nuclear speck - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:	nuclear speck	go back to main search page
Accession:	GO:0016607	browse the term
Definition:	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
Synonyms:	exact_synonym:	nuclear speckle; nuclear speckles; splicing speckle
	narrow_synonym:	speckle domain
	related_synonym:	speckle focus

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nuclear speck
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Aff2	AF4/FMR2 family, member 2			ISO	X	155,617,378	155,970,597	RGD:1624291	RGD
G	Aff2	AF4/FMR2 family, member 2			ISO	X	155,617,378	155,970,597	RGD:1624291	RGD
G	Akap17a	A kinase (PRKA) anchor protein 17A			IEA	12	16,818,052	16,822,097	RGD:1600115	ENSEMBL
G	Alkbh5	alkB, alkylation repair homolog 5 (E. coli)			ISS	10	46,811,205	46,832,649	RGD:1600115	UniProtKB
G	Alkbh5	alkB, alkylation repair homolog 5 (E. coli)			ISO	10	46,811,205	46,832,649	RGD:1624291	RGD
G	Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)			IEA	1	163,282,918	163,299,333	RGD:1600115	UniProtKB
G	Apex1	APEX nuclease (multifunctional DNA repair enzyme) 1			ISO	15	26,904,124	26,906,224	RGD:1624291	RGD
G	Apex1	APEX nuclease (multifunctional DNA repair enzyme) 1			ISS	15	26,904,124	26,906,224	RGD:1600115	UniProtKB
G	Atpaf2	ATP synthase mitochondrial F1 complex assembly factor 2			IEA	10	46,668,951	46,684,301	RGD:1600115	ENSEMBL
G	Atpaf2	ATP synthase mitochondrial F1 complex assembly factor 2			ISO	10	46,668,951	46,684,301	RGD:1624291	RGD
G	Atxn2l	ataxin 2-like			ISO	1	185,637,263	185,647,581	RGD:1624291	RGD
G	Basp1	brain abundant, membrane attached signal protein 1			ISO	2	76,877,616	76,927,721	RGD:1624291	RGD
G	Basp1	brain abundant, membrane attached signal protein 1			ISS	2	76,877,616	76,927,721	RGD:1600115	UniProtKB
G	Casc3	cancer susceptibility candidate 3			IEA	10	87,581,850	87,602,528	RGD:1600115	UniProtKB
G	Cby1	chibby homolog 1 (Drosophila)			IEA	7	117,903,217	117,908,964	RGD:1600115	UniProtKB
G	Ccnl1	cyclin L1			IDA	2	155,757,335	155,769,633	RGD:632453	RGD
G	Ccnl2	cyclin L2			IEA	5	172,666,512	172,673,024	RGD:1600115	UniProtKB
G	Cd2bp2	Cd2 (cytoplasmic tail) binding protein 2		colocalizes_with	ISO	1	186,451,415	186,455,407	RGD:1624291	RGD
G	Cd2bp2	Cd2 (cytoplasmic tail) binding protein 2			IEA	1	186,451,415	186,455,407	RGD:1600115	ENSEMBL
G	Cdc5l	cell division cycle 5-like			IDA	9	11,165,631	11,204,135	RGD:619664	RGD
G	Cdc5l	cell division cycle 5-like			ISO	9	11,165,631	11,204,135	RGD:1624291	RGD
G	Cdk12	cyclin-dependent kinase 12			ISO	10	86,972,428	87,027,794	RGD:1624291	RGD
G	Cdk12	cyclin-dependent kinase 12			IDA	10	86,972,428	87,027,794		UniProtKB
G	Cdk13	cyclin-dependent kinase 13			ISO	17	55,146,130	55,235,545	RGD:1624291	RGD
G	Cir1	corepressor interacting with RBPJ, 1			IEA	3	55,789,080	55,818,634	RGD:1600115	UniProtKB
G	Csnk1a1	casein kinase 1, alpha 1			ISO	18	57,541,673	57,564,560	RGD:1624291	RGD
G	Csnk1a1	casein kinase 1, alpha 1			IEA	18	57,541,673	57,564,560	RGD:1600115	ENSEMBL
G	Csnk1a1	casein kinase 1, alpha 1			ISS	18	57,541,673	57,564,560	RGD:1600115	UniProtKB
G	Cxxc1	CXXC finger protein 1			IEA	18	71,006,887	71,011,947	RGD:1600115	ENSEMBL
G	Cxxc1	CXXC finger protein 1			ISO	18	71,006,887	71,011,947	RGD:1624291	RGD
