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demethylase activity - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:demethylase activity
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Accession:GO:0032451 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a substrate.

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show annotations for term's descendants           Sort by:
demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA N-demethylation of benzphetamine, aminopyrine
N-demethylation of amitriptyline, erythromycin, diazapam, imipramine, lidocaine, morphine 		RGD PMID:11370669 PMID:10915793 RGD:2306679, RGD:2306680 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 enables ISO
IEA 		(PMID:2813353)
GO_REF:0000107 		RGD
Ensembl		 PMID:2813353 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 IDA RGD PMID:12971802 RGD:5129544 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IDA RGD PMID:18057719 PMID:12971802 RGD:2301699, RGD:5129544 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Kdm1a lysine demethylase 1A enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Mmachc metabolism of cobalamin associated C enables ISO
IBA 		(PMID:19801555)
GO_REF:0000033 		RGD
GO_Central		 PMID:19801555 GO_REF:0000033 NCBI chr 5:130,166,056...130,172,735
Ensembl chr 5:130,166,451...130,172,601 		JBrowse link
broad specificity oxidative DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables ISO
IEA
IBA 		(PMID:18603530), (PMID:30017583), (PMID:30392959)
GO_REF:0000107
(PMID:27027282)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:18603530 PMID:27027282 PMID:30017583 PMID:30392959 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase enables ISO
IEA
IBA 		(PMID:12486230), (PMID:16174769), (PMID:18432238), (PMID:20714506)
GO_REF:0000107
(PMID:16174769), (PMID:18519673)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:12486230 PMID:16174769 PMID:18432238 PMID:18519673 PMID:20714506 GO_REF:0000033 GO_REF:0000107 NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000116
GO_REF:0000107
(PMID:16174769)
(PMID:12486230), (PMID:16174769), (PMID:16858410), (PMID:20714506), (PMID:22055184) 		UniProt
RHEA
Ensembl
RGD		 PMID:12486230 PMID:16174769 PMID:16858410 PMID:20714506 PMID:22055184 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase enables ISO (PMID:30982744) RGD PMID:30982744 NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase enables ISS
IEA
ISO
IBA 		GO_REF:0000024
GO_REF:0000002
(PMID:18775698)
GO_REF:0000033
(PMID:18775698), (PMID:20376003) 		UniProt
InterPro
RGD
GO_Central		 PMID:18775698 PMID:20376003 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
cytosine C-5 DNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase enables ISO
IEA
IBA 		(PMID:18432238)
GO_REF:0000107
(PMID:16174769)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:16174769 PMID:18432238 GO_REF:0000033 GO_REF:0000107 NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISO (PMID:16174769) RGD PMID:16174769 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
FAD-dependent H3K4me/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO
IEA
IBA 		(PMID:24843136)
GO_REF:0000116
GO_REF:0000107
GO_REF:0000117
GO_REF:0000033
(PMID:20228790), (PMID:27292636) 		RGD
RHEA
Ensembl
UniProt
GO_Central		 PMID:20228790 PMID:24843136 PMID:27292636 GO_REF:0000033 GO_REF:0000107 GO_REF:0000116 GO_REF:0000117 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm1b lysine demethylase 1B enables ISO
IEA 		(PMID:23260659), (PMID:23266887), (PMID:23357850)
GO_REF:0000107
GO_REF:0000117
(PMID:19407342), (PMID:19727073)
(PMID:30970244) 		RGD
Ensembl
UniProt		 PMID:19407342 PMID:19727073 PMID:23260659 PMID:23266887 PMID:23357850 More... GO_REF:0000107 GO_REF:0000117 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800 		JBrowse link
histone demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxl19 F-box and leucine-rich repeat protein 19 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:182,356,899...182,380,839
Ensembl chr 1:182,360,830...182,380,083 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 NOT|enables IBA
ISO 		GO_REF:0000033
(PMID:20064376) 		GO_Central
RGD		 PMID:20064376 GO_REF:0000033 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:24498420) 		UniProt
