovir affects the expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:96,154,789...96,157,091 JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO Cidofovir results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:84,171,596...84,212,609 JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases expression ISO Cidofovir results in increased expression of GBE1 mRNA CTD PMID:25596134 NCBI chr11:8,734,806...9,000,226 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Cidofovir results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:78,629,899...78,668,547 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Cidofovir results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:210,347,482...210,367,537 JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Cidofovir results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:70,689,173...70,696,476 JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Cidofovir results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,805,312...18,807,893 JBrowse link
G Golim4 golgi integral membrane protein 4 decreases expression ISO Cidofovir results in decreased expression of GOLIM4 mRNA CTD PMID:25596134 NCBI chr 2:160,640,932...160,733,475 JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO Cidofovir results in increased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:242,357,293...242,381,535 JBrowse link
G Gpa33 glycoprotein A33 increases expression ISO Cidofovir results in increased expression of GPA33 mRNA CTD PMID:25596134 NCBI chr13:78,381,141...78,414,765 JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Cidofovir results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:8,715,367...8,768,051 JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO Cidofovir results in decreased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 4:78,010,247...78,031,491 JBrowse link
G Gpr87 G protein-coupled receptor 87 decreases expression ISO Cidofovir results in decreased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:143,439,741...143,440,901 JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Cidofovir results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:58,482,209...58,525,256 JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Cidofovir results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:41,391,106...41,392,611 JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions
increases secretion
ISO Probenecid inhibits the reaction [Cidofovir results in increased secretion of HAVCR1 protein]; Tenofovir inhibits the reaction [Cidofovir results in increased secretion of HAVCR1 protein] CTD PMID:29738843 NCBI chr10:31,118,667...31,151,730 JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 decreases expression ISO Cidofovir results in decreased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:87,952,202...88,042,492 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity ISO Cidofovir affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:92,624,059...92,669,262 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Cidofovir results in increased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:13,466,287...13,474,082 JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Cidofovir results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:3,855,104...3,859,148 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Cidofovir results in decreased expression of HSPA5 mRNA CTD PMID:25596134 NCBI chr 3:18,055,507...18,059,969 JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects expression ISO Cidofovir affects the expression of HTATIP2 mRNA CTD PMID:25596134 NCBI chr 1:99,473,411...99,488,632 JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:14,940,919...14,987,277 JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Cidofovir results in decreased expression of IDS mRNA CTD PMID:25596134 NCBI chr  X:149,025,977...149,046,639 JBrowse link
G Igf2r insulin-like growth factor 2 receptor affects expression ISO Cidofovir affects the expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 1:47,979,109...48,067,501 JBrowse link
G Il19 interleukin 19 increases secretion ISO Cidofovir results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:42,397,715...42,411,637 JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Cidofovir results in increased expression of INKA2 mRNA CTD PMID:25596134 NCBI chr 2:193,185,275...193,200,643 JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Cidofovir results in increased expression of INSIG1 mRNA CTD PMID:25596134 NCBI chr 4:7,315,494...7,323,972 JBrowse link
G Iscu iron-sulfur cluster assembly enzyme increases expression ISO Cidofovir results in increased expression of ISCU mRNA CTD PMID:25596134 NCBI chr12:42,852,305...42,858,150 JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 affects expression ISO Cidofovir affects the expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:161,684,249...161,698,315 JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO Cidofovir affects the expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr19:56,705,123...56,753,199 JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO Cidofovir results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,638,885...2,811,977 JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO Cidofovir results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:103,630,907...103,675,073 JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Cidofovir results in increased expression of KEAP1 mRNA CTD PMID:25596134 NCBI chr 8:19,768,375...19,777,862 JBrowse link
G Krt15 keratin 15 increases expression ISO Cidofovir results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:85,066,797...85,070,614 JBrowse link
G Krt19 keratin 19 increases expression ISO Cidofovir results in increased expression of KRT19 mRNA CTD PMID:25596134 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Lama3 laminin subunit alpha 3 affects expression ISO Cidofovir affects the expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,523,168...3,751,722 JBrowse link
G Lars1 leucyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of LARS1 mRNA CTD PMID:25596134 NCBI chr18:34,201,555...34,256,003 JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression ISO Cidofovir results in increased expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 4:145,393,153...145,452,049 JBrowse link
G LOC691807 hypothetical protein LOC691807 decreases expression ISO Cidofovir results in decreased expression of C4ORF3 mRNA CTD PMID:25596134 NCBI chr 2:211,055,925...211,057,685 JBrowse link
G Lratd2 LRAT domain containing 2 increases expression ISO Cidofovir results in increased expression of LRATD2 mRNA CTD PMID:25596134 NCBI chr 7:92,376,713...92,387,045 JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Cidofovir results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:26,603,903...26,660,871 JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Cidofovir results in decreased expression of MAN1A2 mRNA CTD PMID:25596134 NCBI chr 2:187,947,484...188,096,332 JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 increases expression ISO Cidofovir results in increased expression of MAPRE2 mRNA CTD PMID:25596134 NCBI chr18:15,028,675...15,169,553 JBrowse link
G Mdm2 MDM2 proto-oncogene affects expression ISO Cidofovir affects the expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205 JBrowse link
G Mt2A metallothionein 2A increases expression ISO Cidofovir results in increased expression of MT2A mRNA CTD PMID:25596134 NCBI chr19:10,832,009...10,832,783 JBrowse link
G Mtdh metadherin decreases expression ISO Cidofovir results in decreased expression of MTDH mRNA CTD PMID:25596134 NCBI chr 7:65,306,464...65,365,647 JBrowse link
G Mtfp1 mitochondrial fission process 1 increases expression ISO Cidofovir results in increased expression of MTFP1 mRNA CTD PMID:25596134 NCBI chr14:78,968,434...78,972,274 JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Cidofovir results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:252,323,915...252,383,682 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Cidofovir results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 6:49,425,316...49,462,109 JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of NARS1 mRNA CTD PMID:25596134 NCBI chr18:57,989,308...58,005,639 JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 affects expression ISO Cidofovir affects the expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,968,814...157,992,314 JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Cidofovir results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:23,289,793...23,468,026 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity
affects expression
ISO Cidofovir affects the activity of NFE2L2 protein
