CAPN2 (calpain 2) - Rat Genome Database

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Gene: CAPN2 (calpain 2) Homo sapiens
Analyze
Symbol: CAPN2
Name: calpain 2
RGD ID: 732800
HGNC Page HGNC:1479
Description: Enables calcium-dependent cysteine-type endopeptidase activity. Involved in proteolysis involved in protein catabolic process. Located in several cellular components, including calpain complex; perinuclear endoplasmic reticulum; and pseudopodium. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: calcium-activated neutral proteinase 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain large polypeptide L2; calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; calpain-2 large subunit; CANP 2; CANP2; CANPL2; CANPml; FLJ39928; M-calpain; mCANP; millimolar-calpain
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Candidate Gene For: BW86_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381223,701,597 - 223,776,018 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1223,701,593 - 223,776,018 (+)EnsemblGRCh38hg38GRCh38
GRCh371223,889,299 - 223,963,720 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,966,742 - 222,030,343 (+)NCBINCBI36Build 36hg18NCBI36
Build 341220,206,935 - 220,270,453NCBI
Celera1197,044,917 - 197,119,643 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1194,501,759 - 194,576,134 (+)NCBIHuRef
CHM1_11225,161,051 - 225,236,057 (+)NCBICHM1_1
T2T-CHM13v2.01222,891,307 - 222,965,751 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-tribromophenol  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-aminophenol  (ISO)
4-hydroxynon-2-enal  (EXP)
4-phenylbutyric acid  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6alpha-methylprednisolone  (ISO)
8-Br-cAMP  (EXP)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acetylsalicylic acid  (EXP)
acrolein  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
agomelatine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
Ammothamnine  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP)
atrazine  (ISO)
BAPTA  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
bucladesine  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
caffeine  (EXP)
calcitriol  (EXP)
Calpeptin  (ISO)
cannabidiol  (EXP)
cantharidin  (EXP)
carbamazepine  (EXP)
carbon disulfide  (ISO)
carbon nanotube  (ISO)
casticin  (EXP)
chlordecone  (ISO)
chloroacetic acid  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
dantrolene  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dibenzo[a,l]pyrene  (EXP)
dicrotophos  (EXP)
diethylstilbestrol  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fipronil  (ISO)
fisetin  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
geneticin  (EXP)
gentamycin  (ISO)
glimepiride  (EXP)
glyburide  (EXP)
heparin  (ISO)
Honokiol  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
indometacin  (EXP,ISO)
isoflurane  (ISO)
isoprenaline  (ISO)
ivermectin  (EXP)
lipopolysaccharide  (EXP,ISO)
medroxyprogesterone acetate  (EXP)
menadione  (EXP)
methapyrilene  (EXP)
methimazole  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (EXP)
microcystin-LR  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-D-aspartic acid  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (EXP)
nimesulide  (ISO)
nitroglycerin  (ISO)
NS-398  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
paraquat  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procaine  (ISO)
propiconazole  (ISO)
quercetin  (EXP,ISO)
raloxifene  (EXP)
SB 431542  (EXP)
sodium arsenite  (EXP,ISO)
surfactin  (EXP)
surfactin C  (EXP)
tamoxifen  (EXP)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP,ISO)
testosterone enanthate  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
tungsten  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vildagliptin  (ISO)
vorinostat  (EXP)
Z-Val-Phe-H  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Knockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity. Bevers MB, etal., J Neurochem. 2009 Mar;108(5):1237-50. doi: 10.1111/j.1471-4159.2008.05860.x. Epub 2009 Jan 22.
2. Calpain/calpastatin activities and substrate depletion patterns during hindlimb unweighting and reweighting in skeletal muscle. Enns DL, etal., Eur J Appl Physiol. 2007 Jul;100(4):445-55. Epub 2007 Apr 12.
3. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
4. Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles. Matsumoto A, etal., Acta Histochem. 2014 Jun;116(5):936-42. doi: 10.1016/j.acthis.2014.03.006. Epub 2014 Apr 16.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Nuclear Translocation of Calpain-2 Mediates Apoptosis of Hypertrophied Cardiomyocytes in Transverse Aortic Constriction Rat. Sheng JJ, etal., J Cell Physiol. 2015 Nov;230(11):2743-54. doi: 10.1002/jcp.24999.
9. m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains. Tsuji T, etal., Neurosci Lett. 1998 May 29;248(2):109-12.
10. Calpain-2 contributes to neuropathic pain following motor nerve injury via up-regulating interleukin-6 in DRG neurons. Zang Y, etal., Brain Behav Immun. 2015 Feb;44:37-47. doi: 10.1016/j.bbi.2014.08.003. Epub 2014 Aug 20.
11. Cardiac protective effects of dexrazoxane on animal cardiotoxicity model induced by anthracycline combined with trastuzumab is associated with upregulation of calpain-2. Zhang S, etal., Medicine (Baltimore). 2015 Jan;94(4):e445. doi: 10.1097/MD.0000000000000445.
12. Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: a casein zymography study. Zhao X, etal., J Cereb Blood Flow Metab. 1998 Feb;18(2):161-7. doi: 10.1097/00004647-199802000-00006.