Ensembl
RGD		 PMID:24498420 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
G Kdm1a lysine demethylase 1A enables ISO
IEA 		(PMID:16079795), (PMID:18066052), (PMID:19497860)
GO_REF:0000107 		RGD
Ensembl		 PMID:16079795 PMID:18066052 PMID:19497860 GO_REF:0000107 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm2a lysine demethylase 2A enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kdm2b lysine demethylase 2B enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355 		JBrowse link
G Kdm4a lysine demethylase 4A enables ISO (PMID:19144645) RGD PMID:19144645 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO
IEA 		(PMID:19144645)
GO_REF:0000107 		RGD
Ensembl		 PMID:19144645 GO_REF:0000107 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables ISO
IEA 		(PMID:18066052)
GO_REF:0000107
(PMID:19144645) 		RGD
Ensembl		 PMID:18066052 PMID:19144645 GO_REF:0000107 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO (PMID:19144645) RGD PMID:19144645 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Kdm6a lysine demethylase 6A enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kdm6b lysine demethylase 6B enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kdm7a lysine demethylase 7A enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf2 PHD finger protein 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
IEA
IBA 		(PMID:19843542)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:19843542 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
G Phf8l PHD finger protein 8 like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:12,194,437...12,200,509
Ensembl chr 7:12,194,441...12,200,446 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422 		JBrowse link
histone H3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm4a lysine demethylase 4A enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4c lysine demethylase 4C enables IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
histone H3K27me2/H3K27me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm6a lysine demethylase 6A enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:22949634) 		GO_Central
Ensembl
RGD		 PMID:22949634 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kdm6b lysine demethylase 6B enables ISO
IEA
IBA 		(PMID:28262558)
GO_REF:0000107
(PMID:17928865), (PMID:18716661), (PMID:23856522)
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:17928865 PMID:18716661 PMID:23856522 PMID:28262558 GO_REF:0000033 GO_REF:0000107 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kdm7a lysine demethylase 7A enables ISO
IEA 		(PMID:20023638), (PMID:20194436), (PMID:20622853)
GO_REF:0000107
(PMID:20194436) 		RGD
Ensembl		 PMID:20023638 PMID:20194436 PMID:20622853 GO_REF:0000107 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
IEA 		(PMID:20622853), (PMID:20622854)
GO_REF:0000107 		RGD
Ensembl		 PMID:20622853 PMID:20622854 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422 		JBrowse link
histone H3K36 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm2a lysine demethylase 2A enables ISO
IEA 		(PMID:20417597), (PMID:21187428), (PMID:28262558)
GO_REF:0000107 		RGD
Ensembl		 PMID:20417597 PMID:21187428 PMID:28262558 GO_REF:0000107 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kdm2b lysine demethylase 2B enables ISO (PMID:26237645)
(PMID:21540074) 		RGD PMID:21540074 PMID:26237645 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355 		JBrowse link
G Kdm4a lysine demethylase 4A enables ISO
IBA 		(PMID:16024779), (PMID:21914792)
GO_REF:0000033 		RGD
GO_Central		 PMID:16024779 PMID:21914792 GO_REF:0000033 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO
IEA 		(PMID:21914792)
GO_REF:0000107
(PMID:16738407) 		RGD
Ensembl		 PMID:16738407 PMID:21914792 GO_REF:0000107 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables ISO
IBA 		(PMID:21914792)
GO_REF:0000033 		RGD
GO_Central		 PMID:21914792 GO_REF:0000033 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm7a lysine demethylase 7A enables ISO
IEA 		(PMID:20622853)
GO_REF:0000107 		RGD
Ensembl		 PMID:20622853 GO_REF:0000107 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Kdm8 lysine demethylase 8 enables ISO
IBA
IEA
