dibenzo[a,l]pyrene - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	dibenzo[a,l]pyrene	go back to main search page
Accession:	CHEBI:35861	browse the term
Definition:	An ortho- and peri-fused polycyclic arene that has formula C24H14.
Synonyms:	exact_synonym:	naphtho[1,2,3,4-pqr]tetraphene
	related_synonym:	1,2,3,4-Dibenzpyrene; 1,2,9,10-Dibenzopyrene; 1,2:3,4-Dibenzopyrene; 2,3:4,5-Dibenzopyrene; 4,5,6,7-Dibenzpyrene; DBP; Db(a,l)p; Dibenzo(d,e,f,p)chrysene; Dibenzo[def,p]chrysene; Formula=C24H14; InChI=1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H; InChIKey=JNTHRSHGARDABO-UHFFFAOYSA-N; SMILES=c1ccc2c(c1)cc1ccc3cccc4c5ccccc5c2c1c34
	xref:	Beilstein:2054068; CAS:191-30-0; KEGG:C19174
	xref_mesh:	MESH:C041517

show annotations for term's descendants Sort by:
Rat (357) Mouse (364) Human (365) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (365)

dibenzo[a,l]pyrene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of A2M mRNA

NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229

G

ATP binding cassette subfamily B member 1

increases expression

dibenzo(a,l)pyrene results in increased expression of ABCB1 mRNA

NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323

G

ATP binding cassette subfamily C member 1 (ABCC1 blood group)

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ABCC1 mRNA

NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257

G

ATP binding cassette subfamily D member 3

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of ABCD3 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ABCD3 mRNA

NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666

G

ABRA C-terminal like

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ABRACL mRNA

NCBI chr 6:139,028,745...139,043,302
Ensembl chr 6:139,028,745...139,043,302

G

acyl-CoA oxidase 2

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of ACOX2 mRNA

NCBI chr 3:58,505,136...58,537,190
Ensembl chr 3:58,505,136...58,537,283

G

actin beta

increases expression
decreases expression

dibenzo(a,l)pyrene results in increased expression of ACTB protein
dibenzo(a,l)pyrene results in decreased expression of ACTB mRNA

PMID:18495319 PMID:31255691

NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902

G

AHNAK nucleoprotein

increases expression

dibenzo(a,l)pyrene results in increased expression of AHNAK mRNA

NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235

G

aryl hydrocarbon receptor

increases response to substance
multiple interactions
affects response to substance

AHR protein results in increased susceptibility to dibenzo(a,l)pyrene
dibenzo(a,l)pyrene binds to and results in increased activity of AHR protein
AHR affects the susceptibility to dibenzo(a,l)pyrene

PMID:11525907 PMID:12117779 PMID:15352028

NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152

G

aryl hydrocarbon receptor repressor

increases expression

dibenzo(a,l)pyrene results in increased expression of AHRR mRNA

NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291

G

A-kinase anchoring protein 13

increases expression

dibenzo(a,l)pyrene results in increased expression of AKAP13 mRNA

NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358

G

aldo-keto reductase family 1 member B

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of AKR1B1 mRNA

NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284

G

aldo-keto reductase family 1 member B10

decreases expression

dibenzo(a,l)pyrene results in decreased expression of AKR1B10 mRNA

NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412

G

aldo-keto reductase family 1 member C1

multiple interactions

[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C1 mRNA; [Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C1 mRNA

NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283

G

aldo-keto reductase family 1 member C2

multiple interactions

[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA; [Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA

NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031

G

aldo-keto reductase family 1 member C3

multiple interactions

[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA; [Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C3 mRNA

NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686

G

aldehyde dehydrogenase 1 family member A3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ALDH1A3 mRNA

NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,877,714...100,916,626

G

aldehyde dehydrogenase 3 family member A1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ALDH3A1 mRNA

PMID:31255691 PMID:32890658

NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943

G

aldolase, fructose-bisphosphate B

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ALDOB mRNA

NCBI chr 9:101,420,560...101,435,774
Ensembl chr 9:101,420,560...101,449,664

G

ALG5 dolichyl-phosphate beta-glucosyltransferase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ALG5 mRNA

NCBI chr13:36,949,738...36,999,367
Ensembl chr13:36,949,738...37,000,763

G

alpha-methylacyl-CoA racemase

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of AMACR mRNA

NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104

G

ankyrin repeat domain 12

increases expression

dibenzo(a,l)pyrene results in increased expression of ANKRD12 mRNA

NCBI chr18:9,136,781...9,285,985
Ensembl chr18:9,136,228...9,285,985

G

ankyrin repeat domain 17

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ANKRD17 mRNA

NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798

G

apolipoprotein C3

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of APOC3 mRNA

NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072

G

ADP ribosylation factor GTPase activating protein 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ARFGAP1 mRNA

NCBI chr20:63,272,813...63,289,790
Ensembl chr20:63,272,785...63,289,790

G

Rho GTPase activating protein 17

increases expression

dibenzo(a,l)pyrene results in increased expression of ARHGAP17 mRNA

NCBI chr16:24,919,389...25,015,369
Ensembl chr16:24,919,389...25,015,666

G

arrestin domain containing 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ARRDC4 mRNA

NCBI chr15:97,960,703...97,973,833
Ensembl chr15:97,960,703...97,973,833

G

ATPase family AAA domain containing 2B

increases expression

dibenzo(a,l)pyrene results in increased expression of ATAD2B mRNA

NCBI chr 2:23,677,969...23,927,123
Ensembl chr 2:23,748,664...23,927,123

G

activating transcription factor 3

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of ATF3 mRNA

NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777

G

ATPase Na+/K+ transporting subunit beta 1

increases expression

dibenzo(a,l)pyrene results in increased expression of ATP1B1 mRNA

NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992

G

ATP synthase F1 subunit alpha

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ATP5F1A protein

NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334

G

ATP synthase membrane subunit k

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ATP5MK mRNA

NCBI chr10:103,389,050...103,396,475
Ensembl chr10:103,389,041...103,396,492

G

axin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of AXIN1 mRNA

NCBI chr16:287,440...352,723
Ensembl chr16:287,440...352,723

G

BTG3 associated nuclear protein

increases expression

dibenzo(a,l)pyrene results in increased expression of BANP mRNA

NCBI chr16:87,949,238...88,077,318
Ensembl chr16:87,949,244...88,077,318

G

BCL2 binding component 3

multiple interactions
affects expression
increases expression

2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]; Estradiol inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]
dibenzo(a,l)pyrene results in increased expression of BBC3 mRNA

PMID:24954032 PMID:26496743

NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766

G

B cell receptor associated protein 29

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BCAP29 mRNA

NCBI chr 7:107,580,007...107,623,317
Ensembl chr 7:107,580,246...107,629,170

G

BCL2 like 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BCL2L1 mRNA

NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989

G

BCL2 like 11

increases methylation

dibenzo(a,l)pyrene results in increased methylation of BCL2L11 gene

NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444

G

BCL2 like 15

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BCL2L15 mRNA

PMID:23274566 PMID:25908611

NCBI chr 1:113,876,816...113,887,581
Ensembl chr 1:113,876,816...113,887,581

G

baculoviral IAP repeat containing 5

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BIRC5 mRNA

NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636

G

bone morphogenetic protein 1

decreases methylation

dibenzo(a,l)pyrene results in decreased methylation of BMP1 promoter

NCBI chr 8:22,165,372...22,212,326
Ensembl chr 8:22,165,140...22,212,326

G

BCL2 interacting protein 3 like

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BNIP3L mRNA; dibenzo(a,l)pyrene results in decreased expression of BNIP3L protein

NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636

G

bromodomain containing 4

increases expression

dibenzo(a,l)pyrene results in increased expression of BRD4 mRNA

NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545

G

BUD31 homolog

decreases expression

dibenzo(a,l)pyrene results in decreased expression of BUD31 mRNA

NCBI chr 7:99,408,969...99,419,616
Ensembl chr 7:99,408,641...99,419,616

G

carbonic anhydrase 3

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CA3 mRNA

NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040

G

calcyclin binding protein

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CACYBP mRNA

NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027

G

calpain 2

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of CAPN2 mRNA

NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018

G

caspase 3

multiple interactions
increases cleavage

2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [dibenzo(a,l)pyrene results in increased cleavage of CASP3 protein]; Estradiol affects the reaction [dibenzo(a,l)pyrene results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin affects the reaction [dibenzo(a,l)pyrene results in increased cleavage of CASP3 protein]

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062

G

coiled-coil domain containing 82

increases expression

dibenzo(a,l)pyrene results in increased expression of CCDC82 mRNA

NCBI chr11:96,352,773...96,389,912
Ensembl chr11:96,349,241...96,389,956

G

cellular communication network factor 2

increases expression

dibenzo(a,l)pyrene results in increased expression of CCN2 mRNA

NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372

G

cyclin D1 binding protein 1

affects expression

dibenzo(a,l)pyrene affects the expression of CCNDBP1 mRNA

NCBI chr15:43,185,403...43,197,177
Ensembl chr15:43,185,118...43,197,177

G

C-C motif chemokine receptor 2

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CCR2 mRNA

NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940

G

cell division cycle 37 like 1, HSP90 cochaperone

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CDC37L1 mRNA

NCBI chr 9:4,679,569...4,708,399
Ensembl chr 9:4,679,559...4,708,399

G

cadherin 1

increases expression
decreases expression

dibenzo(a,l)pyrene results in increased expression of CDH1 mRNA
dibenzo(a,l)pyrene results in decreased expression of CDH1 mRNA

PMID:15735009 PMID:31255691

NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537

G

cadherin 17

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CDH17 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CDH17 mRNA

NCBI chr 8:94,127,162...94,217,278
Ensembl chr 8:94,127,162...94,217,303

G

cadherin 2

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of CDH2 mRNA

NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946

G

cyclin dependent kinase inhibitor 1A

increases expression
multiple interactions

dibenzo(a,l)pyrene results in increased expression of CDKN1A mRNA
[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of CDKN1A mRNA

PMID:15735009 PMID:17690111 PMID:22409540 PMID:26496743

NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337

G

CEA cell adhesion molecule 5

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CEACAM5 mRNA

NCBI chr19:41,708,626...41,730,433
Ensembl chr19:41,708,585...41,730,433

G

CEA cell adhesion molecule 6

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CEACAM6 mRNA

NCBI chr19:41,755,530...41,772,211
Ensembl chr19:41,750,977...41,772,211

G

centrosomal protein 43

decreases methylation

dibenzo(a,l)pyrene results in decreased methylation of CEP43 promoter

NCBI chr 6:166,999,397...167,052,718
Ensembl chr 6:166,999,174...167,052,718

G

carboxylesterase 4A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CES4A mRNA

NCBI chr16:66,988,589...67,010,417
Ensembl chr16:66,988,589...67,010,417

G

cilia and flagella associated protein 73

affects expression

dibenzo(a,l)pyrene affects the expression of CFAP73 mRNA

NCBI chr12:113,149,724...113,159,276
Ensembl chr12:113,149,724...113,159,276

G

cofilin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CFL1 protein

NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026

G

cyclic GMP-AMP synthase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CGAS mRNA

NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297

G

chromodomain helicase DNA binding protein 2

increases expression

dibenzo(a,l)pyrene results in increased expression of CHD2 mRNA

NCBI chr15:92,900,324...93,027,996
Ensembl chr15:92,886,203...93,027,996

G

chimerin 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CHN2 mRNA

NCBI chr 7:29,146,591...29,514,328
Ensembl chr 7:29,146,547...29,514,328

G

claudin 3

increases expression

dibenzo(a,l)pyrene results in increased expression of CLDN3 mRNA

NCBI chr 7:73,768,997...73,770,270
Ensembl chr 7:73,768,997...73,770,270

G

claudin 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CLDN4 mRNA

NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690

G

claudin 7

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CLDN7 mRNA

NCBI chr17:7,259,903...7,263,213
Ensembl chr17:7,259,903...7,263,983

G

claudin 8

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CLDN8 mRNA

NCBI chr21:30,214,006...30,216,097
Ensembl chr21:30,214,006...30,216,097

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CLPP mRNA

NCBI chr19:6,361,531...6,370,242
Ensembl chr19:6,361,531...6,370,242

G

CCR4-NOT transcription complex subunit 6 like

increases expression

dibenzo(a,l)pyrene results in increased expression of CNOT6L mRNA

NCBI chr 4:77,713,387...77,820,269
Ensembl chr 4:77,713,387...77,819,615

G

centriolin

increases expression

dibenzo(a,l)pyrene results in increased expression of CNTRL mRNA

NCBI chr 9:121,074,955...121,177,610
Ensembl chr 9:121,074,660...121,177,729

G

COPI coat complex subunit alpha

decreases expression

dibenzo(a,l)pyrene results in decreased expression of COPA mRNA

NCBI chr 1:160,288,594...160,343,250
Ensembl chr 1:160,288,594...160,343,566

G

cellular repressor of E1A stimulated genes 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CREG1 mRNA

NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805

G

cystatin B

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CSTB mRNA

NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330

G

cathepsin L

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CTSL mRNA

NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469

G

cortactin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of CTTN mRNA

NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584

G

cytochrome P450 family 1 subfamily A member 1

multiple interactions
increases activity
increases expression
decreases expression
affects expression

[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A1 mRNA; TP53 protein affects the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1A1 protein]
CYP1A1 protein results in increased activity of dibenzo(a,l)pyrene
dibenzo(a,l)pyrene results in increased expression of CYP1A1 mRNA; dibenzo(a,l)pyrene results in increased expression of CYP1A1 protein
dibenzo(a,l)pyrene promotes the reaction [Dust results in increased expression of CYP1A1 protein]; Dust promotes the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1A1 protein]
1,2,5,6-dibenzanthracene promotes the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1A1 mRNA]; dibenzo(a,l)pyrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1A1 mRNA]; dibenzo(a,l)pyrene promotes the reaction [1,2,5,6-dibenzanthracene results in increased expression of CYP1A1 mRNA]; dibenzo(a,l)pyrene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
dibenzo(a,l)pyrene results in decreased expression of CYP1A1 mRNA
dibenzo(a,l)pyrene affects the expression of CYP1A1 mRNA

PMID:12117779 PMID:15566942 PMID:15606143 PMID:16269432 PMID:17060372 More...

NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536

G

cytochrome P450 family 1 subfamily A member 2

increases activity
multiple interactions
increases expression

CYP1A2 protein results in increased activity of dibenzo(a,l)pyrene
[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA
dibenzo(a,l)pyrene results in increased expression of CYP1A2 mRNA
[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA

PMID:15606143 PMID:16269432 PMID:17690111 PMID:18711122

NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607

G

cytochrome P450 family 1 subfamily B member 1

increases expression
multiple interactions
increases activity
increases metabolic processing
decreases activity
decreases expression
decreases response to substance
affects expression

dibenzo(a,l)pyrene results in increased expression of CYP1B1 mRNA
[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA; [phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA; [Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA
CYP1B1 protein results in increased activity of dibenzo(a,l)pyrene
CYP1B1 protein results in increased metabolism of dibenzo(a,l)pyrene
dibenzo(a,l)pyrene promotes the reaction [Dust results in increased expression of CYP1B1 protein]; Dust promotes the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1B1 protein]
dibenzo(a,l)pyrene results in increased expression of CYP1B1 mRNA; dibenzo(a,l)pyrene results in increased expression of CYP1B1 protein
[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene; [fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene; dibenzo(a,l)pyrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]
[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene; [fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene
dibenzo(a,l)pyrene results in decreased expression of CYP1B1 mRNA
CYP1B1 gene mutant form results in decreased susceptibility to dibenzo(a,l)pyrene
dibenzo(a,l)pyrene affects the expression of CYP1B1 mRNA

PMID:12117779 PMID:15566942 PMID:15606143 PMID:17060372 PMID:17612574 More...

NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902

G

cytochrome P450 family 2 subfamily C member 19

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP2C19 mRNA

NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547

G

damage specific DNA binding protein 2

increases expression

dibenzo(a,l)pyrene results in increased expression of DDB2 mRNA

PMID:15735009 PMID:22409540

NCBI chr11:47,214,454...47,239,217
Ensembl chr11:47,214,465...47,239,217

G

DEP domain containing 1B

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DEPDC1B mRNA

NCBI chr 5:60,596,912...60,700,166
Ensembl chr 5:60,596,912...60,700,190

G

diacylglycerol O-acyltransferase 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DGAT1 mRNA

NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910

G

diacylglycerol O-acyltransferase 2 like 6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DGAT2L6 mRNA

NCBI chr X:70,177,483...70,205,704
Ensembl chr X:70,177,483...70,205,704

G

dihydrofolate reductase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DHFR protein

NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983

G

dihydrolipoamide dehydrogenase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DLD mRNA

NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730

G

desmocollin 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DSC2 mRNA

NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,545...31,102,600

G

desmocollin 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DSC3 mRNA

NCBI chr18:30,989,365...31,042,742
Ensembl chr18:30,989,365...31,042,815

G

desmoglein 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DSG2 mRNA

NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,497,624...31,551,351

G

desmoglein 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DSG3 mRNA

NCBI chr18:31,447,741...31,478,702
Ensembl chr18:31,447,741...31,478,702

G

desmoplakin

increases expression
decreases expression

dibenzo(a,l)pyrene results in increased expression of DSP mRNA
dibenzo(a,l)pyrene results in decreased expression of DSP mRNA

PMID:25908611 PMID:31255691

NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,326...7,586,717

G

dystonin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of DST mRNA

NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830

G

dual specificity phosphatase 1

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of DUSP1 mRNA

NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195

G

dynein 2 intermediate chain 2

increases expression

dibenzo(a,l)pyrene results in increased expression of DYNC2I2 mRNA

NCBI chr 9:128,633,653...128,684,460
Ensembl chr 9:128,633,653...128,656,847

G

E2F transcription factor 1

increases expression

dibenzo(a,l)pyrene results in increased expression of E2F1 mRNA

NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385

G

E2F transcription factor 6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of E2F6 mRNA

NCBI chr 2:11,444,375...11,466,161
Ensembl chr 2:11,444,375...11,466,177

G

EBNA1 binding protein 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of EBNA1BP2 mRNA

NCBI chr 1:43,164,174...43,172,570
Ensembl chr 1:43,164,175...43,270,936

G

endothelin converting enzyme 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ECE1 mRNA

NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572

G

endothelin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of EDN1 mRNA

NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of EHHADH mRNA

NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990

G

eukaryotic translation initiation factor 4 gamma 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of EIF4G2 mRNA

NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940

G

enolase 1

increases expression

dibenzo(a,l)pyrene results in increased expression of ENO1 protein

NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190

G

EPH receptor B6

affects expression

dibenzo(a,l)pyrene affects the expression of EPHB6 mRNA

NCBI chr 7:142,855,076...142,871,093
Ensembl chr 7:142,855,061...142,871,094

G

F11 receptor

decreases expression

dibenzo(a,l)pyrene results in decreased expression of F11R mRNA

NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175

G

fatty acid binding protein 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of FABP1 mRNA

NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062

G

family with sequence similarity 110 member A

increases expression

dibenzo(a,l)pyrene results in increased expression of FAM110A mRNA

NCBI chr20:833,715...846,277
Ensembl chr20:833,715...857,463

G

family with sequence similarity 136 member A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FAM136A mRNA

NCBI chr 2:70,295,976...70,302,067
Ensembl chr 2:70,295,976...70,302,067

G

family with sequence similarity 220 member A

affects expression

dibenzo(a,l)pyrene affects the expression of FAM220A mRNA

NCBI chr 7:6,329,411...6,348,967
Ensembl chr 7:6,329,411...6,348,981

G

phenylalanyl-tRNA synthetase subunit beta

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FARSB mRNA

NCBI chr 2:222,566,899...222,656,092
Ensembl chr 2:222,566,899...222,656,092

G

Fas cell surface death receptor

increases expression

dibenzo(a,l)pyrene results in increased expression of FAS mRNA

NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605

G

fatty acid synthase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FASN mRNA

NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294

G

F-box and leucine rich repeat protein 20

increases expression

dibenzo(a,l)pyrene results in increased expression of FBXL20 mRNA

NCBI chr17:39,252,663...39,402,556
Ensembl chr17:39,252,663...39,402,523

G

F-box and WD repeat domain containing 7

increases expression

dibenzo(a,l)pyrene results in increased expression of FBXW7 mRNA

NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092

G

FCH and double SH3 domains 1

affects expression

dibenzo(a,l)pyrene affects the expression of FCHSD1 mRNA

NCBI chr 5:141,639,302...141,651,418
Ensembl chr 5:141,639,302...141,651,418

G

ferrochelatase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FECH mRNA

NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732

G

fibroblast growth factor 13

affects expression

dibenzo(a,l)pyrene affects the expression of FGF13 mRNA

NCBI chr X:138,614,727...139,205,023
Ensembl chr X:138,614,727...139,222,777

G

four and a half LIM domains 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FHL1 mRNA

NCBI chr X:136,146,702...136,211,359
Ensembl chr X:136,146,702...136,211,359

G

filamin B

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FLNB mRNA

NCBI chr 3:58,008,422...58,172,251
Ensembl chr 3:58,008,398...58,172,251

G

follistatin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FST mRNA

NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134

G

fucosyltransferase 8

decreases expression

dibenzo(a,l)pyrene results in decreased expression of FUT8 mRNA

NCBI chr14:65,356,842...65,744,121
Ensembl chr14:65,410,592...65,744,121

G

FXYD domain containing ion transport regulator 1

increases expression

dibenzo(a,l)pyrene results in increased expression of FXYD1 mRNA

NCBI chr19:35,137,188...35,143,109
Ensembl chr19:35,138,824...35,143,109

G

glucose-6-phosphate dehydrogenase

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of G6PD mRNA

NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572

G

growth arrest and DNA damage inducible alpha

multiple interactions
increases expression

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of GADD45A mRNA
dibenzo(a,l)pyrene results in increased expression of GADD45A mRNA

PMID:15735009 PMID:16269432 PMID:17690111

NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334

G

glucokinase

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of GCK mRNA

NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170

G

growth hormone inducible transmembrane protein

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GHITM mRNA

NCBI chr10:84,139,509...84,153,568
Ensembl chr10:84,139,482...84,154,841

G

gap junction protein alpha 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GJA1 mRNA

NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727

G

gap junction protein beta 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GJB3 mRNA

