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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor receptor activity
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Accession:GO:0005021 term browser browse the term
Definition:Combining with a vascular endothelial growth factor (VEGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: VEGF receptor activity;   VEGF-activated receptor activity;   VEGFR activity;   vascular endothelial growth factor E-activated receptor activity;   vascular endothelial growth factor-activated receptor activity
 narrow_synonym: VEGF-A-activated receptor activity;   VEGF-B-activated receptor activity;   VEGF-C-activated receptor activity;   VEGF-D-activated receptor activity;   VEGF-E-activated receptor activity
 alt_id: GO:0036326;   GO:0036327;   GO:0036328;   GO:0036329;   GO:0036330



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vascular endothelial growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk anaplastic lymphoma kinase enables IEA UniProt GO_REF:0000003 NCBI chr17:72,174,206...72,911,719
Ensembl chr17:72,175,967...72,911,622
JBrowse link
G Axl AXL receptor tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Csf1r colony stimulating factor 1 receptor enables IEA UniProt GO_REF:0000003 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Ddr1 discoidin domain receptor family, member 1 enables IEA UniProt GO_REF:0000003 NCBI chr17:35,992,459...36,015,633
Ensembl chr17:35,992,459...36,015,513
JBrowse link
G Ddr2 discoidin domain receptor family, member 2 enables IEA UniProt GO_REF:0000003 NCBI chr 1:169,799,874...169,938,525
Ensembl chr 1:169,799,876...169,938,331
JBrowse link
G Egfr epidermal growth factor receptor enables IEA UniProt GO_REF:0000003 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Epha1 Eph receptor A1 enables IEA UniProt GO_REF:0000003 NCBI chr 6:42,335,421...42,350,249
Ensembl chr 6:42,335,421...42,350,202
JBrowse link
G Epha10 Eph receptor A10 enables IEA UniProt GO_REF:0000003 NCBI chr 4:124,775,408...124,811,594
Ensembl chr 4:124,774,692...124,811,593
JBrowse link
G Epha2 Eph receptor A2 enables IEA UniProt GO_REF:0000003 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695
JBrowse link
G Epha3 Eph receptor A3 enables IEA UniProt GO_REF:0000003 NCBI chr16:63,363,895...63,684,538
Ensembl chr16:63,363,897...63,684,538
JBrowse link
G Epha4 Eph receptor A4 enables IEA UniProt GO_REF:0000003 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725
JBrowse link
G Epha5 Eph receptor A5 enables IEA UniProt GO_REF:0000003 NCBI chr 5:84,199,024...84,565,677
Ensembl chr 5:84,202,620...84,565,241
JBrowse link
G Epha6 Eph receptor A6 enables IEA UniProt GO_REF:0000003 NCBI chr16:59,473,424...60,431,196
Ensembl chr16:59,473,846...60,425,894
JBrowse link
G Epha7 Eph receptor A7 enables IEA UniProt GO_REF:0000003 NCBI chr 4:28,811,840...28,969,391
Ensembl chr 4:28,813,131...28,967,499
JBrowse link
G Epha8 Eph receptor A8 enables IEA UniProt GO_REF:0000003 NCBI chr 4:136,656,729...136,684,170
Ensembl chr 4:136,656,730...136,684,127
JBrowse link
G Ephb1 Eph receptor B1 enables IEA UniProt GO_REF:0000003 NCBI chr 9:101,799,327...102,231,892
Ensembl chr 9:101,799,327...102,231,892
JBrowse link
G Ephb2 Eph receptor B2 enables IEA UniProt GO_REF:0000003 NCBI chr 4:136,374,850...136,563,637
Ensembl chr 4:136,374,850...136,563,299
JBrowse link
G Ephb3 Eph receptor B3 enables IEA UniProt GO_REF:0000003 NCBI chr16:21,023,530...21,042,054
Ensembl chr16:21,023,505...21,042,055
JBrowse link
G Ephb4 Eph receptor B4 enables IEA UniProt GO_REF:0000003 NCBI chr 5:137,348,371...137,372,784
Ensembl chr 5:137,348,371...137,376,931
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 enables IEA UniProt GO_REF:0000003 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 enables IEA UniProt GO_REF:0000003 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Fbxw7as1 F-box and WD-40 domain protein 7 antisense transcript 1 enables IDA (PMID:16293765) MGI PMID:16293765
G Fgfr1 fibroblast growth factor receptor 1 enables IEA UniProt GO_REF:0000003 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 enables IEA UniProt GO_REF:0000003 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 enables IEA UniProt GO_REF:0000003 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 enables IEA UniProt GO_REF:0000003 NCBI chr13:55,300,631...55,316,572
Ensembl chr13:55,300,453...55,316,572
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 enables ISO
