CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: malathion
Accession: CHEBI:6651
browse the term
Definition: A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Synonyms: exact_synonym: rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
related_synonym: Karbofos; Maldison; O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl); O,O-dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate; O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate; O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl; O,O-dimethyldithiophosphate diethylmercaptosuccinate; [(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester; carbophos; diethyl ((dimethoxyphosphinothioyl)thio)butanedioate; diethyl (dimethoxyphosphinothioylthio)succinate; diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate; mercaptothion
xref: Beilstein:1804525; CAS:121-75-5; DrugBank:DB00772; Drug_Central:1626; KEGG:C07497; KEGG:D00534
xref_mesh: MESH:D008294
xref: PMID:16083681; PMID:19399610; PMID:28950791; PMID:29235025; PMID:29792547; PMID:29852369; Reaxys:1804525; Wikipedia:Malathion
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1110032F04Rik
RIKEN cDNA 1110032F04 gene
decreases expression
ISO
Malathion results in decreased expression of C3ORF80 mRNA
CTD
PMID:37047231
NCBI chr 3:68,776,684...68,779,496
Ensembl chr 3:68,776,919...68,779,496
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1700024G13Rik
RIKEN cDNA 1700024G13 gene
decreases expression
ISO
Malathion results in decreased expression of C10ORF53 mRNA
CTD
PMID:37047231
NCBI chr14:32,098,459...32,110,330
Ensembl chr14:32,098,025...32,110,348
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1700031M16Rik
RIKEN cDNA 1700031M16 gene
decreases expression
ISO
Malathion results in decreased expression of C12ORF54 mRNA
CTD
PMID:37047231
NCBI chr15:98,296,326...98,314,016
Ensembl chr15:98,296,300...98,314,149 Ensembl chr15:98,296,300...98,314,149
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A830018L16Rik
RIKEN cDNA A830018L16 gene
decreases expression
ISO
Malathion results in decreased expression of C8ORF34 mRNA
CTD
PMID:37047231
NCBI chr 1:11,484,121...12,046,126
Ensembl chr 1:11,484,329...12,046,125
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AA467197
expressed sequence AA467197
increases expression
ISO
Malathion results in increased expression of C15ORF48 mRNA
CTD
PMID:37047231
NCBI chr 2:122,479,807...122,482,996
Ensembl chr 2:122,478,906...122,483,111
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Acbd5
acyl-Coenzyme A binding domain containing 5
increases expression
ISO
Malathion results in increased expression of ACBD5 mRNA
CTD
PMID:37047231
NCBI chr 2:22,958,189...23,004,525
Ensembl chr 2:22,958,179...23,005,570
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Ache
acetylcholinesterase
multiple interactions decreases activity
ISO EXP
[Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein] [Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; Taurine inhibits the reaction [Malathion results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]
CTD
PMID:2380476 PMID:4859365 PMID:14713564 PMID:18617161 PMID:19429256 PMID:19784758 PMID:21628957 PMID:21723318 PMID:21983245 PMID:23774768 PMID:28987951 PMID:30625376 More...
NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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Acot6
acyl-CoA thioesterase 6
decreases expression
ISO
Malathion results in decreased expression of ACOT6 mRNA
CTD
PMID:37047231
NCBI chr12:84,147,538...84,158,128
Ensembl chr12:84,147,428...84,158,123
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Acsm1
acyl-CoA synthetase medium-chain family member 1
decreases expression
EXP
Malathion results in decreased expression of ACSM1 mRNA
CTD
PMID:17311802
NCBI chr 7:119,217,035...119,261,738
Ensembl chr 7:119,206,249...119,261,738
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Adam11
a disintegrin and metallopeptidase domain 11
increases methylation
ISO
Malathion results in increased methylation of ADAM11 promoter
CTD
PMID:37047231
NCBI chr11:102,652,261...102,671,089
Ensembl chr11:102,652,265...102,671,088
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Adam32
a disintegrin and metallopeptidase domain 32
decreases expression
ISO
Malathion results in decreased expression of ADAM32 mRNA
CTD
PMID:37047231
NCBI chr 8:25,326,159...25,438,933
Ensembl chr 8:25,326,156...25,438,820
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Adamts12
ADAM metallopeptidase with thrombospondin type 1 motif 12
decreases expression
ISO
Malathion results in decreased expression of ADAMTS12 mRNA
CTD
PMID:37047231
NCBI chr15:11,064,781...11,349,321
Ensembl chr15:11,064,876...11,349,317
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Adamts20
ADAM metallopeptidase with thrombospondin type 1 motif 20
decreases expression
ISO
Malathion results in decreased expression of ADAMTS20 mRNA
CTD
PMID:37047231
NCBI chr15:94,166,177...94,329,966
Ensembl chr15:94,168,044...94,363,299
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Adamts6
ADAM metallopeptidase with thrombospondin type 1 motif 6
increases expression
ISO
Malathion results in increased expression of ADAMTS6 mRNA
CTD
PMID:37047231
NCBI chr13:104,423,026...104,633,203
Ensembl chr13:104,424,343...104,633,203
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Add3
adducin 3
increases expression
ISO
Malathion results in increased expression of ADD3 mRNA
CTD
PMID:19784758
NCBI chr19:53,128,874...53,235,518
Ensembl chr19:53,128,874...53,235,830
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Adm
adrenomedullin
increases expression
ISO
Malathion results in increased expression of ADM mRNA
CTD
PMID:37047231
NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
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Adra2a
adrenergic receptor, alpha 2a
increases expression
ISO
Malathion results in increased expression of ADRA2A mRNA
CTD
PMID:37047231
NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413
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Aff1
AF4/FMR2 family, member 1
increases expression
ISO
Malathion results in increased expression of AFF1 mRNA mutant form
CTD
PMID:28624474
NCBI chr 5:103,840,307...104,003,188
Ensembl chr 5:103,840,240...104,003,188
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Ahr
aryl-hydrocarbon receptor
multiple interactions
ISO
[prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein
CTD
PMID:25684042
NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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Akr1c20
aldo-keto reductase family 1, member C20
increases expression
ISO
Malathion results in increased expression of AKR1C1 mRNA
CTD
PMID:16079077 PMID:18214805
NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344
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Akr1c21
aldo-keto reductase family 1, member C21
increases expression
ISO
Malathion results in increased expression of AKR1C2 mRNA
CTD
PMID:16079077
NCBI chr13:4,624,074...4,636,542
Ensembl chr13:4,624,074...4,636,540
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Akr1e1
aldo-keto reductase family 1, member E1
decreases expression
ISO
Malathion results in decreased expression of AKR1E2 mRNA
CTD
PMID:37047231
NCBI chr13:4,641,122...4,659,163
Ensembl chr13:4,640,749...4,659,173
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Alkal2
ALK and LTK ligand 2
increases expression
ISO
Malathion results in increased expression of ALKAL2 mRNA
CTD
PMID:37047231
NCBI chr12:30,934,323...30,943,855
Ensembl chr12:30,934,321...30,943,853
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Amot
angiomotin
decreases expression
ISO
Malathion results in decreased expression of AMOT mRNA
CTD
PMID:37047231
NCBI chr X:144,229,420...144,288,145
Ensembl chr X:144,229,421...144,288,177
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Angptl2
angiopoietin-like 2
decreases expression
ISO
Malathion results in decreased expression of ANGPTL2 mRNA
CTD
PMID:37047231
NCBI chr 2:33,105,963...33,137,737
Ensembl chr 2:33,106,081...33,137,729
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Angptl4
angiopoietin-like 4
decreases methylation increases expression
ISO
Malathion results in decreased methylation of ANGPTL4 promoter Malathion results in increased expression of ANGPTL4 mRNA
CTD
PMID:37047231
NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
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Ank1
ankyrin 1, erythroid
decreases expression
ISO
Malathion results in decreased expression of ANK1 mRNA
CTD
PMID:37047231
NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513
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Ankrd55
ankyrin repeat domain 55
increases expression
ISO
Malathion results in increased expression of ANKRD55 mRNA
CTD
PMID:37047231
NCBI chr13:112,424,985...112,523,391
Ensembl chr13:112,424,985...112,520,536
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Aplf
aprataxin and PNKP like factor
decreases expression
ISO
Malathion results in decreased expression of APLF mRNA
CTD
PMID:37047231
NCBI chr 6:87,605,407...87,649,244
Ensembl chr 6:87,605,406...87,649,175
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Aqp12
aquaporin 12
decreases expression
ISO
Malathion results in decreased expression of AQP12A mRNA
CTD
PMID:37047231
NCBI chr 1:92,934,056...92,939,991
Ensembl chr 1:92,934,056...92,939,991
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Aqp9
aquaporin 9
increases expression
ISO
Malathion results in increased expression of AQP9 mRNA
CTD
PMID:37047231
NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
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Ar
androgen receptor
multiple interactions decreases expression
ISO
[terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein Malathion results in decreased expression of AR mRNA
CTD
PMID:23871939 PMID:36336997
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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Armc3
armadillo repeat containing 3
decreases expression
ISO
Malathion results in decreased expression of ARMC3 mRNA
CTD
PMID:37047231
NCBI chr 2:19,203,676...19,315,054
Ensembl chr 2:19,204,113...19,315,052
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Arnt2
aryl hydrocarbon receptor nuclear translocator 2
decreases expression
ISO
Malathion results in decreased expression of ARNT2 mRNA
CTD
PMID:37047231
NCBI chr 7:83,895,486...84,059,201
Ensembl chr 7:83,895,486...84,059,384
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Asic5
acid-sensing ion channel family member 5
increases expression
ISO
Malathion results in increased expression of ASIC5 mRNA
CTD
PMID:37047231
NCBI chr 3:81,889,600...81,928,540
Ensembl chr 3:81,889,597...81,928,540
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Atp2b3
ATPase, Ca++ transporting, plasma membrane 3
decreases expression
ISO
Malathion results in decreased expression of ATP2B3 mRNA
CTD
PMID:37047231
NCBI chr X:72,546,356...72,632,267
Ensembl chr X:72,546,692...72,614,611
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B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
decreases expression
ISO
Malathion results in decreased expression of B4GALT1 mRNA
CTD
PMID:32069766
NCBI chr 4:40,804,602...40,855,711
Ensembl chr 4:40,804,602...40,854,005
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B9d1
B9 protein domain 1
decreases expression
ISO
Malathion results in decreased expression of B9D1 mRNA
CTD
PMID:37047231
NCBI chr11:61,395,970...61,403,757
Ensembl chr11:61,395,970...61,403,757
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Bax
BCL2-associated X protein
decreases expression multiple interactions increases expression
ISO EXP
Malathion results in decreased expression of BAX mRNA Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein] Plant Extracts inhibits the reaction [Malathion results in increased expression of BAX protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of BAX protein] crocin inhibits the reaction [Malathion results in increased expression of BAX protein]
CTD
PMID:23774768 PMID:30769050 PMID:32120800 PMID:35274200
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Bche
butyrylcholinesterase
multiple interactions decreases activity increases activity
ISO
Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of BCHE protein] Malathion results in increased activity of BCHE protein
CTD
PMID:17364237 PMID:18617161 PMID:21983245 PMID:25180440
NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
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Bcl2
B cell leukemia/lymphoma 2
decreases expression multiple interactions increases expression
ISO EXP
Malathion results in decreased expression of BCL2 mRNA Malathion results in decreased expression of BCL2 protein Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein] Malathion results in increased expression of BCL2 mRNA Malathion results in increased expression of BCL2 protein
CTD
PMID:23774768 PMID:30673264 PMID:30769050 PMID:32120800
NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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Bdnf
brain derived neurotrophic factor
increases methylation decreases secretion
ISO
Malathion results in increased methylation of BDNF protein Malathion results in decreased secretion of BDNF protein
CTD
PMID:35292247
NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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Bmi1
Bmi1 polycomb ring finger oncogene
increases expression
ISO
Malathion results in increased expression of BMI1 mRNA
CTD
PMID:32069766
NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440
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Brd7
bromodomain containing 7
increases expression
EXP
Malathion results in increased expression of BRD7 mRNA
CTD
PMID:18214912
NCBI chr 8:89,056,522...89,089,249
Ensembl chr 8:89,057,667...89,088,822
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Bsnd
barttin CLCNK type accessory beta subunit
increases expression
ISO
Malathion results in increased expression of BSND mRNA
CTD
PMID:37047231
NCBI chr 4:106,340,653...106,349,440
Ensembl chr 4:106,340,653...106,349,480
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Btg1
BTG anti-proliferation factor 1
decreases expression
ISO
Malathion results in decreased expression of BTG1 mRNA
CTD
PMID:32069766
NCBI chr10:96,452,863...96,458,675
Ensembl chr10:96,452,868...96,458,671
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Bub1
BUB1, mitotic checkpoint serine/threonine kinase
decreases expression
ISO
Malathion results in decreased expression of BUB1 mRNA
CTD
PMID:16079077
NCBI chr 2:127,642,117...127,673,790
Ensembl chr 2:127,643,036...127,673,785
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C1ql2
complement component 1, q subcomponent-like 2
decreases expression
ISO
Malathion results in decreased expression of C1QL2 mRNA
CTD
PMID:37047231
NCBI chr 1:120,268,312...120,270,903
Ensembl chr 1:120,268,312...120,270,903
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Cabp7
calcium binding protein 7
decreases expression
ISO
Malathion results in decreased expression of CABP7 mRNA
CTD
PMID:37047231
NCBI chr11:4,686,892...4,697,179
Ensembl chr11:4,686,892...4,696,778
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Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
increases expression
ISO
Malathion results in increased expression of CACNA1C mRNA
CTD
PMID:37047231
NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions
ISO
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]
CTD
PMID:28385489
NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
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Camk2b
calcium/calmodulin-dependent protein kinase II, beta
multiple interactions
ISO
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]
CTD
PMID:28385489
NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
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Capn8
calpain 8
decreases expression
ISO
Malathion results in decreased expression of CAPN8 mRNA
CTD
PMID:37047231
NCBI chr 1:182,392,314...182,462,021
Ensembl chr 1:182,392,572...182,459,917
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Cartpt
CART prepropeptide
increases expression
ISO
Malathion results in increased expression of CARTPT mRNA
CTD
PMID:37047231
NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
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Casp3
caspase 3
increases activity multiple interactions increases expression increases cleavage
EXP ISO
Malathion results in increased activity of CASP3 protein [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP3 protein] Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein] Malathion results in increased activity of and results in increased cleavage of CASP3 protein; Metoclopramide inhibits the reaction [Malathion results in increased activity of and results in increased cleavage of CASP3 protein]
CTD
PMID:12505448 PMID:19815060 PMID:21628957 PMID:27941166 PMID:29027213 PMID:30769050 PMID:35274200 More...
