Pdgfra (platelet derived growth factor receptor, alpha polypeptide) - Rat Genome Database

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Gene: Pdgfra (platelet derived growth factor receptor, alpha polypeptide) Mus musculus
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Symbol: Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
RGD ID: 11069
MGI Page MGI
Description: Enables platelet-derived growth factor alpha-receptor activity and platelet-derived growth factor binding activity. Involved in several processes, including animal organ development; platelet-derived growth factor receptor-alpha signaling pathway; and protein phosphorylation. Acts upstream of or within several processes, including animal organ development; face morphogenesis; and signal transduction involved in regulation of gene expression. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and microvillus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and heart and pericardium. Used to study congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypereosinophilic syndrome; and pancreatic cancer. Orthologous to human PDGFRA (platelet derived growth factor receptor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI115593; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; CD140; CD140 antigen-like family member A; CD140a; PDGF alpha chain; PDGF-R-alpha; Pdgfr; Pdgfr-2; PDGFR-alpha; platelet-derived growth factor alpha receptor; platelet-derived growth factor receptor alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39575,311,988 - 75,358,867 (+)NCBIGRCm39mm39
GRCm39 Ensembl575,312,953 - 75,358,876 (+)Ensembl
GRCm38575,151,322 - 75,198,206 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl575,152,292 - 75,198,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv37575,548,316 - 75,594,229 (+)NCBIGRCm37mm9NCBIm37
MGSCv36575,434,045 - 75,479,893 (+)NCBImm8
Celera572,441,591 - 72,487,596 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
B-lymphoblastic leukemia/lymphoma  (IDA)
Brain Injuries  (ISO)
brain stem glioma  (ISO)
breast carcinoma  (ISO)
Chronic Allograft Nephropathy  (ISO)
chronic ulcer of skin  (ISO)
cleft palate  (ISO)
colon carcinoma  (ISO)
congenital diaphragmatic hernia  (IEA)
congestive heart failure  (ISO)
Craniofacial Abnormalities  (ISO)
craniopharyngioma  (ISO)
Endometrioid Carcinomas  (ISO)
Eosinophilia  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Fetal Death  (ISO)
gastrointestinal stromal tumor  (ISO)
Germ Cell and Embryonal Neoplasms  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
hypereosinophilic syndrome  (ISO)
Hyperoxia  (ISO)
hypertension  (ISO)
in situ carcinoma  (ISO)
isolated cleft palate  (ISO)
Kidney Reperfusion Injury  (ISO)
leukemia  (ISO)
Leydig cell tumor  (ISO)
lung disease  (ISO)
lung squamous cell carcinoma  (ISO)
medulloblastoma  (ISO)
melanoma  (ISO)
mesenchymal chondrosarcoma  (ISO)
middle cerebral artery infarction  (ISO)
Multiple Polyps and Recurrent Inflammatory Fibroid, Gastrointestinal  (ISO)
myeloid leukemia  (ISO)
myeloid sarcoma  (ISO)
Neointima  (ISO)
oligohydramnios  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
Pdgfra-Associated Chronic Eosinophilic Leukemia  (ISO)
prostate adenocarcinoma  (ISO)
pulmonary fibrosis  (ISO)
renal cell carcinoma  (ISO)
Respiratory System Abnormalities  (ISO)
sciatic neuropathy  (ISO)
seminoma  (ISO)
spina bifida  (ISO)
Stroke  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
Uterine Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,2-(2-Chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbofuran  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDD  (ISO)
DDE  (ISO)
DDT  (ISO)
dermatan sulfate  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP,ISO)
diuron  (ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furosemide  (ISO)
genistein  (ISO)
heparin  (ISO)
hydrogen peroxide  (EXP,ISO)
indometacin  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
lovastatin  (ISO)
maneb  (EXP)
masitinib  (ISO)
melatonin  (EXP)
methamphetamine  (ISO)
methylisothiazolinone  (ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
monosodium L-glutamate  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
nitrofen  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP)
oxycodone  (ISO)
p-toluidine  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
PCB138  (EXP)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (EXP)
pirinixic acid  (ISO)
ponatinib  (ISO)
potassium dichromate  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium chloride  (ISO)
sorafenib  (ISO)
streptozocin  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vismodegib  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal gland development  (IGI)
aging  (ISO)
anatomical structure morphogenesis  (IMP)
animal organ morphogenesis  (IMP)
brain development  (ISO)
cardiac myofibril assembly  (IGI)
cell chemotaxis  (IMP,ISO)
cell migration  (IMP)
cellular response to amino acid stimulus  (IDA)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to reactive oxygen species  (ISO)
chemotaxis  (IEA)
embryonic cranial skeleton morphogenesis  (IBA,IMP)
embryonic digestive tract morphogenesis  (IMP)
estrogen metabolic process  (IGI)