Additional References at PubMed
PMID:1067155   PMID:1527057   PMID:2209092   PMID:2539381   PMID:2852952   PMID:3038169   PMID:8561910   PMID:8900201   PMID:8954122   PMID:9213221   PMID:9337844   PMID:9407132  
PMID:9562261   PMID:9873017   PMID:10639123   PMID:10666632   PMID:10671558   PMID:10830966   PMID:10944468   PMID:10978167   PMID:11023826   PMID:11387205   PMID:11483505   PMID:11517928  
PMID:11673052   PMID:11853546   PMID:12000759   PMID:12070670   PMID:12130691   PMID:12150984   PMID:12477932   PMID:12665801   PMID:12783889   PMID:14559243   PMID:14688278   PMID:14702039  
PMID:14976200   PMID:14980313   PMID:14993287   PMID:15302874   PMID:15471877   PMID:15489334   PMID:15590481   PMID:15817486   PMID:15950654   PMID:16310784   PMID:16344560   PMID:16361262  
PMID:16436382   PMID:16530191   PMID:16598790   PMID:16652152   PMID:16816119   PMID:16998475   PMID:17192410   PMID:17261541   PMID:17359359   PMID:17596297   PMID:17643375   PMID:17650508  
PMID:17897354   PMID:18032503   PMID:18239623   PMID:18332219   PMID:18340456   PMID:18519038   PMID:18568448   PMID:19056867   PMID:19074885   PMID:19199708   PMID:19422794   PMID:19720936  
PMID:19752040   PMID:19756344   PMID:19861418   PMID:19913121   PMID:19946123   PMID:20041182   PMID:20070945   PMID:20150423   PMID:20193680   PMID:20379614   PMID:20453000   PMID:20618160  
PMID:20628086   PMID:20729206   PMID:20730561   PMID:20890123   PMID:20924799   PMID:20962236   PMID:21086148   PMID:21117903   PMID:21152086   PMID:21185840   PMID:21374734   PMID:21423176  
PMID:21839844   PMID:21873635   PMID:22064597   PMID:22199357   PMID:22335024   PMID:22435971   PMID:22623320   PMID:22629380   PMID:22711986   PMID:22745213   PMID:22863883   PMID:22990118  
PMID:23140395   PMID:23376485   PMID:23389291   PMID:23395904   PMID:23466492   PMID:23538341   PMID:23667531   PMID:23733271   PMID:23889979   PMID:23940116   PMID:24705354   PMID:24778252  
PMID:25344690   PMID:25486428   PMID:25659891   PMID:25921289   PMID:25944670   PMID:26124079   PMID:26186194   PMID:26248159   PMID:26344197   PMID:26358320   PMID:26496610   PMID:26618866  
PMID:26816005   PMID:26972000   PMID:26974350   PMID:27077802   PMID:27099352   PMID:27121057   PMID:27123462   PMID:27277673   PMID:27432908   PMID:27456359   PMID:27731380   PMID:28002826  
PMID:28112201   PMID:28235949   PMID:28280729   PMID:28319173   PMID:28334907   PMID:28514442   PMID:28515276   PMID:28675297   PMID:28973437   PMID:29099266   PMID:29115452   PMID:29425806  
PMID:29467282   PMID:29507755   PMID:29511337   PMID:29909039   PMID:29987050   PMID:30106446   PMID:30177525   PMID:30177812   PMID:30417356   PMID:30448882   PMID:30711629   PMID:30979931  
PMID:31024071   PMID:31073040   PMID:31324722   PMID:31470122   PMID:31540324   PMID:31617661   PMID:31634637   PMID:31680308   PMID:31911079   PMID:31950832   PMID:31980649   PMID:32416067  
PMID:32687490   PMID:32814053   PMID:33078830   PMID:33853758   PMID:33961781   PMID:34191270   PMID:34381117   PMID:34857952   PMID:35013556   PMID:35063084   PMID:35241646   PMID:35256949  
PMID:35509820   PMID:35831314   PMID:36114006   PMID:36215168   PMID:36282215   PMID:37663545   PMID:37827155   PMID:38113892  


Genomics

Comparative Map Data
CAPN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381223,701,597 - 223,776,018 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1223,701,593 - 223,776,018 (+)EnsemblGRCh38hg38GRCh38
GRCh371223,889,299 - 223,963,720 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,966,742 - 222,030,343 (+)NCBINCBI36Build 36hg18NCBI36
Build 341220,206,935 - 220,270,453NCBI
Celera1197,044,917 - 197,119,643 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1194,501,759 - 194,576,134 (+)NCBIHuRef
CHM1_11225,161,051 - 225,236,057 (+)NCBICHM1_1
T2T-CHM13v2.01222,891,307 - 222,965,751 (+)NCBIT2T-CHM13v2.0
Capn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,294,818 - 182,345,175 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1182,294,825 - 182,345,173 (-)EnsemblGRCm39 Ensembl
GRCm381182,467,253 - 182,517,610 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,467,260 - 182,517,608 (-)EnsemblGRCm38mm10GRCm38
MGSCv371184,397,390 - 184,447,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361184,303,935 - 184,354,199 (-)NCBIMGSCv36mm8
Celera1189,509,702 - 189,560,154 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map184.93NCBI
Capn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81396,681,902 - 96,732,625 (-)NCBIGRCr8
mRatBN7.21394,150,244 - 94,200,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1394,150,240 - 94,200,969 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1396,655,495 - 96,706,202 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01398,055,407 - 98,106,133 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01395,237,587 - 95,288,310 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013100,878,649 - 100,928,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13100,878,650 - 100,928,811 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013105,814,749 - 105,864,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41398,473,367 - 98,524,463 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11398,662,303 - 98,713,399 (-)NCBI
Celera1393,683,410 - 93,734,060 (-)NCBICelera
Cytogenetic Map13q26NCBI
Capn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555201,286,356 - 1,315,328 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555201,287,829 - 1,315,318 (-)NCBIChiLan1.0ChiLan1.0
