U2AF1 (U2 small nuclear RNA auxiliary factor 1) - Rat Genome Database

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Gene: U2AF1 (U2 small nuclear RNA auxiliary factor 1) Homo sapiens
Analyze
Symbol: U2AF1
Name: U2 small nuclear RNA auxiliary factor 1
RGD ID: 1349504
HGNC Page HGNC:12453
Description: Enables RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2AF complex and catalytic step 2 spliceosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DKFZp313J1712; FP793; RN; RNU2AF1; splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein; U2AF35; U2AFBP
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC441722  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,092,956 - 43,107,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,092,956 - 43,107,570 (-)EnsemblGRCh38hg38GRCh38
GRCh372144,513,066 - 44,527,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,386,135 - 43,400,757 (-)NCBINCBI36Build 36hg18NCBI36
Build 342143,386,135 - 43,400,703NCBI
Celera2129,665,729 - 29,680,351 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2129,931,179 - 29,945,801 (-)NCBIHuRef
CHM1_12144,073,930 - 44,088,542 (-)NCBICHM1_1
T2T-CHM13v2.02141,484,016 - 41,498,649 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
mRNA processing  (IEA,TAS)
mRNA splicing, via spliceosome  (IBA,IC,IEA,NAS)
RNA splicing  (IEA,TAS)

Cellular Component
Cajal body  (TAS)
catalytic step 2 spliceosome  (IDA)
nuclear speck  (IEA,ISS)
nucleoplasm  (IDA,TAS)
nucleus  (IEA)
spliceosomal complex  (IBA,IDA,IEA,IPI)
U2AF complex  (IBA,IDA,IEA,IPI)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
Additional References at PubMed
PMID:1388271   PMID:1824937   PMID:2531895   PMID:7956352   PMID:8261509   PMID:8647433   PMID:8660980   PMID:8816452   PMID:9016565   PMID:9237760   PMID:9472028   PMID:9528748  
PMID:9645944   PMID:9671485   PMID:9671816   PMID:9731529   PMID:9799243   PMID:10830953   PMID:11060040   PMID:11118443   PMID:11448987   PMID:11500380   PMID:11533230   PMID:11551507  
PMID:11604503   PMID:11724776   PMID:11830556   PMID:11991638   PMID:12226669   PMID:12234937   PMID:12297299   PMID:12477932   PMID:12777385   PMID:14702039   PMID:15096518   PMID:15146077  
PMID:15474994   PMID:15489334   PMID:15652350   PMID:15899895   PMID:15950937   PMID:16014633   PMID:16043505   PMID:16189514   PMID:16712791   PMID:16809543   PMID:16855028   PMID:16940179  
PMID:17081983   PMID:17207965   PMID:17332742   PMID:17353931   PMID:17577209   PMID:17643375   PMID:18029348   PMID:18211889   PMID:18285458   PMID:18559666   PMID:19738201   PMID:20467437  
PMID:20514852   PMID:20696395   PMID:21081503   PMID:21145461   PMID:21424732   PMID:21460037   PMID:21516116   PMID:21873635   PMID:21907836   PMID:21988832   PMID:22158538   PMID:22174317  
PMID:22323480   PMID:22325350   PMID:22365833   PMID:22389253   PMID:22658674   PMID:22681889   PMID:22939629   PMID:22990118   PMID:23029227   PMID:23151878   PMID:23184937   PMID:23280334  
PMID:23335386   PMID:23455924   PMID:23602568   PMID:23775717   PMID:23861105   PMID:24097336   PMID:24241536   PMID:24389012   PMID:24457600   PMID:24498085   PMID:24711643   PMID:24722188  
PMID:24912190   PMID:24999758   PMID:25231745   PMID:25267526   PMID:25271374   PMID:25311244   PMID:25315684   PMID:25326705   PMID:25343990   PMID:25412851   PMID:25416956   PMID:25437307  
PMID:25665578   PMID:25921289   PMID:25959826   PMID:25964599   PMID:26264872   PMID:26344197   PMID:26472758   PMID:26496610   PMID:26508027   PMID:26641092   PMID:26725010   PMID:26760575  
PMID:26777405   PMID:26871637   PMID:27025967   PMID:27049334   PMID:27058230   PMID:27184077   PMID:27248496   PMID:27435003   PMID:27566151   PMID:27602765   PMID:27639445   PMID:27684187  
PMID:27776121   PMID:27799531   PMID:28067246   PMID:28186131   PMID:28302793   PMID:28372848   PMID:28436936   PMID:28514442   PMID:28515276   PMID:28712289   PMID:28893951   PMID:28938223  
PMID:28973437   PMID:28977666   PMID:29057546   PMID:29229926   PMID:29298432   PMID:29321554   PMID:29331416   PMID:29395067   PMID:29478914   PMID:29511261   PMID:29516544   PMID:29535431  
PMID:29649018   PMID:29777862   PMID:29802200   PMID:29845934   PMID:29892012   PMID:29934401   PMID:29955894   PMID:29991672   PMID:30152885   PMID:30194306   PMID:30334576   PMID:30804502  
PMID:30842218   PMID:30846499   PMID:30890647   PMID:30940648   PMID:30948266   PMID:31011167   PMID:31048545   PMID:31091453   PMID:31124956   PMID:31144421   PMID:31363146   PMID:31365120  
PMID:31504847   PMID:31586073   PMID:31605415   PMID:31640799   PMID:31685992   PMID:31694235   PMID:31754743   PMID:31796584   PMID:31826693   PMID:31836708   PMID:31992135   PMID:32023759  
PMID:32027245   PMID:32041737   PMID:32116123   PMID:32129710   PMID:32150510   PMID:32249768   PMID:32296183   PMID:32343311   PMID:32358566   PMID:32640226   PMID:32780723   PMID:32814053  
PMID:32958768   PMID:33022573   PMID:33122737   PMID:33137094   PMID:33226137   PMID:33239621   PMID:33274830   PMID:33283729   PMID:33306668   PMID:33314767   PMID:33347855   PMID:33477033  
PMID:33545068   PMID:33596420   PMID:33658012   PMID:33729478   PMID:33930289   PMID:33961781   PMID:34079125   PMID:34133714   PMID:34183647   PMID:34185411   PMID:34215620   PMID:34316702  
PMID:34373451   PMID:34520118   PMID:34581783   PMID:34650049   PMID:34893123   PMID:34896936   PMID:35271311   PMID:35303483   PMID:35434831   PMID:35446349   PMID:35509820   PMID:35563538  