Cidofovir affects the expression of NFE2L2 mRNA
CTD PMID:25596134 NCBI chr 3:60,594,239...60,621,785 JBrowse link
G Nin ninein decreases expression ISO Cidofovir results in decreased expression of NIN mRNA CTD PMID:25596134 NCBI chr 6:88,525,405...88,627,710 JBrowse link
G Ninj1 ninjurin 1 increases expression ISO Cidofovir results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Cidofovir results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:35,295,633...35,310,528 JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO Cidofovir results in decreased expression of NR3C1 mRNA CTD PMID:25596134 NCBI chr18:31,271,681...31,393,320 JBrowse link
G Nrep neuronal regeneration related protein increases expression ISO Cidofovir results in increased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:25,017,069...25,046,564 JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO Cidofovir results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:53,701,496...53,715,260 JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression ISO Cidofovir affects the expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:47,471,750...47,500,517 JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial increases expression ISO Cidofovir results in increased expression of OXSM mRNA CTD PMID:25596134 NCBI chr15:9,210,443...9,215,852 JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Cidofovir results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:27,302,046...27,352,098 JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO Cidofovir results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:232,324,718...232,395,445 JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Cidofovir results in decreased expression of PDE8A mRNA CTD PMID:25596134 NCBI chr 1:135,166,143...135,288,986 JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Cidofovir results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087 JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Cidofovir results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 4:33,591,796...33,601,798 JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO Cidofovir results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:239,042,372...239,091,074 JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 affects expression ISO Cidofovir affects the expression of PFKFB4 mRNA CTD PMID:25596134 NCBI chr 8:109,643,558...109,687,006 JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects expression ISO Cidofovir affects the expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:185,906,964...185,936,160 JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Cidofovir results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:47,193,250...47,196,335 JBrowse link
G Pidd1 p53-induced death domain protein 1 affects expression ISO Cidofovir affects the expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:196,536,815...196,542,808 JBrowse link
G Pir pirin increases expression ISO Cidofovir results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269 JBrowse link
G Plec plectin decreases expression ISO Cidofovir results in decreased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:107,887,764...107,949,100 JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Cidofovir results in increased expression of PLK3 mRNA CTD PMID:25596134 NCBI chr 5:130,607,142...130,612,317 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 affects expression ISO Cidofovir affects the expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:59,986,187...59,990,174 JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression ISO Cidofovir results in increased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:162,011,884...162,060,137 JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 increases expression ISO Cidofovir results in increased expression of PNPLA6 mRNA CTD PMID:25596134 NCBI chr12:1,574,387...1,603,735 JBrowse link
G Podxl podocalyxin-like decreases expression ISO Cidofovir results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 4:60,135,124...60,181,829 JBrowse link
G Polr3f RNA polymerase III subunit F decreases expression ISO Cidofovir results in decreased expression of POLR3F mRNA CTD PMID:25596134 NCBI chr 3:131,908,466...131,924,838 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO Cidofovir affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Ppfibp1 PPFIA binding protein 1 increases expression ISO Cidofovir results in increased expression of PPFIBP1 mRNA CTD PMID:25596134 NCBI chr 4:179,807,579...179,951,428 JBrowse link
G Ppig peptidylprolyl isomerase G decreases expression ISO Cidofovir results in decreased expression of PPIG mRNA CTD PMID:25596134 NCBI chr 3:54,484,023...54,512,929 JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Cidofovir results in increased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 1:96,000,053...96,003,128 JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 decreases expression ISO Cidofovir results in decreased expression of PPP4R2 mRNA CTD PMID:25596134 NCBI chr 4:133,454,555...133,495,486 JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Cidofovir results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:134,250,086...134,271,765 JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO Cidofovir results in decreased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:47,959,858...47,981,488 JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO Cidofovir results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:185,257,218...185,272,846 JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 increases expression ISO Cidofovir results in increased expression of PRPS1 mRNA CTD PMID:25596134 NCBI chr  X:104,132,139...104,154,191 JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Cidofovir results in increased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:213,196,709...213,218,564 JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Cidofovir results in decreased expression of PSPC1 mRNA CTD PMID:25596134 NCBI chr15:30,828,617...30,911,315 JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Cidofovir results in increased expression of PYCR1 mRNA CTD PMID:25596134 NCBI chr10:105,917,732...105,922,658 JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression ISO Cidofovir results in increased expression of RAB26 mRNA CTD PMID:25596134 NCBI chr10:13,553,395...13,558,063 JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO Cidofovir results in increased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:105,246,712...105,382,973 JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Cidofovir results in increased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:83,883,490...83,928,932 JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Cidofovir results in increased expression of RFFL mRNA CTD PMID:25596134 NCBI chr10:67,740,711...67,803,694 JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO Cidofovir results in increased expression of RIT1 mRNA CTD PMID:25596134 NCBI chr 2:174,180,742...174,195,455 JBrowse link
G Rlf RLF zinc finger decreases expression ISO Cidofovir results in decreased expression of RLF mRNA CTD PMID:25596134 NCBI chr 5:134,711,612...134,767,274 JBrowse link
G Rnd1 Rho family GTPase 1 increases expression ISO Cidofovir results in increased expression of RND1 mRNA CTD PMID:25596134 NCBI chr 7:129,821,311...129,828,385 JBrowse link
G Rnd3 Rho family GTPase 3 affects expression ISO Cidofovir affects the expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:35,571,929...35,589,283 JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO Cidofovir results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:156,377,583...156,439,923 JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Cidofovir results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:55,499,514...55,520,504 JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Cidofovir results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:67,562,483...67,567,418 JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression ISO Cidofovir results in decreased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:69,077,024...69,108,742 JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 affects expression ISO Cidofovir affects the expression of RSL1D1 mRNA CTD PMID:25596134 NCBI chr10:4,424,868...4,436,753 JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression ISO Cidofovir results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:32,839,815...32,859,820 JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Cidofovir results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr11:31,839,880...32,074,427 JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Cidofovir results in increased expression of RUNX2 mRNA CTD PMID:25596134 NCBI chr 9:16,167,504...16,492,826 JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 2:196,065,543...196,081,240 JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 increases expression ISO Cidofovir results in increased expression of SDF2L1 mRNA CTD PMID:25596134 NCBI chr11:83,872,659...83,874,902 JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Cidofovir results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:22,985,557...23,005,756 JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Cidofovir results in increased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:82,775,692...82,778,961 JBrowse link
