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G |
Abcb10 |
ATP binding cassette subfamily B member 10 |
increases expression |
EXP |
phosphine results in increased expression of ABCB10 mRNA |
CTD |
PMID:34427094 |
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NCBI chr19:68,850,108...68,881,689
Ensembl chr19:51,952,681...51,982,753
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G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression |
EXP |
phosphine results in increased expression of AGTR1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,174,429...34,226,946
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G |
Aplnr |
apelin receptor |
decreases expression |
EXP |
phosphine results in decreased expression of APLNR mRNA |
CTD |
PMID:34427094 |
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NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:70,217,385...70,221,050
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G |
Bmp6 |
bone morphogenetic protein 6 |
affects expression |
EXP |
phosphine affects the expression of BMP6 mRNA |
CTD |
PMID:34427094 |
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NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365
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G |
Bmpr1a |
bone morphogenetic protein receptor type 1A |
increases expression |
EXP |
phosphine results in increased expression of BMPR1A mRNA |
CTD |
PMID:34427094 |
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NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,736,630...9,780,616
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G |
Cbl |
Cbl proto-oncogene |
affects expression |
EXP |
phosphine affects the expression of CBL mRNA |
CTD |
PMID:34427094 |
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NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
phosphine results in increased expression of CTGF mRNA |
CTD |
PMID:34427094 |
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NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
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G |
Ciao2b |
cytosolic iron-sulfur assembly component 2B |
increases expression |
EXP |
phosphine results in increased expression of CIAO2B mRNA |
CTD |
PMID:34427094 |
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NCBI chr19:344,194...346,068
Ensembl chr19:344,203...346,068
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G |
Cp |
ceruloplasmin |
increases expression |
EXP |
phosphine results in increased expression of CP mRNA |
CTD |
PMID:34427094 |
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NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:102,439,624...102,498,075
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
EXP |
phosphine results in increased expression of EPAS1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228
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G |
Epor |
erythropoietin receptor |
affects expression |
EXP |
phosphine affects the expression of EPOR mRNA |
CTD |
PMID:34427094 |
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NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:20,489,678...20,494,257
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G |
Grb2 |
growth factor receptor bound protein 2 |
decreases expression |
EXP |
phosphine results in decreased expression of GRB2 mRNA |
CTD |
PMID:34427094 |
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NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309
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G |
Hmox1 |
heme oxygenase 1 |
increases expression |
EXP |
phosphine results in increased expression of HMOX1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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G |
Hscb |
HscB mitochondrial iron-sulfur cluster co-chaperone |
increases expression |
EXP |
phosphine results in increased expression of HSCB mRNA |
CTD |
PMID:34427094 |
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NCBI chr12:51,481,318...51,491,689
Ensembl chr12:45,821,555...45,831,909
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G |
Ireb2 |
iron responsive element binding protein 2 |
affects expression |
EXP |
phosphine affects the expression of IREB2 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611
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G |
Jak2 |
Janus kinase 2 |
decreases expression |
EXP |
phosphine results in decreased expression of JAK2 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
phosphine results in increased expression of JUN mRNA |
CTD |
PMID:34427094 |
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NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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G |
Lyrm4 |
LYR motif containing 4 |
increases expression |
EXP |
phosphine results in increased expression of LYRM4 mRNA |
CTD |
PMID:34427094 |
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NCBI chr17:28,951,912...29,067,300
Ensembl chr17:28,746,469...28,861,750
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G |
Nos3 |
nitric oxide synthase 3 |
increases expression |
EXP |
phosphine results in increased expression of NOS3 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
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G |
Pcbp1 |
poly(rC) binding protein 1 |
affects expression |
EXP |
phosphine affects the expression of PCBP1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:118,972,661...118,976,500
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
affects expression |
EXP |
phosphine affects the expression of PDK1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038
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G |
