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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of telomere maintenance via telomerase
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Accession:GO:0032211 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
Synonyms:exact_synonym: down regulation of telomere maintenance via telomerase activity;   downregulation of telomere maintenance via telomerase activity
 narrow_synonym: inhibition of telomere maintenance via telomerase


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negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA
UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063)
PMID:21873635
RGD PMID:15181449 PMID:15380063 PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461
JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557
JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940
JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:18082603)
Ensembl
RGD
PMID:18082603 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588
JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927
JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) RGD PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449) RGD PMID:15181449 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA
(PMID:22763445)
GO_REF:0000107
RGD
Ensembl
PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531
JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IBA
ISO
PMID:21873635
(PMID:22763445)
RGD PMID:22763445 PMID:21873635 RGD:13792537 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978), (PMID:17055345) RGD PMID:11971978 PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819
JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      negative regulation of metabolic process 3180
        negative regulation of macromolecule metabolic process 2956
          negative regulation of DNA metabolic process 133
            negative regulation of DNA biosynthetic process 44
              negative regulation of telomere maintenance via telomerase 20
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular metabolic process 10721
        cellular nitrogen compound metabolic process 6563
          nucleobase-containing compound metabolic process 5380
            nucleic acid metabolic process 4890
              DNA metabolic process 883
                regulation of DNA metabolic process 392
                  negative regulation of DNA metabolic process 133
                    negative regulation of telomere maintenance 36
                      negative regulation of telomere maintenance via telomere lengthening 27
                        negative regulation of telomere maintenance via telomerase 20
paths to the root