CAPN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2125,592,267 - 25,655,726 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1125,548,169 - 25,611,611 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01199,335,582 - 199,399,267 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11204,346,476 - 204,410,137 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1204,335,573 - 204,409,150 (+)Ensemblpanpan1.1panPan2
CAPN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1740,333,379 - 40,367,158 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl740,334,012 - 40,377,037 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha739,815,620 - 39,853,714 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0740,166,074 - 40,204,194 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl740,166,086 - 40,204,215 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1740,007,852 - 40,045,930 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0740,016,382 - 40,054,477 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0740,285,433 - 40,323,542 (-)NCBIUU_Cfam_GSD_1.0
Capn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934453,814,785 - 53,867,532 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936526879,765 - 932,682 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936526879,765 - 932,682 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1019,758,757 - 19,820,246 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11019,758,824 - 19,820,241 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CAPN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,845,873 - 5,905,464 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl255,846,298 - 5,905,402 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660556,059,645 - 6,119,546 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CAPN2
55 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q32.3-44(chr1:214023812-248918469)x3 copy number gain See cases [RCV000050981] Chr1:214023812..248918469 [GRCh38]
Chr1:214197155..249212668 [GRCh37]
Chr1:212263778..247179291 [NCBI36]
Chr1:1q32.3-44
pathogenic
GRCh38/hg38 1q41-44(chr1:223347693-248918469)x3 copy number gain See cases [RCV000050581] Chr1:223347693..248918469 [GRCh38]
Chr1:223521035..249212668 [GRCh37]
Chr1:221587658..247179291 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q41-44(chr1:221902539-248918469)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051875]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051875]|See cases [RCV000051875] Chr1:221902539..248918469 [GRCh38]
Chr1:222075881..249212668 [GRCh37]
Chr1:220142504..247179291 [NCBI36]
Chr1:1q41-44
pathogenic
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11
pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh38/hg38 1q41-42.13(chr1:221519280-228862141)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053955]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053955]|See cases [RCV000053955] Chr1:221519280..228862141 [GRCh38]
Chr1:221692622..228997888 [GRCh37]
Chr1:219759245..227064511 [NCBI36]
Chr1:1q41-42.13
pathogenic
NM_001146068.1(CAPN2):c.1148G>A (p.Arg383His) single nucleotide variant Malignant melanoma [RCV000060095] Chr1:223759334 [GRCh38]
Chr1:223947036 [GRCh37]
Chr1:222013659 [NCBI36]
Chr1:1q41
not provided
NM_001146068.1(CAPN2):c.1237C>T (p.Pro413Ser) single nucleotide variant Malignant melanoma [RCV000064549] Chr1:223759423 [GRCh38]
Chr1:223947125 [GRCh37]
Chr1:222013748 [NCBI36]
Chr1:1q41
not provided
NM_001146068.1(CAPN2):c.73+11966G>A single nucleotide variant Lung cancer [RCV000090556] Chr1:223729797 [GRCh38]
Chr1:223917499 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.848G>C (p.Arg283Pro) single nucleotide variant Inborn genetic diseases [RCV003203546] Chr1:223750924 [GRCh38]
Chr1:223938626 [GRCh37]
Chr1:1q41
uncertain significance
GRCh38/hg38 1q41-42.12(chr1:223749425-224604271)x1 copy number loss See cases [RCV000135362] Chr1:223749425..224604271 [GRCh38]
Chr1:223937127..224791973 [GRCh37]
Chr1:222003750..222858596 [NCBI36]
Chr1:1q41-42.12
uncertain significance
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh38/hg38 1q41(chr1:222676842-223882311)x1 copy number loss See cases [RCV000135634] Chr1:222676842..223882311 [GRCh38]
Chr1:222850184..224070013 [GRCh37]
Chr1:220916807..222136636 [NCBI36]
Chr1:1q41
likely pathogenic|likely benign
GRCh38/hg38 1q41-42.13(chr1:223347693-228556332)x1 copy number loss See cases [RCV000136636] Chr1:223347693..228556332 [GRCh38]
Chr1:223521035..228744033 [GRCh37]
Chr1:221587658..226810656 [NCBI36]
Chr1:1q41-42.13
pathogenic
GRCh38/hg38 1q41(chr1:223742902-223749425)x3 copy number gain See cases [RCV000140163] Chr1:223742902..223749425 [GRCh38]
Chr1:223930604..223937127 [GRCh37]
Chr1:221997227..222003750 [NCBI36]
Chr1:1q41
likely benign
GRCh38/hg38 1q32.1-42.12(chr1:204764914-225408698)x3 copy number gain See cases [RCV000142054] Chr1:204764914..225408698 [GRCh38]
Chr1:204734042..225596400 [GRCh37]
Chr1:203000665..223663023 [NCBI36]
Chr1:1q32.1-42.12
pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44
pathogenic
GRCh37/hg19 1q31.3-42.13(chr1:197811907-228997888)x3 copy number gain See cases [RCV000240137] Chr1:197811907..228997888 [GRCh37]
Chr1:1q31.3-42.13
pathogenic
NM_001748.5(CAPN2):c.63C>A (p.His21Gln) single nucleotide variant Inborn genetic diseases [RCV003204642] Chr1:223712703 [GRCh38]
Chr1:223900405 [GRCh37]
Chr1:1q41
uncertain significance
GRCh37/hg19 1q31.3-44(chr1:195483439-249213000)x3 copy number gain See cases [RCV000449172] Chr1:195483439..249213000 [GRCh37]
