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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of telomere maintenance via telomerase
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Accession:GO:0032210 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.



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regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO UniProtKB:Q9NUX5 (PMID:26586433) RGD PMID:26586433 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO
IBA
UniProtKB:Q13315 (PMID:26586433)
GO_REF:0000033
RGD
GO_Central
PMID:26586433 GO_REF:0000033 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA
(PMID:19864690), (PMID:23685356)
GO_REF:0000033
RGD
GO_Central
PMID:19864690 PMID:23685356 GO_REF:0000033 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA
ISO
IBA
GO_REF:0000107
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063), (PMID:25172512)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:15181449 PMID:15380063 PMID:25172512 GO_REF:0000033 GO_REF:0000107 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461
JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO
IEA
(PMID:23935072)
GO_REF:0000107
RGD
Ensembl
PMID:23935072 GO_REF:0000107 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
ISO
GO_REF:0000107
(PMID:18082603)
Ensembl
RGD
PMID:18082603 GO_REF:0000107 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649), (PMID:23657261) RGD PMID:16522649 PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO
IEA
(PMID:11701125), (PMID:21119197)
GO_REF:0000107
RGD
Ensembl
PMID:11701125 PMID:21119197 GO_REF:0000107 NCBI chr15:38,097,896...38,157,143
Ensembl chr15:38,097,886...38,157,140
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449), (PMID:15632080) RGD PMID:15181449 PMID:15632080 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA
(PMID:22763445)
GO_REF:0000107
RGD
Ensembl
PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531
JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in ISO
IBA
(PMID:22763445)
GO_REF:0000033
RGD
GO_Central
PMID:22763445 GO_REF:0000033 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345) RGD PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984
JBrowse link
G Tp53 tumor protein p53 involved_in IEA
ISO
GO_REF:0000107
(PMID:10597287)
Ensembl
RGD
PMID:10597287 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:25467444)
Ensembl
RGD
PMID:25467444 GO_REF:0000107 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:22723415)
Ensembl
RGD
PMID:22723415 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (PMID:15240872)
(PMID:23685356), (PMID:25467444)
RGD PMID:15240872 PMID:23685356 PMID:25467444
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
JBrowse link
G Gch1 GTP cyclohydrolase 1 IMP RGD PMID:30690003 RGD:401717569 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO
IEA
(PMID:23935072)
GO_REF:0000107
RGD
Ensembl
PMID:23935072 GO_REF:0000107 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:22633954)
Ensembl
RGD
PMID:22633954 GO_REF:0000107 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786
JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein acts_upstream_of ISO (PMID:27510903) RGD PMID:27510903 NCBI chr16:22,837,583...22,868,320
Ensembl chr16:22,837,588...22,868,293
JBrowse link
G Nek7 NIMA-related kinase 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878 PMID:26950371 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO
IEA
(PMID:19740745)
GO_REF:0000107
RGD
Ensembl
PMID:19740745 GO_REF:0000107 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Tcp1 t-complex 1 acts_upstream_of ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (PMID:17982445) RGD PMID:17982445 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 acts_upstream_of ISO (PMID:23685356) RGD PMID:23685356 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        biosynthetic process 8469
          regulation of biosynthetic process 5507
            regulation of macromolecule biosynthetic process 5305
              regulation of DNA biosynthetic process 103
                regulation of telomere maintenance via telomerase 44
                  negative regulation of telomere maintenance via telomerase 20
                  positive regulation of telomere maintenance via telomerase 25
Path 2
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      metabolic process 11949
        primary metabolic process 10579
          nucleobase-containing compound metabolic process 5792
            nucleic acid metabolic process 5183
              DNA metabolic process 967
                DNA biosynthetic process 181
                  RNA-templated DNA biosynthetic process 64
                    telomere maintenance via telomerase 57
                      regulation of telomere maintenance via telomerase 44
                        negative regulation of telomere maintenance via telomerase 20
                        positive regulation of telomere maintenance via telomerase 25
paths to the root