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ONTOLOGY REPORT - ANNOTATIONS

Term:signal transduction in response to DNA damage
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Accession:GO:0042770 term browser browse the term
Definition:A cascade of processes induced by the detection of DNA damage within a cell.
Synonyms:exact_synonym: DNA damage response, signal transduction;   response to DNA damage stimulus by intracellular signaling cascade
 narrow_synonym: DNA damage induced protein phosphorylation
 alt_id: GO:0006975


show annotations for term's descendants           Sort by:
signal transduction in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:15657060), (PMID:18280240), (PMID:9037071) RGD PMID:9037071 PMID:15657060 PMID:18280240 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:15983387) RGD PMID:15983387 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:26774286), (PMID:27664052) RGD PMID:26774286 PMID:27664052 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:15657060) RGD PMID:15657060 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cep63 centrosomal protein 63 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in IMP
ISO		 (PMID:16963448) RGD PMID:16963448 PMID:11278490 RGD:2316109 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:14744935)
(PMID:11298456)		 RGD PMID:11298456 PMID:14744935 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISO
ISS		 (MGI:5567851|PMID:24489120)
GO_REF:0000024		 RGD
UniProt		 PMID:24489120 GO_REF:0000024 MGI:5567851 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:20160708)		 Ensembl
RGD		 PMID:20160708 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO (PMID:20160708) RGD PMID:20160708 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:17560175) RGD PMID:17560175 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (MGI:3835231|PMID:19015238) RGD PMID:19015238 MGI:3835231 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO (PMID:16501043) RGD PMID:16501043 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:30886146)
(PMID:12937170)
GO_REF:0000033		 RGD
GO_Central		 PMID:12937170 PMID:30886146 GO_REF:0000033 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:14657349), (PMID:21705319), (PMID:21777809)
(PMID:12937170)
GO_REF:0000033		 RGD
GO_Central		 PMID:12937170 PMID:14657349 PMID:21705319 PMID:21777809 GO_REF:0000033 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Atrip ATR interacting protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:109,708,440...109,722,511
Ensembl chr 8:109,708,440...109,722,477 		JBrowse link
G Cdc5l cell division cycle 5-like involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24332808)		 UniProt
Ensembl
RGD		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Cep63 centrosomal protein 63 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:16963448), (PMID:19716789)
MGI:1926528 (PMID:10859164), (PMID:12529385)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:10859164 PMID:12529385 PMID:16963448 PMID:19716789 GO_REF:0000002 GO_REF:0000024 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:10435585 RGD:633752 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Clock clock circadian regulator involved_in ISO
IEA		 (PMID:21659603)
GO_REF:0000107		 RGD
Ensembl		 PMID:21659603 GO_REF:0000107 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Clspn claspin involved_in ISO (PMID:16963448) RGD PMID:16963448 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:12717439)		 UniProt
Ensembl
RGD		 PMID:12717439 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor involved_in ISO (PMID:25820262) RGD PMID:25820262 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Gnb1l G protein subunit beta 1 like involved_in ISO (PMID:37541219) RGD PMID:37541219 NCBI chr11:82,425,301...82,507,836
Ensembl chr11:82,432,627...82,507,466 		JBrowse link
G H2ax H2A.X variant histone involved_in
NOT|acts_upstream_of_or_within		 ISO (PMID:17974976)
MGI:2156048 (PMID:11934988)		 RGD PMID:11934988 PMID:17974976 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hinfp histone H4 transcription factor involved_in ISO (PMID:17974976) RGD PMID:17974976 NCBI chr 8:44,634,333...44,644,288
Ensembl chr 8:44,634,333...44,641,000 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in
acts_upstream_of_or_within		 ISO (PMID:21659603)
MGI:1927769 (PMID:12529385)		 RGD PMID:12529385 PMID:21659603 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Ints7 integrator complex subunit 7 involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO		 GO_REF:0000107
(PMID:10891478)		 Ensembl
