ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear speck
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Accession:GO:0016607 term browser browse the term
Definition:A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
Synonyms:exact_synonym: nuclear speckle;   nuclear speckles;   splicing speckle
 narrow_synonym: speckle domain
 related_synonym: speckle focus


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nuclear speck term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acin1 apoptotic chromatin condensation inducer 1 JBrowse link 15 33,288,369 33,333,256 RGD:1600115
RGD:1624291
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:10755332
G Aff2 AF4/FMR2 family, member 2 JBrowse link X 153,539,951 154,051,022 RGD:1600115
RGD:1624291
G Aggf1 angiogenic factor with G patch and FHA domains 1 JBrowse link 2 25,068,804 25,095,429 RGD:1600115
G Akap17a A-kinase anchoring protein 17A JBrowse link 12 18,527,116 18,531,780 RGD:1600115
RGD:1624291
G Akap8l A-kinase anchoring protein 8 like JBrowse link 7 14,340,168 14,369,835 RGD:1624291
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1600115
RGD:1624291
G Apbb1 amyloid beta precursor protein binding family B member 1 JBrowse link 1 170,387,625 170,411,263 RGD:1600115
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:1600115
RGD:1624291
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 JBrowse link 12 37,904,376 37,906,521 RGD:1600115
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 JBrowse link 10 46,768,539 46,783,889 RGD:1600115
RGD:1624291
G Atxn2l ataxin 2-like JBrowse link 1 197,908,087 197,920,400 RGD:1600115
RGD:1624291
G Basp1 brain abundant, membrane attached signal protein 1 JBrowse link 2 77,586,424 77,632,626 RGD:1600115
RGD:1624291
G Bclaf1 BCL2-associated transcription factor 1 JBrowse link 1 15,799,753 15,828,838 RGD:1600115
RGD:1624291
G Casc3 cancer susceptibility candidate 3 JBrowse link 10 86,724,534 86,744,485 RGD:1600115
G Cby1 chibby family member 1, beta catenin antagonist JBrowse link 7 120,891,930 120,898,318 RGD:1600115
G Ccnl1 cyclin L1 JBrowse link 2 157,747,295 157,759,838 RGD:632453
G Ccnl2 cyclin L2 JBrowse link 5 173,256,301 173,268,279 RGD:1600115
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 JBrowse link 1 198,635,445 198,641,195 RGD:1600115
RGD:1624291
G Cdc5l cell division cycle 5-like JBrowse link 9 17,949,764 17,988,514 RGD:619664
RGD:1600115
RGD:1624291
G Cdk12 cyclin-dependent kinase 12 JBrowse link 10 86,157,186 86,210,657 RGD:1624291
RGD:8553775
G Cdk13 cyclin-dependent kinase 13 JBrowse link 17 49,833,194 49,922,932 RGD:1600115
RGD:1624291
G Chtop chromatin target of PRMT1 JBrowse link 2 189,887,850 189,900,079 RGD:1600115
RGD:1624291
G Cir1 corepressor interacting with RBPJ, 1 JBrowse link 3 59,994,547 60,023,843 RGD:1600115
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:1600115
RGD:1624291
RGD:10059666
G Cwc22 CWC22 spliceosome associated protein homolog JBrowse link 3 64,731,145 64,780,127 RGD:1624291
G Cxxc1 CXXC finger protein 1 JBrowse link 18 70,192,520 70,197,871 RGD:1600115
RGD:1624291
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Ddx39b DEAD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:1600115
G Ddx46 DEAD-box helicase 46 JBrowse link 17 9,475,275 9,519,545 RGD:1600115
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1600115
RGD:1624291
G Dusp11 dual specificity phosphatase 11 JBrowse link 4 117,617,640 117,631,674 RGD:1600115
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A JBrowse link 11 34,858,339 34,958,733 RGD:8554210
RGD:8554265
G Eaf2 ELL associated factor 2 JBrowse link 11 66,878,658 66,923,092 RGD:1600115