G	Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B			IEA	20	3,611,128	3,623,578	RGD:1600115	UniProtKB
G	Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46			IEA	17	14,985,633	15,029,607	RGD:1600115	UniProtKB
G	Dgkq	diacylglycerol kinase, theta			ISO	14	1,600,280	1,614,154	RGD:1624291	RGD
G	Dgkq	diacylglycerol kinase, theta			IEA	14	1,600,280	1,614,154	RGD:1600115	ENSEMBL
G	Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A			IDA	11	34,879,733	34,970,998		UniProtKB
G	Eaf2	ELL associated factor 2			IEA	11	65,763,410	65,809,967	RGD:1600115	UniProtKB
G	Eftud2	elongation factor Tu GTP binding domain containing 2			ISO	10	92,012,161	92,053,043	RGD:1624291	RGD
G	Eftud2	elongation factor Tu GTP binding domain containing 2			IEA	10	92,012,161	92,053,043	RGD:1600115	ENSEMBL
G	Eif4a3	eukaryotic translation initiation factor 4A, isoform 3			IEA				RGD:1600115	UniProtKB
G	Ell	elongation factor RNA polymerase II			ISO	16	19,349,939	19,397,253	RGD:1624291	RGD
G	Ep400	E1A binding protein p400			ISO	12	46,036,453	46,143,426	RGD:1624291	RGD
G	Ep400	E1A binding protein p400			IEA	12	46,036,453	46,143,426	RGD:1600115	ENSEMBL
G	Fastk	Fas-activated serine/threonine kinase			ISO	4	6,096,675	6,100,690	RGD:1624291	RGD
G	Fyttd1	forty-two-three domain containing 1			ISO	11	69,700,526	69,720,622	RGD:1624291	RGD
G	Fyttd1	forty-two-three domain containing 1			ISS	11	69,700,526	69,720,622	RGD:1600115	UniProtKB
G	Gli2	GLI family zinc finger 2			ISO	13	31,551,089	31,607,264	RGD:1624291	RGD
G	Gli3	GLI family zinc finger 3			ISO	17	57,594,102	57,867,710	RGD:1624291	RGD
G	Gli3	GLI family zinc finger 3			IDA	17	57,594,102	57,867,710	RGD:2290270	MGI
G	Glis2	GLIS family zinc finger 2			ISO	10	11,080,702	11,100,905	RGD:1624291	RGD
G	Glis2	GLIS family zinc finger 2			IEA	10	11,080,702	11,100,905	RGD:1600115	ENSEMBL
G	Hipk1	homeodomain interacting protein kinase 1			ISO	2	198,963,076	199,014,710	RGD:1624291	RGD
G	Hspa1a	heat shock protein 1A			ISO	20	3,945,716	3,959,552	RGD:1624291	RGD
G	Hspa1a	heat shock protein 1A			ISS	20	3,945,716	3,959,552	RGD:1600115	UniProtKB
G	Hspa1b	heat shock protein 1B			ISO	20	3,955,274	3,957,748	RGD:1624291	RGD
G	Hspa1b	heat shock protein 1B			ISS	20	3,955,274	3,957,748	RGD:1600115	UniProtKB
G	LOC687575	similar to Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit)			IEA				RGD:1600115	ENSEMBL
G	Magoh	mago-nashi homolog, proliferation-associated (Drosophila)			IEA	5	128,982,276	128,989,724	RGD:1600115	UniProtKB
G	Mbd1	methyl-CpG binding domain protein 1			ISO	18	71,068,257	71,082,734	RGD:1624291	RGD
G	Mbd1	methyl-CpG binding domain protein 1			IEA	18	71,068,257	71,082,734	RGD:1600115	ENSEMBL
G	Mecom	MDS1 and EVI1 complex locus			IEA	2	114,814,409	114,882,676	RGD:1600115	ENSEMBL
G	Mef2c	myocyte enhancer factor 2C			ISO	2	12,331,078	12,346,520	RGD:1624291	RGD
G	Mef2c	myocyte enhancer factor 2C			ISS	2	12,331,078	12,346,520	RGD:1600115	UniProtKB
G	Meox2	mesenchyme homeobox 2			IEA	6	55,895,760	55,957,066	RGD:1600115	UniProtKB
G	Nek6	NIMA-related kinase 6			IEA	3	18,348,698	18,381,895	RGD:1600115	UniProtKB
G	Noc3l	nucleolar complex associated 3 homolog (S. cerevisiae)			ISO	1	243,108,787	243,137,316	RGD:1624291	RGD
