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Gene: Epha3 (Eph receptor A3) Mus musculus

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Symbol:

Epha3

Name:

Eph receptor A3

RGD ID:

68567

MGI Page

MGI

Description:

Enables ephrin receptor activity and growth factor binding activity. Involved in several processes, including axonal fasciculation; ephrin receptor signaling pathway; and synaptic membrane adhesion. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus; negative regulation of neuron projection development; and regulation of cell migration. Is active in GABA-ergic synapse and presynapse. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AW492086; Cek4; EK4; End; End3; EPH-like kinase 4; ephrin type-A receptor 3; ETK1; Hek; Hek4; Mek4; Tyr; Tyro4; tyrosine-protein kinase receptor ETK1; tyrosine-protein kinase TYRO4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPHA3 (EPH receptor A3)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Epha3 (Eph receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	EPHA7 (EPH receptor A7)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA1 (EPH receptor A1)	HGNC	OrthoMCL
Homo sapiens (human):	EPHB3 (EPH receptor B3)	HGNC	OrthoMCL
Homo sapiens (human):	EPHB6 (EPH receptor B6)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA2 (EPH receptor A2)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA4 (EPH receptor A4)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA10 (EPH receptor A10)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA8 (EPH receptor A8)	HGNC	OrthoMCL
Homo sapiens (human):	EPHB1 (EPH receptor B1)	HGNC	OrthoMCL
Homo sapiens (human):	EPHB4 (EPH receptor B4)	HGNC	OrthoMCL
Homo sapiens (human):	EPHB2 (EPH receptor B2)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA5 (EPH receptor A5)	HGNC	OrthoMCL
Homo sapiens (human):	EPHA6 (EPH receptor A6)	HGNC	OrthoMCL
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Epha3 (Eph receptor A3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	EPHA3 (EPH receptor A3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epha3 (eph receptor A3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	Eph	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	vab-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	epha3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	63,363,895 - 63,684,538 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	63,363,897 - 63,684,538 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	63,543,532 - 63,864,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	63,543,534 - 63,864,175 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	63,545,044 - 63,863,983 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	63,487,420 - 63,806,359 (-)	NCBI		MGSCv36	mm8
Celera	16	63,844,890 - 64,154,791 (-)	NCBI		Celera
Cytogenetic Map	16	C1.3	NCBI
cM Map	16	36.49	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	Fever		ISO	RGD:68389	1581943	mRNA, protein:decreased expression:lung, liver	RGD
Epha3	Mouse	pancreatic cancer		ISO	RGD:68566	2317720		RGD
Epha3	Mouse	Spinal Cord Injuries		ISO	RGD:68389	2301766		RGD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	atrial fibrillation		ISO	RGD:68566	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29892015\|PMID:30061737

