Nrp1 (neuropilin 1) - Rat Genome Database

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Gene: Nrp1 (neuropilin 1) Mus musculus
Analyze
Symbol: Nrp1
Name: neuropilin 1
RGD ID: 1552955
MGI Page MGI
Description: Enables protein kinase binding activity; transmembrane signaling receptor activity; and vascular endothelial growth factor binding activity. Involved in several processes, including cell surface receptor signaling pathway; nervous system development; and vasculature development. Acts upstream of or within several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and nervous system development. Located in several cellular components, including endosome; focal adhesion; and neurofilament. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in several structures, including cardiovascular system; jaw; lung; nervous system; and sensory organ. Used to study retinal vein occlusion. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and tetralogy of Fallot. Orthologous to human NRP1 (neuropilin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A5 protein; C530029I03; N; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP; NP-1; NPN-1; Npn1; Nrp; transmembrane receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398129,085,553 - 129,231,957 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8129,085,085 - 129,229,844 (+)EnsemblGRCm39 Ensembl
GRCm388128,358,591 - 128,505,476 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8128,358,604 - 128,503,363 (+)EnsemblGRCm38mm10GRCm38
MGSCv378130,882,973 - 131,029,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368131,228,923 - 131,389,437 (+)NCBIMGSCv36mm8
Celera8132,685,332 - 132,831,714 (+)NCBICelera
Cytogenetic Map8E2NCBI
cM Map875.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-Nitrobenzanthrone  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
8-Br-cAMP  (ISO)
acetaldehyde  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antimycin A  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
Azoxymethane  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
bisphenol AF  (ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
choline  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (ISO)
cytarabine  (EXP)
depsipeptide  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP,ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
disodium selenite  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
ethanol  (EXP,ISO)
fenthion  (EXP)
ferric oxide  (EXP)
flavonoids  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
graphite  (ISO)
hypochlorous acid  (EXP)
indoles  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
Morroniside  (ISO)
N-acetylsphingosine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
naproxen  (ISO)
nickel dichloride  (EXP)
nitrobenzenes  (ISO)
oxaliplatin  (ISO)
oxybenzone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PD 0325901  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
Ptaquiloside  (EXP)
quercetin  (ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
SB 431542  (ISO)
senecionine  (EXP)
serpentine asbestos  (ISO)
silicon dioxide  (EXP)
simvastatin  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sotorasib  (ISO)
sphingosine 1-phosphate  (ISO)
succimer  (EXP,ISO)
sulfadimethoxine  (ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (EXP,ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IGI,IMP,ISO)
angiogenesis involved in coronary vascular morphogenesis  (IMP)
artery morphogenesis  (IMP)
axon extension  (IGI)
axon extension involved in axon guidance  (IDA,IMP)
axon guidance  (IBA,IDA,IMP)
axonal fasciculation  (IMP)
axonogenesis involved in innervation  (IMP)
basal dendrite arborization  (IGI)
basal dendrite development  (IMP)
blood vessel endothelial cell migration  (IMP)
branching involved in blood vessel morphogenesis  (IMP)
branchiomotor neuron axon guidance  (IMP)
cardiac neural crest cell migration involved in outflow tract morphogenesis  (IMP)
cell migration involved in coronary vasculogenesis  (IC)
cell migration involved in sprouting angiogenesis  (IC,IMP)
cellular response to hepatocyte growth factor stimulus  (IEA,ISO)
cellular response to vascular endothelial growth factor stimulus  (IMP)
commissural neuron axon guidance  (IMP)
coronary artery morphogenesis  (IMP)
dendrite development  (IMP)
dichotomous subdivision of terminal units involved in salivary gland branching  (IGI,IMP)
dorsal root ganglion morphogenesis  (IMP)
endothelial cell chemotaxis  (IEA,ISO)
endothelial cell migration  (IMP)
facial nerve structural organization  (IMP)
facioacoustic ganglion development  (IMP)
gonadotrophin-releasing hormone neuronal migration to the hypothalamus  (IMP)
heart development  (IGI)
hepatocyte growth factor receptor signaling pathway  (IEA,ISO)
integrin-mediated signaling pathway  (IMP,ISO)
motor neuron axon guidance  (IMP)
motor neuron migration  (IMP)
negative regulation of axon extension  (IGI)
negative regulation of axon extension involved in axon guidance  (IDA,ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IMP)
negative regulation of neuron apoptotic process  (IMP)
neural crest cell migration  (IBA)
neural crest cell migration involved in autonomic nervous system development  (IMP)