PMID:35676246   PMID:35819319   PMID:35850772   PMID:35896951   PMID:35914814   PMID:35944360   PMID:36057605   PMID:36114006   PMID:36123327   PMID:36129843   PMID:36215168   PMID:36244648  
PMID:36339263   PMID:36373674   PMID:36424410   PMID:36526897   PMID:36574265   PMID:36586169   PMID:36779763   PMID:37487637   PMID:37591942   PMID:37616343   PMID:37665761   PMID:37735430  
PMID:37827155   PMID:37866880   PMID:37975232   PMID:38088204   PMID:38113892   PMID:38172120  


Genomics

Comparative Map Data
U2AF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,092,956 - 43,107,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,092,956 - 43,107,570 (-)EnsemblGRCh38hg38GRCh38
GRCh372144,513,066 - 44,527,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,386,135 - 43,400,757 (-)NCBINCBI36Build 36hg18NCBI36
Build 342143,386,135 - 43,400,703NCBI
Celera2129,665,729 - 29,680,351 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2129,931,179 - 29,945,801 (-)NCBIHuRef
CHM1_12144,073,930 - 44,088,542 (-)NCBICHM1_1
T2T-CHM13v2.02141,484,016 - 41,498,649 (-)NCBIT2T-CHM13v2.0
U2af1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391731,866,055 - 31,878,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1731,866,055 - 31,877,866 (-)EnsemblGRCm39 Ensembl
GRCm381731,647,081 - 31,659,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,647,081 - 31,658,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,784,027 - 31,795,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361731,375,793 - 31,387,425 (-)NCBIMGSCv36mm8
Celera1732,564,314 - 32,575,985 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.02NCBI
U2af1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8209,744,206 - 9,755,146 (-)NCBIGRCr8
mRatBN7.2209,742,904 - 9,753,840 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl209,742,905 - 9,753,832 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2010,444,482 - 10,455,368 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0209,805,670 - 9,816,556 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02010,274,178 - 10,285,068 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02010,396,652 - 10,407,564 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,396,621 - 10,407,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,582,585 - 12,593,487 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2011,256,755 - 11,267,643 (-)NCBICelera
Cytogenetic Map20p12NCBI
U2af1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540738,895,711 - 38,909,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540738,895,741 - 38,909,820 (+)NCBIChiLan1.0ChiLan1.0
U2AF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22239,148,192 - 39,162,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12134,001,084 - 34,015,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02129,399,601 - 29,414,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12142,707,738 - 42,719,086 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2142,707,738 - 42,719,086 (-)Ensemblpanpan1.1panPan2
U2AF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,263,265 - 37,276,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,412,908 - 36,426,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03136,805,348 - 36,818,994 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3136,805,359 - 36,818,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13136,672,392 - 36,686,045 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03136,651,910 - 36,665,348 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,149,648 - 37,163,284 (-)NCBIUU_Cfam_GSD_1.0
U2af1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497136,500,032 - 36,511,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500958,256 - 967,829 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936500937,537 - 967,791 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
U2AF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13206,244,773 - 206,257,702 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113206,244,772 - 206,257,697 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103219520
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1286,949,910 - 86,964,655 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl286,950,056 - 86,964,579 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605414,950,099 - 14,964,875 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
U2af1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474527,647,597 - 27,660,809 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474527,647,672 - 27,660,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in U2AF1
6 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 21q22.3(chr21:42232926-46670405)x1 copy number loss See cases [RCV000050746] Chr21:42232926..46670405 [GRCh38]
Chr21:43653036..48090317 [GRCh37]
Chr21:42526105..46914745 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000050445] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 21q22.3(chr21:41285201-46670405)x1 copy number loss See cases [RCV000051022] Chr21:41285201..46670405 [GRCh38]
Chr21:42657128..48090317 [GRCh37]
Chr21:41578998..46914745 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:35027972-46670405)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052836]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052836]|See cases [RCV000052836] Chr21:35027972..46670405 [GRCh38]