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	(-)-demecolcine	decreases expression	ISO	RGD:68566	6480464	Demecolcine results in decreased expression of EPHA3 mRNA	CTD	PMID:23649840
Epha3	Mouse	(S)-nicotine	decreases expression	ISO	RGD:68566	6480464	Nicotine results in decreased expression of EPHA3 mRNA	CTD	PMID:18247414
Epha3	Mouse	1,2-dichloroethane	decreases expression	EXP		6480464	ethylene dichloride results in decreased expression of EPHA3 mRNA	CTD	PMID:28960355
Epha3	Mouse	17beta-estradiol	decreases expression	ISO	RGD:68566	6480464	Estradiol results in decreased expression of EPHA3 mRNA	CTD	PMID:21795739\|PMID:31614463
Epha3	Mouse	17beta-estradiol	multiple interactions	ISO	RGD:68566	6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA	CTD	PMID:20823114
Epha3	Mouse	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:68389	6480464	Tetrachlorodibenzodioxin results in decreased expression of EPHA3 mRNA	CTD	PMID:32109520
Epha3	Mouse	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	ISO	RGD:68389	6480464	2,3,7,8-tetrachlorodibenzofuran results in decreased expression of EPHA3 mRNA	CTD	PMID:32109520
Epha3	Mouse	2-naphthylamine	decreases expression	ISO	RGD:68566	6480464	2-Naphthylamine results in decreased expression of EPHA3 mRNA	CTD	PMID:18247414
Epha3	Mouse	acetamide	decreases expression	ISO	RGD:68389	6480464	acetamide results in decreased expression of EPHA3 mRNA	CTD	PMID:31881176
Epha3	Mouse	acrylamide	decreases expression	ISO	RGD:68566	6480464	Acrylamide results in decreased expression of EPHA3 mRNA	CTD	PMID:32763439
Epha3	Mouse	aldrin	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	all-trans-retinoic acid	decreases expression	ISO	RGD:68566	6480464	Tretinoin results in decreased expression of EPHA3 mRNA	CTD	PMID:21934132
Epha3	Mouse	allethrin	multiple interactions	ISO	RGD:68389	6480464	[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ...	CTD	PMID:34896426
Epha3	Mouse	alpha-amanitin	affects expression	EXP		6480464	Alpha-Amanitin affects the expression of EPHA3 mRNA	CTD	PMID:38531469
Epha3	Mouse	ammonium chloride	affects expression	ISO	RGD:68389	6480464	Ammonium Chloride affects the expression of EPHA3 mRNA	CTD	PMID:16483693
Epha3	Mouse	antimycin A	decreases expression	ISO	RGD:68566	6480464	Antimycin A results in decreased expression of EPHA3 mRNA	CTD	PMID:33512557
Epha3	Mouse	aristolochic acid A	decreases expression	ISO	RGD:68566	6480464	aristolochic acid I results in decreased expression of EPHA3 mRNA	CTD	PMID:33212167
Epha3	Mouse	arsenite(3-)	decreases expression	EXP		6480464	arsenite results in decreased expression of EPHA3 mRNA	CTD	PMID:33053406
Epha3	Mouse	atrazine	affects methylation	ISO	RGD:68389	6480464	Atrazine affects the methylation of EPHA3 gene	CTD	PMID:35440735
Epha3	Mouse	belinostat	increases expression	ISO	RGD:68566	6480464	belinostat results in increased expression of EPHA3 mRNA	CTD	PMID:26272509
Epha3	Mouse	benzo[a]pyrene	decreases expression	ISO	RGD:68566	6480464	Benzo(a)pyrene results in decreased expression of EPHA3 mRNA	CTD	PMID:18247414
Epha3	Mouse	bis(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:68389	6480464	[Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of EPHA3 mRNA	CTD	PMID:25031359
Epha3	Mouse	bisphenol A	decreases expression	ISO	RGD:68389	6480464	bisphenol A results in decreased expression of EPHA3 mRNA	CTD	PMID:25181051
Epha3	Mouse	bucladesine	multiple interactions	ISO	RGD:68566	6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA	CTD	PMID:20823114
Epha3	Mouse	cadmium atom	decreases expression	ISO	RGD:68566	6480464	Cadmium results in decreased expression of EPHA3 mRNA	CTD	PMID:33559965
Epha3	Mouse	cadmium dichloride	increases methylation	ISO	RGD:68389	6480464	Cadmium Chloride results in increased methylation of EPHA3 promoter	CTD	PMID:22457795
Epha3	Mouse	cadmium dichloride	increases expression	ISO	RGD:68389	6480464	Cadmium Chloride results in increased expression of EPHA3 mRNA	CTD	PMID:33453195
Epha3	Mouse	cocaine	affects expression	ISO	RGD:68389	6480464	Cocaine affects the expression of EPHA3 mRNA	CTD	PMID:15691709
Epha3	Mouse	cyhalothrin	multiple interactions	ISO	RGD:68389	6480464	[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ...	CTD	PMID:34896426
Epha3	Mouse	cypermethrin	multiple interactions	ISO	RGD:68389	6480464	[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ...	CTD	PMID:34896426
Epha3	Mouse	DDD	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	DDE	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	DDT	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	dibutyl phthalate	decreases expression	ISO	RGD:68389	6480464	Dibutyl Phthalate results in decreased expression of EPHA3 mRNA	CTD	PMID:21266533
Epha3	Mouse	dieldrin	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	dioxygen	increases expression	ISO	RGD:68566	6480464	Oxygen deficiency results in increased expression of EPHA3 mRNA	CTD	PMID:24236059
Epha3	Mouse	diquat	decreases expression	EXP		6480464	Diquat results in decreased expression of EPHA3 mRNA	CTD	PMID:36851058
Epha3	Mouse	dorsomorphin	multiple interactions	ISO	RGD:68566	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ...	CTD	PMID:27188386
Epha3	Mouse	doxorubicin	increases expression	ISO	RGD:68566	6480464	Doxorubicin results in increased expression of EPHA3 mRNA	CTD	PMID:30031762
Epha3	Mouse	doxorubicin	decreases expression	ISO	RGD:68566	6480464	Doxorubicin results in decreased expression of EPHA3 mRNA	CTD	PMID:29803840
Epha3	Mouse	endosulfan	decreases expression	ISO	RGD:68389	6480464	Endosulfan results in decreased expression of EPHA3 mRNA	CTD	PMID:29391264
Epha3	Mouse	endrin	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	entinostat	decreases expression	ISO	RGD:68566	6480464	entinostat results in decreased expression of EPHA3 mRNA	CTD	PMID:27188386
Epha3	Mouse	ethyl methanesulfonate	decreases expression	ISO	RGD:68566	6480464	Ethyl Methanesulfonate results in decreased expression of EPHA3 mRNA	CTD	PMID:23649840
Epha3	Mouse	fenvalerate	multiple interactions	ISO	RGD:68389	6480464	[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ...	CTD	PMID:34896426
Epha3	Mouse	folic acid	decreases expression	EXP		6480464	Folic Acid results in decreased expression of EPHA3 mRNA	CTD	PMID:25629700
Epha3	Mouse	formaldehyde	decreases expression	ISO	RGD:68566	6480464	Formaldehyde results in decreased expression of EPHA3 mRNA	CTD	PMID:23649840
Epha3	Mouse	furan	increases expression	ISO	RGD:68389	6480464	furan results in increased expression of EPHA3 mRNA	CTD	PMID:26194646
Epha3	Mouse	gamma-hexachlorocyclohexane	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	genistein	multiple interactions	ISO	RGD:68389	6480464	[Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of EPHA3 mRNA; [Genistein co-treated with more ...	CTD	PMID:21782745\|PMID:25031359
Epha3	Mouse	genistein	increases expression	EXP		6480464	Genistein results in increased expression of EPHA3 mRNA	CTD	PMID:32186404
Epha3	Mouse	Licochalcone B	decreases expression	ISO	RGD:68566	6480464	licochalcone B results in decreased expression of EPHA3 mRNA	CTD	PMID:33647349
Epha3	Mouse	lipopolysaccharide	multiple interactions	ISO	RGD:68566	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of EPHA3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ...	CTD	PMID:35811015
Epha3	Mouse	medroxyprogesterone acetate	multiple interactions	ISO	RGD:68566	6480464	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA	CTD	PMID:20823114
Epha3	Mouse	methoxychlor	multiple interactions	ISO	RGD:68389	6480464	[Genistein co-treated with Methoxychlor] results in decreased expression of EPHA3 mRNA	CTD	PMID:21782745
Epha3	Mouse	methyl methanesulfonate	decreases expression	ISO	RGD:68566	6480464	Methyl Methanesulfonate results in decreased expression of EPHA3 mRNA	CTD	PMID:23649840
Epha3	Mouse	methylmercury chloride	decreases expression	ISO	RGD:68566	6480464	methylmercuric chloride results in decreased expression of EPHA3 mRNA	CTD	PMID:28001369
Epha3	Mouse	N,N-diethyl-m-toluamide	multiple interactions	ISO	RGD:68389	6480464	[Permethrin co-treated with DEET] results in decreased methylation of EPHA3 gene	CTD	PMID:33148267
Epha3	Mouse	N-methyl-4-phenylpyridinium	decreases expression	ISO	RGD:68566	6480464	1-Methyl-4-phenylpyridinium results in decreased expression of EPHA3 mRNA	CTD	PMID:24810058
Epha3	Mouse	nicotine	decreases expression	ISO	RGD:68566	6480464	Nicotine results in decreased expression of EPHA3 mRNA	CTD	PMID:18247414
Epha3	Mouse	okadaic acid	decreases expression	ISO	RGD:68566	6480464	Okadaic Acid results in decreased expression of EPHA3 mRNA	CTD	PMID:38832940
Epha3	Mouse	ozone	decreases expression	ISO	RGD:68389	6480464	Ozone results in decreased expression of EPHA3 mRNA	CTD	PMID:16330353
Epha3	Mouse	panobinostat	multiple interactions	ISO	RGD:68566	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ...	CTD	PMID:27188386
Epha3	Mouse	panobinostat	increases expression	ISO	RGD:68566	6480464	panobinostat results in increased expression of EPHA3 mRNA	CTD	PMID:26272509
Epha3	Mouse	permethrin	multiple interactions	ISO	RGD:68389	6480464	[Permethrin co-treated with DEET] results in decreased methylation of EPHA3 gene	CTD	PMID:33148267
Epha3	Mouse	phenylmercury acetate	increases expression	ISO	RGD:68566	6480464	Phenylmercuric Acetate results in increased expression of EPHA3 mRNA	CTD	PMID:26272509
Epha3	Mouse	phenylmercury acetate	multiple interactions	ISO	RGD:68566	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Epha3	Mouse	picoxystrobin	decreases expression	ISO	RGD:68566	6480464	picoxystrobin results in decreased expression of EPHA3 mRNA	CTD	PMID:33512557
Epha3	Mouse	pioglitazone	multiple interactions	EXP		6480464	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA3 mRNA	CTD	PMID:27935865
Epha3	Mouse	ponatinib	decreases activity	ISO	RGD:68566	6480464	ponatinib analog results in decreased activity of EPHA3 protein; ponatinib results in decreased activity of more ...	CTD	PMID:19878872\|PMID:21561767
Epha3	Mouse	potassium dichromate	increases expression	EXP		6480464	Potassium Dichromate results in increased expression of EPHA3 mRNA	CTD	PMID:23608068
Epha3	Mouse	progesterone	increases expression	ISO	RGD:68566	6480464	Progesterone results in increased expression of EPHA3 mRNA	CTD	PMID:21795739
Epha3	Mouse	pyrethrins	decreases expression	ISO	RGD:68389	6480464	Pyrethrins results in decreased expression of EPHA3 protein	CTD	PMID:34896426
Epha3	Mouse	rofecoxib	decreases expression	ISO	RGD:68566	6480464	rofecoxib results in decreased expression of EPHA3 mRNA	CTD	PMID:17070997
Epha3	Mouse	rotenone	increases expression	ISO	RGD:68566	6480464	Rotenone results in increased expression of EPHA3 mRNA	CTD	PMID:36586010
Epha3	Mouse	S-(1,2-dichlorovinyl)-L-cysteine	decreases expression	ISO	RGD:68566	6480464	S-(1,2-dichlorovinyl)cysteine results in decreased expression of EPHA3 mRNA	CTD	PMID:35811015
Epha3	Mouse	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	RGD:68566	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of EPHA3 mRNA; [S-(1,2-dichlorovinyl)cysteine more ...	CTD	PMID:35811015
Epha3	Mouse	SB 431542	multiple interactions	ISO	RGD:68566	6480464	[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ...	CTD	PMID:27188386
Epha3	Mouse	silicon dioxide	decreases expression	ISO	RGD:68389	6480464	Silicon Dioxide results in decreased expression of EPHA3 mRNA	CTD	PMID:32721576
Epha3	Mouse	silver atom	decreases expression	EXP		6480464	Silver results in decreased expression of EPHA3 mRNA	CTD	PMID:27131904
Epha3	Mouse	silver(0)	decreases expression	EXP		6480464	Silver results in decreased expression of EPHA3 mRNA	CTD	PMID:27131904
Epha3	Mouse	simvastatin	multiple interactions	ISO	RGD:68566	6480464	[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated more ...	CTD	PMID:28263720
Epha3	Mouse	sotorasib	multiple interactions	ISO	RGD:68566	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA3 mRNA	CTD	PMID:36139627
Epha3	Mouse	sunitinib	increases expression	ISO	RGD:68566	6480464	Sunitinib results in increased expression of EPHA3 mRNA	CTD	PMID:31533062
Epha3	Mouse	temozolomide	increases expression	ISO	RGD:68566	6480464	Temozolomide results in increased expression of EPHA3 mRNA	CTD	PMID:31758290
Epha3	Mouse	tetrachloroethene	increases expression	EXP		6480464	Tetrachloroethylene results in increased expression of EPHA3 mRNA	CTD	PMID:28973375
Epha3	Mouse	tetrachloromethane	affects expression	EXP		6480464	Carbon Tetrachloride affects the expression of EPHA3 mRNA	CTD	PMID:17484886
Epha3	Mouse	titanium dioxide	decreases methylation	EXP		6480464	titanium dioxide results in decreased methylation of EPHA3 gene	CTD	PMID:35295148
Epha3	Mouse	trametinib	multiple interactions	ISO	RGD:68566	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPHA3 mRNA	CTD	PMID:36139627
Epha3	Mouse	trichostatin A	decreases expression	ISO	RGD:68566	6480464	trichostatin A results in decreased expression of EPHA3 mRNA	CTD	PMID:24935251\|PMID:26272509\|PMID:26705709
Epha3	Mouse	trichostatin A	multiple interactions	ISO	RGD:68566	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Epha3	Mouse	triclosan	increases expression	ISO	RGD:68566	6480464	Triclosan results in increased expression of EPHA3 mRNA	CTD	PMID:30510588
Epha3	Mouse	valproic acid	affects expression	EXP		6480464	Valproic Acid affects the expression of EPHA3 mRNA	CTD	PMID:17292431
Epha3	Mouse	valproic acid	decreases expression	ISO	RGD:68566	6480464	Valproic Acid results in decreased expression of EPHA3 mRNA	CTD	PMID:23179753\|PMID:27188386
Epha3	Mouse	valproic acid	increases expression	ISO	RGD:68566	6480464	Valproic Acid results in increased expression of EPHA3 mRNA	CTD	PMID:23179753\|PMID:24935251\|PMID:28001369
Epha3	Mouse	XL147	multiple interactions	EXP		6480464	[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPHA3 mRNA	CTD	PMID:27935865

