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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tricetin
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Accession:CHEBI:507499 term browser browse the term
Definition:Flavone hydroxylated at positions 3', 4', 5, 5' and 7.
Synonyms:exact_synonym: 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3',4',5,5',7-pentahydroxyflavone;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-7-3-8(17)14-9(18)5-12(22-13(14)4-7)6-1-10(19)15(21)11(20)2-6/h1-5,16-17,19-21H;   InChIKey=ARSRJFRKVXALTF-UHFFFAOYSA-N;   SMILES=Oc1cc(O)c2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1
 alt_id: CHEBI:44171;   CHEBI:9680
 xref: CAS:520-31-0;   DrugBank:DB08230;   KEGG:C10192;   KNApSAcK:C00013328;   LIPID_MAPS_instance:LMPK12110847
 xref_mesh: MESH:C469689
 xref: MetaCyc:CPD-12570;   PDBeChem:MYF;   PMID:12440738;   PMID:16730127;   PMID:19705844;   PMID:21067180;   PMID:23352409;   Reaxys:307745
 cyclic_relationship: is_conjugate_acid_of CHEBI:60045


show annotations for term's descendants           Sort by:
tricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ajap1 adherens junctions associated protein 1 increases expression ISO tricetin results in increased expression of AJAP1 mRNA CTD PMID:38654487 NCBI chr 5:163,907,846...164,021,004
Ensembl chr 5:163,907,847...164,020,317 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO tricetin results in increased expression of ANGPTL4 mRNA CTD PMID:38654487 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Angptl7 angiopoietin like 7 decreases expression ISO tricetin results in decreased expression of ANGPTL7 mRNA CTD PMID:38654487 NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO tricetin results in increased expression of ASNS mRNA CTD PMID:38654487 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO tricetin inhibits the reaction [Oxidopamine results in increased expression of BAX mRNA]; tricetin inhibits the reaction [Oxidopamine results in increased expression of BAX protein] CTD PMID:31176653 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO tricetin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 mRNA]; tricetin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein] CTD PMID:31176653 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO tricetin results in increased expression of BMP2 mRNA CTD PMID:38654487 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions
decreases expression		 ISO SB 203580 promotes the reaction [tricetin results in decreased expression of BMP6 protein]
tricetin results in decreased expression of BMP6 mRNA; tricetin results in decreased expression of BMP6 protein		 CTD PMID:38654487 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO tricetin inhibits the reaction [Oxidopamine results in increased expression of and results in increased activity of CASP3 protein] CTD PMID:31176653 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 decreases expression ISO tricetin results in decreased expression of CEMIP mRNA CTD PMID:38654487 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO tricetin results in increased expression of CHAC1 mRNA CTD PMID:38654487 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO tricetin results in decreased expression of CYP1A1 mRNA CTD PMID:38654487 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression ISO tricetin results in decreased expression of CYP24A1 mRNA CTD PMID:38654487 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO tricetin results in decreased expression of DIO2 mRNA CTD PMID:38654487 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Edn2 endothelin 2 decreases expression ISO tricetin results in decreased expression of EDN2 mRNA CTD PMID:38654487 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 increases expression ISO tricetin results in increased expression of ENTREP1 mRNA CTD PMID:38654487 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758 		JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO tricetin results in decreased expression of GASK1B mRNA CTD PMID:38654487 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477 		JBrowse link
G Gpc5 glypican 5 decreases expression ISO tricetin results in decreased expression of GPC5 mRNA CTD PMID:38654487 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282 		JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO tricetin results in increased expression of H2BC21 mRNA CTD PMID:38654487 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO tricetin results in increased expression of HMOX1 mRNA; tricetin results in increased expression of HMOX1 protein CTD PMID:31176653 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO tricetin results in increased expression of INPP5D mRNA CTD PMID:38654487 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Itga4 integrin subunit alpha 4 decreases expression ISO tricetin results in decreased expression of ITGA4 mRNA CTD PMID:38654487 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO tricetin results in increased expression of KEAP1 mRNA; tricetin results in increased expression of KEAP1 protein CTD PMID:31176653 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Krt13 keratin 13 decreases expression ISO tricetin results in decreased expression of KRT13 mRNA CTD PMID:38654487 NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084 		JBrowse link
G Krtap2-1 keratin associated protein 2-1 increases expression ISO tricetin results in increased expression of KRTAP2-1 mRNA CTD PMID:38654487 NCBI chr10:84,572,164...84,572,587
Ensembl chr10:84,572,164...84,572,556 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO tricetin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:31176653 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO tricetin results in decreased expression of MMP9 mRNA; tricetin results in decreased expression of MMP9 protein
tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]		 CTD PMID:27860196 PMID:28731287 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression		 ISO tricetin results in increased expression of and affects the localization of NFE2L2 protein
tricetin results in increased expression of NFE2L2 mRNA		 CTD PMID:31176653 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO tricetin results in decreased expression of NQO1 mRNA CTD PMID:31176653 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO tricetin results in decreased expression of NREP mRNA CTD PMID:38654487 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
multiple interactions		 ISO tricetin results in decreased activity of PARP1 protein
tricetin inhibits the reaction [Oxidopamine results in increased expression of PARP1 protein]		 CTD PMID:17884996 PMID:31176653 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Peg10 paternally expressed 10 decreases expression ISO tricetin results in decreased expression of PEG10 mRNA CTD PMID:38654487 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Plch2 phospholipase C, eta 2 increases expression ISO tricetin results in increased expression of PLCH2 mRNA CTD PMID:38654487 NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO tricetin results in increased expression of PMAIP1 mRNA CTD PMID:38654487 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO tricetin results in decreased expression of POLA1 mRNA CTD PMID:38654487 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Ppl periplakin decreases expression ISO tricetin results in decreased expression of PPL mRNA CTD PMID:38654487 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO tricetin results in decreased expression of PTGIS mRNA CTD PMID:38654487 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO tricetin results in increased expression of PTX3 mRNA CTD PMID:38654487 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Sema5a semaphorin 5A decreases expression ISO tricetin results in decreased expression of SEMA5A mRNA CTD PMID:38654487 NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084 		JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 increases expression ISO tricetin results in increased expression of SPRY4 mRNA CTD PMID:38654487 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO tricetin results in increased expression of TNFAIP3 mRNA CTD PMID:38654487 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO tricetin results in increased expression of TP53I3 mRNA CTD PMID:38654487 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Trib2 tribbles pseudokinase 2 increases expression ISO tricetin results in increased expression of TRIB2 mRNA CTD PMID:38654487 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
3',5'-di-O-methyltricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO tricin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] CTD PMID:16552572 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        biochemical role 19566
          metabolite 19533
            tricetin 44
              3',4',5'-O-trimethyltricetin 0
              3',5'-di-O-methyltricetin + 1
              3'-O-methyltricetin + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic heterocyclic compound 18881
                                  oxacycle 17917
                                    benzopyran 11984
                                      1-benzopyran 11737
                                        flavonoid 7229
                                          anthoxanthin 4587
                                            flavones 4587
                                              hydroxyflavone 4561
                                                pentahydroxyflavone 4360
                                                  tricetin 44
                                                    3',4',5'-O-trimethyltricetin 0
                                                    3',5'-di-O-methyltricetin + 1
                                                    3'-O-methyltricetin + 0
paths to the root