G	Noc3l	nucleolar complex associated 3 homolog (S. cerevisiae)			IEA	1	243,108,787	243,137,316	RGD:1600115	ENSEMBL
G	Nono	non-POU domain containing, octamer-binding			IEA	X	89,502,318	89,520,178	RGD:1600115	UniProtKB
G	Npm1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)			ISO	10	18,051,990	18,062,714	RGD:1624291	RGD
G	Nsrp1	nuclear speckle splicing regulatory protein 1			ISO	10	67,078,478	67,112,148	RGD:1624291	RGD
G	Nsrp1	nuclear speckle splicing regulatory protein 1			ISS	10	67,078,478	67,112,148	RGD:1600115	UniProtKB
G	Nsrp1	nuclear speckle splicing regulatory protein 1			ISO	10	67,078,478	67,112,148	RGD:1624291	RGD
G	Nxf1	nuclear RNA export factor 1			IEA	1	211,428,605	211,441,798	RGD:1600115	UniProtKB
G	Ogg1	8-oxoguanine DNA glycosylase			ISO	4	149,209,745	149,219,081	RGD:1624291	RGD
G	Ogg1	8-oxoguanine DNA glycosylase			ISS	4	149,209,745	149,219,081	RGD:1600115	UniProtKB
G	Patl1	protein associated with topoisomerase II homolog 1 (yeast)			IEA	1	214,755,170	214,787,272	RGD:1600115	UniProtKB
G	Phf5a	PHD finger protein 5A			ISO	7	120,216,581	120,223,146	RGD:1624291	RGD
G	Phf5a	PHD finger protein 5A			ISS	7	120,216,581	120,223,146	RGD:1600115	UniProtKB
G	Pias2	protein inhibitor of activated STAT, 2			IEA	18	74,078,683	74,123,668	RGD:1600115	UniProtKB
G	Pias3	protein inhibitor of activated STAT, 3			IEA	2	191,499,057	191,507,221	RGD:1600115	UniProtKB
G	Pip5k1a	phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha			IEA	2	189,962,527	190,005,684	RGD:1600115	ENSEMBL
G	Pip5k1a	phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha			ISO	2	189,962,527	190,005,684	RGD:1624291	RGD
G	Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)			ISO	3	122,797,718	123,523,675	RGD:1624291	RGD
G	Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)			ISO	3	122,797,718	123,523,675	RGD:1624291	RGD
G	Plcb1	phospholipase C, beta 1 (phosphoinositide-specific)			ISS	3	122,797,718	123,523,675	RGD:1600115	BHF-UCL
G	Plrg1	pleiotropic regulator 1			IEA	2	174,780,415	174,796,746	RGD:1600115	UniProtKB
G	Pnn	pinin, desmosome associated protein			ISO	6	79,759,026	79,767,339	RGD:1624291	RGD
G	Pnn	pinin, desmosome associated protein			IEA	6	79,759,026	79,767,339	RGD:1600115	ENSEMBL
G	Poldip3	polymerase (DNA-directed), delta interacting protein 3			IEA	7	121,155,485	121,184,392	RGD:1600115	ENSEMBL
G	Poldip3	polymerase (DNA-directed), delta interacting protein 3			ISO	7	121,155,485	121,184,392	RGD:1624291	RGD
G	Ppig	peptidylprolyl isomerase G			IEA	3	51,866,989	51,895,893	RGD:1600115	UniProtKB
G	Ppih	peptidylprolyl isomerase H (cyclophilin H)			ISO	5	139,959,365	139,969,320	RGD:1624291	RGD
G	Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isozyme			IEA	12	35,580,169	35,598,249	RGD:1600115	UniProtKB
G	Ppp1r8	protein phosphatase 1, regulatory subunit 8			ISO	5	152,305,936	152,323,075	RGD:1624291	RGD
G	Ppp1r8	protein phosphatase 1, regulatory subunit 8			IEA	5	152,305,936	152,323,075	RGD:1600115	ENSEMBL
G	Prpf18	PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)			IEA	17	84,741,279	84,773,449	RGD:1600115	UniProtKB
G	Prpf19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)			ISO	1	213,390,564	213,401,943	RGD:1624291	RGD