G Eftud2 elongation factor Tu GTP binding domain containing 2 JBrowse link 10 90,932,071 90,983,971 RGD:1600115
RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 JBrowse link 10 108,415,201 108,425,195 RGD:1600115
G Ell elongation factor for RNA polymerase II JBrowse link 16 20,594,129 20,641,441 RGD:1600115
RGD:1624291
G Ep400 E1A binding protein p400 JBrowse link 12 51,948,650 52,055,274 RGD:1600115
RGD:1624291
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:1600115
RGD:1624291
RGD:2290270
G Fam206a family with sequence similarity 206, member A JBrowse link 5 73,552,952 73,560,240 RGD:1600115
RGD:1624291
G Fastk Fas-activated serine/threonine kinase JBrowse link 4 7,260,521 7,264,590 RGD:1624291
G Fto fat mass and obesity associated JBrowse link 19 16,774,549 17,115,098 RGD:1600115
RGD:1624291
G Fyttd1 forty-two-three domain containing 1 JBrowse link 11 71,113,931 71,136,694 RGD:1600115
RGD:1624291
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1600115
RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1600115
RGD:1624291
RGD:2290270
G Glis2 GLIS family zinc finger 2 JBrowse link 10 11,154,459 11,177,063 RGD:1600115
RGD:1624291
G Hif1a hypoxia inducible factor 1 alpha subunit JBrowse link 6 96,810,868 96,856,303 RGD:1600115
RGD:1624291
G Hif3a hypoxia inducible factor 3, alpha subunit JBrowse link 1 78,976,318 78,997,869 RGD:1600115
G Hipk1 homeodomain interacting protein kinase 1 JBrowse link 2 206,224,015 206,274,910 RGD:1600115
RGD:1624291
G LOC100910163 uncharacterized LOC100910163 JBrowse link 16 72,401,526 72,403,180 RGD:1624291
G LOC103690006 RNA/RNP complex-1-interacting phosphatase JBrowse link 4 117,797,735 117,814,732 RGD:1600115
G Magoh mago homolog, exon junction complex core component JBrowse link 5 127,480,465 127,487,617 RGD:1600115
G Maml2 mastermind-like transcriptional coactivator 2 JBrowse link 8 11,929,238 12,253,991 RGD:1600115
G Mbd1 methyl-CpG binding domain protein 1 JBrowse link 18 70,248,568 70,263,190 RGD:1624291
G Mecom MDS1 and EVI1 complex locus JBrowse link 2 117,396,084 117,993,604 RGD:1600115
RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Meox2 mesenchyme homeobox 2 JBrowse link 6 56,625,768 56,689,195 RGD:1600115
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1600115
RGD:1624291
G Mtfr2 mitochondrial fission regulator 2 JBrowse link 1 15,834,779 15,850,424 RGD:1600115
G Nek6 NIMA-related kinase 6 JBrowse link 3 22,811,927 22,888,598 RGD:1600115
G Noc3l NOC3-like DNA replication regulator JBrowse link 1 257,469,538 257,498,844 RGD:1600115
RGD:1624291
G Nono non-POU domain containing, octamer-binding JBrowse link X 71,324,365 71,342,225 RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1600115
RGD:1624291
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:1600115
RGD:1624291
G Nsrp1 nuclear speckle splicing regulatory protein 1 JBrowse link 10 63,098,115 63,131,779 RGD:1600115
RGD:1624291
G Nxf1 nuclear RNA export factor 1 JBrowse link 1 224,957,535 224,970,728 RGD:1600115
RGD:1624291
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:1600115
RGD:1624291
G Patl1 PAT1 homolog 1, processing body mRNA decay factor JBrowse link 1 228,337,756 228,369,719 RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1600115
RGD:1624291
G Phf5a PHD finger protein 5A JBrowse link 7 123,095,286 123,101,851 RGD:1600115
RGD:1624291
G Pias2 protein inhibitor of activated STAT, 2 JBrowse link 18 73,479,863 73,524,956 RGD:1600115
G Pias3 protein inhibitor of activated STAT, 3 JBrowse link 2 198,821,377 198,831,533 RGD:1600115
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha JBrowse link 2 196,227,669 196,270,949 RGD:1600115
RGD:1624291
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1600115
