Gene: Tjp2 (tight junction protein 2) Mus musculus
Symbol: Tjp2
Name: tight junction protein 2
Description: ENCODES a protein that exhibits cadherin binding (ortholog); protein binding, bridging (ortholog); protein C-terminus binding (ortholog); INVOLVED IN negative regulation of osteoclast development; TNFSF11-mediated signaling pathway; establishment of endothelial intestinal barrier (ortholog); ASSOCIATED WITH abnormal plasma membrane morphology; absent mesoderm; decreased cell proliferation; ASSOCIATED WITH Bile Acid Synthesis Defect, Congenital, 1 (ortholog); Cholestasis, Intrahepatic (ortholog); Deafness, Autosomal Dominant 51 (ortholog); FOUND IN cell junction; cell-cell junction; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 3,4-methylenedioxymethamphetamine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: tight junction protein ZO-2; Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2); ZO-2; zona occludens protein 2; zonula occludens protein 2
Homo sapiens (human) : TJP2 (tight junction protein 2)  HGNC
Rattus norvegicus (Norway rat) : Tjp2 (tight junction protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TJP2 (tight junction protein 2)
Canis lupus familiaris (dog) : TJP2 (tight junction protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tjp2 (tight junction protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381924,094,502 - 24,225,130 (-)NCBIGRCm38mm10GRCm38
MGSCv371924,168,992 - 24,299,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv361924,161,608 - 24,241,085 (-)NCBImm8
Celera1924,858,437 - 24,990,744 (-)NCBI
Cytogenetic Map19 BNCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tjp2
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 733147
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2017-04-11
Status: ACTIVE