NCBI chr 1:34,781,214...34,786,364
Ensembl chr 1:34,781,214...34,786,369

G

gap junction protein gamma 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GJC1 mRNA

NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816

G

gliomedin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GLDN mRNA

NCBI chr15:51,341,655...51,413,365
Ensembl chr15:51,341,655...51,408,005

G

GLI family zinc finger 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GLI1 mRNA

NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268

G

glutaredoxin 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of GLRX2 mRNA

NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114

G

G protein subunit beta 2

increases expression

dibenzo(a,l)pyrene results in increased expression of GNB2 mRNA

NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174

G

glutathione S-transferase alpha 1

multiple interactions
decreases expression
increases expression

GSTA1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]; GSTA1 protein binds to and affects the metabolism of and results in decreased susceptibility to dibenzo(a,l)pyrene analog
dibenzo(a,l)pyrene results in decreased expression of GSTA1 mRNA
dibenzo(a,l)pyrene results in increased expression of GSTA1 mRNA

PMID:11849043 PMID:12067250 PMID:31255691 PMID:32890658

NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860

G

glutathione S-transferase alpha 3

multiple interactions

GSTA3 protein binds to and affects the metabolism of and results in decreased susceptibility to dibenzo(a,l)pyrene analog

NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698

G

glutathione S-transferase mu 1

multiple interactions

GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]

NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039

G

glutathione S-transferase pi 1

decreases response to substance
multiple interactions

GSTP1 results in decreased susceptibility to dibenzo(a,l)pyrene
GSTP1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]

PMID:11849043 PMID:19330882

NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656

G

H19 imprinted maternally expressed transcript

decreases expression

dibenzo(a,l)pyrene results in decreased expression of H19 mRNA

NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552

G

H2A clustered histone 11

increases expression

dibenzo(a,l)pyrene results in increased expression of H2AC11 protein

NCBI chr 6:27,133,043...27,133,535
Ensembl chr 6:27,133,043...27,133,535

G

H2A.X variant histone

increases phosphorylation
multiple interactions

dibenzo(a,l)pyrene results in increased phosphorylation of H2AX protein
2-(morpholin-4-yl)benzo(h)chromen-4-one inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of H2AX protein]

NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465

G

hepcidin antimicrobial peptide

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of HAMP mRNA

NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143

G

HCLS1 associated protein X-1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HAX1 mRNA

NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of HIF1A mRNA

NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259

G

hypoxia inducible lipid droplet associated

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HILPDA mRNA

NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418

G

high mobility group box 1

increases expression

dibenzo(a,l)pyrene results in increased expression of HMGB1 mRNA

NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HMGCR mRNA

NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HMGCS1 mRNA

NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512

G

high mobility group nucleosome binding domain 5

increases expression

dibenzo(a,l)pyrene results in increased expression of HMGN5 mRNA

NCBI chr X:81,113,699...81,201,913
Ensembl chr X:81,113,699...81,201,913

G

heterogeneous nuclear ribonucleoprotein A2/B1

increases expression

dibenzo(a,l)pyrene results in increased expression of HNRNPA2B1 protein

NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529

G

homeobox B1

decreases methylation

dibenzo(a,l)pyrene results in decreased methylation of HOXB1 promoter

NCBI chr17:48,528,526...48,531,011
Ensembl chr17:48,528,526...48,531,011

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of HSD11B1 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of HSD11B1 mRNA

NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949

G

heat shock protein 90 alpha family class A member 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HSP90AA1 mRNA

NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699

G

heat shock protein family A (Hsp70) member 1A

increases expression

dibenzo(a,l)pyrene results in increased expression of HSPA1A protein

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

heat shock protein family A (Hsp70) member 4 like

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HSPA4L mRNA

NCBI chr 4:127,781,796...127,840,733
Ensembl chr 4:127,781,821...127,840,733

G

heat shock protein family H (Hsp110) member 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of HSPH1 mRNA

NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388

G

HIV-1 Tat specific factor 1

increases expression

dibenzo(a,l)pyrene results in increased expression of HTATSF1 mRNA

NCBI chr X:136,497,229...136,512,346
Ensembl chr X:136,497,079...136,512,346

G

inhibitor of DNA binding 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ID1 mRNA

NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515

G

inhibitor of DNA binding 2

increases expression

dibenzo(a,l)pyrene results in increased expression of ID2 mRNA

NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461

G

immediate early response 3 interacting protein 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of IER3IP1 mRNA

NCBI chr18:47,152,834...47,176,364
Ensembl chr18:47,152,834...47,176,364

G

immediate early response 5

decreases expression

dibenzo(a,l)pyrene results in decreased expression of IER5 mRNA

NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900

G

insulin like growth factor 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of IGF1 mRNA

NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744

G

insulin like growth factor binding protein 1

increases expression
multiple interactions

dibenzo(a,l)pyrene results in increased expression of IGFBP1 mRNA
[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of IGFBP1 mRNA

PMID:16269432 PMID:17690111

NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660

G

insulin like growth factor binding protein 4

increases expression

dibenzo(a,l)pyrene results in increased expression of IGFBP4 mRNA

NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725

G

interleukin 13 receptor subunit alpha 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of IL13RA2 mRNA

NCBI chr X:115,003,982...115,017,616
Ensembl chr X:115,003,975...115,019,977

G

interleukin 18 receptor 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of IL18R1 mRNA

NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777

G

interleukin 6 receptor

increases expression

dibenzo(a,l)pyrene results in increased expression of IL6RA mRNA

NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450

G

INO80 complex subunit B

increases expression

dibenzo(a,l)pyrene results in increased expression of INO80B mRNA

NCBI chr 2:74,455,087...74,457,944
Ensembl chr 2:74,455,087...74,457,944

G

integrator complex subunit 11

decreases expression

dibenzo(a,l)pyrene results in decreased expression of INTS11 mRNA

NCBI chr 1:1,311,600...1,324,660
Ensembl chr 1:1,311,585...1,324,687

G

IQ motif containing GTPase activating protein 1

increases expression

dibenzo(a,l)pyrene results in increased expression of IQGAP1 mRNA

NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239

G

integrin subunit beta 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ITGB1 mRNA

NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792

G

jagunal homolog 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of JAGN1 mRNA

NCBI chr 3:9,890,610...9,894,349
Ensembl chr 3:9,890,574...9,894,349

G

junction plakoglobin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of JUP mRNA

NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931

G

lysine demethylase 1A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of KDM1A mRNA

NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689

G

karyopherin subunit alpha 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of KPNA2 mRNA

NCBI chr17:68,035,735...68,046,854
Ensembl chr17:68,035,636...68,047,364

G

KRAS proto-oncogene, GTPase

increases mutagenesis

dibenzo(a,l)pyrene results in increased mutagenesis of KRAS gene

NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936

G

keratin 18

decreases expression

dibenzo(a,l)pyrene results in decreased expression of KRT18 mRNA

NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906

G

keratin 6A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of KRT6A mRNA

NCBI chr12:52,487,176...52,493,257
Ensembl chr12:52,487,176...52,493,257

G

leucine aminopeptidase 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of LAP3 mRNA

NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972

G

lipopolysaccharide binding protein

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of LBP mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of LBP mRNA

NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013

G

low density lipoprotein receptor

decreases expression

dibenzo(a,l)pyrene results in decreased expression of LDLR mRNA

NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820

G

galectin 3

increases expression

dibenzo(a,l)pyrene results in increased expression of LGALS3 protein

NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423

G

leucine rich repeat containing 58

decreases expression

dibenzo(a,l)pyrene results in decreased expression of LRRC58 mRNA

NCBI chr 3:120,324,509...120,349,354
Ensembl chr 3:120,324,509...120,349,354

G

lanosterol synthase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of LSS mRNA