IDA
IEA
ISS
IBA
(PMID:8356051) RGD
MGI
InterPro
GO_Central
UniProt
PMID:8356051 PMID:15785231 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1626621 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Flt3 FMS-like tyrosine kinase 3 enables IEA UniProt GO_REF:0000003 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
JBrowse link
G Flt4 FMS-like tyrosine kinase 4 enables ISO
IGI
ISS
IBA
(PMID:9247316) RGD
MGI
GO_Central
UniProt
PMID:9247316 PMID:11683876 GO_REF:0000008 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:727326 NCBI chr11:49,500,506...49,543,566
Ensembl chr11:49,500,090...49,543,566
JBrowse link
G Igf1r insulin-like growth factor I receptor enables IEA UniProt GO_REF:0000003 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Insr insulin receptor enables IEA UniProt GO_REF:0000003 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Insrr insulin receptor-related receptor enables IEA UniProt GO_REF:0000003 NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408
JBrowse link
G Kdr kinase insert domain protein receptor enables ISO
IDA
ISS
IBA
(PMID:8356051) RGD
MGI
GO_Central
UniProt
PMID:8356051 PMID:9442048 PMID:15785231 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1626621 RGD:729081 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382
JBrowse link
G Ltk leukocyte tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 2:119,581,807...119,590,912
Ensembl chr 2:119,581,801...119,590,912
JBrowse link
G Mertk MER proto-oncogene tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814
JBrowse link
G Met met proto-oncogene enables IEA UniProt GO_REF:0000003 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) enables IEA UniProt GO_REF:0000003 NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582
JBrowse link
G Musk muscle, skeletal, receptor tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 4:58,285,742...58,377,848
Ensembl chr 4:58,285,962...58,374,303
JBrowse link
G Nrp1 neuropilin 1 enables IMP
IBA
(PMID:21658587) BHF-UCL
GO_Central
PMID:21658587 GO_REF:0000033 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844
JBrowse link
G Nrp2 neuropilin 2 enables IEA InterPro GO_REF:0000002 NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 enables IEA UniProt GO_REF:0000003 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 enables IEA UniProt GO_REF:0000003 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
JBrowse link
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 enables IEA UniProt GO_REF:0000003 NCBI chr 7:77,825,711...78,228,865
Ensembl chr 7:77,825,707...78,387,760
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide enables ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide enables IEA UniProt GO_REF:0000003 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Ret ret proto-oncogene enables IEA UniProt GO_REF:0000003 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 enables IEA UniProt GO_REF:0000003 NCBI chr13:53,263,353...53,440,160
Ensembl chr13:53,263,348...53,440,160
JBrowse link
G Ros1 Ros1 proto-oncogene enables IEA UniProt GO_REF:0000003 NCBI chr10:51,920,959...52,071,494
Ensembl chr10:51,921,817...52,071,340
JBrowse link
G Tek TEK receptor tyrosine kinase enables IEA UniProt GO_REF:0000003 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 enables IEA UniProt GO_REF:0000003 NCBI chr 4:118,328,388...118,347,046
Ensembl chr 4:118,328,388...118,347,258
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase 3 enables IEA UniProt GO_REF:0000003 NCBI chr 2:119,628,123...119,648,585
Ensembl chr 2:119,628,214...119,648,585
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28792
    catalytic activity 5722
      catalytic activity, acting on a protein 2503
        protein kinase activity 596
          transmembrane receptor protein kinase activity 82
            transmembrane receptor protein tyrosine kinase activity 65
              vascular endothelial growth factor receptor activity 52
Path 2
Term Annotations click to browse term
  molecular_function 28792
    catalytic activity 5722
      transferase activity 2283
        transferase activity, transferring phosphorus-containing groups 915
          kinase activity 750
            protein kinase activity 596
              protein tyrosine kinase activity 146
                transmembrane receptor protein tyrosine kinase activity 65
                  vascular endothelial growth factor receptor activity 52
paths to the root