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	axon guidance	involved_in	IBA	PANTHER:PTN000699977\|MGI:1096337\|MGI:99611\|MGI:104770\|MGI:95276\|MGI:109378\|MGI:98277	2290270		GO_Central	GO_REF:0000033
Epha3	Mouse	brain-derived neurotrophic factor receptor signaling pathway	involved_in	IEA	GO:0060175	2290270		GOC	GO_REF:0000108
Epha3	Mouse	cell migration	involved_in	IMP		2290270	PMID:17046737	UniProt	PMID:17046737
Epha3	Mouse	cellular response to follicle-stimulating hormone stimulus	acts_upstream_of_or_within	IDA		2290270	PMID:23242526	MGI	PMID:23242526
Epha3	Mouse	cellular response to interleukin-1		ISO	RGD:68389	9068941		RGD	PMID:9458884\|REF_RGD_ID:68243
Epha3	Mouse	cellular response to retinoic acid	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	collagen-activated tyrosine kinase receptor signaling pathway	involved_in	IEA	GO:0038062	2290270		GOC	GO_REF:0000108
Epha3	Mouse	endocardial cushion development	involved_in	IMP		2290270	PMID:17046737	UniProt	PMID:17046737
Epha3	Mouse	ephrin receptor signaling pathway	involved_in	IDA		2290270	PMID:21135139	UniProt	PMID:21135139
Epha3	Mouse	ephrin receptor signaling pathway	involved_in	IBA	PANTHER:PTN000699977\|MGI:99611\|UniProtKB:Q15375\|MGI:99612\|UniProtKB:P29320\|UniProtKB:P54762\|UniProtKB:P54764\|MGI:1096337\|MGI:95276\|UniProtKB:P54753\|RGD:620831\|UniProtKB:A0A8M1QKD8\|MGI:109378	2290270		GO_Central	GO_REF:0000033
Epha3	Mouse	ephrin receptor signaling pathway	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	epidermal growth factor receptor signaling pathway	involved_in	IEA	GO:0005006	2290270		GOC	GO_REF:0000108
Epha3	Mouse	fasciculation of motor neuron axon	involved_in	IMP		2290270	PMID:18403711	UniProt	PMID:18403711
Epha3	Mouse	fasciculation of sensory neuron axon	involved_in	IMP		2290270	PMID:21791286	UniProt	PMID:21791286
Epha3	Mouse	fever generation		ISO	RGD:68389	9068941		RGD	PMID:15671251\|REF_RGD_ID:1581943
Epha3	Mouse	fibroblast growth factor receptor signaling pathway	involved_in	IEA	GO:0005007	2290270		GOC	GO_REF:0000108
Epha3	Mouse	hepatocyte growth factor receptor signaling pathway	involved_in	IEA	GO:0005008	2290270		GOC	GO_REF:0000108
Epha3	Mouse	insulin receptor signaling pathway	involved_in	IEA	GO:0005009	2290270		GOC	GO_REF:0000108
Epha3	Mouse	insulin-like growth factor receptor signaling pathway	involved_in	IEA	GO:0005010	2290270		GOC	GO_REF:0000108
Epha3	Mouse	Kit signaling pathway	involved_in	IEA	GO:0005020	2290270		GOC	GO_REF:0000108
Epha3	Mouse	macrophage colony-stimulating factor signaling pathway	involved_in	IEA	GO:0005011	2290270		GOC	GO_REF:0000108
Epha3	Mouse	motor neuron axon guidance	NOT\|involved_in	IMP		2290270	PMID:17046737	UniProt	PMID:17046737
Epha3	Mouse	negative regulation of endocytosis	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	negative regulation of neuron projection development	acts_upstream_of_or_within	IDA		2290270	PMID:19505147	MGI	PMID:19505147
Epha3	Mouse	peptidyl-tyrosine phosphorylation	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	platelet-derived growth factor receptor-alpha signaling pathway	involved_in	IEA	GO:0005018	2290270		GOC	GO_REF:0000108
Epha3	Mouse	platelet-derived growth factor receptor-beta signaling pathway	involved_in	IEA	GO:0005019	2290270		GOC	GO_REF:0000108
Epha3	Mouse	positive regulation of neuron projection development	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	positive regulation of protein localization to plasma membrane	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	regulation of actin cytoskeleton organization	involved_in	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	regulation of actin cytoskeleton organization	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	regulation of cell migration	acts_upstream_of_or_within	IGI	MGI:109601	2290270	PMID:19505147	MGI	PMID:19505147
Epha3	Mouse	regulation of epithelial to mesenchymal transition	involved_in	IMP		2290270	PMID:17046737	UniProt	PMID:17046737
Epha3	Mouse	regulation of focal adhesion assembly	involved_in	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	regulation of focal adhesion assembly	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	regulation of microtubule cytoskeleton organization	involved_in	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	regulation of microtubule cytoskeleton organization	involved_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	response to lipopolysaccharide		ISO	RGD:68389	9068941		RGD	PMID:15671251\|REF_RGD_ID:1581943
Epha3	Mouse	synaptic membrane adhesion	involved_in	IDA		2290270	PMID:22275477	SynGO	PMID:22275477
Epha3	Mouse	synaptic membrane adhesion	involved_in	IMP		2290270	PMID:22275477	SynGO	PMID:22275477
Epha3	Mouse	vascular endothelial growth factor receptor-1 signaling pathway	involved_in	IEA	GO:0036332	2290270		GOC	GO_REF:0000108
Epha3	Mouse	vascular endothelial growth factor signaling pathway	involved_in	IEA	GO:0005021	2290270		GOC	GO_REF:0000108

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	actin cytoskeleton	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	cytosol	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	dendrite	is_active_in	IBA	PANTHER:PTN000699977\|RGD:1564232\|MGI:98277\|UniProtKB:P54756\|RGD:1560587\|RGD:70957\|MGI:99611	2290270		GO_Central	GO_REF:0000033
Epha3	Mouse	early endosome	located_in	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	early endosome	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	2290270		UniProt	GO_REF:0000044
Epha3	Mouse	GABA-ergic synapse	is_active_in	IDA		2290270	PMID:22275477	SynGO	PMID:22275477
Epha3	Mouse	GABA-ergic synapse	is_active_in	IMP		2290270	PMID:22275477	SynGO	PMID:22275477
Epha3	Mouse	nuclear membrane	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	nucleoplasm	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	plasma membrane	is_active_in	IBA	PANTHER:PTN001230543\|MGI:109378\|UniProtKB:P54762\|UniProtKB:P29323\|MGI:98277\|RGD:620831\|UniProtKB:P29320\|UniProtKB:P54756\|UniProtKB:Q15375\|RGD:1560587\|UniProtKB:P54753\|RGD:70957\|MGI:99611	2290270		GO_Central	GO_REF:0000033
Epha3	Mouse	plasma membrane	located_in	TAS		2290270		Reactome	Reactome:R-MMU-3928661
Epha3	Mouse	plasma membrane	located_in	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	plasma membrane	located_in	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	presynapse	is_active_in	IDA		2290270	PMID:22275477	SynGO	PMID:22275477

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	2290270		UniProt	GO_REF:0000043
Epha3	Mouse	boss receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	brain-derived neurotrophic factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	ephrin receptor activity	enables	IDA		2290270	PMID:15145949	MGI	PMID:15145949
Epha3	Mouse	ephrin receptor activity	enables	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	epidermal growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	fibroblast growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	GPI-linked ephrin receptor activity	enables	ISO	UniProtKB:P29320	2290270		GO_Central	GO_REF:0000119
Epha3	Mouse	GPI-linked ephrin receptor activity	enables	ISS	UniProtKB:P29320	2290270		UniProt	GO_REF:0000024
Epha3	Mouse	growth factor binding	enables	IPI	UniProtKB:P52797\|UniProtKB:P52801	2290270	PMID:22568954	ARUK-UCL	PMID:22568954
Epha3	Mouse	hepatocyte growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	insulin receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	insulin-like growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	macrophage colony-stimulating factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	placental growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	platelet-derived growth factor alpha-receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	platelet-derived growth factor beta-receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	protein binding	enables	IPI	PR:Q99M51	2290270	PMID:19505147	MGI	PMID:19505147
Epha3	Mouse	protein tyrosine kinase collagen receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	stem cell factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	transmembrane-ephrin receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003
Epha3	Mouse	transmembrane-ephrin receptor activity	enables	IBA	PANTHER:PTN000699977\|UniProtKB:P54762\|MGI:99611\|UniProtKB:Q5JZY3\|MGI:98277	2290270		GO_Central	GO_REF:0000033
Epha3	Mouse	vascular endothelial growth factor receptor activity	enables	IEA	EC:2.7.10.1	2290270		UniProt	GO_REF:0000003

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	ephrin - ephrin receptor bidirectional signaling axis		ISO	RGD:68566	6484113		PID	PID:200142