extracellular matrix organization  (IMP)
face morphogenesis  (IMP)
female gonad development  (IGI)
hematopoietic progenitor cell differentiation  (IMP)
in utero embryonic development  (IMP)
inner ear development  (ISO)
Leydig cell differentiation  (IMP)
lung development  (IMP)
lung growth  (ISO)
luteinization  (IGI,IMP)
male genitalia development  (IMP)
male gonad development  (ISO)
metanephric glomerular capillary formation  (IGI)
negative regulation of platelet activation  (ISO)
odontogenesis of dentin-containing tooth  (IMP)
peptidyl-tyrosine phosphorylation  (IDA,ISO)
phosphatidylinositol-mediated signaling  (ISO)
phosphorylation  (IEA)
platelet aggregation  (ISO)
platelet-derived growth factor receptor signaling pathway  (IMP,ISO)
platelet-derived growth factor receptor-alpha signaling pathway  (IDA,ISO)
positive regulation of branching involved in lung morphogenesis  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of kinase activity  (IBA)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase activity  (ISO)
positive regulation of phospholipase C activity  (ISO)
protein autophosphorylation  (IDA,ISO)
protein phosphorylation  (IEA)
regulation of chemotaxis  (ISO)
regulation of mesenchymal stem cell differentiation  (ISO)
response to cytokine  (ISO)
response to estradiol  (ISO)
response to estrogen  (ISO)
response to formaldehyde  (ISO)
response to hormone  (ISO)
response to hyperoxia  (ISO)
response to inorganic substance  (ISO)
response to organic substance  (ISO)
retina vasculature development in camera-type eye  (IGI)
roof of mouth development  (IMP)
signal transduction involved in regulation of gene expression  (IDA)
skeletal system morphogenesis  (IMP)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
white fat cell differentiation  (IMP)
wound healing  (IMP,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adrenal cortex morphology  (IAGP)
abnormal adrenal gland morphology  (IAGP)
abnormal cardiac neural crest cell migration  (IAGP)
abnormal cecum morphology  (IAGP)
abnormal cell migration  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal cranial neural crest cell morphology  (IAGP)
abnormal diaphragm development  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal frontonasal prominence morphology  (IAGP)
abnormal heart septum morphology  (IAGP)
abnormal hematopoietic cell number  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal kidney pelvis morphology  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal lung development  (IAGP)
abnormal lung morphology  (IAGP)
abnormal mesenchyme morphology  (IAGP)
abnormal myelination  (IAGP)
abnormal myotome development  (IAGP)
abnormal myotome morphology  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal nasal capsule morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal oligodendrocyte morphology  (IAGP)
abnormal ovarian follicle morphology  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal pectoral girdle bone morphology  (IAGP)
abnormal placenta development  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal pubis morphology  (IAGP)
abnormal pulmonary alveolar parenchyma morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal rib joint morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal scapula morphology  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal small intestine morphology  (IAGP)
abnormal spermatocyte morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal stomach morphology  (IAGP)
abnormal testis cord formation  (IAGP)
abnormal testis morphology  (IAGP)
abnormal testosterone level  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal thymus development  (IAGP)
abnormal trophoblast layer morphology  (IAGP)
abnormal ureter development  (IAGP)
abnormal ureter morphology  (IAGP)
abnormal ureter smooth muscle morphology  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal vasculogenesis  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent corpus luteum  (IAGP)
absent primitive endoderm  (IAGP)
absent roof plate  (IAGP)
absent sternum  (IAGP)
absent zygomatic bone  (IAGP)
acromion hypoplasia  (IAGP)
anemia  (IAGP)
anovulation  (IAGP)
broad snout  (IAGP)
cardiac fibrosis  (IAGP)
cleft palate  (IAGP)
cleft secondary palate  (IAGP)
cyanosis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased corpora lutea number  (IAGP)
decreased cranium height  (IAGP)
decreased embryo size  (IAGP)
decreased length of long bones  (IAGP)
decreased Leydig cell number  (IAGP)
decreased oligodendrocyte progenitor number  (IAGP)
decreased secondary ovarian follicle number  (IAGP)
decreased theca cell number  (IAGP)
delayed fertility  (IAGP)
delayed heart development  (IAGP)
diaphragmatic hernia  (IAGP)
dilated ureter  (IAGP)
ectopic cranial bone  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
emphysema  (IAGP)
enlarged placenta  (IAGP)
esophagus hyperplasia  (IAGP)
failure of chorioallantoic fusion  (IAGP)
failure of initiation of embryo turning  (IAGP)
failure of somite differentiation  (IAGP)
female infertility  (IAGP)
fetal bleb  (IAGP)
glomerulosclerosis  (IAGP)
hemorrhage  (IAGP)
herniated abdominal wall  (IAGP)
hydronephrosis  (IAGP)
hydrops fetalis  (IAGP)
impaired ossification of basisphenoid bone  (IAGP)
