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Term:
histone H4K20 demethylase activity
(GO:0035575)
Annotations:
Rat: (4)
Mouse: (4)
Human: (4)
Chinchilla: (4)
Bonobo: (4)
Dog: (4)
Squirrel: (4)
Pig: (4)
Naked Mole-rat: (4)
Green Monkey: (4)
Parent Terms
Term With Siblings
Child Terms
2-oxoglutarate-dependent dioxygenase activity
+
histone H4 demethylase activity
+
2'-deoxymugineic-acid 2'-dioxygenase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity
4-coumaroyl 2'-hydroxylase activity
5-methylcytosine dioxygenase activity
6-beta-hydroxyhyoscyamine epoxidase activity
[protein]-asparagine 3-dioxygenase activity
broad specificity oxidative DNA demethylase activity
clavaminate synthase activity
codeine O-demethylase activity
deacetoxycephalosporin-C hydroxylase activity
deoxyuridine 1'-dioxygenase activity
deoxyuridine 2'-dioxygenase activity
desacetoxyvindoline 4-hydroxylase activity
flavanone 3-dioxygenase activity
flavone synthase activity
flavonol synthase activity
gamma-butyrobetaine dioxygenase activity
gibberellin 2-beta-dioxygenase activity
gibberellin 20-oxidase activity
gibberellin 3-beta-dioxygenase activity
glutarate dioxygenase activity
histone H3K27me2/H3K27me3 demethylase activity
histone H3K36 demethylase activity
+
histone H3K4me/H3K4me2/H3K4me3 demethylase activity
histone H3K56me2/H3K56me3 demethylase activity
histone H3K9me/H3K9me2 demethylase activity
histone H3K9me2/H3K9me3 demethylase activity
histone H3R2 demethylase activity
histone H4K20 demethylase activity
Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
histone H4R3 demethylase activity
hyoscyamine (6S)-dioxygenase activity
L-gamma-glutamyl-L-propargylglycine hydroxylase activity
leucocyanidin oxygenase activity
mugineic-acid 3-dioxygenase activity
oxidative RNA demethylase activity
+
peptidyl-arginine 3-dioxygenase activity
peptidyl-aspartic acid 3-dioxygenase activity
peptidyl-histidine dioxygenase activity
peptidyl-lysine 3-dioxygenase activity
peptidyl-lysine 4-dioxygenase activity
peptidyl-lysine 5-dioxygenase activity
+
peptidyl-proline dioxygenase activity
+
phytanoyl-CoA dioxygenase activity
proline 3-hydroxylase activity
sulfonate dioxygenase activity
taurine dioxygenase activity
thebaine 6-O-demethylase activity
thymine dioxygenase activity
trimethyllysine dioxygenase activity
tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
Synonyms
Exact Synonyms:
histone H4-K20 demethylase activity ; histone H4-methyl-lysine-20 demethylase activity ; histone H4K20me demethylase activity ; histone demethylase activity (H4-K20 specific) ; histone demethylase activity (H4K20-specific)
Xrefs:
reactome:R-HSA-2172678 "PHF8 demethylates histone H4K20me1"
Definition Sources:
PMID:20622853
,
PMID:26214369
,
PMID:32209475