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Epha3	Mouse	abnormal atrioventricular cushion morphology		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal atrioventricular septum morphology		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal behavior		IEA		5509061		MGI
Epha3	Mouse	abnormal cardiac epithelial to mesenchymal transition		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal cardiovascular system physiology		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal heart development		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal kidney morphology		IEA		5509061		MGI
Epha3	Mouse	abnormal liver morphology		IEA		5509061		MGI
Epha3	Mouse	abnormal lung morphology		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	abnormal spleen morphology		IEA		5509061		MGI
Epha3	Mouse	atrioventricular block		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	atrioventricular cushion hypoplasia		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	atrioventricular valve regurgitation		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	congestive heart failure		IAGP		5509061		MGI	PMID:14585969
Epha3	Mouse	congestive heart failure		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	cyanosis		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	decreased anxiety-related response		IEA		5509061		MGI
Epha3	Mouse	decreased body length		IEA		5509061		MGI
Epha3	Mouse	decreased heart rate		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	decreased thigmotaxis		IEA		5509061		MGI
Epha3	Mouse	dilated heart atrium		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	enlarged kidney		IEA		5509061		MGI
Epha3	Mouse	hyperactivity		IEA		5509061		MGI
Epha3	Mouse	lethargy		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	liver vascular congestion		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	ostium primum atrial septal defect		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	perinatal lethality, incomplete penetrance		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	perinatal lethality, incomplete penetrance		IAGP		5509061		MGI	PMID:14585969
Epha3	Mouse	prolonged PR interval		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	pulmonary alveolar hemorrhage		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	pulmonary edema		IAGP		5509061		MGI	PMID:14585969
Epha3	Mouse	pulmonary vascular congestion		IAGP		5509061		MGI	PMID:17046737
Epha3	Mouse	small liver		IEA		5509061		MGI
Epha3	Mouse	small spleen		IEA		5509061		MGI
Epha3	Mouse	venoocclusion		IAGP		5509061		MGI	PMID:17046737

#	Reference Title	Reference Citation
1.	Zic2 controls cerebellar development in cooperation with Zic1.	Aruga J, etal., J Neurosci 2002 Jan 1;22(1):218-25.
2.	Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors.	Cheng N, etal., Neoplasia. 2003 Sep-Oct;5(5):445-56.
3.	Upregulation of EphA3 receptor after spinal cord injury.	Irizarry-Ramirez M, etal., J Neurotrauma. 2005 Aug;22(8):929-35.
4.	Expression of Eph receptors and their ligands, ephrins, during lipopolysaccharide fever in rats.	Ivanov AI, etal., Physiol Genomics. 2005 Apr 14;21(2):152-60. Epub 2005 Jan 25.
5.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
6.	MGDs mouse GO annotations	MGD data from the GO Consortium
7.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:1281307	PMID:1657122	PMID:2025425	PMID:7522971	PMID:8108111	PMID:8552593	PMID:8812059	PMID:8889548	PMID:9267020	PMID:9883724	PMID:10349636	PMID:10495276
PMID:10559410	PMID:10929715	PMID:11042159	PMID:11076861	PMID:11114734	PMID:11217851	PMID:11222144	PMID:11403717	PMID:11439183	PMID:11493561	PMID:11748150	PMID:11793228
PMID:12124402	PMID:12217323	PMID:12477932	PMID:12528186	PMID:12684176	PMID:12895420	PMID:12971893	PMID:14585969	PMID:14681479	PMID:15142957	PMID:15145949	PMID:15254900
PMID:15258590	PMID:15517401	PMID:15778706	PMID:15788771	PMID:15820684	PMID:15892098	PMID:15944189	PMID:15996548	PMID:16079153	PMID:16107646	PMID:16141072	PMID:16141073
PMID:16185771	PMID:16380715	PMID:16446123	PMID:16491080	PMID:16547242	PMID:16602821	PMID:16774998	PMID:16829211	PMID:16910173	PMID:17039519	PMID:17046737	PMID:17145500
PMID:17698011	PMID:18287559	PMID:18403711	PMID:19168674	PMID:19247962	PMID:19505147	PMID:19542359	PMID:19576892	PMID:19769959	PMID:19914184	PMID:20112066	PMID:20436479
PMID:20473036	PMID:20576928	PMID:20655977	PMID:21135139	PMID:21150899	PMID:21267068	PMID:21465626	PMID:21791286	PMID:21862448	PMID:21873635	PMID:21966449	PMID:22103416
PMID:22171039	PMID:22275477	PMID:22465667	PMID:22568954	PMID:22627288	PMID:22811059	PMID:23242526	PMID:23615279	PMID:23749471	PMID:23892084	PMID:24038871	PMID:24117969
PMID:24427155	PMID:24723342	PMID:24728844	PMID:24803655	PMID:24952961	PMID:25073978	PMID:25367067	PMID:25480914	PMID:25713296	PMID:25859222	PMID:26238476	PMID:26297811
PMID:26644518	PMID:26830346	PMID:26874185	PMID:26941654	PMID:27046536	PMID:27518902	PMID:27568519	PMID:27803162	PMID:27889898	PMID:28169277	PMID:28197551	PMID:28378742
PMID:28538179	PMID:28558017	PMID:29878134	PMID:31001083	PMID:31262977	PMID:31351040	PMID:31577226	PMID:31597102	PMID:32553152	PMID:32857879	PMID:33554859	PMID:34321999
PMID:34732824	PMID:35974052	PMID:36028553	PMID:36369193	PMID:36529279	PMID:36734036	PMID:37869988	PMID:38086370	PMID:38355793	PMID:39348458

Epha3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	63,363,895 - 63,684,538 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	63,363,897 - 63,684,538 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	63,543,532 - 63,864,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	63,543,534 - 63,864,175 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	63,545,044 - 63,863,983 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	63,487,420 - 63,806,359 (-)	NCBI		MGSCv36	mm8
Celera	16	63,844,890 - 64,154,791 (-)	NCBI		Celera
Cytogenetic Map	16	C1.3	NCBI
cM Map	16	36.49	NCBI

EPHA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	89,107,621 - 89,482,134 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	89,107,621 - 89,482,134 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	89,156,771 - 89,531,284 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	89,239,364 - 89,613,974 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	89,239,501 - 89,532,185	NCBI
Celera	3	89,910,744 - 90,285,017 (+)	NCBI		Celera
Cytogenetic Map	3	p11.1	NCBI
HuRef	3	89,169,906 - 89,544,877 (+)	NCBI		HuRef
CHM1_1	3	89,109,505 - 89,484,203 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	89,183,660 - 89,558,507 (+)	NCBI		T2T-CHM13v2.0

Epha3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	14,585,041 - 14,920,721 (-)	NCBI		GRCr8
mRatBN7.2	11	1,138,485 - 1,474,102 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	1,140,985 - 1,473,900 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	9,737,055 - 10,069,925 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	2,530,362 - 2,863,260 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	1,635,123 - 1,968,001 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	421,253 - 783,037 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	421,135 - 782,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	696,185 - 1,033,287 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	696,200 - 1,033,287 (-)	NCBI
Celera	11	1,134,161 - 1,466,533 (-)	NCBI		Celera
Cytogenetic Map	11	p12	NCBI

Epha3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	4,138,362 - 4,500,688 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	4,135,671 - 4,500,900 (-)	NCBI	ChiLan1.0	ChiLan1.0

EPHA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	89,283,121 - 89,651,438 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	89,287,895 - 89,656,226 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	89,261,166 - 89,629,010 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	91,369,233 - 91,737,300 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	91,369,239 - 91,739,056 (+)	Ensembl	panpan1.1		panPan2

EPHA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	770,234 - 1,092,063 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	769,423 - 1,115,986 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	949,355 - 1,298,894 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	810,080 - 1,159,494 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	810,033 - 1,149,524 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	779,847 - 1,129,604 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	811,416 - 1,161,165 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	1,284,819 - 1,381,967 (+)	NCBI		UU_Cfam_GSD_1.0