RGD:1624291
G Plrg1 pleiotropic regulator 1 JBrowse link 2 182,040,338 182,056,669 RGD:1600115
G Pnn pinin, desmosome associated protein JBrowse link 6 80,159,364 80,167,677 RGD:1624291
G Poldip3 DNA polymerase delta interacting protein 3 JBrowse link 7 123,992,167 124,020,596 RGD:1624291
G Ppig peptidylprolyl isomerase G JBrowse link 3 55,959,756 55,990,040 RGD:1600115
G Ppih peptidylprolyl isomerase H JBrowse link 5 138,343,934 138,361,743 RGD:1600115
RGD:1624291
G Ppp1cc protein phosphatase 1 catalytic subunit gamma JBrowse link 12 39,864,302 39,882,030 RGD:1600115
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 JBrowse link 5 151,012,035 151,029,227 RGD:1600115
RGD:1624291
G Pqbp1 polyglutamine binding protein 1 JBrowse link X 15,448,570 15,453,130 RGD:1600115
RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
G Prpf18 pre-mRNA processing factor 18 JBrowse link 17 77,601,914 77,632,507 RGD:1600115
G Prpf19 pre-mRNA processing factor 19 JBrowse link 1 226,947,065 226,958,147 RGD:1600115
RGD:1624291
G Prpf31 pre-mRNA processing factor 31 JBrowse link 1 64,150,786 64,162,461 RGD:1600115
RGD:1624291
G Prpf4 pre-mRNA processing factor 4 JBrowse link 5 78,267,248 78,281,172 RGD:1600115
RGD:1624291
G Prpf6 pre-mRNA processing factor 6 JBrowse link 3 177,098,137 177,162,937 RGD:1600115
G Pspc1 paraspeckle component 1 JBrowse link 15 36,946,914 37,030,273 RGD:1600115
G Rad54l2 RAD54-like 2 (S. cerevisiae) JBrowse link 8 115,392,891 115,490,640 RGD:1624291
G Rbm11 RNA binding motif protein 11 JBrowse link 11 14,005,704 14,015,723 RGD:1600115
RGD:1624291
G Rbm15 RNA binding motif protein 15 JBrowse link 2 210,079,678 210,090,200 RGD:1600115
RGD:1624291
G Rbm25 RNA binding motif protein 25 JBrowse link 6 107,117,888 107,165,538 RGD:1624291
G Rbm4 RNA binding motif protein 4 JBrowse link 1 220,038,403 220,049,756 RGD:1600115
RGD:1624291
G Rbm8a RNA binding motif protein 8A JBrowse link 2 198,755,261 198,758,028 RGD:1600115
G RGD1559904 similar to mKIAA1429 protein JBrowse link 5 25,042,743 25,121,403 RGD:1600115
RGD:1624291
G Ring1 ring finger protein 1 JBrowse link 20 3,812,287 3,815,834 RGD:1600115
G Rnf34 ring finger protein 34 JBrowse link 12 39,164,290 39,185,209 RGD:1600115
G Rnps1 RNA binding protein S1 JBrowse link 10 13,786,339 13,796,720 RGD:1600115
G Rsrc1 arginine and serine rich coiled-coil 1 JBrowse link 2 164,126,898 164,533,652 RGD:1600115
RGD:1624291
G Sap18 Sin3-associated polypeptide 18 JBrowse link 15 38,069,320 38,073,625 RGD:1624291
G Sarnp SAP domain containing ribonucleoprotein JBrowse link 7 3,246,220 3,300,467 RGD:1600115
RGD:1624291
G Sf3a2 splicing factor 3a, subunit 2 JBrowse link 7 11,777,826 11,784,373 RGD:10053725
G Slu7 SLU7 homolog, splicing factor JBrowse link 10 29,029,556 29,044,919 RGD:1304333
RGD:1600115
RGD:1624291
G Smndc1 survival motor neuron domain containing 1 JBrowse link 1 274,096,068 274,107,138 RGD:1600115
G Son Son DNA binding protein JBrowse link 11 31,806,598 31,837,769 RGD:1600115
RGD:1624291
G Spop speckle type BTB/POZ protein JBrowse link 10 83,231,187 83,311,987 RGD:1600115
RGD:1624291
G Sprtn SprT-like N-terminal domain JBrowse link 19 57,649,901 57,657,158 RGD:1600115
RGD:1624291
G Srp54a signal recognition particle 54A JBrowse link 6 75,996,629 76,035,768 RGD:1600115
G Srrm2 serine/arginine repetitive matrix 2 JBrowse link 10 13,128,820 13,162,956 RGD:1600115
RGD:1624291
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:1600115
RGD:1624291
G Srsf10 serine and arginine rich splicing factor 10 JBrowse link 5 154,205,358 154,219,550 RGD:1624291
G Srsf2 serine and arginine rich splicing factor 2 JBrowse link 10 105,792,779 105,795,986 RGD:1624291