Chr21:36400269..48090317 [GRCh37]
Chr21:35322139..46914745 [NCBI36]
Chr21:21q22.12-22.3		 pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:38273492-46670405)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052838]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052838]|See cases [RCV000052838] Chr21:38273492..46670405 [GRCh38]
Chr21:39645414..48090317 [GRCh37]
Chr21:38567284..46914745 [NCBI36]
Chr21:21q22.13-22.3		 pathogenic
GRCh38/hg38 21q22.2-22.3(chr21:40127825-46670546)x1 copy number loss See cases [RCV000052839] Chr21:40127825..46670546 [GRCh38]
Chr21:41499752..48090458 [GRCh37]
Chr21:40421622..46914886 [NCBI36]
Chr21:21q22.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053042] Chr21:7749532..46623792 [GRCh38]
Chr21:14595524..48043704 [GRCh37]
Chr21:13517395..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053043] Chr21:7749532..46623792 [GRCh38]
Chr21:14629063..48043704 [GRCh37]
Chr21:13550934..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670546)x3 copy number gain See cases [RCV000053045] Chr21:7749532..46670546 [GRCh38]
Chr21:15499647..48090458 [GRCh37]
Chr21:14421518..46914886 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053065] Chr21:7749532..46661140 [GRCh38]
Chr21:15499647..48081052 [GRCh37]
Chr21:14421518..46905480 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053067] Chr21:7749532..46661140 [GRCh38]
Chr21:15499847..48081052 [GRCh37]
Chr21:14421718..46905480 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053068] Chr21:7749532..46670405 [GRCh38]
Chr21:20655360..48090317 [GRCh37]
Chr21:19577231..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053069] Chr21:7749532..46670405 [GRCh38]
Chr21:34423268..48090317 [GRCh37]
Chr21:33345138..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053039] Chr21:7749532..46623792 [GRCh38]
Chr21:14524963..48043704 [GRCh37]
Chr21:13446834..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653090)x3 copy number gain See cases [RCV000053040] Chr21:7749532..46653090 [GRCh38]
Chr21:14539679..48073002 [GRCh37]
Chr21:13461550..46897430 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.3(chr21:43071168-46670405)x1 copy number loss See cases [RCV000133675] Chr21:43071168..46670405 [GRCh38]
Chr21:44491278..48090317 [GRCh37]
Chr21:43364347..46914745 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653084)x3 copy number gain See cases [RCV000134727] Chr21:7749532..46653084 [GRCh38]
Chr21:15485038..48072996 [GRCh37]
Chr21:14406909..46897424 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46649831)x3 copy number gain See cases [RCV000134509] Chr21:7749532..46649831 [GRCh38]
Chr21:14577835..48069743 [GRCh37]
Chr21:13499706..46894171 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134119] Chr21:7749532..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.11-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000135310] Chr21:7749532..46670346 [GRCh38]
Chr21:34111831..48090258 [GRCh37]
Chr21:33033702..46914686 [NCBI36]
Chr21:21q22.11-22.3		 pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:36206067-46670405)x3 copy number gain See cases [RCV000134972] Chr21:36206067..46670405 [GRCh38]
Chr21:37578365..48090317 [GRCh37]
Chr21:36500235..46914745 [NCBI36]
Chr21:21q22.12-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46664250)x3 copy number gain See cases [RCV000134836] Chr21:7749532..46664250 [GRCh38]
Chr21:15485038..48084162 [GRCh37]
Chr21:14406909..46908590 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134842] Chr21:7749532..46670440 [GRCh38]
Chr21:15513244..48090352 [GRCh37]
Chr21:14435115..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46660999)x3 copy number gain See cases [RCV000135448] Chr21:7749532..46660999 [GRCh38]
Chr21:15499847..48080911 [GRCh37]
Chr21:14421718..46905339 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:36519173-46670405)x3 copy number gain See cases [RCV000136142] Chr21:36519173..46670405 [GRCh38]
Chr21:37891471..48090317 [GRCh37]
Chr21:36813341..46914745 [NCBI36]
Chr21:21q22.13-22.3		 pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:34789953-46636538)x1 copy number loss See cases [RCV000136828] Chr21:34789953..46636538 [GRCh38]
Chr21:36162250..48056450 [GRCh37]
Chr21:35084120..46880878 [NCBI36]
Chr21:21q22.12-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137255] Chr21:7749532..46671060 [GRCh38]
Chr21:35319225..48090972 [GRCh37]
Chr21:34241095..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137337] Chr21:7749532..46671060 [GRCh38]
Chr21:10697897..48090972 [GRCh37]
Chr21:1..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.3(chr21:41733640-46671060)x1 copy number loss See cases [RCV000137341] Chr21:41733640..46671060 [GRCh38]
Chr21:43153800..48090972 [GRCh37]
Chr21:42026869..46915400 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138216] Chr21:7749532..46671060 [GRCh38]
Chr21:10944001..48090972 [GRCh37]
Chr21:9965872..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.13-22.3(chr21:37669628-46671060)x1 copy number loss See cases [RCV000138096] Chr21:37669628..46671060 [GRCh38]
Chr21:39041930..48090972 [GRCh37]
Chr21:37963800..46915400 [NCBI36]
Chr21:21q22.13-22.3		 pathogenic
GRCh38/hg38 21q22.12-22.3(chr21:36066991-46671060)x3 copy number gain See cases [RCV000138164] Chr21:36066991..46671060 [GRCh38]