G Sesn1 sestrin 1 increases expression ISO Cidofovir results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698 JBrowse link
G Setx senataxin decreases expression ISO Cidofovir results in decreased expression of SETX mRNA CTD PMID:25596134 NCBI chr 3:12,428,091...12,480,801 JBrowse link
G Sfn stratifin increases expression ISO Cidofovir results in increased expression of SFN mRNA CTD PMID:25596134
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO Cidofovir results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:75,005,691...75,050,001 JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Cidofovir affects the expression of SHANK3 mRNA CTD PMID:25596134 NCBI chr 7:120,568,707...120,630,796 JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 affects expression ISO Cidofovir affects the expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:142,913,924...142,931,752 JBrowse link
G Sik1 salt-inducible kinase 1 affects expression ISO Cidofovir affects the expression of SIK1 mRNA CTD PMID:25596134 NCBI chr20:9,949,407...9,959,036 JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Cidofovir results in decreased expression of SIPA1L2 mRNA CTD PMID:25596134 NCBI chr19:53,389,792...53,540,466 JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Cidofovir results in increased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:131,705,312...131,709,697 JBrowse link
G Slc12a8 solute carrier family 12, member 8 affects expression ISO Cidofovir affects the expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:67,116,876...67,266,548 JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO Cidofovir results in increased expression of SLC1A4 mRNA CTD PMID:25596134 NCBI chr14:94,530,801...94,560,190 JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Cidofovir results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:77,456,849...77,470,952 JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases import
multiple interactions
increases response to substance
ISO SLC22A6 protein results in increased import of Cidofovir
SLC22A6 protein results in increased uptake of and results in increased susceptibility to Cidofovir
SLC22A6 protein results in increased susceptibility to Cidofovir
CTD PMID:23856525 PMID:25448811 PMID:29738843 NCBI chr 1:205,522,579...205,531,179 JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance ISO SLC22A8 protein results in increased susceptibility to Cidofovir CTD PMID:25448811 NCBI chr 1:205,496,331...205,516,378 JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO Cidofovir results in increased expression of SLC25A20 mRNA CTD PMID:25596134 NCBI chr 8:109,365,056...109,386,512 JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Cidofovir results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:113,804,728...113,842,208 JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Cidofovir results in increased expression of SLC2A1 mRNA CTD PMID:25596134 NCBI chr 5:132,717,196...132,745,416 JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cidofovir results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:205,604,468...205,618,931 JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression ISO Cidofovir affects the expression of SLC6A6 mRNA CTD PMID:25596134 NCBI chr 4:124,195,186...124,268,880 JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO Cidofovir results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:131,374,562...131,408,733 JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression ISO Cidofovir results in increased expression of SLC7A1 mRNA CTD PMID:25596134 NCBI chr12:6,628,214...6,703,849 JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Cidofovir results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:49,935,220...49,963,823 JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO Cidofovir results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294 JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO Cidofovir results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:26,250,178...26,342,151 JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Cidofovir results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:30,850,890...30,923,167 JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO Cidofovir results in decreased expression of SORL1 mRNA CTD PMID:25596134 NCBI chr 8:42,341,704...42,504,435 JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 affects expression ISO Cidofovir affects the expression of SPRY1 mRNA CTD PMID:25596134 NCBI chr 2:120,557,276...120,561,918 JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression ISO Cidofovir results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:32,046,415...32,060,796 JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Cidofovir results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:140,604,490...140,610,050 JBrowse link
G Strbp spermatid perinuclear RNA binding protein decreases expression ISO Cidofovir results in decreased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 3:21,328,310...21,467,753 JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Cidofovir results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:154,822,079...154,904,566 JBrowse link
G Taldo1 transaldolase 1 increases expression ISO Cidofovir results in increased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr 1:196,493,634...196,503,965 JBrowse link
G Taok1 TAO kinase 1 decreases expression ISO Cidofovir results in decreased expression of TAOK1 mRNA CTD PMID:25596134 NCBI chr10:62,373,076...62,465,295 JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Cidofovir results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:60,368,251...60,387,733 JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO Cidofovir results in increased expression of TBXAS1 mRNA CTD PMID:25596134 NCBI chr 4:67,664,963...67,837,096 JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Cidofovir results in decreased expression of TFAP2A mRNA CTD PMID:25596134 NCBI chr17:24,028,716...24,047,507 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Cidofovir results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,927,138...159,946,094 JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b affects expression ISO Cidofovir affects the expression of TIMM17B mRNA CTD PMID:25596134 NCBI chr  X:14,596,330...14,603,491 JBrowse link
G Tinag tubulointerstitial nephritis antigen decreases expression ISO Cidofovir results in decreased expression of TINAG mRNA CTD PMID:25596134 NCBI chr 8:77,800,031...77,885,077 JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Cidofovir results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327 JBrowse link
G Tmem45b transmembrane protein 45b decreases expression ISO Cidofovir results in decreased expression of TMEM45B mRNA CTD PMID:25596134 NCBI chr 8:29,865,276...29,910,453 JBrowse link
G Tmem94 transmembrane protein 94 decreases expression ISO Cidofovir results in decreased expression of TMEM94 mRNA CTD PMID:25596134 NCBI chr10:100,991,523...101,027,046 JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 decreases expression ISO Cidofovir results in decreased expression of TMTC2 mRNA CTD PMID:25596134 NCBI chr 7:40,392,377...40,806,685 JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Cidofovir results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:1,944,017...1,946,351 JBrowse link
G Top1 DNA topoisomerase I affects expression ISO Cidofovir affects the expression of TOP1 mRNA CTD PMID:25596134 NCBI chr 3:149,293,658...149,375,405 JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
ISO Cidofovir results in increased expression of TP53 protein
Cidofovir affects the activity of TP53 protein
CTD PMID:11697818 PMID:25596134 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Cidofovir results in increased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr13:69,612,605...69,655,018 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 affects expression ISO Cidofovir affects the expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,253,986...24,272,250 JBrowse link
