Zfpm2 (zinc finger protein, multitype 2) - Rat Genome Database

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Gene: Zfpm2 (zinc finger protein, multitype 2) Mus musculus
Analyze
Symbol: Zfpm2
Name: zinc finger protein, multitype 2
RGD ID: 1550372
MGI Page MGI
Description: Enables transcription corepressor activity. Involved in several processes, including negative regulation of female gonad development; positive regulation of cardiac muscle cell proliferation; and positive regulation of male gonad development. Acts upstream of or within several processes, including circulatory system development; in utero embryonic development; and regulation of transcription by RNA polymerase II. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; gut; and heart and pericardium. Used to study congenital diaphragmatic hernia; tetralogy of Fallot; and tricuspid atresia. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; congenital diaphragmatic hernia; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B330005D23Rik; FOG; FOG-; FOG-2; FOG2; Friend of GATA 2; friend of GATA protein 2; friend of GATA-1 2; friend of GATA-2; mFOG-2; zinc finger protein multitype 2; zinc finger protein ZFPM2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391540,518,438 - 40,967,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)EnsemblGRCm39 Ensembl
GRCm381540,655,042 - 41,104,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371540,486,588 - 40,936,138 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361540,485,116 - 40,934,666 (+)NCBIMGSCv36mm8
Celera1541,140,194 - 41,582,164 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
male germ cell nucleus  (IDA)
nucleoplasm  (ISO,TAS)
nucleus  (IBA,IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aortic valve morphology  (IAGP)
abnormal atrioventricular cushion morphology  (IAGP)
abnormal cardiac epithelial to mesenchymal transition  (IAGP)
abnormal cardiovascular development  (IAGP)
abnormal coronary circulation  (IAGP)
abnormal coronary vessel morphology  (IAGP)
abnormal diaphragm morphology  (IAGP)
abnormal heart atrium morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart echocardiography feature  (IAGP)
abnormal heart left ventricle wall thickness  (IAGP)
abnormal heart right ventricle morphology  (IAGP)
abnormal heart valve morphology  (IAGP)
abnormal heart ventricle morphology  (IAGP)
abnormal heart ventricle outflow tract morphology  (IAGP)
abnormal involution of the mammary gland  (IAGP)
abnormal Leydig cell differentiation  (IAGP)
abnormal lung development  (IAGP)
abnormal mammary gland morphology  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal myocardium compact layer morphology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal primary sex determination  (IAGP)
abnormal pulmonary valve morphology  (IAGP)
abnormal right lung middle lobe morphology  (IAGP)
abnormal Sertoli cell morphology  (IAGP)
absent coronary vessels  (IAGP)
absent right lung accessory lobe  (IAGP)
atrial septal defect  (IAGP)
cardiac fibrosis  (IAGP)
common atrioventricular valve  (IAGP)
complete atrioventricular septal defect  (IAGP)
congestive heart failure  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased heart rate  (IAGP)
decreased ventricle muscle contractility  (IAGP)
dilated heart  (IAGP)
dilated heart atrium  (IAGP)
dilated heart ventricle  (IAGP)
double outlet right ventricle  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
globular heart  (IAGP)
heart right ventricle outflow tract stenosis  (IAGP)
hemorrhage  (IAGP)
hydrops fetalis  (IAGP)
increased atrioventricular cushion size  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased heart atrium size  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ostium primum atrial septal defect  (IAGP)
overriding aortic valve  (IAGP)
ovotestis  (IAGP)
pallor  (IAGP)
pericardial edema  (IAGP)
pericardial effusion  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
primary sex reversal  (IAGP)
pulmonary hypoplasia  (IAGP)
pulmonary valve hyperplasia  (IAGP)
skin edema  (IAGP)
small liver  (IAGP)
supravalvar pulmonary trunk stenosis  (IAGP)
thick pulmonary valve  (IAGP)
thin diaphragm muscle  (IAGP)
thin left ventricle myocardium compact layer  (IAGP)
thin myocardium  (IAGP)
thin myocardium compact layer  (IAGP)
thin ventricle myocardium compact layer  (IAGP)
thin ventricular wall  (IAGP)
tricuspid valve atresia  (IAGP)
true hermaphroditism  (IAGP)
ventricular myocardium compact layer hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. AML1-FOG2 fusion protein in myelodysplasia. Chan EM, etal., Blood. 2005 Jun 1;105(11):4523-6. Epub 2005 Feb 10.
2. FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Garnatz AS, etal., Dev Biol. 2014 Nov 1;395(1):50-61. doi: 10.1016/j.ydbio.2014.08.030. Epub 2014 Sep 6.
3. Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. Klarin D, etal., Circ Cardiovasc Genet. 2017 Apr;10(2):e001643. doi: 10.1161/CIRCGENETICS.116.001643.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Pizzuti A, etal., Hum Mutat. 2003 Nov;22(5):372-7.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription. Rouf R, etal., Circ Res. 2008 Aug 29;103(5):493-501. doi: 10.1161/CIRCRESAHA.108.181487. Epub 2008 Jul 25.
13. CpG island shore methylation of ZFPM2 is identified in tetralogy of fallot samples. Sheng W, etal., Pediatr Res. 2016 Jul;80(1):151-8. doi: 10.1038/pr.2016.42. Epub 2016 Mar 9.
14. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Svensson EC, etal., Nat Genet. 2000 Jul;25(3):353-6. doi: 10.1038/77146.
Additional References at PubMed
PMID:8889548   PMID:9927674   PMID:9927675   PMID:10225993   PMID:10329627   PMID:10330188   PMID:10349636   PMID:10801815   PMID:10892744   PMID:10999851   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11238910   PMID:11297508   PMID:11382775   PMID:12213678   PMID:12223418   PMID:12477932   PMID:12606287   PMID:12606418   PMID:14551244   PMID:14614148   PMID:14648841  
PMID:15489334   PMID:15507435   PMID:15533830   PMID:15618518   PMID:15766748   PMID:16103912   PMID:16127717   PMID:16141072   PMID:16141073   PMID:16251273   PMID:16602821   PMID:16919269  
PMID:17069789   PMID:17142311   PMID:17274974   PMID:17303760   PMID:17310981   PMID:17445768   PMID:17540364   PMID:17848526   PMID:18023262   PMID:18287559   PMID:18577233   PMID:18840685  
PMID:18927154   PMID:19301398   PMID:19325248   PMID:19411759   PMID:19578715   PMID:19582148   PMID:19842175   PMID:19877281   PMID:19884258   PMID:20059953   PMID:20106871   PMID:20299672  
PMID:20356956   PMID:20619341   PMID:20705609   PMID:21267068   PMID:21385577   PMID:21795542   PMID:21873635   PMID:22031906   PMID:22267003   PMID:22284184   PMID:22315423   PMID:22678282  
PMID:22932696   PMID:23095882   PMID:23226341   PMID:23283686   PMID:23395374   PMID:23523356   PMID:23769843   PMID:23788640   PMID:23797856   PMID:23836893   PMID:23987514   PMID:24415953  
PMID:24930700   PMID:24952961   PMID:25037921   PMID:25079229   PMID:25497097   PMID:25641781   PMID:26182416   PMID:26285119   PMID:26718003   PMID:27117402   PMID:27207553   PMID:27210758  
PMID:27320921   PMID:27321927   PMID:27576955   PMID:28195173   PMID:28302382   PMID:28346476   PMID:29262331   PMID:31012180   PMID:32325033   PMID:33046550   PMID:33053343   PMID:34161768  
PMID:34321999   PMID:35084365   PMID:35613274   PMID:35815619   PMID:35930666   PMID:37561632   PMID:38189150  


Genomics

Comparative Map Data
Zfpm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391540,518,438 - 40,967,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)EnsemblGRCm39 Ensembl
GRCm381540,655,042 - 41,104,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv371540,486,588 - 40,936,138 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361540,485,116 - 40,934,666 (+)NCBIMGSCv36mm8
Celera1541,140,194 - 41,582,164 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.74NCBI
ZFPM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388105,318,438 - 105,804,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8104,590,733 - 105,804,539 (+)EnsemblGRCh38hg38GRCh38
GRCh378106,330,666 - 106,816,767 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368106,400,323 - 106,885,943 (+)NCBINCBI36Build 36hg18NCBI36
Build 348106,400,322 - 106,885,941NCBI
Celera8102,518,281 - 103,003,726 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8101,532,803 - 102,138,045 (+)NCBIHuRef
CHM1_18106,371,762 - 106,857,264 (+)NCBICHM1_1
T2T-CHM13v2.08106,445,857 - 106,932,108 (+)NCBIT2T-CHM13v2.0
Zfpm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8773,563,732 - 74,001,041 (+)NCBIGRCr8
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx773,563,335 - 73,995,149 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0775,765,841 - 76,197,677 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0775,633,940 - 76,065,769 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Celera768,728,223 - 69,158,299 (+)NCBICelera