incomplete embryo turning  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased apoptosis  (IAGP)
increased cell proliferation  (IAGP)
increased embryo size  (IAGP)
increased fetal size  (IAGP)
increased fibroblast chemotaxis  (IAGP)
increased fibroblast proliferation  (IAGP)
increased fibrosarcoma incidence  (IAGP)
increased mesenchymal cell proliferation involved in lung development  (IAGP)
increased sarcoma incidence  (IAGP)
intestinal fibrosis  (IAGP)
intestine polyps  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
male infertility  (IAGP)
midline facial cleft  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
open neural tube  (IAGP)
palatal shelves fail to meet at midline  (IAGP)
pallor  (IAGP)
pericardial edema  (IAGP)
perimembraneous ventricular septal defect  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistent truncus arteriosis  (IAGP)
polydactyly  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
pulmonary fibrosis  (IAGP)
pulmonary hyperplasia  (IAGP)
pulmonary hypoplasia  (IAGP)
renal glomerulus fibrosis  (IAGP)
renal glomerulus hypertrophy  (IAGP)
renal interstitial fibrosis  (IAGP)
respiratory failure  (IAGP)
retroesophageal right subclavian artery  (IAGP)
rib bifurcation  (IAGP)
rib fusion  (IAGP)
seizures  (IAGP)
short maxilla  (IAGP)
short nasal bone  (IAGP)
short premaxilla  (IAGP)
short snout  (IAGP)
short ureter  (IAGP)
skeletal muscle interstitial fibrosis  (IAGP)
skin edema  (IAGP)
skin fibrosis  (IAGP)
small adrenal glands  (IAGP)
small ovary  (IAGP)
small testis  (IAGP)
small thymus  (IAGP)
spina bifida  (IAGP)
testicular hemorrhage  (IAGP)
thin epidermis  (IAGP)
thymus hypoplasia  (IAGP)
tight skin  (IAGP)
tremors  (IAGP)
ureter obstruction  (IAGP)
uterus hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
wavy neural tube  (IAGP)
wide sternum  (IAGP)
References

References - curated
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Additional References at PubMed
PMID:863250   PMID:1292572   PMID:1315306   PMID:1321404   PMID:1322269   PMID:1322271   PMID:1372902   PMID:1451656   PMID:1638976   PMID:1647018   PMID:1683707   PMID:1711190  
PMID:1711435   PMID:1717995   PMID:1846043   PMID:1869533   PMID:2155144   PMID:2174116   PMID:2536956   PMID:2980249   PMID:5529676   PMID:6510711   PMID:6628990   PMID:7502236  
PMID:7537231   PMID:7537375   PMID:7540588   PMID:7542761   PMID:7550316   PMID:7579892   PMID:7588258   PMID:7649812   PMID:7678927   PMID:7720681   PMID:7893599   PMID:7958864  
PMID:8011581   PMID:8041746   PMID:8041773   PMID:8043948   PMID:8244376   PMID:8589683   PMID:8643452   PMID:8660874   PMID:8661727   PMID:8681381   PMID:8806824   PMID:8875964  
PMID:8879750   PMID:8889548   PMID:8901196   PMID:8922682   PMID:8933762   PMID:8954727   PMID:9142500   PMID:9183385   PMID:9199674   PMID:9211853   PMID:9215907   PMID:9226440  
PMID:9233543   PMID:9242497   PMID:9373024   PMID:9374392   PMID:9472924   PMID:9486531   PMID:9493833   PMID:9510033   PMID:9620692   PMID:9653117   PMID:9734598   PMID:9763477  
PMID:9778496   PMID:9811881   PMID:9828088   PMID:9853970   PMID:9884514   PMID:10036240   PMID:10036976   PMID:10208749   PMID:10231569   PMID:10331973   PMID:10347229   PMID:10349636  
PMID:10357934   PMID:10364225   PMID:10366628   PMID:10395790   PMID:10411402   PMID:10419690   PMID:10477764   PMID:10585775   PMID:10589677   PMID:10603348   PMID:10652278   PMID:10719888  
PMID:10719889   PMID:10806482   PMID:10837138   PMID:10885750   PMID:10903171   PMID:10922068   PMID:10944220   PMID:11023856   PMID:11034547   PMID:11042159   PMID:11044607   PMID:11076861  
PMID:11114734   PMID:11171336   PMID:11217851   PMID:11239463   PMID:11329183   PMID:11414789   PMID:11437453   PMID:11472850   PMID:11493571   PMID:11526078   PMID:11544480   PMID:11588182  
PMID:11640898   PMID:11748136   PMID:11748155   PMID:11782318   PMID:11799060   PMID:11803579   PMID:11809759   PMID:11830569   PMID:11955448   PMID:12072567   PMID:12186854   PMID:12403705  
PMID:12441294   PMID:12466851   PMID:12477932   PMID:12490199   PMID:12490557   PMID:12651897   PMID:12736344   PMID:12748302   PMID:12756179   PMID:12835383   PMID:12837627   PMID:12842915  
PMID:12874134   PMID:12930780   PMID:12966207   PMID:14506245   PMID:14514732   PMID:14522834   PMID:14534257   PMID:14602683   PMID:14624252   PMID:14644164   PMID:14648547   PMID:14648841  
PMID:14681479   PMID:14699583   PMID:14993293   PMID:15059936   PMID:15085178   PMID:15096597   PMID:15183724   PMID:15207855   PMID:15211353   PMID:15221957   PMID:15226823   PMID:15229650  
PMID:15254900   PMID:15254974   PMID:15306695   PMID:15361870   PMID:15371303   PMID:15371513   PMID:15372073   PMID:15525682   PMID:15531362   PMID:15533830   PMID:15543606   PMID:15581876  
PMID:15629701   PMID:15629702   PMID:15708558   PMID:15756692   PMID:15811134   PMID:15837572   PMID:15880651   PMID:15893981   PMID:15932761   PMID:15976074   PMID:15979417   PMID:16141072  
PMID:16141073   PMID:16162653   PMID:16199865   PMID:16224065   PMID:16243034   PMID:16330018   PMID:16336945   PMID:16354679   PMID:16407399   PMID:16452166   PMID:16462734   PMID:16469306  