Chr1:1q31.3-44
pathogenic
GRCh37/hg19 1q41-44(chr1:214697099-249224684)x3 copy number gain See cases [RCV000449210] Chr1:214697099..249224684 [GRCh37]
Chr1:1q41-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
NM_001748.5(CAPN2):c.1274A>T (p.Asp425Val) single nucleotide variant Inborn genetic diseases [RCV003243926] Chr1:223755618 [GRCh38]
Chr1:223943320 [GRCh37]
Chr1:1q41
uncertain significance
GRCh37/hg19 1q41-44(chr1:218252551-249224684)x3 copy number gain not provided [RCV000684700] Chr1:218252551..249224684 [GRCh37]
Chr1:1q41-44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q41-42.2(chr1:223653722-234591807)x1 copy number loss not provided [RCV001005180] Chr1:223653722..234591807 [GRCh37]
Chr1:1q41-42.2
pathogenic
NM_001748.5(CAPN2):c.2067C>T (p.Leu689=) single nucleotide variant not provided [RCV000936680] Chr1:223772227 [GRCh38]
Chr1:223959929 [GRCh37]
Chr1:1q41
likely benign
NM_001748.5(CAPN2):c.550G>A (p.Ala184Thr) single nucleotide variant not provided [RCV000892261] Chr1:223745429 [GRCh38]
Chr1:223933131 [GRCh37]
Chr1:1q41
likely benign
NM_001748.5(CAPN2):c.2029A>C (p.Lys677Gln) single nucleotide variant not provided [RCV000964492] Chr1:223772189 [GRCh38]
Chr1:223959891 [GRCh37]
Chr1:1q41
benign
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3 copy number gain not provided [RCV000845852] Chr1:182388773..249111240 [GRCh37]
Chr1:1q25.3-44
pathogenic
NM_001748.5(CAPN2):c.1406G>A (p.Arg469Gln) single nucleotide variant Inborn genetic diseases [RCV003244611] Chr1:223759358 [GRCh38]
Chr1:223947060 [GRCh37]
Chr1:1q41
uncertain significance
GRCh37/hg19 1q41-43(chr1:219916966-239004378)x3 copy number gain not provided [RCV001005175] Chr1:219916966..239004378 [GRCh37]
Chr1:1q41-43
pathogenic
NM_001748.5(CAPN2):c.2015T>C (p.Leu672Pro) single nucleotide variant Inborn genetic diseases [RCV003264694] Chr1:223771920 [GRCh38]
Chr1:223959622 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.144C>T (p.Asp48=) single nucleotide variant not provided [RCV000888446] Chr1:223712784 [GRCh38]
Chr1:223900486 [GRCh37]
Chr1:1q41
benign
NM_001748.5(CAPN2):c.235_237+11dup duplication not provided [RCV000973663] Chr1:223712873..223712874 [GRCh38]
Chr1:223900575..223900576 [GRCh37]
Chr1:1q41
benign
NM_001748.5(CAPN2):c.1044C>T (p.Leu348=) single nucleotide variant not provided [RCV000889883] Chr1:223752865 [GRCh38]
Chr1:223940567 [GRCh37]
Chr1:1q41
benign
GRCh37/hg19 1q41-42.13(chr1:222641389-228137574)x1 copy number loss not provided [RCV001005178] Chr1:222641389..228137574 [GRCh37]
Chr1:1q41-42.13
pathogenic
GRCh37/hg19 1q32.2-44(chr1:210152794-249218992)x3 copy number gain See cases [RCV001194578] Chr1:210152794..249218992 [GRCh37]
Chr1:1q32.2-44
pathogenic
GRCh37/hg19 1q32.1-44(chr1:204045948-249218992)x3 copy number gain See cases [RCV001007407] Chr1:204045948..249218992 [GRCh37]
Chr1:1q32.1-44
pathogenic
GRCh37/hg19 1q41-42.11(chr1:219734913-224104993)x1 copy number loss not provided [RCV001005174] Chr1:219734913..224104993 [GRCh37]
Chr1:1q41-42.11
pathogenic
GRCh37/hg19 1q41-42.12(chr1:222605125-224696628)x1 copy number loss not provided [RCV001259110] Chr1:222605125..224696628 [GRCh37]
Chr1:1q41-42.12
pathogenic
GRCh37/hg19 1q41-42.12(chr1:223552998-224761890) copy number loss Global developmental delay [RCV001291986] Chr1:223552998..224761890 [GRCh37]
Chr1:1q41-42.12
pathogenic
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44
uncertain significance
GRCh37/hg19 1q41-42.13(chr1:221303919-227461343) copy number gain not specified [RCV002052845] Chr1:221303919..227461343 [GRCh37]
Chr1:1q41-42.13
pathogenic
NM_001748.5(CAPN2):c.266T>C (p.Ile89Thr) single nucleotide variant Inborn genetic diseases [RCV003280670] Chr1:223717790 [GRCh38]
Chr1:223905492 [GRCh37]
Chr1:1q41
uncertain significance
GRCh37/hg19 1q31.3-44(chr1:197867914-249224684)x3 copy number gain See cases [RCV002287837] Chr1:197867914..249224684 [GRCh37]
Chr1:1q31.3-44
pathogenic
GRCh37/hg19 1q41-42.12(chr1:221325488-225804228)x1 copy number loss not provided [RCV002474859] Chr1:221325488..225804228 [GRCh37]
Chr1:1q41-42.12
uncertain significance
NM_001748.5(CAPN2):c.1913T>C (p.Met638Thr) single nucleotide variant Inborn genetic diseases [RCV002773328] Chr1:223771818 [GRCh38]
Chr1:223959520 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1328A>G (p.Gln443Arg) single nucleotide variant Inborn genetic diseases [RCV002840927] Chr1:223759280 [GRCh38]
Chr1:223946982 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1739T>C (p.Met580Thr) single nucleotide variant Inborn genetic diseases [RCV002816785] Chr1:223766415 [GRCh38]
Chr1:223954117 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.215G>A (p.Gly72Asp) single nucleotide variant Inborn genetic diseases [RCV002753365] Chr1:223712855 [GRCh38]
Chr1:223900557 [GRCh37]
Chr1:1q41
uncertain significance
GRCh38/hg38 1q32.2-42.13(chr1:228006998-228061271)x2 copy number loss Orofacial cleft 2 [RCV002481175] Chr1:228006998..228061271 [GRCh38]
Chr1:1q32.2-42.13
association
NM_001748.5(CAPN2):c.1589T>C (p.Ile530Thr) single nucleotide variant Inborn genetic diseases [RCV002694557] Chr1:223762208 [GRCh38]
Chr1:223949910 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.897C>A (p.Asp299Glu) single nucleotide variant Inborn genetic diseases [RCV002912036] Chr1:223750973 [GRCh38]
Chr1:223938675 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1192G>A (p.Glu398Lys) single nucleotide variant Inborn genetic diseases [RCV002977135] Chr1:223755536 [GRCh38]