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casp4
caspase 4, apoptosis-related cysteine peptidase
decreases expression
ISO
Malathion results in decreased expression of CASP4 mRNA
CTD
PMID:32069766
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
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Casp8
caspase 8
increases activity
EXP
Malathion results in increased activity of CASP8 protein
CTD
PMID:12505448
NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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Casp9
caspase 9
increases activity increases expression multiple interactions increases cleavage
EXP ISO
Malathion results in increased activity of CASP9 protein Malathion results in increased expression of CASP9 mRNA [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; crocin inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Levodopa inhibits the reaction [Malathion results in increased cleavage of CASP9 protein] Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
CTD
PMID:12505448 PMID:21628957 PMID:27941166 PMID:30769050 PMID:35274200
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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Cat
catalase
multiple interactions decreases activity increases activity decreases expression
ISO EXP
[Dimethoate co-treated with Malathion] results in increased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; Pentoxifylline inhibits the reaction [Malathion results in increased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein] [Malathion co-treated with 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide] results in increased activity of CAT protein; [Malathion co-treated with pralidoxime] results in increased activity of CAT protein; lavender oil inhibits the reaction [Malathion results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Malathion results in decreased activity of CAT protein]; Polyphenols inhibits the reaction [Malathion results in decreased activity of CAT protein] [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]
CTD
PMID:11834209 PMID:18655177 PMID:19429256 PMID:20194575 PMID:21628957 PMID:21723318 PMID:24810974 PMID:25180440 PMID:28987951 PMID:30409133 PMID:30673264 PMID:30769050 PMID:32120800 PMID:36336997 More...
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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Cbfb
core binding factor beta
increases expression
ISO
Malathion results in increased expression of CBFB mRNA
CTD
PMID:32069766
NCBI chr 8:105,897,306...105,944,621
Ensembl chr 8:105,897,306...105,944,621
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Ccdc126
coiled-coil domain containing 126
increases expression
ISO
Malathion results in increased expression of CCDC126 mRNA
CTD
PMID:37047231
NCBI chr 6:49,296,204...49,318,521
Ensembl chr 6:49,296,208...49,318,516
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Ccdc192
coiled-coil domain containing 192
increases expression
ISO
Malathion results in increased expression of CCDC192 mRNA
CTD
PMID:37047231
NCBI chr18:57,666,814...57,864,139
Ensembl chr18:57,666,852...57,864,137
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Cck
cholecystokinin
increases expression
ISO
Malathion results in increased expression of CCK mRNA
CTD
PMID:19784758
NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760
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Ccl1
C-C motif chemokine ligand 1
increases expression
ISO
Malathion results in increased expression of CCL1 mRNA
CTD
PMID:37047231
NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516
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Ccl19
C-C motif chemokine ligand 19
increases expression
ISO
Malathion results in increased expression of CCL19 mRNA
CTD
PMID:37047231
NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577
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Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
Malathion results in increased expression of CCL20 mRNA
CTD
PMID:37047231
NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
Malathion results in increased expression of CCL3 mRNA
CTD
PMID:37047231
NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
Malathion results in increased expression of CCL7 mRNA
CTD
PMID:37047231
NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
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Ccm2l
cerebral cavernous malformation 2-like
increases expression
ISO
Malathion results in increased expression of CCM2L mRNA
CTD
PMID:37047231
NCBI chr 2:152,907,857...152,923,655
Ensembl chr 2:152,907,875...152,923,655
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Ccna2
cyclin A2
decreases expression
ISO
Malathion results in decreased expression of CCNA2 protein
CTD
PMID:30769050
NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
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Ccnb1
cyclin B1
decreases expression
ISO
Malathion results in decreased expression of CCNB1 protein
CTD
PMID:30769050
NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
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Ccne1
cyclin E1
decreases expression
ISO
Malathion results in decreased expression of CCNE1 protein
CTD
PMID:30769050
NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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Ccser1
coiled-coil serine rich 1
increases expression
ISO
Malathion results in increased expression of CCSER1 mRNA
CTD
PMID:37047231
NCBI chr 6:61,156,942...62,359,847
Ensembl chr 6:61,157,308...62,359,849
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Cd14
CD14 antigen
decreases expression
ISO
Malathion results in decreased expression of CD14 mRNA
CTD
PMID:32069766
NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
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Cd274
CD274 antigen
increases expression
ISO
Malathion results in increased expression of CD274 mRNA
CTD
PMID:37047231
NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
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Cd36
CD36 molecule
increases expression
ISO
Malathion results in increased expression of CD36 mRNA
CTD
PMID:32069766
NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
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Cd5
CD5 antigen
decreases expression
ISO
Malathion results in decreased expression of CD5 mRNA
CTD
PMID:32069766
NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366
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Cd69
CD69 antigen
increases expression
ISO
Malathion results in increased expression of CD69 mRNA
CTD
PMID:37047231
NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
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Cdc20
cell division cycle 20
decreases expression
ISO
Malathion results in decreased expression of CDC20 mRNA
CTD
PMID:18214805
NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
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Cdk15
cyclin dependent kinase 15
increases expression
ISO
Malathion results in increased expression of CDK15 mRNA
CTD
PMID:37047231
NCBI chr 1:59,296,029...59,391,656
Ensembl chr 1:59,296,065...59,392,152
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Cdk2
cyclin dependent kinase 2
decreases expression increases expression
ISO
Malathion results in decreased expression of CDK2 protein Malathion results in increased expression of CDK2 mRNA
CTD
PMID:30769050 PMID:32069766
NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
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Cebpg
CCAAT/enhancer binding protein gamma
increases expression
ISO
Malathion results in increased expression of CEBPG mRNA
CTD
PMID:32069766
NCBI chr 7:34,745,847...34,755,991
Ensembl chr 7:34,745,847...34,755,998
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Cenpf
centromere protein F
decreases expression
ISO
Malathion results in decreased expression of CENPF mRNA
CTD
PMID:16079077
NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283
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Ces1d
carboxylesterase 1D
increases expression
EXP
Malathion results in increased expression of CES1 mRNA
CTD
PMID:17311802
NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
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Cfap157
cilia and flagella associated protein 157
decreases expression
ISO
Malathion results in decreased expression of CFAP157 mRNA
CTD
PMID:37047231
NCBI chr 2:32,667,425...32,674,417
Ensembl chr 2:32,667,393...32,674,440
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Cfap91
cilia and flagella associated protein 91
decreases expression
ISO
Malathion results in decreased expression of CFAP91 mRNA
CTD
PMID:37047231
NCBI chr16:38,118,116...38,162,222
Ensembl chr16:38,118,116...38,162,505
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Cfb
complement factor B
increases expression
ISO
Malathion results in increased expression of CFB mRNA
CTD
PMID:37047231
NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
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Ch25h
cholesterol 25-hydroxylase
increases expression
ISO
Malathion results in increased expression of CH25H mRNA
CTD
PMID:37047231
NCBI chr19:34,451,183...34,452,548
Ensembl chr19:34,451,178...34,452,564
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Cldn12
claudin 12
increases expression
ISO
Malathion results in increased expression of CLDN12 mRNA
CTD
PMID:37047231
NCBI chr 5:5,555,109...5,564,953
Ensembl chr 5:5,539,537...5,564,958
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Cldn22
claudin 22
decreases expression
ISO
Malathion results in decreased expression of CLDN22 mRNA
CTD
PMID:37047231
NCBI chr 8:48,277,501...48,278,511
Ensembl chr 8:48,277,517...48,278,511
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Cldn5
claudin 5
multiple interactions decreases expression
ISO
[Malathion co-treated with Lead] results in decreased expression of CLDN5 protein Malathion results in decreased expression of CLDN5 protein
CTD
PMID:20970449
NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012
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Cma1
chymase 1, mast cell
decreases expression
ISO
Malathion results in decreased expression of CMA1 mRNA
CTD
PMID:37047231
NCBI chr14:56,178,908...56,182,132
Ensembl chr14:56,178,908...56,182,132
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Cntn4
contactin 4
increases expression
ISO
Malathion results in increased expression of CNTN4 mRNA
CTD
PMID:37047231
NCBI chr 6:105,654,505...106,677,102
Ensembl chr 6:105,654,621...106,676,271
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Col1a2
collagen, type I, alpha 2
increases expression
ISO
Malathion results in increased expression of COL1A2 mRNA
CTD
PMID:32069766
NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
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Cpne9
copine family member IX
decreases expression
ISO
Malathion results in decreased expression of CPNE9 mRNA
CTD
PMID:37047231
NCBI chr 6:113,259,244...113,282,532
Ensembl chr 6:113,259,268...113,282,588
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Cpz
carboxypeptidase Z
decreases expression
ISO
Malathion results in decreased expression of CPZ mRNA
CTD
PMID:37047231
NCBI chr 5:35,659,562...35,682,970
Ensembl chr 5:35,659,562...35,683,042
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Crh
corticotropin releasing hormone
multiple interactions decreases expression
ISO
caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA]
CTD
PMID:20233601 PMID:25404496
NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
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Crisp3
cysteine-rich secretory protein 3
decreases expression
ISO
Malathion results in decreased expression of CRISP3 mRNA
CTD
PMID:37047231
NCBI chr17:40,532,668...40,553,179
Ensembl chr17:40,532,668...40,553,179
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Crispld2
cysteine-rich secretory protein LCCL domain containing 2
decreases expression
ISO
Malathion results in decreased expression of CRISPLD2 mRNA
CTD
PMID:19784758
NCBI chr 8:120,719,177...120,779,533
Ensembl chr 8:120,719,177...120,779,532
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Csf2
colony stimulating factor 2 (granulocyte-macrophage)
increases expression
ISO
Malathion results in increased expression of CSF2 protein Malathion results in increased expression of CSF2 mRNA
CTD
PMID:34778934 PMID:37047231
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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Csf3
colony stimulating factor 3 (granulocyte)
increases expression
ISO
Malathion results in increased expression of CSF3 mRNA
CTD
PMID:37047231
NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
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Ctsd
cathepsin D
increases expression
EXP
Malathion results in increased expression of CTSD protein
CTD
PMID:8812242
NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
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Cxcl11
chemokine (C-X-C motif) ligand 11
increases expression
ISO
Malathion results in increased expression of CXCL11 mRNA
CTD
PMID:37047231
NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344
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Cxcl15
C-X-C motif chemokine ligand 15
increases expression
ISO
Malathion results in increased expression of CXCL8 mRNA
CTD
PMID:37047231
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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Cybb
cytochrome b-245, beta polypeptide
multiple interactions increases expression
EXP
Plant Extracts inhibits the reaction [Malathion results in increased expression of CYBB protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of CYBB protein]
CTD
PMID:32120800
NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
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Cym
chymosin
decreases expression
ISO
Malathion results in decreased expression of CYMP mRNA
CTD
PMID:37047231
NCBI chr 3:107,118,611...107,129,048
Ensembl chr 3:107,118,609...107,129,048
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
multiple interactions decreases expression
EXP
lavender oil inhibits the reaction [Malathion results in decreased expression of CYP11A1 mRNA]
CTD
PMID:30409133
NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
multiple interactions
ISO
[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA
CTD
PMID:23954766
NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
affects metabolic processing increases expression
ISO