Chr21:37439289..48090972 [GRCh37]
Chr21:36361159..46915400 [NCBI36]
Chr21:21q22.12-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138436] Chr21:7749532..46671060 [GRCh38]
Chr21:15451032..48090972 [GRCh37]
Chr21:14372903..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic|conflicting data from submitters
GRCh38/hg38 21q22.2-22.3(chr21:40296025-46670440)x1 copy number loss See cases [RCV000139158] Chr21:40296025..46670440 [GRCh38]
Chr21:41667952..48090352 [GRCh37]
Chr21:40589822..46914780 [NCBI36]
Chr21:21q22.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000140103] Chr21:7749532..46670346 [GRCh38]
Chr21:14577894..48090258 [GRCh37]
Chr21:13499765..46914686 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46698247)x3 copy number gain See cases [RCV000141346] Chr21:7749532..46698247 [GRCh38]
Chr21:14577835..48118159 [GRCh37]
Chr21:13499706..46942587 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q21.3-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000141827] Chr21:7749532..46677460 [GRCh38]
Chr21:28285299..48097372 [GRCh37]
Chr21:27207170..46921800 [NCBI36]
Chr21:21q21.3-22.3		 uncertain significance
GRCh38/hg38 21q22.2-22.3(chr21:38816399-46677460)x1 copy number loss See cases [RCV000142311] Chr21:38816399..46677460 [GRCh38]
Chr21:40188323..48097372 [GRCh37]
Chr21:39110193..46921800 [NCBI36]
Chr21:21q22.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7817158-46670440)x1 copy number loss See cases [RCV000142427] Chr21:7817158..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.2-22.3(chr21:39375937-44246148)x1 copy number loss See cases [RCV000142650] Chr21:39375937..44246148 [GRCh38]
Chr21:40747863..45666031 [GRCh37]
Chr21:39669733..44490459 [NCBI36]
Chr21:21q22.2-22.3		 pathogenic
GRCh38/hg38 21q22.3(chr21:42913213-46670405)x1 copy number loss See cases [RCV000142600] Chr21:42913213..46670405 [GRCh38]
Chr21:44333323..48090317 [GRCh37]
Chr21:43206392..46914745 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143376] Chr21:7749532..46677460 [GRCh38]
Chr21:15006458..48097372 [GRCh37]
Chr21:13928329..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460) copy number gain See cases [RCV000143160] Chr21:7749532..46677460 [GRCh38]
Chr21:14386013..48097372 [GRCh37]
Chr21:13307884..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q22.3(chr21:42129699-46671060)x1 copy number loss See cases [RCV000143335] Chr21:42129699..46671060 [GRCh38]
Chr21:43549809..48090972 [GRCh37]
Chr21:42422878..46915400 [NCBI36]
Chr21:21q22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143120] Chr21:7749532..46677460 [GRCh38]
Chr21:15006457..48097372 [GRCh37]
Chr21:13928328..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000148131] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:44264486-45945979)x1 copy number loss See cases [RCV000240216] Chr21:44264486..45945979 [GRCh37]
Chr21:21q22.3		 uncertain significance
Single allele duplication not provided [RCV000768458] Chr21:43010560..48093051 [GRCh37]
Chr21:21q22.3		 likely pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15538655-48080926)x1 copy number loss See cases [RCV000239948] Chr21:15538655..48080926 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:39841248-44652723)x3 copy number gain See cases [RCV000239953] Chr21:39841248..44652723 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15410701-48090317)x3 copy number gain See cases [RCV000240397] Chr21:15410701..48090317 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
NC_000021.8:g.(?_43892908)_(45629566_?)dup duplication Primary ciliary dyskinesia [RCV000552378] Chr21:43892908..45629566 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q22.3(chr21:43268694-48097372)x1 copy number loss See cases [RCV000446372] Chr21:43268694..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43598607-48097372)x1 copy number loss See cases [RCV000447618] Chr21:43598607..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
NM_006758.3(U2AF1):c.101C>A (p.Ser34Tyr) single nucleotide variant Acute myeloid leukemia [RCV000422842]|Lung adenocarcinoma [RCV000442074]|Malignant neoplasm of body of uterus [RCV000433981]|Myelodysplastic syndrome [RCV000427463]|Neoplasm of uterine cervix [RCV000444842]|Pancreatic adenocarcinoma [RCV000440542]|Squamous cell carcinoma of the head and neck [RCV000431623]|Transitional cell carcinoma of the bladder [RCV000423738]|Uterine carcinosarcoma [RCV000433988] Chr21:43104346 [GRCh38]
Chr21:44524456 [GRCh37]
Chr21:21q22.3		 likely pathogenic
NM_006758.3(U2AF1):c.470A>C (p.Gln157Pro) single nucleotide variant Acute myeloid leukemia [RCV000427799]|Myelodysplastic syndrome [RCV000438020]|not provided [RCV003321588] Chr21:43094667 [GRCh38]
Chr21:44514777 [GRCh37]
Chr21:21q22.3		 likely pathogenic|not provided
NM_006758.3(U2AF1):c.470A>G (p.Gln157Arg) single nucleotide variant Acute myeloid leukemia [RCV000444682] Chr21:43094667 [GRCh38]
Chr21:44514777 [GRCh37]
Chr21:21q22.3		 likely pathogenic
NM_006758.3(U2AF1):c.101C>T (p.Ser34Phe) single nucleotide variant Acute myeloid leukemia [RCV000424461]|Lung adenocarcinoma [RCV000429164]|Malignant neoplasm of body of uterus [RCV000439423]|Myelodysplastic syndrome [RCV000435634]|Neoplasm of uterine cervix [RCV000429358]|Pancreatic adenocarcinoma [RCV000418032]|Squamous cell carcinoma of the head and neck [RCV000419121]|Transitional cell carcinoma of the bladder [RCV000417769]|Uterine carcinosarcoma [RCV000440465] Chr21:43104346 [GRCh38]