Chr1:223943238 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.38A>C (p.Glu13Ala) single nucleotide variant Inborn genetic diseases [RCV002823091] Chr1:223712678 [GRCh38]
Chr1:223900380 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1001A>T (p.His334Leu) single nucleotide variant Inborn genetic diseases [RCV002744194] Chr1:223752822 [GRCh38]
Chr1:223940524 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.2074A>G (p.Ile692Val) single nucleotide variant Inborn genetic diseases [RCV002768318] Chr1:223772234 [GRCh38]
Chr1:223959936 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1724A>T (p.Glu575Val) single nucleotide variant Inborn genetic diseases [RCV002916817] Chr1:223766400 [GRCh38]
Chr1:223954102 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1940T>C (p.Val647Ala) single nucleotide variant Inborn genetic diseases [RCV002986894] Chr1:223771845 [GRCh38]
Chr1:223959547 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.400A>G (p.Asn134Asp) single nucleotide variant Inborn genetic diseases [RCV002742668] Chr1:223744192 [GRCh38]
Chr1:223931894 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1898A>C (p.Glu633Ala) single nucleotide variant Inborn genetic diseases [RCV002641735] Chr1:223770520 [GRCh38]
Chr1:223958222 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1353C>G (p.Asn451Lys) single nucleotide variant Inborn genetic diseases [RCV002961310] Chr1:223759305 [GRCh38]
Chr1:223947007 [GRCh37]
Chr1:1q41
likely benign
NM_001748.5(CAPN2):c.1846G>A (p.Val616Ile) single nucleotide variant Inborn genetic diseases [RCV002813437] Chr1:223770468 [GRCh38]
Chr1:223958170 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.2039A>G (p.Asp680Gly) single nucleotide variant Inborn genetic diseases [RCV002668831] Chr1:223772199 [GRCh38]
Chr1:223959901 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1991G>A (p.Arg664Gln) single nucleotide variant Inborn genetic diseases [RCV002702785] Chr1:223771896 [GRCh38]
Chr1:223959598 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.193C>A (p.Pro65Thr) single nucleotide variant Inborn genetic diseases [RCV002718421] Chr1:223712833 [GRCh38]
Chr1:223900535 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1420C>T (p.Arg474Cys) single nucleotide variant Inborn genetic diseases [RCV002878721] Chr1:223759372 [GRCh38]
Chr1:223947074 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1083G>A (p.Met361Ile) single nucleotide variant Inborn genetic diseases [RCV002792633] Chr1:223752904 [GRCh38]
Chr1:223940606 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.568G>A (p.Gly190Arg) single nucleotide variant Inborn genetic diseases [RCV002703079] Chr1:223747004 [GRCh38]
Chr1:223934706 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1757C>T (p.Ser586Leu) single nucleotide variant Inborn genetic diseases [RCV002724582] Chr1:223769842 [GRCh38]
Chr1:223957544 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.602C>G (p.Thr201Ser) single nucleotide variant Inborn genetic diseases [RCV003190539] Chr1:223747038 [GRCh38]
Chr1:223934740 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.2027T>C (p.Phe676Ser) single nucleotide variant Inborn genetic diseases [RCV003178534] Chr1:223772187 [GRCh38]
Chr1:223959889 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1114G>A (p.Gly372Arg) single nucleotide variant Inborn genetic diseases [RCV003212176] Chr1:223752935 [GRCh38]
Chr1:223940637 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.83T>C (p.Leu28Pro) single nucleotide variant Inborn genetic diseases [RCV003216218] Chr1:223712723 [GRCh38]
Chr1:223900425 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.850A>G (p.Ile284Val) single nucleotide variant Inborn genetic diseases [RCV003185673] Chr1:223750926 [GRCh38]
Chr1:223938628 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1100G>A (p.Arg367Gln) single nucleotide variant Inborn genetic diseases [RCV003365861] Chr1:223752921 [GRCh38]
Chr1:223940623 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.343A>G (p.Thr115Ala) single nucleotide variant Inborn genetic diseases [RCV003346794] Chr1:223744135 [GRCh38]
Chr1:223931837 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1852A>G (p.Arg618Gly) single nucleotide variant Inborn genetic diseases [RCV003352561] Chr1:223770474 [GRCh38]
Chr1:223958176 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.167C>T (p.Ser56Leu) single nucleotide variant Inborn genetic diseases [RCV003356012] Chr1:223712807 [GRCh38]
Chr1:223900509 [GRCh37]
Chr1:1q41
uncertain significance
GRCh37/hg19 1q41-42.11(chr1:222641390-224104993)x1 copy number loss not provided [RCV003484055] Chr1:222641390..224104993 [GRCh37]
Chr1:1q41-42.11
uncertain significance
NM_001748.5(CAPN2):c.585A>G (p.Leu195=) single nucleotide variant not provided [RCV003414792] Chr1:223747021 [GRCh38]
Chr1:223934723 [GRCh37]
Chr1:1q41
likely benign
GRCh37/hg19 1q41(chr1:222698623-224065782)x3 copy number gain not specified [RCV003986209] Chr1:222698623..224065782 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.1811T>C (p.Ile604Thr) single nucleotide variant Inborn genetic diseases [RCV003383848] Chr1:223769896 [GRCh38]
Chr1:223957598 [GRCh37]
Chr1:1q41
uncertain significance
NM_001748.5(CAPN2):c.35G>C (p.Arg12Pro) single nucleotide variant Inborn genetic diseases [RCV003378699] Chr1:223712675 [GRCh38]
Chr1:223900377 [GRCh37]
Chr1:1q41
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2593
Count of miRNA genes:932
Interacting mature miRNAs:1096