CYP1A2 protein affects the metabolism of Malathion Malathion results in increased expression of CYP1A2 mRNA
CTD
PMID:15557345 PMID:22310298
NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
increases expression
ISO
Malathion results in increased expression of CYP27B1 mRNA
CTD
PMID:37047231
NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875
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Cyp2a5
cytochrome P450, family 2, subfamily a, polypeptide 5
increases expression
ISO
Malathion results in increased expression of CYP2A6 mRNA
CTD
PMID:22310298
NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
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Cyp2b10
cytochrome P450, family 2, subfamily b, polypeptide 10
decreases activity affects metabolic processing increases expression multiple interactions
ISO
Malathion results in decreased activity of CYP2B6 protein CYP2B6 protein affects the metabolism of Malathion Malathion results in increased expression of CYP2B6 mRNA Malathion promotes the reaction [isomalathion results in increased expression of CYP2B6 mRNA]
CTD
PMID:15557345 PMID:22310298 PMID:24333466
NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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Cyp2c65
cytochrome P450, family 2, subfamily c, polypeptide 65
decreases activity multiple interactions
ISO
Malathion results in decreased activity of CYP2C9 protein Malathion inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Tolbutamide]
CTD
PMID:20183062 PMID:22634058
NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions decreases activity
ISO
Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone] Malathion results in decreased activity of CYP2E1 protein
CTD
PMID:22634058
NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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Cyp3a13
cytochrome P450, family 3, subfamily a, polypeptide 13
affects metabolic processing increases expression
ISO
CYP3A7 protein affects the metabolism of Malathion Malathion results in increased expression of CYP3A7 mRNA CYP3A5 protein affects the metabolism of Malathion Malathion results in increased expression of CYP3A5 mRNA
CTD
PMID:17110060 PMID:37047231
NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
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Cyp8b1
cytochrome P450, family 8, subfamily b, polypeptide 1
multiple interactions
ISO
[Insecticides results in increased abundance of Malathion] which affects the methylation of CYP8B1 gene
CTD
PMID:34516295
NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
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Dcn
decorin
increases expression
ISO
Malathion results in increased expression of DCN mRNA
CTD
PMID:37047231
NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
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Ddc
dopa decarboxylase
affects binding increases expression
ISO
Malathion binds to [DDC protein binds to Pyridoxal Phosphate]; Malathion binds to DDC protein Malathion results in increased expression of DDC mRNA
CTD
PMID:35151785 PMID:37047231
NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
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Ddr1
discoidin domain receptor family, member 1
decreases expression
ISO
Malathion results in decreased expression of DDR1 mRNA
CTD
PMID:37047231
NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
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Ddx11
DEAD/H box helicase 11
increases expression
ISO
Malathion results in increased expression of DDX11 mRNA
CTD
PMID:32069766
NCBI chr17:66,430,508...66,459,169
Ensembl chr17:66,430,515...66,459,169
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Dio1
deiodinase, iodothyronine, type I
decreases expression
ISO
Malathion results in decreased expression of DIO1 mRNA
CTD
PMID:37047231
NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
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Disc1
disrupted in schizophrenia 1
increases expression
ISO
Malathion results in increased expression of DISC1 mRNA
CTD
PMID:37047231
NCBI chr 8:125,773,928...125,991,882
Ensembl chr 8:125,780,934...125,988,597
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Dkk2
dickkopf WNT signaling pathway inhibitor 2
increases expression
ISO
Malathion results in increased expression of DKK2 mRNA
CTD
PMID:37047231
NCBI chr 3:131,791,027...131,886,065
Ensembl chr 3:131,791,053...131,886,065
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Dlg2
discs large MAGUK scaffold protein 2
increases expression
ISO
Malathion results in increased expression of DLG2 mRNA
CTD
PMID:37047231
NCBI chr 7:90,125,399...92,098,454
Ensembl chr 7:90,125,880...92,098,455
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Dnmt1
DNA methyltransferase 1
decreases expression
ISO
Malathion results in decreased expression of DNMT1 mRNA
CTD
PMID:36370973
NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
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Dnmt3a
DNA methyltransferase 3A
affects expression
ISO
Malathion affects the expression of DNMT3A mRNA
CTD
PMID:36370973
NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
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Dnmt3b
DNA methyltransferase 3B
affects expression
ISO
Malathion affects the expression of DNMT3B mRNA
CTD
PMID:36370973
NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
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Doc2b
double C2, beta
decreases expression
ISO
Malathion results in decreased expression of DOC2B mRNA
CTD
PMID:37047231
NCBI chr11:75,659,096...75,686,886
Ensembl chr11:75,659,792...75,686,875
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Dsp
desmoplakin
increases expression
ISO
Malathion results in increased expression of DSP mRNA
CTD
PMID:37047231
NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553
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Dspp
dentin sialophosphoprotein
decreases expression
ISO
Malathion results in decreased expression of DSPP mRNA
CTD
PMID:37047231
NCBI chr 5:104,318,569...104,327,993
Ensembl chr 5:104,318,578...104,327,993
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Dtna
dystrobrevin alpha
decreases expression
ISO
Malathion results in decreased expression of DTNA mRNA
CTD
PMID:37047231
NCBI chr18:23,443,063...23,792,776
Ensembl chr18:23,548,192...23,792,772
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Duox1
dual oxidase 1
increases expression multiple interactions
EXP
Malathion results in increased expression of DUOX1 protein Plant Extracts inhibits the reaction [Malathion results in increased expression of DUOX1 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of DUOX1 protein]
CTD
PMID:32120800
NCBI chr 2:122,143,525...122,178,454
Ensembl chr 2:122,146,153...122,178,453
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Dusp1
dual specificity phosphatase 1
decreases expression
ISO
Malathion results in decreased expression of DUSP1 mRNA
CTD
PMID:32069766
NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
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Dusp5
dual specificity phosphatase 5
increases expression
ISO
Malathion results in increased expression of DUSP5 mRNA
CTD
PMID:37047231
NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862
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Dvl1
dishevelled segment polarity protein 1
increases expression
ISO
Malathion results in increased expression of DVL1 mRNA
CTD
PMID:18204794
NCBI chr 4:155,931,829...155,943,760
Ensembl chr 4:155,931,859...155,943,760
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Ebi3
Epstein-Barr virus induced gene 3
increases expression
ISO
Malathion results in increased expression of EBI3 mRNA
CTD
PMID:37047231
NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
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Edn1
endothelin 1
increases expression
ISO
Malathion results in increased expression of EDN1 mRNA
CTD
PMID:37047231
NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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Ednrb
endothelin receptor type B
decreases expression
ISO
Malathion results in decreased expression of EDNRB mRNA
CTD
PMID:37047231
NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838
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Efcab9
EF-hand calcium binding domain 9
increases expression
ISO
Malathion results in increased expression of EFCAB9 mRNA
CTD
PMID:37047231
NCBI chr11:32,472,733...32,483,144
Ensembl chr11:32,472,751...32,482,081
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Ehbp1
EH domain binding protein 1
increases response to substance
ISO
EHBP1 gene SNP results in increased susceptibility to Malathion
CTD
PMID:23593118
NCBI chr11:21,955,825...22,237,086
Ensembl chr11:21,955,828...22,292,292
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En1
engrailed 1
decreases expression
ISO
Malathion results in decreased expression of EN1 mRNA
CTD
PMID:37047231
NCBI chr 1:120,530,246...120,535,719
Ensembl chr 1:120,530,147...120,535,721
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Enkur
enkurin, TRPC channel interacting protein
increases expression
ISO
Malathion results in increased expression of ENKUR mRNA
CTD
PMID:37047231
NCBI chr 2:21,185,542...21,210,176
Ensembl chr 2:21,185,542...21,210,176
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Epha10
Eph receptor A10
increases expression
ISO
Malathion results in increased expression of EPHA10 mRNA
CTD
PMID:37047231
NCBI chr 4:124,775,408...124,811,594
Ensembl chr 4:124,774,692...124,811,593
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Epha4
Eph receptor A4
increases expression
ISO
Malathion results in increased expression of EPHA4 mRNA
CTD
PMID:32069766
NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725
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Ephx1
epoxide hydrolase 1, microsomal
decreases expression
EXP
Malathion results in decreased expression of EPHX1 mRNA
CTD
PMID:17311802
NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
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Epop
elongin BC and polycomb repressive complex 2 associated protein
increases expression
ISO
Malathion results in increased expression of EPOP mRNA
CTD
PMID:37047231
NCBI chr11:97,518,213...97,520,542
Ensembl chr11:97,518,215...97,520,528
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Eps8l1
EPS8-like 1
increases expression
ISO
Malathion results in increased expression of EPS8L1 mRNA
CTD
PMID:32069766
NCBI chr 7:4,463,636...4,483,486
Ensembl chr 7:4,463,673...4,483,486
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Erbb4
erb-b2 receptor tyrosine kinase 4
increases expression
ISO
Malathion results in increased expression of ERBB4 mRNA
CTD
PMID:37047231
NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
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Esr1
estrogen receptor 1 (alpha)
decreases activity
ISO
Malathion results in decreased activity of ESR1 protein
CTD
PMID:22562034
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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Etv6
ets variant 6
increases expression
ISO
Malathion results in increased expression of ETV6 mRNA mutant form
CTD
PMID:28624474
NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121
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F3
coagulation factor III
increases expression
ISO
Malathion results in increased expression of F3 mRNA
CTD
PMID:37047231
NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
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Fam124a
family with sequence similarity 124, member A
increases expression
ISO
Malathion results in increased expression of FAM124A mRNA
CTD
PMID:37047231
NCBI chr14:62,793,186...62,845,935
Ensembl chr14:62,793,186...62,845,935
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Fam227b
family with sequence similarity 227, member B
decreases expression
ISO
Malathion results in decreased expression of FAM227B mRNA
CTD
PMID:37047231
NCBI chr 2:125,825,403...125,994,048
Ensembl chr 2:125,825,403...125,993,924
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Fam229b
family with sequence similarity 229, member B
decreases expression
ISO
Malathion results in decreased expression of FAM229B mRNA
CTD
PMID:37047231
NCBI chr10:38,994,800...39,009,936
Ensembl chr10:38,994,800...39,009,910
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Fgf22
fibroblast growth factor 22
decreases expression
ISO
Malathion results in decreased expression of FGF22 mRNA
CTD
PMID:37047231
NCBI chr10:79,590,887...79,593,629
Ensembl chr10:79,590,910...79,594,430
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Fgf6
fibroblast growth factor 6
increases expression
ISO
Malathion results in increased expression of FGF6 mRNA
CTD
PMID:32069766
NCBI chr 6:126,992,505...127,001,681
Ensembl chr 6:126,992,549...127,005,150
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Fgfbp1
fibroblast growth factor binding protein 1
increases expression
ISO
Malathion results in increased expression of FGFBP1 mRNA
CTD
PMID:37047231
NCBI chr 5:44,136,200...44,139,173
Ensembl chr 5:44,136,200...44,139,121
G
Fgfr1
fibroblast growth factor receptor 1
increases expression
ISO
Malathion results in increased expression of FGFR1 mRNA
CTD
PMID:32069766
NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
G
Fgg
fibrinogen gamma chain
decreases expression
ISO
Malathion results in decreased expression of FGG mRNA
CTD
PMID:37047231
NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
G
Filip1l
filamin A interacting protein 1-like
increases expression
ISO
Malathion results in increased expression of FILIP1L mRNA
CTD
PMID:37047231
NCBI chr16:57,173,376...57,393,167
Ensembl chr16:57,173,456...57,393,489
G
Flt4
FMS-like tyrosine kinase 4
increases expression
ISO
Malathion results in increased expression of FLT4 mRNA
CTD
PMID:37047231
NCBI chr11:49,500,506...49,543,566
Ensembl chr11:49,500,090...49,543,566
G
Foxo1
forkhead box O1
decreases expression multiple interactions increases methylation
ISO
Malathion results in decreased expression of FOXO1 mRNA [Malathion results in increased methylation of FOXO1 promoter] which results in decreased expression of FOXO1 mRNA
CTD
PMID:36370973
NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
G
Foxo4
forkhead box O4
increases expression
ISO
Malathion results in increased expression of FOXO4 mRNA
CTD
PMID:32069766
NCBI chr X:100,297,855...100,304,479
Ensembl chr X:100,298,134...100,304,479
G
Fshr
follicle stimulating hormone receptor
