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ONTOLOGY REPORT - ANNOTATIONS

Term:salivary gland morphogenesis
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Accession:GO:0007435 term browser browse the term
Definition:The process in which the anatomical structures of the salivary gland are generated and organized.


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salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO MGI:1857654 (PMID:11731698) RGD PMID:11731698 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Ctnnd1 catenin delta 1 acts_upstream_of_or_within ISO MGI:3617486 (PMID:16399075) RGD PMID:16399075 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Egfr epidermal growth factor receptor acts_upstream_of_or_within ISO MGI:1935113 (PMID:10521784) RGD PMID:10521784 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:15654336) RGD PMID:15654336 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:12421715) RGD PMID:12421715 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856158 (PMID:11731698)		 Ensembl
RGD		 PMID:11731698 GO_REF:0000107 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO MGI:5427084 (PMID:24388753) RGD PMID:24388753 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18080134)		 AgBase
RGD		 PMID:18080134 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18080134)		 AgBase
RGD		 PMID:18080134 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18080134)		 AgBase
RGD		 PMID:18080134 GO_REF:0000024 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 acts_upstream_of_or_within ISO MGI:3830633 (PMID:16289463) RGD PMID:16289463 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
branch elongation involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:15972105) RGD PMID:15972105 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809|MGI:2153811 (PMID:15972105) RGD PMID:15972105 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
branching involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO MGI:1857654 (PMID:11731698) RGD PMID:11731698 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Dag1 dystroglycan 1 acts_upstream_of_or_within ISO (PMID:11798066) RGD PMID:11798066 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 acts_upstream_of_or_within ISO MGI:1924661 (PMID:26371508) RGD PMID:26371508 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062 		JBrowse link
G Esrp2 epithelial splicing regulatory protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1917326 (PMID:26371508)		 Ensembl
RGD		 PMID:26371508 GO_REF:0000107 NCBI chr19:34,034,559...34,041,726
Ensembl chr19:34,034,559...34,041,726 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:95523 (PMID:15972105), (PMID:18559345) RGD PMID:15972105 PMID:18559345 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf7 fibroblast growth factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18559345)		 Ensembl
RGD		 PMID:18559345 GO_REF:0000107 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:2686826|MGI:98297 (PMID:15042696), (PMID:15063181) RGD PMID:15042696 PMID:15063181 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:12421715), (PMID:18559345) RGD PMID:12421715 PMID:18559345 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153814 (PMID:11731698) RGD PMID:11731698 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:11275690) RGD PMID:11275690 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lama1 laminin subunit alpha 1 acts_upstream_of_or_within ISO (PMID:11798066) RGD PMID:11798066 NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478 		JBrowse link
G Lama5 laminin subunit alpha 5 acts_upstream_of_or_within ISO (PMID:14568553) RGD PMID:14568553 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (PMID:18559345) RGD PMID:18559345 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857796|MGI:99604 (PMID:15042696)		 Ensembl
RGD		 PMID:15042696 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tgm2 transglutaminase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15970210)		 Ensembl
RGD		 PMID:15970210 GO_REF:0000107 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
dichotomous subdivision of terminal units involved in salivary gland branching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:107558 (PMID:17626059) RGD PMID:17626059 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Plxna1 plexin A1 acts_upstream_of_or_within ISO (PMID:17626059) RGD PMID:17626059 NCBI chr 4:121,737,934...121,782,901
Ensembl chr 4:121,737,945...122,024,196 		JBrowse link
G Plxnd1 plexin D1 acts_upstream_of_or_within ISO (PMID:17626059) RGD PMID:17626059 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Sema3a semaphorin 3A acts_upstream_of_or_within ISO MGI:106206 (PMID:17626059) RGD PMID:17626059 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sema3c semaphorin 3C acts_upstream_of_or_within ISO (PMID:17626059) RGD PMID:17626059 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
epithelial cell proliferation involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:95523 (PMID:15972105) RGD PMID:15972105 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809|MGI:2153811 (PMID:15972105) RGD PMID:15972105 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:11275690) RGD PMID:11275690 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nkx3-1 NK3 homeobox 1 acts_upstream_of_or_within ISO MGI:1928654 (PMID:10906459) RGD PMID:10906459 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Pdgfb platelet derived growth factor subunit B acts_upstream_of_or_within ISO (PMID:18559345) RGD PMID:18559345 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15042696)		 Ensembl
RGD		 PMID:15042696 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:11241200) RGD PMID:11241200 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
regulation of branching involved in salivary gland morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd7 BTB domain containing 7 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:20671187)		 GO_Central
RGD		 PMID:20671187 GO_REF:0000033 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:18816447) RGD PMID:18816447 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (PMID:20671187) RGD PMID:20671187 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:11241200) RGD PMID:11241200 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:18559345)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18559345 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntn4 netrin 4 acts_upstream_of_or_within ISO (PMID:17588941) RGD PMID:17588941 NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390 		JBrowse link
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO (PMID:18559345) RGD PMID:18559345 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf7 fibroblast growth factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18559345)		 Ensembl
RGD		 PMID:18559345 GO_REF:0000107 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO (PMID:18559345) RGD PMID:18559345 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14517989)
GO_REF:0000107		 RGD
Ensembl		 PMID:14517989 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:14517989) RGD PMID:14517989 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
salivary gland cavitation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh1 cadherin 1 acts_upstream_of_or_within ISO (PMID:18816447) RGD PMID:18816447 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Eda ectodysplasin-A acts_upstream_of_or_within ISO (PMID:12629675) RGD PMID:12629675 NCBI chr  X:65,078,454...65,480,172
Ensembl chr  X:65,078,673...65,480,172 		JBrowse link
G Edar ectodysplasin-A receptor acts_upstream_of_or_within ISO (PMID:12629675) RGD PMID:12629675 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Nfib nuclear factor I/B acts_upstream_of_or_within ISO MGI:3530139 (PMID:25403566) RGD PMID:25403566 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16332353)		 Ensembl
RGD		 PMID:16332353 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tgm2 transglutaminase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15970210)		 Ensembl
RGD		 PMID:15970210 GO_REF:0000107 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
submandibular salivary gland formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 IEP RGD PMID:18784978 RGD:5688282 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:11062007) RGD PMID:11062007 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    developmental process 7105
      anatomical structure morphogenesis 3005
        animal organ morphogenesis 1170
          gland morphogenesis 170
            salivary gland morphogenesis 41
              adult salivary gland morphogenesis 0
              branching involved in salivary gland morphogenesis + 28
              epithelial cell proliferation involved in salivary gland morphogenesis 7
              larval salivary gland morphogenesis 0
              positive regulation of salivary gland formation by mesenchymal-epithelial signaling 0
              salivary gland cavitation + 6
              salivary gland histolysis 0
              submandibular salivary gland formation 2
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7105
      anatomical structure development 6607
        multicellular organism development 5324
          system development 4606
            exocrine system development 63
              salivary gland development 48
                salivary gland morphogenesis 41
                  adult salivary gland morphogenesis 0
                  branching involved in salivary gland morphogenesis + 28
                  epithelial cell proliferation involved in salivary gland morphogenesis 7
                  larval salivary gland morphogenesis 0
                  positive regulation of salivary gland formation by mesenchymal-epithelial signaling 0
                  salivary gland cavitation + 6
                  salivary gland histolysis 0
                  submandibular salivary gland formation 2
paths to the root