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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA biosynthetic process
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Accession:GO:0071897 term browser browse the term
Definition:The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
Synonyms:exact_synonym: DNA anabolism;   DNA biosynthesis;   DNA formation;   DNA synthesis

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DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Dntt DNA nucleotidylexotransferase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:239,856,391...239,888,283
Ensembl chr 1:239,856,391...239,888,282 		JBrowse link
G Lig1 DNA ligase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Lig3 DNA ligase 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
G Lig4 DNA ligase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040 		JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO MGI:3610732 (MGI:5603515|PMID:19458888) RGD PMID:19458888 MGI:5603515 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (MGI:4837988|PMID:20719856) RGD PMID:20719856 MGI:4837988 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Phb prohibitin acts_upstream_of_or_within ISO (MGI:3814796|PMID:18480465) RGD PMID:18480465 MGI:3814796 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in IMP
IEA		 GO_REF:0000108 GOC PMID:9099618 GO_REF:0000108, RGD:7247275 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348 		JBrowse link
G Polb DNA polymerase beta involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit involved_in IMP
ISO		 (MGI:6383350|PMID:11595739)
(PMID:11595739)		 RGD PMID:11595739 PMID:11959615 MGI:6383350, RGD:7247274 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit involved_in ISO (PMID:11595739)
(MGI:6383350|PMID:11595739)		 RGD PMID:11595739 MGI:6383350 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit involved_in ISO (PMID:11595739)
(MGI:6383350|PMID:11595739)		 RGD PMID:11595739 MGI:6383350 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit IMP RGD PMID:11959615 RGD:7247274 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Poll DNA polymerase lambda involved_in ISS
ISO		 GO_REF:0000024
(PMID:19806195)		 UniProt
RGD		 PMID:19806195 GO_REF:0000024 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662 		JBrowse link
G Polm DNA polymerase mu involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086 		JBrowse link
G Polq DNA polymerase theta involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5518963|PMID:23651497)		 Ensembl
RGD		 PMID:23651497 GO_REF:0000107 MGI:5518963 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sphk1 sphingosine kinase 1 acts_upstream_of_or_within ISO (MGI:5518963|PMID:23651497) RGD PMID:23651497 MGI:5518963 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:19701182), (PMID:9398860) RGD PMID:9398860 PMID:19701182 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tk1 thymidine kinase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
DNA synthesis involved in DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) RGD PMID:15750620 NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674 		JBrowse link
G Hrob homologous recombination factor with OB-fold involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31467087)		 UniProt
Ensembl
RGD		 PMID:31467087 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,206,017...87,222,483
Ensembl chr10:87,206,049...87,222,483 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit involved_in ISO (PMID:11470886) RGD PMID:11470886 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit involved_in ISS
ISO		 GO_REF:0000024
(PMID:1730053), (PMID:24191025), (PMID:3335506)		 UniProt
RGD		 PMID:1730053 PMID:3335506 PMID:24191025 GO_REF:0000024 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit involved_in ISO (PMID:1730053) RGD PMID:1730053 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Polh DNA polymerase eta involved_in ISO (PMID:17563354) RGD PMID:17563354 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5297784|PMID:17612497) RGD PMID:17612497 MGI:5297784 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Wrn WRN RecQ like helicase involved_in ISO (PMID:17563354) RGD PMID:17563354 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15670210)		 UniProt
Ensembl
RGD		 PMID:15670210 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659 		JBrowse link
DNA synthesis involved in UV-damage excision repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pola1 DNA polymerase alpha 1, catalytic subunit NOT|involved_in ISO
ISS		 (PMID:1730053)
GO_REF:0000024		 RGD
UniProt		 PMID:1730053 GO_REF:0000024 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5562498|PMID:23993650) RGD PMID:23993650 MGI:5562498 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
error-free translesion synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pold1 DNA polymerase delta 1, catalytic subunit involved_in ISO
IEA
ISS		 (PMID:24191025)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:24191025 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 involved_in ISO
IBA		 (PMID:24191025)