G Tpcn1 two pore segment channel 1 increases expression ISO Cidofovir results in increased expression of TPCN1 mRNA CTD PMID:25596134 NCBI chr12:35,972,813...36,029,632 JBrowse link
G Tpd52l1 TPD52 like 1 affects expression ISO Cidofovir affects the expression of TPD52L1 mRNA CTD PMID:25596134 NCBI chr 1:26,172,038...26,290,704 JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression ISO Cidofovir results in increased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525 JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO Cidofovir results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:41,267,534...41,270,053 JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Cidofovir results in decreased expression of TSPAN12 mRNA CTD PMID:25596134 NCBI chr 4:50,313,768...50,389,246 JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Cidofovir results in increased expression of TXN mRNA CTD PMID:25596134 NCBI chr 5:72,712,334...72,724,564 JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Cidofovir results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:20,830,042...20,914,990 JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 increases expression ISO Cidofovir results in increased expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:10,983,734...11,005,468 JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O affects expression ISO Cidofovir affects the expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:101,765,572...101,812,736 JBrowse link
G Unkl unk like zinc finger affects expression ISO Cidofovir affects the expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,206,125...14,252,226 JBrowse link
G Usp3 ubiquitin specific peptidase 3 affects expression ISO Cidofovir affects the expression of USP3 mRNA CTD PMID:25596134 NCBI chr 8:67,078,249...67,154,109 JBrowse link
G Vegfb vascular endothelial growth factor B increases expression ISO Cidofovir results in increased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr 1:204,172,297...204,178,046 JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 increases expression ISO Cidofovir results in increased expression of VIPR1 mRNA CTD PMID:25596134 NCBI chr 8:121,303,739...121,339,587 JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 increases expression ISO Cidofovir results in increased expression of VTCN1 mRNA CTD PMID:25596134 NCBI chr 2:188,253,594...188,321,658 JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Cidofovir results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:127,776,088...127,807,273 JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO Cidofovir results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr16:44,258,372...44,421,815 JBrowse link
G Xbp1 X-box binding protein 1 affects activity
increases expression
ISO Cidofovir affects the activity of XBP1 protein
Cidofovir results in increased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr14:80,390,629...80,395,713 JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO Cidofovir results in increased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:123,993,670...124,020,922 JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 affects expression ISO Cidofovir affects the expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:141,535,815...141,564,029 JBrowse link
G Yeats2 YEATS domain containing 2 affects expression ISO Cidofovir affects the expression of YEATS2 mRNA CTD PMID:25596134 NCBI chr11:80,743,134...80,829,253 JBrowse link
G Ythdc2 YTH domain containing 2 decreases expression ISO Cidofovir results in decreased expression of YTHDC2 mRNA CTD PMID:25596134 NCBI chr18:37,266,559...37,331,681 JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Cidofovir results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:115,106,050...115,136,863 JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:175,718,808...175,737,128 JBrowse link
costunolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP costunolide results in increased activity of CAT protein CTD PMID:20709041 NCBI chr 3:89,842,393...89,874,577 JBrowse link
G Il10 interleukin 10 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 NCBI chr13:42,472,625...42,477,308 JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of NOS2 protein] CTD PMID:26970604 NCBI chr10:63,815,308...63,851,208 JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of PCNA protein] CTD PMID:26970604 NCBI chr 3:119,499,039...119,502,911 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of PTGS2 protein] CTD PMID:26970604 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:26970604 NCBI chr20:3,622,011...3,624,629 JBrowse link
delavirdine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238 JBrowse link
didanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Didanosine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:41,413,451...41,421,502 JBrowse link
G Il24 interleukin 24 decreases expression ISO Didanosine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487 JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression
multiple interactions
ISO Didanosine results in decreased expression of COX2 mRNA
tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA]
CTD PMID:16940060
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Didanosine CTD PMID:19164483 NCBI chr20:28,645,265...28,685,388 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Didanosine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457 JBrowse link
efavirenz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO efavirenz inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
efavirenz results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
decreases secretion
ISO efavirenz results in decreased expression of ADIPOQ mRNA
efavirenz results in decreased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:77,721,912...77,735,644 JBrowse link
G Alb albumin affects binding ISO efavirenz binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Bcl2l11 BCL2 like 11 increases response to substance
increases expression
ISO BCL2L11 protein results in increased susceptibility to efavirenz metabolite
efavirenz metabolite results in increased expression of BCL2L11 mRNA; efavirenz metabolite results in increased expression of BCL2L11 protein; efavirenz results in increased expression of BCL2L11 mRNA; efavirenz results in increased expression of BCL2L11 protein
CTD PMID:21958719 NCBI chr 3:115,366,783...115,404,068 JBrowse link
G Canx calnexin affects localization ISO efavirenz affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:34,623,865...34,656,866 JBrowse link
G Casp3 caspase 3 multiple interactions ISO efavirenz metabolite results in increased cleavage of and results in increased activity of CASP3 protein; efavirenz results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:21958719 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO efavirenz results in increased secretion of CCL2 protein CTD PMID:21619898 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO efavirenz results in decreased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:87,759,631...87,762,303 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
decreases activity
multiple interactions
increases metabolic processing
ISO CYP2B6 gene polymorphism affects the metabolism of efavirenz; CYP2B6 protein affects the metabolism of efavirenz
efavirenz results in decreased activity of CYP2B6 protein
[efavirenz results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion; [efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in increased metabolism of efavirenz
CTD PMID:15622315 PMID:15769884 PMID:17041008 PMID:17559344 PMID:26599973 NCBI chr 1:81,652,762...81,732,153 JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO efavirenz results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO efavirenz results in increased expression of DDIT3 protein CTD PMID:28940366 NCBI chr 7:63,115,645...63,121,203 JBrowse link
G Dnm1l dynamin 1-like affects localization ISO efavirenz affects the localization of DNM1L protein modified form CTD PMID:28940366 NCBI chr11:84,581,216...84,632,382 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO efavirenz results in increased expression of EIF2AK3 protein modified form CTD PMID:28940366 NCBI chr 4:102,805,495...102,866,914 JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO efavirenz results in increased expression of FIS1 mRNA CTD PMID:28940366 NCBI chr12:19,708,558...19,723,392 JBrowse link
G Hgf hepatocyte growth factor increases secretion ISO efavirenz results in increased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:18,673,736...18,745,582 JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr18:26,536,131...26,554,294 JBrowse link
