.
vulvar disease - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:vulvar disease
go back to main search page
Accession:DOID:2059 term browser browse the term
Definition:A female reproductive system disease that is located_in the vulva. (DO)
Synonyms:exact_synonym: vulvar diseases
 primary_id: MESH:D014845
 xref: NCI:C27631
For additional species annotation, visit the Alliance of Genome Resources.

 Loading Annotations... 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
bowenoid papulosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 ISO mRNA:increased expression:perianal skin (human) RGD PMID:20346172 RGD:152998971 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO mRNA:increased expression:perianal skin (human) RGD PMID:20346172 RGD:152998971 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
vulva cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 severity ISO associated with Papillomavirus Infections RGD PMID:22685591 RGD:38676500 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO RGD PMID:10027405 RGD:2293612 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Nos3 nitric oxide synthase 3 disease_progression ISO DNA:repeat:intron RGD PMID:15196865 RGD:2292078 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO associated with Papillomavirus Infections;DNA:polymorphisms: :HLA-DQB1*03032,DQB1*5(human) RGD PMID:12543794 RGD:2314696 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-CE15 RT1 class I, locus CE15 susceptibility ISO associated with Papillomavirus Infections;DNA:polymorphism: :HLA-A2 RGD PMID:12543794 RGD:2314696 NCBI chr20:3,269,135...3,283,819
Ensembl chr20:3,264,172...3,279,563
Ensembl chr20:3,264,172...3,279,563 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 susceptibility ISO associated with Papillomavirus Infections;DNA:polymorphism: :HLA-A2 RGD PMID:12543794 RGD:2314696 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO associated with Papillomavirus Infections;DNA:polymorphisms: :HLA-DRB1*11,DRB1*01,DRB1*13(human) RGD PMID:12543794 RGD:2314696 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
vulva squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc25a cell division cycle 25A ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdc25c cell division cycle 25C disease_progression ISO protein:increased expression:vulva RGD PMID:20500813 RGD:2729590 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Sfn stratifin ISO DNA, mRNA:hypermethylation, decreased expression:vulva RGD PMID:11896620 RGD:2299936 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
Vulvar Lichen Sclerosus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17300232 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:18076706 RGD:2293866 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18076706 RGD:2293866 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17300232 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Vulvar Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO protein:increased expression:vulva
associated with Papillomavirus Infections;protein:increased expression:vulva 		RGD PMID:16998595 PMID:18192968 RGD:2289682, RGD:2289673 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 ISO associated with Papillomavirus Infections;protein:increased expression:vulva RGD PMID:18192968 PMID:16998595 RGD:2289673, RGD:2289682
G Chek2 checkpoint kinase 2 ISO DNA:polymorphism:cds:252A>G RGD PMID:11875739 RGD:2298483 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase disease_progression ISO protein:decreased expression:vulva, squamous epithelial cell RGD PMID:16608079 RGD:2301231 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Mlh1 mutL homolog 1 ISO protein:increased expression:vulva RGD PMID:15870899 RGD:2293514 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 ISO protein:increased expression:vulva RGD PMID:15870899 RGD:2293514 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Tp53 tumor protein p53 ISO
IEP 		protein:increased expression:vulva RGD PMID:16033093 PMID:30514679 RGD:2290537, RGD:14995938 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 ISO mRNA, protein:splice variant, increased expression:vulva RGD PMID:11720444 RGD:2290590 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
Vulvar Vestibulitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta ISO RGD PMID:9015038 RGD:7394738 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:vagina RGD PMID:9015038 RGD:7394738 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
vulvovaginal candidiasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:23853597 RGD:39938863 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mbl2 mannose binding lectin 2 ISO DNA:SNP:cds: RGD PMID:17470593 RGD:8693700 NCBI chr 1:237,429,873...237,465,567 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19140
    disease of anatomical entity 18453
      reproductive system disease 3193
        female reproductive system disease 2191
          vulvar disease 28
            Pruritus Vulvae 0
            Trichomonas vaginalis trichomoniasis 0
            Vulvar Lichen Sclerosus 4
            Vulvar Neoplasms + 19
            Vulvodynia 0
            atrophic vulva 0
            bowenoid papulosis 2
            ulceration of vulva 0
            vulva fibroepithelial polyp 0
            vulvar dystrophy 0
            vulvitis + 5
Path 2
Term Annotations click to browse term
  disease 19140
    disease of anatomical entity 18453
      Urogenital Diseases 5402
        Female Urogenital Diseases and Pregnancy Complications 2678
          Female Urogenital Diseases 2194
            female reproductive system disease 2191
              vulvar disease 28
                Pruritus Vulvae 0
                Trichomonas vaginalis trichomoniasis 0
                Vulvar Lichen Sclerosus 4
                Vulvar Neoplasms + 19
                Vulvodynia 0
                atrophic vulva 0
                bowenoid papulosis 2
                ulceration of vulva 0
                vulva fibroepithelial polyp 0
                vulvar dystrophy 0
                vulvitis + 5
paths to the root