Transcripts:ENST00000295006, ENST00000433674, ENST00000434648, ENST00000463997, ENST00000472601, ENST00000474026, ENST00000480581, ENST00000483579, ENST00000487223, ENST00000492565, ENST00000492664, ENST00000498027
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D1S3584  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371223,963,253 - 223,963,354UniSTSGRCh37
Build 361222,029,876 - 222,029,977RGDNCBI36
Celera1197,119,176 - 197,119,277RGD
Cytogenetic Map1q41-q42UniSTS
HuRef1194,575,667 - 194,575,768UniSTS
TNG Radiation Hybrid Map1110676.0UniSTS
TNG Radiation Hybrid Map1110685.0UniSTS
GeneMap99-GB4 RH Map1711.73UniSTS
GeneMap99-G3 RH Map18785.0UniSTS
AL009595  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371223,908,851 - 223,909,013UniSTSGRCh37
Build 361221,975,474 - 221,975,636RGDNCBI36
Celera1197,064,768 - 197,064,930RGD
Cytogenetic Map1q41-q42UniSTS
HuRef1194,521,314 - 194,521,476UniSTS
D1S2550  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371223,951,682 - 223,951,890UniSTSGRCh37
Build 361222,018,305 - 222,018,513RGDNCBI36
Celera1197,107,609 - 197,107,817RGD
Cytogenetic Map1q41-q42UniSTS
HuRef1194,564,096 - 194,564,304UniSTS
Stanford-G3 RH Map18710.0UniSTS
NCBI RH Map11899.1UniSTS
SHGC-76403  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371223,963,256 - 223,963,407UniSTSGRCh37
Build 361222,029,879 - 222,030,030RGDNCBI36
Celera1197,119,179 - 197,119,330RGD
Cytogenetic Map1q41-q42UniSTS
HuRef1194,575,670 - 194,575,821UniSTS
TNG Radiation Hybrid Map1110676.0UniSTS
GeneMap99-GB4 RH Map1712.68UniSTS
UniSTS:56629  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371223,962,637 - 223,962,975UniSTSGRCh37
Build 361222,029,260 - 222,029,598RGDNCBI36
Celera1197,118,560 - 197,118,898RGD
HuRef1194,575,051 - 194,575,389UniSTS
D1S1423  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map10p12.1-p11.2UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map6p22.3-p21.32UniSTS
Cytogenetic Map6q22.33UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map7q11.2UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map9q12UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map18q22.1UniSTS
Cytogenetic Map13q12UniSTS
Cytogenetic Map10p14-p13UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map11q23-q24UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map22cen-q12.3UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map15q11.2-q21.3UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map10p15.1UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map4q28UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map1q41-q42UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map12p13.1-p12.3UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map1p13.1UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map4q23UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map10q26.11UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map11q24.1UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map2q24.3UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map18p11.31-p11.21UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map3q13UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map7p21.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map1q42.1UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map1p34-p33UniSTS
Cytogenetic Map3q22.1UniSTS
Cytogenetic Map7p14UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map12q24.2UniSTS
Cytogenetic Map20q13UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map8p23-p22UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map10p12.33UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map3q26UniSTS
Cytogenetic Map9p21.2UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map5q21.3UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map3q26.31UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map10q22.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map20p12.3-p11.21UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic MapXq27.2UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map4q31UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map10q24.3UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map11q22.1UniSTS
Cytogenetic Map12q14.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map20q11.21-q11.23UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map21p11.1UniSTS
Cytogenetic Map1p35-p34.3UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map14q32.1UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map4q31.23UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map2p22.3UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map15q15.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map13q33.3UniSTS
Cytogenetic Map15q22-q24UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map20q13.1UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map15q22.1-q22.31UniSTS
Cytogenetic Map1q31-q41UniSTS
Cytogenetic Map6q23.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map14q23UniSTS
Cytogenetic Map12q11-q12UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map1p32UniSTS
Cytogenetic Map3p21.1-p14.2UniSTS