PMID:21873635		 RGD PMID:24191025 PMID:21873635 RGD:13792537 NCBI chr10:63,408,766...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
G Rev1 REV1, DNA directed polymerase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576 		JBrowse link
error-prone translesion synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pole2 DNA polymerase epsilon 2, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305 		JBrowse link
G Polh DNA polymerase eta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723 		JBrowse link
G Polk DNA polymerase kappa involved_in IBA
ISO		 PMID:21873635
(PMID:28297716)		 RGD PMID:28297716 PMID:21873635 RGD:13792537 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (PMID:24682820), (PMID:25746449), (PMID:28534480) RGD PMID:24682820 PMID:25746449 PMID:28534480 NCBI chr16:45,681,252...45,715,758
Ensembl chr16:45,681,326...45,715,565 		JBrowse link
G Rev1 REV1, DNA directed polymerase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:2157239|PMID:11711549)		 RGD PMID:11711549 PMID:21873635 MGI:2157239, RGD:13792537 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099 		JBrowse link
meiotic DNA repair synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata22 spermatogenesis associated 22 acts_upstream_of_or_within ISO MGI:5314540 (MGI:5314623|PMID:22011390) RGD PMID:22011390 MGI:5314623 NCBI chr10:57,945,272...57,963,081
Ensembl chr10:57,932,187...57,963,081 		JBrowse link
G Sycp1 synaptonemal complex protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:109542|MGI:3580000 (MGI:5315075|PMID:22164254)
PMID:21873635		 Ensembl
RGD		 PMID:22164254 PMID:21873635 GO_REF:0000107 MGI:5315075, RGD:13792537 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737 		JBrowse link
G Sycp3 synaptonemal complex protein 3 acts_upstream_of_or_within ISO MGI:105931|MGI:1913904 (MGI:5315075|PMID:22164254) RGD PMID:22164254 MGI:5315075 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Tex12 testis expressed 12 acts_upstream_of_or_within ISO MGI:109542|MGI:3811722 (MGI:5315075|PMID:22164254) RGD PMID:22164254 MGI:5315075 NCBI chr 8:50,908,161...50,913,205
Ensembl chr 8:50,909,052...50,913,217 		JBrowse link
negative regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:12070119)		 UniProt
RGD		 PMID:12070119 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Ahr aryl hydrocarbon receptor IDA RGD PMID:12193573 RGD:625678 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:11139470) RGD PMID:11139470 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek1 checkpoint kinase 1 IMP RGD PMID:12429946 RGD:2316115 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Dach1 dachshund family transcription factor 1 involved_in ISO (PMID:16980615) RGD PMID:16980615 NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922 		JBrowse link
G Dnajc2 DnaJ heat shock protein family (Hsp40) member C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:76992|PMID:7559602)		 Ensembl
RGD		 PMID:7559602 GO_REF:0000107 MGI:76992 NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IDA RGD PMID:10446064 RGD:7771571 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Gdf2 growth differentiation factor 2 involved_in ISO (PMID:19366699) RGD PMID:19366699 NCBI chr16:9,255,430...9,261,429
Ensembl chr16:9,255,430...9,261,429 		JBrowse link
G Gja1 gap junction protein, alpha 1 IDA RGD PMID:14702389 RGD:8662403 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:23271285 RGD:9831181 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Niban2 niban apoptosis regulator 2 involved_in ISO (PMID:14602737), (PMID:17569660), (PMID:20032057) RGD PMID:14602737 PMID:17569660 PMID:20032057 NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293 		JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:12746286 RGD:1580115 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Rgn regucalcin IMP RGD PMID:11500948 RGD:9590199 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Tp53 tumor protein p53 IMP RGD PMID:11502571 RGD:70312 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
negative regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers1 ceramide synthase 1 involved_in ISO (PMID:17548428) RGD PMID:17548428 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit NOT|involved_in ISO (PMID:18812185) RGD PMID:18812185 NCBI chr10:2,416,259...2,448,364 JBrowse link
G Mcrs1 microspherule protein 1 involved_in ISO (PMID:15044100) RGD PMID:15044100 NCBI chr 7:130,383,853...130,392,667
Ensembl chr 7:130,383,853...130,392,685 		JBrowse link
G Men1 menin 1 involved_in ISO (PMID:12837246) RGD PMID:12837246 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:16522649) RGD PMID:16522649 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pot1 protection of telomeres 1 involved_in IBA
ISO		 PMID:21873635
(PMID:15632080)		 RGD PMID:15632080 PMID:21873635 RGD:13792537 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:16556873 RGD:1580657 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:10597287) RGD PMID:10597287 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
negative regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (PMID:24528514) RGD PMID:24528514 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782 		JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA		 UniProtKB:Q9NUX5 (PMID:15181449), (PMID:15380063)
