CAPN2 (calpain 2, (m/II) large subunit)

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Keyword

Gene: CAPN2 (calpain 2, (m/II) large subunit) Homo sapiens

Symbol:

CAPN2

Name:

calpain 2, (m/II) large subunit

Description:

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

calcium-activated neutral proteinase 2; calpain 2; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain large polypeptide L2; calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; calpain-2 large subunit; CANP 2; CANP2; CANPL2; CANPml; FLJ39928; M-calpain; mCANP; millimolar-calpain; OTTHUMP00000035497

Orthologs:

Mus musculus : Capn2 (calpain 2) MGI
Rattus norvegicus : Capn2 (calpain 2, (m/II) large subunit)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	1	230,684,735 - 230,759,211	+	NCBI
Human Genome Assembly HuRef	1	194,501,759 - 194,576,134	+	NCBI
Human Genome Assembly GRCh37	1	223,889,295 - 223,963,720	+	NCBI
Human Genome Assembly Build 36	1	221,966,742 - 222,030,343	+	NCBI
Human Cytogenetic Map	1	q41-q42		NCBI
Human Genome Assembly	1	220,206,935 - 220,270,453		NCBI