(1->4)-beta-D-glucan multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AKR1B1 mRNA CTD PMID:36331819 (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactions EXP 6480464 [zopolrestat results in decreased activity of AKR1B1 protein] inhibits the reaction [Antigens more ... CTD PMID:21334316 (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid decreases activity EXP 6480464 zopolrestat results in decreased activity of AKR1B1 protein CTD PMID:21334316 (E)-cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 (E,E)-2,4-hexadienal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2 more ... CTD PMID:21329684 and PMID:9890881 (R)-acetoin increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Acetoin CTD PMID:23295224 (R)-acetoin multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2 more ... CTD PMID:23295224 (R,R,R)-alpha-tocopherol increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 alpha-Tocopherol results in increased expression of AKR1B1 mRNA CTD PMID:16908007 1,2-dimethylhydrazine multiple interactions ISO Akr1b1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of AKR1B1 mRNA] CTD PMID:22206623 1,2-naphthoquinone increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 1 and 2-naphthoquinone CTD PMID:10510318 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of AKR1B1 mRNA CTD PMID:20566472 1-naphthyl isothiocyanate increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of AKR1B1 mRNA CTD PMID:25380136 16-Ketoestrone increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1B1 mRNA CTD PMID:20106945 and PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Akr1b1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1B1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1B1 mRNA CTD PMID:19684285 and PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Akr1b1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1B1 mRNA CTD PMID:22298810 and PMID:34747641 2,3-dimethoxynaphthalene-1,4-dione decreases expression EXP 6480464 2 more ... CTD PMID:17547211 2,4-Nonadienal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2 and 4-nonadienal CTD PMID:9890881 2-acetamidofluorene increases expression ISO Akr1b1 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of AKR1B1 mRNA CTD PMID:17317680 2-hexenal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-hexenal and AKR1B1 protein results in increased reduction of 2-hexenal metabolite CTD PMID:21329684 and PMID:9890881 2-hexenal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 2-hexenal CTD PMID:11306073 2-hydroxypropanoic acid increases expression EXP 6480464 Lactic Acid results in increased expression of AKR1B1 mRNA CTD PMID:20566472 2-palmitoylglycerol increases expression EXP 6480464 2-palmitoylglycerol results in increased expression of AKR1B1 mRNA CTD PMID:37199045 2-pentenal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-pentenal CTD PMID:9890881 2-pentenal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 2-pentenal CTD PMID:11306073 3,4-dihydroxybenzoic acid multiple interactions ISO Akr1b1 (Mus musculus) 6480464 protocatechuic acid inhibits the reaction [Galactose results in increased expression of AKR1B1 mRNA] CTD PMID:22687555 3-chloropropane-1,2-diol decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in decreased expression of AKR1B1 mRNA CTD PMID:28522335 3-chloropropane-1,2-diol increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of AKR1B1 protein CTD PMID:34915118 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AKR1B1 mRNA CTD PMID:28628672 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of AKR1B1 mRNA CTD PMID:24848799 4,4'-diaminodiphenylmethane increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AKR1B1 mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane increases expression ISO Akr1b1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AKR1B1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AKR1B1 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of AKR1B1 protein CTD PMID:34186270 4-hydroxy-2-octenal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 4-hydroxy-2-octenal CTD PMID:11306073 4-hydroxy-2-octenal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 4-hydroxy-2-octenal CTD PMID:9890881 4-hydroxyhexenal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 4-hydroxy-2-hexenal CTD PMID:11306073 4-hydroxyhexenal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 4-hydroxy-2-hexenal CTD PMID:9890881 4-hydroxynon-2-enal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 4-hydroxy-2-nonenal CTD PMID:11306073 4-hydroxynon-2-enal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal and AKR1B1 protein results in increased reduction of 4-hydroxy-2-nonenal metabolite CTD PMID:10510318 more ... 