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Gene: CLDN3 (claudin 3) Homo sapiens
Symbol: CLDN3
Name: claudin 3
Description: Predicted to have transmembrane signaling receptor activity. Involved in several processes, including positive regulation of macromolecule metabolic process; protein complex oligomerization; and regulation of wound healing. Localizes to the bicellular tight junction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C7orf1; claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-R2; CPE-receptor 2; CPETR2; HRVP1; RVP1; ventral prostate.1 protein homolog; ventral prostate.1-like protein
Mus musculus (house mouse) : Cldn3 (claudin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cldn3 (claudin 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN3 (claudin 3)
Canis lupus familiaris (dog) : CLDN3 (claudin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn3 (claudin 3)
Sus scrofa (pig) : CLDN3 (claudin 3)
Chlorocebus sabaeus (green monkey) : CLDN3 (claudin 3)
Heterocephalus glaber (naked mole-rat) : Cldn3 (claudin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl773,768,997 - 73,770,270 (-)Ensembl
GRCh38773,768,997 - 73,770,270 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,183,327 - 73,184,600 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,821,263 - 72,822,512 (-)NCBINCBI36hg18NCBI36
Build 34772,627,978 - 72,629,227NCBI
Celera768,661,514 - 68,662,787 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,065,982 - 69,067,255 (-)NCBIHuRef
CHM1_1773,329,029 - 73,330,302 (-)NCBICHM1_1
CRA_TCAGchr7v2772,516,399 - 72,517,672 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CLDN3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68632
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.