G	Prpf19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)			IEA	1	213,390,564	213,401,943	RGD:1600115	ENSEMBL
G	Prpf31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)			IEA	1	63,888,815	63,900,490	RGD:1600115	ENSEMBL
G	Prpf31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)			ISO	1	63,888,815	63,900,490	RGD:1624291	RGD
G	Prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)			IEA	3	170,740,406	170,804,674	RGD:1600115	UniProtKB
G	Pspc1	paraspeckle component 1			IEA	15	35,718,357	35,779,139	RGD:1600115	UniProtKB
G	Rbm4	RNA binding motif protein 4			ISO	1	207,394,470	207,403,393	RGD:1624291	RGD
G	Rbm4	RNA binding motif protein 4			ISO	1	207,394,470	207,403,393	RGD:1624291	RGD
G	Rbm8a	RNA binding motif protein 8A			IEA	2	191,429,805	191,432,261	RGD:1600115	UniProtKB
G	Ring1	ring finger protein 1			IEA	20	4,968,251	4,972,149	RGD:1600115	UniProtKB
G	Rnf34	ring finger protein 34, E3 ubiquitin protein ligase			IEA	12	34,805,137	34,826,016	RGD:1600115	UniProtKB
G	Rnps1	ribonucleic acid binding protein S1			IEA	10	13,670,753	13,681,591	RGD:1600115	UniProtKB
G	Rsrc1	arginine/serine-rich coiled-coil 1			ISO	2	156,889,768	157,213,294	RGD:1624291	RGD
G	Rsrc1	arginine/serine-rich coiled-coil 1			ISS	2	156,889,768	157,213,294	RGD:1600115	UniProtKB
G	Slu7	SLU7 splicing factor homolog (S. cerevisiae)			ISS	10	28,536,630	28,551,427	RGD:1304333	HGNC
G	Smndc1	survival motor neuron domain containing 1			IEA	1	259,596,813	259,607,340	RGD:1600115	UniProtKB
G	Spop	speckle-type POZ protein			ISO	10	84,099,990	84,185,130	RGD:1624291	RGD
G	Sprtn	SprT-like N-terminal domain			IEA	19	55,069,130	55,073,670	RGD:1600115	ENSEMBL
G	Sprtn	SprT-like N-terminal domain			ISO	19	55,069,130	55,073,670	RGD:1624291	RGD
G	Srp54	signal recognition particle 54A			IEA	6	75,446,838	75,494,001	RGD:1600115	UniProtKB
G	Srsf1	serine/arginine-rich splicing factor 1			ISO	10	76,339,824	76,344,552	RGD:1624291	RGD
G	Srsf1	serine/arginine-rich splicing factor 1			ISO	10	76,339,824	76,344,552	RGD:1624291	RGD
G	Srsf1	serine/arginine-rich splicing factor 1			IEA	10	76,339,824	76,344,552	RGD:1600115	ENSEMBL
G	Srsf1	serine/arginine-rich splicing factor 1			ISO	10	76,339,824	76,344,552	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			ISO	10	106,954,365	106,956,807	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			ISO	10	106,954,365	106,956,807	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			ISO	10	106,954,365	106,956,807	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			ISO	10	106,954,365	106,956,807	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			ISO	10	106,954,365	106,956,807	RGD:1624291	RGD
G	Srsf2	serine/arginine-rich splicing factor 2			IEA	10	106,954,365	106,956,807	RGD:1600115	ENSEMBL
G	Srsf2	serine/arginine-rich splicing factor 2			IEA	10	106,954,365	106,956,807	RGD:1600115	ENSEMBL
G	Srsf3	serine/arginine-rich splicing factor 3			ISO	20	7,316,649	7,326,580	RGD:1624291	RGD
G	Srsf5	serine/arginine-rich splicing factor 5			ISS	6	104,728,286	104,732,982	RGD:1600115	UniProtKB
G	Srsf5	serine/arginine-rich splicing factor 5			ISO	6	104,728,286	104,732,982	RGD:1624291	RGD
G	Sry	sex determining region Y			IEA				RGD:1600115	UniProtKB
G	Sumo1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)			IEA	9	58,212,538	58,242,760	RGD:1600115	UniProtKB