PMID:21873635		 RGD PMID:15181449 PMID:15380063 PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) RGD PMID:22763445 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Dcp2 decapping mRNA 2 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr18:36,750,732...36,787,067
Ensembl chr18:36,750,732...36,788,557 		JBrowse link
G Exosc10 exosome component 10 involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr 5:158,995,318...159,018,946
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G Gnl3l G protein nucleolar 3 like involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr  X:19,961,277...19,994,454
Ensembl chr  X:19,958,603...19,994,508 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:18082603)		 Ensembl
RGD		 PMID:18082603 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:18082603) RGD PMID:18082603 NCBI chr 3:90,111,643...90,151,644
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Pif1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) RGD PMID:23657261 NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200 		JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 involved_in ISO (PMID:11701125), (PMID:21119197) RGD PMID:11701125 PMID:21119197 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (PMID:19567472) RGD PMID:19567472 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO UniProtKB:Q96AP0 (PMID:15181449) RGD PMID:15181449 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stn1 STN1 subunit of CST complex involved_in ISO
IEA		 (PMID:22763445)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763445 GO_REF:0000107 NCBI chr 1:246,391,311...246,429,844
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Ten1 TEN1 subunit of CST complex involved_in IBA
ISO		 PMID:21873635
(PMID:22763445)		 RGD PMID:22763445 PMID:21873635 RGD:13792537 NCBI chr10:101,431,328...101,455,105
Ensembl chr10:101,431,328...101,453,052 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537 		JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO UniProtKB:O14746 (PMID:11971978) RGD PMID:11971978 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO (PMID:11971978), (PMID:17055345) RGD PMID:11971978 PMID:17055345 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 involved_in ISO (PMID:10581025), (PMID:15133513) RGD PMID:10581025 PMID:15133513 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
positive regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:19254952 RGD:5509898 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:23713944 RGD:7411623 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:17267544 RGD:2303063 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:16005543 RGD:5131269 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IMP RGD PMID:20439821 RGD:7829726 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:22446327 RGD:10401140 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Egf epidermal growth factor IDA RGD PMID:3093142 RGD:10395243 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO UniProtKB:Q9H3U7 (PMID:16774925) RGD PMID:16774925 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
ISS		 (PMID:21653700)
GO_REF:0000024		 RGD
UniProt		 PMID:21653700 GO_REF:0000024 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:16937468 RGD:9685728 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP RGD PMID:12721208 RGD:10045365 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO (PMID:2531289) RGD PMID:2531289 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISS
ISO		 GO_REF:0000024
(PMID:9924025)		 UniProt
RGD		 PMID:9924025 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) RGD PMID:17942966 MGI:5009390 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 IMP RGD PMID:12890786 RGD:7775030 NCBI chr  X:107,116,308...107,374,342
Ensembl chr  X:107,260,898...107,368,314 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:10644978), (PMID:10734101), (PMID:11788434), (PMID:12070119), (PMID:16530387), (PMID:17942966), (PMID:19019919)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10644978 PMID:10734101 PMID:11788434 PMID:12070119 PMID:16530387 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284758|PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 MGI:5284758 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5306299|PMID:17226786)		 UniProt
RGD		 PMID:17226786 GO_REF:0000024 MGI:5306299 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:21451101 RGD:10041071 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rgcc regulator of cell cycle involved_in IDA PMID:9756947 BHF-UCL PMID:9756947 RGD:633887 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Smoc2 SPARC related modular calcium binding 2 involved_in ISO UniProtKB:P09038|UniProtKB:P15692-4 (PMID:16774925) RGD PMID:16774925 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP PMID:16530387 UniProt PMID:16530387 RGD:8553998 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tnf tumor necrosis factor IDA RGD PMID:9395232 RGD:14696805 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO UniProtKB:Q9H3U7 (PMID:16774925) RGD PMID:16774925 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chtf18 chromosome transmission fidelity factor 18 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr19:34,782,005...34,792,306