Chr21:44524456 [GRCh37]
Chr21:21q22.3		 likely pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42410406-48097372)x1 copy number loss See cases [RCV000448694] Chr21:42410406..48097372 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14771770-48080867)x3 copy number gain See cases [RCV000447884] Chr21:14771770..48080867 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-44827632)x3 copy number gain See cases [RCV000448199] Chr21:15006457..44827632 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372)x3 copy number gain See cases [RCV000447729] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain See cases [RCV000447749] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43498966-48097372)x1 copy number loss See cases [RCV000512071] Chr21:43498966..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.13-22.3(chr21:38699545-48097372)x1 copy number loss See cases [RCV000510684] Chr21:38699545..48097372 [GRCh37]
Chr21:21q22.13-22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:41254101-48097372)x1 copy number loss See cases [RCV000511808] Chr21:41254101..48097372 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006458-48097372) copy number gain See cases [RCV000511589] Chr21:15006458..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.13-22.3(chr21:37914123-48097372)x1 copy number loss See cases [RCV000510798] Chr21:37914123..48097372 [GRCh37]
Chr21:21q22.13-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43687353-48097372)x1 copy number loss not provided [RCV000684163] Chr21:43687353..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42335622-48097372)x1 copy number loss not provided [RCV000684165] Chr21:42335622..48097372 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
NC_000021.8:g.(?_43892908)_(44592410_?)dup duplication Primary ciliary dyskinesia [RCV000708153] Chr21:42472798..43172300 [GRCh38]
Chr21:43892908..44592410 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21p11.2-q22.3(chr21:10827533-48100155)x3 copy number gain not provided [RCV000741419] Chr21:10827533..48100155 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10699330-48117896)x3 copy number gain not provided [RCV000741413] Chr21:10699330..48117896 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10704198-48117896)x3 copy number gain not provided [RCV000741415] Chr21:10704198..48117896 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10824040-48090629)x3 copy number gain not provided [RCV000741418] Chr21:10824040..48090629 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:41537095-46914745) copy number loss not provided [RCV000767626] Chr21:41537095..46914745 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
NC_000021.8:g.(?_43892908)_(45629566_?)del deletion Developmental and epileptic encephalopathy, 30 [RCV001346941]|Primary ciliary dyskinesia [RCV000802591] Chr21:43892908..45629566 [GRCh37]
Chr21:21q22.3		 pathogenic|uncertain significance|no classifications from unflagged records
NC_000021.8:g.(?_43792871)_(46330697_?)dup duplication not provided [RCV001031286] Chr21:43792871..46330697 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q22.3(chr21:43822539-44974001)x3 copy number gain not provided [RCV001007139] Chr21:43822539..44974001 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q22.13-22.3(chr21:39410438-45171756)x1 copy number loss not provided [RCV001007132] Chr21:39410438..45171756 [GRCh37]
Chr21:21q22.13-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV000846937] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:44310057-47503155)x1 copy number loss not provided [RCV000847671] Chr21:44310057..47503155 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43756585-46240105)x1 copy number loss not provided [RCV000849014] Chr21:43756585..46240105 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42046399-45109188)x1 copy number loss not provided [RCV002472503] Chr21:42046399..45109188 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43472147-48097372)x1 copy number loss not provided [RCV001007138] Chr21:43472147..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42044877-48100155)x3 copy number gain See cases [RCV001007433] Chr21:42044877..48100155 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14420615-48080926)x3 copy number gain Complete trisomy 21 syndrome [RCV002284306] Chr21:14420615..48080926 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14629063-48090317)x3 copy number gain See cases [RCV001263025] Chr21:14629063..48090317 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:44526182-44601620)x1 copy number loss not provided [RCV001834306] Chr21:44526182..44601620 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21p13-q22.3(chr21:1-48129895)x3 copy number gain See cases [RCV001780078] Chr21:1..48129895 [GRCh37]
Chr21:21p13-q22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:42679089-48097372) copy number loss Delayed speech and language development [RCV002280704] Chr21:42679089..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15041209-48097372) copy number gain not specified [RCV002052724] Chr21:15041209..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.2-22.3(chr21:42410406-48097372) copy number loss not specified [RCV002052739] Chr21:42410406..48097372 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV001829203] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372) copy number gain not specified [RCV002052723] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
