ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear speck
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Accession:GO:0016607 term browser browse the term
Definition:A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
Synonyms:exact_synonym: nuclear speckle;   nuclear speckles;   splicing speckle
 narrow_synonym: speckle domain
 related_synonym: speckle focus


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nuclear speck term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Acin1 apoptotic chromatin condensation inducer 1 GBrowse link 15 37,173,164 37,218,052 RGD:1600115
RGD:1624291
G Aff2 AF4/FMR2 family, member 2 GBrowse link 1 149,265,910 149,777,658 RGD:1600115
RGD:1624291
G Akap17a A kinase (PRKA) anchor protein 17A GBrowse link 12 20,512,066 20,516,849 RGD:1600115
RGD:1624291
G Alkbh5 AlkB family member 5, RNA demethylase GBrowse link 10 46,679,920 46,700,727 RGD:1600115
RGD:1624291
G Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) GBrowse link 1 177,393,531 177,417,140 RGD:1600115
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link 15 31,682,368 31,684,508 RGD:1600115
RGD:1624291
G Arl6ip4 ADP-ribosylation factor-like 6 interacting protein 4 GBrowse link 12 39,776,739 39,778,884 RGD:1600115
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 GBrowse link 10 46,523,866 46,539,216 RGD:1600115
RGD:1624291
G Atxn2l ataxin 2-like GBrowse link 1 204,886,847 204,898,772 RGD:1600115
RGD:1624291
G Basp1 brain abundant, membrane attached signal protein 1 GBrowse link 2 97,311,340 97,358,165 RGD:1600115
G Casc3 cancer susceptibility candidate 3 GBrowse link 10 86,520,779 86,540,730 RGD:1600115
G Cby1 chibby homolog 1 (Drosophila) GBrowse link 7 120,882,298 120,888,691 RGD:1600115
G Ccnl1 cyclin L1 GBrowse link 2 177,110,678 177,122,977 RGD:632453
G Ccnl2 cyclin L2 GBrowse link 5 176,731,925 176,743,703 RGD:1600115
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 GBrowse link 1 205,629,176 205,633,588 RGD:1600115
RGD:1624291
G Cdc5l cell division cycle 5-like GBrowse link 9 16,838,171 16,876,921 RGD:619664
RGD:1624291
G Cdk12 cyclin-dependent kinase 12 GBrowse link 10 85,953,855 86,019,907 RGD:1624291
RGD:8553775
G Cdk13 cyclin-dependent kinase 13 GBrowse link 17 47,889,843 47,979,627 RGD:1600115
RGD:1624291
G Cir1 corepressor interacting with RBPJ, 1 GBrowse link 3 66,478,181 66,507,756 RGD:1600115
G Csnk1a1 casein kinase 1, alpha 1 GBrowse link 18 56,116,635 56,139,523 RGD:1600115
RGD:1624291
G Cwc22 CWC22 spliceosome-associated protein GBrowse link 3 71,298,090 71,346,831 RGD:1624291
G Cxxc1 CXXC finger protein 1 GBrowse link 18 69,335,221 69,340,567 RGD:1600115
RGD:1624291
G Ddx39b DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B GBrowse link 20 6,886,503 6,898,979 RGD:1600115
G Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 GBrowse link 17 11,582,729 11,626,991 RGD:1600115
G Dgkq diacylglycerol kinase, theta GBrowse link 14 2,064,851 2,078,913 RGD:1600115
RGD:1624291
G Dusp11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) GBrowse link 4 182,370,260 182,387,183 RGD:1600115
G Dyrk1a dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A GBrowse link 11 38,453,019 38,550,512 RGD:8554210
RGD:8554265
G Eaf2 ELL associated factor 2 GBrowse link 11 69,969,912 70,013,412 RGD:1600115
G Eftud2 elongation factor Tu GTP binding domain containing 2 GBrowse link 10 90,705,838 90,756,354 RGD:1600115
RGD:1624291
G Eif4a3 eukaryotic translation initiation factor 4A3 GBrowse link 10 108,027,035 108,037,029 RGD:1600115