increases expression
ISO
Malathion results in increased expression of FSHR mRNA
CTD
PMID:32069766
NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
G
G6pdx
glucose-6-phosphate dehydrogenase X-linked
multiple interactions increases activity
ISO
[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein] Malathion results in increased activity of G6PD protein
CTD
PMID:27214522
NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800
G
Gad1
glutamate decarboxylase 1
affects binding
ISO
Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD1 protein
CTD
PMID:35151785
NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
G
Gad2
glutamic acid decarboxylase 2
affects binding
ISO
Malathion binds to [GAD2 protein binds to Pyridoxal Phosphate]; Malathion binds to GAD2 protein
CTD
PMID:35151785
NCBI chr 2:22,512,262...22,583,889
Ensembl chr 2:22,512,217...22,583,886
G
Galnt16
polypeptide N-acetylgalactosaminyltransferase 16
increases expression
ISO
Malathion results in increased expression of GALNT16 mRNA
CTD
PMID:37047231
NCBI chr12:80,565,245...80,650,672
Ensembl chr12:80,565,051...80,677,746
G
Garin2
golgi associated RAB2 interactor 2
decreases expression
ISO
Malathion results in decreased expression of GARIN2 mRNA
CTD
PMID:37047231
NCBI chr12:78,738,257...78,781,290
Ensembl chr12:78,738,309...78,781,290
G
Gas2
growth arrest specific 2
increases expression
ISO
Malathion results in increased expression of GAS2 mRNA
CTD
PMID:37047231
NCBI chr 7:51,511,560...51,644,753
Ensembl chr 7:51,511,763...51,644,723
G
Gata4
GATA binding protein 4
decreases expression
ISO
Malathion results in decreased expression of GATA4 mRNA
CTD
PMID:37047231
NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
G
Gbp2b
guanylate binding protein 2b
increases expression
ISO
Malathion results in increased expression of GBP1 mRNA
CTD
PMID:37047231
NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940
G
Gbp5
guanylate binding protein 5
increases expression
ISO
Malathion results in increased expression of GBP5 mRNA
CTD
PMID:37047231
NCBI chr 3:142,202,695...142,228,105
Ensembl chr 3:142,199,739...142,228,105
G
Gk
glycerol kinase
multiple interactions increases activity
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein]
CTD
PMID:25449180
NCBI chr X:84,745,543...84,820,425
Ensembl chr X:84,745,543...84,820,425
G
Gk2
glycerol kinase 2
decreases expression
ISO
Malathion results in decreased expression of GK2 mRNA
CTD
PMID:25449180
NCBI chr 5:97,602,989...97,604,882
Ensembl chr 5:97,603,001...97,604,880
G
Gm13889
predicted gene 13889
increases expression
ISO
Malathion results in increased expression of C11ORF96 mRNA
CTD
PMID:37047231
NCBI chr 2:93,786,155...93,787,445
Ensembl chr 2:93,786,155...93,787,546
G
Gm20348
predicted gene, 20348
increases expression multiple interactions
ISO
Malathion results in increased expression of TP53I3 mRNA [Malathion co-treated with Estrogens] results in increased expression of TP53I3 mRNA
CTD
PMID:18204794
NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
G
Gmnc
geminin coiled-coil domain containing
increases expression
ISO
Malathion results in increased expression of GMNC mRNA
CTD
PMID:37047231
NCBI chr16:26,775,985...26,810,424
Ensembl chr16:26,732,303...26,810,402
G
Gnai1
G protein subunit alpha i1
increases expression
ISO
Malathion results in increased expression of GNAI1 mRNA
CTD
PMID:37047231
NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
Malathion results in decreased expression of GNAI2 mRNA
CTD
PMID:32069766
NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
G
Got1l1
glutamic-oxaloacetic transaminase 1-like 1
increases expression
ISO
Malathion results in increased expression of GOT1L1 mRNA
CTD
PMID:37047231
NCBI chr 8:27,687,487...27,713,872
Ensembl chr 8:27,687,487...27,713,856
G
Gp5
glycoprotein 5 platelet
increases expression
ISO
Malathion results in increased expression of GP5 mRNA
CTD
PMID:37047231
NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597
G
Gpr179
G protein-coupled receptor 179
decreases expression
ISO
Malathion results in decreased expression of GPR179 mRNA
CTD
PMID:37047231
NCBI chr11:97,222,935...97,243,182
Ensembl chr11:97,222,935...97,242,903
G
Gps2
G protein pathway suppressor 2
decreases expression
ISO
Malathion results in decreased expression of GPS2 mRNA
CTD
PMID:32069766
NCBI chr11:69,804,805...69,807,882
Ensembl chr11:69,804,714...69,807,417
G
Gpt
glutamic pyruvic transaminase, soluble
increases activity
ISO
Malathion results in increased activity of GPT protein
CTD
PMID:25180440 PMID:36370973
NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
G
Gramd4
GRAM domain containing 4
decreases expression
ISO
Malathion results in decreased expression of GRAMD4 mRNA
CTD
PMID:32069766
NCBI chr15:85,941,896...86,021,837
Ensembl chr15:85,941,896...86,021,835
G
Grk1
G protein-coupled receptor kinase 1
increases expression
ISO
Malathion results in increased expression of GRK1 mRNA
CTD
PMID:37047231
NCBI chr 8:13,455,081...13,471,951
Ensembl chr 8:13,455,081...13,471,951
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO
Malathion results in increased expression of GSK3B mRNA
CTD
PMID:25449180
NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
G
Gsr
glutathione reductase
multiple interactions decreases activity
EXP ISO
[Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein Malathion results in decreased activity of GSR protein zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD
PMID:16718366 PMID:19429256
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
G
Gstp1
glutathione S-transferase, pi 1
decreases expression
ISO
Malathion results in decreased expression of GSTP1 mRNA
CTD
PMID:32069766
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
G
Gzmb
granzyme B
multiple interactions decreases expression
EXP
Plant Extracts inhibits the reaction [Malathion results in decreased expression of GZMB protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of GZMB protein]
CTD
PMID:32120800
NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
G
H19
H19, imprinted maternally expressed transcript
increases expression
ISO
Malathion results in increased expression of H19 mRNA
CTD
PMID:37047231
NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,131,917
G
H2-Q1
histocompatibility 2, Q region locus 1
decreases expression
ISO
Malathion results in decreased expression of HLA-A mRNA
CTD
PMID:32069766
NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075
G
H2-T23
histocompatibility 2, T region locus 23
decreases expression
ISO
Malathion results in decreased expression of HLA-E mRNA
CTD
PMID:32069766
NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747
G
Has1
hyaluronan synthase 1
increases expression
ISO
Malathion results in increased expression of HAS1 mRNA
CTD
PMID:37047231
NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467
G
Hbegf
heparin-binding EGF-like growth factor
increases expression
ISO
Malathion results in increased expression of HBEGF mRNA
CTD
PMID:37047231
NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
G
Hdc
histidine decarboxylase
affects binding
ISO
Malathion binds to [HDC protein binds to Pyridoxal Phosphate]; Malathion binds to HDC protein
CTD
PMID:35151785
NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219
G
Hilpda
hypoxia inducible lipid droplet associated
increases expression
ISO
Malathion results in increased expression of HILPDA mRNA
CTD
PMID:37047231
NCBI chr 6:29,272,487...29,275,448
Ensembl chr 6:29,272,487...29,275,445
G
Hmox1
heme oxygenase 1
increases expression
ISO
Malathion results in increased expression of HMOX1 protein
CTD
PMID:34778934
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
G
Hnmt
histamine N-methyltransferase
decreases expression
ISO
Malathion results in decreased expression of HNMT mRNA
CTD
PMID:37047231
NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406
G
Hras
Harvey rat sarcoma virus oncogene
multiple interactions increases expression
ISO
[Malathion co-treated with Estrogens] results in increased expression of HRAS mRNA Malathion results in increased expression of HRAS mRNA; Malathion results in increased expression of HRAS protein
CTD
PMID:18204794 PMID:19787260
NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
G
Hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
decreases expression multiple interactions
EXP ISO
Malathion results in decreased expression of HSD17B3 mRNA lavender oil inhibits the reaction [Malathion results in decreased expression of HSD17B3 mRNA]
CTD
PMID:30409133 PMID:36336997
NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044
G
Hsf2bp
heat shock transcription factor 2 binding protein
increases expression
ISO
Malathion results in increased expression of HSF2BP mRNA
CTD
PMID:37047231
NCBI chr17:32,163,743...32,253,869
Ensembl chr17:32,163,743...32,255,323
G
Hspb2
heat shock protein 2
increases expression
ISO
Malathion results in increased expression of HSPB2 protein
CTD
PMID:19607909
NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654
G
Htatip2
HIV-1 Tat interactive protein 2
decreases expression
ISO
Malathion results in decreased expression of HTATIP2 mRNA
CTD
PMID:32069766
NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
G
Htra4
HtrA serine peptidase 4
decreases expression
ISO
Malathion results in decreased expression of HTRA4 mRNA
CTD
PMID:37047231
NCBI chr 8:25,514,944...25,529,160
Ensembl chr 8:25,514,945...25,528,978
G
Ido1
indoleamine 2,3-dioxygenase 1
increases expression
ISO
Malathion results in increased expression of IDO1 mRNA
CTD
PMID:37047231
NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025
G
Ifi44l
interferon-induced protein 44 like
increases expression
ISO
Malathion results in increased expression of IFI44L mRNA
CTD
PMID:37047231
NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529
G
Ifnb1
interferon beta 1, fibroblast
multiple interactions
EXP
Malathion inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]
CTD
PMID:18177342
NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011
G
Ifng
interferon gamma
decreases expression multiple interactions increases expression
ISO EXP
Malathion results in decreased expression of IFNG protein Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IFNG mRNA] Plant Extracts inhibits the reaction [Malathion results in decreased expression of IFNG protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IFNG protein]
CTD
PMID:19145326 PMID:24810974 PMID:25180440 PMID:28987951 PMID:32120800
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
G
Il11
interleukin 11
increases expression
ISO
Malathion results in increased expression of IL11 mRNA
CTD
PMID:37047231
NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858
G
Il13
interleukin 13
increases expression
ISO
Malathion results in increased expression of IL13 mRNA
CTD
PMID:37047231
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
G
Il13ra2
interleukin 13 receptor, alpha 2
increases expression
ISO
Malathion results in increased expression of IL13RA2 mRNA
CTD
PMID:32069766
NCBI chr X:146,166,474...146,214,982
Ensembl chr X:146,166,472...146,212,188
G
Il1a
interleukin 1 alpha
increases expression
ISO
Malathion results in increased expression of IL1A mRNA
CTD
PMID:37047231
NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
G
Il1b
interleukin 1 beta
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]
CTD
PMID:24810974 PMID:25180440 PMID:28987951 PMID:37047231
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
G
Il1r2
interleukin 1 receptor, type II
decreases expression
ISO
Malathion results in decreased expression of IL1R2 mRNA
CTD
PMID:19784758
NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
G
Il2
interleukin 2
decreases expression multiple interactions
EXP
Malathion results in decreased expression of IL2 protein Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL2 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL2 protein]
CTD
PMID:32120800
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
G
Il23a
interleukin 23, alpha subunit p19
increases expression
ISO
Malathion results in increased expression of IL23A mRNA
CTD
PMID:37047231
NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
G
Il24
interleukin 24
increases expression
ISO
Malathion results in increased expression of IL24 mRNA
CTD
PMID:37047231
NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
G
Il36g
interleukin 36G
increases expression
ISO
Malathion results in increased expression of IL36G mRNA
CTD
PMID:37047231
NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580
G
Il4
interleukin 4
multiple interactions decreases expression
EXP
Plant Extracts inhibits the reaction [Malathion results in decreased expression of IL4 protein]; Polyphenols inhibits the reaction [Malathion results in decreased expression of IL4 protein]
CTD
PMID:32120800
NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
G
Il6
interleukin 6
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA]
CTD
PMID:24810974 PMID:25180440 PMID:37047231
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
G
Inhba
inhibin beta-A
decreases methylation increases expression
ISO
Malathion results in decreased methylation of INHBA promoter Malathion results in increased expression of INHBA mRNA
CTD
PMID:37047231
NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
G
Ins1
insulin I
increases expression
ISO
Malathion results in increased expression of INS1 protein
CTD
PMID:25449180
NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
Malathion results in increased expression of IRAK1 mRNA
CTD
PMID:32069766
NCBI chr X:73,057,520...73,067,527
Ensembl chr X:73,057,520...73,067,524
G
Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
Malathion results in increased expression of IRAK2 mRNA
CTD
PMID:37047231
NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987
G
Irx2
Iroquois homeobox 2
increases expression
ISO
Malathion results in increased expression of IRX2 mRNA
CTD
PMID:37047231
NCBI chr13:72,771,463...72,782,315
Ensembl chr13:72,776,939...72,782,317
G
Itgb8
integrin beta 8
decreases methylation increases expression
ISO
Malathion results in decreased methylation of ITGB8 promoter Malathion results in increased expression of ITGB8 mRNA
CTD
PMID:37047231
NCBI chr12:119,121,757...119,202,891
Ensembl chr12:119,121,757...119,202,537
G
Kazn
kazrin, periplakin interacting protein
decreases expression
ISO
Malathion results in decreased expression of KAZN mRNA
CTD
PMID:37047231
NCBI chr 4:141,829,701...142,801,231
Ensembl chr 4:141,829,701...142,205,056
G
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
increases expression
ISO