RGD:11038801
G Srsf3 serine and arginine rich splicing factor 3 JBrowse link 20 6,288,285 6,298,218 RGD:1624291
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:1600115
RGD:1624291
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:1600115
RGD:1624291
G Sry sex determining region Y JBrowse link Y 327,176 327,685 RGD:1600115
G Sumo1 small ubiquitin-like modifier 1 JBrowse link 9 66,453,428 66,483,614 RGD:1600115
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:5687141
G Tfip11 tuftelin interacting protein 11 JBrowse link 12 50,320,820 50,333,052 RGD:1600115
RGD:1624291
G Thap7 THAP domain containing 7 JBrowse link 11 87,399,430 87,403,381 RGD:1600115
RGD:1624291
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1600115
G Thoc6 THO complex 6 JBrowse link 10 12,989,135 12,994,495 RGD:1600115
G Thrap3 thyroid hormone receptor associated protein 3 JBrowse link 5 144,178,248 144,221,318 RGD:1600115
RGD:1624291
G Timm50 translocase of inner mitochondrial membrane 50 JBrowse link 1 85,470,810 85,480,813 RGD:1600115
RGD:1624291
G Topors TOP1 binding arginine/serine rich protein JBrowse link 5 56,554,956 56,566,503 RGD:1600115
RGD:1624291
G Trim69 tripartite motif-containing 69 JBrowse link 3 114,103,011 114,123,293 RGD:1600115
RGD:1624291
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific JBrowse link 1 225,151,462 225,162,445 RGD:1600115
RGD:1624291
G U2af1 U2 small nuclear RNA auxiliary factor 1 JBrowse link 20 10,396,652 10,407,564 RGD:1600115
RGD:1624291
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 JBrowse link 1 89,017,414 89,019,651 RGD:1600115
G U2af2 U2 small nuclear RNA auxiliary factor 2 JBrowse link 1 72,312,260 72,329,828 RGD:1600115
RGD:1624291
G Wbp11 WW domain binding protein 11 JBrowse link 4 170,772,166 170,785,613 RGD:1624291
G Wbp4 WW domain binding protein 4 JBrowse link 15 61,745,989 61,772,516 RGD:1600115
RGD:1624291
G Wt1 Wilms tumor 1 JBrowse link 3 95,133,221 95,180,574 RGD:1600115
RGD:1624291
G Wtap Wilms tumor 1 associated protein JBrowse link 1 47,942,500 47,967,633 RGD:1600115
RGD:1624291
G Ylpm1 YLP motif containing 1 JBrowse link 6 108,820,774 108,897,209 RGD:1600115
G Ythdc1 YTH domain containing 1 JBrowse link 14 22,971,834 23,002,326 RGD:1600115
RGD:1624291
G Zbtb16 zinc finger and BTB domain containing 16 JBrowse link 8 52,980,226 53,146,765 RGD:1600115
RGD:1624291
G Zc3h13 zinc finger CCCH type containing 13 JBrowse link 15 57,340,522 57,405,287 RGD:1600115
RGD:1624291
G Zc3h14 zinc finger CCCH type containing 14 JBrowse link 6 122,729,834 122,767,462 RGD:1600115
G Zcchc12 zinc finger CCHC-type containing 12 JBrowse link X 122,808,581 122,811,790 RGD:1600115
RGD:1624291
G Zfp830 zinc finger protein 830 JBrowse link 10 70,118,250 70,119,714 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 358472
    organelle part 77336
      intracellular organelle part 74372
        nuclear part 39365
          nucleoplasm part 4183
            nuclear body 1495
              nuclear speck 606
                omega speckle 0
Path 2
Term Annotations click to browse term
  cellular_component 358472
    cell 263341
      cell part 263040
        intracellular 202933
          intracellular part 199819
            intracellular organelle 138986
              intracellular membrane-bounded organelle 116431
                nucleus 66798
                  nuclear part 39365
                    nuclear lumen 32862
                      nucleoplasm 25239
                        nucleoplasm part 4183
                          nuclear body 1495
                            nuclear speck 606
                              omega speckle 0
paths to the root