neuron development  (IMP)
neuron migration  (IMP)
neuropilin signaling pathway  (IMP,ISO)
otic placode development  (IMP)
outflow tract septum morphogenesis  (IMP)
platelet-derived growth factor receptor signaling pathway  (IEA,ISO)
positive chemotaxis  (IMP)
positive regulation of angiogenesis  (IMP)
positive regulation of axon extension involved in axon guidance  (IMP)
positive regulation of cell migration involved in sprouting angiogenesis  (IMP)
positive regulation of endothelial cell migration  (IBA,IMP,ISO)
positive regulation of ERK1 and ERK2 cascade  (IMP)
positive regulation of filopodium assembly  (IBA,IMP,ISO)
positive regulation of focal adhesion assembly  (IEA,ISO)
positive regulation of phosphorylation  (IMP)
positive regulation of platelet-derived growth factor receptor signaling pathway  (IEA,ISO)
positive regulation of smooth muscle cell chemotaxis  (IEA,ISO)
positive regulation of stress fiber assembly  (IEA,ISO)
positive regulation of substrate adhesion-dependent cell spreading  (IEA,ISO)
positive regulation of vascular associated smooth muscle cell migration  (IEA,ISO)
postsynapse organization  (IDA,IMP)
protein localization to early endosome  (IMP)
regulation of axon extension involved in axon guidance  (IDA)
regulation of Cdc42 protein signal transduction  (IMP,ISO)
regulation of vascular endothelial growth factor receptor signaling pathway  (IBA)
renal artery morphogenesis  (IMP)
response to wounding  (IBA)
retina vasculature development in camera-type eye  (IMP)
retina vasculature morphogenesis in camera-type eye  (IMP)
retinal ganglion cell axon guidance  (IMP)
semaphorin-plexin signaling pathway  (IDA,IGI,IMP)
sensory neuron axon guidance  (IMP)
sprouting angiogenesis  (IBA,IMP)
substrate-dependent cell migration, cell extension  (IEA,ISO)
symbiont entry into host cell  (IEA,ISO)
sympathetic ganglion development  (IMP)
sympathetic nervous system development  (IMP)
sympathetic neuron projection extension  (IMP)
sympathetic neuron projection guidance  (IMP)
trigeminal ganglion development  (IMP)
trigeminal nerve morphogenesis  (IMP)
trigeminal nerve structural organization  (IMP)
vascular endothelial growth factor receptor signaling pathway  (IBA,IMP,ISO)
vasculogenesis  (IBA)
VEGF-activated neuropilin signaling pathway  (IMP,ISO)
ventral trunk neural crest cell migration  (IMP)
vestibulocochlear nerve structural organization  (IMP)
wound healing  (IEA,ISO)

Cellular Component
axon  (IBA,IDA,ISO)
cell surface  (IEA,ISO)
cytosol  (IEA,ISO)
early endosome  (IDA)
focal adhesion  (IBA,IDA,ISO)
glutamatergic synapse  (IDA,IMP)
growth cone  (IEA,ISO)
mitochondrial membrane  (IEA)
neurofilament  (IDA)
neuron projection  (IDA)
neuronal cell body  (IEA,ISO)
plasma membrane  (IBA,IDA,ISO,TAS)
postsynaptic membrane  (IDA)
sorting endosome  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal accessory olfactory bulb morphology  (IAGP)
abnormal aortic arch and aortic arch branch attachment  (IAGP)
abnormal auditory brainstem response  (IEA)
abnormal axon guidance  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal brain vasculature morphology  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cerebral cortex pyramidal cell morphology  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal coronary vessel morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal facial motor nucleus morphology  (IAGP)
abnormal facial nerve morphology  (IAGP)
abnormal first pharyngeal arch artery morphology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal induced retina neovascularization  (IAGP)
abnormal olfactory bulb development  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pulmonary artery morphology  (IAGP)
abnormal retina blood vessel morphology  (IAGP)
abnormal retina blood vessel pattern  (IAGP)
abnormal retina vasculature morphology  (IAGP)
abnormal second pharyngeal arch artery morphology  (IAGP)
abnormal sixth pharyngeal arch artery morphology  (IAGP)
abnormal spinal nerve morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal third pharyngeal arch artery morphology  (IAGP)
abnormal trigeminal nerve morphology  (IAGP)
abnormal vascular development  (IAGP)
abnormal vestibulocochlear nerve morphology  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
decreased angiogenesis  (IAGP)
decreased body size  (IAGP)
decreased embryo size  (IAGP)
decreased gonadotropin-releasing hormone neuron number  (IAGP)
decreased prepulse inhibition  (IEA)
decreased tumor growth/size  (IAGP)
delayed neuronal migration  (IAGP)
dilated heart atrium  (IAGP)
disorganized yolk sac vascular plexus  (IAGP)
double aortic arch  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
failure of vascular branching  (IAGP)
hemorrhage  (IAGP)
increased heart atrium size  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistent truncus arteriosus  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
right aortic arch  (IAGP)
transposition of great arteries  (IAGP)
vascular smooth muscle hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity. Cantuti-Castelvetri L, etal., Science. 2020 Nov 13;370(6518):856-860. doi: 10.1126/science.abd2985. Epub 2020 Oct 20.
2. Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons. Cloutier JF, etal., Neuron 2002 Mar 14;33(6):877-92.
3. Expression of VEGFR2 and NRP-1 in non-small cell lung cancer and their clinical significance. Ding M, etal., Chin J Cancer Res. 2014 Dec;26(6):669-77. doi: 10.3978/j.issn.1000-9604.2014.12.04.
4. Functional polymorphisms of the neuropilin 1 gene are associated with the risk of tetralogy of Fallot in a Chinese Han population. Fan SH, etal., Gene. 2018 May 5;653:72-79. doi: 10.1016/j.gene.2018.02.027. Epub 2018 Feb 10.
5. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. He Z and Tessier-Lavigne M, Cell 1997 Aug 22;90(4):739-51.
6. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
7. Effects of experimental type 1 diabetes and exercise training on angiogenic gene expression and capillarization in skeletal muscle. Kivela R, etal., FASEB J. 2006 Jul;20(9):1570-2.
8. Long non-coding RNA THRIL inhibits miRNA-24-3p to upregulate neuropilin-1 to aggravate cerebral ischemia-reperfusion injury through regulating the nuclear factor κB p65 signaling. Kuai F, etal., Aging (Albany NY). 2021 Mar 6;13(6):9071-9084. doi: 10.18632/aging.202762. Epub 2021 Mar 6.
9. Identifying New COVID-19 Receptor Neuropilin-1 in Severe Alzheimer's Disease Patients Group Brain Using Genome-Wide Association Study Approach. Lim KH, etal., Front Genet. 2021 Oct 21;12:741175. doi: 10.3389/fgene.2021.741175. eCollection 2021.
10. MGDs mouse GO annotations MGD data from the GO Consortium
11. MGD IEA MGD IEA
12. Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma. Morin E, etal., J Pathol. 2020 Apr;250(4):387-396. doi: 10.1002/path.5380. Epub 2020 Jan 29.
13. VEGF receptor signalling - in control of vascular function. Olsson AK, etal., Nat Rev Mol Cell Biol. 2006 May;7(5):359-71.
14. Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Pellet-Many C, etal., Cardiovasc Res. 2015 Nov 1;108(2):288-98. doi: 10.1093/cvr/cvv229. Epub 2015 Sep 25.
15. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes. Sola S, etal., Hepatology. 2005 Oct;42(4):925-34.
19. The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress. Wang J, etal., PLoS One. 2015 Nov 10;10(11):e0142571. doi: 10.1371/journal.pone.0142571. eCollection 2015.
20. SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment. Wu CT, etal., Cell Metab. 2021 Aug 3;33(8):1565-1576.e5. doi: 10.1016/j.cmet.2021.05.013. Epub 2021 May 18.
21. Ganoderma lucidum polysaccharides ameliorate lipopolysaccharide-induced acute pneumonia via inhibiting NRP1-mediated inflammation. Zhang X, etal., Pharm Biol. 2022 Dec;60(1):2201-2209. doi: 10.1080/13880209.2022.2142615.
22. Peritumoral Neuropilin-1 and VEGF receptor-2 expression increases time to recurrence in hepatocellular carcinoma patients undergoing curative hepatectomy. Zhuang PY, etal., Oncotarget. 2014 Nov 30;5(22):11121-32. doi: 10.18632/oncotarget.2553.