RGD		 PMID:10891478 GO_REF:0000107 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:11836244) RGD PMID:11836244 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12937170)		 Ensembl
RGD		 PMID:12937170 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Nbn nibrin acts_upstream_of_or_within ISO (PMID:12529385) RGD PMID:12529385 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:28525742) RGD PMID:28525742 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24332808)		 UniProt
Ensembl
RGD		 PMID:24332808 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176524 (PMID:12937170)		 Ensembl
RGD		 PMID:12937170 GO_REF:0000107 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease involved_in ISO
IBA		 (PMID:21659603)
GO_REF:0000033		 RGD
GO_Central		 PMID:21659603 GO_REF:0000033 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in ISO (PMID:21659603) RGD PMID:21659603 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372 		JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 involved_in IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
(PMID:21659603), (PMID:25602520)		 InterPro
TreeGrafter
GO_Central
RGD		 PMID:21659603 PMID:25602520 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:161,634,047...161,639,437
Ensembl chr 4:161,634,048...161,639,371 		JBrowse link
G Rhno1-ps2 RAD9-HUS1-RAD1 interacting nuclear orphan 1, pseudogene 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:184,691,837...184,692,934
Ensembl chr 2:184,691,839...184,692,926
Ensembl chr 2:184,691,839...184,692,926 		JBrowse link
G Stk38 serine/threonine kinase 38 involved_in ISO (PMID:32537488) RGD PMID:32537488 NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198 		JBrowse link
G Tipin timeless interacting protein acts_upstream_of_or_within ISO (PMID:17141802) RGD PMID:17141802 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Tiprl TOR signaling pathway regulator involved_in ISO
IEA		 (PMID:17384681)
GO_REF:0000107		 RGD
Ensembl		 PMID:17384681 GO_REF:0000107 NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:17575048), (PMID:21777809), (PMID:31135337) RGD PMID:17575048 PMID:21777809 PMID:31135337 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:18045533) RGD PMID:18045533 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30886146)		 UniProt
RGD		 PMID:30886146 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(PMID:18662541)		 UniProt
GO_Central
TreeGrafter
RGD		 PMID:18662541 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229 		JBrowse link
DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:28294157), (PMID:29229990) RGD PMID:28294157 PMID:29229990 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Atrx ATRX, chromatin remodeler involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5568153|PMID:24651726)		 UniProt
Ensembl
RGD		 PMID:24651726 GO_REF:0000024 GO_REF:0000107 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448499|PMID:22385964)		 UniProt
RGD		 PMID:22385964 GO_REF:0000024 MGI:5448499 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO (PMID:15383658) RGD PMID:15383658 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO
IEA		 (PMID:14660608)
GO_REF:0000107		 RGD
Ensembl		 PMID:14660608 GO_REF:0000107 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mif macrophage migration inhibitory factor acts_upstream_of_or_within ISO MGI:2673280 (PMID:12878730) RGD PMID:12878730 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:16507995) RGD PMID:16507995 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO
IEA		 (PMID:9766676)
GO_REF:0000107		 RGD
Ensembl		 PMID:9766676 GO_REF:0000107 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 acts_upstream_of_or_within ISO (PMID:33323934) RGD PMID:33323934 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:15456759), (PMID:17690115) RGD PMID:15456759 PMID:17690115 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D acts_upstream_of_or_within ISO (PMID:21522133) RGD PMID:21522133 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:18692468)
(MGI:3808916|PMID:18692468)		 RGD PMID:18692468 MGI:3808916 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:15149599), (PMID:20160708), (PMID:7958916)
MGI:106184|MGI:109337 (PMID:11790307), (PMID:11884608), (PMID:16199867), (PMID:17476307)		 RGD PMID:7958916 PMID:11790307 PMID:11884608 PMID:15149599 PMID:16199867 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in ISO
IBA
IEA
ISS		 (PMID:20096447)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
Ensembl
UniProt		 PMID:20096447 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp9 caspase 9 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO
IBA		 (PMID:21726810)
GO_REF:0000033		 RGD
GO_Central		 PMID:21726810 GO_REF:0000033 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G E2f7 E2F transcription factor 7 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:22802528)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22802528 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23235459)		 UniProt
RGD		 PMID:23235459 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,577...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)		 RGD PMID:16213212 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16213212)
MGI:108027 (PMID:16107883)
GO_REF:0000107		 RGD
Ensembl		 PMID:16107883 PMID:16213212 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1930616 (PMID:8738145)		 Ensembl
RGD		 PMID:8738145 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:10710310) RGD PMID:10710310 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (PMID:10710310) RGD PMID:10710310 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)		 RGD
Ensembl		 PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14966270)		 UniProt
Ensembl
RGD		 PMID:14966270 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,577...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in ISO
IBA		 (PMID:15042092)
GO_REF:0000033		 RGD
GO_Central		 PMID:15042092 GO_REF:0000033 NCBI chr  X:76,353,316...76,454,502
Ensembl chr  X:76,353,760...76,454,484 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10710310)
(PMID:16213212), (PMID:16479015)		 Ensembl
RGD		 PMID:10710310 PMID:16213212 PMID:16479015 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
DNA damage response, signal transduction resulting in transcription term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17296730)		 UniProt
RGD		 PMID:17296730 GO_REF:0000024 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693 		JBrowse link
mitotic DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc7 cell division cycle 7 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Stk33 serine/threonine kinase 33 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:163,276,176...163,458,580
Ensembl chr 1:163,276,340...163,458,627 		JBrowse link
G Zfp830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3583779 (PMID:23213458)		 GO_Central
RGD		 PMID:23213458 GO_REF:0000033 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523 		JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19412162)		 UniProt
Ensembl
RGD		 PMID:19412162 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO UniProtKB:P06400 (PMID:16286473) RGD PMID:16286473 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099 		JBrowse link
G Fbxo31 F-box protein 31 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19412162)		 UniProt
Ensembl
RGD		 PMID:19412162 GO_REF:0000024 GO_REF:0000107 NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 acts_upstream_of_or_within ISO MGI:4126459 (PMID:19744960) RGD PMID:19744960 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:20173098) RGD PMID:20173098 NCBI chr19:39,235,883...39,268,479
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO (PMID:21731742) RGD PMID:21731742 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Sde2 SDE2 telomere maintenance homolog involved_in ISO
IEA		 (PMID:27906959)
GO_REF:0000107		 RGD
Ensembl		 PMID:27906959 GO_REF:0000107 NCBI chr13:92,578,843...92,595,142
Ensembl chr13:92,578,874...92,595,140 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:7958916)
(PMID:16107883)		 RGD PMID:7958916 PMID:16107883 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (PMID:18045533), (PMID:23993650) RGD PMID:18045533 PMID:23993650 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:21329877) RGD PMID:21329877 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 abraxas 1, BRCA1 A complex subunit involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,796,281...8,810,625
Ensembl chr14:8,796,266...8,810,622 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Babam1 BRISC and BRCA1 A complex member 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19261746), (PMID:19261748), (PMID:19261749)		 UniProt
GO_Central
RGD		 PMID:19261746 PMID:19261748 PMID:19261749 GO_REF:0000024 GO_REF:0000033 NCBI chr16:18,068,830...18,074,938
Ensembl chr16:18,068,884...18,074,923 		JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:19261748)		 UniProt
RGD		 PMID:19261748 GO_REF:0000024 GO_REF:0000104 NCBI chr 6:24,369,021...24,788,416
Ensembl chr 6:24,369,022...24,833,951 		JBrowse link
