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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response-activating cell surface receptor signaling pathway
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Accession:GO:0002429 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.
Synonyms:exact_synonym: activation of immune response by cell surface receptor signaling pathway;   immune response-activating cell surface receptor signalling pathway


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immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004624754:24,559,483...24,571,073
Ensembl chrNW_004624754:24,559,801...24,571,073
JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004624754:24,607,623...24,612,716 JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chrNW_004624746:11,660,859...11,695,991
Ensembl chrNW_004624746:11,660,426...11,695,988
JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576
JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15843560) Ensembl
MGI
TreeGrafter
PMID:15843560 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624807:7,182,094...7,192,412
Ensembl chrNW_004624807:7,183,832...7,192,320
JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:15,266,759...15,289,420
Ensembl chrNW_004624740:15,266,653...15,278,165
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) MGI PMID:23728777 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152
JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:11120811), (PMID:19228876) MGI PMID:11120811 PMID:19228876 NCBI chrNW_004624760:4,878,811...5,032,719
Ensembl chrNW_004624760:4,878,556...5,031,491
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chrNW_004624746:11,660,859...11,695,991
Ensembl chrNW_004624746:11,660,426...11,695,988
JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:23555801)
(PMID:876631)
ARUK-UCL
UniProt
PMID:876631 PMID:23555801 NCBI chrNW_004624758:25,129,922...25,180,180
Ensembl chrNW_004624758:25,129,853...25,181,761
JBrowse link
G Blnk B cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:7,565,169...7,681,102 JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624829:297,187...344,555
Ensembl chrNW_004624829:297,351...344,164
JBrowse link
G Btk Bruton tyrosine kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171
JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9254656) TreeGrafter
MGI
PMID:9254656 GO_REF:0000118 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576
JBrowse link
G Cd38 CD38 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624755:16,035,412...16,093,610
Ensembl chrNW_004624755:16,034,771...16,093,866
JBrowse link
G Cd79a CD79a molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:1373499), (PMID:8626447) InterPro
MGI
TreeGrafter
Ensembl
PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624907:803,439...806,879
Ensembl chrNW_004624907:803,359...806,897
JBrowse link
G Cd79b CD79b molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:1373499), (PMID:8626447) InterPro
MGI
TreeGrafter
PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624849:1,429,446...1,432,835
Ensembl chrNW_004624849:1,429,912...1,432,955
JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004624794:3,217,505...3,248,486 JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:5,143,239...5,219,136
Ensembl chrNW_004624801:5,143,141...5,219,244
JBrowse link
G Itk IL2 inducible T cell kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:32,125,005...32,198,901
Ensembl chrNW_004624733:32,127,388...32,198,869
JBrowse link
G Klhl6 kelch like family member 6 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624730:72,916,601...72,972,204 JBrowse link
G Lat2 linker for activation of T cells family member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:13,745,949...13,764,869 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7499277) TreeGrafter
MGI
PMID:7499277 GO_REF:0000118 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351
JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (PMID:16249387) MGI PMID:16249387 NCBI chrNW_004624741:29,390,743...29,393,457 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:23509253)
(PMID:7499277)
MGI PMID:7499277 PMID:23509253 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chrNW_004624743:8,072,871...8,235,174
Ensembl chrNW_004624743:8,072,673...8,235,252
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15143214) TreeGrafter
MGI
PMID:15143214 GO_REF:0000118 NCBI chrNW_004624752:6,298,251...6,356,562
Ensembl chrNW_004624752:6,324,181...6,357,066
JBrowse link
G Nfatc2 nuclear factor of activated T cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624790:4,366,440...4,484,279
Ensembl chrNW_004624790:4,366,406...4,484,432
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152
JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:15509800)
(MGI:1861532|PMID:10925250)
(PMID:11606584)
ARUK-UCL
UniProt
PMID:10925250 PMID:11606584 PMID:15509800 MGI:1861532 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:24,299,199...24,365,459 JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3626015|PMID:12118249) UniProt PMID:12118249 MGI:3626015 NCBI chrNW_004624782:8,974,995...9,287,609