NCBI chr21:46,188,446...46,228,774
Ensembl chr21:46,188,141...46,228,824

G

lymphotoxin beta

decreases expression

dibenzo(a,l)pyrene results in decreased expression of LTB mRNA

NCBI chr 6:31,580,558...31,582,425
Ensembl chr 6:31,580,525...31,582,522

G

mitogen-activated protein kinase kinase kinase kinase 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MAP4K4 mRNA

NCBI chr 2:101,697,707...101,894,690
Ensembl chr 2:101,696,850...101,894,690

G

mitogen-activated protein kinase 1

multiple interactions

dibenzo(a,l)pyrene results in increased phosphorylation of and results in increased activity of MAPK1 protein; pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK1 protein]

NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680

G

mitogen-activated protein kinase 14

multiple interactions

dibenzo(a,l)pyrene results in increased phosphorylation of and results in increased activity of MAPK14 protein; pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]; SB 203580 promotes the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]; U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]

NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236

G

mitogen-activated protein kinase 3

multiple interactions
decreases expression

dibenzo(a,l)pyrene results in increased phosphorylation of and results in increased activity of MAPK3 protein; pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK3 protein]
dibenzo(a,l)pyrene results in decreased expression of MAPK3 mRNA

PMID:16005925 PMID:31255691

NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506

G

methyl-CpG binding domain protein 5

affects expression

dibenzo(a,l)pyrene affects the expression of MBD5 mRNA

NCBI chr 2:148,020,927...148,516,971
Ensembl chr 2:148,021,011...148,516,971

G

malic enzyme 1

multiple interactions
decreases expression

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of ME1 mRNA
dibenzo(a,l)pyrene results in decreased expression of ME1 mRNA

PMID:18711122 PMID:31255691

NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051

G

MFSD2 lysolipid transporter A, lysophospholipid

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MFSD2A mRNA

NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968

G

MID1 interacting protein 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MID1IP1 mRNA

NCBI chr X:38,801,459...38,806,532
Ensembl chr X:38,801,440...38,806,537

G

marker of proliferation Ki-67

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MKI67 mRNA

NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423

G

metabolism of cobalamin associated D

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MMADHC mRNA

NCBI chr 2:149,569,637...149,587,775
Ensembl chr 2:149,569,637...149,587,778

G

membrane magnesium transporter 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MMGT1 mRNA

NCBI chr X:135,960,588...135,973,988
Ensembl chr X:135,960,588...135,974,029

G

matrix metallopeptidase 3

multiple interactions
decreases expression

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of MMP3 mRNA
dibenzo(a,l)pyrene results in decreased expression of MMP3 mRNA

PMID:17690111 PMID:25908611

NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609

G

mitochondrial ribosomal protein L11

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MRPL11 mRNA

NCBI chr11:66,435,075...66,438,848
Ensembl chr11:66,435,075...66,466,738

G

mitochondrial ribosomal protein L15

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MRPL15 mRNA

NCBI chr 8:54,135,241...54,148,514
Ensembl chr 8:54,135,241...54,148,514

G

mitochondrial ribosomal protein L47

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MRPL47 mRNA

NCBI chr 3:179,588,285...179,604,646
Ensembl chr 3:179,588,285...179,604,649

G

mitochondrial ribosomal protein S26

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MRPS26 mRNA

NCBI chr20:3,046,052...3,048,250
Ensembl chr20:3,046,052...3,048,250

G

mitochondrial ribosomal protein S7

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MRPS7 mRNA

NCBI chr17:75,261,879...75,266,376
Ensembl chr17:75,261,674...75,266,376

G

membrane spanning 4-domains A10

increases expression

dibenzo(a,l)pyrene results in increased expression of MS4A10 mRNA

NCBI chr11:60,785,333...60,801,305
Ensembl chr11:60,785,333...60,801,305

G

metallothionein 1E

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of MT1E mRNA

NCBI chr16:56,625,781...56,627,112
Ensembl chr16:56,625,475...56,627,112

G

metallothionein 2A

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of MT2A mRNA

NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497

G

metadherin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MTDH mRNA

NCBI chr 8:97,644,184...97,730,260
Ensembl chr 8:97,644,184...97,730,260

G

microtubule associated scaffold protein 1

increases expression

dibenzo(a,l)pyrene results in increased expression of MTUS1 mRNA

NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094

G

metaxin 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MTX2 mRNA

NCBI chr 2:176,269,442...176,338,025
Ensembl chr 2:176,269,395...176,338,025

G

mucin 1, cell surface associated

decreases expression

dibenzo(a,l)pyrene results in decreased expression of MUC1 mRNA

NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916

G

myosin light chain 6

increases expression

dibenzo(a,l)pyrene results in increased expression of MYL6 protein

NCBI chr12:56,158,359...56,161,579
Ensembl chr12:56,158,346...56,163,496

G

N-alpha-acetyltransferase 20, NatB catalytic subunit

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NAA20 mRNA

NCBI chr20:20,017,290...20,033,655
Ensembl chr20:20,017,310...20,033,655

G

NAD kinase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NADK mRNA

NCBI chr 1:1,751,232...1,780,514
Ensembl chr 1:1,751,232...1,780,457

G

nuclear cap binding protein subunit 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NCBP1 mRNA

NCBI chr 9:97,633,821...97,673,748
Ensembl chr 9:97,633,668...97,673,748

G

nuclear receptor coactivator 4

affects expression

dibenzo(a,l)pyrene affects the expression of NCOA4 mRNA

NCBI chr10:46,005,088...46,030,623
Ensembl chr10:46,005,088...46,030,623

G

NADH:ubiquinone oxidoreductase complex assembly factor 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NDUFAF4 mRNA

NCBI chr 6:96,889,315...96,897,891
Ensembl chr 6:96,889,315...96,897,891

G

nectin cell adhesion molecule 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PVRL1 mRNA

NCBI chr11:119,638,098...119,729,200
Ensembl chr11:119,623,408...119,729,200

G

nectin cell adhesion molecule 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NECTIN4 mRNA

NCBI chr 1:161,070,998...161,089,558
Ensembl chr 1:161,070,998...161,089,558

G

nuclear factor I B

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NFIB mRNA

NCBI chr 9:14,081,843...14,532,077
Ensembl chr 9:14,081,843...14,398,983

G

NFKB inhibitor alpha

increases expression

dibenzo(a,l)pyrene results in increased expression of NFKBIA mRNA

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

NME/NM23 nucleoside diphosphate kinase 1

increases expression
decreases expression

dibenzo(a,l)pyrene results in increased expression of NME1 protein
dibenzo(a,l)pyrene results in decreased expression of NME1 mRNA

PMID:18495319 PMID:25908611

NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428

G

NAD(P)H quinone dehydrogenase 1

multiple interactions
decreases expression

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of NQO1 mRNA
dibenzo(a,l)pyrene results in decreased expression of NQO1 mRNA

PMID:18711122 PMID:26496743 PMID:31255691

NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668

G

nuclear receptor subfamily 1 group I member 2

multiple interactions

dibenzo(a,l)pyrene binds to and results in increased activity of NR1I2 protein

NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487

G

nuclear receptor binding SET domain protein 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NSD2 mRNA

NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207

G

nucleoporin 205

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NUP205 mRNA

NCBI chr 7:135,557,917...135,648,753
Ensembl chr 7:135,557,917...135,648,757

G

nucleoporin 58

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of NUP58 mRNA

NCBI chr13:25,301,625...25,349,800
Ensembl chr13:25,301,524...25,365,390

G

nuclear protein 1, transcriptional regulator

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of NUPR1 mRNA

NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008

G

NUS1 dehydrodolichyl diphosphate synthase subunit

decreases expression

dibenzo(a,l)pyrene results in decreased expression of NUS1 mRNA

NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727

G

olfactory receptor family 7 subfamily E member 24

increases expression

dibenzo(a,l)pyrene results in increased expression of OR7E178 mRNA

NCBI chr19:9,206,488...9,252,625
Ensembl chr19:9,247,344...9,252,625

G

oxysterol binding protein like 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of OSBPL3 mRNA

NCBI chr 7:24,796,537...24,981,845
Ensembl chr 7:24,796,540...24,981,634

G

oligosaccharyltransferase complex non-catalytic subunit

decreases expression

dibenzo(a,l)pyrene results in decreased expression of OSTC mRNA

NCBI chr 4:108,650,599...108,667,820
Ensembl chr 4:108,650,585...108,667,820

G

PAK1 interacting protein 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PAK1IP1 mRNA

NCBI chr 6:10,690,865...10,709,782
Ensembl chr 6:10,694,972...10,709,782

G

par-3 family cell polarity regulator

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PARD3 mRNA

NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325

G

PATJ crumbs cell polarity complex component

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PATJ mRNA

NCBI chr 1:61,742,480...62,163,915
Ensembl chr 1:61,742,477...62,178,675

G

proliferating cell nuclear antigen

increases expression
multiple interactions

dibenzo(a,l)pyrene results in increased expression of PCNA mRNA
[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of PCNA mRNA

PMID:17690111 PMID:22409540

NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626

G

programmed cell death 4

increases methylation

dibenzo(a,l)pyrene results in increased methylation of PDCD4 promoter

NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006

G

programmed cell death 6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PDCD6 mRNA

PMID:25908611 PMID:31255691

NCBI chr 5:271,646...314,974
Ensembl chr 5:271,621...314,974

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PIK3CA mRNA

NCBI chr 3:179,148,126...179,240,093
Ensembl chr 3:179,148,114...179,240,093

G

phospholipase A2 inhibitor and LY6/PLAUR domain containing

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PINLYP mRNA

NCBI chr19:43,575,509...43,582,098
Ensembl chr19:43,575,801...43,583,964

G

plakophilin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PKP1 mRNA

NCBI chr 1:201,283,506...201,332,989
Ensembl chr 1:201,283,452...201,332,993

G

plasminogen activator, tissue type

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLAT mRNA

NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709

G

phospholipase C beta 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLCB1 mRNA

NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360

G

phospholipase C gamma 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLCG2 mRNA

NCBI chr16:81,779,291...81,962,685
Ensembl chr16:81,779,279...81,962,685

G

placenta expressed transcript 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLET1 mRNA

NCBI chr11:112,248,153...112,260,860
Ensembl chr11:112,248,153...112,260,860

G

perilipin 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLIN2 mRNA

NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290

G

pyridoxal phosphate binding protein

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PLPBP mRNA

NCBI chr 8:37,762,546...37,779,768
Ensembl chr 8:37,762,595...37,779,768

G

inorganic pyrophosphatase 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PPA1 mRNA

NCBI chr10:70,202,835...70,233,429
Ensembl chr10:70,202,835...70,233,911

G

peptidylprolyl isomerase D

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PPID mRNA

NCBI chr 4:158,709,127...158,723,396
Ensembl chr 4:158,709,127...158,723,396

G

protein phosphatase, Mg2+/Mn2+ dependent 1D

increases expression

dibenzo(a,l)pyrene results in increased expression of PPM1D mRNA; dibenzo(a,l)pyrene results in increased expression of PPM1D protein

NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280

G

protein phosphatase 1 catalytic subunit beta

affects expression

dibenzo(a,l)pyrene affects the expression of PPP1CB mRNA

NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940

G

protein regulator of cytokinesis 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRC1 mRNA

NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629

G

peroxiredoxin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRDX1 mRNA

PMID:25908611 PMID:31255691

NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732

G

peroxiredoxin 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRDX4 mRNA

NCBI chr X:23,667,493...23,686,397
Ensembl chr X:23,664,262...23,686,397

G

protein kinase C zeta

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRKCZ mRNA

NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395

G

PRKR interacting protein 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRKRIP1 mRNA

NCBI chr 7:102,396,363...102,426,666
Ensembl chr 7:102,363,872...102,426,676

G

protein arginine methyltransferase 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRMT1 mRNA

NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029

G

serine protease 12

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRSS12 mRNA

NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003

G

serine protease 22

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PRSS22 mRNA

NCBI chr16:2,852,730...2,858,170
Ensembl chr16:2,852,730...2,858,170

G

proteasome 20S subunit alpha 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMA2 mRNA

NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,916,828...42,932,185

G

proteasome 20S subunit alpha 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMA3 mRNA

NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012

G

proteasome 20S subunit alpha 5

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMA5 mRNA

NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448

G

proteasome 20S subunit beta 6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMB6 mRNA

NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502

G

proteasome 26S subunit, non-ATPase 12

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMD12 mRNA

NCBI chr17:67,337,916...67,366,577
Ensembl chr17:67,337,916...67,366,605

G

proteasome 26S subunit, non-ATPase 14

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PSMD14 mRNA

NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717

G

phosphatase and tensin homolog

increases methylation

dibenzo(a,l)pyrene results in increased methylation of PTEN promoter

NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930

G

prostaglandin reductase 1

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of PTGR1 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of PTGR1 mRNA

NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893

G

prostaglandin reductase 3

increases expression

dibenzo(a,l)pyrene results in increased expression of PTGR3 mRNA

NCBI chr18:75,195,108...75,209,139
Ensembl chr18:75,195,113...75,209,139

G

protein tyrosine kinase 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of PTK2 mRNA

NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216

G

pumilio RNA binding family member 2

increases expression

dibenzo(a,l)pyrene results in increased expression of PUM2 mRNA

NCBI chr 2:20,248,691...20,352,253
Ensembl chr 2:20,248,691...20,352,234

G

RAB13, member RAS oncogene family

increases expression

dibenzo(a,l)pyrene results in increased expression of RAB13 mRNA

NCBI chr 1:153,981,650...153,990,708
Ensembl chr 1:153,981,617...153,986,358

G

RAB6A, member RAS oncogene family

increases expression

dibenzo(a,l)pyrene results in increased expression of RAB6A mRNA

NCBI chr11:73,675,638...73,761,074
Ensembl chr11:73,675,638...73,761,137

G

RNA binding motif protein 8A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of RBM8A mRNA

NCBI chr 1:145,921,556...145,927,484
Ensembl chr 1:145,921,556...145,927,678

G

ring-box 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of RBX1 mRNA

NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309

G

ribosome production factor 1 homolog

decreases expression

dibenzo(a,l)pyrene results in decreased expression of RPF1 mRNA

NCBI chr 1:84,479,266...84,498,352
Ensembl chr 1:84,479,259...84,498,352

G

ribosomal protein L17

increases expression

dibenzo(a,l)pyrene results in increased expression of RPL17 mRNA

NCBI chr18:49,488,481...49,492,465
Ensembl chr18:49,488,453...49,492,508

G

ribosomal protein L36a

increases expression

dibenzo(a,l)pyrene results in increased expression of RPL36A mRNA

NCBI chr X:101,391,011...101,396,155
Ensembl chr X:101,390,824...101,396,155

G

ribosomal protein S19 binding protein 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of RPS19BP1 mRNA