NC_000021.8:g.(?_43160998)_(47865240_?)dup duplication Cataract 9 multiple types [RCV001913783]|Developmental and epileptic encephalopathy, 30 [RCV003120744]|Primary ciliary dyskinesia [RCV001913782] Chr21:43160998..47865240 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372) copy number gain not specified [RCV002052725] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
NC_000021.8:g.(?_43160998)_(47865240_?)del deletion HYPERHOMOCYSTEINEMIA, THROMBOTIC, CBS-RELATED [RCV001956307] Chr21:43160998..47865240 [GRCh37]
Chr21:21q22.3		 pathogenic
NC_000021.8:g.(?_44473990)_(47865240_?)dup duplication not provided [RCV002011965] Chr21:44473990..47865240 [GRCh37]
Chr21:21q22.3		 uncertain significance
NC_000021.8:g.(?_43160998)_(47754702_?)del deletion Developmental and epileptic encephalopathy, 30 [RCV003119312]|Progressive myoclonic epilepsy [RCV003119311] Chr21:43160998..47754702 [GRCh37]
Chr21:21q22.3		 pathogenic|uncertain significance
NM_006758.3(U2AF1):c.643G>A (p.Gly215Ser) single nucleotide variant not specified [RCV004171816] Chr21:43093182 [GRCh38]
Chr21:44513292 [GRCh37]
Chr21:21q22.3		 uncertain significance
NM_006758.3(U2AF1):c.637G>A (p.Gly213Ser) single nucleotide variant not specified [RCV004342827] Chr21:43093188 [GRCh38]
Chr21:44513298 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q22.2-22.3(chr21:40681179-48097372)x1 copy number loss not provided [RCV003483381] Chr21:40681179..48097372 [GRCh37]
Chr21:21q22.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006458-45674637)x3 copy number gain not provided [RCV003485218] Chr21:15006458..45674637 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q22.11-22.3(chr21:33015681-48097372)x3 copy number gain not provided [RCV003485222] Chr21:33015681..48097372 [GRCh37]
Chr21:21q22.11-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43687354-48097372)x3 copy number gain not provided [RCV003485225] Chr21:43687354..48097372 [GRCh37]
Chr21:21q22.3		 likely pathogenic
GRCh37/hg19 21q22.3(chr21:43744362-44784657)x3 copy number gain not provided [RCV003485226] Chr21:43744362..44784657 [GRCh37]
Chr21:21q22.3		 uncertain significance
GRCh37/hg19 21q22.3(chr21:43603041-48097372)x1 copy number loss not specified [RCV003986150] Chr21:43603041..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15023401-48097372)x3 copy number gain not specified [RCV003986160] Chr21:15023401..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q21.3-22.3(chr21:26929299-48097372)x3 copy number gain not specified [RCV003986152] Chr21:26929299..48097372 [GRCh37]
Chr21:21q21.3-22.3		 pathogenic
GRCh37/hg19 21q22.3(chr21:43369956-48097372)x1 copy number loss not specified [RCV003986155] Chr21:43369956..48097372 [GRCh37]
Chr21:21q22.3		 pathogenic
GRCh37/hg19 21q22.11-22.3(chr21:34092685-48097372)x3 copy number gain not specified [RCV003986158] Chr21:34092685..48097372 [GRCh37]
Chr21:21q22.11-22.3		 pathogenic
GRCh37/hg19 21q22.12-22.3(chr21:35872675-48097372)x1 copy number loss not specified [RCV003986157] Chr21:35872675..48097372 [GRCh37]
Chr21:21q22.12-22.3		 pathogenic
GRCh37/hg19 21q21.3-22.3(chr21:30685776-48097372)x3 copy number gain not specified [RCV003986149] Chr21:30685776..48097372 [GRCh37]
Chr21:21q21.3-22.3		 pathogenic
NM_006758.3(U2AF1):c.99C>T (p.Cys33=) single nucleotide variant U2AF1-related condition [RCV003963892] Chr21:43104348 [GRCh38]
Chr21:44524458 [GRCh37]
Chr21:21q22.3		 benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1336
Count of miRNA genes:693
Interacting mature miRNAs:792
Transcripts:ENST00000291552, ENST00000380276, ENST00000398137, ENST00000459639, ENST00000463599, ENST00000464750, ENST00000468039, ENST00000471250, ENST00000475639, ENST00000478282, ENST00000486519, ENST00000496462
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-M96982  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371535,385,075 - 35,385,259UniSTSGRCh37
Build 361533,172,367 - 33,172,551RGDNCBI36
Celera1512,144,360 - 12,144,544RGD
Cytogenetic Map15q14UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map21q22.3UniSTS
HuRef1512,230,308 - 12,230,492UniSTS
GeneMap99-GB4 RH Map1588.15UniSTS
RH80644  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372144,513,089 - 44,513,267UniSTSGRCh37
Build 362143,386,158 - 43,386,336RGDNCBI36
Celera2129,665,752 - 29,665,930RGD
Cytogenetic Map21q22.3UniSTS
HuRef2129,931,202 - 29,931,380UniSTS
D11S3537  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371171,991,762 - 71,991,895UniSTSGRCh37
GRCh372144,514,867 - 44,515,642UniSTSGRCh37
Build 361171,669,410 - 71,669,543RGDNCBI36
Celera2129,667,530 - 29,668,305UniSTS
Celera1169,293,173 - 69,293,306RGD
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map21q22.3UniSTS
HuRef2129,932,980 - 29,933,755UniSTS
HuRef1168,284,859 - 68,284,992UniSTS
STS-W74700  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372144,516,530 - 44,516,740UniSTSGRCh37
Build 362143,389,599 - 43,389,809RGDNCBI36
Celera2129,669,193 - 29,669,403RGD
Cytogenetic Map21q22.3UniSTS
HuRef2129,934,643 - 29,934,853UniSTS
TNG Radiation Hybrid Map2117851.0UniSTS
GeneMap99-GB4 RH Map21226.39UniSTS
NCBI RH Map21387.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 98 8 185 133 263 132 42 24 93 172 211 192 4 1 2 2