G Blm BLM RecQ like helicase involved_in ISO (PMID:11309417) RGD PMID:11309417 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
IBA		 (PMID:17525340), (PMID:17643121), (PMID:19261748)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:17525340 PMID:17643121 PMID:19261748 GO_REF:0000033 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17525341), (PMID:19261746), (PMID:19261748)		 UniProt
RGD		 PMID:17525341 PMID:19261746 PMID:19261748 GO_REF:0000024 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Brcc3dc BRCA1/BRCA2-containing complex, subunit 3, domain containing involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 7:44,014,889...44,016,646
Ensembl chr 7:44,005,646...44,016,670 		JBrowse link
G Brsk1 BR serine/threonine kinase 1 involved_in ISO (PMID:15150265) RGD PMID:15150265 NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365 		JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISS PMID:15150265 UniProt PMID:15150265 RGD:8554801 NCBI chr 1:197,035,505...197,088,624
Ensembl chr 1:197,035,633...197,088,092 		JBrowse link
G C1h10orf90 similar to human chromosome 10 open reading frame 90 involved_in ISO (MGI:4455105|PMID:20154723) RGD PMID:20154723 MGI:4455105 NCBI chr 1:189,059,744...189,293,353
Ensembl chr 1:189,059,746...189,293,435 		JBrowse link
G Ccng1 cyclin G1 IMP RGD PMID:9464250 RGD:2316029 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cdc14b cell division cycle 14B involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12937170)		 GO_Central
RGD		 PMID:12937170 GO_REF:0000033 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO
IEA
ISS		 (PMID:15790566)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15790566 GO_REF:0000024 GO_REF:0000107 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:23213251) RGD PMID:23213251 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek1 checkpoint kinase 1 involved_in ISO (PMID:20932473) RGD PMID:20932473 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Clspn claspin involved_in ISO
IBA		 (PMID:18662541)
GO_REF:0000033		 RGD
GO_Central		 PMID:18662541 GO_REF:0000033 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in ISO (PMID:37178686) RGD PMID:37178686 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON involved_in ISO (PMID:28191891) RGD PMID:28191891 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog involved_in ISO
IBA		 (PMID:17085480)
GO_REF:0000033		 RGD
GO_Central		 PMID:17085480 GO_REF:0000033 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Foxn3 forkhead box N3 involved_in ISO UniProtKB:P38111 (PMID:9154802) RGD PMID:9154802 NCBI chr 6:118,462,018...118,842,442
Ensembl chr 6:118,466,025...118,842,401 		JBrowse link
G Foxo4 forkhead box O4 acts_upstream_of_or_within ISO (PMID:12048180) RGD PMID:12048180 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 involved_in ISO (PMID:18662541) RGD PMID:18662541 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (PMID:20467439) RGD PMID:20467439 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase acts_upstream_of_or_within ISO MGI:2684310 (PMID:14614141) RGD PMID:14614141 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37178686)		 Ensembl
RGD		 PMID:37178686 GO_REF:0000107 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO (PMID:37178686) RGD PMID:37178686 NCBI chr  X:37,410,914...37,461,130
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3027036 (PMID:14690604)
GO_REF:0000118
GO_REF:0000033		 Ensembl
RGD
TreeGrafter
GO_Central		 PMID:14690604 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO
IBA		 (PMID:27568553)
GO_REF:0000033		 RGD
GO_Central		 PMID:27568553 GO_REF:0000033 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469 		JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA
ISS		 (PMID:11438675)
MGI:2183796 (PMID:18614044)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
InterPro
Ensembl
UniProt		 PMID:11438675 PMID:18614044 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) RGD PMID:21741933 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Plk1 polo-like kinase 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:18662541)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:18662541 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Rint1 RAD50 interactor 1 involved_in ISO (PMID:11096100) RGD PMID:11096100 NCBI chr 4:11,319,416...11,355,740
Ensembl chr 4:11,320,955...11,355,736 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor acts_upstream_of_or_within ISO MGI:3904866 (PMID:22448250) RGD PMID:22448250 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS		 (PMID:17396146)
GO_REF:0000024		 RGD