Ensembl chr19:34,781,856...34,792,578 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Npm1 nucleophosmin 1 IDA RGD PMID:8123045 RGD:11535022 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in ISO (PMID:11595739) RGD PMID:11595739 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit involved_in ISO (PMID:10608893), (PMID:19837034), (PMID:19858216), (PMID:26123486) RGD PMID:10608893 PMID:19837034 PMID:19858216 PMID:26123486 NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008 		JBrowse link
G Rfc2 replication factor C subunit 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12930902)		 UniProt
RGD		 PMID:12930902 GO_REF:0000024 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557 		JBrowse link
G Rfc3 replication factor C subunit 3 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rfc4 replication factor C subunit 4 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rfc5 replication factor C subunit 5 involved_in ISO (PMID:12930902) RGD PMID:12930902 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
positive regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO
IBA		 (PMID:17237768)
PMID:21873635		 RGD PMID:17237768 PMID:21873635 RGD:13792537 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(MGI:5428344|PMID:22723415)		 Ensembl
RGD		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:25467444)
MGI:3849598 (MGI:3047190|PMID:15240872)		 RGD PMID:15240872 PMID:25467444 MGI:3047190
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:16545136) RGD PMID:16545136 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Grhl2 grainyhead-like transcription factor 2 involved_in ISO (PMID:19015635), (PMID:20938050) RGD PMID:19015635 PMID:20938050 NCBI chr 7:68,400,287...68,530,269
Ensembl chr 7:68,400,477...68,530,258 		JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Klf4 Kruppel like factor 4 involved_in ISO (PMID:20629177) RGD PMID:20629177 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:5810267|PMID:9637678) RGD PMID:9637678 MGI:5810267 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein involved_in ISO
IEA		 (PMID:27510903)
GO_REF:0000107		 RGD
Ensembl		 PMID:27510903 GO_REF:0000107 NCBI chr16:22,837,586...22,868,293
Ensembl chr16:22,837,588...22,868,293 		JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21531765)		 Ensembl
RGD		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Nvl nuclear VCP-like involved_in ISO
IBA		 (PMID:22226966)
PMID:21873635		 RGD PMID:22226966 PMID:21873635 RGD:13792537 NCBI chr13:92,851,023...92,906,749
Ensembl chr13:92,853,650...92,906,049 		JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 involved_in IMP
IBA		 PMID:12772192
PMID:21873635		 UniProt
GO_Central		 PMID:12772192 PMID:21873635 RGD:8553456, RGD:13792537 NCBI chr14:16,468,309...16,577,339
Ensembl chr14:16,468,459...16,577,314 		JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878) RGD PMID:26482878 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:15181449), (PMID:16043710), (PMID:17237768) RGD PMID:15181449 PMID:16043710 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)		 RGD PMID:10197982 PMID:19740745 MGI:5819359 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tnks tankyrase involved_in ISO (PMID:12782650) RGD PMID:12782650 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6189679|PMID:29804836)
(PMID:19179534), (PMID:23685356), (PMID:25467444), (PMID:29804836)		 UniProt
RGD		 PMID:19179534 PMID:23685356 PMID:25467444 PMID:29804836 GO_REF:0000024 MGI:6189679 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
positive regulation of telomerase RNA reverse transcriptase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 involved_in IDA PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D involved_in ISO (MGI:5438900|PMID:22633954) RGD PMID:22633954 MGI:5438900 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) RGD PMID:17237768 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) RGD PMID:26586427 MGI:5705431 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(MGI:5428344|PMID:22723415)		 Ensembl
RGD		 PMID:22723415 GO_REF:0000107 MGI:5428344 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 acts_upstream_of_or_within ISO MGI:3849598 (MGI:3047190|PMID:15240872) RGD PMID:15240872 MGI:3047190
G Fbxo4 F-box protein 4 involved_in ISO (PMID:16275645) RGD PMID:16275645 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) RGD PMID:23935072 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Nek2 NIMA-related kinase 2 involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Parn poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) RGD PMID:26482878 PMID:26950371 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pnkp polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) RGD PMID:21531765 NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206), (PMID:12781132), (PMID:17237768) RGD PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISO
IEA		 (PMID:21531765)
GO_REF:0000107		 RGD