Low 2117 2046 1572 329 1131 160 4367 941 1935 181 1305 1927 181 1487 2484 4
Below cutoff 2064 3312 1130 468 1323 350 3265 2942 4520 149 862 520 118 704 2582

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001025204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017028468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024452131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054324841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB451244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF370386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ627978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK022152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK307560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP002085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB110007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M96982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000291552   ⟹   ENSP00000291552
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,107,570 (-)Ensembl
RefSeq Acc Id: ENST00000380276   ⟹   ENSP00000369629
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,107,565 (-)Ensembl
RefSeq Acc Id: ENST00000398137   ⟹   ENSP00000381205
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,957 - 43,107,578 (-)Ensembl
RefSeq Acc Id: ENST00000459639   ⟹   ENSP00000418705
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,105,252 (-)Ensembl
RefSeq Acc Id: ENST00000463599
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,095,702 - 43,104,476 (-)Ensembl
RefSeq Acc Id: ENST00000464750   ⟹   ENSP00000420672
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,107,524 (-)Ensembl
RefSeq Acc Id: ENST00000468039
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,100,453 - 43,101,907 (-)Ensembl
RefSeq Acc Id: ENST00000471250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,095,943 (-)Ensembl
RefSeq Acc Id: ENST00000475639
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,107,524 (-)Ensembl
RefSeq Acc Id: ENST00000478282
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,092,956 - 43,096,390 (-)Ensembl
RefSeq Acc Id: ENST00000486519   ⟹   ENSP00000489632
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,093,190 - 43,107,570 (-)Ensembl
RefSeq Acc Id: ENST00000496462
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2143,097,622 - 43,107,524 (-)Ensembl
RefSeq Acc Id: NM_001025203   ⟹   NP_001020374
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
GRCh372144,513,066 - 44,527,716 (-)NCBI
Build 362143,386,135 - 43,400,757 (-)NCBI Archive
HuRef2129,931,179 - 29,945,801 (-)ENTREZGENE
CHM1_12144,073,930 - 44,088,542 (-)NCBI
T2T-CHM13v2.02141,484,016 - 41,498,649 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001025204   ⟹   NP_001020375
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,570 (-)NCBI
GRCh372144,513,066 - 44,527,716 (-)NCBI
Build 362143,386,135 - 43,400,757 (-)NCBI Archive
HuRef2129,931,179 - 29,945,801 (-)ENTREZGENE
CHM1_12144,073,930 - 44,088,542 (-)NCBI
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006758   ⟹   NP_006749
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,570 (-)NCBI
GRCh372144,513,066 - 44,527,716 (-)NCBI
Build 362143,386,135 - 43,400,757 (-)NCBI Archive
HuRef2129,931,179 - 29,945,801 (-)ENTREZGENE
CHM1_12144,073,930 - 44,088,542 (-)NCBI
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011529743   ⟹   XP_011528045
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017028468   ⟹   XP_016883957
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452129   ⟹   XP_024307897
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452130   ⟹   XP_024307898
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024452131   ⟹   XP_024307899
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,092,956 - 43,107,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054324837   ⟹   XP_054180812
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
RefSeq Acc Id: XM_054324838   ⟹   XP_054180813
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
RefSeq Acc Id: XM_054324839   ⟹   XP_054180814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
RefSeq Acc Id: XM_054324840   ⟹   XP_054180815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
RefSeq Acc Id: XM_054324841   ⟹   XP_054180816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02141,484,016 - 41,498,641 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020374 (Get FASTA)   NCBI Sequence Viewer  
  NP_001020375 (Get FASTA)   NCBI Sequence Viewer  
  NP_006749 (Get FASTA)   NCBI Sequence Viewer  
  XP_011528045 (Get FASTA)   NCBI Sequence Viewer  
  XP_016883957 (Get FASTA)   NCBI Sequence Viewer  
  XP_024307897 (Get FASTA)   NCBI Sequence Viewer  
  XP_024307898 (Get FASTA)   NCBI Sequence Viewer  
  XP_024307899 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180812 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180813 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180814 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180815 (Get FASTA)   NCBI Sequence Viewer  
  XP_054180816 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36619 (Get FASTA)   NCBI Sequence Viewer  
  AAH01177 (Get FASTA)   NCBI Sequence Viewer  
  AAH01923 (Get FASTA)   NCBI Sequence Viewer  
  AAH05915 (Get FASTA)   NCBI Sequence Viewer  
  AAQ15222 (Get FASTA)   NCBI Sequence Viewer  
  BAA95534 (Get FASTA)   NCBI Sequence Viewer  