Ensembl chrNW_004624782:8,974,765...9,287,702
JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9254656)
(PMID:23509253)
Ensembl
MGI
PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
ISO (MGI:3687418|PMID:8692271)
(PMID:9254656)
(PMID:7499277)
UniProt
MGI
PMID:7499277 PMID:8692271 PMID:9254656 MGI:3687418 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chrNW_004624821:1,561,845...1,763,654
Ensembl chrNW_004624821:1,562,778...1,751,345
JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within
ISO (PMID:9233773)
(PMID:10872802)
UniProt
MGI
PMID:9233773 PMID:10872802 NCBI chrNW_004624740:15,266,759...15,289,420
Ensembl chrNW_004624740:15,266,653...15,278,165
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO (PMID:24043312) MGI PMID:24043312 NCBI chrNW_004624738:20,466,120...20,591,966
Ensembl chrNW_004624738:20,466,117...20,591,910
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:7499277), (PMID:8626447) Ensembl
MGI
TreeGrafter
PMID:7499277 PMID:8626447 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391
JBrowse link
G Tec tec protein tyrosine kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624761:18,695,168...18,824,045
Ensembl chrNW_004624761:18,695,177...18,822,078
JBrowse link
G Txk TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,841,795...18,897,564
Ensembl chrNW_004624761:18,841,795...18,897,458
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004624772:3,604,553...4,022,986
Ensembl chrNW_004624772:3,604,165...4,022,990
JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) AgBase PMID:15294986 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910
JBrowse link
G Fcn1 ficolin 1 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004624760:2,743,996...2,751,116
Ensembl chrNW_004624760:2,743,996...2,751,110
JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004624794:8,140,629...8,155,313
Ensembl chrNW_004624794:8,140,629...8,155,258
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:15294986) AgBase PMID:15294986 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) ComplexPortal PMID:22966085 NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297
JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624860:5,196,621...5,204,686
Ensembl chrNW_004624860:5,197,619...5,199,043
JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394
JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624832:6,403,002...6,411,399
Ensembl chrNW_004624832:6,403,621...6,404,631
JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:6189359|PMID:22632727) ARUK-UCL PMID:22632727 MGI:6189359 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946
JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624860:5,196,621...5,204,686
Ensembl chrNW_004624860:5,197,619...5,199,043
JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394
JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:6,403,002...6,411,399
Ensembl chrNW_004624832:6,403,621...6,404,631
JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:11,553,268...11,601,105 JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624765:9,898,536...9,953,815
Ensembl chrNW_004624765:9,952,440...9,953,507
JBrowse link
G Fpr1 formyl peptide receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,305,274...3,309,964
Ensembl chrNW_004624832:3,308,802...3,309,845
JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,275,365...3,282,308 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chrNW_004624756:2,505,937...2,569,618
Ensembl chrNW_004624756:2,505,945...2,569,464
JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:6189359|PMID:22632727) ARUK-UCL PMID:22632727 MGI:6189359 NCBI chrNW_004624782:14,316,505...14,367,841
Ensembl chrNW_004624782:14,318,499...14,367,922
JBrowse link
G LOC101706116 N-formyl peptide receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,238,627...3,239,711
Ensembl chrNW_004624832:3,238,627...3,239,685
JBrowse link
G LOC106007553 N-formyl peptide receptor 2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,255,571...3,262,458 JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myo1g myosin IG involved_in ISO (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792 NCBI chrNW_004624740:7,362,653...7,374,041
Ensembl chrNW_004624740:7,363,143...7,373,713
JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chrNW_004624788:15,158,920...15,294,785 JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624794:8,211,232...8,224,020
Ensembl chrNW_004624794:8,211,094...8,221,866
JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004624794:3,217,505...3,248,486 JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004624786:9,938,384...9,941,210
Ensembl chrNW_004624786:9,938,384...9,941,235
JBrowse link
G Lpxn leupaxin involved_in ISO (MGI:3722965|PMID:17640867)
(PMID:17640867)
UniProt PMID:17640867 MGI:3722965 NCBI chrNW_004624864:1,815,056...1,852,041
Ensembl chrNW_004624864:1,818,614...1,852,503
JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within ISO (PMID:14517301) MGI PMID:14517301 NCBI chrNW_004624821:2,132,075...2,316,624
Ensembl chrNW_004624821:2,131,851...2,315,934
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308
JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004624831:868,417...1,065,591
Ensembl chrNW_004624831:868,563...1,060,248
JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004624731:43,803,743...44,018,682
Ensembl chrNW_004624731:43,803,768...44,015,870
JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chrNW_004624767:2,173,774...2,210,304
Ensembl chrNW_004624767:2,173,272...2,210,279
JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in
ISO (PMID:24714587)
(PMID:38225265)
MGI
UniProt
PMID:24714587 PMID:38225265 NCBI chrNW_004624756:23,968,148...24,017,340
Ensembl chrNW_004624756:23,968,017...24,017,332
JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:994,103...1,001,697 JBrowse link
G Elf1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14738763) Ensembl
MGI
PMID:14738763 GO_REF:0000107 NCBI chrNW_004624748:13,987,001...14,090,451
Ensembl chrNW_004624748:14,017,621...14,091,619
JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004624929:827,275...873,743
Ensembl chrNW_004624929:826,531...873,572
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135
JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637
JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (PMID:12970181) MGI PMID:12970181 NCBI chrNW_004624750:18,562,270...18,710,397
Ensembl chrNW_004624750:18,562,221...18,705,540
JBrowse link
G Prnp prion protein (Kanno blood group) involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chrNW_004624741:5,785,139...5,802,162
Ensembl chrNW_004624741:5,785,158...5,802,162
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chrNW_004624770:19,808,400...19,877,494
Ensembl chrNW_004624770:19,808,400...19,876,503
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990
JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9064344) Ensembl
MGI
PMID:9064344 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090
JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:11259588), (PMID:9780142)
(MGI:4942249|PMID:12913111)
(PMID:12913111)
UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chrNW_004624767:942,786...1,051,112
Ensembl chrNW_004624767:945,553...1,051,138
JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chrNW_004624797:3,120,123...3,142,564
Ensembl chrNW_004624797:3,120,123...3,142,564
JBrowse link
G Sla2 Src like adaptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624842:2,853,183...2,882,269
Ensembl chrNW_004624842:2,853,144...2,881,116
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chrNW_004624784:14,779,533...14,784,315
Ensembl chrNW_004624784:14,780,698...14,784,897
JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14738763) TreeGrafter
MGI
PMID:14738763 GO_REF:0000118 NCBI chrNW_004624745:28,026,274...28,057,922 JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chrNW_004624751:23,478,263...23,488,834
Ensembl chrNW_004624751:23,478,096...23,483,521
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:4456928|PMID:20385881) UniProt PMID:20385881 MGI:4456928 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6162316|PMID:26599367)
(PMID:26599367)
UniProt PMID:26599367 MGI:6162316 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) ARUK-UCL PMID:31134514 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231
JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chrNW_004624751:23,478,263...23,488,834
Ensembl chrNW_004624751:23,478,096...23,483,521
JBrowse link
G Bpifb1 BPI fold containing family B member 1 involved_in ISO (PMID:21900486) UniProt PMID:21900486 NCBI chrNW_004624842:5,951,202...5,972,212
Ensembl chrNW_004624842:5,951,203...5,972,212
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:19948740) UniProt PMID:19948740 NCBI chrNW_004624760:13,472,500...13,658,070
Ensembl chrNW_004624760:13,472,672...13,657,930
JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:4456928|PMID:20385881) UniProt PMID:20385881 MGI:4456928 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677
JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:3,102,424...3,109,497
Ensembl chrNW_004624795:3,102,439...3,109,497
JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (MGI:3834524|PMID:17395780) UniProt PMID:17395780 MGI:3834524 NCBI chrNW_004624807:5,307,361...5,334,578
Ensembl chrNW_004624807:5,307,440...5,334,945
JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) UniProt PMID:31281713 NCBI chrNW_004624733:42,689,454...42,700,916
Ensembl chrNW_004624733:42,691,841...42,700,916
JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004624739:2,800,453...2,894,355
Ensembl chrNW_004624739:2,801,301...2,885,094
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6152919|PMID:29407460)
(MGI:6695864|PMID:31134514)
ARUK-UCL PMID:29407460 PMID:31134514 MGI:6152919 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231
JBrowse link