4-hydroxyphenyl retinamide decreases expression ISO Akr1b1 (Mus musculus) 6480464 Fenretinide results in decreased expression of AKR1B1 mRNA CTD PMID:28973697 4-nitrobenzaldehyde increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 4-nitrobenzaldehyde CTD PMID:10510318 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Uric Acid results in increased expression of AKR1B1 mRNA] CTD PMID:30651350 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP 6480464 Uric Acid results in increased expression of AKR1B1 mRNA CTD PMID:30651350 9,10-phenanthroquinone increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 9 and 10-phenanthrenequinone CTD PMID:10510318 9,10-phenanthroquinone multiple interactions EXP 6480464 AKR1B1 protein results in increased reduction of and affects the activity of 9 and 10-phenanthrenequinone CTD PMID:21910479 acetamide increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 acetamide results in increased expression of AKR1B1 mRNA CTD PMID:31881176 acetoin increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Acetoin CTD PMID:23295224 acetoin multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2 more ... CTD PMID:23295224 acrolein affects reduction EXP 6480464 AKR1B1 protein affects the reduction of Acrolein CTD PMID:11306073 acrolein increases expression ISO Akr1b1 (Mus musculus) 6480464 Acrolein results in increased expression of AKR1B1 protein CTD PMID:28482051 acrolein increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Acrolein and AKR1B1 protein results in increased reduction of Acrolein metabolite CTD PMID:10510318 more ... aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of AKR1B1 protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of AKR1B1 mRNA CTD PMID:22100608 more ... aldehydo-D-glucose multiple interactions EXP 6480464 AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol] CTD PMID:25451566 aldehydo-D-glucose increases expression ISO Akr1b1 (Mus musculus) 6480464 Glucose results in increased expression of AKR1B1 mRNA and Glucose results in increased expression of AKR1B1 protein CTD PMID:16805838 all-trans-4-oxoretinal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 4-oxoretinaldehyde CTD PMID:19014918 all-trans-dehydroretinal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of dehydroretinal CTD PMID:19014918 all-trans-retinal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Retinaldehyde CTD PMID:19014918 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of AKR1B1 mRNA CTD PMID:33167477 all-trans-retinol decreases response to substance EXP 6480464 AKR1B1 protein results in decreased susceptibility to Vitamin A and AKR1B1 protein results in decreased susceptibility to Vitamin A metabolite CTD PMID:19014918 alpha-D-galactose increases expression ISO Akr1b1 (Mus musculus) 6480464 Galactose results in increased expression of AKR1B1 mRNA CTD PMID:22687555 alpha-D-galactose multiple interactions ISO Akr1b1 (Mus musculus) 6480464 protocatechuic acid inhibits the reaction [Galactose results in increased expression of AKR1B1 mRNA] CTD PMID:22687555 alpha-hexylcinnamaldehyde increases expression EXP 6480464 hexyl cinnamic aldehyde results in increased expression of AKR1B1 mRNA CTD PMID:20566472 ammonium chloride affects expression ISO Akr1b1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of AKR1B1 mRNA CTD PMID:16483693 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA] CTD PMID:17640564 antimony(0) decreases expression EXP 6480464 Antimony results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 antimycin A decreases expression EXP 6480464 Antimycin A results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Uric Acid results in increased expression of AKR1B1 mRNA] CTD PMID:30651350 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of AKR1B1 mRNA and aristolochic acid I results in increased expression of AKR1B1 protein CTD PMID:33212167 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 azoxystrobin decreases expression EXP 6480464 azoxystrobin results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 Bandrowski's base increases expression EXP 6480464 Bandrowski's base results in increased expression of AKR1B1 mRNA CTD PMID:20566472 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 benzo[a]pyrene increases expression ISO Akr1b1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of AKR1B1 mRNA CTD PMID:20127859 and PMID:22228805 benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of AKR1B1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of AKR1B1 mRNA CTD PMID:20106945 more ... benzo[a]pyrene increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of AKR1B1 protein CTD PMID:16456883 benzo[a]pyrene multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:16456883 and PMID:18711122 Benzo[a]pyrene-7,8-diol multiple interactions EXP 6480464 [AKR1B1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 and 8-dihydrodiol CTD