Additional References at PubMed
PMID:8575331   PMID:8748368   PMID:9331348   PMID:9390514   PMID:9742149   PMID:9753685   PMID:9811588   PMID:10229225   PMID:10328887   PMID:10349636   PMID:10409677   PMID:10414980  
PMID:10518505   PMID:10520994   PMID:10675351   PMID:10705382   PMID:10707970   PMID:10725340   PMID:10842181   PMID:11025205   PMID:11027230   PMID:11042159   PMID:11076861   PMID:11084652  
PMID:11108845   PMID:11160433   PMID:11165481   PMID:11231073   PMID:11238106   PMID:11442635   PMID:11461151   PMID:11486090   PMID:11688557   PMID:11756651   PMID:11786422   PMID:11804779  
PMID:11830568   PMID:11891274   PMID:11939589   PMID:12036513   PMID:12093729   PMID:12118260   PMID:12361971   PMID:12401447   PMID:12406894   PMID:12466851   PMID:12477932   PMID:12539040  
PMID:12577308   PMID:12591607   PMID:12821380   PMID:12852851   PMID:12897243   PMID:12950083   PMID:13678594   PMID:14516677   PMID:14722611   PMID:14973295   PMID:15019939   PMID:15051154  
PMID:15073150   PMID:15107403   PMID:15121176   PMID:15211465   PMID:15229182   PMID:15239958   PMID:15376331   PMID:15457507   PMID:15510105   PMID:15545635   PMID:15550623   PMID:15601855  
PMID:15604101   PMID:15632069   PMID:15673567   PMID:15677725   PMID:15782199   PMID:15814792   PMID:15814794   PMID:15869472   PMID:15875024   PMID:15920019   PMID:15978582   PMID:16107612  
PMID:16107693   PMID:16141072   PMID:16141073   PMID:16202709   PMID:16328161   PMID:16360650   PMID:16364899   PMID:16439477   PMID:16540575   PMID:16602821   PMID:16638018   PMID:16678147  
PMID:16687132   PMID:16799060   PMID:16964442   PMID:17145500   PMID:17222790   PMID:17259176   PMID:17360927   PMID:17362911   PMID:17374393   PMID:17428830   PMID:17537788   PMID:17573777  
PMID:17626059   PMID:17951031   PMID:17981115   PMID:18024993   PMID:18054858   PMID:18059265   PMID:18077678   PMID:18093989   PMID:18180379   PMID:18199763   PMID:18209113   PMID:18249526  
PMID:18287559   PMID:18300426   PMID:18328743   PMID:18345009   PMID:18356247   PMID:18381067   PMID:18384522   PMID:18436584   PMID:18463314   PMID:18464795   PMID:18480752   PMID:18483557  
PMID:18483621   PMID:18489001   PMID:18550715   PMID:18550718   PMID:18570254   PMID:18574596   PMID:18617019   PMID:18628209   PMID:18662545   PMID:18723443   PMID:18727829   PMID:18757501  
PMID:18786357   PMID:18804103   PMID:19037249   PMID:19144568   PMID:19165826   PMID:19175293   PMID:19261698   PMID:19296474   PMID:19325129   PMID:19332558   PMID:19357391   PMID:19364973  
PMID:19386662   PMID:19403658   PMID:19421194   PMID:19520907   PMID:19589963   PMID:19590177   PMID:19644017   PMID:19655386   PMID:19699520   PMID:19705428   PMID:19706882   PMID:19805273  
PMID:19812329   PMID:19837659   PMID:19859539   PMID:19961580   PMID:20010807   PMID:20039409   PMID:20071458   PMID:20072992   PMID:20133938   PMID:20298787   PMID:20339091   PMID:20345923  
PMID:20392836   PMID:20404134   PMID:20434998   PMID:20512151   PMID:20568246   PMID:20577048   PMID:20584329   PMID:20621059   PMID:20675371   PMID:20687910   PMID:20723208   PMID:20919742  
PMID:20978081   PMID:21059704   PMID:21071672   PMID:21075075   PMID:21147989   PMID:21173261   PMID:21245328   PMID:21267068   PMID:21270798   PMID:21305474   PMID:21338642   PMID:21364975  
PMID:21421844   PMID:21508241   PMID:21525298   PMID:21596842   PMID:21653940   PMID:21658586   PMID:21658587   PMID:21658588   PMID:21693521   PMID:21714103   PMID:21734098   PMID:21793101  
PMID:21828096   PMID:21852397   PMID:21862448   PMID:21873635   PMID:21925156   PMID:21947380   PMID:22012397   PMID:22025255   PMID:22051878   PMID:22082309   PMID:22096573   PMID:22213797  
PMID:22237885   PMID:22364862   PMID:22365545   PMID:22368082   PMID:22396765   PMID:22479201   PMID:22492355   PMID:22505034   PMID:22516460   PMID:22522930   PMID:22539416   PMID:22593055  
PMID:22615927   PMID:22632726   PMID:22683681   PMID:22705479   PMID:22723296   PMID:22723300   PMID:22738912   PMID:22745317   PMID:22790009   PMID:22885184   PMID:22906231   PMID:22927827  
PMID:22966001   PMID:22966003   PMID:22981605   PMID:23039190   PMID:23042737   PMID:23045606   PMID:23063659   PMID:23104057   PMID:23251405   PMID:23315162   PMID:23395374   PMID:23395391  
PMID:23406903   PMID:23416452   PMID:23563309   PMID:23602477   PMID:23639442   PMID:23649798   PMID:23685842   PMID:23709645   PMID:23713442   PMID:23716698   PMID:23803732   PMID:23812756  