PMID:16481423   PMID:16530748   PMID:16602821   PMID:16690743   PMID:16823490   PMID:16846854   PMID:16908628   PMID:16971512   PMID:17003488   PMID:17028112   PMID:17084361   PMID:17143286  
PMID:17328885   PMID:17344230   PMID:17350578   PMID:17391983   PMID:17442300   PMID:17442807   PMID:17499702   PMID:17537790   PMID:17568391   PMID:17625108   PMID:17634372   PMID:17678855  
PMID:18031722   PMID:18038259   PMID:18070887   PMID:18184658   PMID:18184726   PMID:18192285   PMID:18194151   PMID:18287559   PMID:18297729   PMID:18323664   PMID:18383037   PMID:18448566  
PMID:18462699   PMID:18515427   PMID:18521186   PMID:18559345   PMID:18606782   PMID:18625210   PMID:18651661   PMID:18676816   PMID:18725515   PMID:18799693   PMID:18833569   PMID:18927153  
PMID:18948621   PMID:19007884   PMID:19015638   PMID:19047372   PMID:19056881   PMID:19126548   PMID:19135046   PMID:19141668   PMID:19164599   PMID:19217431   PMID:19217896   PMID:19234195  
PMID:19280210   PMID:19325248   PMID:19334281   PMID:19334288   PMID:19483677   PMID:19498055   PMID:19502291   PMID:19503085   PMID:19515974   PMID:19538749   PMID:19632216   PMID:19633290  
PMID:19682908   PMID:19690384   PMID:19723505   PMID:19741146   PMID:19806666   PMID:19838178   PMID:19841085   PMID:19853842   PMID:19897741   PMID:19910576   PMID:19935654   PMID:19939260  
PMID:20071345   PMID:20081190   PMID:20091777   PMID:20110689   PMID:20237296   PMID:20299672   PMID:20356956   PMID:20368359   PMID:20371769   PMID:20388654   PMID:20489144   PMID:20548288  
PMID:20554876   PMID:20619341   PMID:20621681   PMID:20643125   PMID:20648636   PMID:20658695   PMID:20825492   PMID:20826533   PMID:20943929   PMID:21072194   PMID:21146513   PMID:21181412  
PMID:21205786   PMID:21210220   PMID:21220101   PMID:21238928   PMID:21245162   PMID:21267068   PMID:21310211   PMID:21335239   PMID:21343363   PMID:21350214   PMID:21386911   PMID:21393858  
PMID:21438071   PMID:21451043   PMID:21464317   PMID:21512159   PMID:21536740   PMID:21539829   PMID:21545793   PMID:21576357   PMID:21659960   PMID:21685324   PMID:21715615   PMID:21768372  
PMID:21854849   PMID:21873635   PMID:21911838   PMID:21947380   PMID:21956870   PMID:21993628   PMID:22027834   PMID:22031549   PMID:22071102   PMID:22072979   PMID:22096072   PMID:22123957  
PMID:22151424   PMID:22230248   PMID:22264326   PMID:22265737   PMID:22293178   PMID:22322974   PMID:22365546   PMID:22390626   PMID:22411791   PMID:22424930   PMID:22431518   PMID:22433866  
PMID:22482730   PMID:22496664   PMID:22504067   PMID:22522171   PMID:22535408   PMID:22542597   PMID:22573622   PMID:22627280   PMID:22652199   PMID:22699898   PMID:22730381   PMID:22863011  
PMID:22898775   PMID:22901751   PMID:22940072   PMID:22960170   PMID:22972715   PMID:22975322   PMID:22998872   PMID:23019366   PMID:23023706   PMID:23056302   PMID:23148317   PMID:23160237  
PMID:23178882   PMID:23193166   PMID:23197710   PMID:23236457   PMID:23261931   PMID:23264740   PMID:23266329   PMID:23274689   PMID:23308235   PMID:23332759   PMID:23335233   PMID:23429582  
PMID:23434825   PMID:23448253   PMID:23466739   PMID:23469020   PMID:23482494   PMID:23499552   PMID:23529017   PMID:23545937   PMID:23555309   PMID:23575864   PMID:23582327   PMID:23583582  
PMID:23633653   PMID:23637331   PMID:23643936   PMID:23651855   PMID:23733391   PMID:23747191   PMID:23776077   PMID:23819440   PMID:23828719   PMID:23840809   PMID:23921127   PMID:23928059  
PMID:23929039   PMID:23938297   PMID:23946446   PMID:23948231   PMID:24000064   PMID:24011071   PMID:24029230   PMID:24043815   PMID:24046351   PMID:24047695   PMID:24086166   PMID:24131628  
PMID:24144881   PMID:24190966   PMID:24257626   PMID:24332837   PMID:24336287   PMID:24361597   PMID:24396055   PMID:24431450   PMID:24433583   PMID:24449836   PMID:24599474   PMID:24618081  
PMID:24667490   PMID:24703957   PMID:24733830   PMID:24763086   PMID:24788519   PMID:24835466   PMID:24859004   PMID:24886827   PMID:24917498   PMID:24929016   PMID:24948802   PMID:24952961  
PMID:25053429   PMID:25055825   PMID:25100655   PMID:25136113   PMID:25150063   PMID:25197048   PMID:25249462   PMID:25301187   PMID:25340657   PMID:25341729   PMID:25341788   PMID:25371364  
PMID:25378163   PMID:25382142   PMID:25408548   PMID:25470749   PMID:25568099   PMID:25568100   PMID:25588837   PMID:25605750   PMID:25631042   PMID:25683249   PMID:25708924   PMID:25730471  
PMID:25745058   PMID:25753732   PMID:25754822   PMID:25810530   PMID:25865047   PMID:25865356   PMID:25884589   PMID:25936505   PMID:25940087   PMID:25946682   PMID:25951516   PMID:25980517  
PMID:26019175   PMID:26049020   PMID:26053624   PMID:26138642   PMID:26146073   PMID:26202222   PMID:26250625   PMID:26320158   PMID:26345464   PMID:26390289   PMID:26414960   PMID:26434918  
PMID:26435273   PMID:26439735   PMID:26457609   PMID:26479710   PMID:26493106   PMID:26525805   PMID:26586200   PMID:26632490   PMID:26635390   PMID:26639755   PMID:26657772   PMID:26677825  
PMID:26697723   PMID:26721501   PMID:26745185   PMID:26798014   PMID:26811382   PMID:26821812   PMID:26837596   PMID:26869039   PMID:26878215   PMID:26902921   PMID:26928066   PMID:26940020  