G Il6 interleukin 6 increases secretion ISO efavirenz results in increased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:5,214,602...5,219,178 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of JUN protein; efavirenz results in increased phosphorylation of JUN protein CTD PMID:21958719 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Lep leptin decreases expression ISO efavirenz results in decreased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:57,661,127...57,675,262 JBrowse link
G Lonp1 lon peptidase 1, mitochondrial multiple interactions
increases expression
increases response to substance
ISO efavirenz results in increased expression of and affects the localization of LONP1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [efavirenz results in increased expression of LONP1 mRNA]
LONP1 protein results in increased susceptibility to efavirenz
CTD PMID:28940366 NCBI chr 9:1,447,444...1,459,771 JBrowse link
G Lpl lipoprotein lipase decreases expression ISO efavirenz results in decreased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:20,830,055...20,853,855 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of MAP3K5 protein; efavirenz results in increased phosphorylation of MAP3K5 protein CTD PMID:21958719 NCBI chr 1:14,685,776...14,904,935 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]
efavirenz metabolite results in increased phosphorylation of MAPK8 protein; efavirenz results in increased phosphorylation of MAPK8 protein
CTD PMID:21958719 NCBI chr16:8,638,897...8,721,960 JBrowse link
G Mfn2 mitofusin 2 increases expression ISO efavirenz results in increased expression of MFN2 mRNA CTD PMID:28940366 NCBI chr 5:158,304,285...158,335,502 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity EXP efavirenz results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr11:62,460,213...62,496,665 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity
ISO
EXP
[efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 PMID:27732639 NCBI chr13:83,632,940...83,638,193 JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression ISO efavirenz results in increased expression of OPA1 mRNA CTD PMID:28940366 NCBI chr11:71,108,100...71,185,170 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO efavirenz results in decreased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:148,423,102...148,548,471 JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 increases expression ISO efavirenz results in increased expression of RMDN3 protein CTD PMID:28940366 NCBI chr 3:106,125,961...106,146,568 JBrowse link
G Serpine1 serpin family E member 1 increases secretion ISO efavirenz results in increased secretion of SERPINE1 protein CTD PMID:21619898 NCBI chr12:19,601,272...19,611,657 JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:18,546,709...18,556,698 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 NCBI chr10:45,007,637...45,029,650 JBrowse link
G Tg thyroglobulin increases expression ISO efavirenz results in increased expression of TG mRNA; efavirenz results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:98,418,293...98,603,210 JBrowse link
G Tpo thyroid peroxidase increases expression ISO efavirenz results in increased expression of TPO mRNA; efavirenz results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:46,698,402...46,768,199 JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein; efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:190,224,676...190,229,559 JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO efavirenz results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:110,341,585...110,475,297 JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr10:36,532,306...36,559,642 JBrowse link
emtricitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Emtricitabine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Dck deoxycytidine kinase multiple interactions
affects binding
ISO DCK protein results in increased phosphorylation of and results in increased activity of Emtricitabine
Emtricitabine binds to DCK protein
CTD PMID:17530837 NCBI chr14:19,305,218...19,326,247 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions
ISO Emtricitabine results in decreased expression of PRKN protein
[Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein
CTD PMID:31545371 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein CTD PMID:31545371 NCBI chr10:54,300,070...54,311,525 JBrowse link
enfuvirtide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects activity ISO enfuvirtide affects the activity of CYP1A2 protein CTD PMID:15656696 NCBI chr 8:58,075,367...58,082,255 JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 affects activity ISO enfuvirtide affects the activity of CYP2C19 protein CTD PMID:15656696 NCBI chr 1:237,938,521...237,976,238 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects activity ISO enfuvirtide affects the activity of CYP2E1 protein CTD PMID:15656696 NCBI chr 1:195,840,330...195,850,728 JBrowse link
floxuridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
decreases response to substance
ISO APEX1 protein mutant form results in increased susceptibility to Floxuridine
APEX1 protein results in decreased susceptibility to Floxuridine
CTD PMID:19470598 PMID:22194930 NCBI chr15:24,144,595...24,146,785 JBrowse link
G Atr ATR serine/threonine kinase decreases response to substance ISO ATR protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 8:96,426,704...96,524,152 JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Floxuridine CTD PMID:25354864 NCBI chr10:55,699,954...55,704,605 JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK1 protein CTD PMID:21613406 PMID:22194930 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases activity
ISO Floxuridine results in increased phosphorylation of and results in increased activity of CHEK2 protein
Floxuridine results in increased activity of CHEK2 protein
CTD PMID:21613406 PMID:22194930 NCBI chr12:45,788,823...45,821,382 JBrowse link
G Mlh1 mutL homolog 1 multiple interactions
decreases response to substance
ISO olaparib inhibits the reaction [MLH1 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 8:111,196,468...111,233,721 JBrowse link
G Msh2 mutS homolog 2 multiple interactions
decreases response to substance
ISO olaparib inhibits the reaction [MSH2 protein results in decreased susceptibility to Floxuridine] CTD PMID:22194930 NCBI chr 6:6,813,793...6,872,960 JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR protein affects the susceptibility to Floxuridine CTD PMID:18202788 NCBI chr 5:158,465,248...158,484,999 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases response to substance ISO PARP1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 affects response to substance
decreases response to substance
ISO TIMP3 protein affects the susceptibility to Floxuridine
TIMP3 gene modified form results in decreased susceptibility to Floxuridine
CTD PMID:18202788 NCBI chr 7:17,520,827...17,571,871 JBrowse link
G Tk1 thymidine kinase 1 increases expression ISO Floxuridine results in increased expression of TK1 protein CTD PMID:16951200 NCBI chr10:103,034,755...103,046,125 JBrowse link
G Tp53 tumor protein p53 increases expression ISO Floxuridine results in increased expression of TP53 protein CTD PMID:19015155 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Tyms thymidylate synthetase affects response to substance
increases response to substance
decreases response to substance
ISO TYMS protein affects the susceptibility to Floxuridine
TYMS results in increased susceptibility to Floxuridine
TYMS protein results in decreased susceptibility to Floxuridine
CTD PMID:2537495 PMID:10482907 PMID:15040806 PMID:17018589 NCBI chr 9:113,313,454...113,329,551 JBrowse link
G Ung uracil-DNA glycosylase affects expression
increases response to substance
affects stability
ISO Floxuridine affects the expression of UNG mRNA; Floxuridine affects the expression of UNG protein
UNG protein results in increased susceptibility to Floxuridine
Floxuridine affects the stability of UNG protein alternative form
CTD PMID:16951200 NCBI chr12:42,485,276...42,494,217 JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases response to substance ISO XRCC1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PMID:22194930 NCBI chr 1:80,140,495...80,168,705 JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Floxuridine CTD PMID:21785230 NCBI chr 2:20,948,464...21,197,705 JBrowse link
ganciclovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Ganciclovir results in decreased expression of BCL2 protein CTD PMID:15592511 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Ganciclovir results in increased expression of MDM2 protein CTD PMID:15592511 NCBI chr 7:53,290,660...53,315,205 JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
ISO Ganciclovir results in increased secretion of TNF protein
Sulfasalazine promotes the reaction [Ganciclovir results in increased secretion of TNF protein]
