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ONTOLOGY REPORT - ANNOTATIONS

Term:microtubule depolymerization
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Accession:GO:0007019 term browser browse the term
Definition:The removal of tubulin heterodimers from one or both ends of a microtubule.
Synonyms:exact_synonym: microtubule disassembly;   microtubule shortening
 narrow_synonym: microtubule catastrophe;   microtubule depolymerization during nuclear congression


show annotations for term's descendants           Sort by:
microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway acts_upstream_of ISO (PMID:16525027) RGD PMID:16525027 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 IMP RGD PMID:20858895 RGD:7242937 NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953 		JBrowse link
G Bmerb1 bMERB domain containing 1 acts_upstream_of ISO (PMID:25099998) RGD PMID:25099998 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575 		JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:20858895 RGD:7242937 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of ISO MGI:3693618 (PMID:17113391) RGD PMID:17113391 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Htt huntingtin IMP RGD PMID:20858895 RGD:7242937 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650 		JBrowse link
G Kif14 kinesin family member 14 NOT|involved_in ISO (MGI:5607363|PMID:24949858) RGD PMID:24949858 MGI:5607363 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164 		JBrowse link
G Kif18a kinesin family member 18A involved_in ISO
IBA		 (PMID:17346968)
GO_REF:0000033		 RGD
GO_Central		 PMID:17346968 GO_REF:0000033 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kif18b kinesin family member 18B involved_in ISO
IBA		 (PMID:21820309)
GO_REF:0000033		 RGD
GO_Central		 PMID:21820309 GO_REF:0000033 NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850 		JBrowse link
G Kif24 kinesin family member 24 involved_in ISO
IBA		 (PMID:21620453)
GO_REF:0000033		 RGD
GO_Central		 PMID:21620453 GO_REF:0000033 NCBI chr 5:56,561,019...56,628,040
Ensembl chr 5:56,561,154...56,628,025 		JBrowse link
G Kif2b kinesin family member 2B involved_in ISO
ISS		 (PMID:19060894)
GO_REF:0000024		 RGD
UniProt		 PMID:19060894 GO_REF:0000024 NCBI chr10:76,394,160...76,396,379 JBrowse link
G Kif2c kinesin family member 2C involved_in IEA
ISO		 GO_REF:0000107
(PMID:19060894), (PMID:21820309)		 Ensembl
RGD		 PMID:19060894 PMID:21820309 GO_REF:0000107 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Nckap5 NCK-associated protein 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:37,369,948...38,283,257
Ensembl chr13:37,370,792...38,283,268 		JBrowse link
G Nckap5l NCK-associated protein 5-like involved_in ISO
IBA		 (PMID:26485573)
GO_REF:0000033		 RGD
GO_Central		 PMID:26485573 GO_REF:0000033 NCBI chr 7:130,553,683...130,591,886
Ensembl chr 7:130,555,368...130,591,857 		JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:20858895 RGD:7242937 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IDA RGD PMID:16982696 RGD:1642763 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric acts_upstream_of_or_within ISO (PMID:20176735) RGD PMID:20176735 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060 		JBrowse link
G Stmn1 stathmin 1 involved_in
acts_upstream_of_or_within		 TAS
IBA
ISO		 GO_REF:0000033
(PMID:9880330)
(PMID:10675326)		 GO_Central
RGD		 PMID:9880330 PMID:10675326 PMID:9788875 GO_REF:0000033, RGD:61528 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Stmn2 stathmin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Stmn3 stathmin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:168,416,810...168,424,946
Ensembl chr 3:168,416,810...168,425,056 		JBrowse link
G Stmn4 stathmin 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253 		JBrowse link
axonemal microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:99,800,185...99,826,546
Ensembl chr10:99,799,400...99,826,546 		JBrowse link
mitotic spindle microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccsap centriole, cilia and spindle-associated protein involved_in ISO (PMID:26562023) RGD PMID:26562023 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753 		JBrowse link
negative regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 GO_REF:0000107
(PMID:16525027)
GO_REF:0000033
(PMID:17192415)
(PMID:11166179)
GO_REF:0000024		 Ensembl
RGD
GO_Central
UniProt		 PMID:11166179 PMID:16525027 PMID:17192415 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO
ISS
IEA		 (PMID:11912491)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11912491 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Atxn7 ataxin 7 involved_in ISO (PMID:22100762) RGD PMID:22100762 NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106 		JBrowse link
G Bmerb1 bMERB domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25099998)		 GO_Central
RGD		 PMID:25099998 GO_REF:0000033 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575 		JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:8,746,176...8,806,067
Ensembl chr 3:8,746,176...8,806,072 		JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597 		JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISO
IEA
ISS		 (PMID:21215777)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21215777 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16061649)		 GO_Central
RGD		 PMID:16061649 GO_REF:0000033 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in
acts_upstream_of_or_within		 ISO UniProtKB:O75122 (PMID:15631994), (PMID:16866869)
(PMID:11290329)		 RGD PMID:11290329 PMID:15631994 PMID:16866869 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 acts_upstream_of_or_within IDA
ISO		 MGI:3693618 (PMID:11290329), (PMID:17113391) RGD PMID:11290329 PMID:17113391 PMID:11290329 RGD:68300 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 involved_in NAS PMID:11290329 UniProt PMID:11290329 RGD:68300 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023 		JBrowse link
G Diaph3 diaphanous-related formin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18458159)		 Ensembl