ISS 		(PMID:20457893)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024 		RGD
GO_Central
Ensembl
UniProt		 PMID:20457893 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:180,013,969...180,028,829
Ensembl chr 1:180,020,656...180,028,841 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
IEA 		(PMID:20208542), (PMID:20622853)
GO_REF:0000107 		RGD
Ensembl		 PMID:20208542 PMID:20622853 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IBA
ISO 		GO_REF:0000033
(PMID:19927124) 		GO_Central
RGD		 PMID:19927124 GO_REF:0000033 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
G Riox2 ribosomal oxygenase 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked enables ISO (PMID:22192413) RGD PMID:22192413 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422 		JBrowse link
histone H3K36me/H3K36me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Riox1 ribosomal oxygenase 1 enables IEA GO_REF:0000116
GO_REF:0000003 		RHEA
UniProt		 GO_REF:0000003 GO_REF:0000116 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
histone H3K4 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO
IEA 		(PMID:24217620)
GO_REF:0000107
(PMID:15620353), (PMID:24217620), (PMID:27292636) 		RGD
Ensembl		 PMID:15620353 PMID:24217620 PMID:27292636 GO_REF:0000107 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm1b lysine demethylase 1B enables ISO
IEA 		(PMID:19407342), (PMID:19727073)
GO_REF:0000107 		RGD
Ensembl		 PMID:19407342 PMID:19727073 GO_REF:0000107 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800 		JBrowse link
G Kdm5a lysine demethylase 5A enables ISO
IEA 		(PMID:18483221)
GO_REF:0000107 		RGD
Ensembl		 PMID:18483221 GO_REF:0000107 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
IEA 		(PMID:18048344), (PMID:24952722), (PMID:27214403), (PMID:28262558)
GO_REF:0000107
(PMID:17320160) 		RGD
Ensembl		 PMID:17320160 PMID:18048344 PMID:24952722 PMID:27214403 PMID:28262558 GO_REF:0000107 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Kdm5c lysine demethylase 5C enables ISO (PMID:17320160), (PMID:18078810), (PMID:28262558)
(PMID:23246292) 		RGD PMID:17320160 PMID:18078810 PMID:23246292 PMID:28262558 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870 		JBrowse link
G Kdm5d lysine demethylase 5D enables ISO (PMID:17320160) RGD PMID:17320160 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
G Riox2 ribosomal oxygenase 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:40,861,365...40,884,782
Ensembl chr11:40,860,774...40,884,574 		JBrowse link
histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) RGD PMID:19407342 PMID:19727073 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800 		JBrowse link
G Kdm5a lysine demethylase 5A enables ISO
IEA
IBA 		(PMID:18270511)
GO_REF:0000003
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:18270511 GO_REF:0000003 GO_REF:0000033 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
IEA
IBA 		(PMID:20228790), (PMID:20403335)
GO_REF:0000107
GO_REF:0000003
GO_REF:0000033 		RGD
Ensembl
UniProt
GO_Central		 PMID:20228790 PMID:20403335 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Kdm5c lysine demethylase 5C enables IBA
IEA 		GO_REF:0000033
GO_REF:0000003 		GO_Central
UniProt		 GO_REF:0000003 GO_REF:0000033 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870 		JBrowse link
G Kdm5d lysine demethylase 5D enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  Y:527,069...624,019
Ensembl chr  Y:530,401...624,018 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables ISO (PMID:19927124) RGD PMID:19927124 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
histone H3K9 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr HR, lysine demethylase and nuclear receptor corepressor enables IEA
IBA 		GO_REF:0000002
GO_REF:0000033 		InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Jmjd1c jumonji domain containing 1C enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122 		JBrowse link
G Kdm1a lysine demethylase 1A enables ISO
IEA 		(PMID:16079795), (PMID:20228790)
GO_REF:0000107 		RGD
Ensembl		 PMID:16079795 PMID:20228790 GO_REF:0000107 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm3a lysine demethylase 3A enables ISO
IEA
IBA 		(PMID:28262558)
GO_REF:0000107
GO_REF:0000033