PMID:23894673   PMID:23913274   PMID:23926254   PMID:23988635   PMID:23991118   PMID:24021649   PMID:24033337   PMID:24093675   PMID:24139045   PMID:24179230   PMID:24210822   PMID:24262984  
PMID:24276892   PMID:24292713   PMID:24332039   PMID:24360543   PMID:24401374   PMID:24561343   PMID:24574008   PMID:24586749   PMID:24618750   PMID:24776795   PMID:24791743   PMID:24809797  
PMID:24863063   PMID:24885223   PMID:24906954   PMID:24912173   PMID:24918638   PMID:24952961   PMID:24977735   PMID:25072663   PMID:25077433   PMID:25091710   PMID:25139858   PMID:25161316  
PMID:25199687   PMID:25233427   PMID:25244320   PMID:25245111   PMID:25264302   PMID:25271625   PMID:25336744   PMID:25343644   PMID:25363691   PMID:25406396   PMID:25414188   PMID:25416424  
PMID:25497097   PMID:25512301   PMID:25519242   PMID:25659123   PMID:25691858   PMID:25721514   PMID:25839327   PMID:25843547   PMID:25855168   PMID:25922531   PMID:25924845   PMID:25958091  
PMID:25959730   PMID:26017771   PMID:26037503   PMID:26051942   PMID:26053665   PMID:26071364   PMID:26081042   PMID:26159543   PMID:26371509   PMID:26450880   PMID:26495986   PMID:26503042  
PMID:26525675   PMID:26534986   PMID:26586223   PMID:26620267   PMID:26630461   PMID:26633812   PMID:26708340   PMID:26804176   PMID:26830346   PMID:26877262   PMID:26880314   PMID:27035626  
PMID:27048738   PMID:27075020   PMID:27117252   PMID:27143756   PMID:27180624   PMID:27291295   PMID:27356767   PMID:27466379   PMID:27578798   PMID:27591257   PMID:27611684   PMID:27618676  
PMID:27732581   PMID:27760760   PMID:27787870   PMID:27789228   PMID:27798109   PMID:27815442   PMID:27819291   PMID:27821771   PMID:27835904   PMID:27844052   PMID:27858201   PMID:27988210  
PMID:28107458   PMID:28262664   PMID:28289053   PMID:28325756   PMID:28334861   PMID:28407732   PMID:28432397   PMID:28507510   PMID:28552348   PMID:28634350   PMID:28637841   PMID:28659345  
PMID:28667171   PMID:28676569   PMID:28706241   PMID:28731029   PMID:28751609   PMID:28835419   PMID:28835631   PMID:28874785   PMID:28887477   PMID:28887481   PMID:28893946   PMID:28924218  
PMID:28929539   PMID:29031500   PMID:29059172   PMID:29059194   PMID:29097606   PMID:29358640   PMID:29415620   PMID:29543041   PMID:29549139   PMID:29743476   PMID:29773646   PMID:29774231  
PMID:29779877   PMID:29898965   PMID:29901792   PMID:29934640   PMID:30093598   PMID:30118322   PMID:30237243   PMID:30355201   PMID:30392794   PMID:30550785   PMID:30587537   PMID:30589468  
PMID:30623799   PMID:30649916   PMID:30661929   PMID:30683854   PMID:30692543   PMID:30735130   PMID:31062503   PMID:31118303   PMID:31273213   PMID:31338035   PMID:31350177   PMID:31350404  
PMID:31430342   PMID:31474563   PMID:31578032   PMID:31597102   PMID:31666588   PMID:31740486   PMID:31868583   PMID:31934626   PMID:31995756   PMID:32140099   PMID:32500307   PMID:32553152  
PMID:32561725   PMID:32661362   PMID:32747526   PMID:32761635   PMID:32857879   PMID:32984348   PMID:33009002   PMID:33174445   PMID:33322598   PMID:33357457   PMID:33454003   PMID:33545088  
PMID:33830085   PMID:33859199   PMID:33876574   PMID:34007995   PMID:34039996   PMID:34230480   PMID:34321999   PMID:34344941   PMID:34758202   PMID:34821196   PMID:34848712   PMID:34860155  
PMID:34986653   PMID:35075279   PMID:35126469   PMID:35230240   PMID:35266581   PMID:35297995   PMID:35367368   PMID:35380991   PMID:35462405   PMID:35603221   PMID:35666215   PMID:35696571  
PMID:35858913   PMID:35874918   PMID:35918150   PMID:35927240   PMID:36069030   PMID:36082581   PMID:36173190   PMID:36266461   PMID:36284453   PMID:36399562   PMID:36476860   PMID:36549270  
PMID:36653359   PMID:36963389   PMID:36970722   PMID:37220183   PMID:37298722   PMID:37566909   PMID:37610874   PMID:37823339   PMID:38019895   PMID:38029264   PMID:38035105   PMID:38242992  
PMID:38280850   PMID:38347587   PMID:38355793   PMID:38374152   PMID:38381008   PMID:38499720   PMID:38636517   PMID:38729153   PMID:38789481   PMID:38923264   PMID:38977708   PMID:39109924  
PMID:39152101   PMID:39152112   PMID:39271675   PMID:40023160  


Genomics

Comparative Map Data
Nrp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398129,085,553 - 129,231,957 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8129,085,085 - 129,229,844 (+)EnsemblGRCm39 Ensembl