PMID:26971580   PMID:26984772   PMID:26988758   PMID:27019112   PMID:27044077   PMID:27067865   PMID:27113764   PMID:27121621   PMID:27133129   PMID:27141870   PMID:27144456   PMID:27149841  
PMID:27213272   PMID:27265328   PMID:27280679   PMID:27287810   PMID:27348591   PMID:27364009   PMID:27376984   PMID:27416896   PMID:27469598   PMID:27513343   PMID:27516371   PMID:27569721  
PMID:27626655   PMID:27746098   PMID:27802136   PMID:27806288   PMID:27816607   PMID:27829154   PMID:27856617   PMID:27862528   PMID:27894125   PMID:28036337   PMID:28049691   PMID:28087629  
PMID:28089671   PMID:28098558   PMID:28111199   PMID:28129672   PMID:28195173   PMID:28215843   PMID:28237967   PMID:28323616   PMID:28330582   PMID:28336567   PMID:28336932   PMID:28378742  
PMID:28379539   PMID:28408205   PMID:28433542   PMID:28439006   PMID:28472653   PMID:28481328   PMID:28487538   PMID:28490013   PMID:28494873   PMID:28501760   PMID:28530121   PMID:28650345  
PMID:28668474   PMID:28683207   PMID:28714851   PMID:28775097   PMID:28806761   PMID:28809397   PMID:28818870   PMID:28819169   PMID:28827394   PMID:28848093   PMID:28870993   PMID:28875931  
PMID:28886382   PMID:28919111   PMID:28919262   PMID:28923828   PMID:28934221   PMID:28943241   PMID:28947535   PMID:28947806   PMID:28981898   PMID:29028795   PMID:29084951   PMID:29107533  
PMID:29115005   PMID:29122839   PMID:29158033   PMID:29158445   PMID:29230039   PMID:29237719   PMID:29251627   PMID:29290586   PMID:29341790   PMID:29360139   PMID:29361054   PMID:29378823  
PMID:29443965   PMID:29447006   PMID:29463737   PMID:29500351   PMID:29507409   PMID:29543041   PMID:29636361   PMID:29666241   PMID:29683222   PMID:29725010   PMID:29752282   PMID:29768404  
PMID:29920279   PMID:29953488   PMID:29990475   PMID:29999500   PMID:30016619   PMID:30026121   PMID:30057274   PMID:30078729   PMID:30082792   PMID:30111655   PMID:30121753   PMID:30153454  
PMID:30178747   PMID:30201265   PMID:30242047   PMID:30246400   PMID:30249802   PMID:30323271   PMID:30348676   PMID:30367038   PMID:30415836   PMID:30485861   PMID:30509307   PMID:30541888  
PMID:30550785   PMID:30595533   PMID:30595537   PMID:30604742   PMID:30604848   PMID:30606613   PMID:30635555   PMID:30648289   PMID:30654933   PMID:30675802   PMID:30724411   PMID:30735538  
PMID:30770339   PMID:30824323   PMID:30890337   PMID:30912746   PMID:30913328   PMID:30940539   PMID:30980466   PMID:30982771   PMID:30988300   PMID:31018125   PMID:31018126   PMID:31043608  
PMID:31071314   PMID:31076486   PMID:31081019   PMID:31091443   PMID:31092921   PMID:31125253   PMID:31167144   PMID:31185811   PMID:31246945   PMID:31331942   PMID:31345929   PMID:31792383  
PMID:31809738   PMID:31862844   PMID:31932351   PMID:31940496   PMID:31940497   PMID:31944179   PMID:32001436   PMID:32015540   PMID:32046118   PMID:32067289   PMID:32155439   PMID:32169553  
PMID:32186397   PMID:32229310   PMID:32266943   PMID:32274496   PMID:32278722   PMID:32295715   PMID:32322056   PMID:32353175   PMID:32385276   PMID:32394892   PMID:32434871   PMID:32442967  
PMID:32497091   PMID:32531084   PMID:32553115   PMID:32615075   PMID:32715478   PMID:32737331   PMID:32800757   PMID:32878924   PMID:32913108   PMID:32958928   PMID:33001865   PMID:33057360  
PMID:33060130   PMID:33108748   PMID:33132281   PMID:33147210   PMID:33168840   PMID:33174445   PMID:33224039   PMID:33259802   PMID:33277484   PMID:33302058   PMID:33306673   PMID:33309273  
PMID:33470182   PMID:33483579   PMID:33495473   PMID:33503976   PMID:33510480   PMID:33707239   PMID:33780134   PMID:33846639   PMID:33859199   PMID:33887203   PMID:33941693   PMID:33976153  
PMID:34079011   PMID:34158500   PMID:34222248   PMID:34336815   PMID:34429415  


Genomics

Comparative Map Data
Pdgfra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39575,311,988 - 75,358,867 (+)NCBIGRCm39mm39
GRCm39 Ensembl575,312,953 - 75,358,876 (+)Ensembl
GRCm38575,151,322 - 75,198,206 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl575,152,292 - 75,198,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv37575,548,316 - 75,594,229 (+)NCBIGRCm37mm9NCBIm37
MGSCv36575,434,045 - 75,479,893 (+)NCBImm8
Celera572,441,591 - 72,487,596 (+)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map539.55NCBI
PDGFRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl454,229,280 - 54,298,245 (+)EnsemblGRCh38hg38GRCh38
GRCh38454,229,127 - 54,298,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37455,095,460 - 55,164,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36454,790,204 - 54,859,169 (+)NCBINCBI36hg18NCBI36
Build 34454,936,129 - 55,005,339NCBI
Celera452,596,023 - 52,665,170 (+)NCBI
Cytogenetic Map4q12NCBI
HuRef451,043,324 - 51,112,555 (+)NCBIHuRef
CHM1_1455,130,846 - 55,199,987 (+)NCBICHM1_1
Pdgfra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21433,005,838 - 33,054,347 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1433,005,839 - 33,054,335 (-)Ensembl
Rnor_6.01435,527,926 - 35,581,130 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1435,527,927 - 35,581,031 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01435,356,434 - 35,409,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41435,369,422 - 35,418,126 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11435,369,672 - 35,418,126 (-)NCBI