Epha3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	462,842 - 799,414 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936610	462,853 - 799,364 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936610	462,842 - 799,466 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPHA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	166,592,493 - 166,942,767 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	166,592,492 - 166,942,791 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	177,406,602 - 177,539,843 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	13	177,670,369 - 177,810,115 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPHA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	87,480,220 - 87,840,628 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	87,480,126 - 87,838,512 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	78,860,955 - 79,218,698 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Epha3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624789	5,534,121 - 5,922,861 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624789	5,534,011 - 5,925,592 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Epha3
11648 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	896
Count of miRNA genes:	486
Interacting mature miRNAs:	633
Transcripts:	ENSMUST00000064405
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1301138	Pcd4ts3_m	p-glycoprotein positive CD4 T cell subset 3 (mouse)			Not determined		16	40593923	74594076	Mouse
1301394	Eae11_m	susceptibility to experimental allergic encephalomyelitis 11 (mouse)			Not determined		16	53561891	87562035	Mouse
26884376	Skwq4_m	skull length QTL 4, 5 week (mouse)					16	8417864	90896888	Mouse
1302096	Aod1a_m	autoimmune ovarian dysgenesis 1a (mouse)			Not determined		16	35446643	92573008	Mouse
4141212	Imraq3_m	immune response to AAV2 QTL 3 (mouse)			Not determined		16	44383350	78383506	Mouse
1558836	Dice1b_m	determination of interleukin 4 commitment 1b (mouse)			Not determined		16	45511000	72274485	Mouse
1558740	Bpq9_m	blood pressure QTL 9 (mouse)			Not determined		16	63327336	97327472	Mouse
1301719	Remslp3_m	rapid eye movement sleep 3 (mouse)			Not determined		16	44383350	78383506	Mouse
1357778	Diobq_m	diet-induced obesity QTL (mouse)			Not determined		16	42197817	82331174	Mouse
4141113	Tgq28_m	triglyceride QTL 28 (mouse)			Not determined			62986646	96986646	Mouse
1301364	Lith14_m	lithogenic gene 14 (mouse)			Not determined		16	55661846	89661961	Mouse
26884432	Zlq7_m	zygomatic length QTL 7, 10 week (mouse)					16	3817864	64620363	Mouse
1300928	Etia_m	ethanol induced activation (mouse)			Not determined		16	63313907	97314016	Mouse
4142187	Arrd3_m	age-related retinal degeneration 3 (mouse)			Not determined			32522909	65466552	Mouse
11522747	Eae41_m	experimental allergic encephalomyelitis susceptibility 41 (mouse)					16	40399134	78015472	Mouse
14928310	Manh80_m	mandible shape 80 (mouse)					16	48219841	82219841	Mouse
1301125	Sluc27_m	susceptibility to lung cancer 27 (mouse)			Not determined		16	61608644	95608764	Mouse
1357763	Lp1_m	lymphocyte proliferation 1 (mouse)			Not determined		16	6542979	65466552	Mouse
1357517	Bwtn1_m	body weight at necropsy 1 (mouse)			Not determined		16	20019329	85600826	Mouse
26884416	Bzwq5_m	bi-zygomatic width QTL 5, 5 week (mouse)					16	37320362	84696888	Mouse
1301070	Cypr1_m	cytokine production 1 (mouse)			Not determined		16	32312795	66312933	Mouse
27226785	Feml12_m	femur length 12, 5 week (mouse)					16	3317864	64620363	Mouse
4142112	Skts-fp3_m	skin tumor susceptibility in FVB and PWK 3 (mouse)			Not determined		16	40053881	72924385	Mouse

AW492086

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,603,529 - 63,603,622	UniSTS	GRCm38
MGSCv37	16	63,603,355 - 63,603,448	UniSTS	GRCm37
Celera	16	63,902,969 - 63,903,062	UniSTS
Cytogenetic Map	16	C1.3	UniSTS
Whitehead/MRC_RH	16	704.16	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	16	63,566,410 - 63,566,476	UniSTS	GRCm37
MGSCv37	16	63,863,882 - 63,863,945	UniSTS	GRCm37
MGSCv37	16	63,545,830 - 63,545,975	UniSTS	GRCm37
Celera	16	63,845,676 - 63,845,821	UniSTS
Celera	16	63,866,112 - 63,866,178	UniSTS
Celera	16	64,154,690 - 64,154,753	UniSTS
Cytogenetic Map	16	C1.3	UniSTS
cM Map	16		UniSTS

M68513

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,545,997 - 63,546,131	UniSTS	GRCm38
MGSCv37	16	63,545,823 - 63,545,957	UniSTS	GRCm37
Celera	16	63,845,669 - 63,845,803	UniSTS
Cytogenetic Map	16	C1.3	UniSTS
Whitehead/MRC_RH	16	706.12	UniSTS

UniSTS:224333

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,610,631 - 63,610,786	UniSTS	GRCm38
MGSCv37	16	63,610,457 - 63,610,612	UniSTS	GRCm37
Celera	16	63,910,067 - 63,910,222	UniSTS
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,566,584 - 63,566,650	UniSTS	GRCm38
MGSCv37	16	63,566,410 - 63,566,476	UniSTS	GRCm37
Celera	16	63,866,112 - 63,866,178	UniSTS
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,864,056 - 63,864,119	UniSTS	GRCm38
MGSCv37	16	63,863,882 - 63,863,945	UniSTS	GRCm37
Celera	16	64,154,690 - 64,154,753	UniSTS
Cytogenetic Map	16	C1.3	UniSTS

Epha3

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	16	63,546,004 - 63,546,149	UniSTS	GRCm38
MGSCv37	16	63,545,830 - 63,545,975	UniSTS	GRCm37
Celera	16	63,845,676 - 63,845,821	UniSTS
Cytogenetic Map	16	C1.3	UniSTS
cM Map	16		UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_001362452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_010140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC154568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC154844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC155275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK041935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK044936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK045219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK084921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK089119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK132335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW491216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC053479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC060164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC093483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC138641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC138643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC145349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M68513	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M68515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000064405 ⟹ ENSMUSP00000066554

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,363,897 - 63,684,521 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,543,534 - 63,864,158 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000231270 ⟹ ENSMUSP00000156331

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,593,564 - 63,684,499 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,773,201 - 63,864,136 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000232049 ⟹ ENSMUSP00000155946

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,366,468 - 63,684,443 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,546,105 - 63,864,080 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000232370

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,662,281 - 63,684,538 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,841,918 - 63,864,175 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000232461 ⟹ ENSMUSP00000155890

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,431,386 - 63,683,776 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,611,023 - 63,863,413 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000232654 ⟹ ENSMUSP00000155997

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	16	63,430,675 - 63,684,520 (-)	Ensembl
GRCm38.p6 Ensembl	16	63,610,312 - 63,864,157 (-)	Ensembl

RefSeq Acc Id:

NM_001362452 ⟹ NP_001349381

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	16	63,363,895 - 63,684,538 (-)	NCBI
GRCm38	16	63,543,532 - 63,864,175 (-)	NCBI

Sequence:

show sequence

AGTGTCAAACTTGACATCAGACTGCGAGCGGAGCATGGTAACTTCTCCAGCAATCAGAGCGCTCCCCCTCACATCAGTGGTATGCTTCGCGGAGATATGCTCCTCTCACTGCCCGGTGCACCAGCAAC
ATGGATTGTCACCTCTCCATCCTCGTCCTGCTCGGCTGCTGCGTCCTCAGCTGCTCCGGAGAACTGAGCCCACAGCCTTCCAACGAAGTTAATCTACTAGATTCGAAAACAATTCAAGGAGAGCTGGG
CTGGATCTCCTACCCATCCCATGGGTGGGAAGAGATCAGTGGTGTTGATGAACATTACACACCAATCAGGACTTACCAGGTGTGCAATGTCATGGATCACAGCCAAAATAATTGGCTGAGGACAAACT
GGGTACCCAGAAACTCAGCTCAGAAGATCTATGTGGAGCTAAAGTTCACACTGCGGGACTGTAACAGCATTCCATTGGTTTTGGGGACTTGCAAGGAGACCTTTAACCTGTACTACATGGAGTCTGAT
GATGATCATGGCGTCAAATTCCGAGAGCATCAGTTCACGAAGATTGACACCATTGCCGCTGATGAAAGTTTCACTCAGATGGATCTCGGGGATCGCATTCTGAAACTCAACACTGAGATTAGAGAAGT
GGGACCAGTCAACAAAAAGGGGTTTTATTTGGCCTTTCAAGATGTTGGTGCTTGTGTTGCCTTGGTGTCTGTGAGAGTGTACTTCAAAAAGTGCCCGTTTACAGTGAAGAATCTGGCTATGTTTCCAG
ACACAGTGCCCATGGACTCCCAGTCTTTGGTGGAGGTTAGGGGCTCTTGTGTCAATAATTCCAAAGAGGAGGACCCTCCCAGGATGTACTGCAGCACAGAAGGGGAATGGCTGGTCCCCATTGGCAAA
TGCACTTGCAATGCTGGGTATGAAGAACGAGGTTTCATATGCCAAGCTTGTCGACCAGGCTTCTACAAGGCTTCCGATGGTGCTGCTAAGTGTGCTAAGTGCCCACCACACAGCTCAACACAAGAAGA
TGGTTCAATGAACTGCAGGTGTGAGAATAATTATTTCCGGGCAGAAAAAGACCCTCCATCCATGGCTTGTACCCGACCTCCATCCGCACCAAGAAATGTTATCTCAAACATAAACGAGACCTCGGTTA
TCCTGGACTGGAGTTGGCCCCTGGACACAGGAGGCCGGAAGGATATTACCTTCAACATCATATGTAAAAAGTGTGGGTGGAATGTCAGGCAGTGTGAGCCGTGCAGCCCCAACGTCCGCTTCCTTCCT
CGGCAGCTTGGACTCACCAACACCACGGTGACAGTGACAGACCTCCTAGCTCACACCAACTACACCTTTGAGATCGATGCTGTTAATGGGGTGTCAGAGCTGAGCTCGCCACCGAGACAGTATGCCGC
AGTCAGCATCACAACTAATCAGGCTGCTCCATCACCAGTTATGACAATTAAGAAAGATCGGACTTCCAGAAACAGTATCTCTTTATCTTGGCAAGAACCGGAACATCCAAATGGAATTATCCTGGACT
ATGAGGTCAAATACTATGAAAAGGAGCAAGAGACGAGTTATACCATTTTGAGAGCAAGAGGCACAAATGTTACTATCAGTAGCCTCAAGCCAGATACTACTTATGTCTTCCAAATCCGAGCTCGGACA
GCAGCGGGATATGGAACCAACAGCCGCAAATTTGAATTTGAAACTAGCCCAGACTCTTTCTCCATCTCCGGTGAAAACAGTCATGTGGTGATGATTGCTATTTCCGCAGCTGTGGCCATCATTGTCCT
CACGGTGGTCACCTATGTTCTGGTCGGGAGGTTTTGTGGCTATCACAAGTCAAAACACAGTGCAGAGGAGAAGCGCCTTCACTTTGGGAATGGCCACTTAAAACTTCCAGGTCTCAGGACCTATGTTG
ATCCACATACATATGAAGACCCTACTCAAGCAGTTCATGAGTTCGCGAAGGAGTTGGATGCCACCAATATATCCATCGACAAAGTTGTTGGAGCAGGTGAATTTGGAGAAGTTTGCAGCGGCCGCTTA
AAACTTCCTTCAAAAAAAGAGATTTCGGTGGCCATAAAGACCCTGAAAGTAGGGTATACCGAGAAACAGAGGAGAGACTTCCTCGGTGAAGCGAGCATCATGGGACAGTTTGACCATCCCAACATCAT
CCGACTGGAAGGCGTTGTCACTAAGAGTAAGCCAGTGATGATTGTCACGGAATACATGGAGAATGGCTCCTTGGACAGTTTCTTACGTAAGCACGATGCCCAGTTCACAGTCATCCAGCTTGTGGGAA
TGCTCCGTGGGATAGCATCAGGTATGAAATACCTCTCAGATATGGGCTACGTCCACCGGGACCTTGCTGCTCGCAACATCTTGATCAACAGTAACTTAGTGTGTAAAGTTTCTGACTTTGGACTCTCT
CGGGTACTTGAAGATGACCCAGAAGCTGCTTACACAACCAGGGGAGGAAAGATACCAATAAGGTGGACATCACCAGAAGCAATTGCCTACCGCAAGTTCACCTCAGCCAGCGATGTATGGAGTTACGG
GATTGTTCTCTGGGAAGTGATGTCTTACGGAGAAAGGCCATACTGGGAGATGTCCAATCAGGATGTAATTAAGGCTGTGGATGAGGGCTATCGCCTGCCACCTCCCATGGATTGCCCAGCTGCCTTGT
ATCAGTTGATGTTGGACTGCTGGCAGAAAGACAGGAACAACAGACCCAAGTTCGAGCAGATCGTCAGCATTCTGGACAAACTCATCCGGAATCCAGGCAGTCTGAAGATCATCACCAGCGCGGCTGCA
AGGCCATCAAACCTTCTTCTGGACCAAAGCAATGTCGATATCGCTACCTTCCACACAACTGGTGATTGGCTTAACGGCATGAGGACAGCACACTGTAAGGAAATCTTCACAGGCGTCGAATACAGCTC
CTGTGACACCATTGCCAAGATCTCCACAGATGACATGAAAAAGGTTGGTGTCACTGTGGTTGGGCCACAGAAGAAGATCATCAGCACCATTAAAGCTCTAGAAACACAATCTAAGAATGGTCCAGTTC
CAGTGTAAAGTCCTGGAGGGATGTGAGAAACGGGAAGATGCAGCAGCATCCTGCAGACAGATGGAAATGATAAATAAGATGCTGCAGAAAGCTCCAAGTCTAATAAGACACTCAGTTATAAGTCCAAA
TGCCTTAAAATGGAATTGAAAAATCTCTTTATTTTCCCCTATCATTTTACAGATGGGTGGGTGGGTGCATTTTGCTTTGTAATTGCTTTTTAAATGTTAATTGATGGGGTTAGTTAAAATTCTTCAGT
ATGAAGTGGAAGAACTAGTGTAGAGCCATTGATCATTAACTATCATGGAAATAAACCAAGTAAACTAGCAAAACAGACCTGAAGGCTTTGTTGTGAATGGCCACAGAGGAAAAGACTTGTCGTATTTT
TATACACAGAAAAAAATCTGTAACAGGTATTTTGTTTCTTTTAAAAACAAGCAAAATGGAGGCATTTATACCTCAAACTATCTGGCCATACTTACTACCTTATCACGTTAGTATTCTCTTTATCTGTT
TGAAGCATATAGAGATAAAGTTTGTAGTTGTTTTAAATACTATACATTTTTAATTGTTACCTTCCTTAAGTAGACCATGTAAAAACACGTCTTAATTTGGGGGCAAGTGCGTATTTATTTTCTTTTGG
ATTTTTAAATTGTTTTATATTTATGCCTTGATGATTTAATTTGGGTTTTGTTACAGCCAAGTGCCAAATGCTATTGCAAATTGTCAGCAGTAAGAAACATGTTTAACTATACCCAGAGAATTATATGT
TCTTTTCTACAACTGTTGAACAATCCACTTACATGTACCAACAAAATGAAATGCTTTCCCTGTTCCTACTGTCACCAAATCACTCACAGTCTGAATATCCCATTCATTTTTGTCTCTTCATTTATCAG
TAAATGTATGCTCCTAATTTAGTGTAATATACTGGCTTGTATGTAATAGATTTTTACCAAGATGTCATACCTTCCCTACTCTGGTGCTTAGAGGATATCAACTCCTTTCATTCATGAAAGAAGCTTGT
TAGAACTCCTTAGATTTGCAAACTGGAAAGATCAAAATGAGGTTAAATGGTTACAGTAATTGACAGCAGCATATAGGTAAATGCATGAGCCAAAAAAAAAAAAAATGATAAGAAAGAAAAATTGCTTG
TTTTGAAAAGTCTTAATATCATTGCTTAAACATGTAGAGAATGATGATAACTAAGCTACTCATCTGCATCACTGGGGTGTACGTCAATTAATTGCACACTTTCATGATCAATATCAGGTATAACTATC
TTTGAGTCTTCCACTTCAATGTACCTATTGTGAGTTAGGTGCATGATTAGAAGCCTTGGCCTTCTAAACATATTATTAAGCATAACATTTTTGAAAAAGCAACTCATCGAACCAATAAATCCACATCC
ACAGACAATGGAGGAATGAGATGTCTCATTATGGGGATGTAGTCTTGCTGTTCCGGAAAGGCCAATTGTAAGCATATTCTTGAATATTAAGAAGGATGTGCCTAACGGGCATCCTGATGATGACACAT
GCTGAAGCAATATTTTAGATTCTGGATTTTCTTGCTGATAGTATCATTCCATAGGATCAAGGGATGTGTGTGTCACAGAACAAGATGGTTCAAACAGTGCTGTACGAAATACGTCTCTATGCAAAAAG
GGACACTAAAGAAATACAGCTTCCAATCATAGAGGCAGATTTCCAAATGTAATCTGTTGTAGGTTTAGTATACTAGAGCTTAGGTGAGTTCTTTCAGATGTGAAATTGTTTCCCAAATGTTGACAATA
CTCCGTATCATGCTGCTAGAATTTGTACTGAACTTATAAGAGCATGAATATTTTGGAAATGAGCTGATGAAACTAATAATAAATTTTATATGTCCTGAAAGCAGGTAGAAAAGACTCTAATCAAGTAA
TTTAAAATTTGGAATACCAGGTCAAAATTCAAATCCAGCATCTGAACCAATTCGCCTATGACAGCATTGATTCTCTTAGGCAATATTCTGAACATGCTAAAAAAATGAATTTCAAAATAATTAGGTAT
TCAAAACTTGTTGAATCTGTTGCATTTATTTTGACTGAGAATTTTGTTTGAAATTAGAGGTGGTTTAAGCAGTATATTGCTTTTCATTTGTCAGTATTTTTCTATCTCACCGTTTATGGATTTCCTTT
GCATAACCCCTTCCCTGTACATATGTAAACATAACAGTGTACGATTCTGGACTGGGGAGTAGAGGTACTAGATCGCTTATGGCCATCTCTTTGTACAGGAACTACATTGCCTTCCCATATCAATGAGG
CTACCGCTCCCTTGCCATGTTATGTACCATATTACCTGATTTGTATCTTAAATTTGATTTATAGATATTATTTATTTCTCGCAACACACCCAGTCTAGGCTGTACTGAGTATCTATCAAGCCATGTAT
AAATATGATATGATTGGCAGTATGTGTTTACTTTAAACTTGCATTTTAAAAACATGGTTCATTTAGTTTATGTTGCACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTCTAGTGGGAACATTT
ATATTTTTATAATAAACATAATGAAAATATTTTTACAGATCAGAATAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_010140 ⟹ NP_034270

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	16	63,363,895 - 63,684,538 (-)	NCBI
GRCm38	16	63,543,532 - 63,864,175 (-)	NCBI
MGSCv37	16	63,545,044 - 63,863,983 (-)	RGD
Celera	16	63,844,890 - 64,154,791 (-)	RGD
cM Map	16		ENTREZGENE

