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Gene: Ros1 (Ros1 proto-oncogene) Mus musculus
Symbol: Ros1
Name: Ros1 proto-oncogene
Description: Exhibits protein phosphatase binding activity. Involved in several processes, including protein phosphorylation; regulation of ERK1 and ERK2 cascade; and regulation of phosphate transport. Localizes to the cell surface and perinuclear region of cytoplasm. Is expressed in several structures, including genitourinary system; intestine; lung; stomach; and trunk. Orthologous to human ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase); INTERACTS WITH Aroclor 1254; benzo[b]fluoranthene; buta-1,3-diene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: c-ros; c-Ros receptor tyrosine kinase; c-ros-1; proto-oncogene c-Ros; proto-oncogene c-Ros-1; proto-oncogene tyrosine-protein kinase ROS; receptor tyrosine kinase c-ros oncogene 1; Ros-1
Homo sapiens (human) : ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ros1 (ROS proto-oncogene 1 , receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ros1 (ROS proto-oncogene 1, receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase)
Canis lupus familiaris (dog) : ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ros1 (ROS proto-oncogene 1, receptor tyrosine kinase)
Sus scrofa (pig) : ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381052,044,863 - 52,195,398 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371051,765,732 - 51,915,050 (-)NCBIGRCm37mm9NCBIm37
MGSCv361051,734,341 - 51,883,659 (-)NCBImm8
Celera1052,882,450 - 53,031,104 (-)NCBICelera
Cytogenetic Map10 B3NCBI
cM Map1026.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ros1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11244
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.