G Ell elongation factor RNA polymerase II GBrowse link 16 20,449,838 20,497,154 RGD:1600115
RGD:1624291
G Ep400 E1A binding protein p400 GBrowse link 12 53,687,001 53,793,502 RGD:1600115
RGD:1624291
G Fastk Fas-activated serine/threonine kinase GBrowse link 4 7,271,900 7,275,954 RGD:1624291
G Fto fat mass and obesity associated GBrowse link 19 27,803,098 28,182,268 RGD:1600115
RGD:1624291
G Fyttd1 forty-two-three domain containing 1 GBrowse link 11 74,198,837 74,221,579 RGD:1600115
RGD:1624291
G Gli2 GLI family zinc finger 2 GBrowse link 13 39,955,094 40,170,750 RGD:1600115
RGD:1624291
G Gli3 GLI family zinc finger 3 GBrowse link 17 50,360,049 50,629,477 RGD:1600115
RGD:1624291
RGD:2290270
G Glis2 GLIS family zinc finger 2 GBrowse link 10 9,919,818 9,940,224 RGD:1600115
RGD:1624291
G Hipk1 homeodomain interacting protein kinase 1 GBrowse link 2 225,647,725 225,698,674 RGD:1600115
RGD:1624291
G Hspa1a heat shock protein 1A GBrowse link 20 6,956,234 6,962,151 RGD:1600115
RGD:1624291
G Hspa1b heat shock protein 1B GBrowse link 20
20
7,029,038
4,802,576
7,033,025
4,804,849
RGD:1600115
RGD:1624291
G LOC100910172 brain acid soluble protein 1-like GBrowse link 9 3,228,988 3,230,220 RGD:1600115
RGD:1624291
G LOC100910660 serine/arginine-rich splicing factor 3-like GBrowse link 17 1,897,381 1,898,225 RGD:1600115
RGD:1624291
G LOC361990 similar to DKFZP547E1010 protein GBrowse link 2 209,318,314 209,330,501 RGD:1624291
G Magoh mago-nashi homolog, proliferation-associated (Drosophila) GBrowse link 5 131,328,623 131,335,513 RGD:1600115
G Mbd1 methyl-CpG binding domain protein 1 GBrowse link 18 69,390,120 69,404,741 RGD:1600115
RGD:1624291
G Mecom MDS1 and EVI1 complex locus GBrowse link 2 137,080,581 137,665,758 RGD:1600115
RGD:1624291
G Mef2c myocyte enhancer factor 2C GBrowse link 2 11,521,053 11,684,949 RGD:1600115
RGD:1624291
G Meox2 mesenchyme homeobox 2 GBrowse link 6 66,231,865 66,293,008 RGD:1600115
G Mettl3 methyltransferase-like 3 GBrowse link 15 32,520,500 32,531,328 RGD:1600115
RGD:1624291
G Nek6 NIMA-related kinase 6 GBrowse link 3 28,037,221 28,114,175 RGD:1600115
G Noc3l nucleolar complex associated 3 homolog (S. cerevisiae) GBrowse link 1 264,962,014 264,990,545 RGD:1600115
RGD:1624291
G Nono non-POU domain containing, octamer-binding GBrowse link X 72,175,019 72,192,921 RGD:1600115
G Npm1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) GBrowse link 10 17,965,977 17,975,978 RGD:1600115
RGD:1624291
G Nrip1 nuclear receptor interacting protein 1 GBrowse link 11 18,314,226 18,397,564 RGD:1624291
G Nsrp1 nuclear speckle splicing regulatory protein 1 GBrowse link 10 62,796,501 62,829,735 RGD:1600115
RGD:1624291
G Nxf1 nuclear RNA export factor 1 GBrowse link 1 231,895,708 231,908,901 RGD:1600115
RGD:1624291
G Ogg1 8-oxoguanine DNA glycosylase GBrowse link 4 208,580,193 208,586,457 RGD:1600115
RGD:1624291
G Patl1 protein associated with topoisomerase II homolog 1 (yeast) GBrowse link 1 235,401,989 235,433,952 RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 GBrowse link 12 11,609,488 11,614,655 RGD:1624291
G Phf5a PHD finger protein 5A GBrowse link 7 123,070,681 123,077,246 RGD:1600115
RGD:1624291
G Pias2 protein inhibitor of activated STAT, 2 GBrowse link 18 73,147,273 73,203,947 RGD:1600115
G Pias3 protein inhibitor of activated STAT, 3 GBrowse link 2 218,309,595 218,318,467 RGD:1600115
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha GBrowse link 2 215,722,370 215,765,396 RGD:1600115
RGD:1624291