PMID:21910479 benzo[a]pyrene-7,8-dione multiple interactions EXP 6480464 [AKR1B1 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 and 8-dione CTD PMID:21910479 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of AKR1B1 mRNA CTD PMID:17690111 Benzo[k]fluoranthene increases expression ISO Akr1b1 (Mus musculus) 6480464 benzo(k)fluoranthene results in increased expression of AKR1B1 mRNA CTD PMID:26377693 benzoic acid increases expression EXP 6480464 Benzoic Acid results in increased expression of AKR1B1 mRNA CTD PMID:20566472 benzyl alcohol increases oxidation EXP 6480464 AKR1B1 protein results in increased oxidation of Benzyl Alcohol CTD PMID:17194029 bisphenol A multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [Fructose co-treated with bisphenol A] results in increased expression of AKR1B1 protein CTD PMID:26930160 bisphenol A decreases expression ISO Akr1b1 (Mus musculus) 6480464 bisphenol A results in decreased expression of AKR1B1 protein CTD PMID:35999755 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AKR1B1 protein CTD PMID:34186270 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of AKR1B1 mRNA CTD PMID:30903817 bisphenol A increases methylation ISO Akr1b1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of AKR1B1 gene CTD PMID:28505145 bisphenol A decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of AKR1B1 mRNA and bisphenol A results in decreased expression of AKR1B1 protein CTD PMID:20219716 and PMID:34947998 bisphenol A increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of AKR1B1 mRNA CTD PMID:25181051 Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of AKR1B1 protein CTD PMID:34186270 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of AKR1B1 protein CTD PMID:34186270 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of AKR1B1 mRNA and Bortezomib results in increased expression of AKR1B1 protein CTD PMID:21215737 butanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of butyraldehyde CTD PMID:11306073 butanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of butyraldehyde CTD PMID:9890881 butane-2,3-diol multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2 and 3-butylene glycol CTD PMID:23295224 butane-2,3-dione increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Diacetyl CTD PMID:23295224 butane-2,3-dione multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin CTD PMID:23295224 cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of AKR1B1 protein CTD PMID:24527689 candesartan decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 candesartan results in decreased expression of AKR1B1 mRNA CTD PMID:14871019 capecitabine decreases response to substance EXP 6480464 AKR1B1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 carbon nanotube affects expression EXP 6480464 Nanotubes and Carbon affects the expression of AKR1B1 protein CTD PMID:22001959 carbon nanotube increases expression ISO Akr1b1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of AKR1B1 mRNA CTD PMID:25554681 carboplatin increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Carboplatin results in increased expression of AKR1B1 mRNA CTD PMID:18172885 carmustine affects response to substance EXP 6480464 AKR1B1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 cefaloridine increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Cephaloridine results in increased expression of AKR1B1 mRNA CTD PMID:18172885 ceruletide increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Ceruletide results in increased expression of AKR1B1 protein CTD PMID:18024178 CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to AKR1B1 gene] CTD PMID:28238834 chlordecone decreases expression ISO Akr1b1 (Mus musculus) 6480464 Chlordecone results in decreased expression of AKR1B1 mRNA CTD PMID:33711761 choline multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B1 mRNA CTD PMID:20938992 chromium atom decreases expression EXP 6480464 Chromium results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 chromium(6+) affects expression ISO Akr1b1 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of AKR1B1 mRNA CTD PMID:28472532 cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of AKR1B1 protein CTD PMID:16803524 cisplatin increases phosphorylation ISO Akr1b1 (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of AKR1B1 protein CTD PMID:22006019 cisplatin increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of AKR1B1 mRNA CTD PMID:18172885 clobetasol increases expression ISO Akr1b1 (Mus musculus) 6480464 Clobetasol results in increased expression of AKR1B1 mRNA CTD PMID:27462272 Clofop increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of fenofibric acid CTD PMID:27599626 copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of AKR1B1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of