Ensembl		 PMID:21531765 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Tcp1 t-complex 1 involved_in ISO (PMID:25467444) RGD PMID:25467444 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within ISO MGI:1857930 (MGI:3774867|PMID:17982445) RGD PMID:17982445 MGI:3774867 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tnks tankyrase involved_in ISO (PMID:11739745), (PMID:12782650), (PMID:18221737) RGD PMID:11739745 PMID:12782650 PMID:18221737 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) RGD PMID:19188702 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
regulation of DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:1933751 (MGI:3617096|PMID:11981756) RGD PMID:11981756 MGI:3617096 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Pdgfa platelet derived growth factor subunit A NOT|involved_in ISO
ISS		 (PMID:11788434), (PMID:19019919)
GO_REF:0000024		 RGD
UniProt		 PMID:11788434 PMID:19019919 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 involved_in ISO (MGI:5009204|PMID:10644978) RGD PMID:10644978 MGI:5009204 NCBI chr 1:181,048,622...181,057,036
Ensembl chr 1:181,048,623...181,056,579 		JBrowse link
G Tfdp1 transcription factor Dp-1 acts_upstream_of_or_within ISO (MGI:3525422|PMID:15448153) RGD PMID:15448153 MGI:3525422 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817 		JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein NOT|involved_in ISO (PMID:16479011) RGD PMID:16479011 NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250 		JBrowse link
regulation of telomerase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase NOT|involved_in ISO (PMID:26586427) RGD PMID:26586427 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Hmbox1 homeobox containing 1 involved_in ISO (PMID:23685356) RGD PMID:23685356 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323 		JBrowse link
G Nabp2 nucleic acid binding protein 2 NOT|involved_in ISO (PMID:25589350) RGD PMID:25589350 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 involved_in ISO (PMID:15169895) RGD PMID:15169895 NCBI chr15:30,690,503...30,792,868 JBrowse link
regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO UniProtKB:Q9NUX5 (PMID:26586433) RGD PMID:26586433 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Pot1 protection of telomeres 1 involved_in IBA
ISO		 PMID:21873635
UniProtKB:Q13315 (PMID:26586433)		 RGD PMID:26586433 PMID:21873635 RGD:13792537 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Pot1b protection of telomeres 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:9,670,355...9,728,624
Ensembl chr 9:9,670,362...9,728,532 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in ISO
IBA		 (PMID:19864690), (PMID:23685356)
PMID:21873635		 RGD PMID:19864690 PMID:23685356 PMID:21873635 RGD:13792537 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
RNA-dependent DNA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tep1 telomerase associated protein 1 involved_in IEA
IC		 GO_REF:0000108
PMID:9118230		 GOC PMID:9118230 GO_REF:0000108, RGD:1299082 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Terf2 telomeric repeat binding factor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr19:34,976,963...35,005,813
Ensembl chr19:34,977,471...35,005,819 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:9398860) RGD PMID:9398860 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acd ACD, shelterin complex subunit and telomerase recruitment factor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:33,586,739...33,589,481
Ensembl chr19:33,586,745...33,589,461 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 involved_in ISO
ISS		 GO:0090669 (PMID:23685356), (PMID:26950371), (PMID:29695869)
GO_REF:0000024		 RGD
UniProt		 PMID:23685356 PMID:26950371 PMID:29695869 GO_REF:0000024
G Gar1 GAR1 ribonucleoprotein involved_in ISS
ISO		 GO_REF:0000024
(PMID:29695869)		 UniProt
RGD		 PMID:29695869 GO_REF:0000024 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO (PMID:10197982) RGD PMID:10197982 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein involved_in ISO (PMID:29695869) RGD PMID:29695869 NCBI chr10:35,877,015...35,880,409
Ensembl chr10:35,877,054...35,882,545 		JBrowse link
G Nop10 NOP10 ribonucleoprotein involved_in ISO (PMID:29695869) RGD PMID:29695869 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 NOT|acts_upstream_of_or_within ISO MGI:109573 (MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:3045914 NCBI chr15:30,690,503...30,792,868 JBrowse link
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 acts_upstream_of_or_within ISO (PMID:11701125) RGD PMID:11701125 NCBI chr15:38,098,027...38,157,143
Ensembl chr15:38,097,886...38,157,140 		JBrowse link
G Pot1 protection of telomeres 1 involved_in ISO (PMID:12768206) RGD PMID:12768206 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Ptges3 prostaglandin E synthase 3 involved_in ISO
IBA		 (PMID:10197982), (PMID:19740745)
(MGI:5819359|PMID:10197982)
PMID:21873635		 RGD PMID:10197982 PMID:19740745 PMID:21873635 MGI:5819359, RGD:13792537 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:42,215,200...42,224,472
Ensembl chr  X:42,214,756...42,225,047 		JBrowse link
G Rad50 RAD50 double strand break repair protein involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:9705271)		 UniProt
