Gene: Tjp2 (tight junction protein 2) Mus musculus
Symbol: Tjp2
Name: tight junction protein 2
Description: ENCODES a protein that exhibits protein binding, bridging (ortholog); protein C-terminus binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of osteoclast development; TNFSF11-mediated signaling pathway; establishment of endothelial intestinal barrier (ortholog); ASSOCIATED WITH abnormal plasma membrane morphology; absent mesoderm; decreased cell proliferation; ASSOCIATED WITH Hypercholanemia, Familial (ortholog); Hypertension (ortholog); Metabolic Diseases (ortholog); FOUND IN cell junction; nucleus; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 3,4-methylenedioxymethamphetamine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: tight junction protein ZO-2; Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2); ZO-2; zona occludens protein 2; zonula occludens protein 2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381924,094,502 - 24,225,128 (-)NCBIGRCm38mm10GRCm38
MGSCv371924,168,992 - 24,299,444 (-)NCBIGRCm37mm9NCBIm37
MGSCv361924,161,608 - 24,241,085 (-)NCBImm8
Celera1924,858,437 - 24,990,744 (-)NCBI
Cytogenetic Map19 C1NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tjp2
Entrez Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733147
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2016-06-07
Status: ACTIVE