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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phosphane
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Accession:CHEBI:30278 term browser browse the term
Definition:The simplest phosphine, consisting of a single phosphorus atom with three hydrogens attached.
Synonyms:exact_synonym: phosphorus trihydride;   trihydridophosphorus
 related_synonym: Formula=H3P;   InChI=1S/H3P/h1H3;   InChIKey=XYFCBTPGUUZFHI-UHFFFAOYSA-N;   PH3;   Phosphorwasserstoff;   SMILES=[H]P([H])[H];   fosfano;   fosfina;   phosphine
 xref: CAS:7803-51-2;   FooDB:FDB013348;   Gmelin:287;   HMDB:HMDB0034790
 xref_mesh: MESH:C044646
 xref: MetaCyc:CPD-21528;   PMID:11841601;   PMID:12694741;   PMID:21894233;   PPDB:1456;   Pesticides:phosphine;   Reaxys:3600171;   Wikipedia:Phosphane
 cyclic_relationship: is_conjugate_acid_of CHEBI:29938;   is_conjugate_base_of CHEBI:30282


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phosphane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 increases expression EXP phosphine results in increased expression of ABCB10 mRNA CTD PMID:34427094 NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP phosphine results in increased expression of AGTR1 mRNA CTD PMID:34427094 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Aplnr apelin receptor decreases expression EXP phosphine results in decreased expression of APLNR mRNA CTD PMID:34427094 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Bmp6 bone morphogenetic protein 6 affects expression EXP phosphine affects the expression of BMP6 mRNA CTD PMID:34427094 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression EXP phosphine results in increased expression of BMPR1A mRNA CTD PMID:34427094 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cbl Cbl proto-oncogene affects expression EXP phosphine affects the expression of CBL mRNA CTD PMID:34427094 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP phosphine results in increased expression of CTGF mRNA CTD PMID:34427094 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ciao2b cytosolic iron-sulfur assembly component 2B increases expression EXP phosphine results in increased expression of CIAO2B mRNA CTD PMID:34427094 NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068 		JBrowse link
G Cp ceruloplasmin increases expression EXP phosphine results in increased expression of CP mRNA CTD PMID:34427094 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression EXP phosphine results in increased expression of EPAS1 mRNA CTD PMID:34427094 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epor erythropoietin receptor affects expression EXP phosphine affects the expression of EPOR mRNA CTD PMID:34427094 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression EXP phosphine results in decreased expression of GRB2 mRNA CTD PMID:34427094 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP phosphine results in increased expression of HMOX1 mRNA CTD PMID:34427094 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone increases expression EXP phosphine results in increased expression of HSCB mRNA CTD PMID:34427094 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909 		JBrowse link
G Ireb2 iron responsive element binding protein 2 affects expression EXP phosphine affects the expression of IREB2 mRNA CTD PMID:34427094 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Jak2 Janus kinase 2 decreases expression EXP phosphine results in decreased expression of JAK2 mRNA CTD PMID:34427094 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP phosphine results in increased expression of JUN mRNA CTD PMID:34427094 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Lyrm4 LYR motif containing 4 increases expression EXP phosphine results in increased expression of LYRM4 mRNA CTD PMID:34427094 NCBI chr17:28,746,457...28,861,849
Ensembl chr17:28,746,469...28,861,750 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP phosphine results in increased expression of NOS3 mRNA CTD PMID:34427094 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 affects expression EXP phosphine affects the expression of PCBP1 mRNA CTD PMID:34427094 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 affects expression EXP phosphine affects the expression of PDK1 mRNA CTD PMID:34427094 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP phosphine results in increased expression of SERPINE1 mRNA CTD PMID:34427094 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 increases expression EXP phosphine results in increased expression of SLC25A37 mRNA CTD PMID:34427094 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Smad4 SMAD family member 4 increases expression EXP phosphine results in increased expression of SMAD4 mRNA CTD PMID:34427094 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP phosphine results in increased expression of SOCS1 mRNA CTD PMID:34427094 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP phosphine results in increased expression of SOCS3 mRNA CTD PMID:34427094 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression EXP phosphine results in increased expression of SRC mRNA CTD PMID:34427094 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A decreases expression EXP phosphine results in decreased expression of STAT5 mRNA CTD PMID:34427094 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Tfrc transferrin receptor increases expression EXP phosphine results in increased expression of TFRC mRNA CTD PMID:34427094 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 decreases expression EXP phosphine results in decreased expression of TWSG1 mRNA CTD PMID:34427094 NCBI chr 9:105,533,116...105,567,460
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
TCEP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase multiple interactions
affects folding
increases reduction		 EXP
ISO		 tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of Arsenic]
tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of arsenite]
tris(2-carboxyethyl)phosphine affects the folding of AS3MT protein
tris(2-carboxyethyl)phosphine results in increased reduction of AS3MT protein		 CTD PMID:15025511 PMID:22955273 PMID:25349987 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Crygd crystallin, gamma D decreases oxidation ISO [tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein] which results in decreased oxidation of CRYGD mRNA mutant form; tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein CTD PMID:30242128 NCBI chr 9:66,442,057...66,443,668
Ensembl chr 9:66,442,054...66,444,067 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO tris(2-carboxyethyl)phosphine inhibits the reaction [Cadmium promotes the reaction [MTF1 protein binds to MTF1 protein]]; tris(2-carboxyethyl)phosphine inhibits the reaction [Copper promotes the reaction [MTF1 protein binds to MTF1 protein]] CTD PMID:22057392 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136 		JBrowse link
G Neil1 nei-like DNA glycosylase 1 multiple interactions ISO [tris(2-carboxyethyl)phosphine co-treated with Edetic Acid] inhibits the reaction [Copper results in decreased activity of NEIL1 protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [Hydrogen Peroxide results in decreased activity of NEIL1 protein] CTD PMID:20622253 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 decreases activity EXP tris(2-carboxyethyl)phosphine results in decreased activity of SLC34A1 protein CTD PMID:10926679 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [sodium chromate(VI) results in increased oxidation of TXN protein] CTD PMID:19135121 PMID:19703554 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txn2 thioredoxin 2 multiple interactions ISO tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN2 protein] CTD PMID:19703554 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      chemical role 19489
        catalyst 8302
          phosphine 37
            phosphane 37
              phosphanediyl group 0
              phosphanetriyl group 0
              phosphanyl group 0
              phosphanylidene group 0
              phosphine derivative + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    main group molecular entity 19806
                      s-block molecular entity 19641
                        hydrogen molecular entity 19622
                          hydrides 19150
                            inorganic hydride 18152
                              pnictogen hydride 18164
                                phosphorus hydride 37
                                  phosphanes 37
                                    phosphane 37
                                      phosphanediyl group 0
                                      phosphanetriyl group 0
                                      phosphanyl group 0
                                      phosphanylidene group 0
                                      phosphine derivative + 7
paths to the root