UniProt		 PMID:17396146 GO_REF:0000024 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
IEA
ISS		 (PMID:17396146)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:17396146)		 Ensembl
UniProt
RGD		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
ISS		 (PMID:23213251)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23213251 GO_REF:0000024 GO_REF:0000107 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:17525340), (PMID:17525341), (PMID:17525342), (PMID:17643121), (PMID:19261748)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17525340 PMID:17525341 PMID:17525342 PMID:17643121 PMID:19261748 GO_REF:0000024 GO_REF:0000107 NCBI chr17:9,523,793...9,592,810
Ensembl chr17:9,527,794...9,592,799 		JBrowse link
mitotic intra-S DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO
IEA
ISS		 (PMID:15916964)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15916964 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:11298456) RGD PMID:11298456 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Fancd2 FA complementation group D2 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412 		JBrowse link
G Hus1 HUS1 checkpoint clamp component involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3027036 (PMID:14690604), (PMID:18614044)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:14690604 PMID:18614044 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103557 (PMID:15533840)		 Ensembl
RGD		 PMID:15533840 GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:202,790,295...202,796,008
Ensembl chr 1:202,790,466...202,795,843 		JBrowse link
G Nek11 NIMA-related kinase 11 involved_in ISO
IBA		 (PMID:15161910)
GO_REF:0000033		 RGD
GO_Central		 PMID:15161910 GO_REF:0000033 NCBI chr 8:105,767,230...106,026,676
Ensembl chr 8:105,770,548...106,026,676 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component involved_in ISO (PMID:15538388) RGD PMID:15538388 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
UniProtKB:P26306 (PMID:9766521)		 GO_Central
RGD		 PMID:9766521 GO_REF:0000033 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:34,217,868...34,248,380
Ensembl chr12:34,218,024...34,248,372 		JBrowse link
G Tipin timeless interacting protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:17102137)		 UniProt
RGD		 PMID:17102137 GO_REF:0000024 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:101816 (PMID:15533840) RGD PMID:15533840 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
negative regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 involved_in ISO (PMID:23728299) RGD PMID:23728299 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Chek2 checkpoint kinase 2 IMP RGD PMID:20637979 RGD:10401658 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO
IEA		 (PMID:17045821)
(MGI:3690285|PMID:17045821)
GO_REF:0000107		 RGD
Ensembl		 PMID:17045821 GO_REF:0000107 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:17045821)
(MGI:3690285|PMID:17045821)
GO_REF:0000107
GO_REF:0000033		 BHF-UCL
RGD
Ensembl
GO_Central		 PMID:17045821 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3690285 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO
IEA		 (MGI:5318016|PMID:20736167)
GO_REF:0000107		 RGD
Ensembl		 PMID:20736167 GO_REF:0000107 MGI:5318016 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4838949|PMID:20167603)		 Ensembl
RGD		 PMID:20167603 GO_REF:0000107 MGI:4838949 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISO
IEA
ISS		 (PMID:29295817)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29295817 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:10360174), (PMID:9529249) RGD PMID:9529249 PMID:10360174 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16023600)		 UniProt
Ensembl
RGD		 PMID:16023600 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:11672523) RGD PMID:11672523 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (PMID:20817677) RGD PMID:20817677 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 involved_in ISO UniProtKB:Q15554 (PMID:23426265) RGD PMID:23426265 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
positive regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23352644) RGD PMID:23352644 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Tti1 TELO2 interacting protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:36724785)		 Ensembl
RGD		 PMID:36724785 GO_REF:0000107 NCBI chr 3:146,639,048...146,682,945
Ensembl chr 3:146,639,054...146,682,847 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO
IEA		 (PMID:20599664)
GO_REF:0000107		 RGD