GRCm388128,358,591 - 128,505,476 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8128,358,604 - 128,503,363 (+)EnsemblGRCm38mm10GRCm38
MGSCv378130,882,973 - 131,029,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368131,228,923 - 131,389,437 (+)NCBIMGSCv36mm8
Celera8132,685,332 - 132,831,714 (+)NCBICelera
Cytogenetic Map8E2NCBI
cM Map875.78NCBI
NRP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381033,177,493 - 33,334,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1033,177,492 - 33,336,262 (-)EnsemblGRCh38hg38GRCh38
GRCh371033,466,421 - 33,623,595 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361033,506,432 - 33,663,839 (-)NCBINCBI36Build 36hg18NCBI36
Build 341033,506,432 - 33,663,476NCBI
Celera1033,231,763 - 33,389,179 (-)NCBICelera
Cytogenetic Map10p11.22NCBI
HuRef1033,186,444 - 33,343,500 (-)NCBIHuRef
CHM1_11033,468,091 - 33,625,451 (-)NCBICHM1_1
T2T-CHM13v2.01033,206,293 - 33,375,463 (-)NCBIT2T-CHM13v2.0
Nrp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81973,256,557 - 73,411,705 (+)NCBIGRCr8
mRatBN7.21956,359,455 - 56,514,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1956,359,455 - 56,513,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1963,149,364 - 63,302,459 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01964,009,290 - 64,162,389 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01966,091,958 - 66,245,057 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01961,332,351 - 61,486,166 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1961,332,351 - 61,485,858 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01971,984,687 - 72,138,092 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41958,332,004 - 58,487,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11958,337,063 - 58,492,741 (+)NCBI
Celera1955,693,756 - 55,846,090 (+)NCBICelera
Cytogenetic Map19q12NCBI
Nrp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554624,101,999 - 4,241,012 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554624,101,997 - 4,241,012 (+)NCBIChiLan1.0ChiLan1.0
NRP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2845,819,786 - 45,977,758 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11045,825,106 - 45,982,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01033,298,918 - 33,456,466 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11033,883,162 - 34,039,645 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1033,883,173 - 34,039,648 (-)Ensemblpanpan1.1panPan2
NRP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.123,416,062 - 3,553,929 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl23,413,821 - 3,552,483 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha23,515,185 - 3,653,323 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.023,710,166 - 3,848,420 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl23,710,304 - 3,848,417 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.123,489,029 - 3,627,209 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.023,524,020 - 3,661,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.023,642,794 - 3,780,784 (+)NCBIUU_Cfam_GSD_1.0
Nrp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934412,194,941 - 12,335,217 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365741,694,336 - 1,834,720 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365741,694,433 - 1,834,720 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1056,280,665 - 56,430,777 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11056,280,673 - 56,430,832 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21061,651,758 - 61,802,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NRP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1932,474,787 - 32,632,746 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl932,474,309 - 32,633,101 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605641,535,637 - 41,695,579 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248058,438,498 - 8,574,508 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248058,438,485 - 8,574,845 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nrp1
8313 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:831
Count of miRNA genes:451
Interacting mature miRNAs:557
Transcripts:ENSMUST00000026917
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357494Obsty2_mobesity 2 (mouse)Not determined896245241129745061Mouse
4141435Fbtq3_mfemoral bone trait QTL 3 (mouse)Not determined8100965309130127694Mouse