Malathion results in increased expression of KCNH5 mRNA
CTD
PMID:37047231
NCBI chr12:74,943,991...75,224,625
Ensembl chr12:74,943,994...75,224,106
G
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
decreases expression increases methylation
ISO
Malathion results in decreased expression of KCNMA1 mRNA Malathion results in increased methylation of KCNMA1 promoter
CTD
PMID:37047231
NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559
G
Kif6
kinesin family member 6
decreases expression
ISO
Malathion results in decreased expression of KIF6 mRNA
CTD
PMID:37047231
NCBI chr17:49,922,121...50,216,875
Ensembl chr17:49,922,164...50,216,875
G
Kmt2a
lysine (K)-specific methyltransferase 2A
increases expression increases mutagenesis
ISO
Malathion results in increased expression of KMT2A mRNA mutant form Malathion results in increased mutagenesis of KMT2A gene
CTD
PMID:28624474
NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
G
Krt14
keratin 14
increases expression
ISO
Malathion results in increased expression of KRT14 mRNA
CTD
PMID:37047231
NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374
G
Krt17
keratin 17
increases expression
ISO
Malathion results in increased expression of KRT17 mRNA
CTD
PMID:37047231
NCBI chr11:100,147,041...100,151,855
Ensembl chr11:100,147,043...100,151,855
G
Krtap27-1
keratin associated protein 27-1
increases expression
ISO
Malathion results in increased expression of KRTAP27-1 mRNA
CTD
PMID:37047231
NCBI chr16:88,467,934...88,468,612
Ensembl chr16:88,467,914...88,468,559
G
L1td1
LINE-1 type transposase domain containing 1
multiple interactions increases methylation affects expression
ISO
[Malathion results in increased methylation of L1TD1 promoter] which affects the expression of L1TD1 mRNA Malathion affects the expression of L1TD1 mRNA
CTD
PMID:36370973
NCBI chr 4:98,614,991...98,626,723
Ensembl chr 4:98,614,971...98,626,717
G
Lat
linker for activation of T cells
increases expression
ISO
Malathion results in increased expression of LAT mRNA
CTD
PMID:19784758
NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742
G
Lcorl
ligand dependent nuclear receptor corepressor-like
increases expression
ISO
Malathion results in increased expression of LCORL mRNA
CTD
PMID:37047231
NCBI chr 5:45,854,523...46,015,213 NCBI chr 5:45,877,009...45,884,920
Ensembl chr 5:45,854,523...46,014,957
G
Lelp1
late cornified envelope-like proline-rich 1
decreases expression
ISO
Malathion results in decreased expression of LELP1 mRNA
CTD
PMID:37047231
NCBI chr 3:92,042,301...92,050,061
Ensembl chr 3:92,042,304...92,050,051
G
Lemd1
LEM domain containing 1
increases expression
ISO
Malathion results in increased expression of LEMD1 mRNA
CTD
PMID:37047231
NCBI chr 1:132,118,361...132,185,120
Ensembl chr 1:132,119,169...132,186,965
G
Lgals1
lectin, galactose binding, soluble 1
decreases expression
ISO
Malathion results in decreased expression of LGALS1 mRNA
CTD
PMID:32069766
NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
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Lif
leukemia inhibitory factor
increases expression
ISO
Malathion results in increased expression of LIF mRNA
CTD
PMID:37047231
NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
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Lin28b
lin-28 homolog B
increases expression
ISO
Malathion results in increased expression of LIN28B mRNA
CTD
PMID:37047231
NCBI chr10:45,252,713...45,362,410
Ensembl chr10:45,252,716...45,362,491
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Lingo1
leucine rich repeat and Ig domain containing 1
decreases expression
ISO
Malathion results in decreased expression of LINGO1 mRNA
CTD
PMID:37047231
NCBI chr 9:56,525,743...56,704,355
Ensembl chr 9:56,525,759...56,703,752
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Lmbr1
limb region 1
increases expression
ISO
Malathion results in increased expression of LMBR1 mRNA
CTD
PMID:37047231
NCBI chr 5:29,434,800...29,583,414
Ensembl chr 5:29,481,000...29,485,295 Ensembl chr 5:29,481,000...29,485,295
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Lpcat4
lysophosphatidylcholine acyltransferase 4
increases expression
ISO
Malathion results in increased expression of LPCAT4 mRNA
CTD
PMID:32069766
NCBI chr 2:112,070,186...112,077,456
Ensembl chr 2:112,069,813...112,077,456
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Lrguk
leucine-rich repeats and guanylate kinase domain containing
decreases expression
ISO
Malathion results in decreased expression of LRGUK mRNA
CTD
PMID:37047231
NCBI chr 6:34,006,183...34,110,969
Ensembl chr 6:34,006,379...34,110,969
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Lrp3
low density lipoprotein receptor-related protein 3
decreases expression
ISO
Malathion results in decreased expression of LRP3 mRNA
CTD
PMID:37047231
NCBI chr 7:34,900,303...34,914,770
Ensembl chr 7:34,899,452...34,914,923
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Lypd1
Ly6/Plaur domain containing 1
decreases expression
ISO
Malathion results in decreased expression of LYPD1 mRNA
CTD
PMID:37047231
NCBI chr 1:125,795,359...125,841,134
Ensembl chr 1:125,795,359...125,840,838
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Lzts1
leucine zipper, putative tumor suppressor 1
increases expression
ISO
Malathion results in increased expression of LZTS1 mRNA
CTD
PMID:37047231
NCBI chr 8:69,585,311...69,636,901
Ensembl chr 8:69,585,321...69,636,877
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Lzts2
leucine zipper, putative tumor suppressor 2
decreases expression
ISO
Malathion results in decreased expression of LZTS2 mRNA
CTD
PMID:32069766
NCBI chr19:45,003,615...45,015,554
Ensembl chr19:45,002,853...45,015,550
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Macrod2
mono-ADP ribosylhydrolase 2
decreases expression
ISO
Malathion results in decreased expression of MACROD2 mRNA
CTD
PMID:37047231
NCBI chr 2:140,237,223...142,234,886
Ensembl chr 2:140,237,229...142,234,886
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Map2k3
mitogen-activated protein kinase kinase 3
decreases expression
ISO
Malathion results in decreased expression of MAP2K3 mRNA
CTD
PMID:32069766
NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
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Marchf3
membrane associated ring-CH-type finger 3
increases expression
ISO
Malathion results in increased expression of MARCHF3 mRNA
CTD
PMID:37047231
NCBI chr18:56,894,788...57,058,587
Ensembl chr18:56,894,788...57,058,620
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Mbp
myelin basic protein
decreases expression
ISO
Malathion results in decreased expression of MBP mRNA
CTD
PMID:37047231
NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
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Mcm2
minichromosome maintenance complex component 2
multiple interactions increases expression
ISO
[Malathion co-treated with Estrogens] results in increased expression of MCM2 mRNA Malathion results in increased expression of MCM2 mRNA
CTD
PMID:18204794
NCBI chr 6:88,860,456...88,875,762
Ensembl chr 6:88,860,456...88,875,762
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Meis1
Meis homeobox 1
decreases expression
ISO
Malathion results in decreased expression of MEIS1 mRNA
CTD
PMID:37047231
NCBI chr11:18,830,428...18,968,992
Ensembl chr11:18,829,817...18,968,985
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Met
met proto-oncogene
increases expression
ISO
Malathion results in increased expression of MET mRNA
CTD
PMID:37047231
NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
increases expression
ISO
Malathion results in increased expression of MFSD2A mRNA
CTD
PMID:37047231
NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981
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Mmp10
matrix metallopeptidase 10
increases expression
ISO
Malathion results in increased expression of MMP10 mRNA
CTD
PMID:37047231
NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
Malathion results in increased expression of MMP12 mRNA
CTD
PMID:37047231
NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
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Mmp1b
matrix metallopeptidase 1b (interstitial collagenase)
increases expression
ISO
Malathion results in increased expression of MMP1 mRNA
CTD
PMID:37047231
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
Malathion results in increased expression of MMP3 mRNA
CTD
PMID:37047231
NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
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Mpo
myeloperoxidase
multiple interactions increases activity
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein]
CTD
PMID:24810974 PMID:25180440
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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mt-Co1
cytochrome c oxidase I, mitochondrial
decreases expression
EXP
Malathion results in decreased expression of COX1 mRNA
CTD
PMID:18214912
NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
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mt-Co3
cytochrome c oxidase III, mitochondrial
decreases expression
EXP
Malathion results in decreased expression of COX3 mRNA
CTD
PMID:18214912
NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390
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Mt2
metallothionein 2
increases expression
ISO
Malathion results in increased expression of MT2A mRNA
CTD
PMID:37047231
NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
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Mybphl
myosin binding protein H-like
increases expression
ISO
Malathion results in increased expression of MYBPHL mRNA
CTD
PMID:37047231
NCBI chr 3:108,272,227...108,287,373
Ensembl chr 3:108,272,227...108,287,373
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Myo1b
myosin IB
increases expression
ISO
Malathion results in increased expression of MYO1B mRNA
CTD
PMID:37047231
NCBI chr 1:51,788,915...51,955,143
Ensembl chr 1:51,788,924...51,955,230
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Myzap
myocardial zonula adherens protein
increases expression
ISO
Malathion results in increased expression of MYZAP mRNA
CTD
PMID:37047231
NCBI chr 9:71,411,629...71,499,642
Ensembl chr 9:71,411,629...71,499,642
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
Malathion results in decreased expression of NDUFS7 mRNA
CTD
PMID:37047231
NCBI chr10:80,084,939...80,092,628
Ensembl chr10:80,084,955...80,092,628
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Nefh
neurofilament, heavy polypeptide
affects expression increases expression
ISO
Malathion affects the expression of NEFH mRNA Malathion results in increased expression of NEFH mRNA
CTD
PMID:22954530 PMID:28385489
NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
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Nek10
NIMA (never in mitosis gene a)- related kinase 10
decreases expression
ISO
Malathion results in decreased expression of NEK10 mRNA
CTD
PMID:37047231
NCBI chr14:7,457,704...7,666,183
Ensembl chr14:7,457,704...7,666,348
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Neu4
sialidase 4
increases expression
ISO
Malathion results in increased expression of NEU4 mRNA
CTD
PMID:37047231
NCBI chr 1:93,948,215...93,956,056
Ensembl chr 1:93,948,173...93,956,056
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Neurl3
neuralized E3 ubiquitin protein ligase 3
increases expression
ISO
Malathion results in increased expression of NEURL3 mRNA
CTD
PMID:37047231
NCBI chr 1:36,303,683...36,313,755
Ensembl chr 1:36,303,678...36,313,760
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Nfe2l2
nuclear factor, erythroid derived 2, like 2
increases activity
EXP
Malathion results in increased activity of NFE2L2 protein
CTD
PMID:30114225 PMID:30203046
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Nfib
nuclear factor I/B
decreases expression
ISO
Malathion results in decreased expression of NFIB mRNA
CTD
PMID:37047231
NCBI chr 4:82,208,410...82,424,988
Ensembl chr 4:82,208,410...82,623,987
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Ngf
nerve growth factor
multiple interactions
ISO
Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]
CTD
PMID:28385489
NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
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Ninj1
ninjurin 1
decreases expression
ISO
Malathion results in decreased expression of NINJ1 mRNA
CTD
PMID:32069766
NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720
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Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
ISO
Malathion results in decreased expression of NNT mRNA
CTD
PMID:37047231
NCBI chr13:119,472,063...119,545,793
Ensembl chr13:119,471,984...119,545,533 Ensembl chr13:119,471,984...119,545,533
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Nos2
nitric oxide synthase 2, inducible
increases expression
ISO
Malathion results in increased expression of NOS2 mRNA
CTD
PMID:20233601
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Nqo1
NAD(P)H dehydrogenase, quinone 1
increases expression
EXP
Malathion results in increased expression of NQO1 mRNA
CTD
PMID:17311802
NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
increases expression increases activity
ISO EXP
Malathion results in increased expression of NR1I3 mRNA Malathion results in increased activity of NR1I3 protein
CTD
PMID:22310298 PMID:28927721 PMID:30203046
NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
Malathion results in increased expression of NR4A1 mRNA
CTD
PMID:37047231
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression decreases methylation
ISO
Malathion results in increased expression of NR4A3 mRNA Malathion results in decreased methylation of NR4A3 promoter
CTD
PMID:37047231
NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
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Ntn1
netrin 1
increases expression
ISO
Malathion results in increased expression of NTN1 mRNA
CTD
PMID:37047231
NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649
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Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
increases expression
ISO
Malathion results in increased expression of NTRK2 mRNA
CTD
PMID:32069766
NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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Ocln
occludin
multiple interactions decreases expression
ISO
[Malathion co-treated with Lead] results in decreased expression of OCLN protein Malathion results in decreased expression of OCLN protein
CTD