G Trim32 tripartite motif containing 32 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004624760:18,577,764...18,600,869
Ensembl chrNW_004624760:18,585,279...18,599,659
JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922
JBrowse link
G Cmtm3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chrNW_004624746:19,830,839...19,840,350
Ensembl chrNW_004624746:19,830,839...19,839,430
JBrowse link
G Foxp1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624752:6,298,251...6,356,562
Ensembl chrNW_004624752:6,324,181...6,357,066
JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chrNW_004624782:8,974,995...9,287,609
Ensembl chrNW_004624782:8,974,765...9,287,702
JBrowse link
G Prkch protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:39,620,690...39,830,281
Ensembl chrNW_004624734:39,619,273...39,830,353
JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (PMID:25074919) MGI PMID:25074919 NCBI chrNW_004624854:1,163,025...1,280,717 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:1,361,271...1,409,548
Ensembl chrNW_004624761:1,361,498...1,409,674
JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004624767:942,786...1,051,112
Ensembl chrNW_004624767:945,553...1,051,138
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004624772:7,340,152...7,425,218
Ensembl chrNW_004624772:7,368,653...7,424,938
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004624760:4,376,733...4,474,834
Ensembl chrNW_004624760:4,376,713...4,474,837
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079
JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chrNW_004624825:1,098,915...1,141,373
Ensembl chrNW_004624825:1,097,432...1,141,446
JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883
JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759
JBrowse link
G Card11 caspase recruitment domain family member 11 involved_in ISO (MGI:6695669|PMID:12154356)
(PMID:12154360)
UniProt PMID:12154356 PMID:12154360 MGI:6695669 NCBI chrNW_004624740:29,974,707...30,085,498
Ensembl chrNW_004624740:29,974,689...30,085,981
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:2,777,766...2,787,664
Ensembl chrNW_004624795:2,779,627...2,788,897
JBrowse link
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206
JBrowse link
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (PMID:16501569) MGI PMID:16501569 NCBI chrNW_004624757:5,895,912...5,953,485 JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699
JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:19179613) MGI PMID:19179613 NCBI chrNW_004624737:49,471...82,981
Ensembl chrNW_004624737:49,371...83,514
JBrowse link
G LOC101706523 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chrNW_004624731:40,281,086...40,319,254
Ensembl chrNW_004624731:40,280,884...40,306,653
JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627
JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chrNW_004624832:6,885,627...6,915,316
Ensembl chrNW_004624832:6,886,327...6,915,179
JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chrNW_004624807:5,478,570...5,483,473
Ensembl chrNW_004624807:5,478,707...5,483,475
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
JBrowse link
G Rps3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624817:1,710,768...1,715,923
Ensembl chrNW_004624817:1,710,768...1,716,224
JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624983:31,552...47,575
Ensembl chrNW_004624983:31,766...45,077
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004624754:16,701,950...16,798,293
Ensembl chrNW_004624754:16,701,331...16,798,897
JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G LOC101717043 cytochrome b-245 light chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chrNW_004624746:911,852...919,361
Ensembl chrNW_004624746:911,842...919,362
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6162316|PMID:26599367)
(PMID:26599367), (PMID:28471450)
UniProt PMID:26599367 PMID:28471450 MGI:6162316 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:27,251,937...27,331,213
Ensembl chrNW_004624743:27,254,436...27,301,934
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004624840:7,287,772...7,349,282
Ensembl chrNW_004624840:7,287,781...7,290,162
JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (MGI:5645195|PMID:24380872) UniProt PMID:24380872 MGI:5645195 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) UniProt PMID:18622013 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Ifi35 interferon induced protein 35 involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004624795:1,260,476...1,268,015
Ensembl chrNW_004624795:1,260,476...1,262,080
JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:11528597) BHF-UCL PMID:11528597 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)
UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886
JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6694429|PMID:25860173) UniProt PMID:25860173 MGI:6694429 NCBI chrNW_004624868:3,430,539...3,442,205
Ensembl chrNW_004624868:3,430,209...3,445,542
JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004624767:1,459,601...1,473,224
Ensembl chrNW_004624767:1,459,601...1,467,795
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004624762:9,328,275...9,382,996
Ensembl chrNW_004624762:9,328,109...9,386,067
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:1,353,601...1,405,762
Ensembl chrNW_004624823:1,353,621...1,401,160
JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chrNW_004624746:11,847,627...11,954,637
Ensembl chrNW_004624746:11,848,425...11,954,784
JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (MGI:1100180|PMID:9382888)
(PMID:9382888)
UniProt PMID:9382888 MGI:1100180 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576
JBrowse link
G Fcmr Fc mu receptor involved_in ISO (MGI:5888941|PMID:28135254) UniProt PMID:28135254 MGI:5888941 NCBI chrNW_004624807:4,567,240...4,581,406 JBrowse link
G Gcsam germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chrNW_004624731:36,444,290...36,451,195 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase involved_in ISO
IEA
RGD
TreeGrafter
PMID:9325302 GO_REF:0000118 RGD:2303720 NCBI chrNW_004624894:12,621...29,400
Ensembl chrNW_004624894:24,203...29,668
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chrNW_004624826:23,930...34,735 JBrowse link
G Pten phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:15235600)
(PMID:17341663)
MGI PMID:15235600 PMID:17341663 NCBI chrNW_004624740:8,624,231...8,688,747
Ensembl chrNW_004624740:8,624,205...8,690,800
JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759
JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351
JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in
acts_upstream_of
IEA
ISO
(PMID:28598420) Ensembl
MGI
PMID:28598420 GO_REF:0000107 NCBI chrNW_004624983:31,552...47,575
Ensembl chrNW_004624983:31,766...45,077
JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079
JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624754:24,992,961...25,000,463
Ensembl chrNW_004624754:24,992,929...25,003,759
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624815:1,290,106...1,376,961
Ensembl chrNW_004624815:1,289,997...1,369,610
JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) ARUK-UCL PMID:31134514 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231
JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910
JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900) ARUK-UCL PMID:19136564 PMID:22041900 MGI:3844414 MGI:5300086 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391
JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244
JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244
JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004624760:4,878,811...5,032,719
Ensembl chrNW_004624760:4,878,556...5,031,491
JBrowse link
G Ada adenosine deaminase acts_upstream_of ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883
JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759
JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624829:297,187...344,555
Ensembl chrNW_004624829:297,351...344,164
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) MGI PMID:18228248 NCBI chrNW_004624765:20,766,368...20,951,560
Ensembl chrNW_004624765:20,773,885...20,951,736
JBrowse link
G Btk Bruton tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171
JBrowse link
G Btn1a1 butyrophilin subfamily 1 member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624756:356,124...362,425
Ensembl chrNW_004624756:357,047...362,415
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (PMID:17028169) MGI PMID:17028169 NCBI chrNW_004624816:3,334,934...3,348,355
Ensembl chrNW_004624816:3,334,684...3,347,842
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (PMID:15637280), (PMID:17028169) MGI PMID:15637280 PMID:17028169 NCBI chrNW_004624866:4,973,087...5,287,477
Ensembl chrNW_004624866:4,973,207...5,281,746
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004624746:18,692,179...18,704,952
Ensembl chrNW_004624746:18,692,225...18,704,476
JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:12697763) MGI PMID:12697763 NCBI chrNW_004624731:43,803,743...44,018,682
Ensembl chrNW_004624731:43,803,768...44,015,870
JBrowse link
G Cd247 CD247 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11435465) TreeGrafter
MGI
PMID:11435465 GO_REF:0000118 NCBI chrNW_004624826:5,504,676...5,574,037
Ensembl chrNW_004624826:5,505,569...5,573,783
JBrowse link
G Cd276 CD276 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624781:691,348...703,202 JBrowse link
G Cd28 CD28 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23793062) TreeGrafter
MGI
PMID:23793062 GO_REF:0000118 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd2ap CD2 associated protein acts_upstream_of_or_within ISO (PMID:14512504) MGI PMID:14512504 NCBI chrNW_004624754:13,420,594...13,511,672
Ensembl chrNW_004624754:13,420,603...13,511,523
JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:10485657) MGI PMID:10485657 NCBI chrNW_004624784:13,714,667...13,726,881
Ensembl chrNW_004624784:13,712,920...13,726,950
JBrowse link
