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Gene-Chemical Interaction AnnotationsGene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ammonium chloride | affects expression | ISO | RGD:3351 | 6480464 | Ammonium Chloride affects the expression of PLIN1 mRNA | CTD | PMID:16483693 | ammonium chloride | decreases degradation | EXP | | 6480464 | Ammonium Chloride results in decreased degradation of PLIN1 protein | CTD | PMID:17488708 | ammonium chloride | multiple interactions | EXP | | 6480464 | Ammonium Chloride inhibits the reaction [Nelfinavir results in increased degradation of PLIN1 protein] | CTD | PMID:17488708 | dexamethasone | decreases expression | ISO | RGD:3351 | 6480464 | Dexamethasone results in decreased expression of PLIN1 mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | ISO | RGD:3351 | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of PLIN1 mRNA] | CTD | PMID:20032058 | disodium selenite | increases expression | ISO | RGD:733482 | 6480464 | Sodium Selenite results in increased expression of PLIN1 mRNA | CTD | PMID:18175754 | rosiglitazone | affects response to substance | ISO | RGD:733482 | 6480464 | PLIN1 gene polymorphism affects the susceptibility to rosiglitazone | CTD | PMID:16732015 | rosiglitazone | increases expression | ISO | RGD:3351 | 6480464 | rosiglitazone results in increased expression of PLIN1 mRNA | CTD | PMID:21515302 | testosterone | multiple interactions | ISO | RGD:3351 | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of PLIN1 mRNA] | CTD | PMID:20032058 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations| External Database Links | |
| KEGG Pathway | PPAR signaling pathway |
Phenotype AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | PPAR signaling pathway |
Phenotype AnnotationsReferences - curated| 1. |
Corella D, etal., J Clin Endocrinol Metab. 2005 Sep;90(9):5121-6. Epub 2005 Jun 28. |
| 2. |
Forcheron F, etal., Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1711-7. Epub 2005 Jun 16. |
| 3. |
MGD and Homologene mouse data transfer |
| 4. |
MGD data from the GO Consortium |
| 5. |
Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73. |
| 6. |
RGD automated import pipeline |
| 7. |
RGD automated import pipeline for gene-chemical interactions |
| 8. |
Tansey JT, etal., Proc Natl Acad Sci U S A 2001 May 22;98(11):6494-9. |
| 9. |
Yamaguchi T, etal., J Biol Chem 2004 Jul 16;279(29):30490-7. Epub 2004 May 10. |
References - uncurated| PubMed | 10349636 |
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| 11076861 | |
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| 11217851 | |
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| 20091459 | |
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| 21944269 | |
| 21983901 | |
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RGD Disease Portals| Plin1 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Plin1 (Mus musculus) |
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| PLIN1 (Homo sapiens) |
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| Plin1 (Rattus norvegicus) |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001113471 | (Get FASTA) | Search GEO for Microarray Profiles |
| NM_175640 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHY01063462 | (Get FASTA) | Search GEO for Microarray Profiles |
| AC158582 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK027962 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK031445 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AY161165 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC025137 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC037748 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC096685 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BY723040 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466543 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CJ060785 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_175640 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_783571 | |||||||||||||||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001113471 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_001106942 | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001106942 | (Get FASTA) |
| NP_783571 | (Get FASTA) | |
| GenBank Protein | AAH96685 | (Get FASTA) |
| AAN77870 | (Get FASTA) | |
| BAC27409 | (Get FASTA) | |
| EDL07050 | (Get FASTA) | |
| EDL07051 | (Get FASTA) | |
| EDL07052 | (Get FASTA) | |
| EDL07053 | (Get FASTA) | |
| EDL07054 | (Get FASTA) | |
| EDL07055 | (Get FASTA) | |
| Q8CGN5 | (Get FASTA) |
Promoters| RGD ID: | 6841781 | ||||||||||
| Promoter ID: | MM_KWN:51250 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6 | ||||||||||
| Transcripts: | UC009HYW.1 | ||||||||||
| Position: |
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| RGD ID: | 6841782 | ||||||||||
| Promoter ID: | MM_KWN:51251 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6 | ||||||||||
| Transcripts: | UC009HYU.1 | ||||||||||
| Position: |
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| RGD ID: | 6841783 | ||||||||||
| Promoter ID: | MM_KWN:51252 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | 3T3L1_Day4 | ||||||||||
| Transcripts: | NM_175640, UC009HYV.1, UC009HYX.1 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000030546 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000032762 | ENTREZGENE |
| ENSMUSP00000136996 | ENTREZGENE | |
| Ensembl Transcript | ENSMUST00000032762 | ENTREZGENE |
| ENSMUST00000178257 | ENTREZGENE | |
| Entrez Gene | 103968 | ENTREZGENE |
| Germonline | ENSMUSG00000030546 | |
| HomoloGene Group ID | 2001 | ENTREZGENE |
| InterPro | Perilipin | UniProtKB/Swiss-Prot |
| IPI | IPI00223783 | UniProtKB/Swiss-Prot |
| IPI00947590 | UniProtKB/Swiss-Prot | |
| IPI00947605 | UniProtKB/Swiss-Prot | |
| IPI00947617 | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:103968 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:1890505 | ENTREZGENE |
| PANTHER | Perilipin | UniProtKB/Swiss-Prot |
| Pfam | Perilipin | UniProtKB/Swiss-Prot |
| PIRSF | PAT | UniProtKB/Swiss-Prot |
| UniGene | Mm.254917 | ENTREZGENE |
| UniProt | PLIN1_MOUSE | UniProtKB/Swiss-Prot |
| More on Plin1 | |
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Entrez Gene |
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Ensembl Gene |
| Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 736220 |
| Created: | 2004-02-06 |
| Species: | Mus musculus |
| Last Modified: | 2013-02-27 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.