Cytogenetic Map12q22-q23.1UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map6q24.2UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map3p22.3UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic MapXq13-q21UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map10pter-q25.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic Map3q28-q29UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map6p22.2UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map22q11UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map16p13.11UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map9p21UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map11q13.1-q13.3UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map15q26UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map4p15.1-p14UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic MapXp22.12UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map5q33.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map7q32.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map15q25.1UniSTS
Cytogenetic Map9p13UniSTS
Cytogenetic Map2p24.2UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map3q21-q24UniSTS
Cytogenetic Map4q13UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map4q34.3UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map13q13.3UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map1q31UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map8q24.12UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map13q11-q12UniSTS
Cytogenetic Map10q24.2UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map6q25.2UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map6q14.1UniSTS
Cytogenetic Map3q23-q24UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map20pter-p12UniSTS
Cytogenetic MapXp22.11UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map7q31.3UniSTS
Cytogenetic Map21q22.13UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map18p11.22UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map14q22.2UniSTS
Cytogenetic Map20p11.22-p11.1UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map2q12.2UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map11q12-q13UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map6p22-p21UniSTS
Cytogenetic Map17q21.1-q21.3UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map12p13.2-p12.3UniSTS
Cytogenetic Map9q22.32UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map5q22.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map4p15.3UniSTS
Cytogenetic Map4q28.1UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map9p22.3UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map8q21.11UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map6q22.32UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map18q12.2UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map13q33.1UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map5q12.1UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map10q22.3-q23.2UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map4q21.3UniSTS
Cytogenetic Map7p13-p12UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map3q12.1UniSTS
Cytogenetic Map7q21.1-q22UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map3q26.32UniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map2p13.2UniSTS
Cytogenetic Map3p12.3UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map3q11.2UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map6p24.2UniSTS
Cytogenetic Map20q13.33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1
Medium 2430 2795 1500 404 1537 246 4342 2158 3541 413 1439 1599 171 1204 2786 3
Low 2 189 223 219 352 218 13 35 167 5 10 5 2 1 1
Below cutoff 1 2 42 1 2 5 1 6 3 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001146068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047431344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054338935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002957688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC096542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC099065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF261089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI089162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK056838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY835586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA448245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000295006   ⟹   ENSP00000295006
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,712,539 - 223,776,018 (+)Ensembl
RefSeq Acc Id: ENST00000433674   ⟹   ENSP00000413158
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,701,593 - 223,776,016 (+)Ensembl
RefSeq Acc Id: ENST00000434648   ⟹   ENSP00000399949
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,701,645 - 223,747,063 (+)Ensembl
RefSeq Acc Id: ENST00000463997
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,770,623 - 223,776,018 (+)Ensembl
RefSeq Acc Id: ENST00000472601
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,769,841 - 223,772,710 (+)Ensembl
RefSeq Acc Id: ENST00000474026
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,757,624 - 223,776,018 (+)Ensembl
RefSeq Acc Id: ENST00000480581
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,752,019 - 223,757,497 (+)Ensembl
RefSeq Acc Id: ENST00000483579
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,747,108 - 223,749,476 (+)Ensembl
RefSeq Acc Id: ENST00000487223
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,758,226 - 223,776,018 (+)Ensembl
RefSeq Acc Id: ENST00000492565
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,759,434 - 223,764,207 (+)Ensembl
RefSeq Acc Id: ENST00000492664
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,770,413 - 223,772,710 (+)Ensembl
RefSeq Acc Id: ENST00000498027
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1223,770,315 - 223,773,257 (+)Ensembl
RefSeq Acc Id: NM_001146068   ⟹   NP_001139540
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,701,597 - 223,776,018 (+)NCBI