CTD PMID:17143539 NCBI chr20:3,622,011...3,624,629 JBrowse link
G Tp53 tumor protein p53 increases expression ISO Ganciclovir results in increased expression of TP53 protein CTD PMID:15592511 NCBI chr10:54,300,070...54,311,525 JBrowse link
gemcitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO gemcitabine results in increased expression of A2M protein CTD PMID:20531411 NCBI chr 4:154,897,770...154,947,787 JBrowse link
G Acp3 acid phosphatase 3 decreases expression ISO gemcitabine results in decreased expression of ACP3 protein CTD PMID:20531411 NCBI chr 8:104,905,570...104,956,146 JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO ADAM17 protein promotes the reaction [gemcitabine results in increased cleavage of AREG protein] CTD PMID:20726858 NCBI chr 6:40,872,936...40,920,700 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO gemcitabine results in increased expression of ADIPOQ protein CTD PMID:20531411 NCBI chr11:77,721,912...77,735,644 JBrowse link
G Afp alpha-fetoprotein decreases expression ISO gemcitabine results in decreased expression of AFP protein CTD PMID:20531411 NCBI chr14:17,573,412...17,591,476 JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 decreases expression ISO gemcitabine results in decreased expression of AGPAT2 mRNA CTD PMID:17039268 NCBI chr 3:9,416,842...9,428,567 JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects response to substance
multiple interactions
ISO AKT1 protein affects the susceptibility to gemcitabine
[gemcitabine co-treated with licoricidin] results in decreased phosphorylation of AKT1 protein; [licoricidin co-treated with gemcitabine] results in decreased phosphorylation of AKT1 protein
CTD PMID:15867245 PMID:29782821 NCBI chr 6:131,713,716...131,735,319 JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression
multiple interactions
ISO gemcitabine results in decreased expression of ALDH1A1 protein
sulforaphane promotes the reaction [gemcitabine results in decreased expression of ALDH1A1 protein]
CTD PMID:20940707 NCBI chr 1:218,000,470...218,152,962 JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO gemcitabine results in increased expression of ALDH1A3 mRNA CTD PMID:17039268 NCBI chr 1:119,982,272...120,017,416 JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO gemcitabine results in increased expression of ALDH6A1 mRNA CTD PMID:17039268 NCBI chr 6:104,077,975...104,098,636 JBrowse link
G Anapc1 anaphase promoting complex subunit 1 increases expression ISO gemcitabine results in increased expression of ANAPC1 mRNA CTD PMID:17039268 NCBI chr 3:115,850,117...115,930,259 JBrowse link
G Ank3 ankyrin 3 increases expression ISO gemcitabine results in increased expression of ANK3 mRNA CTD PMID:17039268 NCBI chr20:18,602,267...19,225,831 JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO gemcitabine results in increased expression of ANKRD1 mRNA CTD PMID:17039268 NCBI chr 1:233,815,851...233,834,891 JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 affects expression ISO gemcitabine affects the expression of ANTXR1 mRNA CTD PMID:17039268 NCBI chr 4:119,590,770...119,778,232 JBrowse link
G Apcs amyloid P component, serum decreases expression ISO gemcitabine results in decreased expression of APCS protein CTD PMID:20531411 NCBI chr13:85,373,338...85,374,134 JBrowse link
G Apoh apolipoprotein H increases expression ISO gemcitabine results in increased expression of APOH protein CTD PMID:20531411 NCBI chr10:93,342,435...93,356,334 JBrowse link
G Ar androgen receptor multiple interactions ISO gemcitabine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934 JBrowse link
G Areg amphiregulin multiple interactions
increases expression
increases cleavage
decreases response to substance
ISO ADAM17 protein promotes the reaction [gemcitabine results in increased cleavage of AREG protein]
gemcitabine results in increased expression of AREG protein
AREG protein results in decreased susceptibility to gemcitabine
CTD PMID:20726858 NCBI chr14:16,972,185...16,981,443 JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression ISO gemcitabine results in decreased expression of ARF1 mRNA CTD PMID:17039268 NCBI chr10:43,997,983...44,014,543 JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO gemcitabine results in increased expression of ARNT mRNA CTD PMID:20103597 NCBI chr 2:182,997,731...183,056,584 JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO gemcitabine results in increased expression of ATF3 mRNA CTD PMID:17039268 NCBI chr13:102,751,278...102,800,520 JBrowse link
G Axin2 axin 2 affects expression ISO gemcitabine affects the expression of AXIN2 mRNA CTD PMID:20103597 NCBI chr10:93,893,830...93,927,042 JBrowse link
G Axl Axl receptor tyrosine kinase multiple interactions ISO AXL protein promotes the reaction [Warfarin results in increased susceptibility to gemcitabine] CTD PMID:26206560 NCBI chr 1:81,265,656...81,296,278 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [alvocidib co-treated with gemcitabine] results in increased expression of BAX protein; [ICI 118551 co-treated with gemcitabine] results in increased expression of BAX protein; [Mastic Resin co-treated with gemcitabine] results in increased expression of BAX protein; [TNFSF10 co-treated with gemcitabine] affects the localization of BAX protein CTD PMID:15770523 PMID:17671697 PMID:20523344 PMID:21570961 NCBI chr 1:95,940,001...95,945,407 JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO gemcitabine results in decreased expression of BCL2 protein
[alvocidib co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Aminophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein; [ICI 118551 co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Mastic Resin co-treated with gemcitabine] results in decreased expression of BCL2 protein; [Theophylline co-treated with gemcitabine] results in decreased expression of BCL2 protein; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [gemcitabine results in decreased expression of BCL2 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BCL2 protein
CTD PMID:15476743 PMID:15645133 PMID:15770523 PMID:16929163 PMID:17440100 PMID:20523344 PMID:21570961 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 mRNA]; gemcitabine inhibits the reaction [Fluorouracil affects the expression of BCL2L1 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BCL2L1 protein
gemcitabine results in decreased expression of BCL2L1 protein
CTD PMID:15476743 PMID:16929163 PMID:17440100 NCBI chr 3:141,253,508...141,304,582 JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO gemcitabine results in increased expression of BCL2L11 mRNA CTD PMID:17039268 NCBI chr 3:115,366,783...115,404,068 JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO gemcitabine results in increased expression of BCL6 mRNA CTD PMID:17039268 NCBI chr11:76,854,090...76,877,389 JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression ISO gemcitabine results in decreased expression of BDNF protein CTD PMID:20531411 NCBI chr 3:96,165,042...96,215,621 JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage ISO gemcitabine results in increased cleavage of BID protein CTD PMID:14750167 NCBI chr 4:154,113,198...154,136,353 JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO gemcitabine results in increased expression of BIRC2 mRNA CTD PMID:17039268 NCBI chr 8:4,968,856...4,989,325 JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects expression
multiple interactions
ISO gemcitabine affects the expression of BIRC3 mRNA
[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC3 protein
CTD PMID:17039268 PMID:17440100 NCBI chr 8:5,000,844...5,028,470 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 mRNA]; gemcitabine inhibits the reaction [Fluorouracil results in decreased expression of BIRC5 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of BIRC5 protein
CTD PMID:16929163 PMID:17440100 NCBI chr10:103,072,530...103,081,382 JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO gemcitabine results in increased expression of BNIP3L mRNA CTD PMID:17039268 NCBI chr15:41,174,594...41,197,730 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO gemcitabine results in decreased expression of BRAF mRNA CTD PMID:20103597 NCBI chr 4:68,375,484...68,510,652 JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
decreases response to substance
ISO gemcitabine results in increased expression of BRCA1 mRNA
BRCA1 results in decreased susceptibility to gemcitabine
CTD PMID:20103597 PMID:21771338 NCBI chr10:86,417,441...86,477,762 JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
increases cleavage
ISO gemcitabine results in increased activity of CASP3 protein
gemcitabine results in increased expression of CASP3 protein modified form