AKR1B1 mRNA CTD PMID:20971185 and PMID:30911355 copper atom decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Copper deficiency results in decreased expression of AKR1B1 protein and Copper results in decreased expression of AKR1B1 mRNA CTD PMID:18993053 and PMID:30556269 copper atom increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Copper results in increased expression of AKR1B1 mRNA CTD PMID:22465980 copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of AKR1B1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of AKR1B1 mRNA CTD PMID:20971185 and PMID:30911355 copper(0) decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Copper deficiency results in decreased expression of AKR1B1 protein and Copper results in decreased expression of AKR1B1 mRNA CTD PMID:18993053 and PMID:30556269 copper(0) increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Copper results in increased expression of AKR1B1 mRNA CTD PMID:22465980 crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of AKR1B1 mRNA CTD PMID:29523930 crotonaldehyde increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-butenal and AKR1B1 protein results in increased reduction of 2-butenal metabolite CTD PMID:21329684 and PMID:9890881 curcumin increases expression ISO Akr1b1 (Mus musculus) 6480464 Curcumin results in increased expression of AKR1B1 mRNA CTD PMID:18200517 curcumin multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA] more ... CTD PMID:17640564 and PMID:18588981 curcumin increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Curcumin results in increased expression of AKR1B1 mRNA and Curcumin results in increased expression of AKR1B1 protein CTD PMID:17640564 more ... curcumin increases activity ISO Akr1b1 (Rattus norvegicus) 6480464 Curcumin results in increased activity of AKR1B1 protein CTD PMID:17640564 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of AKR1B1 mRNA CTD PMID:20106945 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of AKR1B1 mRNA CTD PMID:25562108 and PMID:27989131 D-glucitol multiple interactions EXP 6480464 AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol] CTD PMID:25451566 D-glucitol increases abundance EXP 6480464 AKR1B1 protein results in increased abundance of Sorbitol CTD PMID:25541468 D-glucose multiple interactions EXP 6480464 AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol] CTD PMID:25451566 D-glucose increases expression ISO Akr1b1 (Mus musculus) 6480464 Glucose results in increased expression of AKR1B1 mRNA and Glucose results in increased expression of AKR1B1 protein CTD PMID:16805838 D-glyceraldehyde increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Glyceraldehyde CTD PMID:19014918 daunorubicin increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Daunorubicin CTD PMID:10510318 decanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of decanaldehyde CTD PMID:11306073 decanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of decanaldehyde CTD PMID:9890881 deguelin decreases expression EXP 6480464 deguelin results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 dexamethasone decreases expression ISO Akr1b1 (Mus musculus) 6480464 Dexamethasone results in decreased expression of AKR1B1 protein CTD PMID:33567340 dexamethasone multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of AKR1B1 mRNA CTD PMID:24848799 dexamethasone multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AKR1B1 mRNA CTD PMID:28628672 dextran sulfate increases expression ISO Akr1b1 (Mus musculus) 6480464 Dextran Sulfate results in increased expression of AKR1B1 mRNA CTD PMID:35093514 dextran sulfate decreases expression ISO Akr1b1 (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of AKR1B1 protein CTD PMID:35999755 dextran sulfate multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AKR1B1 mRNA CTD PMID:29950665 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 dibenz[a,h]anthracene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 dibenz[a,h]anthracene multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 dibenzo[a,l]pyrene multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 dibutyl phthalate decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of AKR1B1 mRNA CTD PMID:21266533 dioxygen multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 AKR1B1 protein inhibits the reaction [Oxygen deficiency results in increased phosphorylation of EIF2A protein] and AKR1B1 protein inhibits the reaction [Oxygen deficiency results in increased phosphorylation of EIF2AK3 protein] CTD PMID:19041636 dioxygen multiple interactions ISO Akr1b1 (Mus musculus) 6480464 AKR1B1 protein promotes the reaction [Oxygen deficiency results in increased expression of TNF protein] and AKR1B1 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein] CTD PMID:30682331 