RGD		 PMID:9705271 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rpa1 replication protein A1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Telo2 telomere maintenance 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698 		JBrowse link
G Tep1 telomerase associated protein 1 NOT|acts_upstream_of_or_within ISO MGI:2685589 (MGI:3045914|PMID:15169895) RGD PMID:15169895 MGI:3045914 NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Terc telomerase RNA component acts_upstream_of_or_within TAS
ISO		 MGI:1857930 (MGI:1097832|PMID:9335332) RGD PMID:9335332 PMID:10423530 MGI:1097832, RGD:1299555 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Terf1 telomeric repeat binding factor 1 involved_in ISO
IBA		 (PMID:9034193)
PMID:21873635
(PMID:23685356)		 RGD PMID:9034193 PMID:23685356 PMID:21873635 RGD:13792537 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Tert telomerase reverse transcriptase involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:16043710), (PMID:17940095), (PMID:19701182), (PMID:21531765), (PMID:29695869), (PMID:9443919), (PMID:9454332)		 UniProt
RGD		 PMID:9443919 PMID:9454332 PMID:16043710 PMID:17940095 PMID:19701182 More... GO_REF:0000024, RGD:13792537 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23685356), (PMID:29695869), (PMID:29804836)		 UniProt
RGD		 PMID:23685356 PMID:29695869 PMID:29804836 GO_REF:0000024 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
translesion synthesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO (PMID:20129063) RGD PMID:20129063 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Faap20 FA core complex associated protein 20 involved_in ISO
ISS		 (PMID:22266823)
GO_REF:0000024		 RGD
UniProt		 PMID:22266823 GO_REF:0000024 NCBI chr 5:165,808,370...165,815,291
Ensembl chr 5:165,808,657...165,815,333 		JBrowse link
G Parp10 poly (ADP-ribose) polymerase family, member 10 involved_in ISO (PMID:24695737) RGD PMID:24695737 NCBI chr 7:107,949,031...107,958,377
Ensembl chr 7:107,949,043...107,958,304 		JBrowse link
G Pclaf PCNA clamp associated factor involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:23000965)		 UniProt
RGD		 PMID:23000965 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994 		JBrowse link
G Pcna proliferating cell nuclear antigen involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:20129063)		 UniProt
RGD		 PMID:20129063 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Poli DNA polymerase iota involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3055735 (MGI:3695544|PMID:17114294)		 RGD PMID:17114294 PMID:21873635 MGI:3695544, RGD:13792537 NCBI chr18:64,116,774...64,134,373
Ensembl chr18:64,116,774...64,163,418 		JBrowse link
G Poln DNA polymerase nu involved_in ISO (PMID:19908865), (PMID:20102227) RGD PMID:19908865 PMID:20102227 NCBI chr14:76,579,983...76,752,460 JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO
IBA		 (PMID:24240614), (PMID:24267451)
PMID:21873635		 RGD PMID:24240614 PMID:24267451 PMID:21873635 RGD:13792537 NCBI chr16:45,681,252...45,715,758
Ensembl chr16:45,681,326...45,715,565 		JBrowse link
G Sprtn SprT-like N-terminal domain involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:22681887), (PMID:22902628), (PMID:23042605), (PMID:23042607)		 Ensembl
UniProt
RGD		 PMID:22681887 PMID:22902628 PMID:23042605 PMID:23042607 GO_REF:0000024 GO_REF:0000107 NCBI chr19:52,857,599...52,864,864
Ensembl chr19:52,857,866...52,864,864 		JBrowse link
G Vcp valosin-containing protein involved_in ISO
ISS		 (PMID:23042605)
GO_REF:0000024		 RGD
UniProt		 PMID:23042605 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (PMID:24657165) RGD PMID:24657165 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    metabolic process 11798
      biosynthetic process 6072
        cellular biosynthetic process 5914
          cellular macromolecule biosynthetic process 4990
            DNA biosynthetic process 183
              DNA amplification + 0
              DNA synthesis involved in DNA repair + 32
              DNA synthesis involved in DNA replication + 0
              RNA-dependent DNA biosynthetic process + 65
              negative regulation of DNA biosynthetic process + 44
              positive regulation of DNA biosynthetic process + 77
              regulation of DNA biosynthetic process + 125
Path 2
Term Annotations click to browse term
  biological_process 19494
    metabolic process 11798
      cellular metabolic process 10718
        heterocycle metabolic process 5520
          nucleobase-containing compound metabolic process 5378
            nucleic acid metabolic process 4888
              DNA metabolic process 882
                DNA biosynthetic process 183
                  DNA amplification + 0
                  DNA synthesis involved in DNA repair + 32
                  DNA synthesis involved in DNA replication + 0
                  RNA-dependent DNA biosynthetic process + 65
                  negative regulation of DNA biosynthetic process + 44
                  positive regulation of DNA biosynthetic process + 77
                  regulation of DNA biosynthetic process + 125
paths to the root