NCBI chr22:39,529,093...39,532,748
Ensembl chr22:39,529,093...39,532,761

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of RRAD mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of RRAD mRNA

NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535

G

S100 calcium binding protein A6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of S100A6 mRNA

NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244

G

serum amyloid A3, pseudogene

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SAA3 mRNA

NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132

G

spermidine/spermine N1-acetyltransferase 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SAT1 mRNA

NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210

G

stearoyl-CoA desaturase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SCD mRNA

NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826

G

SEC11 homolog A, signal peptidase complex subunit

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SEC11A mRNA

NCBI chr15:84,669,544...84,716,139
Ensembl chr15:84,669,538...84,716,460

G

selenoprotein S

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SELENOS mRNA

NCBI chr15:101,270,809...101,277,485
Ensembl chr15:101,270,817...101,277,500

G

serpin family A member 3

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SERPINA3 mRNA

NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055

G

serpin family D member 1

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of SERPIND1 mRNA

NCBI chr22:20,774,113...20,787,720
Ensembl chr22:20,774,113...20,787,720

G

solute carrier family 16 member 1

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of SLC16A1 mRNA

NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593

G

solute carrier family 19 member 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SLC19A1 mRNA

NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365

G

solute carrier family 26 member 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SLC26A4 mRNA

NCBI chr 7:107,660,828...107,717,809
Ensembl chr 7:107,660,828...107,717,809

G

solute carrier family 36 member 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SLC36A1 mRNA

NCBI chr 5:151,344,596...151,556,085
Ensembl chr 5:151,437,046...151,492,379

G

solute carrier family 5 member 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SLC5A1 mRNA

NCBI chr22:32,043,261...32,113,029
Ensembl chr22:32,043,261...32,113,029

G

solute carrier family 6 member 9

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] results in increased expression of SLC6A9 mRNA

NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467

G

SMAD family member 3

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SMAD3 mRNA

NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173

G

small nuclear ribonucleoprotein D3 polypeptide

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SNRPD3 mRNA

NCBI chr22:24,555,650...24,574,971
Ensembl chr22:24,555,958...24,582,052

G

superoxide dismutase 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SOD1 mRNA

NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931

G

SON DNA and RNA binding protein

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SON mRNA

NCBI chr21:33,543,038...33,577,481
Ensembl chr21:33,543,038...33,577,481

G

SRY-box transcription factor 13

affects expression

dibenzo(a,l)pyrene affects the expression of SOX13 mRNA

NCBI chr 1:204,073,115...204,127,743
Ensembl chr 1:204,073,115...204,127,743

G

signal peptidase complex subunit 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SPCS3 mRNA

NCBI chr 4:176,319,966...176,332,245
Ensembl chr 4:176,319,966...176,332,245

G

secreted phosphoprotein 1

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SPP1 mRNA

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

spectrin beta, non-erythrocytic 2

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of SPTBN2 mRNA

NCBI chr11:66,682,497...66,744,682
Ensembl chr11:66,682,496...66,744,670

G

SRC proto-oncogene, non-receptor tyrosine kinase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRC mRNA

NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050

G

signal recognition particle 14

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRP14 mRNA

NCBI chr15:40,035,690...40,039,202
Ensembl chr15:40,035,690...40,039,181

G

signal recognition particle 72

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRP72 mRNA

NCBI chr 4:56,467,617...56,503,681
Ensembl chr 4:56,467,617...56,503,681

G

signal recognition particle 9

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRP9 mRNA

NCBI chr 1:225,777,826...225,790,464
Ensembl chr 1:225,777,813...225,790,468

G

serine and arginine rich splicing factor 6

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRSF6 mRNA

NCBI chr20:43,457,896...43,464,243
Ensembl chr20:43,457,893...43,466,046

G

sulfiredoxin 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SRXN1 mRNA

NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200

G

signal sequence receptor subunit 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of SSR2 mRNA

NCBI chr 1:156,009,048...156,020,951
Ensembl chr 1:156,009,048...156,020,951

G

stromal interaction molecule 1

increases expression

dibenzo(a,l)pyrene results in increased expression of STIM1 mRNA

NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210

G

stomatin like 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of STOML2 mRNA

NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195

G

striatin 3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of STRN3 mRNA

NCBI chr14:30,893,804...31,026,379
Ensembl chr14:30,893,799...31,026,401

G

SYF2 pre-mRNA splicing factor

increases expression

dibenzo(a,l)pyrene results in increased expression of SYF2 mRNA

NCBI chr 1:25,222,276...25,232,502
Ensembl chr 1:25,222,276...25,232,502

G

tachykinin precursor 4

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TAC4 mRNA

NCBI chr17:49,838,300...49,848,069
Ensembl chr17:49,838,300...49,848,069

G

TATA-box binding protein associated factor 9

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TAF9 mRNA

NCBI chr 5:69,364,743...69,369,824
Ensembl chr 5:69,362,026...69,370,013

G

TBC1 domain family member 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TBC1D2 mRNA

NCBI chr 9:98,198,998...98,255,649
Ensembl chr 9:98,199,011...98,255,649

G

tubulin folding cofactor C

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TBCC mRNA

NCBI chr 6:42,744,498...42,746,103
Ensembl chr 6:42,744,498...42,746,103

G

transforming growth factor beta regulator 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TBRG1 mRNA

NCBI chr11:124,622,864...124,635,926
Ensembl chr11:124,622,836...124,635,926

G

transferrin

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of TF mRNA

NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641

G

tissue factor pathway inhibitor 2

increases expression

dibenzo(a,l)pyrene results in increased expression of TFPI2 mRNA

NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753

G

thyroid hormone receptor associated protein 3

increases expression

dibenzo(a,l)pyrene results in increased expression of THRAP3 mRNA

NCBI chr 1:36,207,637...36,305,357
Ensembl chr 1:36,224,432...36,305,357

G

translocase of inner mitochondrial membrane 17A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TIMM17A mRNA

NCBI chr 1:201,955,503...201,970,664
Ensembl chr 1:201,955,503...201,970,664

G

TCDD inducible poly(ADP-ribose) polymerase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TIPARP mRNA

NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770

G

tight junction protein 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TJP2 mRNA

NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615

G

TLC domain containing 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TLCD2 mRNA

NCBI chr17:1,702,816...1,710,377
Ensembl chr17:1,702,816...1,710,377

G

transmembrane p24 trafficking protein 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TMED2 mRNA

NCBI chr12:123,584,552...123,598,582
Ensembl chr12:123,584,533...123,598,582

G

transmembrane protein 128

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TMEM128 mRNA

NCBI chr 4:4,235,542...4,248,223
Ensembl chr 4:4,235,542...4,248,223

G

DNA topoisomerase I

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TOP1 mRNA

NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487

G

tumor protein p53

multiple interactions
increases expression
increases phosphorylation
increases response to substance

pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]; SB 203580 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]; U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of TP53 protein]
[dibenzo(a,l)pyrene co-treated with sodium arsenite] results in increased expression of TRP53 protein
dibenzo(a,l)pyrene results in increased expression of TRP53 protein
dibenzo(a,l)pyrene results in increased expression of TP53 protein
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]; dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein; Estradiol promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin promotes the reaction [dibenzo(a,l)pyrene affects the localization of and results in increased expression of TP53 protein]; TP53 protein affects the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1A1 protein]
TP53 protein results in increased susceptibility to dibenzo(a,l)pyrene

PMID:15548639 PMID:16005925 PMID:17961608 PMID:20353797 PMID:24954032 More...

NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546

G

tumor protein p63

increases expression

dibenzo(a,l)pyrene results in increased expression of TRP63 mRNA

NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276

G

tripeptidyl peptidase 2

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TPP2 mRNA

NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958

G

tripartite motif containing 41

increases expression

dibenzo(a,l)pyrene results in increased expression of TRIM41 mRNA

NCBI chr 5:181,223,281...181,235,808
Ensembl chr 5:181,222,499...181,235,808

G

thyroid hormone receptor interactor 13

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TRIP13 mRNA

NCBI chr 5:892,884...919,348
Ensembl chr 5:892,884...919,357

G

TSC22 domain family member 3

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of TSC22D3 mRNA

NCBI chr X:107,713,221...107,775,988
Ensembl chr X:107,713,221...107,777,342

G

tetraspanin 13

increases expression

dibenzo(a,l)pyrene results in increased expression of TSPAN13 mRNA

NCBI chr 7:16,753,755...16,784,536
Ensembl chr 7:16,753,755...16,784,536

G

tetratricopeptide repeat domain 21A

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TTC21A mRNA

NCBI chr 3:39,107,680...39,138,900
Ensembl chr 3:39,107,680...39,138,903

G

tubulin alpha 1a

increases expression

dibenzo(a,l)pyrene results in increased expression of TUBA1A mRNA

NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,324

G

tubulin alpha 1c

increases expression

dibenzo(a,l)pyrene results in increased expression of TUBA1C protein

NCBI chr12:49,227,926...49,274,600
Ensembl chr12:49,188,736...49,274,600

G

tubulin beta class I

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of TUBB5 mRNA; [Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of TUBB5 mRNA

NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538

G

tubulin beta 4B class IVb

increases expression

dibenzo(a,l)pyrene results in increased expression of TUBB4B mRNA

NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707

G

thioredoxin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of TXN mRNA

NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507

G

transmembrane immune signaling adaptor TYROBP

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of TYROBP mRNA

NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295

G

U2 small nuclear RNA auxiliary factor 1

decreases expression

dibenzo(a,l)pyrene results in decreased expression of U2AF1 mRNA

NCBI chr21:43,092,956...43,107,578
Ensembl chr21:43,092,956...43,107,570

G

ubiquitin D

decreases expression

dibenzo(a,l)pyrene results in decreased expression of UBD mRNA

NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732

G

ubiquitin conjugating enzyme E2 A

multiple interactions

[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of UBE2A mRNA

NCBI chr X:119,574,563...119,584,423
Ensembl chr X:119,474,802...119,591,083

G

ubiquitin conjugating enzyme E2 D3

decreases expression

dibenzo(a,l)pyrene results in decreased expression of UBE2D3 mRNA

NCBI chr 4:102,794,383...102,868,895
Ensembl chr 4:102,794,383...102,868,896

G

UDP-glucose ceramide glucosyltransferase

multiple interactions

[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of UGCG mRNA

NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369

G

UDP glucuronosyltransferase family 1 member A1

increases glycosylation

UGT1A1 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300

G

UDP glucuronosyltransferase family 1 member A10

increases glycosylation

UGT1A10 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300

G

UDP glucuronosyltransferase family 1 member A4

increases glycosylation

UGT1A4 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 2:233,718,736...233,773,300
Ensembl chr 2:233,718,736...233,773,300

G

UDP glucuronosyltransferase family 1 member A6

increases expression
multiple interactions

dibenzo(a,l)pyrene results in increased expression of UGT1A6 mRNA
[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A6 mRNA

NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300

G

UDP glucuronosyltransferase family 1 member A7

multiple interactions
increases glycosylation

[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of UGT1A7 mRNA
UGT1A7 protein results in increased glycosylation of dibenzo(a,l)pyrene

PMID:15566942 PMID:21780761

NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300

G

UDP glucuronosyltransferase family 1 member A8

increases glycosylation

UGT1A8 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300

G

UDP glucuronosyltransferase family 1 member A9

increases glycosylation

UGT1A9 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300

G

UDP glucuronosyltransferase family 2 member B7

increases glycosylation

UGT2B7 protein results in increased glycosylation of dibenzo(a,l)pyrene

NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987

G

UV radiation resistance associated

increases expression

dibenzo(a,l)pyrene results in increased expression of UVRAG mRNA

NCBI chr11:75,815,210...76,144,232
Ensembl chr11:75,815,210...76,144,232

G

vimentin

decreases expression

dibenzo(a,l)pyrene results in decreased expression of VIM mRNA

NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593

G

von Willebrand factor A domain containing 3B

increases expression

dibenzo(a,l)pyrene results in increased expression of VWA3B mRNA

NCBI chr 2:98,087,167...98,330,616
Ensembl chr 2:98,087,116...98,313,299

G

WD repeat domain 73

decreases expression

dibenzo(a,l)pyrene results in decreased expression of WDR73 mRNA

NCBI chr15:84,639,285...84,654,283
Ensembl chr15:84,639,285...84,654,343

G

WAP four-disulfide core domain 21, pseudogene

increases expression

dibenzo(a,l)pyrene results in increased expression of WFDC21 mRNA

NCBI chr17:60,083,566...60,088,467
Ensembl chr17:60,085,109...60,088,286

G

YES proto-oncogene 1, Src family tyrosine kinase

decreases expression

dibenzo(a,l)pyrene results in decreased expression of YES1 mRNA

NCBI chr18:721,588...812,753
Ensembl chr18:721,588...812,546

G

Yip1 domain family member 4

affects expression

dibenzo(a,l)pyrene affects the expression of YIPF4 mRNA

NCBI chr 2:32,277,904...32,316,594
Ensembl chr 2:32,277,904...32,316,594

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

decreases expression

dibenzo(a,l)pyrene results in decreased expression of YWHAG mRNA

NCBI chr 7:76,326,799...76,358,991
Ensembl chr 7:76,326,799...76,358,991

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

decreases expression

dibenzo(a,l)pyrene results in decreased expression of YWHAH mRNA

NCBI chr22:31,944,535...31,957,603
Ensembl chr22:31,944,522...31,957,603

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

decreases expression

dibenzo(a,l)pyrene results in decreased expression of YWHAQ mRNA

NCBI chr 2:9,583,967...9,630,997
Ensembl chr 2:9,583,967...9,630,997

G

zinc finger and BTB domain containing 7B

increases expression

dibenzo(a,l)pyrene results in increased expression of ZBTB7B mRNA

NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523

G

zinc finger CCCH-type containing 18

decreases expression

dibenzo(a,l)pyrene results in decreased expression of ZC3H18 mRNA

NCBI chr16:88,570,403...88,631,964
Ensembl chr16:88,570,403...88,631,964

G

zinc finger protein 878

increases expression

dibenzo(a,l)pyrene results in increased expression of ZFP958 mRNA

NCBI chr19:12,043,602...12,052,961
Ensembl chr19:12,043,805...12,052,961

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26089
role	26005
biological role	25984
aetiopathogenetic role	24624
genotoxin	20144
mutagen	19901
dibenzo[a,l]pyrene	365
Path 2
Term	Annotations
CHEBI ontology	26089
subatomic particle	26064
composite particle	26064
hadron	26064
baryon	26064
nucleon	26016
atomic nucleus	26064
atom	26064
main group element atom	25891
main group molecular entity	25891
s-block molecular entity	25200
hydrogen molecular entity	24793
hydrides	22993
organic hydride	21950
organic fundamental parent	21950
hydrocarbon	21374
cyclic hydrocarbon	20012
arene	19992
polycyclic arene	19680
ortho- and peri-fused polycyclic arene	18737
dibenzo[a,l]pyrene	365

paths to the root