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 134,211,557 134,908,321 RGD:1600115
RGD:1624291
G Plrg1 pleiotropic regulator 1 GBrowse link 2 201,454,958 201,471,289 RGD:1600115
G Pnn pinin, desmosome associated protein GBrowse link 6 89,685,236 89,693,549 RGD:1600115
RGD:1624291
G Poldip3 polymerase (DNA-directed), delta interacting protein 3 GBrowse link 7 123,974,866 124,003,533 RGD:1624291
G Ppig peptidylprolyl isomerase G GBrowse link 3 62,571,744 62,600,516 RGD:1600115
G Ppih peptidylprolyl isomerase H (cyclophilin H) GBrowse link 5 142,160,007 142,178,024 RGD:1600115
RGD:1624291
G Ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme GBrowse link 12 41,744,531 41,762,059 RGD:1600115
G Ppp1r8 protein phosphatase 1, regulatory subunit 8 GBrowse link 5 154,679,822 154,696,564 RGD:1600115
RGD:1624291
G Pqbp1 polyglutamine binding protein 1 GBrowse link X 16,229,838 16,234,365 RGD:1600115
RGD:1624291
G Prpf18 pre-mRNA processing factor 18 GBrowse link 17 79,256,708 79,287,301 RGD:1600115
G Prpf19 pre-mRNA processing factor 19 GBrowse link 1 234,012,625 234,023,696 RGD:1600115
RGD:1624291
G Prpf31 pre-mRNA processing factor 31 GBrowse link 1 63,143,068 63,154,743 RGD:1600115
RGD:1624291
G Prpf6 pre-mRNA processing factor 6 GBrowse link 3 180,807,600 180,871,661 RGD:1600115
G Pspc1 paraspeckle component 1 GBrowse link 15 40,799,244 40,883,016 RGD:1600115
G Rbm11 RNA binding motif protein 11 GBrowse link 11 17,664,383 17,674,391 RGD:1600115
RGD:1624291
G Rbm25 RNA binding motif protein 25 GBrowse link 6 118,377,074 118,423,642 RGD:1624291
G Rbm4 RNA binding motif protein 4 GBrowse link 1 226,903,520 226,913,901 RGD:1600115
RGD:1624291
G Rbm4b RNA binding motif protein 4B GBrowse link 1 226,874,161 226,921,371 RGD:1600115
G Rbm8a RNA binding motif protein 8A GBrowse link 2 218,242,195 218,244,962 RGD:1600115
G Ring1 ring finger protein 1 GBrowse link 20 5,891,721 5,895,165 RGD:1600115
G Rnf34 ring finger protein 34, E3 ubiquitin protein ligase GBrowse link 12 41,057,289 41,078,204 RGD:1600115
G Rnps1 ribonucleic acid binding protein S1 GBrowse link 10 13,603,258 13,613,706 RGD:1600115
G Rsrc1 arginine/serine-rich coiled-coil 1 GBrowse link 2
2
2
183,478,536
183,573,497
183,840,728
183,493,424
183,803,891
183,881,362
RGD:1600115
RGD:1624291
G Sap18 Sin3-associated polypeptide 18 GBrowse link 15 41,910,111 41,914,416 RGD:1624291
G Sarnp SAP domain containing ribonucleoprotein GBrowse link 7 3,217,778 3,271,845 RGD:1600115
RGD:1624291
G Slu7 SLU7 splicing factor homolog (S. cerevisiae) GBrowse link 10 28,871,433 28,886,835 RGD:1304333
RGD:1624291
G Smndc1 survival motor neuron domain containing 1 GBrowse link 1 281,509,724 281,520,796 RGD:1600115
G Son Son DNA binding protein GBrowse link 11 35,415,323 35,446,502 RGD:1600115
RGD:1624291
G Spop speckle-type POZ protein GBrowse link 10 83,040,592 83,121,901 RGD:1600115
RGD:1624291
G Sprtn SprT-like N-terminal domain GBrowse link 19 68,363,163 68,370,397 RGD:1600115
RGD:1624291
G Srp54a signal recognition particle 54A GBrowse link 6 85,532,350 85,572,100 RGD:1600115
G Srrm2 serine/arginine repetitive matrix 2 GBrowse link 10 12,948,282 12,982,941 RGD:1600115
RGD:1624291
G Srsf1 serine/arginine-rich splicing factor 1 GBrowse link 10 74,759,412 74,765,821 RGD:1600115
RGD:1624291
G Srsf2 serine/arginine-rich splicing factor 2 GBrowse link 10 105,451,332 105,454,538 RGD:1600115
RGD:1624291
G Srsf3 serine/arginine-rich splicing factor 3 GBrowse link 20 8,534,919 8,544,852 RGD:1600115