G Cd8a CD8 subunit alpha involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004624749:16,564,944...16,569,890 JBrowse link
G Cd8b CD8 subunit beta involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004624749:16,513,360...16,525,494 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004624945:734,532...767,184
Ensembl chrNW_004624945:734,532...767,168
JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)
UniProt PMID:26774822 MGI:5751612 NCBI chrNW_004624798:2,621,604...2,844,370
Ensembl chrNW_004624798:2,622,379...2,838,775
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624747:23,413,045...23,422,227
Ensembl chrNW_004624747:23,414,077...23,421,074
JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:26,682,521...26,688,490
Ensembl chrNW_004624734:26,682,521...26,688,559
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624906:733,148...882,690
Ensembl chrNW_004624906:733,146...892,362
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624738:9,438,484...9,443,931
Ensembl chrNW_004624738:9,437,554...9,443,747
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624730:72,417,069...72,428,194
Ensembl chrNW_004624730:72,417,856...72,428,093
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in ISO (PMID:32098969) UniProt PMID:32098969 NCBI chrNW_004624908:1,327,569...1,340,741
Ensembl chrNW_004624908:1,327,602...1,340,240
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:32610127) MGI PMID:32610127 NCBI chrNW_004624738:10,370,479...10,391,623
Ensembl chrNW_004624738:10,370,103...10,391,623
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:10072494), (PMID:11265635) MGI PMID:10072494 PMID:11265635 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Fyb1 FYN binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624759:15,683,741...15,794,628
Ensembl chrNW_004624759:15,683,779...15,793,908
JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chrNW_004624862:3,323,643...3,463,825 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624933:248,298...456,933
Ensembl chrNW_004624933:389,627...456,520
JBrowse link
G Gata3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392
JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21444916) Ensembl
MGI
PMID:21444916 GO_REF:0000107 NCBI chrNW_004624766:21,907,423...21,913,414
Ensembl chrNW_004624766:21,911,241...21,913,653
JBrowse link
G Icoslg inducible T cell costimulator ligand involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:29,880,943...29,888,635
Ensembl chrNW_004624745:29,880,992...29,888,717
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
G Itk IL2 inducible T cell kinase involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624733:32,125,005...32,198,901
Ensembl chrNW_004624733:32,127,388...32,198,869
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:15,244,521...15,292,901
Ensembl chrNW_004624764:15,244,390...15,275,379
JBrowse link
G Lat linker for activation of T cells involved_in ISO (PMID:25907557) UniProt PMID:25907557 NCBI chrNW_004624782:12,795,104...12,799,496
Ensembl chrNW_004624782:12,795,104...12,799,410
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:8943371) UniProt PMID:8943371 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004624733:19,625,276...19,720,125
Ensembl chrNW_004624733:19,672,868...19,719,584
JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663
JBrowse link
G LOC101698274 V-set domain-containing T-cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624731:27,867,562...27,900,768 JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713
JBrowse link
G LOC101716577 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within
ISO (PMID:9489702)
(PMID:9208839)
UniProt
MGI
PMID:9208839 PMID:9489702 NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035
JBrowse link
G LOC106008672 butyrophilin-like protein 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624958:519,966...591,348 JBrowse link
G Malt1 MALT1 paracaspase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757
JBrowse link
G Mog myelin oligodendrocyte glycoprotein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:25,397,191...25,412,123
Ensembl chrNW_004624754:25,397,144...25,411,319
JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624794:10,172,789...10,180,693
Ensembl chrNW_004624794:10,168,792...10,179,510
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152
JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004624772:10,358,554...10,369,371 JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004624742:28,557,159...29,113,269
Ensembl chrNW_004624742:28,557,283...29,016,844
JBrowse link
G Plcg1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004624919:1,766,533...1,800,130
Ensembl chrNW_004624919:1,766,149...1,803,097
JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855
JBrowse link
G Pram1 PML-RARA regulated adaptor molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:1,251,566...1,259,032
Ensembl chrNW_004624828:1,251,815...1,256,314
JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chrNW_004624832:6,885,627...6,915,316
