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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:monoatomic radon
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Accession:CHEBI:49999 term browser browse the term


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radon(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 ISO Radon results in increased expression of ACTA2 mRNA; Radon results in increased expression of ACTA2 protein
MK 2206 inhibits the reaction [Radon results in increased expression of ACTA2 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of ACTA2 protein]		 CTD PMID:32949624 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ar androgen receptor increases mutagenesis ISO Radon results in increased mutagenesis of AR exon CTD PMID:30008631 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 ISO Radon results in increased cleavage of CASP3 protein
Melatonin inhibits the reaction [Radon results in increased cleavage of CASP3 protein]		 CTD PMID:33107683 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression		 ISO MK 2206 inhibits the reaction [Radon results in decreased expression of CDH1 protein]; ridaforolimus inhibits the reaction [Radon results in decreased expression of CDH1 protein]
Radon results in decreased expression of CDH1 mRNA; Radon results in decreased expression of CDH1 protein		 CTD PMID:32949624 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
increases expression		 ISO MK 2206 inhibits the reaction [Radon results in increased expression of CDH2 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of CDH2 protein] CTD PMID:32949624 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases methylation ISO Radon results in increased methylation of CDKN2A promoter CTD PMID:16902270 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 increases mutagenesis ISO Radon results in increased mutagenesis of CHD4 exon CTD PMID:30008631 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Radon results in increased expression of CTNNB1 protein CTD PMID:32949624 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 ISO Radon results in increased expression of FN1 mRNA; Radon results in increased expression of FN1 protein
MK 2206 inhibits the reaction [Radon results in increased expression of FN1 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of FN1 protein]		 CTD PMID:32949624 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO Radon results in decreased expression of GSK3B protein CTD PMID:32949624 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases response to substance ISO GSTM1 gene mutant form results in increased susceptibility to Radon CTD PMID:24852519 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases response to substance ISO GSTT1 gene mutant form results in increased susceptibility to Radon CTD PMID:24852519 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Radon results in increased expression of HIF1A protein CTD PMID:32198912 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Radon results in increased expression of HK2 protein CTD PMID:32198912 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Il6 interleukin 6 affects response to substance ISO IL6 promoter SNP affects the susceptibility to Radon CTD PMID:26372664 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression		 ISO Melatonin inhibits the reaction [Radon results in increased expression of MAP1LC3B protein] CTD PMID:33107683 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation ISO Radon results in increased methylation of MGMT promoter CTD PMID:16902270 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mir1249 microRNA 1249 decreases expression ISO Radon results in decreased expression of MIR1249 mRNA CTD PMID:23294299 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712 		JBrowse link
G Mir18a microRNA 18a affects expression ISO Radon affects the expression of MIR18A mRNA CTD PMID:23294299 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir190 microRNA 190 increases expression ISO Radon results in increased expression of MIR190A mRNA CTD PMID:23294299 NCBI chr 8:67,850,987...67,851,071
Ensembl chr 8:67,850,987...67,851,071 		JBrowse link
G Mir208a microRNA 208a decreases expression ISO Radon results in decreased expression of MIR208A mRNA CTD PMID:23294299 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir375 microRNA 375 affects expression ISO Radon affects the expression of MIR375 mRNA CTD PMID:23294299 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir489 microRNA 489 decreases expression ISO Radon results in decreased expression of MIR489 mRNA CTD PMID:23294299 NCBI chr 4:31,693,355...31,693,460
Ensembl chr 4:31,693,355...31,693,460 		JBrowse link
G Mir494 microRNA 494 affects expression ISO Radon affects the expression of MIR494 mRNA CTD PMID:23294299 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir665 microRNA 665 affects expression ISO Radon affects the expression of MIR665 mRNA CTD PMID:23294299 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir711 microRNA 711 affects expression ISO Radon affects the expression of MIR711 mRNA CTD PMID:23294299 NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042 		JBrowse link
G Mir874 microRNA 874 decreases expression ISO Radon results in decreased expression of MIR874 mRNA CTD PMID:23294299 NCBI chr17:6,620,649...6,620,724
Ensembl chr17:6,620,649...6,620,724 		JBrowse link
G Mir98 microRNA 98 increases expression ISO Radon results in increased expression of MIR98 mRNA CTD PMID:23294299 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression ISO Radon results in increased expression of MIRLET7C mRNA CTD PMID:23294299 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO Radon results in increased expression of MMP2 protein CTD PMID:32949624 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression
multiple interactions		 ISO Radon results in increased expression of MTOR protein modified form
MK 2206 inhibits the reaction [Radon results in increased expression of MTOR protein modified form]; ridaforolimus inhibits the reaction [Radon results in increased expression of MTOR protein modified form]		 CTD PMID:32949624 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO Radon results in increased expression of NFE2L2 protein CTD PMID:33107683 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Radon results in increased expression of NQO1 protein CTD PMID:33107683 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO Melatonin inhibits the reaction [Radon results in decreased expression of PTGS2 mRNA] CTD PMID:33107683 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A decreases expression ISO Radon results in decreased expression of SDHA protein CTD PMID:32198912 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression		 ISO MK 2206 inhibits the reaction [Radon results in increased expression of SNAI1 protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of SNAI1 protein] CTD PMID:32949624 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions		 ISO Radon results in increased expression of SQSTM1 protein
Melatonin inhibits the reaction [Radon results in increased expression of SQSTM1 protein]		 CTD PMID:33107683 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Radon results in increased expression of TIMP2 protein CTD PMID:32949624 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tsc2 TSC complex subunit 2 increases mutagenesis ISO Radon results in increased mutagenesis of TSC2 exon CTD PMID:30008631 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Vim vimentin increases expression
multiple interactions		 ISO Radon results in increased expression of VIM mRNA; Radon results in increased expression of VIM protein
MK 2206 inhibits the reaction [Radon results in increased expression of VIM protein]; ridaforolimus inhibits the reaction [Radon results in increased expression of VIM protein]		 CTD PMID:32949624 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        elemental molecular entity 17178
          monoatomic entity 16389
            monoatomic radon 40
              radon(.1+) 0
              radon(0) 40
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