PMID:20970449
NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
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Ocstamp
osteoclast stimulatory transmembrane protein
increases expression
ISO
Malathion results in increased expression of OCSTAMP mRNA
CTD
PMID:37047231
NCBI chr 2:165,237,370...165,242,314
Ensembl chr 2:165,235,680...165,242,325
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Odam
odontogenic, ameloblast asssociated
decreases expression
ISO
Malathion results in decreased expression of ODAM mRNA
CTD
PMID:37047231
NCBI chr 5:88,032,869...88,042,668
Ensembl chr 5:88,032,888...88,042,033
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Odf2l
outer dense fiber of sperm tails 2-like
decreases expression
ISO
Malathion results in decreased expression of ODF2L mRNA
CTD
PMID:37047231
NCBI chr 3:144,824,330...144,859,676
Ensembl chr 3:144,824,349...144,859,676
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Omg
oligodendrocyte myelin glycoprotein
affects expression
ISO
Malathion affects the expression of OMG mRNA
CTD
PMID:37047231
NCBI chr11:79,391,808...79,394,908
Ensembl chr11:79,391,808...79,394,910
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Opn5
opsin 5
decreases expression
ISO
Malathion results in decreased expression of OPN5 mRNA
CTD
PMID:37047231
NCBI chr17:42,867,670...42,922,321
Ensembl chr17:42,867,674...42,922,286
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Or2at4
olfactory receptor family 2 subfamily AT member 4
decreases expression
ISO
Malathion results in decreased expression of OR2AT4 mRNA
CTD
PMID:37047231
NCBI chr 7:99,384,352...99,385,302
Ensembl chr 7:99,379,480...99,385,606
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Or2w3
olfactory receptor family 2 subfamily W member 3
increases expression
ISO
Malathion results in increased expression of OR2W3 mRNA
CTD
PMID:37047231
NCBI chr11:58,556,387...58,557,370
Ensembl chr11:58,549,608...58,560,354
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Or4d1
olfactory receptor family 4 subfamily D member 1
decreases expression
ISO
Malathion results in decreased expression of OR4D1 mRNA
CTD
PMID:37047231
NCBI chr11:87,804,746...87,805,829
Ensembl chr11:87,804,094...87,811,793
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Or4f7
olfactory receptor family 4 subfamily F member 7
decreases expression
ISO
Malathion results in decreased expression of OR4F29 mRNA
CTD
PMID:37047231
NCBI chr 2:111,644,131...111,645,069
Ensembl chr 2:111,642,592...111,650,685
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Or6c2
olfactory receptor family 6 subfamily C member 2
decreases expression
ISO
Malathion results in decreased expression of OR6C2 mRNA
CTD
PMID:37047231
NCBI chr10:129,362,098...129,363,036
Ensembl chr10:129,357,661...129,364,222
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Or9g4
olfactory receptor family 9 subfamily G member 4
decreases expression
ISO
Malathion results in decreased expression of OR9G4 mRNA
CTD
PMID:37047231
NCBI chr 2:85,504,555...85,509,085
Ensembl chr 2:85,504,001...85,509,111
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P2rx1
purinergic receptor P2X, ligand-gated ion channel, 1
increases expression
ISO
Malathion results in increased expression of P2RX1 mRNA
CTD
PMID:19784758
NCBI chr11:72,889,882...72,906,026
Ensembl chr11:72,889,929...72,906,026
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Palmd
palmdelphin
decreases expression
ISO
Malathion results in decreased expression of PALMD mRNA
CTD
PMID:37047231
NCBI chr 3:116,711,911...116,762,896
Ensembl chr 3:116,711,907...116,762,636
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Parp1
poly (ADP-ribose) polymerase family, member 1
increases cleavage multiple interactions
EXP
Malathion results in increased cleavage of PARP1 protein Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein]
CTD
PMID:29027213
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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Pax1
paired box 1
increases expression
ISO
Malathion results in increased expression of PAX1 mRNA
CTD
PMID:32069766
NCBI chr 2:147,203,850...147,216,972
Ensembl chr 2:147,203,845...147,235,215
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Pcdh15
protocadherin 15
decreases expression
ISO
Malathion results in decreased expression of PCDH15 mRNA
CTD
PMID:37047231
NCBI chr10:72,932,003...74,485,663
Ensembl chr10:72,935,174...74,485,569
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Pcdhb19
protocadherin beta 19
decreases expression
ISO
Malathion results in decreased expression of PCDHB12 mRNA
CTD
PMID:37047231
NCBI chr18:37,630,049...37,637,181
Ensembl chr18:37,630,044...37,637,181
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Pcdhgb1
protocadherin gamma subfamily B, 1
increases expression
ISO
Malathion results in increased expression of PCDHGB1 mRNA
CTD
PMID:37047231
NCBI chr18:37,813,325...37,974,923
Ensembl chr18:37,813,286...37,974,923
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Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA]
CTD
PMID:25449180
NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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Pcna
proliferating cell nuclear antigen
multiple interactions increases expression
ISO
Atropine inhibits the reaction [Malathion results in increased expression of PCNA]
CTD
PMID:12762645
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Pde6c
phosphodiesterase 6C, cGMP specific, cone, alpha prime
decreases expression
ISO
Malathion results in decreased expression of PDE6C mRNA
CTD
PMID:37047231
NCBI chr19:38,121,220...38,172,391
Ensembl chr19:38,121,229...38,172,406
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Pdia2
protein disulfide isomerase associated 2
decreases expression
ISO
Malathion results in decreased expression of PDIA2 mRNA
CTD
PMID:37047231
NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061
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Pebp1
phosphatidylethanolamine binding protein 1
decreases expression
ISO
Malathion results in decreased expression of PEBP1 mRNA
CTD
PMID:32069766
NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
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Peg10
paternally expressed 10
increases expression
ISO
Malathion results in increased expression of PEG10 mRNA
CTD
PMID:37047231
NCBI chr 6:4,747,306...4,760,517
Ensembl chr 6:4,747,306...4,760,517
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Pfn1
profilin 1
decreases expression
ISO
Malathion results in decreased expression of PFN1 mRNA
CTD
PMID:32069766
NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470
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Phb1
prohibitin 1
decreases expression
ISO
Malathion results in decreased expression of PHB1 mRNA
CTD
PMID:32069766
NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
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Pitx1
paired-like homeodomain transcription factor 1
decreases expression
ISO
Malathion results in decreased expression of PITX1 mRNA
CTD
PMID:37047231
NCBI chr13:55,972,857...55,984,002
Ensembl chr13:55,972,864...55,984,005
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Plat
plasminogen activator, tissue
decreases expression
ISO
Malathion results in decreased expression of PLAT mRNA
CTD
PMID:16079077
NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
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Plau
plasminogen activator, urokinase
increases expression
ISO
Malathion results in increased expression of PLAU mRNA
CTD
PMID:32069766
NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
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Plaur
plasminogen activator, urokinase receptor
increases expression
ISO
Malathion results in increased expression of PLAUR mRNA
CTD
PMID:37047231
NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
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Plcb4
phospholipase C, beta 4
increases expression
ISO
Malathion results in increased expression of PLCB4 mRNA
CTD
PMID:37047231
NCBI chr 2:135,500,523...135,856,522
Ensembl chr 2:135,500,931...135,856,513
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Plekhd1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
decreases expression
ISO
Malathion results in decreased expression of PLEKHD1 mRNA
CTD
PMID:37047231
NCBI chr12:80,739,375...80,770,990
Ensembl chr12:80,739,365...80,770,988
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Plin1
perilipin 1
increases expression
ISO
Malathion results in increased expression of PLIN1 mRNA
CTD
PMID:37047231
NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651
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Plin2
perilipin 2
increases expression
ISO
Malathion results in increased expression of PLIN2 mRNA
CTD
PMID:37047231
NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
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Plp1
proteolipid protein (myelin) 1
decreases expression
ISO
Malathion results in decreased expression of PLP1 mRNA
CTD
PMID:37047231
NCBI chr X:135,720,897...135,739,331
Ensembl chr X:135,723,420...135,740,482
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Pls3
plastin 3 (T-isoform)
increases expression
ISO
Malathion results in increased expression of PLS3 mRNA
CTD
PMID:37047231
NCBI chr X:74,829,259...74,918,788
Ensembl chr X:74,829,260...74,918,788
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Plvap
plasmalemma vesicle associated protein
decreases expression
ISO
Malathion results in decreased expression of PLVAP mRNA
CTD
PMID:37047231
NCBI chr 8:71,950,397...71,964,446
Ensembl chr 8:71,950,409...71,964,396
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Pml
promyelocytic leukemia
decreases expression
ISO
Malathion results in decreased expression of PML mRNA
CTD
PMID:32069766
NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
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Ppara
peroxisome proliferator activated receptor alpha
decreases expression
EXP
Malathion results in decreased expression of PPARA mRNA
CTD
PMID:25689681
NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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Prkd1
protein kinase D1
increases expression
ISO
Malathion results in increased expression of PRKD1 mRNA
CTD
PMID:32069766
NCBI chr12:50,388,009...50,696,075
Ensembl chr12:50,388,014...50,695,881
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Prox2
prospero homeobox 2
decreases expression
ISO
Malathion results in decreased expression of PROX2 mRNA
CTD
PMID:37047231
NCBI chr12:85,132,584...85,157,606
Ensembl chr12:85,133,159...85,157,533
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Proz
protein Z, vitamin K-dependent plasma glycoprotein
decreases expression
ISO
Malathion results in decreased expression of PROZ mRNA
CTD
PMID:37047231
NCBI chr 8:13,110,583...13,126,026
Ensembl chr 8:13,110,914...13,126,026
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Ptcra
pre T cell antigen receptor alpha
decreases expression
ISO
Malathion results in decreased expression of PTCRA mRNA
CTD
PMID:37047231
NCBI chr17:47,066,589...47,074,659
Ensembl chr17:47,066,589...47,074,638
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Malathion results in increased expression of PTGS2 mRNA; Malathion results in increased expression of PTGS2 protein
CTD
PMID:30673264
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Pygl
liver glycogen phosphorylase
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA]
CTD
PMID:25449180
NCBI chr12:70,237,589...70,274,457
Ensembl chr12:70,237,585...70,278,262
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Rab11fip3
RAB11 family interacting protein 3 (class II)
increases expression
ISO
Malathion results in increased expression of RAB11FIP3 mRNA
CTD
PMID:32069766
NCBI chr17:26,208,010...26,289,010
Ensembl chr17:26,208,010...26,288,529
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Rab3c
RAB3C, member RAS oncogene family
decreases expression
ISO
Malathion results in decreased expression of RAB3C mRNA
CTD
PMID:37047231
NCBI chr13:110,190,721...110,417,530
Ensembl chr13:110,190,721...110,417,530
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Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
increases expression
ISO
Malathion results in increased expression of RAPGEF5 mRNA
CTD
PMID:37047231
NCBI chr12:117,480,146...117,723,472
Ensembl chr12:117,480,099...117,723,472
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Rbp3
retinol binding protein 3, interstitial
decreases expression
ISO
Malathion results in decreased expression of RBP3 mRNA
CTD
PMID:37047231
NCBI chr14:33,675,960...33,686,176
Ensembl chr14:33,675,960...33,686,173
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Rbp7
retinol binding protein 7, cellular
decreases expression
ISO
Malathion results in decreased expression of RBP7 mRNA
CTD
PMID:37047231
NCBI chr 4:149,534,144...149,550,919
Ensembl chr 4:149,534,144...149,539,435
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Redic1
regulator of DNA class I crossover intermediates 1
decreases expression
ISO
Malathion results in decreased expression of REDIC1 mRNA
CTD
PMID:37047231
NCBI chr15:91,083,654...91,146,291
Ensembl chr15:91,083,697...91,145,097
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Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
increases expression multiple interactions
ISO
Malathion results in increased expression of RELA mRNA Taurine inhibits the reaction [Malathion results in increased expression of RELA mRNA]
CTD
PMID:28987951 PMID:30673264
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Reln
reelin
increases expression
ISO
Malathion results in increased expression of RELN mRNA
CTD
PMID:37047231
NCBI chr 5:22,089,452...22,549,703
Ensembl chr 5:22,089,452...22,549,700
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Rfc3
replication factor C (activator 1) 3
decreases expression
ISO
Malathion results in decreased expression of RFC3 mRNA
CTD
PMID:16079077
NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
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Rft1
RFT1 homolog
decreases expression
ISO
Malathion results in decreased expression of RFT1 mRNA
CTD
PMID:37047231
NCBI chr14:30,375,041...30,413,274
Ensembl chr14:30,376,317...30,413,274
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Rhoa
ras homolog family member A
decreases activity
EXP
Malathion results in decreased activity of RHOA protein
CTD
PMID:37270087
NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
