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ONTOLOGY REPORT - ANNOTATIONS


Term:acetyl-CoA biosynthetic process
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Accession:GO:0006085 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
Synonyms:exact_synonym: acetyl-CoA anabolism;   acetyl-CoA biosynthesis;   acetyl-CoA formation;   acetyl-CoA synthesis
 xref: MetaCyc:PWY-5173


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Acly ATP citrate lyase NAS
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:1371749)
GO_REF:0000002
Ensembl
RGD
InterPro
PMID:1371749, PMID:2295639, PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:631761, RGD:13792537 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 ISO (PMID:16788062)
(MGI:2151932|PMID:11150295)
RGD PMID:11150295 PMID:16788062 MGI:2151932 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 ISO (MGI:2151932|PMID:11150295) RGD PMID:11150295 MGI:2151932 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Mlycd malonyl-CoA decarboxylase IDA
IBA
ISO
IEA
PMID:21873635
(PMID:10417274), (PMID:10455107), (PMID:9869665)
GO_REF:0000041
RGD
UniProt
PMID:9869665 PMID:10417274 PMID:10455107, PMID:17316539, PMID:21873635 GO_REF:0000041, RGD:1600790, RGD:13792537 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase ISO (PMID:29754768) RGD PMID:29754768 NCBI chr 5:138,466,298...138,470,108
Ensembl chr 5:138,466,293...138,470,096
JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293
JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7487891, PMID:21873635 RGD:1599112, RGD:13792537 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dld dihydrolipoamide dehydrogenase IDA RGD PMID:7487891 RGD:1599112 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 IDA
IBA
ISO
IEA
PMID:21873635
(PMID:19081061)
GO_REF:0000002
RGD
InterPro
PMID:19081061, PMID:7487891, PMID:21873635 GO_REF:0000002, RGD:1599112, RGD:13792537 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410
JBrowse link
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:88,344,440...88,347,335
Ensembl chr16:88,345,247...88,347,369
JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:7487891, PMID:21873635 RGD:1599112, RGD:13792537 NCBI chr 2:246,736,449...246,737,997
Ensembl chr 2:246,736,459...246,737,997
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta IDA
IBA
ISO
IEA
PMID:21873635
(PMID:19081061)
GO_REF:0000107
RGD
Ensembl
PMID:19081061, PMID:7487891, PMID:21873635 GO_REF:0000107, RGD:1599112, RGD:13792537 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:92,910,300...92,933,725
Ensembl chr 3:92,909,725...92,969,050
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 TAS RGD PMID:12435272 RGD:729541 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
mitochondrial acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpc1 mitochondrial pyruvate carrier 1 ISO (MGI:5428352|PMID:22628558) RGD PMID:22628558 MGI:5428352 NCBI chr 1:53,026,608...53,038,229
Ensembl chr 1:53,026,608...53,038,229
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 ISO MGI:5635078 (MGI:5428352|PMID:22628558), (MGI:5576400|PMID:24910426) RGD PMID:22628558 PMID:24910426 MGI:5428352 MGI:5576400 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 ISO MGI:2182095|MGI:2386703 (MGI:3817854|PMID:18586888) RGD PMID:18586888 MGI:3817854 NCBI chr  X:37,329,779...37,343,410
Ensembl chr  X:37,329,779...37,343,410
JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 IEA
ISO
GO_REF:0000107
(MGI:5487511|PMID:22195962)
Ensembl
RGD
PMID:22195962 GO_REF:0000107 MGI:5487511 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 IEA
ISO
ISS
GO_REF:0000107
(MGI:5428826|PMID:22360721)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22360721 GO_REF:0000024 GO_REF:0000107 MGI:5428826 NCBI chr10:82,838,270...82,852,758
Ensembl chr10:82,839,153...82,852,660
JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:62,836,131...62,904,114
Ensembl chr  X:62,836,131...62,903,554
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 IEA
ISO
ISS
GO_REF:0000107
(MGI:3692363|PMID:16606348)
GO_REF:0000024
(PMID:21852536)
Ensembl
RGD
UniProt
PMID:16606348 PMID:21852536 GO_REF:0000024 GO_REF:0000107 MGI:3692363 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      organic substance metabolic process 11552
        thioester metabolic process 89
          acyl-CoA metabolic process 89
            acetyl-CoA metabolic process 37
              acetyl-CoA biosynthetic process 19
                acetyl-CoA biosynthetic process from acetate 1
                acetyl-CoA biosynthetic process from ethanol 0
                acetyl-CoA biosynthetic process from pantothenate 0
                acetyl-CoA biosynthetic process from pyruvate + 13
                carbon fixation by acetyl-CoA pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      cellular metabolic process 10964
        cellular aromatic compound metabolic process 5688
          nucleobase-containing compound metabolic process 5476
            nucleobase-containing small molecule metabolic process 591
              nucleoside phosphate metabolic process 517
                nucleotide metabolic process 510
                  ribonucleotide metabolic process 419
                    purine ribonucleotide metabolic process 401
                      purine ribonucleotide biosynthetic process 172
                        acyl-CoA biosynthetic process 34
                          acetyl-CoA biosynthetic process 19
                            acetyl-CoA biosynthetic process from acetate 1
                            acetyl-CoA biosynthetic process from ethanol 0
                            acetyl-CoA biosynthetic process from pantothenate 0
                            acetyl-CoA biosynthetic process from pyruvate + 13
                            carbon fixation by acetyl-CoA pathway 0
paths to the root