Cytogenetic Map7q31NCBI
Zfpm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541728,920,210 - 29,269,271 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541728,931,428 - 29,268,778 (+)NCBIChiLan1.0ChiLan1.0
ZFPM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27122,596,111 - 123,154,098 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1898,118,921 - 98,676,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08101,872,850 - 102,430,622 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18104,193,343 - 104,577,698 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8104,023,062 - 104,576,688 (+)Ensemblpanpan1.1panPan2
ZFPM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1136,435,368 - 6,796,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl136,336,794 - 6,796,322 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha136,442,921 - 6,803,153 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0136,588,050 - 7,045,717 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl136,587,518 - 7,044,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1136,451,443 - 6,811,875 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0136,571,226 - 6,931,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0136,646,836 - 7,007,257 (+)NCBIUU_Cfam_GSD_1.0
Zfpm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530331,006,795 - 31,431,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647038,432,897 - 38,857,662 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647038,432,894 - 38,857,656 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFPM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl431,606,773 - 32,094,287 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1431,607,968 - 31,996,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2434,232,973 - 34,242,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2434,441,657 - 34,641,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFPM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18100,138,867 - 100,620,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfpm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476321,388,244 - 21,707,953 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476321,388,060 - 21,708,969 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfpm2
13530 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:330
Count of miRNA genes:209
Interacting mature miRNAs:254
Transcripts:ENSMUST00000053467
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
10412172Habiir5_mhyperoxic acute lung injury imprinted region 5 (mouse)Not determined15927302243311880Mouse
4140994Shali3_msurvival time to hyperoxic acute lung injury 3 (mouse)Not determined927302243311880Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384700647847148Mouse
1302165Yv_myellow value (mouse)Not determined151384700647847148Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492758748927756Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492758748927756Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492758748927756Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564534349645470Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603395450033954Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060008650763396Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
12792977Tbmd1_mtibial bone mineral density 1, males only (mouse)153807048952031841Mouse
13801028Toa2_mtesticular oocyte appearance 2 (mouse)153874784643035791Mouse
1301580Hrq2_mheart rate quantitative locus 2 (mouse)Not determined153910039573100593Mouse
1300949Lore5_mloss of righting induced by ethanol 5 (mouse)Not determined154001944158022297Mouse
4142459Lfnq3_mlung function QTL 3 (mouse)Not determined4017702272372580Mouse

Markers in Region
Zfpm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371540,935,637 - 40,935,716UniSTSGRCm37
Celera1541,581,663 - 41,581,742UniSTS
Cytogenetic Map15CUniSTS
cM Map15 UniSTS
cM Map1519.3UniSTS
Mbtd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381540,670,414 - 40,671,102UniSTSGRCm38
MGSCv371540,501,960 - 40,502,648UniSTSGRCm37
Celera1541,155,508 - 41,156,196UniSTS
Cytogenetic Map15CUniSTS
Cytogenetic Map11DUniSTS
cM Map11 UniSTS