[10-propargyl-10-deazaaminopterin co-treated with gemcitabine] results in increased activity of CASP3 protein; [Curcumin co-treated with gemcitabine] results in decreased expression of CASP3 protein
gemcitabine results in increased cleavage of CASP3 protein
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with gemcitabine] affects the activity of CASP3 protein; [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with gemcitabine] affects the activity of CASP3 protein; [alvocidib co-treated with gemcitabine] results in increased cleavage of CASP3 protein; [Calcitriol co-treated with gemcitabine] results in increased expression of CASP3 protein; [gemcitabine co-treated with TNFRSF10B] affects the activity of CASP3 protein; [vorinostat co-treated with gemcitabine] results in increased activity of CASP3 protein; gemcitabine results in increased expression of and results in increased activity of CASP3 protein; licoricidin promotes the reaction [gemcitabine results in increased activity of CASP3 protein]; licoricidin promotes the reaction [gemcitabine results in increased expression of and results in increased activity of CASP3 protein]; Quercetin promotes the reaction [gemcitabine results in increased activity of CASP3 protein]; SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP3 protein]
CTD PMID:12479703 PMID:15476743 PMID:15726400 PMID:15770523 PMID:16153448 PMID:16467107 PMID:17159604 PMID:17440100 PMID:18089714 PMID:20299819 PMID:20699664 PMID:20798217 PMID:21418860 PMID:26050647 PMID:29782821 NCBI chr16:45,662,910...45,681,171 JBrowse link
G Casp6 caspase 6 multiple interactions ISO [Calcitriol co-treated with gemcitabine] results in increased expression of CASP6 protein CTD PMID:20699664 NCBI chr 2:218,466,063...218,478,503 JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases activity
ISO [Calcitriol co-treated with gemcitabine] results in increased expression of CASP8 protein; [gemcitabine co-treated with TNFRSF10B] affects the activity of CASP8 protein; [TNFSF10 co-treated with gemcitabine] results in increased activity of CASP8 protein; gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein; SFN protein inhibits the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]; YAP1 protein affects the reaction [gemcitabine results in increased activity of and results in increased cleavage of CASP8 protein]
gemcitabine results in increased cleavage of CASP8 protein
gemcitabine results in increased activity of CASP8 protein
CTD PMID:12479703 PMID:14750167 PMID:17159604 PMID:17671697 PMID:18089714 PMID:20699664 PMID:26894857 NCBI chr 9:60,263,863...60,312,542 JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
ISO [Calcitriol co-treated with gemcitabine] results in increased expression of CASP9 protein; Quercetin promotes the reaction [gemcitabine results in increased activity of CASP9 protein]; SMG1 protein inhibits the reaction [gemcitabine results in increased activity of CASP9 protein]
[Curcumin co-treated with gemcitabine] results in decreased expression of CASP9 protein
gemcitabine results in increased cleavage of CASP9 protein
CTD PMID:12479703 PMID:15476743 PMID:15726400 PMID:17159604 PMID:17440100 PMID:20699664 PMID:21418860 PMID:26050647 NCBI chr 5:154,108,872...154,126,628 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO gemcitabine results in decreased expression of CCL2 protein CTD PMID:20531411 NCBI chr10:67,005,424...67,007,222 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO gemcitabine results in increased expression of CCL20 mRNA CTD PMID:17039268 NCBI chr 9:84,389,031...84,391,629 JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO gemcitabine results in increased expression of CCL3 protein CTD PMID:20531411 NCBI chr10:68,451,388...68,452,938 JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
ISO gemcitabine results in decreased expression of CCNB1 mRNA
gemcitabine results in increased expression of CCNB1 protein
CTD PMID:11504793 PMID:20103597 NCBI chr 2:31,912,190...31,921,163 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO Celecoxib promotes the reaction [gemcitabine results in decreased expression of CCND1 protein]
gemcitabine results in decreased expression of CCND1 mRNA; gemcitabine results in decreased expression of CCND1 protein
[Curcumin co-treated with gemcitabine] results in decreased expression of CCND1 protein
CTD PMID:16060994 PMID:17039268 PMID:17440100 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Ccng2 cyclin G2 increases expression ISO gemcitabine results in increased expression of CCNG2 mRNA CTD PMID:17039268 NCBI chr14:14,804,321...14,812,819 JBrowse link
G Cd40 CD40 molecule decreases expression ISO gemcitabine results in decreased expression of CD40 mRNA; gemcitabine results in decreased expression of CD40 protein CTD PMID:17039268 PMID:20531411 NCBI chr 3:153,790,372...153,805,279 JBrowse link
G Cd40lg CD40 ligand decreases expression ISO gemcitabine results in decreased expression of CD40LG protein CTD PMID:20531411 NCBI chr  X:135,127,119...135,138,302 JBrowse link
G Cda cytidine deaminase affects response to substance
multiple interactions
ISO CDA protein affects the susceptibility to gemcitabine
[crizotinib results in decreased expression of CDA protein] which results in increased susceptibility to gemcitabine; CDA protein affects the susceptibility to [gemcitabine co-treated with Mitomycin]; CDA protein affects the susceptibility to [gemcitabine co-treated with oxaliplatin]
CTD PMID:18728667 PMID:22973962 NCBI chr 5:150,556,615...150,583,231 JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [gemcitabine co-treated with ON 01910] results in decreased expression of CDC25C protein CTD PMID:20103597 NCBI chr18:26,335,156...26,356,199 JBrowse link
G Cdh1 cadherin 1 increases expression ISO gemcitabine results in increased expression of CDH1 mRNA CTD PMID:17039268 NCBI chr19:34,492,371...34,561,775 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [alvocidib co-treated with gemcitabine] results in increased expression of CDKN1A protein; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of CDKN1A protein; Nicotine inhibits the reaction [gemcitabine results in increased expression of CDKN1A protein]
gemcitabine results in increased expression of CDKN1A mRNA; gemcitabine results in increased expression of CDKN1A protein
CTD PMID:15476743 PMID:15770523 PMID:16601104 PMID:17039268 PMID:25189999 NCBI chr20:7,149,177...7,159,727 JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases response to substance ISO CDKN1B results in decreased susceptibility to gemcitabine CTD PMID:21652059 NCBI chr 4:167,760,067...167,765,177 JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO gemcitabine results in increased expression of CEBPB mRNA CTD PMID:17039268 NCBI chr 3:156,398,035...156,399,466 JBrowse link
G Chrdl2 chordin-like 2 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of CHRDL2 protein CTD PMID:24979617 NCBI chr 1:154,343,201...154,370,651 JBrowse link
G Ckb creatine kinase B decreases expression ISO gemcitabine results in decreased expression of CKB mRNA CTD PMID:17039268 NCBI chr 6:130,729,420...130,732,301 JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO gemcitabine results in increased expression of CLIC4 mRNA CTD PMID:17039268 NCBI chr 5:147,456,819...147,513,278 JBrowse link
G Clu clusterin affects response to substance
increases expression
ISO CLU protein affects the susceptibility to gemcitabine
gemcitabine results in increased expression of CLU protein
CTD PMID:19007378 NCBI chr15:40,161,068...40,200,315 JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression
ISO BAY 11-7085 inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 5:48,408,543...48,436,099 JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
increases expression
ISO BAY 11-7085 inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 5:148,125,222...148,151,548 JBrowse link
G Csf2 colony stimulating factor 2 decreases expression ISO gemcitabine results in decreased expression of CSF2 protein CTD PMID:20531411 NCBI chr10:38,386,945...38,388,926 JBrowse link