Ensembl		 PMID:20599664 GO_REF:0000107 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) RGD PMID:9925639 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (PMID:15680327) RGD PMID:15680327 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335) RGD PMID:16269335 MGI:5297787 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19197340)		 UniProt
RGD		 PMID:19197340 GO_REF:0000024 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO
IEA		 (PMID:15102863)
GO_REF:0000107
(MGI:2679929|PMID:14500851)		 RGD
Ensembl		 PMID:14500851 PMID:15102863 GO_REF:0000107 MGI:2679929 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:15251430) RGD PMID:15251430 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (PMID:17700068) RGD PMID:17700068 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:15342622) RGD PMID:15342622 NCBI chr 3:57,130,539...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
regulation of DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5567851|PMID:24489120)		 UniProt
RGD		 PMID:24489120 GO_REF:0000024 MGI:5567851 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO MGI:3851025 (PMID:19481525) RGD PMID:19481525 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G ENSRNOG00000069571 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr  X:34,530,495...34,531,833 JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO
IBA		 (PMID:27723717), (PMID:27723720)
GO_REF:0000033		 RGD
GO_Central		 PMID:27723717 PMID:27723720 GO_REF:0000033 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104 		JBrowse link
G Fbxo4 F-box protein 4 acts_upstream_of_or_within ISO MGI:5301830 (PMID:21911473) RGD PMID:21911473 NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792 		JBrowse link
G Fem1b fem-1 homolog B involved_in ISS
ISO		 GO_REF:0000024
(PMID:19330022)		 UniProt
RGD		 PMID:19330022 GO_REF:0000024 NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Nek1 NIMA-related kinase 1 involved_in ISO (MGI:5619475|PMID:18843199) RGD PMID:18843199 MGI:5619475 NCBI chr16:28,998,229...29,125,426
Ensembl chr16:28,998,231...29,117,723 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 involved_in ISO (PMID:21504906) RGD PMID:21504906 NCBI chr19:39,235,883...39,268,479
Ensembl chr19:39,236,787...39,268,479 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4432164 (PMID:22802351)		 Ensembl
RGD		 PMID:22802351 GO_REF:0000107 NCBI chr15:36,541,200...36,592,016
Ensembl chr15:36,541,218...36,584,118 		JBrowse link
G Rpa2 replication protein A2 involved_in ISO
ISS		 (PMID:21504906)
GO_REF:0000024		 RGD
UniProt		 PMID:21504906 GO_REF:0000024 NCBI chr 5:144,976,789...144,989,445
Ensembl chr 5:144,976,748...144,987,350 		JBrowse link
G Wdr76 WD repeat domain 76 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G ENSRNOG00000067141 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr10:31,086,733...31,087,921 JBrowse link
G Kmt5a lysine methyltransferase 5A involved_in ISO
IBA		 (PMID:17707234)
GO_REF:0000033		 RGD
GO_Central		 PMID:17707234 GO_REF:0000033 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Kmt5al2 lysine methyltransferase 5A like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO MGI:98834 (PMID:16199867) RGD PMID:16199867 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Smyd2 SET and MYND domain containing 2 involved_in ISO
ISS		 (PMID:17108971)
GO_REF:0000024		 RGD
UniProt		 PMID:17108971 GO_REF:0000024 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1890508 (PMID:21522133)		 Ensembl
RGD		 PMID:21522133 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (PMID:16079796), (PMID:21522133) RGD PMID:16079796 PMID:21522133 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops3 COP9 signalosome subunit 3 involved_in ISO (PMID:15861129) RGD PMID:15861129 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        intracellular signal transduction 2864
          signal transduction in response to DNA damage 191
            DNA damage checkpoint signaling + 126
            DNA damage response, signal transduction by p53 class mediator + 75
            DNA damage response, signal transduction resulting in transcription + 17
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        signaling 7775
          signal transduction 7209
            intracellular signal transduction 2864
              signal transduction in response to DNA damage 191
                DNA damage checkpoint signaling + 126
                DNA damage response, signal transduction by p53 class mediator + 75
                DNA damage response, signal transduction resulting in transcription + 17
paths to the root