  BAG70058 (Get FASTA)   NCBI Sequence Viewer  
  CAF29556 (Get FASTA)   NCBI Sequence Viewer  
  CAH10401 (Get FASTA)   NCBI Sequence Viewer  
  EAX09501 (Get FASTA)   NCBI Sequence Viewer  
  EAX09502 (Get FASTA)   NCBI Sequence Viewer  
  EAX09503 (Get FASTA)   NCBI Sequence Viewer  
  EAX09504 (Get FASTA)   NCBI Sequence Viewer  
  EAX09505 (Get FASTA)   NCBI Sequence Viewer  
  EAX09506 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000291552
  ENSP00000291552.4
  ENSP00000369629
  ENSP00000369629.2
  ENSP00000418705
  ENSP00000418705.1
  ENSP00000420672.1
  ENSP00000489632.1
GenBank Protein Q01081 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_006749   ⟸   NM_006758
- Peptide Label: isoform a
- UniProtKB: Q701P4 (UniProtKB/Swiss-Prot),   Q71RF1 (UniProtKB/Swiss-Prot),   Q01081 (UniProtKB/Swiss-Prot),   B5BU08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020374   ⟸   NM_001025203
- Peptide Label: isoform b
- UniProtKB: B5BU08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020375   ⟸   NM_001025204
- Peptide Label: isoform c
- UniProtKB: Q01081 (UniProtKB/Swiss-Prot),   Q7Z780 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011528045   ⟸   XM_011529743
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016883957   ⟸   XM_017028468
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_024307897   ⟸   XM_024452129
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024307899   ⟸   XM_024452131
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024307898   ⟸   XM_024452130
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000291552   ⟸   ENST00000291552
RefSeq Acc Id: ENSP00000381205   ⟸   ENST00000398137
RefSeq Acc Id: ENSP00000420672   ⟸   ENST00000464750
RefSeq Acc Id: ENSP00000418705   ⟸   ENST00000459639
RefSeq Acc Id: ENSP00000489632   ⟸   ENST00000486519
RefSeq Acc Id: ENSP00000369629   ⟸   ENST00000380276
RefSeq Acc Id: XP_054180812   ⟸   XM_054324837
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054180813   ⟸   XM_054324838
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054180814   ⟸   XM_054324839
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054180815   ⟸   XM_054324840
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054180816   ⟸   XM_054324841
- Peptide Label: isoform X3
Protein Domains
C3H1-type   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0DN76-F1-model_v2 AlphaFold P0DN76 1-240 view protein structure
AF-Q01081-F1-model_v2 AlphaFold Q01081 1-240 view protein structure

Promoters
RGD ID:13602970
Promoter ID:EPDNEW_H27669
Type:initiation region
Name:U2AF1_1
Description:U2 small nuclear RNA auxiliary factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382143,107,554 - 43,107,614EPDNEW
RGD ID:6799615
Promoter ID:HG_KWN:41079
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000195547,   OTTHUMT00000195548
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,387,916 - 43,390,522 (-)MPROMDB
RGD ID:6815397
Promoter ID:HG_MRA:10236
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:AK023589
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,392,171 - 43,392,777 (-)MPROMDB
RGD ID:6799616
Promoter ID:HG_KWN:41080
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000195551
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,394,641 - 43,395,892 (-)MPROMDB
RGD ID:6799614
Promoter ID:HG_KWN:41081
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000195544,   OTTHUMT00000195549
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,397,691 - 43,399,377 (-)MPROMDB
RGD ID:6799408
Promoter ID:HG_KWN:41082
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001025203,   NM_001025204,   OTTHUMT00000195541,   OTTHUMT00000195545,   OTTHUMT00000195550,   UC002ZDC.1,   UC010GPI.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,400,676 - 43,401,712 (-)MPROMDB
RGD ID:6853166
Promoter ID:EP74404
Type:initiation region
Name:HS_U2AF1
Description:U2(RNU2) small nuclear RNA auxillary factor 1.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 362143,400,703 - 43,400,763EPD

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12453 AgrOrtholog
COSMIC U2AF1 COSMIC
Ensembl Genes ENSG00000160201 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000291552 ENTREZGENE
  ENST00000291552.9 UniProtKB/Swiss-Prot
  ENST00000380276 ENTREZGENE
  ENST00000380276.6 UniProtKB/Swiss-Prot
  ENST00000459639 ENTREZGENE
  ENST00000459639.5 UniProtKB/Swiss-Prot
  ENST00000464750.5 UniProtKB/Swiss-Prot
  ENST00000486519.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000160201 GTEx
HGNC ID HGNC:12453 ENTREZGENE
Human Proteome Map U2AF1 Human Proteome Map
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  U2AF_small UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
KEGG Report hsa:102724594 UniProtKB/Swiss-Prot
  hsa:7307 UniProtKB/Swiss-Prot
NCBI Gene 7307 ENTREZGENE
OMIM 191317 OMIM
PANTHER PTHR12620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPLICING FACTOR U2AF 35 KDA SUBUNIT-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37103 PharmGKB
PRINTS U2AUXFACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A1B0GW87_HUMAN UniProtKB/TrEMBL
  B5BU08 ENTREZGENE, UniProtKB/TrEMBL
  Q01081 ENTREZGENE
  Q701P4 ENTREZGENE
  Q71RF1 ENTREZGENE
  Q7Z780 ENTREZGENE, UniProtKB/TrEMBL
  U2AF1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q701P4 UniProtKB/Swiss-Prot
  Q71RF1 UniProtKB/Swiss-Prot