G Csf3 colony stimulating factor 3 decreases expression ISO gemcitabine results in decreased expression of CSF3 protein CTD PMID:20531411 NCBI chr10:83,660,787...83,664,569 JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO gemcitabine results in increased expression of CSRP2 mRNA CTD PMID:17039268 NCBI chr 7:46,349,109...46,367,743 JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression ISO gemcitabine results in increased expression of CTHRC1 mRNA CTD PMID:17039268 NCBI chr 7:70,122,474...70,132,756 JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO gemcitabine results in increased expression of CTNNB1 mRNA CTD PMID:25605917 NCBI chr 8:120,640,008...120,667,110 JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO gemcitabine results in increased expression of CXCL1 mRNA CTD PMID:17039268 NCBI chr14:17,193,364...17,195,143 JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of CXCL11 protein CTD PMID:24979617 NCBI chr14:15,689,432...15,692,207 JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO gemcitabine results in increased expression of CXCL2 mRNA CTD PMID:17039268 NCBI chr14:17,181,030...17,183,075 JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO gemcitabine results in increased expression of CXCL1 mRNA CTD PMID:17039268 NCBI chr14:17,270,146...17,289,458 JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects expression ISO gemcitabine affects the expression of CXCR4 mRNA CTD PMID:20103597 NCBI chr13:40,077,976...40,081,883 JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression ISO gemcitabine results in decreased expression of CYP24A1 mRNA CTD PMID:17039268 NCBI chr 3:159,275,947...159,290,383 JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects expression ISO gemcitabine affects the expression of DDIT4 mRNA CTD PMID:17039268 NCBI chr20:27,891,989...27,894,088 JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO gemcitabine results in decreased expression of DHX9 mRNA CTD PMID:17039268 NCBI chr13:65,602,322...65,639,098 JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO gemcitabine results in increased expression of DLG2 mRNA CTD PMID:17039268 NCBI chr 1:144,451,653...146,503,949 JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [DNMT1 protein binds to SFN promoter] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; [gemcitabine results in decreased susceptibility to gemcitabine] inhibits the reaction [DNMT1 protein binds to SFN promoter]; [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of DNMT1 protein; [UHRF1 protein promotes the reaction [DNMT1 protein binds to SFN promoter]] inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine]; DNMT1 protein inhibits the reaction [gemcitabine results in decreased susceptibility to gemcitabine] CTD PMID:25189999 NCBI chr 8:19,440,611...19,486,659 JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of DNMT3B protein CTD PMID:25189999 NCBI chr 3:142,130,592...142,169,124 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions ISO [TYMP protein co-treated with DPYD protein] affects the susceptibility to gemcitabine CTD PMID:18728667 NCBI chr 2:206,609,043...207,474,982 JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 decreases expression ISO gemcitabine results in decreased expression of DYNC1H1 mRNA CTD PMID:17039268 NCBI chr 6:129,615,208...129,680,888 JBrowse link
G Edn1 endothelin 1 decreases expression ISO gemcitabine results in decreased expression of EDN1 protein CTD PMID:20531411 NCBI chr17:22,454,924...22,460,812 JBrowse link
G Edn2 endothelin 2 decreases expression ISO gemcitabine results in decreased expression of EDN2 mRNA CTD PMID:17039268 NCBI chr 5:133,751,316...133,756,814 JBrowse link
G Egf epidermal growth factor multiple interactions
decreases expression
ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]; Erlotinib Hydrochloride inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; pyrazolanthrone inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]; U 0126 inhibits the reaction [EGF promotes the reaction [TGFB1 results in decreased susceptibility to gemcitabine]]
gemcitabine results in decreased expression of EGF protein
CTD PMID:20531411 PMID:21613822 NCBI chr 2:218,219,408...218,302,370 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
increases expression
decreases expression
increases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; EGFR gene mutant form results in increased susceptibility to [gemcitabine co-treated with Cisplatin co-treated with Erlotinib Hydrochloride]; Gefitinib inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; gemcitabine promotes the reaction [HER3 protein binds to EGFR protein]
gemcitabine results in increased phosphorylation of EGFR protein
gemcitabine results in increased expression of EGFR mRNA
gemcitabine results in decreased expression of EGFR mRNA; gemcitabine results in decreased expression of EGFR protein
gemcitabine results in increased degradation of EGFR protein
CTD PMID:17146438 PMID:20103597 PMID:20726858 PMID:21541241 NCBI chr14:91,176,931...91,349,722 JBrowse link
G Egr1 early growth response 1 increases expression ISO gemcitabine results in increased expression of EGR1 mRNA CTD PMID:17039268 NCBI chr18:26,463,333...26,465,531 JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO gemcitabine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104 JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO gemcitabine results in increased expression of ETV1 mRNA CTD PMID:17039268 NCBI chr 6:55,590,149...55,681,784 JBrowse link
G Evi2b ecotropic viral integration site 2B decreases expression ISO gemcitabine results in decreased expression of EVI2B mRNA CTD PMID:17039268 NCBI chr10:64,472,693...64,474,311 JBrowse link
G F7 coagulation factor VII decreases expression ISO gemcitabine results in decreased expression of F7 protein CTD PMID:20531411 NCBI chr16:76,489,779...76,500,636 JBrowse link
G Fas Fas cell surface death receptor increases expression ISO gemcitabine results in increased expression of FAS mRNA; gemcitabine results in increased expression of FAS protein CTD PMID:11138460 PMID:17159604 NCBI chr 1:231,798,963...231,832,591 JBrowse link
G Fbxo25 F-box protein 25 increases expression ISO gemcitabine results in increased expression of FBXO25 mRNA CTD PMID:17039268 NCBI chr16:75,666,062...75,701,770 JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
increases expression
ISO [gemcitabine co-treated with IFNA2 protein] results in increased expression of FGF2 protein
gemcitabine results in increased expression of FGF2 protein
CTD PMID:12738744 PMID:20531411 NCBI chr 2:120,236,328...120,290,673 JBrowse link
G Fgg fibrinogen gamma chain affects expression ISO gemcitabine affects the expression of FGG mRNA CTD PMID:17039268 NCBI chr 2:168,354,880...168,362,325 JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit decreases expression ISO gemcitabine results in decreased expression of FOSL2 mRNA CTD PMID:17039268 NCBI chr 6:24,297,898...24,319,157 JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 increases expression ISO gemcitabine results in increased expression of FXYD3 mRNA CTD PMID:17039268 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO gemcitabine results in decreased expression of GAL3ST1 mRNA CTD PMID:17039268 NCBI chr14:78,868,049...78,886,402 JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO gemcitabine results in decreased expression of GAS1 mRNA CTD PMID:17039268 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO gemcitabine results in decreased expression of GASK1B mRNA CTD PMID:17039268 NCBI chr 2:165,047,689...165,112,479 JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 NCBI chr16:18,805,312...18,807,893 JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects response to substance ISO GIPC1 affects the susceptibility to gemcitabine CTD PMID:25469510 NCBI chr19:24,474,291...24,487,083 JBrowse link
G Gli2 GLI family zinc finger 2 affects expression ISO gemcitabine affects the expression of GLI2 mRNA CTD PMID:20103597 NCBI chr13:29,946,809...30,163,901 JBrowse link
G Glrx glutaredoxin increases expression ISO gemcitabine results in increased expression of GLRX mRNA CTD PMID:17039268 NCBI chr 2:5,341,873...5,351,686 JBrowse link
G Gpc3 glypican 3 increases expression ISO gemcitabine results in increased expression of GPC3 mRNA CTD PMID:17039268 NCBI chr  X:131,868,983...132,236,837 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO gemcitabine results in increased phosphorylation of GSK3B protein CTD PMID:16570353 NCBI chr11:62,498,997...62,648,665 JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 affects expression ISO gemcitabine affects the expression of GTF2A1 mRNA CTD PMID:17039268 NCBI chr 6:110,488,891...110,521,059 JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO gemcitabine results in decreased expression of H4C3 mRNA CTD PMID:17039268
G Hdac9 histone deacetylase 9 increases expression ISO gemcitabine results in increased expression of HDAC9 mRNA CTD PMID:17039268 NCBI chr 6:50,762,074...51,624,311 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects response to substance ISO HIF1A protein affects the susceptibility to gemcitabine CTD PMID:16628086 NCBI chr 6:92,624,059...92,669,262 JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO gemcitabine results in decreased expression of H4C2 mRNA CTD PMID:17039268 NCBI chr 2:183,831,601...183,831,996 JBrowse link
G Hoxb2 homeobox B2 increases expression ISO gemcitabine results in increased expression of HOXB2 mRNA CTD PMID:17039268 NCBI chr