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Rhox13
reproductive homeobox 13
increases expression
ISO
Malathion results in increased expression of RHOXF1 mRNA
CTD
PMID:37047231
NCBI chr X:37,210,059...37,218,850
Ensembl chr X:37,210,096...37,218,844
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Rimbp2
RIMS binding protein 2
decreases expression
ISO
Malathion results in decreased expression of RIMBP2 mRNA
CTD
PMID:37047231
NCBI chr 5:128,834,852...129,030,636
Ensembl chr 5:128,834,855...129,030,550
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Rnase6
ribonuclease, RNase A family, 6
increases expression
ISO
Malathion results in increased expression of RNASE6 mRNA
CTD
PMID:19784758
NCBI chr14:51,361,365...51,369,644
Ensembl chr14:51,361,365...51,369,644
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Rnf170
ring finger protein 170
increases expression
ISO
Malathion results in increased expression of RNF170 mRNA
CTD
PMID:37047231
NCBI chr 8:26,609,396...26,633,903
Ensembl chr 8:26,609,396...26,641,818
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Rnf183
ring finger protein 183
increases expression
ISO
Malathion results in increased expression of RNF183 mRNA
CTD
PMID:37047231
NCBI chr 4:62,345,777...62,353,487
Ensembl chr 4:62,345,777...62,353,489
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Robo4
roundabout guidance receptor 4
decreases expression
ISO
Malathion results in decreased expression of ROBO4 mRNA
CTD
PMID:37047231
NCBI chr 9:37,313,198...37,325,319
Ensembl chr 9:37,313,193...37,326,411
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Rph3a
rabphilin 3A
decreases expression
ISO
Malathion results in decreased expression of RPH3A mRNA
CTD
PMID:37047231
NCBI chr 5:121,078,562...121,184,249
Ensembl chr 5:121,078,562...121,148,155
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Rrad
Ras-related associated with diabetes
increases expression
ISO
Malathion results in increased expression of RRAD mRNA
CTD
PMID:37047231
NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
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Rs1
retinoschisis (X-linked, juvenile) 1 (human)
increases expression
ISO
Malathion results in increased expression of RS1 mRNA
CTD
PMID:37047231
NCBI chr X:159,548,815...159,584,800
Ensembl chr X:159,551,009...159,582,659
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Rsad2
radical S-adenosyl methionine domain containing 2
increases expression
ISO
Malathion results in increased expression of RSAD2 mRNA
CTD
PMID:37047231
NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
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Rspo2
R-spondin 2
decreases expression
ISO
Malathion results in decreased expression of RSPO2 mRNA
CTD
PMID:37047231
NCBI chr15:42,884,184...43,034,990
Ensembl chr15:42,884,190...43,034,222
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Runx1
runt related transcription factor 1
increases expression
ISO
Malathion results in increased expression of RUNX1 mRNA mutant form
CTD
PMID:28624474
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
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S100a1
S100 calcium binding protein A1
decreases expression
ISO
Malathion results in decreased expression of S100A1 mRNA
CTD
PMID:37047231
NCBI chr 3:90,418,341...90,421,637
Ensembl chr 3:90,418,341...90,421,699
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Scg5
secretogranin V
increases expression
ISO
Malathion results in increased expression of SCG5 mRNA
CTD
PMID:37047231
NCBI chr 2:113,606,708...113,659,423
Ensembl chr 2:113,606,707...113,659,466
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Scn9a
sodium channel, voltage-gated, type IX, alpha
decreases expression
ISO
Malathion results in decreased expression of SCN9A mRNA
CTD
PMID:37047231
NCBI chr 2:66,310,424...66,465,456
Ensembl chr 2:66,310,424...66,465,306
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Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
increases expression
ISO
Malathion results in increased expression of SERPINB2 mRNA
CTD
PMID:37047231
NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208
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Sftpb
surfactant associated protein B
decreases expression
ISO
Malathion results in decreased expression of SFTPB mRNA
CTD
PMID:37047231
NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354
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Sgpp2
sphingosine-1-phosphate phosphatase 2
increases expression
ISO
Malathion results in increased expression of SGPP2 mRNA
CTD
PMID:37047231
NCBI chr 1:78,286,186...78,396,926
Ensembl chr 1:78,286,982...78,396,926
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Shc1
src homology 2 domain-containing transforming protein C1
increases expression
ISO
Malathion results in increased expression of SHC1 mRNA
CTD
PMID:32069766
NCBI chr 3:89,325,858...89,337,336
Ensembl chr 3:89,325,750...89,337,334
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Shisa3
shisa family member 3
increases expression
ISO
Malathion results in increased expression of SHISA3 mRNA
CTD
PMID:37047231
NCBI chr 5:67,765,226...67,771,330
Ensembl chr 5:67,765,225...67,780,895
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Shisa9
shisa family member 9
increases expression
ISO
Malathion results in increased expression of SHISA9 mRNA
CTD
PMID:37047231
NCBI chr16:11,801,457...12,088,768
Ensembl chr16:11,801,977...12,088,766
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Shtn1
shootin 1
decreases expression
ISO
Malathion results in decreased expression of SHTN1 mRNA
CTD
PMID:37047231
NCBI chr19:58,961,790...59,064,536
Ensembl chr19:58,961,788...59,064,532
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Slc14a1
solute carrier family 14 (urea transporter), member 1
decreases expression
ISO
Malathion results in decreased expression of SLC14A1 mRNA
CTD
PMID:37047231
NCBI chr18:78,143,306...78,185,334
Ensembl chr18:78,143,306...78,185,334
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Slc22a2
solute carrier family 22 (organic cation transporter), member 2
multiple interactions
ISO
Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]
CTD
PMID:23770354
NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
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Slc22a6
solute carrier family 22 (organic anion transporter), member 6
multiple interactions
ISO
Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
CTD
PMID:21561794
NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
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Slc4a5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
decreases expression
ISO
Malathion results in decreased expression of SLC4A5 mRNA
CTD
PMID:37047231
NCBI chr 6:83,184,561...83,281,927
Ensembl chr 6:83,196,810...83,281,927
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Slco4a1
solute carrier organic anion transporter family, member 4a1
increases expression
ISO
Malathion results in increased expression of SLCO4A1 mRNA
CTD
PMID:37047231
NCBI chr 2:180,098,019...180,116,646
Ensembl chr 2:180,098,038...180,116,660
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Smim32
small integral membrane protein 32
decreases expression
ISO
Malathion results in decreased expression of SMIM32 mRNA
CTD
PMID:37047231
NCBI chr13:56,897,857...56,901,640
Ensembl chr13:56,900,184...56,901,640
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Snca
synuclein, alpha
increases expression multiple interactions
ISO
Malathion results in increased expression of SNCA mRNA; Malathion results in increased expression of SNCA protein crocin inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; crocin inhibits the reaction [Malathion results in increased expression of SNCA protein]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA mRNA]; Levodopa inhibits the reaction [Malathion results in increased expression of SNCA protein]
CTD
PMID:35274200
NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
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Sntg1
syntrophin, gamma 1
decreases expression
ISO
Malathion results in decreased expression of SNTG1 mRNA
CTD
PMID:37047231
NCBI chr 1:8,429,963...9,371,882
Ensembl chr 1:8,431,699...9,370,103
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Socs3
suppressor of cytokine signaling 3
decreases expression
ISO
Malathion results in decreased expression of SOCS3 mRNA
CTD
PMID:32069766
NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
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Sod1
superoxide dismutase 1, soluble
increases activity multiple interactions decreases expression
ISO EXP
Malathion results in increased activity of SOD1 protein alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein] lavender oil inhibits the reaction [Malathion results in decreased expression of SOD1 protein]
CTD
PMID:20194575 PMID:30409133
NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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Sod2
superoxide dismutase 2, mitochondrial
multiple interactions decreases expression
ISO EXP
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; Malathion results in increased expression of and results in increased activity of SOD2 protein lavender oil inhibits the reaction [Malathion results in decreased expression of SOD2 protein]
CTD
PMID:20194575 PMID:30409133
NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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Spata17
spermatogenesis associated 17
decreases expression
ISO
Malathion results in decreased expression of SPATA17 mRNA
CTD
PMID:37047231
NCBI chr 1:186,741,811...186,947,705
Ensembl chr 1:186,776,845...186,947,662
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Spdya
speedy/RINGO cell cycle regulator family, member A
increases expression
ISO
Malathion results in increased expression of SPDYA mRNA
CTD
PMID:37047231
NCBI chr17:71,833,890...71,896,528
Ensembl chr17:71,859,056...71,896,528
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Spink13
serine peptidase inhibitor, Kazal type 13
decreases expression
ISO
Malathion results in decreased expression of SPINK13 mRNA
CTD
PMID:37047231
NCBI chr18:62,740,570...62,874,458
Ensembl chr18:62,740,606...62,874,458
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Spink4
serine peptidase inhibitor, Kazal type 4
decreases expression
ISO
Malathion results in decreased expression of SPINK4 mRNA
CTD
PMID:37047231
NCBI chr 4:40,920,056...40,931,395
Ensembl chr 4:40,920,052...40,931,395
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Srsf5
serine and arginine-rich splicing factor 5
decreases expression
ISO
Malathion results in decreased expression of SRSF5 mRNA
CTD
PMID:19784758
NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281
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Sspo
SCO-spondin
decreases expression
ISO
Malathion results in decreased expression of SSPOP mRNA
CTD
PMID:37047231
NCBI chr 6:48,423,164...48,478,196
Ensembl chr 6:48,425,163...48,478,184
G
Sst
somatostatin
decreases expression
ISO
Malathion results in decreased expression of SST mRNA
CTD
PMID:37047231
NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
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Sstr2
somatostatin receptor 2
increases expression
ISO
Malathion results in increased expression of SSTR2 mRNA
CTD
PMID:37047231
NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854
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St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
increases expression
ISO
Malathion results in increased expression of ST6GAL2 mRNA
CTD
PMID:37047231
NCBI chr17:55,752,071...55,821,582
Ensembl chr17:55,752,383...55,821,582
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St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
increases expression
ISO
Malathion results in increased expression of ST8SIA1 mRNA
CTD
PMID:19784758
NCBI chr 6:142,767,267...142,935,247
Ensembl chr 6:142,767,271...142,910,178
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St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
increases expression
ISO
Malathion results in increased expression of ST8SIA4 mRNA
CTD
PMID:37047231
NCBI chr 1:95,515,407...95,595,473
Ensembl chr 1:95,515,407...95,595,296
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Star
steroidogenic acute regulatory protein
multiple interactions decreases expression
EXP
lavender oil inhibits the reaction [Malathion results in decreased expression of STAR mRNA]
CTD
PMID:30409133
NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
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Stat3
signal transducer and activator of transcription 3
decreases phosphorylation
ISO
Malathion results in decreased phosphorylation of STAT3 protein
CTD
PMID:34778934
NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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Stat5b
signal transducer and activator of transcription 5B
decreases activity
EXP
Malathion results in decreased activity of STAT5B protein
CTD
PMID:30114225
NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550
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Stk36
serine/threonine kinase 36
decreases expression
ISO
Malathion results in decreased expression of STK36 mRNA
CTD
PMID:37047231
NCBI chr 1:74,640,583...74,676,053
Ensembl chr 1:74,640,604...74,676,053
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Stra6
stimulated by retinoic acid gene 6
decreases expression
ISO
Malathion results in decreased expression of STRA6 mRNA
CTD
PMID:37047231
NCBI chr 9:57,971,076...58,061,287
Ensembl chr 9:57,971,071...58,061,279
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Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
increases expression
ISO
Malathion results in increased expression of TCF7L1 mRNA
CTD
PMID:37047231
NCBI chr 6:72,603,354...72,766,028
Ensembl chr 6:72,603,361...72,766,237
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Tchhl1
trichohyalin-like 1
decreases expression
ISO
Malathion results in decreased expression of TCHHL1 mRNA
CTD
PMID:37047231
NCBI chr 3:93,376,061...93,379,287
Ensembl chr 3:93,376,061...93,379,287
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Tdrd1
tudor domain containing 1
increases expression
ISO
Malathion results in increased expression of TDRD1 mRNA
CTD
PMID:37047231
NCBI chr19:56,814,603...56,858,444
Ensembl chr19:56,814,641...56,858,444
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Tdrd6
tudor domain containing 6