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate decreases expression EXP 6480464 Antimony Potassium Tartrate results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression EXP 6480464 Antimony Potassium Tartrate results in increased expression of AKR1B1 mRNA CTD PMID:28713220 diquat decreases expression ISO Akr1b1 (Mus musculus) 6480464 Diquat results in decreased expression of AKR1B1 mRNA CTD PMID:36851058 disulfiram increases expression EXP 6480464 Disulfiram results in increased expression of AKR1B1 mRNA CTD PMID:20566472 diuron increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Diuron results in increased expression of AKR1B1 mRNA CTD PMID:21551480 and PMID:25152437 diuron decreases expression EXP 6480464 Diuron results in decreased expression of AKR1B1 mRNA CTD PMID:35967413 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1B1 mRNA CTD PMID:27188386 doxifluridine decreases response to substance EXP 6480464 AKR1B1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of AKR1B1 mRNA CTD PMID:29803840 doxorubicin multiple interactions EXP 6480464 AKR1B1 protein results in increased abundance of and results in increased susceptibility to Doxorubicin CTD PMID:37257577 doxorubicin increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of AKR1B1 protein CTD PMID:37257577 endosulfan increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of AKR1B1 mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of AKR1B1 protein CTD PMID:23301498 ethanol decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Ethanol results in decreased expression of AKR1B1 mRNA CTD PMID:15353170 ethanol affects splicing ISO Akr1b1 (Mus musculus) 6480464 Ethanol affects the splicing of AKR1B1 mRNA CTD PMID:30319688 eugenol increases expression EXP 6480464 Eugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 fenpyroximate decreases expression EXP 6480464 fenpyroximate results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 Fidarestat affects binding EXP 6480464 NADP binds to AKR1B1 protein binds to fidarestat CTD PMID:23295227 Fidarestat multiple interactions EXP 6480464 fidarestat binds to and results in decreased activity of AKR1B1 protein CTD PMID:23295227 fipronil increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 fipronil results in increased expression of AKR1B1 mRNA CTD PMID:23962444 fluoranthene multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [1 more ... CTD PMID:18711122 fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of AKR1B1 mRNA CTD PMID:17690111 flutamide increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of AKR1B1 protein CTD PMID:17311803 folic acid multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B1 mRNA more ... CTD PMID:20938992 and PMID:22206623 fonofos increases methylation EXP 6480464 Fonofos results in increased methylation of AKR1B1 promoter CTD PMID:22847954 fructosamine multiple interactions EXP 6480464 AKR1B1 protein promotes the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein] CTD PMID:30682331 fructose multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [Fructose co-treated with bisphenol A] results in increased expression of AKR1B1 protein CTD PMID:26930160 galactose multiple interactions ISO Akr1b1 (Mus musculus) 6480464 protocatechuic acid inhibits the reaction [Galactose results in increased expression of AKR1B1 mRNA] CTD PMID:22687555 galactose increases expression ISO Akr1b1 (Mus musculus) 6480464 Galactose results in increased expression of AKR1B1 mRNA CTD PMID:22687555 gentamycin increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of AKR1B1 mRNA CTD PMID:22061828 and PMID:33387578 glucose multiple interactions EXP 6480464 AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol] CTD PMID:25451566 glucose increases expression ISO Akr1b1 (Mus musculus) 6480464 Glucose results in increased expression of AKR1B1 mRNA and Glucose results in increased expression of AKR1B1 protein CTD PMID:16805838 glutathione increases glutathionylation EXP 6480464 Glutathione results in increased glutathionylation of AKR1B1 protein modified form CTD PMID:19061876 glutathione increases reduction EXP 6480464 Glutathione results in increased reduction of AKR1B1 protein modified form CTD PMID:19061876 glutathione affects binding EXP 6480464 AKR1B1 protein binds to Glutathione CTD PMID:11306073 glyceraldehyde increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Glyceraldehyde CTD PMID:19014918 glycine betaine decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Betaine results in decreased expression of AKR1B1 mRNA CTD PMID:26391144 glyoxal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Glyoxal CTD PMID:10510318 glyphosate decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Glyphosate results in decreased expression of AKR1B1 mRNA CTD PMID:26302742 hept-2-enal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-heptenal