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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of cartilage development
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Accession:GO:0061036 term browser browse the term
Definition:Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.


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positive regulation of cartilage development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp1 bone morphogenetic protein 1 acts_upstream_of_or_within ISO (PMID:3201241) RGD PMID:3201241 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA		 (MGI:5621263|PMID:19956691)
GO_REF:0000107		 RGD
Ensembl		 PMID:19956691 GO_REF:0000107 MGI:5621263 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:3201241)
(PMID:10684250)		 Ensembl
RGD		 PMID:3201241 PMID:10684250 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:3201241)
GO_REF:0000107		 RGD
Ensembl		 PMID:3201241 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:9441684) RGD PMID:9441684 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (MGI:5621263|PMID:19956691) RGD PMID:19956691 MGI:5621263 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Mdk midkine involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5693192|PMID:25551381)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25551381 GO_REF:0000024 GO_REF:0000107 MGI:5693192 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:1343990|PMID:10477299) RGD PMID:10477299 MGI:1343990 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19251704)		 Ensembl
RGD		 PMID:19251704 GO_REF:0000107 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405) RGD PMID:21401405 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:21401405), (PMID:29503843)
(PMID:19047045)
GO_REF:0000024		 RGD
UniProt		 PMID:19047045 PMID:21401405 PMID:29503843 GO_REF:0000024 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18991062)		 Ensembl
RGD		 PMID:18991062 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS		 (PMID:21547890)
GO_REF:0000024		 RGD
UniProt		 PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (PMID:14668414) RGD PMID:14668414 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (PMID:14668414) RGD PMID:14668414 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 IDA RGD PMID:23077084 RGD:7242190 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95524 (PMID:15781473)		 Ensembl
RGD		 PMID:15781473 GO_REF:0000107 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:21976273), (PMID:24098149)
MGI:1927616 (PMID:18363966), (PMID:9885252)		 RGD PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612 		JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
ISS		 (PMID:26643732)
GO_REF:0000024		 RGD
UniProt		 PMID:26643732 GO_REF:0000024 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:1856276 (PMID:17328886) RGD PMID:17328886 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (PMID:14668414) RGD PMID:14668414 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (PMID:14668414) RGD PMID:14668414 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5320274|PMID:21071451)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21071451 GO_REF:0000024 GO_REF:0000107 MGI:5320274 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (PMID:19410023) RGD PMID:19410023 NCBI chr16:6,072,908...6,075,161
Ensembl chr16:6,072,833...6,075,161 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) RGD PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 IGI RGD PMID:15466490 RGD:150429792 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:17884819 RGD:2298851 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (PMID:10072783)		 Ensembl
RGD		 PMID:10072783 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (MGI:5285145|PMID:21035443) RGD PMID:21035443 MGI:5285145 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO
IBA		 (PMID:21401405)
GO_REF:0000033
(MGI:5285147|PMID:20940257)		 RGD
GO_Central		 PMID:20940257 PMID:21401405 GO_REF:0000033 MGI:5285147 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IBA
IEA		 (PMID:21401405)
GO_REF:0000033
GO_REF:0000107
(MGI:5285147|PMID:20940257)		 RGD
GO_Central
Ensembl		 PMID:20940257 PMID:21401405 GO_REF:0000033 GO_REF:0000107 MGI:5285147 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
IBA
ISS		 (PMID:20676705), (PMID:21401405)
GO_REF:0000033
(MGI:4950303|PMID:21367821), (MGI:5285147|PMID:20940257)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405 GO_REF:0000024 GO_REF:0000033 MGI:4950303 MGI:5285147 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Thrb thyroid hormone receptor beta IDA RGD PMID:15647824 RGD:1601663 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS		 (PMID:21547890)
GO_REF:0000024		 RGD
UniProt		 PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
G Zfp219 zinc finger protein 219 involved_in ISO (MGI:5285147|PMID:20940257) RGD PMID:20940257 MGI:5285147 NCBI chr15:24,695,831...24,710,039
Ensembl chr15:24,695,837...24,710,030 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    positive regulation of biological process 6651
      positive regulation of multicellular organismal process 1881
        positive regulation of cartilage development 33
          positive regulation of chondrocyte differentiation + 22
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            skeletal system development 575
              cartilage development 236
                regulation of cartilage development 75
                  positive regulation of cartilage development 33
                    positive regulation of chondrocyte differentiation + 22
paths to the root