Annotation (Toggle Detail/Summary View) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | activation of MAPK activity | | IPI | UniProtKB:Q8BUE7 | 2290270 | MGI:MGI:3054501|PMID:15314156 | MGI | MGI:MGI:3054501 PMID:15314156 | adult behavior | | IMP | MGI:MGI:2450967 | 2290270 | MGI:MGI:2450013|PMID:12397180 | MGI | MGI:MGI:2450013 PMID:12397180 | brain development | | IMP | MGI:MGI:2450967 | 2290270 | MGI:MGI:2450013|PMID:12397180 | MGI | MGI:MGI:2450013 PMID:12397180 | branching morphogenesis of an epithelial tube | | ISO | UniProtKB:P08581 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 | glucose homeostasis | | IMP | MGI:MGI:2176227|MGI:MGI:3041135 | 2290270 | MGI:MGI:3584289|PMID:16049329 | MGI | MGI:MGI:3584289 PMID:16049329 | hepatocyte growth factor receptor signaling pathway | | IDA | | 2290270 | MGI:MGI:3054501|PMID:15314156 | MGI | MGI:MGI:3054501 PMID:15314156 | hepatocyte growth factor receptor signaling pathway | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | liver development | | IMP | MGI:MGI:1857655 | 2290270 | MGI:MGI:76093|PMID:7651534 | MGI | MGI:MGI:76093 PMID:7651534 | multicellular organismal development | | IEA | InterPro:IPR016201 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 | muscle cell migration | | IMP | MGI:MGI:1857655 | 2290270 | MGI:MGI:76093|PMID:7651534 | MGI | MGI:MGI:76093 PMID:7651534 | muscle organ development | | IGI | MGI:MGI:97487 | 2290270 | MGI:MGI:3505795|PMID:15376315 | MGI | MGI:MGI:3505795 PMID:15376315 | muscle organ development | | IMP | MGI:MGI:1858019 | 2290270 | MGI:MGI:3505795|PMID:15376315 | MGI | MGI:MGI:3505795 PMID:15376315 | myoblast proliferation | | IMP | MGI:MGI:1858021 | 2290270 | MGI:MGI:3618663|PMID:11061428 | MGI | MGI:MGI:3618663 PMID:11061428 | myotube differentiation | | IMP | MGI:MGI:1857655 | 2290270 | MGI:MGI:76093|PMID:7651534 | MGI | MGI:MGI:76093 PMID:7651534 | negative regulation of hydrogen peroxide-mediated programmed cell death | | ISO | UniProtKB:P08581 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 | negative regulation of peptidyl-threonine phosphorylation | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | negative regulation of transcription from RNA polymerase II promoter | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | neuron migration | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | phosphorylation | | IEA | UniProtKB-KW:KW-0418 | 2290270 | MGI:MGI:1354194 | UniProtKB | MGI:MGI:1354194 | placenta development | | IMP | MGI:MGI:1857655 | 2290270 | MGI:MGI:76093|PMID:7651534 | MGI | MGI:MGI:76093 PMID:7651534 | positive regulation of dendrite morphogenesis | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of DNA replication | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of gene expression | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of glucose transport | | IMP | MGI:MGI:2176227|MGI:MGI:3041135 | 2290270 | MGI:MGI:3584289|PMID:16049329 | MGI | MGI:MGI:3584289 PMID:16049329 | positive regulation of mitosis | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of neuron projection development | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of peptidyl-serine phosphorylation | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of peptidyl-threonine phosphorylation | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | positive regulation of transcription from RNA polymerase II promoter | | ISO | UniProtKB:P08581 | 2290270 | MGI:MGI:4834177 | MGI | MGI:MGI:4834177 | positive regulation of transcription from RNA polymerase II promoter | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | protein autophosphorylation | | IDA | | 2290270 | MGI:MGI:3054501|PMID:15314156 | MGI | MGI:MGI:3054501 PMID:15314156 | protein autophosphorylation | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | protein phosphorylation | | IEA | InterPro:IPR000719|InterPro:IPR001245|InterPro:IPR008266|InterPro:IPR020635|InterPro:IPR016244 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | | IMP | | 2290270 | MGI:MGI:2677549|PMID:14517989 | MGI | MGI:MGI:2677549 PMID:14517989 | regulation of excitatory postsynaptic membrane potential | | IMP | | 2290270 | MGI:MGI:4948152|PMID:21490227 | BHF-UCL | MGI:MGI:4948152 PMID:21490227 | regulation of synaptic transmission | | IMP | | 2290270 | MGI:MGI:4948152|PMID:21490227 | BHF-UCL | MGI:MGI:4948152 PMID:21490227 | skeletal muscle tissue development | | IMP | MGI:MGI:1857655 | 2290270 | MGI:MGI:76093|PMID:7651534 | MGI | MGI:MGI:76093 PMID:7651534 | sperm motility | | ISO | RGD:3082 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | transmembrane receptor protein tyrosine kinase signaling pathway | | IEA | InterPro:IPR016244 | 2290270 | MGI:MGI:2152098 | UniProtKB | MGI:MGI:2152098 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations
Phenotype Annotations
Disease Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | Adherens junction |
| Axon guidance | |
| Bacterial invasion of epithelial cells | |
| Cytokine-cytokine receptor interaction | |
| Endocytosis | |
| Focal adhesion | |
| Malaria | |
| Melanoma | |
| Pathways in cancer | |
| PI3K-Akt signaling pathway | |
| Proteoglycans in cancer | |
| Renal cell carcinoma | |
| Transcriptional misregulation in cancer | |
Phenotype Annotations
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Liu Y, etal., J Pathol. 2007 May;212(1):12-9. |
| 22. |
Lonngren U, etal., Brain Res Bull. 2006 Dec 11;71(1-3):208-18. Epub 2006 Oct 2. |
| 23. |
MGD and Homologene mouse data transfer |
| 24. |
MGD data from the GO Consortium |
| 25. |
MGD IEA |
| 26. |
Moon WS, etal., Cancer Res Treat. 2005 Jun;37(3):171-6. Epub 2005 Jun 30. |
| 27. |
Nakayama N, etal., Hepatology. 1996 Sep;24(3):596-602. |
| 28. |
Nakazawa K, etal., J Pathol. 2005 Jul;206(3):356-65. |
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| 31. |
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| 33. |
Park WS, etal., Cancer Res. 1999 Jan 15;59(2):307-10. |
| 34. |
Peghini PL, etal., Clin Cancer Res. 2002 Jul;8(7):2273-85. |
| 35. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 36. |
Rao UN, etal., Hum Pathol. 1997 Sep;28(9):1066-70. |
| 37. |
RGD automated import pipeline |
| 38. |
Rong S, etal., Cancer Res. 1993 Nov 15;53(22):5355-60. |
| 39. |
Salazar-Montes A, etal., World J Gastroenterol. 2006 Oct 7;12(37):5995-6001. |
| 40. |
Sanders HR and Albitar M, Cancer Genet Cytogenet. 2010 Nov;203(1):7-15. |
| 41. |
Schmidt L, etal., Nat Genet. 1997 May;16(1):68-73. |
| 42. |
Towner RA, etal., J Cell Mol Med. 2008 Jan-Feb;12(1):174-86. Epub 2007 Jan 9. |
| 43. |
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| 44. |
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| 45. |
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| 46. |
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| 47. |
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| 48. |
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| 49. |
Yoshida T, etal., Biochem Pharmacol. 2010 Sep 1;80(5):613-23. Epub 2010 May 24. |
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RGD Disease Portals| Met has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Met (Mus musculus) |
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| Met (Rattus norvegicus) |
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Position Markers| PMC151835P1 |
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| D6Mit157 |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_008591 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AAHY01051745 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHY01051746 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AC024950 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AE017189 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK145182 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK148258 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK170560 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558815 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558816 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558817 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558818 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558819 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY558820 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC117969 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC117970 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC128481 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC128482 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BU514228 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466533 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CJ131939 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CK332973 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CK625647 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CX563675 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M33424 | (Get FASTA) | Search GEO for Microarray Profiles | |