CTD PMID:9890881 heptanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of heptanal CTD PMID:11306073 heptanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of heptanal CTD PMID:9890881 hexanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of n-hexanal and AKR1B1 protein affects the reduction of n-hexanal analog CTD PMID:11306073 hexanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of n-hexanal CTD PMID:9890881 hexane increases expression EXP 6480464 n-hexane results in increased expression of AKR1B1 mRNA CTD PMID:20566472 hexane-2,3-dione increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2 and 3-hexanedione CTD PMID:10510318 and PMID:23295224 hexane-2,3-dione multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of 2 and 3-hexanedione] which results in increased chemical synthesis of Hexanones CTD PMID:23295224 hypochlorous acid increases expression ISO Akr1b1 (Mus musculus) 6480464 Hypochlorous Acid results in increased expression of AKR1B1 mRNA CTD PMID:19376150 indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AKR1B1 mRNA CTD PMID:28628672 inulin multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR1B1 mRNA CTD PMID:36331819 isatin increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Isatin CTD PMID:10510318 isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of AKR1B1 protein CTD PMID:32959892 L-ascorbic acid increases reduction EXP 6480464 Ascorbic Acid results in increased reduction of AKR1B1 protein modified form CTD PMID:19061876 L-methionine multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B1 mRNA CTD PMID:20938992 lipopolysaccharide multiple interactions EXP 6480464 [sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:21334316 lipopolysaccharide multiple interactions ISO Akr1b1 (Mus musculus) 6480464 Lipopolysaccharides inhibits the reaction [Sodium Chloride results in increased expression of AKR1B1 mRNA] CTD PMID:23867654 LY294002 multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA] CTD PMID:17640564 maneb multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of AKR1B1 mRNA CTD PMID:18386188 manganese(II) chloride increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 mercury atom decreases expression EXP 6480464 Mercury results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 mercury(0) decreases expression EXP 6480464 Mercury results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 methapyrilene increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of AKR1B1 mRNA CTD PMID:30467583 methyl salicylate increases expression EXP 6480464 methyl salicylate results in increased expression of AKR1B1 mRNA CTD PMID:20566472 methylglyoxal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Pyruvaldehyde CTD PMID:10510318 methylphenidate decreases expression ISO Akr1b1 (Mus musculus) 6480464 Methylphenidate results in decreased expression of AKR1B1 mRNA CTD PMID:22470460 methylseleninic acid increases expression EXP 6480464 methylselenic acid results in increased expression of AKR1B1 mRNA CTD PMID:18548127 microcystin-LR increases expression ISO Akr1b1 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of AKR1B1 mRNA CTD PMID:17654400 morphine decreases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Morphine results in decreased expression of AKR1B1 protein CTD PMID:23056601 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B1 mRNA CTD PMID:21215737 N-nitrosodiethylamine increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of AKR1B1 mRNA CTD PMID:19638242 N-nitrosodiethylamine increases expression ISO Akr1b1 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of AKR1B1 mRNA CTD PMID:24535843 N-nitrosodimethylamine increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of AKR1B1 mRNA CTD PMID:25380136 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 N-Nitrosopyrrolidine increases expression EXP 6480464 N-Nitrosopyrrolidine results in increased expression of AKR1B1 mRNA CTD PMID:32234424 NADP zwitterion multiple interactions EXP 6480464 [AKR1B1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:21910479 NADP zwitterion affects binding EXP 6480464 NADP binds to AKR1B1 protein binds to fidarestat CTD PMID:23295227 NADP zwitterion increases activity EXP 6480464 NADP results in increased activity of AKR1B1 protein CTD PMID:23295224 NADP(+) multiple interactions EXP 6480464 [AKR1B1 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:21910479 NADP(+) affects binding EXP 6480464 NADP binds to AKR1B1 protein binds to fidarestat CTD PMID:23295227 NADP(+) increases activity EXP 6480464 NADP results in increased activity of AKR1B1 protein CTD PMID:23295224 naphthalenes multiple interactions EXP 6480464 AKR1B1 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 nickel dichloride decreases expression EXP 6480464 nickel