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ONTOLOGY REPORT - ANNOTATIONS


Term:acyl-CoA biosynthetic process
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Accession:GO:0071616 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
Synonyms:exact_synonym: acyl-CoA anabolism;   acyl-CoA biosynthesis;   acyl-CoA formation;   acyl-CoA synthesis



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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acly ATP citrate lyase involved_in NAS
IEA
ISO
IBA
GO_REF:0000107
(PMID:1371749)
PMID:21873635
GO_REF:0000002
Ensembl
RGD
InterPro
PMID:1371749 PMID:2295639 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:631761, RGD:13792537 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:16788062)
(MGI:2151932|PMID:11150295)
RGD PMID:11150295 PMID:16788062 MGI:2151932 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 acts_upstream_of_or_within ISO (MGI:2151932|PMID:11150295) RGD PMID:11150295 MGI:2151932 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Dip2a disco-interacting protein 2 homolog A involved_in ISO (MGI:6478983|PMID:30672040) RGD PMID:30672040 MGI:6478983 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217
JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in IDA
IEA
ISO
IBA
GO_REF:0000041
(PMID:10417274), (PMID:10455107), (PMID:9869665)
PMID:21873635
UniProt
RGD
PMID:9869665 PMID:10417274 PMID:10455107 PMID:17316539 PMID:21873635 GO_REF:0000041, RGD:1600790, RGD:13792537 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO (PMID:29754768) RGD PMID:29754768 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in IDA
ISO
IBA
(PMID:24534072)
PMID:21873635
RGD PMID:24534072 PMID:7487891 PMID:21873635 RGD:1599112, RGD:13792537 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in IDA
ISO
(PMID:24534072) RGD PMID:24534072 PMID:7487891 RGD:1599112 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in IDA
ISO
IBA
IEA
(PMID:19081061), (PMID:24534072)
PMID:21873635
GO_REF:0000002
RGD
InterPro
PMID:19081061 PMID:24534072 PMID:7487891 PMID:21873635 GO_REF:0000002, RGD:1599112, RGD:13792537 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:82,511,483...82,514,378
Ensembl chr16:82,511,511...82,514,372
JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7487891 PMID:21873635 RGD:1599112, RGD:13792537 NCBI chr 2:229,872,300...229,873,848 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta involved_in IDA
ISO
IEA
IBA
(PMID:19081061), (PMID:24534072)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:19081061 PMID:24534072 PMID:7487891 PMID:21873635 GO_REF:0000107, RGD:1599112, RGD:13792537 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X involved_in IEA
ISO
GO_REF:0000108
(PMID:24534072)
GOC
RGD
PMID:24534072 GO_REF:0000108 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 TAS RGD PMID:12435272 RGD:729541 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-CoA dehydrogenase involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:6895440 PMID:21873635 RGD:1598697, RGD:13792537 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in IGI
IBA
PMID:21873635 RGD
GO_Central
PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in IGI
IBA
PMID:21873635 RGD
GO_Central
PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 involved_in IGI
IBA
PMID:21873635 RGD
GO_Central
PMID:16466685 PMID:21873635 RGD:2312800, RGD:13792537 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845
JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in IEA
ISO
GO_REF:0000041
(MGI:3804564|PMID:18487439)
UniProt
RGD
PMID:18487439 GO_REF:0000041 MGI:3804564 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpc1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within ISO (MGI:5428352|PMID:22628558) RGD PMID:22628558 MGI:5428352 NCBI chr 1:52,437,745...52,449,369
Ensembl chr 1:52,437,741...52,449,400
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within ISO MGI:5635078 (MGI:5428352|PMID:22628558), (MGI:5576400|PMID:24910426) RGD PMID:22628558 PMID:24910426 MGI:5428352 MGI:5576400 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 acts_upstream_of_or_within ISO MGI:2182095|MGI:2386703 (MGI:3817854|PMID:18586888) RGD PMID:18586888 MGI:3817854 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5487511|PMID:22195962)
Ensembl
RGD
PMID:22195962 GO_REF:0000107 MGI:5487511 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5428826|PMID:22360721)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22360721 GO_REF:0000024 GO_REF:0000107 MGI:5428826 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:58,477,471...58,553,932
Ensembl chr  X:58,486,554...58,553,557
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3692363|PMID:16606348)
GO_REF:0000024
(PMID:21852536)
Ensembl
RGD
UniProt
PMID:16606348 PMID:21852536 GO_REF:0000024 GO_REF:0000107 MGI:3692363 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (MGI:3628986|PMID:16636270), (MGI:3629421|PMID:16734431) RGD PMID:16636270 PMID:16734431 MGI:3628986 MGI:3629421 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        thioester metabolic process 91
          acyl-CoA metabolic process 91
            acyl-CoA biosynthetic process 34
              2-hydroxybenzoyl-CoA biosynthetic process 0
              L-methylmalonyl-CoA biosynthetic process 0
              acetyl-CoA biosynthetic process + 20
              benzoyl-CoA biosynthetic process 0
              fatty-acyl-CoA biosynthetic process + 11
              malonyl-CoA biosynthetic process 2
              propionyl-CoA biosynthetic process 1
              regulation of acyl-CoA biosynthetic process + 5
              succinyl-CoA biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        cellular aromatic compound metabolic process 5635
          nucleobase-containing compound metabolic process 5410
            nucleobase-containing small molecule metabolic process 572
              nucleoside phosphate metabolic process 505
                nucleoside phosphate biosynthetic process 243
                  nucleotide biosynthetic process 240
                    ribonucleotide biosynthetic process 181
                      purine ribonucleotide biosynthetic process 167
                        acyl-CoA biosynthetic process 34
                          2-hydroxybenzoyl-CoA biosynthetic process 0
                          L-methylmalonyl-CoA biosynthetic process 0
                          acetyl-CoA biosynthetic process + 20
                          benzoyl-CoA biosynthetic process 0
                          fatty-acyl-CoA biosynthetic process + 11
                          malonyl-CoA biosynthetic process 2
                          propionyl-CoA biosynthetic process 1
                          regulation of acyl-CoA biosynthetic process + 5
                          succinyl-CoA biosynthetic process 0
paths to the root