G Srsf5 serine/arginine-rich splicing factor 5 GBrowse link 17
6
21,149,626
112,776,230
21,149,932
112,805,142
RGD:1600115
RGD:1624291
G Srsf6 serine/arginine-rich splicing factor 6 GBrowse link 3 165,502,385 165,507,708 RGD:1600115
RGD:1624291
G Sry sex determining region Y RGD:1600115
G Sumo1 small ubiquitin-like modifier 1 GBrowse link 9 66,258,853 66,288,103 RGD:1600115
G Tardbp TAR DNA binding protein GBrowse link 5 169,088,684 169,099,216 RGD:5687141
G Tfip11 tuftelin interacting protein 11 GBrowse link 12 52,077,898 52,090,133 RGD:1600115
RGD:1624291
G Thap7 THAP domain containing 7 GBrowse link 11 90,450,724 90,453,825 RGD:1600115
RGD:1624291
G Thoc1 THO complex 1 GBrowse link 18 1,185,400 1,220,171 RGD:1600115
G Thoc5 THO complex 5 GBrowse link 14 85,816,054 85,849,564 RGD:1600115
G Thoc6 THO complex 6 homolog (Drosophila) GBrowse link 10 12,812,180 12,817,540 RGD:1600115
G Timm50 translocase of inner mitochondrial membrane 50 GBrowse link 1 86,684,416 86,691,956 RGD:1600115
RGD:1624291
G Topors topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase GBrowse link 5 61,098,846 61,110,393 RGD:1600115
RGD:1624291
G Trim69 tripartite motif-containing 69 GBrowse link 3 120,642,563 120,663,689 RGD:1600115
RGD:1624291
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific GBrowse link 1 232,088,997 232,100,065 RGD:1600115
RGD:1624291
G U2af1 U2 small nuclear RNA auxiliary factor 1 GBrowse link 20 12,582,585 12,593,487 RGD:1600115
RGD:1624291
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 GBrowse link 1 90,172,229 90,174,953 RGD:1600115
G U2af2 U2 small nuclear RNA auxiliary factor 2 GBrowse link 1 76,206,254 76,223,269 RGD:1600115
RGD:1624291
G Wbp11 WW domain binding protein 11 GBrowse link 4 234,414,445 234,427,903 RGD:1624291
G Wbp4 WW domain binding protein 4 GBrowse link 15 65,410,539 65,436,878 RGD:1600115
RGD:1624291
G Wt1 Wilms tumor 1 GBrowse link 3 101,756,056 101,802,601 RGD:1600115
RGD:1624291
G Wtap Wilms tumor 1 associated protein GBrowse link 1 51,781,701 51,806,726 RGD:1600115
RGD:1624291
G Ylpm1 YLP motif containing 1 GBrowse link 6 116,659,698 116,736,133 RGD:1600115
G Zbtb16 zinc finger and BTB domain containing 16 GBrowse link 8 51,573,252 51,740,759 RGD:1600115
RGD:1624291
G Zc3h14 zinc finger CCCH type containing 14 GBrowse link 6 131,951,431 131,988,793 RGD:1600115
G Zcchc12 zinc finger, CCHC domain containing 12 GBrowse link X 122,958,348 122,961,547 RGD:1600115
RGD:1624291
G Zcchc18 zinc finger, CCHC domain containing 18 GBrowse link X 107,513,884 107,515,459 RGD:1600115
G Zfp830 zinc finger protein 830 GBrowse link 10 69,748,958 69,750,422 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 298162
    organelle part 54200
      intracellular organelle part 51899
        nuclear part 23744
          nucleoplasm part 3664
            nuclear body 1349
              nuclear speck 525
                omega speckle 0
Path 2
Term Annotations click to browse term
  cellular_component 298162
    cell 211976
      cell part 210852
        intracellular 163253
          intracellular part 160137
            intracellular organelle 112407
              intracellular membrane-bounded organelle 92077
                nucleus 51127
                  nuclear part 23744
                    nuclear lumen 19174
                      nucleoplasm 11380
                        nucleoplasm part 3664
                          nuclear body 1349
                            nuclear speck 525
                              omega speckle 0
paths to the root