GRCh371223,889,295 - 223,963,720 (+)ENTREZGENE
HuRef1194,501,759 - 194,576,134 (+)ENTREZGENE
CHM1_11225,161,051 - 225,236,057 (+)NCBI
T2T-CHM13v2.01222,891,307 - 222,965,751 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001748   ⟹   NP_001739
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,712,539 - 223,776,018 (+)NCBI
GRCh371223,889,295 - 223,963,720 (+)ENTREZGENE
Build 361221,966,742 - 222,030,343 (+)NCBI Archive
HuRef1194,501,759 - 194,576,134 (+)ENTREZGENE
CHM1_11225,172,456 - 225,236,057 (+)NCBI
T2T-CHM13v2.01222,902,264 - 222,965,751 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047431344   ⟹   XP_047287300
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,712,539 - 223,758,331 (+)NCBI
RefSeq Acc Id: XM_054338935   ⟹   XP_054194910
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01222,902,264 - 222,948,742 (+)NCBI
RefSeq Acc Id: NP_001139540   ⟸   NM_001146068
- Peptide Label: isoform 2
- UniProtKB: B4DN77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001739   ⟸   NM_001748
- Peptide Label: isoform 1
- UniProtKB: Q8WU26 (UniProtKB/Swiss-Prot),   Q6PJT3 (UniProtKB/Swiss-Prot),   Q16738 (UniProtKB/Swiss-Prot),   P17655 (UniProtKB/Swiss-Prot),   E7ES58 (UniProtKB/Swiss-Prot),   B7ZA96 (UniProtKB/Swiss-Prot),   A6NDG7 (UniProtKB/Swiss-Prot),   Q9HBB1 (UniProtKB/Swiss-Prot),   B2RCM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000295006   ⟸   ENST00000295006
RefSeq Acc Id: ENSP00000413158   ⟸   ENST00000433674
RefSeq Acc Id: ENSP00000399949   ⟸   ENST00000434648
RefSeq Acc Id: XP_047287300   ⟸   XM_047431344
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054194910   ⟸   XM_054338935
- Peptide Label: isoform X1
Protein Domains
Calpain catalytic   EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17655-F1-model_v2 AlphaFold P17655 1-700 view protein structure

Promoters
RGD ID:6784844
Promoter ID:HG_KWN:7494
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000295006,   OTTHUMT00000090973
Position:
Human AssemblyChrPosition (strand)Source
Build 361221,966,676 - 221,967,176 (+)MPROMDB
RGD ID:6784845
Promoter ID:HG_KWN:7497
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:OTTHUMT00000090974,   OTTHUMT00000099222,   UC001HOC.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361222,010,836 - 222,011,336 (+)MPROMDB
RGD ID:6784846
Promoter ID:HG_KWN:7498
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562
Transcripts:OTTHUMT00000090976,   OTTHUMT00000090977,   OTTHUMT00000090979,   OTTHUMT00000090980
Position:
Human AssemblyChrPosition (strand)Source
Build 361222,025,371 - 222,026,012 (+)MPROMDB
RGD ID:6859076
Promoter ID:EPDNEW_H2702
Type:initiation region
Name:CAPN2_2
Description:calpain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2703  EPDNEW_H2704  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,701,597 - 223,701,657EPDNEW
RGD ID:6859078
Promoter ID:EPDNEW_H2703
Type:initiation region
Name:CAPN2_3
Description:calpain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2702  EPDNEW_H2704  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,712,402 - 223,712,462EPDNEW
RGD ID:6859080
Promoter ID:EPDNEW_H2704
Type:initiation region
Name:CAPN2_1
Description:calpain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H2702  EPDNEW_H2703  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381223,712,539 - 223,712,599EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1479 AgrOrtholog
COSMIC CAPN2 COSMIC
Ensembl Genes ENSG00000162909 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000295006 ENTREZGENE
  ENST00000295006.6 UniProtKB/Swiss-Prot
  ENST00000433674 ENTREZGENE
  ENST00000433674.6 UniProtKB/Swiss-Prot
  ENST00000434648.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000162909 GTEx
HGNC ID HGNC:1479 ENTREZGENE
Human Proteome Map CAPN2 Human Proteome Map
InterPro C2_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_cysteine_protease UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_domain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calpain_III_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFh_PEF_CAPN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C2_calpain_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:824 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 824 ENTREZGENE
OMIM 114230 OMIM
PANTHER CALPAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10183:SF268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26060 PharmGKB
PRINTS CALPAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CALPAIN_CAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THIOL_PROTEASE_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART calpain_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CysPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49758 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6NDG7 ENTREZGENE
  B2RCM3 ENTREZGENE, UniProtKB/TrEMBL
  B4DN77 ENTREZGENE, UniProtKB/TrEMBL
  B7ZA96 ENTREZGENE
  C9JWY7_HUMAN UniProtKB/TrEMBL
  CAN2_HUMAN UniProtKB/Swiss-Prot
  E7ES58 ENTREZGENE
  P17655 ENTREZGENE
  Q16738 ENTREZGENE
  Q59EF6_HUMAN UniProtKB/TrEMBL
  Q6PJT3 ENTREZGENE
  Q8WU26 ENTREZGENE
  Q9HBB1 ENTREZGENE
UniProt Secondary A6NDG7 UniProtKB/Swiss-Prot
  B7ZA96 UniProtKB/Swiss-Prot
  E7ES58 UniProtKB/Swiss-Prot
  Q16738 UniProtKB/Swiss-Prot
  Q6PJT3 UniProtKB/Swiss-Prot
  Q8WU26 UniProtKB/Swiss-Prot
  Q9HBB1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 CAPN2  calpain 2    calpain 2, (m/II) large subunit  Symbol and/or name change 5135510 APPROVED