| Y00671 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_008591 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_032617 | |||||||||||||||||||||||||
| Peptide Label: | precursor | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_032617 | (Get FASTA) |
| GenBank Protein | AAA40015 | (Get FASTA) |
| AAI17970 | (Get FASTA) | |
| AAI17971 | (Get FASTA) | |
| AAI28482 | (Get FASTA) | |
| AAI28483 | (Get FASTA) | |
| AAI56288 | (Get FASTA) | |
| AAR16291 | (Get FASTA) | |
| AAS66880 | (Get FASTA) | |
| AAS66881 | (Get FASTA) | |
| AAS66882 | (Get FASTA) | |
| AAS66883 | (Get FASTA) | |
| BAE41881 | (Get FASTA) | |
| CAA68680 | (Get FASTA) | |
| EDL13881 | (Get FASTA) | |
| P16056 | (Get FASTA) |
Promoters| RGD ID: | 6839614 | ||||||||||
| Promoter ID: | MM_KWN:45222 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Liver | ||||||||||
| Transcripts: | ENSMUST00000080469 | ||||||||||
| Position: |
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| RGD ID: | 6839615 | ||||||||||
| Promoter ID: | MM_KWN:45224 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Liver | ||||||||||
| Transcripts: | OTTMUST00000058745 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000009376 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000111103 | ENTREZGENE |
| Ensembl Transcript | ENSMUST00000115443 | ENTREZGENE |
| Entrez Gene | 17295 | ENTREZGENE |
| Gene3D-CATH | Ig-like_fold | UniProtKB/Swiss-Prot |
| WD40/YVTN_repeat-like | UniProtKB/Swiss-Prot | |
| Germonline | ENSMUSG00000009376 | |
| HomoloGene Group ID | 206 | ENTREZGENE |
| InterPro | Ig-like_fold | UniProtKB/Swiss-Prot |
| Ig_E-set | UniProtKB/Swiss-Prot | |
| IPT_TIG_rcpt | UniProtKB/Swiss-Prot | |
| Kinase-like_dom | UniProtKB/Swiss-Prot | |
| Plexin-like | UniProtKB/Swiss-Prot | |
| Plexin-like_fold | UniProtKB/Swiss-Prot | |
| Plexin_repeat | UniProtKB/Swiss-Prot | |
| Prot_kinase_cat_dom | UniProtKB/Swiss-Prot | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot | |
| Semaphorin/CD100_Ag | UniProtKB/Swiss-Prot | |
| Ser-Thr/Tyr_kinase | UniProtKB/Swiss-Prot | |
| Tyr_kinase_AS | UniProtKB/Swiss-Prot | |
| Tyr_kinase_cat_dom | UniProtKB/Swiss-Prot | |
| Tyr_kinase_HGF/MSP_rcpt | UniProtKB/Swiss-Prot | |
| WD40/YVTN_repeat-like_dom | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:17295 | ENTREZGENE, UniProtKB/TrEMBL |
| MGD | MGI:96969 | ENTREZGENE |
| Pfam | Pkinase_Tyr | UniProtKB/Swiss-Prot |
| PSI | UniProtKB/Swiss-Prot | |
| Sema | UniProtKB/Swiss-Prot | |
| TIG | UniProtKB/Swiss-Prot | |
| PharmGKB | MET | RGD |
| PIRSF | TyrPK_HGF-R | UniProtKB/Swiss-Prot |
| PRINTS | TYRKINASE | UniProtKB/Swiss-Prot |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_TYR | UniProtKB/Swiss-Prot | |
| SEMA | UniProtKB/Swiss-Prot | |
| SMART | IPT | UniProtKB/Swiss-Prot |
| PSI | UniProtKB/Swiss-Prot | |
| Sema | UniProtKB/Swiss-Prot | |
| TyrKc | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | Ig_E-set | UniProtKB/Swiss-Prot |
| Kinase_like | UniProtKB/Swiss-Prot | |
| Plexin-like_fold | UniProtKB/Swiss-Prot | |
| Sema | UniProtKB/Swiss-Prot | |
| UniGene | Mm.86844 | ENTREZGENE |
| UniProt | A1A597_MOUSE | UniProtKB/TrEMBL |
| A2VCS0_MOUSE | UniProtKB/TrEMBL | |
| A4FUV6_MOUSE | UniProtKB/TrEMBL | |
| A4FUV7_MOUSE | UniProtKB/TrEMBL | |
| D3YVY2_MOUSE | UniProtKB/TrEMBL | |
| F6RCC5_MOUSE | UniProtKB/TrEMBL | |
| F6X333_MOUSE | UniProtKB/TrEMBL | |
| F8VQL0_MOUSE | UniProtKB/TrEMBL | |
| MET_MOUSE | UniProtKB/Swiss-Prot | |
| Q3TCS4_MOUSE | UniProtKB/TrEMBL |
| More on Met | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 10894 |
| Created: | 2000-05-25 |
| Species: | Mus musculus |
| Last Modified: | 2013-06-04 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




