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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: As3mt
Name: arsenite methyltransferase
Acc ID: CHEBI:63213
Term: TCEP
Definition: A tertiary phosphine in which phosphane is substituted with three 2-carboxyethyl groups. It is a commonly used reducing agent.
Chemical ID: MESH:C080938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
As3mtmultiple interactionsEXP 6480464CTDtris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of Arsenic]PMID:15025511
As3mtaffects foldingISORGD:13506976480464CTDtris(2-carboxyethyl)phosphine affects the folding of AS3MT proteinPMID:22955273
As3mtincreases reductionISORGD:13506976480464CTDtris(2-carboxyethyl)phosphine results in increased reduction of AS3MT proteinPMID:25349987
As3mtmultiple interactionsISORGD:13506976480464CTDtris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of arsenite]PMID:22955273 PMID:25349987
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