Celera1432,273,077 - 32,324,887 (-)NCBICelera
RH 3.4 Map14432.47RGD
Cytogenetic Map14p11NCBI
Pdgfra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544716,569,909 - 16,612,373 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544716,570,652 - 16,613,410 (-)NCBIChiLan1.0ChiLan1.0
PDGFRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1476,200,871 - 76,271,105 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl476,199,382 - 76,271,097 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0469,639,081 - 69,709,870 (-)NCBIMhudiblu_PPA_v0panPan3
PDGFRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11346,729,722 - 46,775,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1346,730,703 - 46,773,278 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1346,687,151 - 46,733,378 (+)NCBI
ROS_Cfam_1.01347,339,954 - 47,386,179 (+)NCBI
UMICH_Zoey_3.11347,012,519 - 47,058,684 (+)NCBI
UNSW_CanFamBas_1.01346,544,815 - 46,590,877 (+)NCBI
UU_Cfam_GSD_1.01347,418,193 - 47,464,247 (+)NCBI
Pdgfra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528529,444,794 - 29,494,171 (-)NCBI
SpeTri2.0NW_00493648216,804,129 - 16,853,539 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDGFRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl840,967,493 - 41,021,442 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1840,966,568 - 41,021,440 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2843,067,784 - 43,081,654 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDGFRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1714,243,291 - 14,307,373 (-)NCBI
ChlSab1.1 Ensembl714,241,070 - 14,307,422 (-)Ensembl
Vero_WHO_p1.0NW_02366606615,086,695 - 15,149,115 (-)NCBI
Pdgfra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476115,223,789 - 15,269,685 (-)NCBI

Position Markers
Pdgfra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,196,275 - 75,196,396UniSTSGRCm38
MGSCv37575,592,300 - 75,592,421UniSTSGRCm37
Celera572,485,667 - 72,485,788UniSTS
Cytogenetic Map5C3.3UniSTS
cM Map542.0UniSTS
RH135893  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,197,146 - 75,197,290UniSTSGRCm38
MGSCv37575,593,171 - 75,593,315UniSTSGRCm37
Celera572,486,538 - 72,486,682UniSTS
Cytogenetic Map5C3.3UniSTS
M84607  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,195,189 - 75,195,365UniSTSGRCm38
MGSCv37575,591,214 - 75,591,390UniSTSGRCm37
Celera572,484,581 - 72,484,757UniSTS
Cytogenetic Map5C3.3UniSTS
Whitehead_YAC5 UniSTS
D5Mit201  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,154,687 - 75,154,796UniSTSGRCm38
MGSCv37575,550,712 - 75,550,821UniSTSGRCm37
Celera572,443,987 - 72,444,104UniSTS
Cytogenetic Map5C3.3UniSTS
cM Map542.0UniSTS
Whitehead Genetic528.4UniSTS
Whitehead_YAC5 UniSTS
D5Mit235  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,169,841 - 75,169,980UniSTSGRCm38
MGSCv37575,565,866 - 75,566,005UniSTSGRCm37
Celera572,459,247 - 72,459,386UniSTS
Cytogenetic Map5C3.3UniSTS
cM Map542.0UniSTS
Whitehead Genetic528.4UniSTS
Whitehead/MRC_RH51046.76UniSTS
Whitehead_YAC5 UniSTS
PMC317149P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,195,731 - 75,196,233UniSTSGRCm38
MGSCv37575,591,756 - 75,592,258UniSTSGRCm37
Celera572,485,123 - 72,485,625UniSTS
Cytogenetic Map5C3.3UniSTS
Pdgfra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38575,196,761 - 75,196,957UniSTSGRCm38
MGSCv37575,592,786 - 75,592,982UniSTSGRCm37
Celera572,486,153 - 72,486,349UniSTS
Cytogenetic Map5C3.3UniSTS
cM Map542.0UniSTS
Pdgfra  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5884069387693978Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined31975890100630065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined31975890100630065Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537424144112317856Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54442850078428622Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54616526380165263Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54616526380165263Mouse
14746981Manh57_mmandible shape 57 (mouse)54701239981012399Mouse
1300854Lmr3_mleishmaniasis resistance 3 (mouse)Not determined55253712081227149Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552537120107173175Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552537120107173175Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555230992100307666Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55230992108614761Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55548853189488652Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55612831290128312Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55816984192169980Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55945495493455133Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55945495493455133Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55945495493455133Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55945495493455133Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56009823494098356Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56025521594255313Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6250272196502841Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56250272196502841Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56250272196502841Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56250272196502841Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563548099104239199Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56422703098227149Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566381814100381814Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566381814100381814Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572271017106271152Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