12904960Gmmq6_mgastrocnemius muscle mass QTL 6 (mouse)8111481497130127694Mouse
1357841Phdlc2_mplasma HDL cholesterol 2 (mouse)Not determined8125191161129745061Mouse
11252141Fdr2_mfat response to dietary restriction 2 (mouse)898390634130127694Mouse
1302105Im1_mImmunoregulatory 1 (mouse)Not determined899828531130127694Mouse
12880431Fgf23lq2_mFGF23 serum level QTL 2 (mouse)897626632130127694Mouse
1301080Sluc9_msusceptibility to lung cancer 9 (mouse)Not determined899828531130127694Mouse
10412274Leci1_mleukocyte endothelial cell interactions 1 (mouse)Not determined8110415083130127694Mouse
26884375Skwq2_mskull length QTL 2, 5 week (mouse)8120726739130027694Mouse
12904938Edlmmq7_mextensor digitorum longus muscle mass QTL 7 (mouse)8111481497130127694Mouse
10412273Fcd1_mfunctional capillary density 1 (mouse)Not determined8110415083130127694Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889726628130027694Mouse
14746994Manh65_mmandible shape 65 (mouse)8106489629130127694Mouse
1301481Lith11_mlithogenic gene 11 (mouse)Not determined898563635130127694Mouse
11532692Sluc38a_msusceptibility to lung cancer 38a (mouse)8105033977130127694Mouse
11532691Sluc38_msusceptibility to lung cancer 38 (mouse)8105033977130127694Mouse

Markers in Region
Nrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv378131,026,693 - 131,027,083UniSTSGRCm37
MGSCv378130,992,262 - 130,992,578UniSTSGRCm37
Celera8132,829,032 - 132,829,422UniSTS
Celera8132,794,702 - 132,795,018UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
RH127171  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,414,334 - 128,414,566UniSTSGRCm38
MGSCv378130,938,234 - 130,938,466UniSTSGRCm37
Celera8132,740,687 - 132,740,919UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
Whitehead/MRC_RH81517.13UniSTS
RH134538  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,505,192 - 128,505,357UniSTSGRCm38
MGSCv378131,029,092 - 131,029,257UniSTSGRCm37
Celera8132,831,430 - 132,831,595UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
AI121036  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,453,396 - 128,453,477UniSTSGRCm38
MGSCv378130,977,296 - 130,977,377UniSTSGRCm37
Celera8132,779,720 - 132,779,801UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
Whitehead/MRC_RH81552.26UniSTS
D50086  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,503,122 - 128,503,226UniSTSGRCm38
MGSCv378131,027,022 - 131,027,126UniSTSGRCm37
Celera8132,829,361 - 132,829,465UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
Whitehead/MRC_RH81521.17UniSTS
Nrp  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,476,177 - 128,476,253UniSTSGRCm38
MGSCv378131,000,077 - 131,000,153UniSTSGRCm37
Celera8132,802,501 - 132,802,577UniSTS
Cytogenetic Map8EUniSTS
cM Map873.0UniSTS
Nrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,502,793 - 128,503,183UniSTSGRCm38
MGSCv378131,026,693 - 131,027,083UniSTSGRCm37
Celera8132,829,032 - 132,829,422UniSTS
Cytogenetic Map8EUniSTS
Nrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388128,468,362 - 128,468,678UniSTSGRCm38
MGSCv378130,992,262 - 130,992,578UniSTSGRCm37
Celera8132,794,702 - 132,795,018UniSTS
Cytogenetic Map8EUniSTS
Nrp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8EUniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF482432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS067212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS486925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D50086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000026917   ⟹   ENSMUSP00000026917
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8129,085,765 - 129,229,844 (+)Ensembl
GRCm38.p6 Ensembl8128,359,284 - 128,503,363 (+)Ensembl
Ensembl Acc Id: ENSMUST00000212746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8129,085,554 - 129,154,950 (+)Ensembl
GRCm38.p6 Ensembl8128,359,073 - 128,428,469 (+)Ensembl
Ensembl Acc Id: ENSMUST00000212833
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8129,085,085 - 129,091,901 (+)Ensembl
GRCm38.p6 Ensembl8128,358,604 - 128,365,420 (+)Ensembl
Ensembl Acc Id: ENSMUST00000212933
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8129,085,878 - 129,188,562 (+)Ensembl
GRCm38.p6 Ensembl8128,359,397 - 128,462,081 (+)Ensembl
RefSeq Acc Id: NM_001358959   ⟹   NP_001345888
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398129,085,553 - 129,231,957 (+)NCBI