06.MMHAP86FLB3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381540,739,747 - 40,739,990UniSTSGRCm38
MGSCv371540,571,293 - 40,571,536UniSTSGRCm37
Celera1541,224,768 - 41,225,011UniSTS
Cytogenetic Map15CUniSTS
cM Map1519.3UniSTS
Whitehead_YAC15 UniSTS
PMC303372P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381541,103,796 - 41,104,276UniSTSGRCm38
MGSCv371540,935,342 - 40,935,822UniSTSGRCm37
Celera1541,581,368 - 41,581,848UniSTS
Cytogenetic Map15CUniSTS
cM Map1519.3UniSTS
Zfpm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15CUniSTS
cM Map15 UniSTS
Zfpm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381541,104,091 - 41,104,170UniSTSGRCm38
MGSCv371540,935,637 - 40,935,716UniSTSGRCm37
Celera1541,581,663 - 41,581,742UniSTS
Cytogenetic Map15CUniSTS
Zfpm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15CUniSTS
Zfpm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15CUniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000053467   ⟹   ENSMUSP00000051335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)Ensembl
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229777
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1540,518,431 - 40,736,119 (+)Ensembl
GRCm38.p6 Ensembl1540,655,035 - 40,872,723 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230319   ⟹   ENSMUSP00000155094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1540,528,386 - 40,967,982 (+)Ensembl
GRCm38.p6 Ensembl1540,664,990 - 41,104,586 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230723
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1540,518,747 - 40,638,655 (+)Ensembl
GRCm38.p6 Ensembl1540,655,351 - 40,775,259 (+)Ensembl
RefSeq Acc Id: NM_001356998   ⟹   NP_001343927
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391540,518,438 - 40,967,988 (+)NCBI
GRCm381540,655,042 - 41,104,592 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011766   ⟹   NP_035896
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391540,518,438 - 40,967,988 (+)NCBI
GRCm381540,655,042 - 41,104,592 (+)NCBI
MGSCv371540,486,588 - 40,936,138 (+)RGD
Celera1541,140,194 - 41,582,164 (+)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035896   ⟸   NM_011766
- Peptide Label: isoform 1
- UniProtKB: Q9Z0F2 (UniProtKB/Swiss-Prot),   Q8CCH7 (UniProtKB/Swiss-Prot),   A5HE91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001343927   ⟸   NM_001356998
- Peptide Label: isoform 2
- UniProtKB: A5HE91 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000051335   ⟸   ENSMUST00000053467
RefSeq Acc Id: ENSMUSP00000155094   ⟸   ENSMUST00000230319
Protein Domains
C2H2-type   CCHC FOG-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CCH7-F1-model_v2 AlphaFold Q8CCH7 1-1151 view protein structure

Promoters
RGD ID:6826031
Promoter ID:MM_KWN:18346
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   MEF_B4
Transcripts:ENSMUST00000110303,   NM_011766,   UC007VOQ.1,   UC007VOR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361540,486,214 - 40,486,714 (+)MPROMDB
RGD ID:8683656
Promoter ID:EPDNEW_M19858
Type:initiation region
Name:Zfpm2_1
Description:Mus musculus zinc finger protein, multitype 2 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381540,655,035 - 40,655,095EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1334444 AgrOrtholog
Ensembl Genes ENSMUSG00000022306 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000053467 ENTREZGENE
  ENSMUST00000053467.6 UniProtKB/Swiss-Prot
  ENSMUST00000230319 ENTREZGENE
  ENSMUST00000230319.2 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_CCHC_FOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZFPM1/2_PR UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22762 UniProtKB/Swiss-Prot
MGD MGI:1334444 ENTREZGENE
NCBI Gene 22762 ENTREZGENE
PANTHER PTHR12958 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZFPM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FOG1-like_PR UniProtKB/Swiss-Prot
  zf-met UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Zfpm2 PhenoGen
PROSITE ZF_CCHC_FOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A5HE91 ENTREZGENE, UniProtKB/TrEMBL
  FOG2_MOUSE UniProtKB/Swiss-Prot
  Q3UXX7_MOUSE UniProtKB/TrEMBL
  Q8CCH7 ENTREZGENE
  Q9Z0F2 ENTREZGENE
UniProt Secondary Q9Z0F2 UniProtKB/Swiss-Prot