Ensembl chrNW_004624832:6,886,327...6,915,179
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004624734:28,200,358...28,272,684
Ensembl chrNW_004624734:28,200,140...28,272,743
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004624771:17,183,538...17,205,460
Ensembl chrNW_004624771:17,183,447...17,224,188
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14752163) Ensembl
MGI
TreeGrafter
PMID:14752163 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990
JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of
IEA
ISO
(PMID:9064344) Ensembl
MGI
PMID:9064344 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090
JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004624741:1,503,017...1,523,542
Ensembl chrNW_004624741:1,502,942...1,523,675
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:12,025,206...12,074,548 JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chrNW_004624821:1,561,845...1,763,654
Ensembl chrNW_004624821:1,562,778...1,751,345
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
ISO (MGI:5285496|PMID:21469090)
(PMID:11894098)
UniProt
MGI
PMID:11894098 PMID:21469090 MGI:5285496 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890
JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004624820:8,376,530...8,388,596
Ensembl chrNW_004624820:8,375,871...8,388,569
JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:24645804) MGI PMID:24645804 NCBI chrNW_004624825:3,846,604...3,972,780
Ensembl chrNW_004624825:3,845,092...3,973,636
JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chrNW_004624795:4,726,715...4,960,167
Ensembl chrNW_004624795:4,727,149...4,960,082
JBrowse link
G Slc39a6 solute carrier family 39 member 6 involved_in ISO (PMID:34394081) UniProt PMID:34394081 NCBI chrNW_004624779:10,400,581...10,433,405
Ensembl chrNW_004624779:10,399,198...10,432,869
JBrowse link
G Spn sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chrNW_004624782:13,471,083...13,483,712 JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971)
(MGI:5640905|PMID:25384971)
UniProt PMID:25384971 MGI:5640905 NCBI chrNW_004624747:12,795,803...12,925,319
Ensembl chrNW_004624747:12,795,563...12,928,649
JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (PMID:21487392) MGI PMID:21487392 NCBI chrNW_004624828:7,444,339...7,466,926
Ensembl chrNW_004624828:7,445,069...7,467,298
JBrowse link
G Stoml2 stomatin like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18641330) Ensembl
UniProt
PMID:18641330 GO_REF:0000107 NCBI chrNW_004624915:294,781...298,312
Ensembl chrNW_004624915:294,777...298,278
JBrowse link
G Tec tec protein tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,695,168...18,824,045
Ensembl chrNW_004624761:18,695,177...18,822,078
JBrowse link
G Themis thymocyte selection associated involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624753:2,214,779...2,292,936 JBrowse link
G Themis2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22732588) TreeGrafter
MGI
PMID:22732588 GO_REF:0000118 NCBI chrNW_004624764:11,717,083...11,732,791
Ensembl chrNW_004624764:11,717,950...11,732,799
JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:14,779,533...14,784,315
Ensembl chrNW_004624784:14,780,698...14,784,897
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chrNW_004624754:13,567,898...13,633,368
Ensembl chrNW_004624754:13,567,734...13,634,009
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:23514740)
(PMID:15125833)
UniProt PMID:15125833 PMID:23514740 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455
JBrowse link
G Txk TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,841,795...18,897,564
Ensembl chrNW_004624761:18,841,795...18,897,458
JBrowse link
G Ube2n ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624750:13,432,657...13,468,797
Ensembl chrNW_004624750:13,432,661...13,457,776
JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:12,837,940...12,911,263
Ensembl chrNW_004624772:12,837,668...12,911,802
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chrNW_004624735:8,987,390...9,122,277
Ensembl chrNW_004624735:8,987,469...9,124,516
JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629
JBrowse link
G Znf683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chrNW_004624764:10,382,733...10,388,608 JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) BHF-UCL PMID:11544529 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10383454)
(PMID:10549626)
BHF-UCL
MGI
PMID:10383454 PMID:10549626 NCBI chrNW_004624946:613,392...618,459
Ensembl chrNW_004624946:613,890...618,445
JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890
JBrowse link
G Tlr2 toll like receptor 2 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chrNW_004624755:24,976,375...24,995,150
Ensembl chrNW_004624755:24,976,361...25,001,397
JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO (PMID:26189595) UniProt PMID:26189595 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131
JBrowse link
G Ecsit ECSIT signaling integrator involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624828:3,264,054...3,276,270
