Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Intestinal Ischemia
go back to main search page
Accession:DOID:9004663 term browser browse the term
Definition:A hypoperfusion of the blood through the intestine caused by a pathologic constriction or obstruction of its blood vessels, or an absence of blood circulation.
Synonyms:exact_synonym: intestine ischemia


show annotations for term's descendants           Sort by:
Intestinal Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin ISO protein:decreased expression:plasma RGD PMID:17263982 RGD:7364988 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G CFH complement factor H ISO protein:decreased expression:plasma RGD PMID:17263982 RGD:7364988 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G GCH1 GTP cyclohydrolase 1 ISO associated with Experimental Radiation Injuries;mRNA,protein:decreased expression:mesenteric artery RGD PMID:32562786 RGD:329961328 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G NPY neuropeptide Y ISO associated with Brain Injuries;mRNA, protein:increased expression:jejunum, plasma RGD PMID:23622727 RGD:10448970 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
Intestinal Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:15001561 RGD:13515113 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G AGT angiotensinogen ISO protein:increased expression:plasma RGD PMID:15001561 RGD:13515113 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AHR aryl hydrocarbon receptor treatment ISO RGD PMID:22079846 RGD:401794136 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta treatment ISO RGD PMID:24232000 RGD:13792678 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:23946597 RGD:13782356 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:23946597 RGD:13782356 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA:increased expression:small intestine RGD PMID:18475188 RGD:2307016 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CD14 CD14 molecule ISO protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CLDN1 claudin 1 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446 		JBrowse link
G CLDN3 claudin 3 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr 7:73,768,997...73,770,270
Ensembl chr 7:73,768,997...73,770,270 		JBrowse link
G CLDN5 claudin 5 ISO protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545 		JBrowse link
G CRP C-reactive protein ISO protein:increased expression:intestine: RGD PMID:17981193 RGD:5129536 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:9117128 RGD:11039476 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 treatment ISO RGD PMID:22079846 RGD:401794136 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G F7 coagulation factor VII IMP human protein in a rat model RGD PMID:22920553 RGD:11041662 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G FASLG Fas ligand treatment ISO RGD PMID:29170412 RGD:13792603 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G GPT glutamic--pyruvic transaminase ISO protein:increased expression:serum RGD PMID:16557159 RGD:401717563 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G HMGB1 high mobility group box 1 ISO RGD PMID:22093738 RGD:10402181 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:19362701 RGD:10766423 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin treatment ISO RGD PMID:11922743 RGD:11041790 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:12095141 PMID:22079846 RGD:11522715, RGD:401794136 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:11959089 PMID:22079846 RGD:11062110, RGD:401794136 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:22777122 RGD:10403072 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G LBP lipopolysaccharide binding protein ISO protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G MBL2 mannose binding lectin 2 severity IAGP DNA:polymorphisms:exon: RGD PMID:19477015 RGD:12910933 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MIR155 microRNA 155 ISO miRNA:increased expression:Peyer's patch RGD PMID:30206757 RGD:21409753 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR21 microRNA 21 ISO RGD PMID:30309483 RGD:41410822 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:22079846 RGD:401794136 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO RGD PMID:16610051 RGD:7777112 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO RGD PMID:28382390 RGD:13440093 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 disease_progression ISO mRNA:decreased expression:liver (rat) RGD PMID:23331901 RGD:15042883 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PARG poly(ADP-ribose) glycohydrolase treatment ISO RGD PMID:15791006 RGD:13514040 NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A IEP mRNA:increased expression:jejunum (human) RGD PMID:20965186 RGD:9999150 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa treatment IDA RGD PMID:15187522 RGD:11250409 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit treatment ISO RGD PMID:22079846 RGD:401794136 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SERPINC1 serpin family C member 1 treatment ISO RGD PMID:21046505 RGD:11035258 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SERPINE1 serpin family E member 1 ISO protein:increased activity:plasma (rat) RGD PMID:12717359 RGD:11081012 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 treatment ISO RGD PMID:27538408 RGD:151347179 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:22079846 RGD:401794136 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TRAF6 TNF receptor associated factor 6 ISO RGD PMID:27538408 RGD:151347179 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 ameliorates ISO associated with mesenteric vascular occlusion; RGD PMID:18091551 RGD:127284848 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682 		JBrowse link
G VWF von Willebrand factor ISO protein:increased expression:plasma: RGD PMID:10365842 RGD:11080742 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:23010742 RGD:13209016 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 35756
    Pathological Conditions, Signs and Symptoms 21495
      Pathologic Processes 13190
        ischemia 1557
          Intestinal Ischemia 47
            Intestinal Reperfusion Injury 43
Path 2
Term Annotations click to browse term
  disease 35756
    disease of anatomical entity 0
      cardiovascular system disease 6078
        vascular disease 3863
          ischemia 1557
            Intestinal Ischemia 47
              Intestinal Reperfusion Injury 43
paths to the root