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Gene: EPHB1 (EPH receptor B1) Homo sapiens
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Symbol: EPHB1
Name: EPH receptor B1
Description: Exhibits transmembrane-ephrin receptor activity. Involved in several processes, including ephrin receptor signaling pathway; protein autophosphorylation; and regulation of MAPK cascade. Localizes to several cellular components, including the early endosome membrane; endoplasmic reticulum; and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EK6; ELK; eph tyrosine kinase 2; EPH-like kinase 6; ephrin type-B receptor 1; EPHT2; FLJ37986; Hek6; NET; neuronally-expressed EPH-related tyrosine kinase; soluble EPHB1 variant 1; tyrosine-protein kinase receptor EPH-2
Orthologs:
Mus musculus (house mouse) : Ephb1 (Eph receptor B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ephb1 (Eph receptor B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephb1 (EPH receptor B1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHB1 (EPH receptor B1)
Canis lupus familiaris (dog) : EPHB1 (EPH receptor B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephb1 (EPH receptor B1)
Sus scrofa (pig) : EPHB1 (EPH receptor B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383134,595,264 - 135,260,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373134,514,099 - 134,979,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363135,996,950 - 136,461,999 (+)NCBINCBI36hg18NCBI36
Build 343135,996,957 - 136,462,003NCBI
Celera3132,940,535 - 133,405,242 (+)NCBI
Cytogenetic Map3q22.2NCBI
HuRef3131,890,822 - 132,356,715 (+)NCBIHuRef
CHM1_13134,478,274 - 134,942,745 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EPHB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353347
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.