MGI:3764891 (PMID:17938240), (PMID:17943087), (PMID:17991879)
GO_REF:0000002 		RGD
Ensembl
GO_Central
InterPro		 PMID:17938240 PMID:17943087 PMID:17991879 PMID:28262558 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdm3b lysine demethylase 3B enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628 		JBrowse link
G Kdm4a lysine demethylase 4A enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000117
(PMID:16738407) 		GO_Central
UniProt
RGD		 PMID:16738407 GO_REF:0000033 GO_REF:0000117 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO
IEA
IBA 		(PMID:28262558)
GO_REF:0000107
GO_REF:0000117
(PMID:16738407)
GO_REF:0000033 		RGD
Ensembl
UniProt
GO_Central		 PMID:16738407 PMID:28262558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables ISO
IEA
IBA 		(PMID:18066052), (PMID:28262558)
GO_REF:0000107
GO_REF:0000117
(PMID:16738407), (PMID:17938240)
GO_REF:0000033 		RGD
Ensembl
UniProt
GO_Central		 PMID:16738407 PMID:17938240 PMID:18066052 PMID:28262558 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO
IBA 		(PMID:25124442)
MGI:5051955 (PMID:16738407), (PMID:21293030), (PMID:24550317)
GO_REF:0000033 		RGD
GO_Central		 PMID:16738407 PMID:21293030 PMID:24550317 PMID:25124442 GO_REF:0000033 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
G Kdm7a lysine demethylase 7A enables ISO
IEA 		(PMID:20194436)
(PMID:20194436), (PMID:20622853)
GO_REF:0000107 		RGD
Ensembl		 PMID:20194436 PMID:20622853 GO_REF:0000107 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf2 PHD finger protein 2 enables ISO (PMID:21532585) RGD PMID:21532585 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208 		JBrowse link
G Phf8 PHD finger protein 8 enables IEA
ISO 		GO_REF:0000107
(PMID:20208542), (PMID:20346720), (PMID:20622853), (PMID:20622854) 		Ensembl
RGD		 PMID:20208542 PMID:20346720 PMID:20622853 PMID:20622854 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
histone H3K9me/H3K9me2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr HR, lysine demethylase and nuclear receptor corepressor enables IEA GO_REF:0000003
GO_REF:0000116 		UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Kdm3a lysine demethylase 3A enables ISO
IEA 		(PMID:16603237)
GO_REF:0000107
GO_REF:0000003
GO_REF:0000116 		RGD
Ensembl
UniProt
RHEA		 PMID:16603237 GO_REF:0000003 GO_REF:0000107 GO_REF:0000116 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdm7a lysine demethylase 7A enables IEA
ISO 		GO_REF:0000107
(PMID:20023638) 		Ensembl
RGD		 PMID:20023638 GO_REF:0000107 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf8 PHD finger protein 8 enables IEA
ISO 		GO_REF:0000107
(PMID:20023638) 		Ensembl
RGD		 PMID:20023638 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
histone H3K9me2/H3K9me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO (PMID:20833138) RGD PMID:20833138 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm4a lysine demethylase 4A enables ISO
IEA 		(PMID:21914792)
GO_REF:0000003 		RGD
UniProt		 PMID:21914792 GO_REF:0000003 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B enables ISO
IEA 		(PMID:21914792)
GO_REF:0000003 		RGD
UniProt		 PMID:21914792 GO_REF:0000003 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm4c lysine demethylase 4C enables ISO
IEA 		(PMID:17277772), (PMID:21914792)
GO_REF:0000003 		RGD
UniProt		 PMID:17277772 PMID:21914792 GO_REF:0000003 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818 		JBrowse link
G Kdm4d lysine demethylase 4D enables ISO
IEA 		(PMID:21914792)
GO_REF:0000003
GO_REF:0000116 		RGD
UniProt
RHEA		 PMID:21914792 GO_REF:0000003 GO_REF:0000116 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290 		JBrowse link
histone H3R2 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISO
IEA
ISS 		(PMID:17947579)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:17947579 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
histone H4K20 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm7a lysine demethylase 7A enables ISO
IEA 		(PMID:20622853)
GO_REF:0000107 		RGD
Ensembl		 PMID:20622853 GO_REF:0000107 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Phf2 PHD finger protein 2 enables ISO (PMID:22921934) RGD PMID:22921934 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208 		JBrowse link
G Phf8 PHD finger protein 8 enables ISO
