Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:acyl-CoA biosynthetic process
go back to main search page
Accession:GO:0071616 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
Synonyms:exact_synonym: acyl-CoA anabolism;   acyl-CoA biosynthesis;   acyl-CoA formation;   acyl-CoA synthesis


show annotations for term's descendants           Sort by:
acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO
IEA		 (PMID:17371050)
GO_REF:0000107		 RGD
Ensembl		 PMID:17371050 GO_REF:0000107 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acly ATP citrate lyase involved_in NAS
ISO
IBA
IEA		 (PMID:1371749), (PMID:39881208)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002		 RGD
GO_Central
Ensembl
InterPro		 PMID:1371749 PMID:39881208 PMID:2295639 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:631761 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:16788062)
GO_REF:0000107
GO_REF:0000033
(PMID:11150295)		 RGD
Ensembl
GO_Central		 PMID:11150295 PMID:16788062 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11150295)
GO_REF:0000033		 RGD
GO_Central		 PMID:11150295 GO_REF:0000033 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A involved_in ISO (PMID:30672040) RGD PMID:30672040 NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
GO_REF:0000041
(PMID:10417274), (PMID:10455107), (PMID:9869665)		 Ensembl
GO_Central
UniProt
RGD		 PMID:9869665 PMID:10417274 PMID:10455107 PMID:17316539 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107, RGD:1600790 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO
IEA		 (PMID:29754768)
GO_REF:0000107		 RGD
Ensembl		 PMID:29754768 GO_REF:0000107 NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:133,023,121...133,026,933 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-CoA dehydrogenase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:6895440 GO_REF:0000033, RGD:1598697 NCBI chr19:40,168,038...40,174,536
Ensembl chr19:23,263,264...23,269,681 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:137,246,781...137,251,351
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:93,582,930...93,609,479
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in IEA
ISO		 GO_REF:0000041
(PMID:18487439)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18487439 GO_REF:0000041 GO_REF:0000107 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgk1 phosphoglycerate kinase 1 involved_in ISO
IEA		 (PMID:26942675)
GO_REF:0000107		 RGD
Ensembl		 PMID:26942675 GO_REF:0000107 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:44,487,980...44,489,330
Ensembl chr 2:42,754,639...42,755,856 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO
IEA		 (PMID:17371050)
GO_REF:0000107		 RGD
Ensembl		 PMID:17371050 GO_REF:0000107 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
pyruvate decarboxylation to acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in IDA
IEA
ISO
IBA		 GO_REF:0000107
GO_REF:0000002
GO_REF:0000117
MGI:2386703 (PMID:17314311), (PMID:27621431)
GO_REF:0000033
(PMID:24534072)		 Ensembl
InterPro
UniProt
RGD
GO_Central		 PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:1599112 NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in IDA
IEA
ISO		 GO_REF:0000107
MGI:2386703 (PMID:17314311), (PMID:27621431)
(PMID:24534072)		 Ensembl
RGD		 PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 GO_REF:0000107, RGD:1599112 NCBI chr 6:53,631,686...53,655,059
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) RGD PMID:22628558 NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:22628558)
GO_REF:0000107
MGI:5635078 (PMID:22628558), (PMID:24910426)		 RGD
Ensembl		 PMID:22628558 PMID:24910426 GO_REF:0000107 NCBI chr13:80,261,143...80,280,668
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000117
MGI:2182095|MGI:2386703 (PMID:18586888)
GO_REF:0000033
GO_REF:0000114
(PMID:19081061), (PMID:24534072)		 InterPro
UniProt
RGD
GO_Central
ComplexPortal		 PMID:18586888 PMID:19081061 PMID:24534072 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000114 GO_REF:0000117, RGD:1599112 NCBI chr  X:38,509,158...38,522,986
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000117
GO_REF:0000002		 GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117 NCBI chr16:89,213,172...89,216,067
Ensembl chr16:82,511,511...82,514,372 		JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in IDA
IEA
IBA		 GO_REF:0000117
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central
RGD		 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117, RGD:1599112 NCBI chr 2:232,545,550...232,547,098 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta involved_in IDA
IBA
ISO
IEA		 GO_REF:0000033
GO_REF:0000114
GO_REF:0000002
(PMID:19081061), (PMID:24534072)
GO_REF:0000107		 GO_Central
ComplexPortal
InterPro
RGD
Ensembl		 PMID:19081061 PMID:24534072 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114, RGD:1599112 NCBI chr15:19,182,789...19,188,731
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X involved_in ISO
IEA		 (PMID:24534072)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000117
MGI:2386703 (PMID:17314311), (PMID:27621431)		 RGD
Ensembl
InterPro
UniProt		 PMID:17314311 PMID:24534072 PMID:27621431 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:109,826,579...109,886,869
Ensembl chr 3:89,371,497...89,431,773 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 TAS RGD PMID:12435272 RGD:729541 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:22195962)		 Ensembl
GO_Central
RGD		 PMID:22195962 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:22360721)		 UniProt
GO_Central
RGD		 PMID:22360721 GO_REF:0000024 GO_REF:0000033 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:62,480,535...62,547,371
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO
IBA
IEA
ISS		 (PMID:21852536)
GO_REF:0000033
(PMID:16606348)
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:16606348 PMID:21852536 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in ISO
IEA		 (PMID:38547260)
GO_REF:0000107		 RGD
Ensembl		 PMID:38547260 GO_REF:0000107 NCBI chr 4:73,170,125...73,557,683
Ensembl chr 4:72,170,134...72,557,694 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO
IEA		 MGI:2389489 (PMID:16636270), (PMID:16734431)
GO_REF:0000107		 RGD
Ensembl		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmaa metabolism of cobalamin associated A acts_upstream_of_or_within ISO (PMID:7904153) RGD PMID:7904153 NCBI chr19:45,523,352...45,553,602
Ensembl chr19:28,619,087...28,649,319 		JBrowse link
G Mmut methylmalonyl-CoA mutase involved_in ISO
IEA		 (PMID:7904153)
GO_REF:0000107		 RGD
Ensembl		 PMID:7904153 GO_REF:0000107 NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        biosynthetic process 8676
          amide biosynthetic process 166
            acyl-CoA biosynthetic process 40
              2-hydroxybenzoyl-CoA biosynthetic process 0
              L-methylmalonyl-CoA biosynthetic process 0
              acetyl-CoA biosynthetic process + 24
              benzoyl-CoA biosynthetic process 0
              fatty-acyl-CoA biosynthetic process + 12
              malonyl-CoA biosynthetic process 2
              regulation of acyl-CoA biosynthetic process + 9
              succinyl-CoA biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        primary metabolic process 10763
          nucleobase-containing compound metabolic process 5900
            nucleobase-containing small molecule metabolic process 733
              nucleoside phosphate metabolic process 699
                acyl-CoA metabolic process 99
                  acyl-CoA biosynthetic process 40
                    2-hydroxybenzoyl-CoA biosynthetic process 0
                    L-methylmalonyl-CoA biosynthetic process 0
                    acetyl-CoA biosynthetic process + 24
                    benzoyl-CoA biosynthetic process 0
                    fatty-acyl-CoA biosynthetic process + 12
                    malonyl-CoA biosynthetic process 2
                    regulation of acyl-CoA biosynthetic process + 9
                    succinyl-CoA biosynthetic process 2
paths to the root