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ONTOLOGY REPORT - ANNOTATIONS


Term:innate immune response activating cell surface receptor signaling pathway
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Accession:GO:0002220 term browser browse the term
Definition:Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor.
Synonyms:exact_synonym: activation of innate immune response by cell surface receptor signaling pathway;   innate immune response activating cell surface receptor signalling pathway



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cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) RGD PMID:12719478 MGI:3042099 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Fcna ficolin A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105
JBrowse link
G Fcnb ficolin B involved_in ISO (PMID:21037097) RGD PMID:21037097 NCBI chr 3:11,393,771...11,402,198
Ensembl chr 3:11,393,739...11,402,151
JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO
ISS
(PMID:21037097)
GO_REF:0000024
RGD
UniProt
PMID:21037097 GO_REF:0000024 NCBI chr 1:86,071,860...86,075,049
Ensembl chr 1:86,072,184...86,075,033
JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (MGI:3042099|PMID:12719478) RGD PMID:12719478 MGI:3042099 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4a C-type lectin domain family 4, member A involved_in ISO (MGI:5300086|PMID:22041900) RGD PMID:22041900 MGI:5300086 NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
JBrowse link
G Clec4n C-type lectin domain family 4, member n involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 4:156,539,408...156,558,605 JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:9655483) RGD PMID:9655483 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
ISS
(PMID:9655483)
GO_REF:0000024
RGD
UniProt
PMID:9655483 GO_REF:0000024 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:163,032,938...163,041,641
Ensembl chr 4:163,033,563...163,041,638
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2450811|PMID:12645935)
Ensembl
RGD
PMID:12645935 GO_REF:0000107 MGI:2450811 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in ISO
IEA
(MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900)
GO_REF:0000107
RGD
Ensembl
PMID:19136564 PMID:22041900 GO_REF:0000107 MGI:3844414 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA
(MGI:3844414|PMID:19136564)
GO_REF:0000107
RGD
Ensembl
PMID:19136564 GO_REF:0000107 MGI:3844414 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
ISS
(PMID:9655483)
GO_REF:0000024
RGD
UniProt
PMID:9655483 GO_REF:0000024 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISS
ISO
GO_REF:0000024
(PMID:9655483)
UniProt
RGD
PMID:9655483 GO_REF:0000024 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    immune system process 2787
      activation of immune response 397
        immune response-activating signal transduction 316
          immune response-activating cell surface receptor signaling pathway 315
            innate immune response activating cell surface receptor signaling pathway 14
              cell surface pattern recognition receptor signaling pathway 5
              stimulatory C-type lectin receptor signaling pathway 10
              stimulatory killer cell immunoglobulin-like receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 19390
    response to stimulus 10323
      response to biotic stimulus 1724
        response to external biotic stimulus 1685
          response to other organism 1681
            defense response to other organism 1091
              innate immune response 806
                regulation of innate immune response 202
                  positive regulation of innate immune response 124
                    activation of innate immune response 42
                      innate immune response-activating signal transduction 15
                        innate immune response activating cell surface receptor signaling pathway 14
                          cell surface pattern recognition receptor signaling pathway 5
                          stimulatory C-type lectin receptor signaling pathway 10
                          stimulatory killer cell immunoglobulin-like receptor signaling pathway 1
paths to the root