Serpine1 |
serpin family E member 1 |
increases expression |
EXP |
phosphine results in increased expression of SERPINE1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
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G |
Slc25a37 |
solute carrier family 25 member 37 |
increases expression |
EXP |
phosphine results in increased expression of SLC25A37 mRNA |
CTD |
PMID:34427094 |
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NCBI chr15:50,944,085...50,986,506
Ensembl chr15:44,536,727...44,577,199
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G |
Smad4 |
SMAD family member 4 |
increases expression |
EXP |
phosphine results in increased expression of SMAD4 mRNA |
CTD |
PMID:34427094 |
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NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438
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G |
Socs1 |
suppressor of cytokine signaling 1 |
increases expression |
EXP |
phosphine results in increased expression of SOCS1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383
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G |
Socs3 |
suppressor of cytokine signaling 3 |
increases expression |
EXP |
phosphine results in increased expression of SOCS3 mRNA |
CTD |
PMID:34427094 |
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NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
increases expression |
EXP |
phosphine results in increased expression of SRC mRNA |
CTD |
PMID:34427094 |
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NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
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G |
Stat5a |
signal transducer and activator of transcription 5A |
decreases expression |
EXP |
phosphine results in decreased expression of STAT5 mRNA |
CTD |
PMID:34427094 |
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NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
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G |
Tfrc |
transferrin receptor |
increases expression |
EXP |
phosphine results in increased expression of TFRC mRNA |
CTD |
PMID:34427094 |
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NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
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G |
Twsg1 |
twisted gastrulation BMP signaling modulator 1 |
decreases expression |
EXP |
phosphine results in decreased expression of TWSG1 mRNA |
CTD |
PMID:34427094 |
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NCBI chr 9:112,979,972...113,014,315
Ensembl chr 9:105,533,136...105,567,479
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G |
As3mt |
arsenite methyltransferase |
multiple interactions affects folding increases reduction |
EXP ISO |
tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of Arsenic] tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of arsenite] tris(2-carboxyethyl)phosphine affects the folding of AS3MT protein tris(2-carboxyethyl)phosphine results in increased reduction of AS3MT protein |
CTD |
PMID:15025511 PMID:22955273 PMID:25349987 |
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NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
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G |
Crygd |
crystallin, gamma D |
decreases oxidation |
ISO |
[tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein] which results in decreased oxidation of CRYGD mRNA mutant form; tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein |
CTD |
PMID:30242128 |
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NCBI chr 9:66,442,057...66,443,668
Ensembl chr 9:66,442,054...66,444,067
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G |
Mtf1 |
metal-regulatory transcription factor 1 |
multiple interactions |
ISO |
tris(2-carboxyethyl)phosphine inhibits the reaction [Cadmium promotes the reaction [MTF1 protein binds to MTF1 protein]]; tris(2-carboxyethyl)phosphine inhibits the reaction [Copper promotes the reaction [MTF1 protein binds to MTF1 protein]] |
CTD |
PMID:22057392 |
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NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:137,062,376...137,107,136
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G |
Neil1 |
nei-like DNA glycosylase 1 |
multiple interactions |
ISO |
[tris(2-carboxyethyl)phosphine co-treated with Edetic Acid] inhibits the reaction [Copper results in decreased activity of NEIL1 protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [Hydrogen Peroxide results in decreased activity of NEIL1 protein] |
CTD |
PMID:20622253 |
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NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258
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G |
Slc34a1 |
solute carrier family 34 member 1 |
decreases activity |
EXP |
tris(2-carboxyethyl)phosphine results in decreased activity of SLC34A1 protein |
CTD |
PMID:10926679 |
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NCBI chr17:9,224,010...9,238,983
Ensembl chr17:9,218,876...9,233,852
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [sodium chromate(VI) results in increased oxidation of TXN protein] |
CTD |
PMID:19135121 PMID:19703554 |
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NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629
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G |
Txn2 |
thioredoxin 2 |
multiple interactions |
ISO |
tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN2 protein] |
CTD |
PMID:19703554 |
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NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:109,496,761...109,510,359
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