Ensembl chrNW_004624828:3,264,149...3,269,030
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184
JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chrNW_004624946:613,392...618,459
Ensembl chrNW_004624946:613,890...618,445
JBrowse link
G Irak2 interleukin 1 receptor associated kinase 2 involved_in ISO (PMID:17878161) UniProt PMID:17878161 NCBI chrNW_004624731:5,294,464...5,348,426
Ensembl chrNW_004624731:5,294,431...5,348,481
JBrowse link
G Irf3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:4,611,445...4,616,319
Ensembl chrNW_004624832:4,612,374...4,616,276
JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ly96 lymphocyte antigen 96 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624744:17,209,285...17,241,347
Ensembl chrNW_004624744:17,208,990...17,241,347
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624799:3,554,644...3,623,317
Ensembl chrNW_004624799:3,554,678...3,622,289
JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:29624734) MGI PMID:29624734 NCBI chrNW_004624795:1,553,582...1,558,110
Ensembl chrNW_004624795:1,553,037...1,558,197
JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:18261938) Ensembl
MGI
TreeGrafter
PMID:18261938 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205
JBrowse link
G Nmi N-myc and STAT interactor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624866:4,230,258...4,263,156
Ensembl chrNW_004624866:4,229,535...4,263,688
JBrowse link
G Oas1 2'-5'-oligoadenylate synthetase 1 involved_in ISO (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chrNW_004624747:19,428,994...19,434,512
Ensembl chrNW_004624747:19,428,833...19,434,550
JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890
JBrowse link
G S100a14 S100 calcium binding protein A14 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624885:3,529,813...3,531,314
Ensembl chrNW_004624885:3,529,026...3,532,182
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986
JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:28747347) UniProt PMID:28747347 NCBI chrNW_004624802:3,861,821...3,914,061
Ensembl chrNW_004624802:3,862,709...3,914,028
JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25549946) Ensembl
MGI
TreeGrafter
PMID:25549946 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link
G Tmem126a transmembrane protein 126A acts_upstream_of_or_within ISO (PMID:25549946) MGI PMID:25549946 NCBI chrNW_004624845:4,264,497...4,272,973 JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) UniProt PMID:17088249 NCBI chrNW_004624777:1,124,389...1,222,450
Ensembl chrNW_004624777:1,124,204...1,158,324
JBrowse link
G Traf3 TNF receptor associated factor 3 involved_in ISO (PMID:18222170) UniProt PMID:18222170 NCBI chrNW_004624734:1,728,353...1,820,345
Ensembl chrNW_004624734:1,728,255...1,786,010
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455
JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004624739:1,663,916...1,668,258
Ensembl chrNW_004624739:1,664,432...1,666,867
JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646
JBrowse link
G Tlr5 toll like receptor 5 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chrNW_004624835:5,495,723...5,503,462
Ensembl chrNW_004624835:5,500,461...5,503,034
JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)
UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Prkce protein kinase C epsilon involved_in ISO (MGI:3652658|PMID:16757566) UniProt PMID:16757566 MGI:3652658 NCBI chrNW_004624738:27,118,764...27,630,733
Ensembl chrNW_004624738:27,118,145...27,627,606
JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO (PMID:30883606) UniProt PMID:30883606 NCBI chrNW_004624737:28,633,815...28,675,773
Ensembl chrNW_004624737:28,634,079...28,686,886
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      activation of immune response 460
        immune response-activating signaling pathway 405
          immune response-activating cell surface receptor signaling pathway 247
            Fc receptor mediated stimulatory signaling pathway + 15
            antigen receptor-mediated signaling pathway + 159
            complement receptor mediated signaling pathway + 12
            innate immune response activating cell surface receptor signaling pathway + 73
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10618
      regulation of biological process 10301
        regulation of immune system process 1351
          positive regulation of immune system process 948
            positive regulation of immune response 617
              activation of immune response 460
                immune response-activating signaling pathway 405
                  immune response-activating cell surface receptor signaling pathway 247
                    Fc receptor mediated stimulatory signaling pathway + 15
                    antigen receptor-mediated signaling pathway + 159
                    complement receptor mediated signaling pathway + 12
                    innate immune response activating cell surface receptor signaling pathway + 73
paths to the root