U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1) - Rat Genome Database

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Gene: U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1) Mus musculus
Analyze
Symbol: U2af1
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
RGD ID: 1622162
MGI Page MGI
Description: Enables RS domain binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nuclear speck. Is expressed in several structures, including central nervous system; genitourinary system; peripheral nervous system; sensory organ; and skeleton. Orthologous to human U2AF1 (U2 small nuclear RNA auxiliary factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2010107D16Rik; 35kD; 35kDa; splicing factor U2AF 35 kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF),35 kDa; U2 snRNP auxiliary factor small subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391731,866,055 - 31,878,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1731,866,055 - 31,877,866 (-)EnsemblGRCm39 Ensembl
GRCm381731,647,081 - 31,659,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,647,081 - 31,658,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,784,027 - 31,795,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361731,375,793 - 31,387,425 (-)NCBIMGSCv36mm8
Celera1732,564,314 - 32,575,985 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11707078   PMID:11739736   PMID:12466851   PMID:12466854   PMID:12466855   PMID:12477932   PMID:12520002  
PMID:12904583   PMID:14610273   PMID:15489334   PMID:15618518   PMID:15798186   PMID:16014633   PMID:16033648   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18287559   PMID:18758164  
PMID:18799693   PMID:19783846   PMID:21267068   PMID:21873635   PMID:24457600   PMID:25706610   PMID:25965570   PMID:26426291   PMID:27184077   PMID:28378742   PMID:29617656   PMID:30322915  
PMID:30333137   PMID:30457570   PMID:31504847   PMID:33378226   PMID:33414485   PMID:34034558   PMID:34203454   PMID:34469727   PMID:34546980   PMID:35012549   PMID:36922625   PMID:37591942  


Genomics

Comparative Map Data
U2af1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391731,866,055 - 31,878,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1731,866,055 - 31,877,866 (-)EnsemblGRCm39 Ensembl
GRCm381731,647,081 - 31,659,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1731,647,081 - 31,658,892 (-)EnsemblGRCm38mm10GRCm38
MGSCv371731,784,027 - 31,795,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361731,375,793 - 31,387,425 (-)NCBIMGSCv36mm8
Celera1732,564,314 - 32,575,985 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.02NCBI
U2AF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382143,092,956 - 43,107,578 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2143,092,956 - 43,107,570 (-)EnsemblGRCh38hg38GRCh38
GRCh372144,513,066 - 44,527,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,386,135 - 43,400,757 (-)NCBINCBI36Build 36hg18NCBI36
Build 342143,386,135 - 43,400,703NCBI
Celera2129,665,729 - 29,680,351 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2129,931,179 - 29,945,801 (-)NCBIHuRef
CHM1_12144,073,930 - 44,088,542 (-)NCBICHM1_1
T2T-CHM13v2.02141,484,016 - 41,498,649 (-)NCBIT2T-CHM13v2.0
U2af1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8209,744,206 - 9,755,146 (-)NCBIGRCr8
mRatBN7.2209,742,904 - 9,753,840 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl209,742,905 - 9,753,832 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2010,444,482 - 10,455,368 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0209,805,670 - 9,816,556 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02010,274,178 - 10,285,068 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02010,396,652 - 10,407,564 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,396,621 - 10,407,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02012,582,585 - 12,593,487 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2011,256,755 - 11,267,643 (-)NCBICelera
Cytogenetic Map20p12NCBI
U2af1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540738,895,711 - 38,909,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540738,895,741 - 38,909,820 (+)NCBIChiLan1.0ChiLan1.0
U2AF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22239,148,192 - 39,162,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12134,001,084 - 34,015,646 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02129,399,601 - 29,414,156 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12142,707,738 - 42,719,086 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2142,707,738 - 42,719,086 (-)Ensemblpanpan1.1panPan2
U2AF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13137,263,265 - 37,276,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3136,412,908 - 36,426,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03136,805,348 - 36,818,994 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3136,805,359 - 36,818,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13136,672,392 - 36,686,045 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03136,651,910 - 36,665,348 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,149,648 - 37,163,284 (-)NCBIUU_Cfam_GSD_1.0
U2af1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497136,500,032 - 36,511,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500958,256 - 967,829 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936500937,537 - 967,791 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
U2AF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13206,244,773 - 206,257,702 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113206,244,772 - 206,257,697 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103219520
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1286,949,910 - 86,964,655 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl286,950,056 - 86,964,579 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605414,950,099 - 14,964,875 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
U2af1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474527,647,597 - 27,660,809 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474527,647,672 - 27,660,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in U2af1
386 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:53
Interacting mature miRNAs:60
Transcripts:ENSMUST00000014684, ENSMUST00000166526
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171683545533819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172971116434754437Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse

Markers in Region
U2af1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
cM Map17 UniSTS
RH80644  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38799,945,676 - 99,945,839UniSTSGRCm38
MGSCv377107,094,186 - 107,094,349UniSTSGRCm37
Celera7100,272,487 - 100,272,650UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7E1UniSTS
UniSTS:493126  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38173,043,906 - 3,044,753UniSTSGRCm38
GRCm38799,945,042 - 99,945,837UniSTSGRCm38
MGSCv37173,043,906 - 3,044,753UniSTSGRCm37
MGSCv377107,093,552 - 107,094,347UniSTSGRCm37
Celera7100,271,853 - 100,272,648UniSTS
Celera173,583,198 - 3,584,046UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7E1UniSTS
U2af1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC090881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV453783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000014684   ⟹   ENSMUSP00000014684
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,055 - 31,877,866 (-)Ensembl
GRCm38.p6 Ensembl1731,647,081 - 31,658,892 (-)Ensembl
RefSeq Acc Id: ENSMUST00000166526   ⟹   ENSMUSP00000129864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,055 - 31,877,743 (-)Ensembl
GRCm38.p6 Ensembl1731,647,081 - 31,658,769 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235600
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,871,176 - 31,877,712 (-)Ensembl
GRCm38.p6 Ensembl1731,652,202 - 31,658,738 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235969
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,873,389 - 31,877,677 (-)Ensembl
GRCm38.p6 Ensembl1731,654,415 - 31,658,703 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236260
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,867,286 - 31,875,464 (-)Ensembl
GRCm38.p6 Ensembl1731,648,312 - 31,656,490 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236293
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,263 - 31,868,286 (-)Ensembl
GRCm38.p6 Ensembl1731,647,289 - 31,649,312 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236475   ⟹   ENSMUSP00000157485
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,263 - 31,877,715 (-)Ensembl
GRCm38.p6 Ensembl1731,647,289 - 31,658,741 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237323   ⟹   ENSMUSP00000157853
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,056 - 31,877,729 (-)Ensembl
GRCm38.p6 Ensembl1731,647,082 - 31,658,755 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238046   ⟹   ENSMUSP00000157991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1731,866,224 - 31,877,738 (-)Ensembl
GRCm38.p6 Ensembl1731,647,250 - 31,658,764 (-)Ensembl
RefSeq Acc Id: NM_001163769   ⟹   NP_001157241
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391731,866,056 - 31,877,728 (-)NCBI
GRCm381731,647,082 - 31,658,754 (-)NCBI
MGSCv371731,784,027 - 31,795,699 (-)RGD
Celera1732,564,314 - 32,575,985 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357907   ⟹   NP_001344836
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391731,866,055 - 31,877,738 (-)NCBI
GRCm381731,647,081 - 31,658,764 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024187   ⟹   NP_077149
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391731,866,056 - 31,877,728 (-)NCBI
GRCm381731,647,082 - 31,658,754 (-)NCBI
MGSCv371731,784,027 - 31,795,699 (-)RGD
Celera1732,564,314 - 32,575,985 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523472   ⟹   XP_006523535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391731,866,055 - 31,877,815 (-)NCBI
GRCm381731,647,081 - 31,658,767 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249444   ⟹   XP_030105304
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391731,866,055 - 31,878,122 (-)NCBI
GRCm381731,647,081 - 31,659,148 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_077149   ⟸   NM_024187
- Peptide Label: isoform 1
- UniProtKB: Q99LX2 (UniProtKB/Swiss-Prot),   Q564E4 (UniProtKB/Swiss-Prot),   Q9CZ98 (UniProtKB/Swiss-Prot),   Q9D883 (UniProtKB/Swiss-Prot),   Q14C24 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157241   ⟸   NM_001163769
- Peptide Label: isoform 2
- UniProtKB: G3UW94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523535   ⟸   XM_006523472
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030105304   ⟸   XM_030249444
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001344836   ⟸   NM_001357907
- Peptide Label: isoform 3
RefSeq Acc Id: ENSMUSP00000157853   ⟸   ENSMUST00000237323
RefSeq Acc Id: ENSMUSP00000157485   ⟸   ENSMUST00000236475
RefSeq Acc Id: ENSMUSP00000129864   ⟸   ENSMUST00000166526
RefSeq Acc Id: ENSMUSP00000014684   ⟸   ENSMUST00000014684
RefSeq Acc Id: ENSMUSP00000157991   ⟸   ENSMUST00000238046
Protein Domains
C3H1-type   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D883-F1-model_v2 AlphaFold Q9D883 1-239 view protein structure

Promoters
RGD ID:13675484
Promoter ID:EPDNEW_M21891
Type:initiation region
Name:U2af1_1
Description:Mus musculus U2 small nuclear ribonucleoprotein auxiliary factor1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381731,658,713 - 31,658,773EPDNEW
RGD ID:6828851
Promoter ID:MM_KWN:23016
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001163769,   NM_024187
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361731,795,574 - 31,796,074 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98884 AgrOrtholog
Ensembl Genes ENSMUSG00000061613 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000014684 ENTREZGENE
  ENSMUST00000014684.6 UniProtKB/Swiss-Prot
  ENSMUST00000166526 ENTREZGENE
  ENSMUST00000166526.9 UniProtKB/TrEMBL
  ENSMUST00000236475.2 UniProtKB/TrEMBL
  ENSMUST00000237323.2 UniProtKB/TrEMBL
  ENSMUST00000238046.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  U2AF_small UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
KEGG Report mmu:108121 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98884 ENTREZGENE
NCBI Gene 108121 ENTREZGENE
PANTHER PTHR12620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPLICING FACTOR U2AF 35 KDA SUBUNIT-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen U2af1 PhenoGen
PRINTS U2AUXFACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A494B947_MOUSE UniProtKB/TrEMBL
  A0A494B9X9_MOUSE UniProtKB/TrEMBL
  A0A494BA95_MOUSE UniProtKB/TrEMBL
  G3UW94 ENTREZGENE, UniProtKB/TrEMBL
  Q14C24 ENTREZGENE, UniProtKB/TrEMBL
  Q564E4 ENTREZGENE
  Q99LX2 ENTREZGENE
  Q9CZ98 ENTREZGENE
  Q9D883 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q564E4 UniProtKB/Swiss-Prot
  Q99LX2 UniProtKB/Swiss-Prot
  Q9CZ98 UniProtKB/Swiss-Prot