Sequence:

show sequence

AGTGTCAAACTTGACATCAGACTGCGAGCGGAGCATGGTAACTTCTCCAGCAATCAGAGCGCTC
CCCCTCACATCAGTGGTATGCTTCGCGGAGATATGCTCCTCTCACTGCCCGGTGCACCAGCAACATGGATTGTCACCTCTCCATCCTCGTCCTGCTCGGCTGCTGCGTCCTCAGCTGCTCCGGAGAAC
TGAGCCCACAGCCTTCCAACGAAGTTAATCTACTAGATTCGAAAACAATTCAAGGAGAGCTGGGCTGGATCTCCTACCCATCCCATGGGTGGGAAGAGATCAGTGGTGTTGATGAACATTACACACCA
ATCAGGACTTACCAGGTGTGCAATGTCATGGATCACAGCCAAAATAATTGGCTGAGGACAAACTGGGTACCCAGAAACTCAGCTCAGAAGATCTATGTGGAGCTAAAGTTCACACTGCGGGACTGTAA
CAGCATTCCATTGGTTTTGGGGACTTGCAAGGAGACCTTTAACCTGTACTACATGGAGTCTGATGATGATCATGGCGTCAAATTCCGAGAGCATCAGTTCACGAAGATTGACACCATTGCCGCTGATG
AAAGTTTCACTCAGATGGATCTCGGGGATCGCATTCTGAAACTCAACACTGAGATTAGAGAAGTGGGACCAGTCAACAAAAAGGGGTTTTATTTGGCCTTTCAAGATGTTGGTGCTTGTGTTGCCTTG
GTGTCTGTGAGAGTGTACTTCAAAAAGTGCCCGTTTACAGTGAAGAATCTGGCTATGTTTCCAGACACAGTGCCCATGGACTCCCAGTCTTTGGTGGAGGTTAGGGGCTCTTGTGTCAATAATTCCAA
AGAGGAGGACCCTCCCAGGATGTACTGCAGCACAGAAGGGGAATGGCTGGTCCCCATTGGCAAATGCACTTGCAATGCTGGGTATGAAGAACGAGGTTTCATATGCCAAGCTTGTCGACCAGGCTTCT
ACAAGGCTTCCGATGGTGCTGCTAAGTGTGCTAAGTGCCCACCACACAGCTCAACACAAGAAGATGGTTCAATGAACTGCAGGTGTGAGAATAATTATTTCCGGGCAGAAAAAGACCCTCCATCCATG
GCTTGTACCCGACCTCCATCCGCACCAAGAAATGTTATCTCAAACATAAACGAGACCTCGGTTATCCTGGACTGGAGTTGGCCCCTGGACACAGGAGGCCGGAAGGATATTACCTTCAACATCATATG
TAAAAAGTGTGGGTGGAATGTCAGGCAGTGTGAGCCGTGCAGCCCCAACGTCCGCTTCCTTCCTCGGCAGCTTGGACTCACCAACACCACGGTGACAGTGACAGACCTCCTAGCTCACACCAACTACA
CCTTTGAGATCGATGCTGTTAATGGGGTGTCAGAGCTGAGCTCGCCACCGAGACAGTATGCCGCAGTCAGCATCACAACTAATCAGGCTGCTCCATCACCAGTTATGACAATTAAGAAAGATCGGACT
TCCAGAAACAGTATCTCTTTATCTTGGCAAGAACCGGAACATCCAAATGGAATTATCCTGGACTATGAGGTCAAATACTATGAAAAGCAGGAGCAAGAGACGAGTTATACCATTTTGAGAGCAAGAGG
CACAAATGTTACTATCAGTAGCCTCAAGCCAGATACTACTTATGTCTTCCAAATCCGAGCTCGGACAGCAGCGGGATATGGAACCAACAGCCGCAAATTTGAATTTGAAACTAGCCCAGACTCTTTCT
CCATCTCCGGTGAAAACAGTCATGTGGTGATGATTGCTATTTCCGCAGCTGTGGCCATCATTGTCCTCACGGTGGTCACCTATGTTCTGGTCGGGAGGTTTTGTGGCTATCACAAGTCAAAACACAGT
GCAGAGGAGAAGCGCCTTCACTTTGGGAATGGCCACTTAAAACTTCCAGGTCTCAGGACCTATGTTGATCCACATACATATGAAGACCCTACTCAAGCAGTTCATGAGTTCGCGAAGGAGTTGGATGC
CACCAATATATCCATCGACAAAGTTGTTGGAGCAGGTGAATTTGGAGAAGTTTGCAGCGGCCGCTTAAAACTTCCTTCAAAAAAAGAGATTTCGGTGGCCATAAAGACCCTGAAAGTAGGGTATACCG
AGAAACAGAGGAGAGACTTCCTCGGTGAAGCGAGCATCATGGGACAGTTTGACCATCCCAACATCATCCGACTGGAAGGCGTTGTCACTAAGAGTAAGCCAGTGATGATTGTCACGGAATACATGGAG
AATGGCTCCTTGGACAGTTTCTTACGTAAGCACGATGCCCAGTTCACAGTCATCCAGCTTGTGGGAATGCTCCGTGGGATAGCATCAGGTATGAAATACCTCTCAGATATGGGCTACGTCCACCGGGA
CCTTGCTGCTCGCAACATCTTGATCAACAGTAACTTAGTGTGTAAAGTTTCTGACTTTGGACTCTCTCGGGTACTTGAAGATGACCCAGAAGCTGCTTACACAACCAGGGGAGGAAAGATACCAATAA
GGTGGACATCACCAGAAGCAATTGCCTACCGCAAGTTCACCTCAGCCAGCGATGTATGGAGTTACGGGATTGTTCTCTGGGAAGTGATGTCTTACGGAGAAAGGCCATACTGGGAGATGTCCAATCAG
GATGTAATTAAGGCTGTGGATGAGGGCTATCGCCTGCCACCTCCCATGGATTGCCCAGCTGCCTTGTATCAGTTGATGTTGGACTGCTGGCAGAAAGACAGGAACAACAGACCCAAGTTCGAGCAGAT
CGTCAGCATTCTGGACAAACTCATCCGGAATCCAGGCAGTCTGAAGATCATCACCAGCGCGGCTGCAAGGCCATCAAACCTTCTTCTGGACCAAAGCAATGTCGATATCGCTACCTTCCACACAACTG
GTGATTGGCTTAACGGCATGAGGACAGCACACTGTAAGGAAATCTTCACAGGCGTCGAATACAGCTCCTGTGACACCATTGCCAAGATCTCCACAGATGACATGAAAAAGGTTGGTGTCACTGTGGTT
GGGCCACAGAAGAAGATCATCAGCACCATTAAAGCTCTAGAAACACAATCTAAGAATGGTCCAGTTCCAGTGTAAAGTCCTGGAGGGATGTGAGAAACGGGAAGATGCAGCAGCATCCTGCAGACAGA
TGGAAATGATAAATAAGATGCTGCAGAAAGCTCCAAGTCTAATAAGACACTCAGTTATAAGTCCAAATGCCTTAAAATGGAATTGAAAAATCTCTTTATTTTCCCCTATCATTTTACAGATGGGTGGG
TGGGTGCATTTTGCTTTGTAATTGCTTTTTAAATGTTAATTGATGGGGTTAGTTAAAATTCTTCAGTATGAAGTGGAAGAACTAGTGTAGAGCCATTGATCATTAACTATCATGGAAATAAACCAAGT
AAACTAGCAAAACAGACCTGAAGGCTTTGTTGTGAATGGCCACAGAGGAAAAGACTTGTCGTATTTTTATACACAGAAAAAAATCTGTAACAGGTATTTTGTTTCTTTTAAAAACAAGCAAAATGGAG
GCATTTATACCTCAAACTATCTGGCCATACTTACTACCTTATCACGTTAGTATTCTCTTTATCTGTTTGAAGCATATAGAGATAAAGTTTGTAGTTGTTTTAAATACTATACATTTTTAATTGTTACC
TTCCTTAAGTAGACCATGTAAAAACACGTCTTAATTTGGGGGCAAGTGCGTATTTATTTTCTTTTGGATTTTTAAATTGTTTTATATTTATGCCTTGATGATTTAATTTGGGTTTTGTTACAGCCAAG
TGCCAAATGCTATTGCAAATTGTCAGCAGTAAGAAACATGTTTAACTATACCCAGAGAATTATATGTTCTTTTCTACAACTGTTGAACAATCCACTTACATGTACCAACAAAATGAAATGCTTTCCCT
GTTCCTACTGTCACCAAATCACTCACAGTCTGAATATCCCATTCATTTTTGTCTCTTCATTTATCAGTAAATGTATGCTCCTAATTTAGTGTAATATACTGGCTTGTATGTAATAGATTTTTACCAAG
ATGTCATACCTTCCCTACTCTGGTGCTTAGAGGATATCAACTCCTTTCATTCATGAAAGAAGCTTGTTAGAACTCCTTAGATTTGCAAACTGGAAAGATCAAAATGAGGTTAAATGGTTACAGTAATT
GACAGCAGCATATAGGTAAATGCATGAGCCAAAAAAAAAAAAAATGATAAGAAAGAAAAATTGCTTGTTTTGAAAAGTCTTAATATCATTGCTTAAACATGTAGAGAATGATGATAACTAAGCTACTC
ATCTGCATCACTGGGGTGTACGTCAATTAATTGCACACTTTCATGATCAATATCAGGTATAACTATCTTTGAGTCTTCCACTTCAATGTACCTATTGTGAGTTAGGTGCATGATTAGAAGCCTTGGCC
TTCTAAACATATTATTAAGCATAACATTTTTGAAAAAGCAACTCATCGAACCAATAAATCCACATCCACAGACAATGGAGGAATGAGATGTCTCATTATGGGGATGTAGTCTTGCTGTTCCGGAAAGG
CCAATTGTAAGCATATTCTTGAATATTAAGAAGGATGTGCCTAACGGGCATCCTGATGATGACACATGCTGAAGCAATATTTTAGATTCTGGATTTTCTTGCTGATAGTATCATTCCATAGGATCAAG
GGATGTGTGTGTCACAGAACAAGATGGTTCAAACAGTGCTGTACGAAATACGTCTCTATGCAAAAAGGGACACTAAAGAAATACAGCTTCCAATCATAGAGGCAGATTTCCAAATGTAATCTGTTGTA
GGTTTAGTATACTAGAGCTTAGGTGAGTTCTTTCAGATGTGAAATTGTTTCCCAAATGTTGACAATACTCCGTATCATGCTGCTAGAATTTGTACTGAACTTATAAGAGCATGAATATTTTGGAAATG
AGCTGATGAAACTAATAATAAATTTTATATGTCCTGAAAGCAGGTAGAAAAGACTCTAATCAAGTAATTTAAAATTTGGAATACCAGGTCAAAATTCAAATCCAGCATCTGAACCAATTCGCCTATGA
CAGCATTGATTCTCTTAGGCAATATTCTGAACATGCTAAAAAAATGAATTTCAAAATAATTAGGTATTCAAAACTTGTTGAATCTGTTGCATTTATTTTGACTGAGAATTTTGTTTGAAATTAGAGGT
GGTTTAAGCAGTATATTGCTTTTCATTTGTCAGTATTTTTCTATCTCACCGTTTATGGATTTCCTTTGCATAACCCCTTCCCTGTACATATGTAAACATAACAGTGTACGATTCTGGACTGGGGAGTA
GAGGTACTAGATCGCTTATGGCCATCTCTTTGTACAGGAACTACATTGCCTTCCCATATCAATGAGGCTACCGCTCCCTTGCCATGTTATGTACCATATTACCTGATTTGTATCTTAAATTTGATTTA
TAGATATTATTTATTTCTCGCAACACACCCAGTCTAGGCTGTACTGAGTATCTATCAAGCCATGTATAAATATGATATGATTGGCAGTATGTGTTTACTTTAAACTTGCATTTTAAAAACATGGTTCA
TTTAGTTTATGTTGCACAATGTAGATGGCCTCTTACTAATGTAAAATGATTTCTAGTGGGAACATTTATATTTTTATAATAAACATAATGAAAATATTTTTACAGATCAGAATA

