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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased CD8-positive, naive alpha-beta T cell number
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Accession:MP:0013435 term browser browse the term
Definition:reduction in the number of the naïve regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions with a CD44-low CD62L+ phenotype
Synonyms:exact_synonym: reduced CD8-positive, naive alpha-beta T cell number


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decreased CD8-positive, naive alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein IEA MGI NCBI chr 2:22,645,983...22,765,671
Ensembl chr 2:22,664,106...22,765,665 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 IAGP MGI PMID:33719206 NCBI chr10:79,852,505...79,867,305
Ensembl chr10:79,852,487...79,867,306 		JBrowse link
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Bcap31 B cell receptor associated protein 31 IAGP MGI PMID:28333124 NCBI chr  X:72,729,784...72,761,464
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G Casp8 caspase 8 IEA MGI NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide IEA MGI NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cd8b1 CD8 subunit beta 1 IEA MGI NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Clock clock circadian regulator IEA MGI NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA MGI NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Dcaf12 DDB1 and CUL4 associated factor 12 IEA MGI NCBI chr 4:41,291,300...41,316,749
Ensembl chr 4:41,291,300...41,314,889 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Ess2 ess-2 splicing factor IAGP MGI PMID:35933014 NCBI chr16:17,718,573...17,729,225
Ensembl chr16:17,718,573...17,729,212 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IAGP MGI PMID:23443560 NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IEA MGI NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lepr leptin receptor IEA MGI NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IEA MGI NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lmbr1l limb region 1 like IAGP MGI PMID:31073040 NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112 		JBrowse link
G Nckap1l NCK associated protein 1 like IEA MGI NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 IEA MGI NCBI chr 5:63,806,446...63,967,889
Ensembl chr 5:63,806,445...63,967,889 		JBrowse link
G Plag1 pleiomorphic adenoma gene 1 IEA MGI NCBI chr 4:3,895,209...3,938,429
Ensembl chr 4:3,900,996...3,938,423 		JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA MGI NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IEA MGI NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rag1 recombination activating 1 IEA MGI NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rorc RAR-related orphan receptor gamma IEA MGI NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IEA MGI NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 IEA MGI NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IEA MGI NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 IEA MGI NCBI chr 2:128,768,188...128,786,018
Ensembl chr 2:128,768,188...128,785,997 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    hematopoietic system phenotype 5459
      abnormal hematopoietic system morphology/development 4999
        abnormal hematopoietic cell morphology 4182
          abnormal hematopoietic cell number 3008
            abnormal leukocyte cell number 2499
              abnormal lymphocyte cell number 1676
                abnormal T cell number 1056
                  abnormal alpha-beta T cell number 685
                    abnormal CD8-positive, alpha-beta T cell number 461
                      abnormal CD8-positive, naive alpha-beta T cell number 63
                        decreased CD8-positive, naive alpha-beta T cell number 53
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    immune system phenotype 5613
      abnormal immune system morphology 4014
        abnormal immune system cell morphology 2804
          abnormal leukocyte morphology 2783
            abnormal mononuclear cell morphology 2239
              abnormal lymphocyte morphology 1813
                abnormal T cell morphology 1151
                  abnormal alpha-beta T cell morphology 870
                    abnormal alpha-beta T cell number 685
                      abnormal CD8-positive, alpha-beta T cell number 461
                        abnormal CD8-positive, naive alpha-beta T cell number 63
                          decreased CD8-positive, naive alpha-beta T cell number 53
paths to the root