chloride results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of AKR1B1 mRNA CTD PMID:20566472 non-2-enal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 2-nonenal CTD PMID:11306073 non-2-enal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-nonenal CTD PMID:9890881 nonanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of nonanal and AKR1B1 protein affects the reduction of nonanal analog CTD PMID:11306073 nonanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of nonanal CTD PMID:9890881 O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of AKR1B1 mRNA CTD PMID:32234424 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of AKR1B1 mRNA CTD PMID:32905824 oct-2-enal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2-octenal CTD PMID:9890881 oct-2-enal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of 2-octenal CTD PMID:11306073 octanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of caprylic aldehyde CTD PMID:11306073 oxaliplatin multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AKR1B1 mRNA CTD PMID:25729387 ozone increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Ozone results in increased expression of AKR1B1 protein CTD PMID:33146391 ozone increases phosphorylation ISO Akr1b1 (Rattus norvegicus) 6480464 Ozone results in increased phosphorylation of AKR1B1 protein CTD PMID:33146391 paclitaxel increases response to substance EXP 6480464 AKR1B1 protein results in increased susceptibility to Paclitaxel CTD PMID:16734730 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of AKR1B1 mRNA CTD PMID:22230336 paraquat multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [Paraquat co-treated with Maneb] results in decreased expression of AKR1B1 mRNA CTD PMID:18386188 parathion increases methylation EXP 6480464 Parathion results in increased methylation of AKR1B1 promoter CTD PMID:22847954 pentanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of pentanal CTD PMID:11306073 pentanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of pentanal CTD PMID:9890881 pentane-2,3-dione increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of 2 and 3-pentanedione CTD PMID:23295224 pentane-2,3-dione multiple interactions EXP 6480464 [AKR1B1 protein results in increased reduction of 2 and 3-pentanedione] which results in increased chemical synthesis of Pentanones CTD PMID:23295224 perfluorooctane-1-sulfonic acid multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AKR1B1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR1B1 mRNA CTD PMID:36331819 phenethyl caffeate decreases activity EXP 6480464 caffeic acid phenethyl ester results in decreased activity of AKR1B1 protein CTD PMID:27163852 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of AKR1B1 mRNA CTD PMID:19084549 phenobarbital affects expression ISO Akr1b1 (Mus musculus) 6480464 Phenobarbital affects the expression of AKR1B1 mRNA CTD PMID:23091169 Phenylglyoxal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of Phenylglyoxal CTD PMID:10510318 picoxystrobin decreases expression EXP 6480464 picoxystrobin results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 pirinixic acid decreases activity EXP 6480464 pirinixic acid results in decreased activity of AKR1B1 protein CTD PMID:17194029 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 propan-2-ol increases expression EXP 6480464 2-Propanol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 propanal affects reduction EXP 6480464 AKR1B1 protein affects the reduction of propionaldehyde analog CTD PMID:11306073 propanal increases reduction EXP 6480464 AKR1B1 protein results in increased reduction of propionaldehyde CTD PMID:9890881 prostaglandin E2 multiple interactions EXP 6480464 [sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased secretion of Dinoprostone] more ... CTD PMID:21334316 pterostilbene multiple interactions ISO Akr1b1 (Mus musculus) 6480464 pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 mRNA] and pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 protein] CTD PMID:21355597 pyrimidifen decreases expression EXP 6480464 pyrimidifen results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 quercetin increases expression EXP 6480464 Quercetin results in increased expression of AKR1B1 mRNA CTD PMID:21632981 rac-lactic acid increases expression EXP 6480464 Lactic Acid results in increased expression of AKR1B1 mRNA CTD PMID:20566472 reactive oxygen species multiple interactions EXP 6480464 [sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:21334316 resveratrol increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 resveratrol results in increased expression of AKR1B1 mRNA CTD PMID:25905778 resveratrol multiple interactions ISO Akr1b1 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 mRNA] and Resveratrol inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 