G	Tardbp	TAR DNA binding protein			IDA	5	165,698,665	165,709,531	RGD:5687141	RGD
G	Tfip11	tuftelin interacting protein 11			ISO	19	14,307,576	14,319,808	RGD:1624291	RGD
G	Tfip11	tuftelin interacting protein 11			IEA	19	14,307,576	14,319,808	RGD:1600115	ENSEMBL
G	Thap7	THAP domain containing 7			IEA	11	85,474,475	85,477,516	RGD:1600115	ENSEMBL
G	Thap7	THAP domain containing 7			ISO	11	85,474,475	85,477,516	RGD:1624291	RGD
G	Thoc1	THO complex 1			IEA	18	1,256,731	1,290,988	RGD:1600115	UniProtKB
G	Topors	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase			IEA	5	57,663,121	57,676,619	RGD:1600115	ENSEMBL
G	Topors	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase			ISO	5	57,663,121	57,676,619	RGD:1624291	RGD
G	Trim69	tripartite motif-containing 69			ISO	3	108,943,306	108,963,931	RGD:1624291	RGD
G	Trim69	tripartite motif-containing 69			ISS	3	108,943,306	108,963,931	RGD:1600115	UniProtKB
G	Tut1	terminal uridylyl transferase 1, U6 snRNA-specific			ISO	1	211,629,025	211,640,008	RGD:1624291	RGD
G	Tut1	terminal uridylyl transferase 1, U6 snRNA-specific			ISO	1	211,629,025	211,640,008	RGD:1624291	RGD
G	Tut1	terminal uridylyl transferase 1, U6 snRNA-specific			ISS	1	211,629,025	211,640,008	RGD:1600115	UniProtKB
G	U2af1l4	U2 small nuclear RNA auxiliary factor 1-like 4			IEA	1	85,608,372	85,610,419	RGD:1600115	UniProtKB
G	Wbp11	WW domain binding protein 11			ISO	4	173,823,936	173,837,308	RGD:1624291	RGD
G	Wbp4	WW domain binding protein 4			ISO	15	61,517,401	61,543,453	RGD:1624291	RGD
G	Wbp4	WW domain binding protein 4			ISS	15	61,517,401	61,543,453	RGD:1600115	UniProtKB
G	Wt1	Wilms tumor 1			ISO	3	90,529,704	90,577,280	RGD:1624291	RGD
G	Wt1	Wilms tumor 1			ISO	3	90,529,704	90,577,280	RGD:1624291	RGD
G	Wt1	Wilms tumor 1			ISO	3	90,529,704	90,577,280	RGD:1624291	RGD
G	Wt1	Wilms tumor 1			ISS	3	90,529,704	90,577,280	RGD:1600115	UniProtKB
G	Wt1	Wilms tumor 1			ISS	3	90,529,704	90,577,280	RGD:1600115	UniProtKB
G	Ylpm1	YLP motif containing 1			IEA	6	109,041,410	109,117,751	RGD:1600115	UniProtKB
G	Zbtb16	zinc finger and BTB domain containing 16			ISO	8	51,931,530	52,094,813	RGD:1624291	RGD
G	Zbtb16	zinc finger and BTB domain containing 16			ISS	8	51,931,530	52,094,813	RGD:1600115	UniProtKB
G	Zc3h14	zinc finger CCCH type containing 14			IEA	6	122,919,317	122,956,935	RGD:1600115	UniProtKB
G	Zcchc12	zinc finger, CCHC domain containing 12			ISO	X	8,729,463	8,732,648	RGD:1624291	RGD
G	Zcchc12	zinc finger, CCHC domain containing 12			IEA	X	8,729,463	8,732,648	RGD:1600115	ENSEMBL
G	Zfp830	zinc finger protein 830			ISO	10	70,983,767	70,985,231	RGD:1624291	RGD

Term paths to the root

Path 1
Term	Annotations
cellular_component	76568
organelle part	15012
intracellular organelle part	14503
nuclear part	6384
nucleoplasm part	1781
nuclear body	431
nuclear speck	160
omega speckle	0
Path 2
Term	Annotations
cellular_component	76568
cell	60552
cell part	60544
intracellular	47229
intracellular part	46462
intracellular organelle	34824
intracellular membrane-bounded organelle	28637
nucleus	15146
nuclear part	6384
nuclear lumen	4823
nucleoplasm	2054
nucleoplasm part	1781
nuclear body	431
nuclear speck	160
omega speckle	0