10412069Desp3_mdespair 3 (mouse)Not determined57277534177098356Mouse
14700794Mencq3_mmeniscus calcification QTL 3 (mouse)57428100075687000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57515468797871944Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir34ammu-miR-34a-5pOncomiRDBexternal_infoNANA22750848
Mir34ammu-miR-34a-5pOncomiRDBexternal_infoNANA22479456
Mir219a-1mmu-miR-219a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI20223197

Predicted Target Of
Summary Value
Count of predictions:1712
Count of miRNA genes:557
Interacting mature miRNAs:649
Transcripts:ENSMUST00000000476, ENSMUST00000168162
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001083316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_144636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006504263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY628767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD354225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ099401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK627326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ912857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC424360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M57683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M84607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U47923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000000476   ⟹   ENSMUSP00000000476
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,312,967 - 75,358,876 (+)Ensembl
GRCm38.p6 Ensembl575,152,306 - 75,198,215 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168162   ⟹   ENSMUSP00000127173
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,316,560 - 75,358,862 (+)Ensembl
GRCm38.p6 Ensembl575,155,899 - 75,198,201 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200822   ⟹   ENSMUSP00000144634
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,322,495 - 75,328,598 (+)Ensembl
GRCm38.p6 Ensembl575,161,834 - 75,167,937 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201241
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,314,247 - 75,323,381 (+)Ensembl
GRCm38.p6 Ensembl575,153,586 - 75,162,720 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201711   ⟹   ENSMUSP00000143891
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,313,596 - 75,344,792 (+)Ensembl
GRCm38.p6 Ensembl575,152,935 - 75,184,131 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202161   ⟹   ENSMUSP00000144485
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,315,737 - 75,324,410 (+)Ensembl
GRCm38.p6 Ensembl575,155,076 - 75,163,749 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202186   ⟹   ENSMUSP00000144543
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,313,013 - 75,335,811 (+)Ensembl
GRCm38.p6 Ensembl575,152,352 - 75,175,150 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202681   ⟹   ENSMUSP00000143906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,312,953 - 75,344,178 (+)Ensembl
GRCm38.p6 Ensembl575,152,292 - 75,183,517 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202992   ⟹   ENSMUSP00000144132
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl575,317,494 - 75,327,221 (+)Ensembl
GRCm38.p6 Ensembl575,156,833 - 75,166,560 (+)Ensembl
RefSeq Acc Id: NM_001083316   ⟹   NP_001076785
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,316,827 - 75,358,867 (+)NCBI
GRCm38575,156,166 - 75,198,206 (+)NCBI
MGSCv37575,548,316 - 75,594,229 (+)RGD
Celera572,441,591 - 72,487,596 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001347718   ⟹   NP_001334647
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,312,912 - 75,344,792 (+)NCBI
GRCm38575,152,251 - 75,184,131 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001347719   ⟹   NP_001334648
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,313,597 - 75,344,792 (+)NCBI
GRCm38575,152,936 - 75,184,131 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011058   ⟹   NP_035188
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,312,912 - 75,358,867 (+)NCBI
GRCm38575,152,251 - 75,198,206 (+)NCBI
MGSCv37575,548,316 - 75,594,229 (+)RGD
Celera572,441,591 - 72,487,596 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_144636
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,312,912 - 75,335,811 (+)NCBI
GRCm38575,152,251 - 75,175,150 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006504261   ⟹   XP_006504324
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,313,597 - 75,358,862 (+)NCBI
GRCm38575,152,936 - 75,198,051 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006504262   ⟹   XP_006504325
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,315,548 - 75,358,862 (+)NCBI