protein] CTD PMID:21355597 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 SB 203580 multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 SB 203580 inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA] CTD PMID:17640564 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1B1 mRNA CTD PMID:27188386 silicon dioxide increases secretion EXP 6480464 Silicon Dioxide analog results in increased secretion of AKR1B1 protein CTD PMID:25895662 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of AKR1B1 mRNA CTD PMID:12727804 sodium arsenite increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of AKR1B1 protein CTD PMID:16456883 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of AKR1B1 mRNA CTD PMID:34032870 sodium arsenite multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 Benzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of AKR1B1 protein] and sodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of AKR1B1 protein] CTD PMID:16456883 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AKR1B1 mRNA CTD PMID:20886546 and PMID:28713220 sodium chloride increases expression ISO Akr1b1 (Mus musculus) 6480464 Sodium Chloride results in increased expression of AKR1B1 mRNA CTD PMID:23867654 sodium chloride multiple interactions ISO Akr1b1 (Mus musculus) 6480464 Lipopolysaccharides inhibits the reaction [Sodium Chloride results in increased expression of AKR1B1 mRNA] CTD PMID:23867654 sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of AKR1B1 mRNA CTD PMID:20566472 sorbinil multiple interactions EXP 6480464 [sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:21334316 and PMID:28137510 sorbinil decreases activity EXP 6480464 sorbinil results in decreased activity of AKR1B1 protein CTD PMID:21334316 streptozocin multiple interactions EXP 6480464 Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:25541468 sulindac multiple interactions EXP 6480464 Sulindac analog binds to and results in decreased activity of AKR1B1 protein and Sulindac binds to and results in decreased activity of AKR1B1 protein CTD PMID:25532697 sulindac sulfone multiple interactions EXP 6480464 sulindac sulfone binds to and results in decreased activity of AKR1B1 protein CTD PMID:25532697 sunitinib decreases expression EXP 6480464 Sunitinib results in decreased expression of AKR1B1 mRNA CTD PMID:31533062 tebufenpyrad decreases expression EXP 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of AKR1B1 mRNA CTD PMID:33512557 temozolomide affects response to substance EXP 6480464 AKR1B1 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 temozolomide decreases expression EXP 6480464 Temozolomide results in decreased expression of AKR1B1 mRNA CTD PMID:31758290 terbufos increases methylation EXP 6480464 terbufos results in increased methylation of AKR1B1 promoter CTD PMID:22847954 thioacetamide increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of AKR1B1 mRNA CTD PMID:34492290 titanium dioxide decreases phosphorylation EXP 6480464 titanium dioxide results in decreased phosphorylation of AKR1B1 protein CTD PMID:21439344 titanium dioxide multiple interactions ISO Akr1b1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AKR1B1 mRNA CTD PMID:29950665 topotecan multiple interactions ISO Akr1b1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AKR1B1 mRNA CTD PMID:25729387 trans-isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of AKR1B1 mRNA CTD PMID:20566472 tributylstannane increases expression ISO Akr1b1 (Mus musculus) 6480464 tributyltin results in increased expression of AKR1B1 mRNA CTD PMID:24848799 Triptolide increases expression ISO Akr1b1 (Rattus norvegicus) 6480464 triptolide results in increased expression of AKR1B1 protein CTD PMID:32519852 triptonide increases expression ISO Akr1b1 (Mus musculus) 6480464 triptonide results in increased expression of AKR1B1 mRNA CTD PMID:33045310 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of AKR1B1 mRNA CTD PMID:25979313 valproic acid affects expression ISO Akr1b1 (Mus musculus) 6480464 Valproic Acid affects the expression of AKR1B1 mRNA CTD PMID:17963808 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of AKR1B1 mRNA CTD PMID:29501571 valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of AKR1B1 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of AKR1B1 mRNA and Valproic Acid results in increased expression of AKR1B1 protein CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1B1 mRNA CTD PMID:27188386 vitamin E increases expression EXP 6480464 Vitamin E results in increased expression of AKR1B1 mRNA CTD PMID:19244175 zearalenone decreases expression ISO Akr1b1 (Mus musculus) 6480464 Zearalenone results in decreased expression of AKR1B1 protein CTD PMID:36252740 zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of AKR1B1 mRNA CTD PMID:24714768