increases expression
ISO
Malathion results in increased expression of TDRD6 mRNA
CTD
PMID:37047231
NCBI chr17:43,926,225...43,942,737
Ensembl chr17:43,926,226...43,941,190
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Tdrp
testis development related protein
decreases expression
ISO
Malathion results in decreased expression of TDRP mRNA
CTD
PMID:37047231
NCBI chr 8:14,002,008...14,025,484
Ensembl chr 8:14,002,008...14,025,032
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Tek
TEK receptor tyrosine kinase
increases expression
ISO
Malathion results in increased expression of TEK mRNA
CTD
PMID:32069766
NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
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Tet1
tet methylcytosine dioxygenase 1
affects expression
ISO
Malathion affects the expression of TET1 mRNA
CTD
PMID:36370973
NCBI chr10:62,640,349...62,723,242
Ensembl chr10:62,640,349...62,744,775
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Tet2
tet methylcytosine dioxygenase 2
decreases expression
ISO
Malathion results in decreased expression of TET2 mRNA
CTD
PMID:36370973
NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900
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Tet3
tet methylcytosine dioxygenase 3
affects expression
ISO
Malathion affects the expression of TET3 mRNA
CTD
PMID:36370973
NCBI chr 6:83,339,355...83,434,190
Ensembl chr 6:83,339,355...83,436,066
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Tfpi2
tissue factor pathway inhibitor 2
increases expression
ISO
Malathion results in increased expression of TFPI2 mRNA
CTD
PMID:37047231
NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919
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Tfrc
transferrin receptor
increases expression
ISO
Malathion results in increased expression of TFRC mRNA
CTD
PMID:32069766
NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
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Tg
thyroglobulin
decreases expression
ISO
Malathion results in decreased expression of TG mRNA; Malathion results in decreased expression of TG protein
CTD
PMID:29143548
NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570
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Tifab
TRAF-interacting protein with forkhead-associated domain, family member B
decreases expression
ISO
Malathion results in decreased expression of TIFAB mRNA
CTD
PMID:37047231
NCBI chr13:56,318,917...56,326,816
Ensembl chr13:56,321,517...56,326,698
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Timp3
tissue inhibitor of metalloproteinase 3
decreases expression
ISO
Malathion results in decreased expression of TIMP3 mRNA
CTD
PMID:19784758
NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370
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Tjp1
tight junction protein 1
multiple interactions decreases expression
ISO
[Malathion co-treated with Lead] results in decreased expression of TJP1 protein Malathion results in decreased expression of TJP1 protein
CTD
PMID:20970449
NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
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Tjp2
tight junction protein 2
multiple interactions decreases expression
ISO
[Malathion co-treated with Lead] results in decreased expression of TJP2 protein Malathion results in decreased expression of TJP2 protein
CTD
PMID:20970449
NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
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Tlr4
toll-like receptor 4
increases expression multiple interactions
EXP
Malathion results in increased expression of TLR4 protein Plant Extracts inhibits the reaction [Malathion results in increased expression of TLR4 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TLR4 protein]
CTD
PMID:32120800
NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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Tlr8
toll-like receptor 8
increases expression
ISO
Malathion results in increased expression of TLR8 mRNA
CTD
PMID:32069766
NCBI chr X:166,024,119...166,047,325
Ensembl chr X:166,025,692...166,047,325
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Tmem114
transmembrane protein 114
decreases expression
ISO
Malathion results in decreased expression of TMEM114 mRNA
CTD
PMID:37047231
NCBI chr16:8,227,140...8,243,000
Ensembl chr16:8,227,139...8,243,000
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Tmem158
transmembrane protein 158
increases expression
ISO
Malathion results in increased expression of TMEM158 mRNA
CTD
PMID:37047231
NCBI chr 9:123,088,122...123,089,854
Ensembl chr 9:123,088,118...123,089,829
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Tmem241
transmembrane protein 241
decreases expression
ISO
Malathion results in decreased expression of TMEM241 mRNA
CTD
PMID:37047231
NCBI chr18:12,113,193...12,254,604
Ensembl chr18:12,097,507...12,254,594
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Tmem65
transmembrane protein 65
increases expression
ISO
Malathion results in increased expression of TMEM65 mRNA
CTD
PMID:37047231
NCBI chr15:58,654,118...58,695,510
Ensembl chr15:58,654,118...58,695,487
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Tnf
tumor necrosis factor
multiple interactions increases expression
ISO
Taurine inhibits the reaction [Malathion results in increased expression of TNF mRNA]
CTD
PMID:28987951 PMID:37047231
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfaip6
tumor necrosis factor alpha induced protein 6
increases expression
ISO
Malathion results in increased expression of TNFAIP6 mRNA
CTD
PMID:37047231
NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
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Tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
decreases expression
ISO
Malathion results in decreased expression of TNFAIP8L3 mRNA
CTD
PMID:37047231
NCBI chr 9:53,932,890...53,975,695
Ensembl chr 9:53,930,689...53,975,672
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Tnfsf15
tumor necrosis factor (ligand) superfamily, member 15
affects expression
ISO
Malathion affects the expression of TNFSF15 mRNA
CTD
PMID:37047231
NCBI chr 4:63,642,837...63,663,296
Ensembl chr 4:63,642,840...63,663,350
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Tnip3
TNFAIP3 interacting protein 3
increases expression
ISO
Malathion results in increased expression of TNIP3 mRNA
CTD
PMID:37047231
NCBI chr 6:65,567,382...65,611,024
Ensembl chr 6:65,502,297...65,611,024
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Tpr
translocated promoter region, nuclear basket protein
increases expression
ISO
Malathion results in increased expression of TPR mRNA
CTD
PMID:32069766
NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686
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Tram1l1
translocation associated membrane protein 1-like 1
increases expression
ISO
Malathion results in increased expression of TRAM1L1 mRNA
CTD
PMID:37047231
NCBI chr 3:124,114,686...124,116,909
Ensembl chr 3:124,114,504...124,118,392
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Trim35
tripartite motif-containing 35
decreases expression
ISO
Malathion results in decreased expression of TRIM35 mRNA
CTD
PMID:32069766
NCBI chr14:66,534,474...66,548,873
Ensembl chr14:66,534,480...66,548,873
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Trp53
transformation related protein 53
multiple interactions increases expression
ISO EXP
Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein] Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 protein Malathion results in increased expression of TRP53 protein [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA] Plant Extracts inhibits the reaction [Malathion results in increased expression of TRP53 protein]; Polyphenols inhibits the reaction [Malathion results in increased expression of TRP53 protein]
CTD
PMID:12505448 PMID:12762645 PMID:18204794 PMID:19787260 PMID:21628957 PMID:32120800 More...
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Trpc1
transient receptor potential cation channel, subfamily C, member 1
increases expression
ISO
Malathion results in increased expression of TRPC1 mRNA; Malathion results in increased expression of TRPC1 protein
CTD
PMID:22674931
NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428
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Trpc4
transient receptor potential cation channel, subfamily C, member 4
increases expression decreases expression
ISO
Malathion results in increased expression of TRPC4 mRNA; Malathion results in increased expression of TRPC4 protein Malathion results in decreased expression of TRPC4 mRNA
CTD
PMID:22674931 PMID:37047231
NCBI chr 3:54,063,441...54,225,892
Ensembl chr 3:54,063,456...54,225,892
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Trpc5os
transient receptor potential cation channel, subfamily C, member 5, opposite strand
increases expression
ISO
Malathion results in increased expression of TRPC5OS mRNA
CTD
PMID:37047231
NCBI chr X:143,238,872...143,260,059
Ensembl chr X:143,239,577...143,260,062
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Trpd52l3
tumor protein D52-like 3
decreases expression
ISO
Malathion results in decreased expression of TPD52L3 mRNA
CTD
PMID:37047231
NCBI chr19:29,981,190...29,983,420
Ensembl chr19:29,981,190...29,983,418
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Tshr
thyroid stimulating hormone receptor
decreases expression
ISO
Malathion results in decreased expression of TSHR protein
CTD
PMID:29143548
NCBI chr12:91,367,767...91,507,283
Ensembl chr12:91,351,337...91,516,582
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Ttc9
tetratricopeptide repeat domain 9
decreases expression
ISO
Malathion results in decreased expression of TTC9 mRNA
CTD
PMID:37047231
NCBI chr12:81,678,023...81,714,331
Ensembl chr12:81,678,023...81,714,331
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Tusc2
tumor suppressor 2, mitochondrial calcium regulator
decreases expression
ISO
Malathion results in decreased expression of TUSC2 mRNA
CTD
PMID:32069766
NCBI chr 9:107,440,454...107,443,307
Ensembl chr 9:107,440,454...107,443,311
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Twist1
twist basic helix-loop-helix transcription factor 1
increases expression
ISO
Malathion results in increased expression of TWIST1 mRNA
CTD
PMID:32069766
NCBI chr12:34,007,670...34,009,830
Ensembl chr12:34,007,670...34,009,828
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Txnrd3
thioredoxin reductase 3
decreases expression
ISO
Malathion results in decreased expression of TXNRD3 mRNA
CTD
PMID:37047231
NCBI chr 6:89,620,970...89,652,511
Ensembl chr 6:89,620,970...89,652,511
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Tyms
thymidylate synthase
decreases expression
ISO
Malathion results in decreased expression of TYMS mRNA
CTD
PMID:16079077
NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
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Ubd
ubiquitin D
increases expression
ISO
Malathion results in increased expression of UBD mRNA
CTD
PMID:37047231
NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986
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Umodl1
uromodulin-like 1
increases expression
ISO
Malathion results in increased expression of UMODL1 mRNA
CTD
PMID:37047231
NCBI chr17:31,173,614...31,229,684
Ensembl chr17:31,173,614...31,229,684
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Usp2
ubiquitin specific peptidase 2
increases expression
ISO
Malathion results in increased expression of USP2 mRNA
CTD
PMID:37047231
NCBI chr 9:43,978,318...44,006,924
Ensembl chr 9:43,978,318...44,006,924
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Usp27x
ubiquitin specific peptidase 27, X chromosome
increases expression
ISO
Malathion results in increased expression of USP27X mRNA
CTD
PMID:37047231
NCBI chr X:7,238,830...7,242,069
Ensembl chr X:7,237,513...7,242,069
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Vhl
von Hippel-Lindau tumor suppressor
decreases expression
ISO
Malathion results in decreased expression of VHL mRNA
CTD
PMID:32069766
NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
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Vpreb3
V-set pre-B cell surrogate light chain 3
increases expression
ISO
Malathion results in increased expression of VPREB3 mRNA
CTD
PMID:32069766
NCBI chr10:75,778,859...75,785,491
Ensembl chr10:75,778,891...75,785,491
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Wbp2nl
WBP2 N-terminal like
decreases expression
ISO
Malathion results in decreased expression of WBP2NL mRNA
CTD
PMID:37047231
NCBI chr15:82,183,126...82,198,848
Ensembl chr15:82,183,155...82,198,824
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Wfdc6a
WAP four-disulfide core domain 6A
decreases expression
ISO
Malathion results in decreased expression of WFDC6 mRNA
CTD
PMID:37047231
NCBI chr 2:164,421,439...164,427,704
Ensembl chr 2:164,421,439...164,427,367
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Wipf3
WAS/WASL interacting protein family, member 3
decreases expression
ISO
Malathion results in decreased expression of WIPF3 mRNA
CTD
PMID:37047231
NCBI chr 6:54,406,206...54,480,753
Ensembl chr 6:54,406,588...54,480,753
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Wt1
WT1 transcription factor
increases expression
ISO
Malathion results in increased expression of WT1 mRNA
CTD
PMID:32069766
NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
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Xkr4
X-linked Kx blood group related 4
decreases expression
ISO
Malathion results in decreased expression of XKR4 mRNA
CTD
PMID:37047231
NCBI chr 1:3,269,956...3,741,733
Ensembl chr 1:3,276,124...3,741,721
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Zfp42
zinc finger protein 42
decreases expression
ISO
Malathion results in decreased expression of ZFP42 mRNA
CTD
PMID:37047231
NCBI chr 8:43,748,100...43,760,041
Ensembl chr 8:43,748,100...43,760,017
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Zfpm2
zinc finger protein, multitype 2
increases expression
ISO
Malathion results in increased expression of ZFPM2 mRNA
CTD
PMID:37047231
NCBI chr15:40,518,438...40,967,988
Ensembl chr15:40,518,431...40,967,988
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Zscan5b
zinc finger and SCAN domain containing 5B
decreases expression
ISO
Malathion results in decreased expression of ZSCAN5B mRNA
CTD
PMID:37047231
NCBI chr 7:6,225,277...6,242,416
Ensembl chr 7:6,225,277...6,242,422
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