IEA 		(PMID:20622853)
GO_REF:0000107 		RGD
Ensembl		 PMID:20622853 GO_REF:0000107 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
G Rsbn1 round spermatid basic protein 1 enables ISO
IEA 		(PMID:28867287)
GO_REF:0000107 		RGD
Ensembl		 PMID:28867287 GO_REF:0000107 NCBI chr 2:191,416,631...191,470,711
Ensembl chr 2:191,416,631...191,470,711 		JBrowse link
histone H4R3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISS
IBA
IEA
ISO 		GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:17947579), (PMID:24360279) 		UniProt
GO_Central
Ensembl
RGD		 PMID:17947579 PMID:24360279 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
mRNA N1-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000116
GO_REF:0000107
GO_REF:0000003
(PMID:26863196), (PMID:26863410) 		UniProt
RHEA
Ensembl
RGD		 PMID:26863196 PMID:26863410 GO_REF:0000003 GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
mRNA N6-methyladenosine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh5 alkB homolog 5, RNA demethylase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
GO_REF:0000116
(PMID:29279410), (PMID:35939687), (PMID:36859428)
(PMID:23177736), (PMID:24616105), (PMID:34048572), (PMID:35333330), (PMID:36944332), (PMID:37257451), (PMID:37369679), (PMID:37474102) 		UniProt
Ensembl
RHEA
RGD		 PMID:23177736 PMID:24616105 PMID:29279410 PMID:34048572 PMID:35333330 More... GO_REF:0000024 GO_REF:0000107 GO_REF:0000116 NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase enables ISS
IEA
IBA
ISO 		GO_REF:0000024
GO_REF:0000116
GO_REF:0000033
GO_REF:0000003
(PMID:25452335), (PMID:26457839), (PMID:26458103), (PMID:30197295) 		UniProt
RHEA
GO_Central
RGD		 PMID:25452335 PMID:26457839 PMID:26458103 PMID:30197295 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 GO_REF:0000116 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
oxidative RNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:18603530), (PMID:31188562) 		GO_Central
Ensembl
RGD		 PMID:18603530 PMID:31188562 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase enables ISO
IEA 		(PMID:16174769)
GO_REF:0000107 		RGD
Ensembl		 PMID:16174769 GO_REF:0000107 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000 		JBrowse link
G Alkbh5 alkB homolog 5, RNA demethylase enables IBA
IEA 		GO_REF:0000033
GO_REF:0000002 		GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000002
(PMID:18775698)
(PMID:18775698), (PMID:22002720), (PMID:28002401), (PMID:30197295) 		UniProt
InterPro
RGD		 PMID:18775698 PMID:22002720 PMID:28002401 PMID:30197295 GO_REF:0000002 GO_REF:0000024 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:24360279) 		UniProt
Ensembl
RGD		 PMID:24360279 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
protein demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISO
IEA 		(PMID:24498420)
GO_REF:0000107 		RGD
Ensembl		 PMID:24498420 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
G Kdm1a lysine demethylase 1A enables ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Riox1 ribosomal oxygenase 1 enables ISO
ISS 		(PMID:35210392)
GO_REF:0000024 		RGD
UniProt		 PMID:35210392 GO_REF:0000024 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250 		JBrowse link
sterol 14-demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp51 cytochrome P450, family 51 enables IDA
IEA
ISO 		GO_REF:0000116
GO_REF:0000003
(PMID:20149798) 		RHEA
UniProt
RGD		 PMID:20149798 PMID:7665087 PMID:7581240 GO_REF:0000003 GO_REF:0000116, RGD:1298863, RGD:2316902 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410 		JBrowse link
tRNA demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase enables ISO
IEA 		(PMID:27745969)
GO_REF:0000107 		RGD
Ensembl		 PMID:27745969 GO_REF:0000107 NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase enables ISO
ISS 		(PMID:30197295)
GO_REF:0000024 		RGD
UniProt		 PMID:30197295 GO_REF:0000024 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    catalytic activity 7309
      demethylase activity 42
        DNA demethylase activity + 5
        methylselenol demethylase activity 0
        oxidative RNA demethylase activity + 5
        protein demethylase activity + 30
        sterol 14-demethylase activity 1
        vanillate monooxygenase activity 0
paths to the root