GRCm38575,155,077 - 75,198,051 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006504263   ⟹   XP_006504326
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39575,311,988 - 75,358,862 (+)NCBI
GRCm38575,151,322 - 75,198,051 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035188   ⟸   NM_011058
- Peptide Label: isoform 1 precursor
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001076785   ⟸   NM_001083316
- Peptide Label: isoform 1 precursor
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006504326   ⟸   XM_006504263
- Peptide Label: isoform X1
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006504324   ⟸   XM_006504261
- Peptide Label: isoform X1
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006504325   ⟸   XM_006504262
- Peptide Label: isoform X1
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001334647   ⟸   NM_001347718
- Peptide Label: isoform 2 precursor
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001334648   ⟸   NM_001347719
- Peptide Label: isoform 2 precursor
- UniProtKB: P26618 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000143906   ⟸   ENSMUST00000202681
RefSeq Acc Id: ENSMUSP00000144485   ⟸   ENSMUST00000202161
RefSeq Acc Id: ENSMUSP00000144543   ⟸   ENSMUST00000202186
RefSeq Acc Id: ENSMUSP00000144132   ⟸   ENSMUST00000202992
RefSeq Acc Id: ENSMUSP00000000476   ⟸   ENSMUST00000000476
RefSeq Acc Id: ENSMUSP00000127173   ⟸   ENSMUST00000168162
RefSeq Acc Id: ENSMUSP00000143891   ⟸   ENSMUST00000201711
RefSeq Acc Id: ENSMUSP00000144634   ⟸   ENSMUST00000200822
Protein Domains
Ig-like   Ig-like C2-type   Protein kinase

Promoters
RGD ID:6886924
Promoter ID:EPDNEW_M6913
Type:initiation region
Name:Pdgfra_1
Description:Mus musculus platelet derived growth factor receptor, alpha polypeptide, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6914  EPDNEW_M6915  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38575,152,335 - 75,152,395EPDNEW
RGD ID:6886926
Promoter ID:EPDNEW_M6914
Type:multiple initiation site
Name:Pdgfra_3
Description:Mus musculus platelet derived growth factor receptor, alpha polypeptide, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6913  EPDNEW_M6915  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38575,153,600 - 75,153,660EPDNEW
RGD ID:6886928
Promoter ID:EPDNEW_M6915
Type:multiple initiation site
Name:Pdgfra_2
Description:Mus musculus platelet derived growth factor receptor, alpha polypeptide, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6913  EPDNEW_M6914  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38575,156,247 - 75,156,307EPDNEW
RGD ID:6838021
Promoter ID:MM_KWN:42603
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   ES_Cell,   Kidney,   Lung
Transcripts:NM_011058,   UC008XUA.1,   UC008XUB.1,   UC008XUD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36575,547,336 - 75,549,607 (+)MPROMDB
RGD ID:6838022
Promoter ID:MM_KWN:42605
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001083316
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36575,551,206 - 75,552,657 (+)MPROMDB
RGD ID:6838025
Promoter ID:MM_KWN:42606
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1
Transcripts:UC008XUF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36575,557,246 - 75,558,197 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97530 AgrOrtholog
Ensembl Genes ENSMUSG00000029231 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000000476 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000127173 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000143891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000143906 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144132 UniProtKB/TrEMBL
  ENSMUSP00000144485 UniProtKB/TrEMBL
  ENSMUSP00000144543 UniProtKB/TrEMBL
  ENSMUSP00000144634 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000000476 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000168162 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000200822 UniProtKB/TrEMBL
  ENSMUST00000201711 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000202161 UniProtKB/TrEMBL
  ENSMUST00000202186 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000202681 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000202992 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  PDGFRA UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_3_CS UniProtKB/Swiss-Prot
KEGG Report mmu:18595 UniProtKB/Swiss-Prot
MGD MGI:97530 ENTREZGENE
NCBI Gene 18595 ENTREZGENE
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot
PharmGKB PDGFRA RGD
PhenoGen Pdgfra PhenoGen
PIRSF Alpha-PDGF_receptor UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_III UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot
UniProt A0A0J9YUD9_MOUSE UniProtKB/TrEMBL
  A0A0J9YV49_MOUSE UniProtKB/TrEMBL
  A0A0J9YV87_MOUSE UniProtKB/TrEMBL
  A0A0J9YVF3_MOUSE UniProtKB/TrEMBL
  A0A387L9Y7_MOUSE UniProtKB/TrEMBL
  A0A387LAL0_MOUSE UniProtKB/TrEMBL
  P26618 ENTREZGENE, UniProtKB/Swiss-Prot
  Q06BS2_MOUSE UniProtKB/TrEMBL
  Q3UTU2_MOUSE UniProtKB/TrEMBL
  Q8CGH8_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TQ37 UniProtKB/Swiss-Prot
  Q62046 UniProtKB/Swiss-Prot
  Q7TSJ3 UniProtKB/Swiss-Prot
  Q8C4N3 UniProtKB/Swiss-Prot