RGD		 PMID:18458159 GO_REF:0000107 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975 		JBrowse link
G Eml4 EMAP like 4 acts_upstream_of_or_within ISO (PMID:17196341) RGD PMID:17196341 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879 		JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5431268|PMID:22726441)		 UniProt
RGD		 PMID:22726441 GO_REF:0000024 MGI:5431268 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 involved_in ISO
ISS		 (PMID:12584248) RGD PMID:12584248 PMID:12584248 RGD:12790645 NCBI chr14:79,955,350...79,961,830
Ensembl chr14:79,950,555...79,961,438 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12584248)		 UniProt
RGD		 PMID:12584248 GO_REF:0000024 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881 		JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of_or_within ISO (PMID:12486003) RGD PMID:12486003 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hdgfl3 HDGF like 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3849122|PMID:19237540)		 UniProt
RGD		 PMID:19237540 GO_REF:0000024 MGI:3849122 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650 		JBrowse link
G Map1a microtubule-associated protein 1A IDA RGD PMID:11896150 RGD:71122 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map1b microtubule-associated protein 1B IDA RGD PMID:11896150 RGD:71122 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map2 microtubule-associated protein 2 involved_in IMP PMID:11029056 CAFA PMID:11029056 RGD:12793013 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map6d1 MAP6 domain containing 1 acts_upstream_of_or_within ISO (PMID:16837464) RGD PMID:16837464 NCBI chr11:80,734,148...80,740,377
Ensembl chr11:80,734,148...80,740,377 		JBrowse link
G Mid1 midline 1 acts_upstream_of_or_within ISO MGI:1915291 (PMID:15070402) RGD PMID:15070402 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1100537 (PMID:15070402)		 UniProt
RGD		 PMID:15070402 GO_REF:0000024 NCBI chr  X:12,060,993...12,063,318
Ensembl chr  X:12,060,883...12,065,774 		JBrowse link
G Nav3 neuron navigator 3 involved_in ISO (PMID:25678558) RGD PMID:25678558 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO (PMID:21703590) RGD PMID:21703590 NCBI chr20:13,337,983...13,443,665
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
G Spef1 sperm flagellar 1 involved_in ISO (MGI:5908342|PMID:16206169) RGD PMID:16206169 MGI:5908342 NCBI chr 3:118,390,659...118,396,842
Ensembl chr 3:118,390,575...118,394,531 		JBrowse link
G Stmn2 stathmin 2 involved_in ISO
IEA		 (PMID:18452648)
GO_REF:0000107		 RGD
Ensembl		 PMID:18452648 GO_REF:0000107 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO (PMID:12639963) RGD PMID:12639963 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:26414402) RGD PMID:26414402 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Trim54 tripartite motif-containing 54 acts_upstream_of_or_within ISO (PMID:10953002) RGD PMID:10953002 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:26323690) RGD PMID:26323690 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223 		JBrowse link
G Wdr47 WD repeat domain 47 acts_upstream_of_or_within ISO MGI:6102912 (PMID:29078390) RGD PMID:29078390 NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739 		JBrowse link
plus-end specific microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif19 kinesin family member 19 involved_in ISO (MGI:5460922|PMID:23168168) RGD PMID:23168168 MGI:5460922 NCBI chr10:99,800,185...99,826,546
Ensembl chr10:99,799,400...99,826,546 		JBrowse link
positive regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A IDA RGD PMID:18442977 RGD:7241017 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Katnb1 katanin regulatory subunit B1 involved_in ISO (PMID:10751153) RGD PMID:10751153 NCBI chr19:9,921,216...9,940,853
Ensembl chr19:9,921,219...9,940,650 		JBrowse link
G Spast spastin involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954 		JBrowse link
G Stmn2 stathmin 2 involved_in ISO
IEA		 (PMID:18452648)
GO_REF:0000107		 RGD
Ensembl		 PMID:18452648 GO_REF:0000107 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in IDA PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
regulation of microtubule depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map1a microtubule-associated protein 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map1b microtubule-associated protein 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map1s microtubule-associated protein 1S involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular component organization or biogenesis 6958
        cellular component organization 6699
          supramolecular fiber organization 874
            microtubule depolymerization 59
              astral microtubule depolymerization + 0
              cytoplasmic microtubule depolymerization + 1
              minus-end specific microtubule depolymerization 0
              mitotic spindle microtubule depolymerization 1
              negative regulation of microtubule depolymerization + 36
              plus-end specific microtubule depolymerization 1
              positive regulation of microtubule depolymerization 5
              regulation of microtubule depolymerization + 40
Path 2
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular component organization or biogenesis 6958
        cellular component organization 6699
          organelle organization 3689
            cytoskeleton organization 1530
              microtubule cytoskeleton organization 671
                microtubule polymerization or depolymerization 141
                  microtubule depolymerization 59
                    astral microtubule depolymerization + 0
                    cytoplasmic microtubule depolymerization + 1
                    minus-end specific microtubule depolymerization 0
                    mitotic spindle microtubule depolymerization 1
                    negative regulation of microtubule depolymerization + 36
                    plus-end specific microtubule depolymerization 1
                    positive regulation of microtubule depolymerization 5
                    regulation of microtubule depolymerization + 40
paths to the root