GRCm388128,359,073 - 128,505,476 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001358960   ⟹   NP_001345889
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398129,085,553 - 129,231,957 (+)NCBI
GRCm388128,359,073 - 128,505,476 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001424858   ⟹   NP_001411787
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398129,085,553 - 129,231,957 (+)NCBI
RefSeq Acc Id: NM_001424859   ⟹   NP_001411788
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398129,085,553 - 129,203,890 (+)NCBI
RefSeq Acc Id: NM_008737   ⟹   NP_032763
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398129,085,553 - 129,231,957 (+)NCBI
GRCm388128,359,073 - 128,505,476 (+)NCBI
MGSCv378130,882,973 - 131,029,376 (+)RGD
Celera8132,685,332 - 132,831,714 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032763   ⟸   NM_008737
- Peptide Label: isoform 1 precursor
- UniProtKB: Q6PAR3 (UniProtKB/Swiss-Prot),   P97333 (UniProtKB/Swiss-Prot),   Q3UQY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345889   ⟸   NM_001358960
- Peptide Label: isoform 3 precursor
- UniProtKB: Q3UQY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345888   ⟸   NM_001358959
- Peptide Label: isoform 2 precursor
- UniProtKB: Q3UQY7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000026917   ⟸   ENSMUST00000026917
RefSeq Acc Id: NP_001411787   ⟸   NM_001424858
- Peptide Label: isoform 4 precursor
- UniProtKB: Q3UQY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001411788   ⟸   NM_001424859
- Peptide Label: isoform 5 precursor
Protein Domains
CUB   F5/8 type C   MAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97333-F1-model_v2 AlphaFold P97333 1-923 view protein structure

Promoters
RGD ID:8668696
Promoter ID:EPDNEW_M12379
Type:multiple initiation site
Name:Nrp1_1
Description:Mus musculus neuropilin 1 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12381  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388128,359,072 - 128,359,132EPDNEW
RGD ID:8668700
Promoter ID:EPDNEW_M12381
Type:initiation region
Name:Nrp1_2
Description:Mus musculus neuropilin 1 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M12379  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388128,359,393 - 128,359,453EPDNEW
RGD ID:6849258
Promoter ID:MM_XEF:7296
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:NM_145098
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368130,880,916 - 130,881,647 (+)MPROMDB
RGD ID:6843581
Promoter ID:MM_KWN:56246
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000122574,   NM_008737,   UC009NZQ.1,   UC009NZR.1,   UC009NZS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv368130,881,946 - 130,883,457 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106206 AgrOrtholog
Ensembl Genes ENSMUSG00000025810 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000026917 ENTREZGENE
  ENSMUST00000026917.10 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot
  2.60.120.290 UniProtKB/Swiss-Prot
  Galactose-binding domain-like UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  CUB_dom UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  MAM_dom UniProtKB/Swiss-Prot
  Neuropilin UniProtKB/Swiss-Prot
  Neuropilin_C UniProtKB/Swiss-Prot
  Neuropilin_MCO_CoagFactor UniProtKB/Swiss-Prot
  Sperma_CUB_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:18186 UniProtKB/Swiss-Prot
MGD MGI:106206 ENTREZGENE
NCBI Gene 18186 ENTREZGENE
PANTHER F5/8 TYPE C DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  PTHR46806:SF4 UniProtKB/Swiss-Prot
Pfam CUB UniProtKB/Swiss-Prot
  DUF3481 UniProtKB/Swiss-Prot
  F5_F8_type_C UniProtKB/Swiss-Prot
  MAM UniProtKB/Swiss-Prot
PhenoGen Nrp1 PhenoGen
PIRSF Neuropilin UniProtKB/Swiss-Prot
PRINTS MAMDOMAIN UniProtKB/Swiss-Prot
PROSITE CUB UniProtKB/Swiss-Prot
  FA58C_1 UniProtKB/Swiss-Prot
  FA58C_2 UniProtKB/Swiss-Prot
  FA58C_3 UniProtKB/Swiss-Prot
  MAM_1 UniProtKB/Swiss-Prot
  MAM_2 UniProtKB/Swiss-Prot
SMART CUB UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  MAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49785 UniProtKB/Swiss-Prot
  SSF49854 UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot
UniProt NRP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UFP7_MOUSE UniProtKB/TrEMBL
  Q3UQY7 ENTREZGENE, UniProtKB/TrEMBL
  Q6PAR3 ENTREZGENE
  Q80X28_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6PAR3 UniProtKB/Swiss-Prot