hide sequence


Protein RefSeqs	NP_001349381	(Get FASTA)	NCBI Sequence Viewer
	NP_034270	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA39521	(Get FASTA)	NCBI Sequence Viewer
	AAA39522	(Get FASTA)	NCBI Sequence Viewer
	AAI38642	(Get FASTA)	NCBI Sequence Viewer
	AAI38644	(Get FASTA)	NCBI Sequence Viewer
	AAI45350	(Get FASTA)	NCBI Sequence Viewer
	BAC31104	(Get FASTA)	NCBI Sequence Viewer
	BAC32266	(Get FASTA)	NCBI Sequence Viewer
	BAC39310	(Get FASTA)	NCBI Sequence Viewer
	BAE21112	(Get FASTA)	NCBI Sequence Viewer
	EDK98238	(Get FASTA)	NCBI Sequence Viewer
	EDK98239	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000066554
	ENSMUSP00000155946
GenBank Protein	P29319	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_034270 ⟸ NM_010140
- Peptide Label:	isoform 1 precursor
- UniProtKB:	Q8BRB1 (UniProtKB/TrEMBL), Q8C3U1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCHLSILVLLGCCVLSCSGELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESD DDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGK CTCNAGYEERGFICQACRPGFYKASDGAAKCAKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACTRPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLP RQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTTYVFQIRAR TAAGYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSAEEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGR LKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL SRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAA ARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISTIKALETQSKNGPVPV hide sequence

RefSeq Acc Id:	NP_001349381 ⟸ NM_001362452
- Peptide Label:	isoform 2 precursor
- UniProtKB:	B7ZNN5 (UniProtKB/TrEMBL), Q8C3U1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSMUSP00000156331 ⟸ ENSMUST00000231270

Ensembl Acc Id:

ENSMUSP00000155890 ⟸ ENSMUST00000232461

Ensembl Acc Id:

ENSMUSP00000155946 ⟸ ENSMUST00000232049

Protein Domains

Eph LBD Fibronectin type-III Protein kinase SAM

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P29319-F1-model_v2	AlphaFold	P29319	1-983	view protein structure

RGD ID:

6827023

Promoter ID:

MM_KWN:21372

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, MEF_B6

Transcripts:

ENSMUST00000064405, UC007ZPZ.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	16	63,863,686 - 63,864,186 (-)	MPROMDB

RGD ID:

13674214

Promoter ID:

EPDNEW_M21256

Type:

initiation region

Name:

Epha3_1

Description:

Mus musculus Eph receptor A3 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	16	63,864,175 - 63,864,235	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000052504	Ensembl, ENTREZGENE
Ensembl Transcript	ENSMUST00000064405	ENTREZGENE
	ENSMUST00000232049	ENTREZGENE
Gene3D-CATH	1.10.150.50	UniProtKB/Swiss-Prot
	2.60.40.10	UniProtKB/Swiss-Prot
	ephrin a2 ectodomain	UniProtKB/Swiss-Prot
	Galactose-binding domain-like	UniProtKB/Swiss-Prot
	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
	Tumor Necrosis Factor Receptor, subunit A, domain 2	UniProtKB/Swiss-Prot
InterPro	Eph_TM	UniProtKB/Swiss-Prot
	EphA3_rcpt_lig-bd	UniProtKB/Swiss-Prot
	Ephrin_rcpt_lig-bd_dom	UniProtKB/Swiss-Prot
	Ephrin_rcpt_TKs	UniProtKB/Swiss-Prot
	FN3_dom	UniProtKB/Swiss-Prot
	FN3_sf	UniProtKB/Swiss-Prot
	Galactose-bd-like_sf	UniProtKB/Swiss-Prot
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	SAM	UniProtKB/Swiss-Prot
	SAM/pointed_sf	UniProtKB/Swiss-Prot
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	Tyr-kin_ephrin_A/B_rcpt-like	UniProtKB/Swiss-Prot
	Tyr_kinase_AS	UniProtKB/Swiss-Prot
	Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	Tyr_kinase_ephrin_rcpt	UniProtKB/Swiss-Prot
	Tyr_kinase_rcpt_V_CS	UniProtKB/Swiss-Prot
MGD	MGI:99612	ENTREZGENE
NCBI Gene	13837	ENTREZGENE
PANTHER	EPH RECEPTOR A5	UniProtKB/Swiss-Prot
	EPHRIN TYPE-A RECEPTOR 3	UniProtKB/Swiss-Prot
Pfam	EphA2_TM	UniProtKB/Swiss-Prot
	Ephrin_lbd	UniProtKB/Swiss-Prot
	Ephrin_rec_like	UniProtKB/Swiss-Prot
	fn3	UniProtKB/Swiss-Prot
	Pkinase_Tyr	UniProtKB/Swiss-Prot
	SAM_2	UniProtKB/Swiss-Prot
PhenoGen	Epha3	PhenoGen
PIRSF	TyrPK_ephrin_receptor	UniProtKB/Swiss-Prot
PRINTS	FNTYPEIII	UniProtKB/Swiss-Prot
	TYRKINASE	UniProtKB/Swiss-Prot
PROSITE	EGF_2	UniProtKB/Swiss-Prot
	EPH_LBD	UniProtKB/Swiss-Prot
	FN3	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot
	RECEPTOR_TYR_KIN_V_1	UniProtKB/Swiss-Prot
	RECEPTOR_TYR_KIN_V_2	UniProtKB/Swiss-Prot
	SAM_DOMAIN	UniProtKB/Swiss-Prot
SMART	EPH_lbd	UniProtKB/Swiss-Prot
	Ephrin_rec_like	UniProtKB/Swiss-Prot
	FN3	UniProtKB/Swiss-Prot
	SAM	UniProtKB/Swiss-Prot
	TyrKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47769	UniProtKB/Swiss-Prot
	SSF49265	UniProtKB/Swiss-Prot
	SSF49785	UniProtKB/Swiss-Prot
	SSF56112	UniProtKB/Swiss-Prot
	SSF57184	UniProtKB/Swiss-Prot
UniProt	A0A338P6A7_MOUSE	UniProtKB/TrEMBL
	A0A338P7J9_MOUSE	UniProtKB/TrEMBL
	B7ZNN5	ENTREZGENE, UniProtKB/TrEMBL
	EPHA3_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8BRB1	ENTREZGENE, UniProtKB/TrEMBL
	Q8C3U1	ENTREZGENE, UniProtKB/TrEMBL
	Q8C9K6_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

Mammalian Phenotype

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

Mammalian Phenotype